Sh2d4a (SH2 domain containing 4A) - Rat Genome Database

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Gene: Sh2d4a (SH2 domain containing 4A) Rattus norvegicus
Analyze
Symbol: Sh2d4a
Name: SH2 domain containing 4A
RGD ID: 1307991
Description: Predicted to enable phosphatase binding activity. Predicted to be located in cytosol. Predicted to be active in cytoplasm. Orthologous to human SH2D4A (SH2 domain containing 4A); INTERACTS WITH 1,3-dinitrobenzene; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC306376; SH2 domain-containing 4A; SH2 domain-containing protein 4A
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81626,106,721 - 26,176,069 (-)NCBIGRCr8
mRatBN7.21621,339,010 - 21,409,360 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1621,340,015 - 21,409,260 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1624,719,964 - 24,789,247 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01628,151,974 - 28,221,432 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01624,085,301 - 24,154,602 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01623,084,247 - 23,156,825 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1623,083,954 - 23,156,962 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01622,972,707 - 23,044,750 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41622,957,569 - 23,027,864 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11622,957,570 - 23,027,862 (-)NCBI
Celera1621,499,092 - 21,568,252 (-)NCBICelera
Cytogenetic Map16p14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
(1->4)-beta-D-glucan  (ISO)
1,3-dinitrobenzene  (EXP)
17beta-estradiol  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,5-hexanedione  (EXP)
2-hydroxypropanoic acid  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3H-1,2-dithiole-3-thione  (EXP)
4,4'-sulfonyldiphenol  (ISO)
acrylamide  (EXP)
all-trans-retinoic acid  (ISO)
benomyl  (EXP)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
Benzo[k]fluoranthene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP)
bromobenzene  (EXP)
cadmium dichloride  (ISO)
calcitriol  (ISO)
CGP 52608  (ISO)
chlordecone  (ISO)
chloroprene  (ISO)
chlorpyrifos  (ISO)
chromium(6+)  (ISO)
cobalt dichloride  (EXP)
coumarin  (ISO)
cyclosporin A  (ISO)
DDE  (EXP)
dexamethasone  (ISO)
dibutyl phthalate  (EXP)
dorsomorphin  (ISO)
flutamide  (EXP)
gentamycin  (EXP)
indometacin  (ISO)
leflunomide  (EXP,ISO)
lipopolysaccharide  (ISO)
mercury dibromide  (ISO)
N-ethyl-N-nitrosourea  (ISO)
nefazodone  (EXP)
nimesulide  (EXP)
oxaliplatin  (EXP)
ozone  (ISO)
paracetamol  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
rac-lactic acid  (ISO)
rotenone  (EXP)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
sodium arsenite  (ISO)
sunitinib  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone  (ISO)
tetrachloromethane  (ISO)
thioacetamide  (EXP)
topotecan  (EXP)
trichloroethene  (EXP)
trichostatin A  (ISO)
trimellitic anhydride  (ISO)
Triptolide  (ISO)
troglitazone  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA,ISO,ISS)
cytosol  (IEA,ISO)

Molecular Function
phosphatase binding  (IBA,ISO,ISS)
protein binding  (ISO)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:15489334   PMID:17251388   PMID:19389623   PMID:31904090  


Genomics

Comparative Map Data
Sh2d4a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81626,106,721 - 26,176,069 (-)NCBIGRCr8
mRatBN7.21621,339,010 - 21,409,360 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1621,340,015 - 21,409,260 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1624,719,964 - 24,789,247 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01628,151,974 - 28,221,432 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01624,085,301 - 24,154,602 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01623,084,247 - 23,156,825 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1623,083,954 - 23,156,962 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01622,972,707 - 23,044,750 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41622,957,569 - 23,027,864 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11622,957,570 - 23,027,862 (-)NCBI
Celera1621,499,092 - 21,568,252 (-)NCBICelera
Cytogenetic Map16p14NCBI
SH2D4A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38819,313,693 - 19,396,218 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl819,313,693 - 19,396,218 (+)EnsemblGRCh38hg38GRCh38
GRCh37819,171,204 - 19,253,729 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36819,215,483 - 19,297,596 (+)NCBINCBI36Build 36hg18NCBI36
Build 34819,215,486 - 19,297,594NCBI
Celera818,134,620 - 18,217,068 (+)NCBICelera
Cytogenetic Map8p21.3NCBI
HuRef817,711,708 - 17,794,051 (+)NCBIHuRef
CHM1_1819,372,569 - 19,455,187 (+)NCBICHM1_1
T2T-CHM13v2.0819,578,579 - 19,661,102 (+)NCBIT2T-CHM13v2.0
Sh2d4a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39868,729,180 - 68,800,356 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl868,729,219 - 68,800,351 (+)EnsemblGRCm39 Ensembl
GRCm38868,276,528 - 68,347,704 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl868,276,567 - 68,347,699 (+)EnsemblGRCm38mm10GRCm38
MGSCv37870,800,427 - 70,871,603 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36871,205,517 - 71,277,048 (+)NCBIMGSCv36mm8
Celera870,819,013 - 70,892,695 (+)NCBICelera
Cytogenetic Map8B3.3NCBI
cM Map833.76NCBI
Sh2d4a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540343,111,804 - 43,170,397 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540343,111,804 - 43,170,344 (+)NCBIChiLan1.0ChiLan1.0
SH2D4A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2737,793,026 - 37,875,297 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1813,518,712 - 13,601,393 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0818,536,774 - 18,619,073 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1815,486,658 - 15,568,497 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl815,486,659 - 15,568,497 (+)Ensemblpanpan1.1panPan2
SH2D4A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11622,138,555 - 22,209,326 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1622,143,602 - 22,209,341 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1622,644,579 - 22,715,648 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01623,878,894 - 23,950,089 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1623,879,595 - 23,951,068 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11622,237,393 - 22,308,413 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01622,822,486 - 22,893,799 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01622,875,425 - 22,946,531 (+)NCBIUU_Cfam_GSD_1.0
Sh2d4a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494314,934,352 - 14,997,796 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365553,572,694 - 3,636,161 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365553,572,723 - 3,634,484 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC100518097
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11712,506,451 - 12,588,526 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21710,284,074 - 10,325,874 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SH2D4A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1817,401,254 - 17,484,141 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl817,406,951 - 17,484,839 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605224,765,241 - 24,848,022 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sh2d4a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475815,132,839 - 15,191,795 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475815,132,580 - 15,195,063 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Sh2d4a
468 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:135
Count of miRNA genes:102
Interacting mature miRNAs:123
Transcripts:ENSRNOT00000018543
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631561Hcuc2Hepatic copper content QTL 22.8liver copper amount (VT:0003065)liver total copper weight (CMO:0001507)16139533949Rat
1582235Insul8Insulin level QTL 83.30.0063blood insulin amount (VT:0001560)calculated serum insulin level (CMO:0000359)16126727669Rat
70215Niddm29Non-insulin dependent diabetes mellitus QTL 293.54blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)161900443575226532Rat
2307172Activ4Activity QTL 43.710.00023locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)16133418960Rat
1354584Despr6Despair related QTL 63.10.0067locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)16139533930Rat
2302380Slep6Serum leptin concentration QTL 63.36blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)16132139025Rat
737819Hcas4Hepatocarcinoma susceptibility QTL 44.43liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)16422760946975965Rat
9590151Scort8Serum corticosterone level QTL 88.450.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)16130836262Rat
1354625Despr7Despair related QTL 73.160.016locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)16144977551Rat
61338Bp23Blood pressure QTL 234.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16422760949227609Rat
61405Niddm6Non-insulin dependent diabetes mellitus QTL 63.660.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)16422760948972724Rat
631830Alc7Alcohol consumption QTL 72.9consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16126727669Rat
7411664Foco30Food consumption QTL 30110.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)16144588133Rat
1600378Arunc4Aerobic running capacity QTL 40.03exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)1638024580345693Rat
70183BpQTLcluster13Blood pressure QTL cluster 133.654arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)16422760943025077Rat
1600369Hcas8Hepatocarcinoma susceptibility QTL 8liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)16122477621Rat
737826Alc11Alcohol consumption QTL 113.2consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16422760960252231Rat
2303566Bw90Body weight QTL 902body mass (VT:0001259)body weight (CMO:0000012)16139533930Rat
2312663Slep9Serum leptin concentration QTL 90.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)1683223659492508Rat
2306902Bp339Blood pressure QTL 3390.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16338015043025077Rat
1300133Rf24Renal function QTL 243.64blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)16338015021361552Rat
2312660Bw95Body weight QTL 950.05inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)1683223659492508Rat
2312666Insul16Insulin level QTL 160.01blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1683223659492508Rat
634355Rends4Renal damage susceptibility QTL 40.05kidney blood vessel morphology trait (VT:0000530)organ lesion measurement (CMO:0000677)16126727669Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor diameter (CMO:0001889)161769679182635055Rat
2293343Glom16Glomerulus QTL 167.4kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)1683223646053497Rat
6903319Bw114Body weight QTL 1142.70.0037body mass (VT:0001259)body weight (CMO:0000012)16143534949Rat
2312669Stl23Serum triglyceride level QTL 230.01blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)1683223659492508Rat

Markers in Region
D16Rat76  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21621,361,414 - 21,361,552 (+)MAPPERmRatBN7.2
Rnor_6.01623,105,700 - 23,105,837NCBIRnor6.0
Rnor_5.01622,994,160 - 22,994,297UniSTSRnor5.0
RGSC_v3.41622,978,935 - 22,979,073RGDRGSC3.4
RGSC_v3.41622,978,936 - 22,979,073UniSTSRGSC3.4
RGSC_v3.11622,978,933 - 22,979,071RGD
Celera1621,520,505 - 21,520,642UniSTS
RH 3.4 Map16269.8RGD
RH 3.4 Map16269.8UniSTS
RH 2.0 Map16301.8RGD
SHRSP x BN Map169.04RGD
Cytogenetic Map16p14UniSTS
RH129030  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21621,360,498 - 21,360,682 (+)MAPPERmRatBN7.2
Rnor_6.01623,104,784 - 23,104,967NCBIRnor6.0
Rnor_5.01622,993,244 - 22,993,427UniSTSRnor5.0
RGSC_v3.41622,978,020 - 22,978,203UniSTSRGSC3.4
Celera1621,519,589 - 21,519,772UniSTS
RH 3.4 Map16262.3UniSTS
Cytogenetic Map16p14UniSTS
AA925855  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21621,340,098 - 21,340,303 (+)MAPPERmRatBN7.2
Rnor_6.01623,084,340 - 23,084,544NCBIRnor6.0
Rnor_5.01622,972,800 - 22,973,004UniSTSRnor5.0
RGSC_v3.41622,957,662 - 22,957,866UniSTSRGSC3.4
Celera1621,499,185 - 21,499,389UniSTS
RH 3.4 Map16256.76UniSTS
Cytogenetic Map16p14UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000018543   ⟹   ENSRNOP00000018543
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1621,340,015 - 21,409,260 (-)Ensembl
Rnor_6.0 Ensembl1623,083,954 - 23,156,962 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000112358   ⟹   ENSRNOP00000083552
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1621,340,015 - 21,394,624 (-)Ensembl
RefSeq Acc Id: NM_001012048   ⟹   NP_001012048
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81626,106,721 - 26,175,974 (-)NCBI
mRatBN7.21621,340,006 - 21,409,260 (-)NCBI
Rnor_6.01623,084,247 - 23,156,825 (-)NCBI
Rnor_5.01622,972,707 - 23,044,750 (-)NCBI
RGSC_v3.41622,957,569 - 23,027,864 (-)RGD
Celera1621,499,092 - 21,568,252 (-)RGD
Sequence:
RefSeq Acc Id: XM_039094496   ⟹   XP_038950424
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81626,106,721 - 26,176,069 (-)NCBI
mRatBN7.21621,339,010 - 21,409,360 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001012048 (Get FASTA)   NCBI Sequence Viewer  
  XP_038950424 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH79100 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000018543.3
  ENSRNOP00000083552.1
  ENSRNOP00060021141
  ENSRNOP00065004951
GenBank Protein Q6AYC8 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001012048   ⟸   NM_001012048
- UniProtKB: Q6AYC8 (UniProtKB/Swiss-Prot),   A0A8I5ZXE8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000018543   ⟸   ENSRNOT00000018543
RefSeq Acc Id: XP_038950424   ⟸   XM_039094496
- Peptide Label: isoform X1
- UniProtKB: Q6AYC8 (UniProtKB/Swiss-Prot),   A0A8I5ZXE8 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000083552   ⟸   ENSRNOT00000112358
Protein Domains
SH2

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6AYC8-F1-model_v2 AlphaFold Q6AYC8 1-422 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700060
Promoter ID:EPDNEW_R10583
Type:multiple initiation site
Name:Sh2d4a_1
Description:SH2 domain containing 4A
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01623,156,928 - 23,156,988EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1307991 AgrOrtholog
BioCyc Gene G2FUF-11687 BioCyc
Ensembl Genes ENSRNOG00000013541 Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00060015405 UniProtKB/Swiss-Prot
  ENSRNOG00065004903 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000018543.6 UniProtKB/Swiss-Prot
  ENSRNOT00000112358.1 UniProtKB/TrEMBL
  ENSRNOT00060026442 UniProtKB/Swiss-Prot
  ENSRNOT00065007141 UniProtKB/Swiss-Prot
Gene3D-CATH 3.30.505.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7124466 IMAGE-MGC_LOAD
InterPro SH2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH2_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:306376 UniProtKB/Swiss-Prot
MGC_CLONE MGC:94080 IMAGE-MGC_LOAD
NCBI Gene 306376 ENTREZGENE
PANTHER SH2 DOMAIN-CONTAINING PROTEIN 4A UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  T CELL-SPECIFIC ADAPTER PROTEIN TSAD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam SH2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Sh2d4a PhenoGen
PRINTS SH2DOMAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE SH2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000013541 RatGTEx
  ENSRNOG00060015405 RatGTEx
  ENSRNOG00065004903 RatGTEx
SMART SH2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF55550 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I5ZXE8 ENTREZGENE, UniProtKB/TrEMBL
  Q6AYC8 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-12-06 Sh2d4a  SH2 domain containing 4A  Sh2d4a_predicted  SH2 domain containing 4A (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Sh2d4a_predicted  SH2 domain containing 4A (predicted)      Symbol and Name status set to approved 70820 APPROVED