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Gene: Stxbp1 (syntaxin binding protein 1) Rattus norvegicus
Symbol: Stxbp1
Name: syntaxin binding protein 1
Description: Exhibits several functions, including enzyme binding activity; identical protein binding activity; and syntaxin-1 binding activity. Involved in several processes, including positive regulation of glutamate secretion, neurotransmission; protein stabilization; and regulation of vesicle-mediated transport. Localizes to several cellular components, including axon; perinuclear region of cytoplasm; and postsynapse. Human ortholog(s) of this gene implicated in West syndrome and early infantile epileptic encephalopathy 4. Orthologous to human STXBP1 (syntaxin binding protein 1); PARTICIPATES IN insulin secretion pathway; synaptic vesicle exocytosis - neurotransmitter release pathway; INTERACTS WITH 1,3-dinitrobenzene; 2-ethoxyethanol; 2-methoxyethanol.
Type: protein-coding
Also known as: ANC18HA; Munc18-1; n-sec1; nSec1; NSEC1A; p67; protein unc-18 homolog 1; protein unc-18 homolog A; rbSec1; rbSec1A; rbSec1B; Sec1; syntaxin-binding protein 1; unc-18 homolog; unc-18-1; unc-18A; Unc18-1
Homo sapiens (human) : STXBP1 (syntaxin binding protein 1)  HGNC  Alliance
Mus musculus (house mouse) : Stxbp1 (syntaxin binding protein 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Stxbp1 (syntaxin binding protein 1)
Pan paniscus (bonobo/pygmy chimpanzee) : STXBP1 (syntaxin binding protein 1)
Canis lupus familiaris (dog) : STXBP1 (syntaxin binding protein 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Stxbp1 (syntaxin binding protein 1)
Sus scrofa (pig) : STXBP1 (syntaxin binding protein 1)
Chlorocebus sabaeus (African green monkey) : STXBP1 (syntaxin binding protein 1)
Heterocephalus glaber (naked mole-rat) : Stxbp1 (syntaxin binding protein 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0311,823,779 - 11,885,479 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl311,823,785 - 11,885,417 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0317,160,752 - 17,221,893 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4311,762,105 - 11,825,531 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1311,658,476 - 11,721,903 (-)NCBI
Celera310,816,317 - 10,877,576 (-)NCBICelera
Cytogenetic Map3p11NCBI
RH 3.4 Map379.6RGD
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Stxbp1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3785
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.