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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2870
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Igf2
Name: insulin-like growth factor 2
Acc ID: CHEBI:16598
Term: DDE
Definition: A chlorophenylethylene that is ethylene substituted by two 4-chlorophenyl groups at position 1 and two chlorine atoms at position 2.
Chemical ID: MESH:D003633
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Igf2decreases expressionEXP 6480464CTDDichlorodiphenyl Dichloroethylene results in decreased expression of IGF2 mRNAPMID:28867213
Igf2decreases methylationEXP 6480464CTDDichlorodiphenyl Dichloroethylene results in decreased methylation of IGF2 genePMID:25187598 PMID:28867213
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