Genetic Models at MCW

If interested in obtaining any of these strains, please contact mcwcustomrats@mcw.edu .   

  

Genetic Models Available

Gene Symbol Gene No. of Models Background Strain Strain Symbol Aliases Method Availability Origination Phenotype Data Publications Ask about this Model!
Cd247 Cd247 molecule 2
Plod1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 1 SS/JrHsdMcwi SS-Plod1em1Mcwi ZFN Cryorecovery (as of 2017-01-26) PhysGen Knockouts Phenominer Link Publications
Pkd1 polycystin 1, transient receptor potential channel interacting 2
Lepr leptin receptor 1 SS/JrHsdMcwi SS-Leprem2Mcwi ZFN Cryopreserved Sperm (as of 2017-01-26) PhysGen Knockouts Publications
Cst3 cystatin C 3
Trdn triadin 1 F344/NCrl F344-TrdnTn(sb-T2/Bart3)2.238Mcwi RRRC:00368 Sleeping Beauty Cryopreserved Sperm (as of 2017-01-26) PhysGen Publications
Cdh13 cadherin 13 1 SS/JrHsdMcwi SS-Cdh13em1Mcwi ZFN Cryorecovery (as of 2017-01-26) PhysGen Knockouts Phenominer Link Publications
Prune1 prune exopolyphosphatase 1 2
Cpt2 carnitine palmitoyltransferase 2 1 SS/JrHsdMcwi SS-Cpt2m1Mcwi RRRC:00416 ENU Cryopreserved Sperm (as of 2017-01-26) PhysGen Phenominer Link
Ccr2 C-C motif chemokine receptor 2 1 FHH/EurMcwi FHH-Ccr2m1Mcwi RRRC:00399 ENU Cryopreserved Sperm (as of 2017-01-26) PhysGen Phenominer Link
Agbl4 ATP/GTP binding protein-like 4 1 F344/NCrl F344-Agbl4Tn(sb-T2/Bart3)2.337Mcwi RRRC:0473 Sleeping Beauty Cryopreserved Sperm (as of 2017-01-26) PhysGen Publications
Fam19a2 family with sequence similarity 19 member A2, C-C motif chemokine like 1 F344/NCrl F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi F344-LOC680647Tn(sb-T2/Bart3)2.184Mcwi ;
F344-LOC680647Tn(sb-T2/Bart3)2.184Mcwi ;
RRRC:0387
Sleeping Beauty Cryopreserved Sperm (as of 2017-01-26) PhysGen Phenominer Link Publications
Ldlr low density lipoprotein receptor 2
Pon1 paraoxonase 1 2
Asip agouti signaling protein 1 ACI.FHH-(D1Mit18-D1Rat90)(D14Mit11-D14Rat33)(D14Rat65-D14Rat90)/EurMcwi ACI.FHH-(D1Mit18-D1Rat90)(D14Mit11-D14Rat33)(D14Rat65-D14Rat90)/EurMcwi-Asipem1Mcwi ACI.FHH-(D1Mit18-D1Rat90)(D14Mit11-D14Rat33)(D14Rat65-D14Rat90EurMcwi-Asipem1Mcwi;Rf-1A+4-Asipem1Mcwi ZFN Cryopreserved Sperm (as of 2017-01-26) PhysGen Knockouts Publications
Chrnb4 cholinergic receptor nicotinic beta 4 subunit 1 LEW/NCrl LEW-Chrnb4em5Mcwi Strain00418 CRISPR/Cas9 Live Animals; Cryorecovery (as of 2017-08-02) MCW Gene Editing Rat Resource Center
Trpc6 transient receptor potential cation channel, subfamily C, member 6 3
Pkhd1 polycystic kidney and hepatic disease 1 1 PCK/CrljCrl-Pkhd1pck/Crl PCK-P2rx7em8Mcwi CRISPR/Cas9 Live Animals (as of 2017-02-20) MCW Gene Editing Rat Resource Center
Nrxn2 neurexin 2 1 F344/NCrl F344-Nrxn2Tn(sb-T2/Bart3)2.250Mcwi RRRC:00449 Sleeping Beauty Cryopreserved Sperm (as of 2017-01-26) PhysGen Publications
Lpin1 lipin 1 1 SS/JrHsdMcwi SS-Lpin1em1Mcwi ZFN Cryopreserved Sperm (as of 2017-01-26) PhysGen Knockouts Publications
Cyba cytochrome b-245 alpha chain 1 SS/JrHsdMcwi SS-Cybaem1Mcwi ZFN Live Animals; Cryopreserved Sperm (as of 2017-01-26) PhysGen Knockouts Phenominer Link Publications
Immp1l inner mitochondrial membrane peptidase subunit 1 1 F344/NCrl F344-Immp1lTn(sb-T2/Bart3)2.246Mcwi RRRC: 0355 Sleeping Beauty Cryopreserved Sperm (as of 2017-01-26) PhysGen Publications
Csmd3 CUB and Sushi multiple domains 3 1 F344/NCrl F344-Csmd3Tn(sb-T2/Bart3)2.288Mcwi RRRC:0390 Sleeping Beauty Cryopreserved Sperm (as of 2017-01-26) PhysGen Publications
Sorcs1 sortilin-related VPS10 domain containing receptor 1 2
Erbb4 erb-b2 receptor tyrosine kinase 4 1 F344/NCrl F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi RRRC:0383 Sleeping Beauty Cryopreserved Sperm (as of 2017-01-26) PhysGen Phenominer Link Publications
Lrrc7 leucine rich repeat containing 7 1 F344/NCrl F344-Lrrc7Tn(sb-T2/Bart3)2.253Mcwi RRRC:00360 Sleeping Beauty Cryopreserved Sperm (as of 2017-01-26) PhysGen Publications
Inpp4b inositol polyphosphate-4-phosphatase type II B 1 F344/NCrl F344-Inpp4bTn(sb-T2/Bart3)2.143Mcwi RRRC:0379 Sleeping Beauty Cryopreserved Sperm (as of 2017-01-26) PhysGen Phenominer Link Publications
Sh2b3 SH2B adaptor protein 3 5
Gpr183 G protein-coupled receptor 183 3
Spta1 spectrin, alpha, erythrocytic 1 1 F344/NCrl F344-Spta1Tn(sb-T2/Bart3)2.315Mcwi RRRC:00439 Sleeping Beauty Cryopreserved Sperm (as of 2017-01-26) PhysGen Publications
Enox1 ecto-NOX disulfide-thiol exchanger 1 1 F344/NCrl F344-Enox1Tn(sb-T2/Bart3)2.282Mcwi RRRC:0470 Sleeping Beauty Cryopreserved Sperm (as of 2017-01-26) PhysGen Publications
Ccdc85a coiled-coil domain containing 85A 1 F344/NCrl F344-Ccdc85aTn(sb-T2/Bart3)2.248Mcwi RRRC:0356 Sleeping Beauty Cryopreserved Sperm (as of 2017-01-26) PhysGen Publications
P3h3 prolyl 3-hydroxylase 3 1 F344/NCrl F344-P3h3Tn(sb-T2/Bart3)2.310Mcwi F344-Leprel2Tn(sb-T2/Bart3)2.310Mcwi ;
RRRC: 0433
Sleeping Beauty Cryopreserved Sperm (as of 2017-01-26) PhysGen Publications
Apoe apolipoprotein E 1 SS/JrHsdMcwi SS-Apoeem9Mcwi ZFN Cryopreserved Sperm (as of 2017-01-26) PhysGen Knockouts Publications
Plcd3 phospholipase C, delta 3 2
Slc8a2 solute carrier family 8 member A2 1 FHH/EurMcwi FHH-Slc8a2m1Mcwi RRRC:00404 ENU Cryopreserved Sperm (as of 2017-01-26) PhysGen Phenominer Link
Pappa2 pappalysin 2 2
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 1 SS/JrHsdMcwi SS-Ptpn11em1Mcwi ZFN Cryopreserved Sperm (as of 2017-01-26) PhysGen Knockouts Publications
Acad10 acyl-CoA dehydrogenase family, member 10 2
Snx25 sorting nexin 25 1 F344/NCrl F344-Snx25Tn(sb-T2/Bart3)2.270Mcwi RRRC:00374 Sleeping Beauty Cryopreserved Sperm (as of 2017-01-26) PhysGen Publications
Rag1 recombination activating 1 2
Chsy1 chondroitin sulfate synthase 1 1 F344/NCrl F344-Chsy1Tn(sb-T2/Bart3)2.165Mcwi F344-Chsy1_predictedTn(sb-T2/Bart3)2.165Mcwi ;
F344-Chsy1_predictedTn(sb-T2/Bart3)2.165Mcwi ;
RRRC:0337
Sleeping Beauty Cryopreserved Sperm (as of 2017-01-26) PhysGen Publications
Rap1gds1 Rap1 GTPase-GDP dissociation stimulator 1 1 F344/NCrl F344-Rap1gds1Tn(sb-T2/Bart3)2.251Mcwi RRRC:00357 Sleeping Beauty Cryopreserved Sperm (as of 2017-01-26) PhysGen Publications