Genetic Models at MCW

If interested in obtaining any of these strains, please contact mcwcustomrats@mcw.edu .   

  

Genetic Models Available

Gene Symbol Gene No. of Models Background Strain Strain Symbol Aliases Method Availability Origination Phenotype Data Publications Ask about this Model!
Rag1 recombination activating 1 2
Nppa natriuretic peptide A 1 SS/JrHsdMcwi SS-Nppaem4Mcwi ZFN Live Animals; Cryopreserved Sperm (as of 2017-01-26) PhysGen Knockouts Phenominer Link Publications
Htr1a 5-hydroxytryptamine receptor 1A 2
Shc1 SHC adaptor protein 1 4
Acad10 acyl-CoA dehydrogenase family, member 10 2
Myadml2 myeloid-associated differentiation marker-like 2 1 SS/JrHsdMcwi SS-Myadml2em5Mcwi ZFN Cryopreserved Sperm (as of 2017-01-26) PhysGen Knockouts Publications
Trpc3 transient receptor potential cation channel, subfamily C, member 3 2
Rasgrp3 RAS guanyl releasing protein 3 2
Enox1 ecto-NOX disulfide-thiol exchanger 1 1 F344/NCrl F344-Enox1Tn(sb-T2/Bart3)2.282Mcwi RRRC:0470 Sleeping Beauty Cryopreserved Sperm (as of 2017-01-26) PhysGen Publications
Btg2 BTG anti-proliferation factor 2 4
Kcnj16 potassium voltage-gated channel subfamily J member 16 1 SS/JrHsdMcwi SS-Kcnj16em1Mcwi ZFN Live Animals; Cryopreserved Sperm (as of 2017-01-26) PhysGen Knockouts Publications
Slc8a2 solute carrier family 8 member A2 1 FHH/EurMcwi FHH-Slc8a2m1Mcwi RRRC:00404 ENU Cryopreserved Sperm (as of 2017-01-26) PhysGen Phenominer Link
Patj PATJ, crumbs cell polarity complex component 1 F344/NCrl F344-PatjTn(sb-T2/Bart3)2.343Mcwi F344-InadlTn(sb-T2/Bart3)2.343Mcwi ;
RRRC: 0480
Sleeping Beauty Cryopreserved Sperm (as of 2017-01-26) PhysGen Publications
Abcb1b ATP-binding cassette, subfamily B (MDR/TAP), member 1B 1 SS/JrHsdMcwi SS-Abcb1bem2Mcwi ZFN Cryopreserved Sperm (as of 2017-07-24) PhysGen Knockouts Publications
Mylip myosin regulatory light chain interacting protein 2
Adgrl3 adhesion G protein-coupled receptor L3 1 F344/NCrl F344-Lphn3Tn(sb-T2/Bart3)2.151Mcwi RRRC:0334 Sleeping Beauty Cryopreserved Sperm (as of 2017-01-13) PhysGen Publications
Inpp4b inositol polyphosphate-4-phosphatase type II B 1 F344/NCrl F344-Inpp4bTn(sb-T2/Bart3)2.143Mcwi RRRC:0379 Sleeping Beauty Cryopreserved Sperm (as of 2017-01-26) PhysGen Phenominer Link Publications
Slc24a3 solute carrier family 24 member 3 2
Mir29b1 microRNA 29b-1 1 SS-Chr 13BN/Mcwi SS-Chr 13BN-Mir29bem1Mcwi TALEN Live Animals (as of 2017-01-26) PhysGen Knockouts Publications
Gng12 G protein subunit gamma 12 1 F344/NCrl F344-Gng12Tn(sb-T2/Bart3)2.320Mcwi RRRC:0454 Sleeping Beauty Cryopreserved Sperm (as of 2017-01-26) PhysGen Publications
Nfe2l2 nuclear factor, erythroid 2-like 2 2
Syndig1 synapse differentiation inducing 1 1 F344/NCrl F344-Syndig1Tn(sb-T2/Bart3)2.171Mcwi F344-RGD1310753Tn(sb-T2/Bart3)2.171Mcwi ;
RRRC:00342
Sleeping Beauty Cryopreserved Sperm (as of 2017-01-26) PhysGen Publications
Axl Axl receptor tyrosine kinase 2
Grk1 G protein-coupled receptor kinase 1 1 F344/NCrl F344-Grk1Tn(sb-T2/Bart3)2.234Mcwi RRRC: 0388 Sleeping Beauty Cryopreserved Sperm (as of 2017-01-26) PhysGen Publications
Sptbn4 spectrin, beta, non-erythrocytic 4 1 F344/NCrl F344-Sptbn4Tn(sb-T2/Bart3)2.179Mcwi F344-Spnb4Tn(sb-T2/Bart3)2.179Mcwi ;
F344-Spnb4Tn(sb-T2/Bart3)2.179Mcwi
Sleeping Beauty Unknown PGA Publications
Dlg1 discs large MAGUK scaffold protein 1 1 F344/NCrl F344-Dlg1Tn(sb-T2/Bart3)2.133Mcwi Sleeping Beauty Unknown PGA Publications
Pparg peroxisome proliferator-activated receptor gamma 1 SS/JrHsdMcwi SS-Ppargem1Mcwi ZFN Cryopreserved Sperm (as of 2017-01-26) PhysGen Knockouts Publications
Dnah11 dynein, axonemal, heavy chain 11 1 F344/NCrl F344-Dnah11Tn(sb-T2/Bart3)2.293Mcwi RRRC:0429 Sleeping Beauty Cryopreserved Sperm (as of 2017-01-26) PhysGen Publications
Chrna5 cholinergic receptor nicotinic alpha 5 subunit 1 LEW/NCrl LEW-Chrna5em2Mcwi CRISPR/Cas9 Cryorecovery (as of 2017-07-18) MCW Gene Editing Rat Resource Center
Lims1 LIM zinc finger domain containing 1 1 F344/NCrl F344-Lims1Tn(sb-T2/Bart3)2.169Mcwi F344-RGD1560732Tn(sb-T2/Bart3)2.169Mcwi ;
F344-RGD1560732_predictedTn(sb-T2/Bart3)2.169Mcwi ;
F344-RGD1560732_predictedTn(sb-T2/Bart3)2.169Mcwi ;
RRRC:0362
Sleeping Beauty Cryopreserved Sperm (as of 2017-01-26) PhysGen Phenominer Link Publications
Mthfr methylenetetrahydrofolate reductase 1 SS/JrHsdMcwi SS-Mthfrem1Mcwi ZFN Cryopreserved Sperm (as of 2017-01-26) PhysGen Knockouts Phenominer Link Publications
Slc27a5 solute carrier family 27 member 5 1 BN/NHsdMcwi BN-Slc27a5m2Mcwi ENU Unknown PGA
Gramd1b GRAM domain containing 1B 1 F344/NCrl F344-Gramd1bTn(sb-T2/Bart3)2.287Mcwi RRRC: 0389 Sleeping Beauty Cryopreserved Sperm (as of 2017-01-26) PhysGen Publications
Trafd1 TRAF type zinc finger domain containing 1 1 SS/JrHsdMcwi SS-Trafd1em1Mcwi ZFN Cryopreserved Sperm (as of 2017-01-26) PhysGen Knockouts Publications
Slc7a9 solute carrier family 7 member 9 2
Fam19a2 family with sequence similarity 19 member A2, C-C motif chemokine like 1 F344/NCrl F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi F344-LOC680647Tn(sb-T2/Bart3)2.184Mcwi ;
F344-LOC680647Tn(sb-T2/Bart3)2.184Mcwi ;
RRRC:0387
Sleeping Beauty Cryopreserved Sperm (as of 2017-01-26) PhysGen Phenominer Link Publications
Pkhd1 PKHD1, fibrocystin/polyductin 1 PCK-Pkhd1pck/CrljCrl PCK-P2rx7em8Mcwi CRISPR/Cas9 Live Animals (as of 2017-02-20) MCW Gene Editing Rat Resource Center
Fah fumarylacetoacetate hydrolase 1 Crl:SD SD-Fahem3Mcwi TALEN Cryorecovery (as of 2017-07-18) PhysGen Knockouts Publications
Tcf7l2 transcription factor 7 like 2 1 SS/JrHsdMcwi SS-Tcf7l2em1Mcwi ZFN Cryopreserved Sperm (as of 2017-01-26) PhysGen Knockouts Phenominer Link Publications
Exoc4 exocyst complex component 4 1 F344/NCrl F344-Exoc4Tn(sb-T2/Bart3)2.317Mcwi RRRC:0456 Sleeping Beauty Cryopreserved Sperm (as of 2017-01-26) PhysGen Publications
Myo9a myosin IXA 1 F344/NCrl F344-Myo9aTn(sb-T2/Bart3)2.186Mcwi RRRC:00385 Sleeping Beauty Cryopreserved Sperm (as of 2017-01-26) PhysGen Phenominer Link Publications
Pebp4 phosphatidylethanolamine binding protein 4 1 F344/NCrl F344-Pebp4Tn(sb-T2/Bart3)2.299Mcwi RRRC: 0455 Sleeping Beauty Cryopreserved Sperm (as of 2017-01-26) PhysGen Publications
Cacna1g calcium voltage-gated channel subunit alpha1 G 1 SS/JrHsdMcwi SS-Cacna1gm1Mcwi ENU Unknown PGA
Lep leptin 1 SS/JrHsdMcwi SS-Lepem5Mcwi ZFN Cryopreserved Sperm (as of 2017-01-26) PhysGen Knockouts Publications