CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: tributylstannane
Accession: CHEBI:27086
browse the term
Definition: An organotin compound that has formula C12H28Sn.
Synonyms: related_synonym: Formula=C12H28Sn; InChI=1S/3C4H9.Sn.H/c3*1-3-4-2;;/h3*1,3-4H2,2H3;;; InChIKey=DBGVGMSCBYYSLD-UHFFFAOYSA-N; SMILES=[H][Sn](CCCC)(CCCC)CCCC; SnBu3H; TBT; Tri-n-butyltin; Tri-n-butyltin hydride; Tributyltin; [Sn(Bu)3H]
xref: Beilstein:3587329; CAS:688-73-3; Gmelin:4258
xref_mesh: MESH:C011559
xref: UM-BBD_compID:c0579
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A1BG
alpha-1-B glycoprotein
decreases expression
ISO
tributyltin results in decreased expression of A1BG mRNA
CTD
PMID:31939706
NCBI chr19:58,345,183...58,353,492
Ensembl chr19:58,345,178...58,353,492
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AASDHPPT
aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of AASDHPPT mRNA
CTD
PMID:31129395
NCBI chr11:106,077,662...106,098,695
Ensembl chr11:106,075,501...106,098,699
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ABCA1
ATP binding cassette subfamily A member 1
increases expression multiple interactions
ISO EXP
tributyltin results in increased expression of ABCA1; tributyltin results in increased expression of ABCA1 mRNA diazepinylbenzoic acid inhibits the reaction [tributyltin results in increased expression of ABCA1 mRNA] [tributyltin co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 mRNA; [tributyltin co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 protein; diazepinylbenzoic acid inhibits the reaction [[tributyltin co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 mRNA]; UVI 3003 inhibits the reaction [tributyltin results in increased expression of ABCA1 mRNA]
CTD
PMID:21622945 PMID:23824090 PMID:24356939 PMID:25932594 PMID:31006824
NCBI chr 9:104,781,006...104,928,155
Ensembl chr 9:104,781,006...104,928,155
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ABCB1
ATP binding cassette subfamily B member 1
decreases expression increases expression
ISO
tributyltin results in decreased expression of ABCB1 protein tributyltin results in increased expression of ABCB1A mRNA
CTD
PMID:26079211 PMID:31939706
NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323
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ABCG1
ATP binding cassette subfamily G member 1
increases expression
EXP
tributyltin results in increased expression of ABCG1 mRNA
CTD
PMID:23824090 PMID:24356939
NCBI chr21:42,199,689...42,297,244
Ensembl chr21:42,199,689...42,304,389
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ACAA2
acetyl-CoA acyltransferase 2
increases expression
ISO
tributyltin results in increased expression of ACAA2 mRNA
CTD
PMID:23428407
NCBI chr18:49,782,164...49,813,533
Ensembl chr18:49,782,164...49,813,953
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ACACA
acetyl-CoA carboxylase alpha
increases expression
ISO
tributyltin results in increased expression of ACACA mRNA
CTD
PMID:23428407
NCBI chr17:37,084,992...37,406,836
Ensembl chr17:37,084,992...37,406,836
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ACADL
acyl-CoA dehydrogenase long chain
increases expression
ISO
tributyltin results in increased expression of ACADL mRNA
CTD
PMID:23428407
NCBI chr 2:210,187,923...210,225,447
Ensembl chr 2:210,187,126...210,225,447
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ACADM
acyl-CoA dehydrogenase medium chain
increases expression
ISO
tributyltin results in increased expression of ACADM mRNA
CTD
PMID:23428407 PMID:24848799
NCBI chr 1:75,724,709...75,763,679
Ensembl chr 1:75,724,431...75,787,575
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ACADVL
acyl-CoA dehydrogenase very long chain
increases expression
ISO
tributyltin results in increased expression of ACADVL mRNA
CTD
PMID:23428407
NCBI chr17:7,217,125...7,225,266
Ensembl chr17:7,217,125...7,225,266
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ACAP2
ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of ACAP2 mRNA
CTD
PMID:31129395
NCBI chr 3:195,274,745...195,443,020
Ensembl chr 3:195,274,745...195,443,044
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ACAT1
acetyl-CoA acetyltransferase 1
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of ACAT1 mRNA
CTD
PMID:31129395
NCBI chr11:108,116,705...108,147,603
Ensembl chr11:108,116,695...108,148,957
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ACE
angiotensin I converting enzyme
increases expression
ISO
tributyltin results in increased expression of ACE mRNA
CTD
PMID:31939706
NCBI chr17:63,477,061...63,498,373
Ensembl chr17:63,477,061...63,498,380
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ACE2
angiotensin converting enzyme 2
increases expression
ISO
tributyltin results in increased expression of ACE2 mRNA
CTD
PMID:31939706
NCBI chr X:15,518,197...15,607,211
Ensembl chr X:15,494,566...15,607,236
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ACO2
aconitase 2
increases expression
ISO
tributyltin results in increased expression of ACO2 mRNA
CTD
PMID:23428407 PMID:24848799
NCBI chr22:41,469,117...41,528,974
Ensembl chr22:41,447,830...41,529,273
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ACOX1
acyl-CoA oxidase 1
increases expression
ISO
tributyltin results in increased expression of ACOX1 mRNA
CTD
PMID:23322813 PMID:23428407
NCBI chr17:75,941,507...75,979,166
Ensembl chr17:75,941,507...75,979,177
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ACOXL
acyl-CoA oxidase like
increases expression
ISO
tributyltin results in increased expression of ACOXL mRNA
CTD
PMID:31129395
NCBI chr 2:110,732,573...111,118,548
Ensembl chr 2:110,732,539...111,118,548
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ACSL1
acyl-CoA synthetase long chain family member 1
increases expression
ISO
tributyltin results in increased expression of ACSL1 mRNA
CTD
PMID:23428407
NCBI chr 4:184,755,595...184,826,594
Ensembl chr 4:184,755,595...184,826,818
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ACSL3
acyl-CoA synthetase long chain family member 3
increases expression
ISO
tributyltin results in increased expression of ACSL3 mRNA
CTD
PMID:23428407
NCBI chr 2:222,861,036...222,944,639
Ensembl chr 2:222,860,942...222,944,639
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ACSS1
acyl-CoA synthetase short chain family member 1
increases expression
ISO
tributyltin results in increased expression of ACSS1 mRNA
CTD
PMID:31939706
NCBI chr20:25,006,237...25,058,139
Ensembl chr20:25,006,230...25,058,980
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ACTA2
actin alpha 2, smooth muscle
increases expression
ISO
tributyltin results in increased expression of ACTA2 protein
CTD
PMID:27521499
NCBI chr10:88,935,074...88,991,337
Ensembl chr10:88,934,822...88,991,339
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ACTN1
actinin alpha 1
increases expression
EXP
tributyltin results in increased expression of ACTN1 mRNA
CTD
PMID:26314263
NCBI chr14:68,874,128...68,979,302
Ensembl chr14:68,874,123...68,979,440
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ADA
adenosine deaminase
increases expression
ISO
tributyltin results in increased expression of ADA mRNA
CTD
PMID:31939706
NCBI chr20:44,619,522...44,651,699
Ensembl chr20:44,584,896...44,652,252
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ADAM9
ADAM metallopeptidase domain 9
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of ADAM9 mRNA
CTD
PMID:31129395
NCBI chr 8:38,996,973...39,105,261
Ensembl chr 8:38,996,754...39,105,445
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ADAMTS2
ADAM metallopeptidase with thrombospondin type 1 motif 2
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of ADAMTS2 mRNA
CTD
PMID:31129395
NCBI chr 5:179,110,853...179,345,461
Ensembl chr 5:179,110,853...179,345,461
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ADAP1
ArfGAP with dual PH domains 1
increases expression
ISO
tributyltin results in increased expression of ADAP1 mRNA
CTD
PMID:31939706
NCBI chr 7:897,900...955,407
Ensembl chr 7:897,900...955,407
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ADARB1
adenosine deaminase RNA specific B1
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of ADARB1 mRNA
CTD
PMID:31129395
NCBI chr21:45,074,578...45,226,563
Ensembl chr21:45,073,853...45,226,560
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ADCY1
adenylate cyclase 1
decreases expression
ISO
tributyltin results in decreased expression of ADCY1 mRNA
CTD
PMID:31939706
NCBI chr 7:45,574,140...45,723,116
Ensembl chr 7:45,574,140...45,723,116
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ADCY2
adenylate cyclase 2
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of ADCY2 mRNA; [bisphenol A co-treated with tributyltin] results in increased expression of ADCY2 protein
CTD
PMID:31129395
NCBI chr 5:7,396,138...7,830,081
Ensembl chr 5:7,396,138...7,830,081
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ADCYAP1R1
ADCYAP receptor type I
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of ADCYAP1R1 mRNA
CTD
PMID:31129395
NCBI chr 7:31,052,308...31,111,474
Ensembl chr 7:31,052,308...31,111,474
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ADIPOQ
adiponectin, C1Q and collagen domain containing
multiple interactions decreases expression decreases secretion affects expression increases expression
ISO EXP
[triphenyltin chloride co-treated with tributyltin co-treated with dibutyldichlorotin] affects the expression of ADIPOQ protein; tributyltin promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of ADIPOQ mRNA] tributyltin promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of ADIPOQ protein]; tributyltin promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased secretion of ADIPOQ protein]; tributyltin promotes the reaction [[Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ADIPOQ protein] tributyltin results in decreased expression of ADIPOQ protein tributyltin results in decreased secretion of ADIPOQ protein tributyltin affects the expression of ADIPOQ protein tributyltin results in increased expression of ADIPOQ mRNA; tributyltin results in increased expression of ADIPOQ protein
CTD
PMID:22197818 PMID:23428407 PMID:28161095 PMID:28397090 PMID:29675927 PMID:30172001 PMID:31016361 PMID:32407875 PMID:34864131 PMID:37142754 More...
NCBI chr 3:186,842,710...186,858,463
Ensembl chr 3:186,842,704...186,858,463
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ADIPOR2
adiponectin receptor 2
increases expression
ISO
tributyltin results in increased expression of ADIPOR2 mRNA
CTD
PMID:23428407
NCBI chr12:1,691,070...1,788,674
Ensembl chr12:1,688,574...1,788,674
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ADRB2
adrenoceptor beta 2
decreases expression
EXP
tributyltin results in decreased expression of ADRB2 mRNA
CTD
PMID:28011154
NCBI chr 5:148,826,611...148,828,623
Ensembl chr 5:148,826,611...148,828,623
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AFP
alpha fetoprotein
increases expression
ISO
tributyltin results in increased expression of AFP mRNA
CTD
PMID:31939706
NCBI chr 4:73,436,221...73,456,174
Ensembl chr 4:73,431,138...73,456,174
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AGPAT2
1-acylglycerol-3-phosphate O-acyltransferase 2
increases expression
ISO
tributyltin results in increased expression of AGPAT2 mRNA
CTD
PMID:23428407
NCBI chr 9:136,673,143...136,687,457
Ensembl chr 9:136,673,143...136,687,457
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AGPAT3
1-acylglycerol-3-phosphate O-acyltransferase 3
increases expression
ISO
tributyltin results in increased expression of AGPAT3 mRNA
CTD
PMID:23428407
NCBI chr21:43,865,223...43,987,592
Ensembl chr21:43,865,223...43,987,592
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AGT
angiotensinogen
increases expression decreases expression
ISO
tributyltin results in increased expression of AGT mRNA tributyltin results in decreased expression of AGT protein modified form
CTD
PMID:23428407 PMID:30172001
NCBI chr 1:230,702,523...230,745,583
Ensembl chr 1:230,690,776...230,745,576
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AGTR1
angiotensin II receptor type 1
increases expression
ISO
tributyltin results in increased expression of AGTR1A protein
CTD
PMID:30172001
NCBI chr 3:148,697,903...148,743,003
Ensembl chr 3:148,697,784...148,743,008
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AGTR2
angiotensin II receptor type 2
decreases expression
ISO
tributyltin results in decreased expression of AGTR2 protein
CTD
PMID:30172001
NCBI chr X:116,170,744...116,174,974
Ensembl chr X:116,170,744...116,174,974
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AHNAK
AHNAK nucleoprotein
increases expression
ISO
tributyltin results in increased expression of AHNAK mRNA
CTD
PMID:21683754
NCBI chr11:62,433,544...62,546,806
Ensembl chr11:62,433,542...62,556,235
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AHR
aryl hydrocarbon receptor
decreases expression
ISO
tributyltin results in decreased expression of AHR mRNA
CTD
PMID:22749964
NCBI chr 7:17,298,652...17,346,147
Ensembl chr 7:16,916,359...17,346,152
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AHRR
aryl hydrocarbon receptor repressor
multiple interactions decreases expression
ISO
tributyltin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of AHRR mRNA] tributyltin results in decreased expression of AHRR mRNA
CTD
PMID:22749964
NCBI chr 5:321,714...438,285
Ensembl chr 5:321,714...438,291
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AIF1
allograft inflammatory factor 1
multiple interactions decreases expression
ISO
Phycocyanin inhibits the reaction [tributyltin results in decreased expression of AIF1 protein]
CTD
PMID:26079211
NCBI chr 6:31,615,234...31,617,015
Ensembl chr 6:31,615,217...31,617,021
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AIFM2
AIF family member 2
increases expression
ISO
tributyltin results in increased expression of AIFM2 mRNA
CTD
PMID:24848799
NCBI chr10:70,112,271...70,132,825
Ensembl chr10:70,098,223...70,132,934
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AKR1B1
aldo-keto reductase family 1 member B
increases expression
ISO
tributyltin results in increased expression of AKR1B1 mRNA
CTD
PMID:24848799
NCBI chr 7:134,442,350...134,459,239
Ensembl chr 7:134,442,356...134,459,284
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AKR1B15
aldo-keto reductase family 1 member B15
increases expression
ISO
tributyltin results in increased expression of AKR1B7 mRNA
CTD
PMID:31939706
NCBI chr 7:134,549,110...134,579,869
Ensembl chr 7:134,549,110...134,579,875
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AKT1
AKT serine/threonine kinase 1
increases expression increases phosphorylation
ISO
tributyltin results in increased expression of AKT1 protein tributyltin results in increased phosphorylation of AKT1 protein
CTD
PMID:30172001
NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,759
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AKT3
AKT serine/threonine kinase 3
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of AKT3 mRNA
CTD
PMID:31129395
NCBI chr 1:243,488,233...243,851,079
Ensembl chr 1:243,488,233...243,851,079
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ALAS1
5'-aminolevulinate synthase 1
increases expression
ISO
tributyltin results in increased expression of ALAS1 mRNA
CTD
PMID:31939706
NCBI chr 3:52,198,083...52,214,327
Ensembl chr 3:52,198,086...52,214,327
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ALDH18A1
aldehyde dehydrogenase 18 family member A1
increases expression
ISO
tributyltin results in increased expression of ALDH18A1 mRNA
CTD
PMID:31939706
NCBI chr10:95,605,941...95,656,711
Ensembl chr10:95,605,941...95,656,711
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ALDH1A1
aldehyde dehydrogenase 1 family member A1
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of ALDH1A1 mRNA; [bisphenol A co-treated with tributyltin] results in decreased expression of ALDH1A1 protein
CTD
PMID:31129395
NCBI chr 9:72,900,671...72,953,053
Ensembl chr 9:72,900,671...73,080,442
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ALDH8A1
aldehyde dehydrogenase 8 family member A1
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of ALDH8A1 mRNA
CTD
PMID:31129395
NCBI chr 6:134,917,393...134,950,101
Ensembl chr 6:134,917,393...134,950,115
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ALG8
ALG8 alpha-1,3-glucosyltransferase
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of ALG8 mRNA
CTD
PMID:31129395
NCBI chr11:78,100,946...78,139,626
Ensembl chr11:78,095,244...78,139,660
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ALOX5AP
arachidonate 5-lipoxygenase activating protein
decreases expression multiple interactions
ISO
tributyltin results in decreased expression of ALOX5AP mRNA [bisphenol A co-treated with tributyltin] results in decreased expression of ALOX5AP mRNA
CTD
PMID:31129395
NCBI chr13:30,713,485...30,764,426
Ensembl chr13:30,713,478...30,764,426
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ALPL
alkaline phosphatase, biomineralization associated
multiple interactions decreases expression
ISO
tributyltin promotes the reaction [Tetrachlorodibenzodioxin results in decreased expression of ALPL mRNA] tributyltin results in decreased expression of ALPL mRNA; tributyltin results in decreased expression of ALPL protein
CTD
PMID:22749964 PMID:23322813 PMID:25777084
NCBI chr 1:21,508,984...21,578,410
Ensembl chr 1:21,509,397...21,578,410
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ANG
angiogenin
decreases expression
EXP
tributyltin results in decreased expression of ANG mRNA
CTD
PMID:26314263
NCBI chr14:20,684,177...20,694,186
Ensembl chr14:20,684,177...20,698,971
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ANGPT2
angiopoietin 2
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of ANGPT2 mRNA
CTD
PMID:31129395
NCBI chr 8:6,499,632...6,563,245
Ensembl chr 8:6,499,632...6,563,409
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ANGPTL4
angiopoietin like 4
increases expression
ISO
tributyltin results in increased expression of ANGPTL4 mRNA
CTD
PMID:21622945 PMID:21683754 PMID:23428407
NCBI chr19:8,364,155...8,374,370
Ensembl chr19:8,363,289...8,374,370
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ANKRD27
ankyrin repeat domain 27
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of ANKRD27 mRNA
CTD
PMID:31129395
NCBI chr19:32,597,006...32,675,180
Ensembl chr19:32,597,006...32,676,597
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ANKRD37
ankyrin repeat domain 37
increases expression
ISO
tributyltin results in increased expression of ANKRD37 mRNA
CTD
PMID:21683754
NCBI chr 4:185,396,841...185,400,723
Ensembl chr 4:185,396,021...185,400,628
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ANXA4
annexin A4
increases expression
ISO
tributyltin results in increased expression of ANXA4 mRNA
CTD
PMID:21683754
NCBI chr 2:69,643,808...69,827,112
Ensembl chr 2:69,644,425...69,827,112
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ANXA5
annexin A5
multiple interactions decreases expression
EXP
Tretinoin promotes the reaction [tributyltin results in decreased expression of ANXA5 protein]
CTD
PMID:30806631
NCBI chr 4:121,667,946...121,696,980
Ensembl chr 4:121,667,946...121,696,995
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AP1M2
adaptor related protein complex 1 subunit mu 2
increases expression
ISO
tributyltin results in increased expression of AP1M2 mRNA
CTD
PMID:31939706
NCBI chr19:10,572,671...10,587,312
Ensembl chr19:10,572,671...10,587,315
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AP3S2
adaptor related protein complex 3 subunit sigma 2
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of AP3S2 mRNA
CTD
PMID:31129395
NCBI chr15:89,830,599...89,893,994
Ensembl chr15:89,830,599...89,894,638
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APOC1
apolipoprotein C1
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of APOC1 mRNA
CTD
PMID:31129395
NCBI chr19:44,914,325...44,919,346
Ensembl chr19:44,914,247...44,919,349
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APOE
apolipoprotein E
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of APOE mRNA
CTD
PMID:31129395
NCBI chr19:44,905,796...44,909,393
Ensembl chr19:44,905,791...44,909,393
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APOL2
apolipoprotein L2
multiple interactions decreases expression
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of APOL2 mRNA tributyltin results in decreased expression of APOL2 mRNA
CTD
PMID:31129395
NCBI chr22:36,226,209...36,239,954
Ensembl chr22:36,226,209...36,239,954
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AR
androgen receptor
multiple interactions
EXP
tributyltin inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]
CTD
PMID:33049310
NCBI chr X:67,544,021...67,730,619
Ensembl chr X:67,544,021...67,730,619
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ARHGAP36
Rho GTPase activating protein 36
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of ARHGAP36 mRNA
CTD
PMID:31129395
NCBI chr X:131,058,346...131,089,885
Ensembl chr X:131,058,346...131,089,885
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ARHGEF16
Rho guanine nucleotide exchange factor 16
increases expression
ISO
tributyltin results in increased expression of ARHGEF16 mRNA
CTD
PMID:31939706
NCBI chr 1:3,454,665...3,481,113
Ensembl chr 1:3,454,665...3,481,113
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ART3
ADP-ribosyltransferase 3 (inactive)
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of ART3 mRNA
CTD
PMID:31129395
NCBI chr 4:76,011,190...76,112,786
Ensembl chr 4:76,011,184...76,114,048
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ASB10
ankyrin repeat and SOCS box containing 10
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of ASB10 mRNA
CTD
PMID:31129395
NCBI chr 7:151,175,698...151,187,792
Ensembl chr 7:151,175,698...151,187,832
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ASCL1
achaete-scute family bHLH transcription factor 1
multiple interactions
EXP
[tributyltin co-treated with LHB protein] results in increased expression of ASCL1 mRNA
CTD
PMID:38630605
NCBI chr12:102,957,674...102,960,513
Ensembl chr12:102,957,674...102,960,513
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ASCL2
achaete-scute family bHLH transcription factor 2
affects expression
ISO
tributyltin affects the expression of ASCL2 mRNA
CTD
PMID:33720505
NCBI chr11:2,268,498...2,270,588
Ensembl chr11:2,268,498...2,270,588
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ASGR1
asialoglycoprotein receptor 1
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of ASGR1 mRNA
CTD
PMID:31129395
NCBI chr17:7,173,431...7,179,370
Ensembl chr17:7,173,431...7,179,564
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ASNS
asparagine synthetase (glutamine-hydrolyzing)
increases expression
ISO
tributyltin results in increased expression of ASNS mRNA
CTD
PMID:31939706
NCBI chr 7:97,851,677...97,928,441
Ensembl chr 7:97,851,677...97,872,542
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ASPA
aspartoacylase
increases expression
ISO
tributyltin results in increased expression of ASPA mRNA
CTD
PMID:24848799
NCBI chr17:3,474,110...3,503,405
Ensembl chr17:3,472,374...3,503,405
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ASPN
asporin
increases expression
ISO
tributyltin results in increased expression of ASPN mRNA
CTD
PMID:21683754
NCBI chr 9:92,456,205...92,482,506
Ensembl chr 9:92,456,205...92,482,506
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ASTL
astacin like metalloendopeptidase
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of ASTL mRNA
CTD
PMID:31129395
NCBI chr 2:96,122,818...96,138,564
Ensembl chr 2:96,122,818...96,138,502
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ATAD5
ATPase family AAA domain containing 5
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of ATAD5 mRNA
CTD
PMID:31129395
NCBI chr17:30,831,966...30,895,869
Ensembl chr17:30,831,966...30,895,869
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ATF2
activating transcription factor 2
increases phosphorylation
EXP
tributyltin results in increased phosphorylation of ATF2 protein
CTD
PMID:21626652
NCBI chr 2:175,072,259...175,168,203
Ensembl chr 2:175,072,250...175,168,382
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ATF3
activating transcription factor 3
increases expression
ISO
tributyltin results in increased expression of ATF3 mRNA
CTD
PMID:21683754
NCBI chr 1:212,565,407...212,620,777
Ensembl chr 1:212,565,334...212,620,777
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ATF6
activating transcription factor 6
increases cleavage
EXP
tributyltin results in increased cleavage of ATF6 protein
CTD
PMID:23743301
NCBI chr 1:161,766,320...161,964,070
Ensembl chr 1:161,766,298...161,977,574
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ATM
ATM serine/threonine kinase
multiple interactions increases phosphorylation
EXP ISO
2-(2,6-dimethylmorpholin-4-yl)-N-(5-(6-morpholin-4-yl-4-oxo-4H-pyran-2-yl)-9H-thioxanthen-2-yl)acetamide inhibits the reaction [tributyltin results in increased phosphorylation of ATM protein]
CTD
PMID:36319700
NCBI chr11:108,223,067...108,369,102
Ensembl chr11:108,222,804...108,369,102
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ATP11A
ATPase phospholipid transporting 11A
decreases expression
ISO
tributyltin results in decreased expression of ATP11A mRNA
CTD
PMID:31939706
NCBI chr13:112,690,038...112,887,168
Ensembl chr13:112,690,038...112,887,168
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ATP2A2
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2
decreases expression
EXP
tributyltin results in decreased expression of ATP2A2 protein
CTD
PMID:23743301
NCBI chr12:110,280,616...110,351,093
Ensembl chr12:110,280,756...110,351,093
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AZU1
azurocidin 1
decreases expression
EXP
tributyltin results in decreased expression of AZU1 mRNA
CTD
PMID:26314263
NCBI chr19:827,837...832,018
Ensembl chr19:825,097...832,018
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B3GALNT1
beta-1,3-N-acetylgalactosaminyltransferase 1 (Globoside blood group)
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of B3GALNT1 mRNA
CTD
PMID:31129395
NCBI chr 3:161,083,883...161,105,349
Ensembl chr 3:161,083,883...161,105,411
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B3GALT1
beta-1,3-galactosyltransferase 1
decreases expression
ISO
tributyltin results in decreased expression of B3GALT1 mRNA
CTD
PMID:31939706
NCBI chr 2:167,293,001...167,874,045
Ensembl chr 2:167,293,001...167,874,045
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B3GNT3
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
increases expression
ISO
tributyltin results in increased expression of B3GNT3 mRNA
CTD
PMID:31939706
NCBI chr19:17,794,791...17,813,576
Ensembl chr19:17,794,828...17,813,576
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BAD
BCL2 associated agonist of cell death
multiple interactions
ISO
PRKCD gene mutant form inhibits the reaction [tributyltin results in decreased expression of BAD protein modified form]
CTD
PMID:25895139
NCBI chr11:64,269,828...64,284,704
Ensembl chr11:64,269,830...64,284,704
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BAG3
BAG cochaperone 3
affects expression
EXP
tributyltin affects the expression of BAG3 mRNA
CTD
PMID:27678064
NCBI chr10:119,651,380...119,677,819
Ensembl chr10:119,651,380...119,677,819
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BAIAP2L1
BAR/IMD domain containing adaptor protein 2 like 1
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of BAIAP2L1 mRNA
CTD
PMID:31129395
NCBI chr 7:98,291,650...98,401,090
Ensembl chr 7:98,291,650...98,401,090
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BAX
BCL2 associated X, apoptosis regulator
affects expression multiple interactions increases expression
ISO
tributyltin affects the expression of BAX protein PRKCD gene mutant form inhibits the reaction [tributyltin results in increased expression of BAX protein] Phycocyanin inhibits the reaction [tributyltin results in increased expression of BAX protein]
CTD
PMID:22223438 PMID:23743147 PMID:25895139 PMID:26079211 PMID:28707438
NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798
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BAZ2A
bromodomain adjacent to zinc finger domain 2A
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of BAZ2A mRNA
CTD
PMID:31129395
NCBI chr12:56,595,596...56,638,318
Ensembl chr12:56,595,596...56,636,816
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BBIP1
BBSome interacting protein 1
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of BBIP1 mRNA
CTD
PMID:31129395
NCBI chr10:110,898,730...110,919,366
Ensembl chr10:110,898,730...110,919,201
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BBS2
Bardet-Biedl syndrome 2
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of BBS2 mRNA
CTD
PMID:31129395
NCBI chr16:56,470,403...56,520,024
Ensembl chr16:56,465,640...56,582,667
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BCAT1
branched chain amino acid transaminase 1
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of BCAT1 mRNA
CTD
PMID:31129395
NCBI chr12:24,810,024...24,949,340
Ensembl chr12:24,810,024...24,949,101
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BCL2
BCL2 apoptosis regulator
affects expression decreases expression multiple interactions
ISO EXP
tributyltin affects the expression of BCL2 protein tributyltin results in decreased expression of BCL2 protein PRKCD gene mutant form inhibits the reaction [tributyltin results in decreased expression of BCL2 protein] Acetylcysteine inhibits the reaction [tributyltin results in decreased expression of BCL2 protein]
CTD
PMID:22223438 PMID:23743147 PMID:25743928 PMID:25895139 PMID:26079211 PMID:28707438 PMID:33720505 More...
NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128
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BCL2L1
BCL2 like 1
multiple interactions
ISO
PRKCD gene mutant form inhibits the reaction [tributyltin results in decreased expression of BCL2L1 protein]
CTD
PMID:25895139
NCBI chr20:31,664,452...31,723,963
Ensembl chr20:31,664,452...31,723,989
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BDKRB1
bradykinin receptor B1
decreases expression
ISO
tributyltin results in decreased expression of BDKRB1 mRNA
CTD
PMID:31129395
NCBI chr14:96,256,210...96,264,763
Ensembl chr14:96,256,210...96,268,967
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BECN1
beclin 1
decreases expression
ISO
tributyltin results in decreased expression of BECN1 protein
CTD
PMID:26079211
NCBI chr17:42,810,132...42,824,282
Ensembl chr17:42,810,134...42,833,350
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BGLAP
bone gamma-carboxyglutamate protein
multiple interactions increases expression
ISO EXP
tributyltin promotes the reaction [Tetrachlorodibenzodioxin results in decreased expression of BGLAP mRNA] tributyltin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA] tributyltin results in increased expression of BGLAP mRNA
CTD
PMID:22749964 PMID:25932594
NCBI chr 1:156,242,184...156,243,317
Ensembl chr 1:156,242,184...156,243,317
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BGN
biglycan
increases expression
ISO
tributyltin results in increased expression of BGN mRNA
CTD
PMID:21683754
NCBI chr X:153,494,980...153,509,546
Ensembl chr X:153,494,980...153,509,546
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BHLHE41
basic helix-loop-helix family member e41
increases expression
ISO
tributyltin results in increased expression of BHLHE41 mRNA
CTD
PMID:31939706
NCBI chr12:26,120,030...26,125,037
Ensembl chr12:26,120,030...26,125,037
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BICC1
BicC family RNA binding protein 1
decreases expression
ISO
tributyltin results in decreased expression of BICC1 mRNA
CTD
PMID:31129395
NCBI chr10:58,512,220...58,831,435
Ensembl chr10:58,512,872...58,831,435
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BIRC2
baculoviral IAP repeat containing 2
decreases expression
EXP
tributyltin results in decreased expression of BIRC2 mRNA
CTD
PMID:27678064
NCBI chr11:102,347,214...102,378,670
Ensembl chr11:102,347,211...102,378,670
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BIRC3
baculoviral IAP repeat containing 3
decreases expression
EXP
tributyltin results in decreased expression of BIRC3 mRNA
CTD
PMID:27678064
NCBI chr11:102,317,484...102,339,403
Ensembl chr11:102,317,484...102,339,403
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BMAL1
basic helix-loop-helix ARNT like 1
decreases expression
ISO
tributyltin results in decreased expression of BMAL1 mRNA
CTD
PMID:31939706
NCBI chr11:13,276,652...13,387,266
Ensembl chr11:13,276,652...13,387,266
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BMF
Bcl2 modifying factor
increases expression
ISO
tributyltin results in increased expression of BMF mRNA
CTD
PMID:31939706
NCBI chr15:40,087,890...40,108,879
Ensembl chr15:40,087,890...40,108,892
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BMPR1B
bone morphogenetic protein receptor type 1B
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of BMPR1B mRNA
CTD
PMID:31129395
NCBI chr 4:94,757,955...95,158,450
Ensembl chr 4:94,757,955...95,158,448
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BNIP5
BCL2 interacting protein 5
increases expression
ISO
tributyltin results in increased expression of BNIP5 mRNA
CTD
PMID:31939706
NCBI chr 6:36,315,761...36,336,888
Ensembl chr 6:36,315,761...36,336,888
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BOD1L1
biorientation of chromosomes in cell division 1 like 1
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of BOD1L1 mRNA
CTD
PMID:31129395
NCBI chr 4:13,568,738...13,627,725
Ensembl chr 4:13,568,738...13,627,725
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BRD9
bromodomain containing 9
increases expression
ISO
tributyltin results in increased expression of BRD9 mRNA
CTD
PMID:31129395
NCBI chr 5:863,741...892,801
Ensembl chr 5:850,291...892,801
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BSN
bassoon presynaptic cytomatrix protein
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of BSN mRNA
CTD
PMID:31129395
NCBI chr 3:49,554,477...49,673,130
Ensembl chr 3:49,554,477...49,671,549
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BSPRY
B-box and SPRY domain containing
increases expression
ISO
tributyltin results in increased expression of BSPRY mRNA
CTD
PMID:31939706
NCBI chr 9:113,349,541...113,371,222
Ensembl chr 9:113,349,541...113,371,233
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BTG2
BTG anti-proliferation factor 2
decreases expression
ISO
tributyltin results in decreased expression of BTG2 mRNA
CTD
PMID:31939706
NCBI chr 1:203,305,519...203,309,602
Ensembl chr 1:203,305,491...203,309,602
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C17orf58
chromosome 17 open reading frame 58
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of C10H17ORF58 mRNA
CTD
PMID:31129395
NCBI chr17:67,991,099...67,996,469
Ensembl chr17:67,991,099...67,996,469
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C1GALT1
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
decreases expression
ISO
tributyltin results in decreased expression of C1GALT1 mRNA
CTD
PMID:31129395
NCBI chr 7:7,157,377...7,248,616
Ensembl chr 7:7,156,934...7,248,616
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C1RL
complement C1r subcomponent like
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of C1RL mRNA
CTD
PMID:31129395
NCBI chr12:7,094,554...7,109,214
Ensembl chr12:7,089,587...7,109,238
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C5
complement C5
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of C5 mRNA
CTD
PMID:31129395
NCBI chr 9:120,952,335...121,074,865
Ensembl chr 9:120,932,987...121,075,195
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C8G
complement C8 gamma chain
affects binding multiple interactions
ISO
tributyltin binds to C8G protein tributyltin inhibits the reaction [triphenyltin binds to C8G protein]
CTD
PMID:32879257
NCBI chr 9:136,945,243...136,946,975
Ensembl chr 9:136,945,185...136,946,975
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CA13
carbonic anhydrase 13
increases expression
ISO
tributyltin results in increased expression of CAR13 mRNA
CTD
PMID:31939706
NCBI chr 8:85,245,458...85,284,073
Ensembl chr 8:85,220,587...85,284,073
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CA14
carbonic anhydrase 14
increases expression
ISO
tributyltin results in increased expression of CAR14 mRNA
CTD
PMID:21683754
NCBI chr 1:150,257,774...150,265,078
Ensembl chr 1:150,257,251...150,265,078
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CA9
carbonic anhydrase 9
increases expression
ISO
tributyltin results in increased expression of CAR9 mRNA
CTD
PMID:21683754
NCBI chr 9:35,673,928...35,681,159
Ensembl chr 9:35,673,928...35,681,159
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CACNA1H
calcium voltage-gated channel subunit alpha1 H
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of CACNA1H mRNA
CTD
PMID:31129395
NCBI chr16:1,153,106...1,221,768
Ensembl chr16:1,153,103...1,224,169
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CADPS2
calcium dependent secretion activator 2
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of CADPS2 mRNA
CTD
PMID:31129395
NCBI chr 7:122,318,411...122,886,460
Ensembl chr 7:122,318,411...122,886,759
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CALM1
calmodulin 1
multiple interactions
ISO
CALM1 protein inhibits the reaction [tributyltin results in decreased activity of NOS1 protein]; tributyltin inhibits the reaction [CALM1 protein binds to NOS1 protein]
CTD
PMID:15464999
NCBI chr14:90,396,502...90,408,268
Ensembl chr14:90,396,502...90,408,268
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CALML4
calmodulin like 4
increases expression
ISO
tributyltin results in increased expression of CALML4 mRNA
CTD
PMID:31939706
NCBI chr15:68,190,705...68,206,110
Ensembl chr15:68,190,705...68,206,079
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CALR3
calreticulin 3
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of CALR3 mRNA
CTD
PMID:31129395
NCBI chr19:16,479,061...16,496,167
Ensembl chr19:16,479,061...16,496,167
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CAMK2B
calcium/calmodulin dependent protein kinase II beta
increases activity decreases expression multiple interactions
ISO
tributyltin results in increased activity of CAMK2B protein tributyltin results in decreased expression of CAMK2B mRNA [bisphenol A co-treated with tributyltin] results in increased expression of CAMK2B mRNA
CTD
PMID:20810541 PMID:31129395
NCBI chr 7:44,217,154...44,326,013
Ensembl chr 7:44,210,019...44,334,577
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CAMK2D
calcium/calmodulin dependent protein kinase II delta
increases activity
ISO
tributyltin results in increased activity of CAMK2D protein
CTD
PMID:20810541
NCBI chr 4:113,451,032...113,761,738
Ensembl chr 4:113,418,054...113,761,927
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CAMK2G
calcium/calmodulin dependent protein kinase II gamma
increases activity
ISO
tributyltin results in increased activity of CAMK2G protein
CTD
PMID:20810541
NCBI chr10:73,812,501...73,874,555
Ensembl chr10:73,812,501...73,874,591
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CAMTA1
calmodulin binding transcription activator 1
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of CAMTA1 mRNA
CTD
PMID:31129395
NCBI chr 1:6,785,454...7,769,706
Ensembl chr 1:6,785,454...7,769,706
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CAPN12
calpain 12
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of CAPN12 mRNA
CTD
PMID:31129395
NCBI chr19:38,730,192...38,744,693
Ensembl chr19:38,730,187...38,769,904
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CASP12
caspase 12 (gene/pseudogene)
increases expression
ISO
tributyltin results in increased expression of CASP12 protein
CTD
PMID:26079211
NCBI chr11:104,883,286...104,898,460
Ensembl chr11:104,885,718...104,898,670
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CASP3
caspase 3
multiple interactions increases cleavage decreases expression increases activity increases expression
ISO EXP
Acetylcysteine inhibits the reaction [tributyltin results in increased expression of CASP3 protein modified form]; Phycocyanin inhibits the reaction [tributyltin results in increased activity of CASP3 protein]; Phycocyanin inhibits the reaction [tributyltin results in increased expression of CASP3 protein modified form]; SB 203580 inhibits the reaction [tributyltin results in increased expression of CASP3 protein]; tributyltin results in increased expression of and results in increased cleavage of CASP3 protein tributyltin results in increased cleavage of CASP3 protein DFFB protein promotes the reaction [tributyltin results in decreased expression of CASP3 protein] PRKCD gene mutant form inhibits the reaction [tributyltin results in increased expression of CASP3 protein modified form] tributyltin results in increased expression of CASP3 protein; tributyltin results in increased expression of CASP3 protein modified form
CTD
PMID:17341481 PMID:21477642 PMID:21626652 PMID:21683754 PMID:22223438 PMID:23743147 PMID:24055800 PMID:25895139 PMID:26079211 PMID:27521499 PMID:28161095 PMID:28707438 PMID:31401084 PMID:33720505 PMID:36319700 More...
NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062
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CASP6
caspase 6
decreases expression multiple interactions
EXP
tributyltin results in decreased expression of CASP6 protein DFFB protein promotes the reaction [tributyltin results in decreased expression of CASP6 protein]
CTD
PMID:31401084
NCBI chr 4:109,664,388...109,709,767
Ensembl chr 4:109,688,622...109,703,583
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CASP7
caspase 7
increases activity
ISO
tributyltin results in increased activity of CASP7 protein
CTD
PMID:21683754
NCBI chr10:113,679,194...113,730,909
Ensembl chr10:113,679,162...113,730,907
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CASP8
caspase 8
increases expression decreases expression
ISO
tributyltin results in increased expression of CASP8 protein tributyltin results in decreased expression of CASP8 protein
CTD
PMID:23743147 PMID:28707438
NCBI chr 2:201,233,463...201,287,711
Ensembl chr 2:201,233,443...201,361,836
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CASP9
caspase 9
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of CASP9 mRNA
CTD
PMID:31129395
NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534
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CAST
calpastatin
multiple interactions
ISO
CAST protein inhibits the reaction [tributyltin results in increased degradation of MAPT protein]; CAST protein inhibits the reaction [tributyltin results in increased degradation of NEFM protein]; CAST protein inhibits the reaction [tributyltin results in increased degradation of TUBB3 protein]
CTD
PMID:33481012
NCBI chr 5:95,961,429...96,774,683
Ensembl chr 5:96,247,756...96,779,595 Ensembl chr 5:96,247,756...96,779,595
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CASZ1
castor zinc finger 1
increases expression
ISO
tributyltin results in increased expression of CASZ1 mRNA
CTD
PMID:31939706
NCBI chr 1:10,636,604...10,796,646
Ensembl chr 1:10,636,604...10,796,650
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CAT
catalase
multiple interactions decreases activity increases expression
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of CAT mRNA; Acetylcysteine inhibits the reaction [tributyltin results in increased expression of CAT protein] tributyltin results in decreased activity of CAT protein
CTD
PMID:26079211 PMID:26873547 PMID:31129395 PMID:33720505 PMID:34902535
NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
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CBLN1
cerebellin 1 precursor
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of CBLN1 mRNA
CTD
PMID:31129395
NCBI chr16:49,277,917...49,281,838
Ensembl chr16:49,277,917...49,281,838
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CCDC125
coiled-coil domain containing 125
decreases expression
ISO
tributyltin results in decreased expression of CCDC125 mRNA
CTD
PMID:21683754
NCBI chr 5:69,273,039...69,332,801
Ensembl chr 5:69,280,175...69,332,809
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CCDC159
coiled-coil domain containing 159
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of CCDC159 mRNA
CTD
PMID:31129395
NCBI chr19:11,346,519...11,354,944
Ensembl chr19:11,344,684...11,354,944
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CCL2
C-C motif chemokine ligand 2
increases expression
EXP ISO
tributyltin results in increased expression of CCL2 mRNA
CTD
PMID:36319700
NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208
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CCL25
C-C motif chemokine ligand 25
increases expression
ISO
tributyltin results in increased expression of CCL25 mRNA
CTD
PMID:31939706
NCBI chr19:8,052,341...8,062,650
Ensembl chr19:8,052,318...8,062,660
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CCL5
C-C motif chemokine ligand 5
multiple interactions
EXP
[tributyltin co-treated with LHB protein] results in decreased secretion of CCL5 protein
CTD
PMID:38630605
NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793
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CCL7
C-C motif chemokine ligand 7
decreases expression
ISO
tributyltin results in decreased expression of CCL7 mRNA
CTD
PMID:21683754
NCBI chr17:34,270,221...34,272,242
Ensembl chr17:34,270,221...34,272,242
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CCL8
C-C motif chemokine ligand 8
multiple interactions
EXP
[tributyltin co-treated with LHB protein] results in decreased secretion of CCL8 protein
CTD
PMID:38630605
NCBI chr17:34,319,435...34,321,402
Ensembl chr17:34,319,435...34,321,402
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CCNB1
cyclin B1
decreases expression multiple interactions
EXP
tributyltin results in decreased expression of CCNB1 protein dimethyl alpha-ketoglutarate inhibits the reaction [tributyltin results in decreased expression of CCNB1 protein]; IDH3A protein affects the reaction [tributyltin results in decreased expression of CCNB1 protein]
CTD
PMID:26961604
NCBI chr 5:69,167,150...69,178,245
Ensembl chr 5:69,167,135...69,178,245
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CCR1
C-C motif chemokine receptor 1
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of CCR1 mRNA
CTD
PMID:31129395
NCBI chr 3:46,201,711...46,208,313
Ensembl chr 3:46,201,711...46,208,313
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CCR7
C-C motif chemokine receptor 7
increases expression
EXP
tributyltin results in increased expression of CCR7 mRNA
CTD
PMID:19371601
NCBI chr17:40,553,769...40,565,472
Ensembl chr17:40,551,081...40,565,472
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CCT7
chaperonin containing TCP1 subunit 7
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of CCT7 mRNA
CTD
PMID:31129395
NCBI chr 2:73,234,308...73,253,005
Ensembl chr 2:73,233,420...73,253,021
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CD22
CD22 molecule
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of CD22 mRNA
CTD
PMID:31129395
NCBI chr19:35,329,187...35,347,361
Ensembl chr19:35,319,261...35,347,361
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CD300LF
CD300 molecule like family member f
increases expression
ISO
tributyltin results in increased expression of CD300LF mRNA
CTD
PMID:31939706
NCBI chr17:74,694,317...74,712,923
Ensembl chr17:74,694,311...74,712,978
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CD36
CD36 molecule (CD36 blood group)
increases expression
ISO
tributyltin results in increased expression of CD36 mRNA
CTD
PMID:23428407 PMID:24848799
NCBI chr 7:80,602,207...80,679,274
Ensembl chr 7:80,369,575...80,679,277
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CD68
CD68 molecule
increases expression
ISO
tributyltin results in increased expression of CD68 protein
CTD
PMID:25819109
NCBI chr17:7,579,638...7,582,111
Ensembl chr17:7,579,491...7,582,111
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CD83
CD83 molecule
increases expression
ISO
tributyltin results in increased expression of CD83 mRNA
CTD
PMID:21683754
NCBI chr 6:14,117,256...14,136,918
Ensembl chr 6:14,117,256...14,140,682
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CDC14A
cell division cycle 14A
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of CDC14A mRNA
CTD
PMID:31129395
NCBI chr 1:100,345,001...100,520,277
Ensembl chr 1:100,325,629...100,520,277
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CDC25C
cell division cycle 25C
multiple interactions decreases expression
EXP
dimethyl alpha-ketoglutarate inhibits the reaction [tributyltin results in decreased expression of CDC25C protein]; IDH3A protein affects the reaction [tributyltin results in decreased expression of CDC25C protein]
CTD
PMID:26961604
NCBI chr 5:138,285,265...138,338,355
Ensembl chr 5:138,285,269...138,338,355
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CDCA3
cell division cycle associated 3
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of CDCA3 mRNA
CTD
PMID:31129395
NCBI chr12:6,844,798...6,851,286
Ensembl chr12:6,844,793...6,851,292
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CDH9
cadherin 9
decreases expression
ISO
tributyltin results in decreased expression of CDH9 mRNA
CTD
PMID:31129395
NCBI chr 5:26,880,597...27,038,586
Ensembl chr 5:26,880,597...27,121,150
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CDHR2
cadherin related family member 2
increases expression
ISO
tributyltin results in increased expression of CDHR2 mRNA
CTD
PMID:31939706
NCBI chr 5:176,542,511...176,595,974
Ensembl chr 5:176,542,511...176,595,974
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CDIP1
cell death inducing p53 target 1
increases expression
ISO
tributyltin results in increased expression of CDIP1 mRNA
CTD
PMID:31129395
NCBI chr16:4,510,669...4,538,773
Ensembl chr16:4,510,669...4,538,828
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CDK13
cyclin dependent kinase 13
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of CDK13 mRNA
CTD
PMID:31129395
NCBI chr 7:39,950,256...40,099,580
Ensembl chr 7:39,950,121...40,099,580
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CDK5R1
cyclin dependent kinase 5 regulatory subunit 1
decreases expression
EXP
tributyltin results in decreased expression of CDK5R1 mRNA
CTD
PMID:26314263
NCBI chr17:32,486,993...32,491,253
Ensembl chr17:32,486,993...32,491,253
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CDKN1A
cyclin dependent kinase inhibitor 1A
increases expression multiple interactions decreases expression
EXP ISO
tributyltin results in increased expression of CDKN1A mRNA; tributyltin results in increased expression of CDKN1A protein 2-(2,6-dimethylmorpholin-4-yl)-N-(5-(6-morpholin-4-yl-4-oxo-4H-pyran-2-yl)-9H-thioxanthen-2-yl)acetamide inhibits the reaction [tributyltin results in increased expression of CDKN1A protein]; pyrazolanthrone inhibits the reaction [tributyltin results in increased expression of CDKN1A protein] tributyltin results in decreased expression of CDKN1A mRNA
CTD
PMID:28011154 PMID:31939706 PMID:36319700
NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,397
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CDKN1B
cyclin dependent kinase inhibitor 1B
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of CDKN1B mRNA
CTD
PMID:31129395
NCBI chr12:12,717,368...12,722,369
Ensembl chr12:12,685,498...12,722,369
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CDKN2B
cyclin dependent kinase inhibitor 2B
multiple interactions
EXP
2-(2,6-dimethylmorpholin-4-yl)-N-(5-(6-morpholin-4-yl-4-oxo-4H-pyran-2-yl)-9H-thioxanthen-2-yl)acetamide inhibits the reaction [tributyltin results in increased expression of CDKN2B protein]
CTD
PMID:36319700
NCBI chr 9:22,002,903...22,009,313
Ensembl chr 9:22,002,903...22,009,305
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CDR2
cerebellar degeneration related protein 2
increases expression
ISO
tributyltin results in increased expression of CDR2 mRNA
CTD
PMID:31939706
NCBI chr16:22,345,936...22,374,619
Ensembl chr16:22,345,936...22,437,165
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CDYL
chromodomain Y like
increases expression
ISO
tributyltin results in increased expression of CDYL mRNA
CTD
PMID:21683754
NCBI chr 6:4,706,138...4,955,544
Ensembl chr 6:4,706,159...4,955,551
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CEBPA
CCAAT enhancer binding protein alpha
increases expression multiple interactions
ISO EXP
tributyltin results in increased expression of CEBPA mRNA T 0070907 inhibits the reaction [tributyltin results in increased expression of CEBPA mRNA]
CTD
PMID:25932594 PMID:28011154 PMID:29787037
NCBI chr19:33,299,934...33,302,534
Ensembl chr19:33,299,934...33,302,534
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CEBPB
CCAAT enhancer binding protein beta
increases expression
ISO
tributyltin results in increased expression of CEBPB mRNA
CTD
PMID:21683754 PMID:29908848
NCBI chr20:50,190,583...50,192,690
Ensembl chr20:50,190,734...50,192,690
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CELF2
CUGBP Elav-like family member 2
decreases expression
ISO
tributyltin results in decreased expression of CELF2 mRNA
CTD
PMID:21683754
NCBI chr10:10,462,550...11,336,675
Ensembl chr10:10,798,397...11,336,675
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CEP19
centrosomal protein 19
increases expression
ISO
tributyltin results in increased expression of CEP19 mRNA
CTD
PMID:31129395
NCBI chr 3:196,706,277...196,712,250
Ensembl chr 3:196,706,277...196,712,250
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CEP76
centrosomal protein 76
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of CEP76 mRNA
CTD
PMID:31129395
NCBI chr18:12,661,956...12,702,777
Ensembl chr18:12,661,833...12,702,777
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CES1
carboxylesterase 1
increases expression
ISO
tributyltin results in increased expression of CES1D mRNA
CTD
PMID:24848799
NCBI chr16:55,802,851...55,833,096
Ensembl chr16:55,802,851...55,833,337
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CFAP210
cilia and flagella associated protein 210
decreases expression
ISO
tributyltin results in decreased expression of CFAP210 mRNA
CTD
PMID:31129395
NCBI chr 2:169,645,425...169,694,405
Ensembl chr 2:169,645,425...169,694,405
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CFAP53
cilia and flagella associated protein 53
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of CFAP53 mRNA
CTD
PMID:31129395
NCBI chr18:50,227,193...50,266,495
Ensembl chr18:50,227,193...50,266,495
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CFD
complement factor D
increases expression
ISO
tributyltin results in increased expression of CFD mRNA
CTD
PMID:23428407
NCBI chr19:859,664...863,641
Ensembl chr19:859,453...867,884
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CFTR
CF transmembrane conductance regulator
increases expression
ISO
tributyltin results in increased expression of CFTR mRNA
CTD
PMID:31939706
NCBI chr 7:117,480,025...117,668,665
Ensembl chr 7:117,287,120...117,715,971
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CGB3
chorionic gonadotropin subunit beta 3
increases expression increases secretion
EXP
tributyltin results in increased expression of CGB3 mRNA tributyltin results in increased secretion of CGB3 protein
CTD
PMID:15941851 PMID:19497422
NCBI chr19:49,022,869...49,024,333
Ensembl chr19:49,022,869...49,024,333
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CHAC1
ChaC glutathione specific gamma-glutamylcyclotransferase 1
decreases expression
ISO
tributyltin results in decreased expression of CHAC1 mRNA
CTD
PMID:31939706
NCBI chr15:40,953,471...40,956,512
Ensembl chr15:40,952,962...40,956,512
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CHAT
choline O-acetyltransferase
decreases activity
ISO
tributyltin results in decreased activity of CHAT protein
CTD
PMID:9015740
NCBI chr10:49,609,095...49,667,942
Ensembl chr10:49,609,095...49,667,942
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CHD9
chromodomain helicase DNA binding protein 9
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of CHD9 mRNA
CTD
PMID:31129395
NCBI chr16:53,054,991...53,327,497
Ensembl chr16:53,054,991...53,329,150
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CHI3L1
chitinase 3 like 1
increases expression
ISO
tributyltin results in increased expression of CHI3L1 mRNA
CTD
PMID:21683754
NCBI chr 1:203,178,931...203,186,704
Ensembl chr 1:203,178,931...203,186,704
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CHKA
choline kinase alpha
decreases expression
ISO
tributyltin results in decreased expression of CHKA mRNA
CTD
PMID:31939706
NCBI chr11:68,052,859...68,121,388
Ensembl chr11:68,052,859...68,121,444
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CHMP4C
charged multivesicular body protein 4C
increases expression
ISO
tributyltin results in increased expression of CHMP4C mRNA
CTD
PMID:31939706
NCBI chr 8:81,732,448...81,759,515
Ensembl chr 8:81,732,448...81,759,515
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CHP2
calcineurin like EF-hand protein 2
increases expression
ISO
tributyltin results in increased expression of CHP2 mRNA
CTD
PMID:31939706
NCBI chr16:23,755,026...23,758,935
Ensembl chr16:23,755,026...23,758,935
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CIART
circadian associated repressor of transcription
increases expression
ISO
tributyltin results in increased expression of CIART mRNA
CTD
PMID:31939706
NCBI chr 1:150,282,554...150,287,093
Ensembl chr 1:150,282,543...150,287,093
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CIBAR1
CBY1 interacting BAR domain containing 1
increases expression multiple interactions
ISO
tributyltin results in increased expression of CIBAR1 mRNA [bisphenol A co-treated with tributyltin] results in increased expression of CIBAR1 mRNA
CTD
PMID:31129395
NCBI chr 8:93,700,550...93,731,527
Ensembl chr 8:93,698,561...93,731,527
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CIDEA
cell death inducing DFFA like effector a
increases expression
ISO
tributyltin results in increased expression of CIDEA mRNA
CTD
PMID:24848799
NCBI chr18:12,254,361...12,277,595
Ensembl chr18:12,254,361...12,277,595
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CIDEC
cell death inducing DFFA like effector c
increases expression multiple interactions
ISO EXP
tributyltin results in increased expression of CIDEC mRNA T 0070907 inhibits the reaction [tributyltin results in increased expression of CIDEC mRNA]
CTD
PMID:23322813 PMID:29787037
NCBI chr 3:9,866,710...9,880,253
Ensembl chr 3:9,866,711...9,880,255
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CKB
creatine kinase B
increases expression
ISO
tributyltin results in increased expression of CKB mRNA
CTD
PMID:31939706
NCBI chr14:103,519,667...103,522,830
Ensembl chr14:103,519,667...103,522,833
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CLDN14
claudin 14
decreases expression
EXP
tributyltin results in decreased expression of CLDN14 mRNA
CTD
PMID:26314263
NCBI chr21:36,460,621...36,576,569
Ensembl chr21:36,460,621...36,576,569
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CLDN15
claudin 15
increases expression
ISO
tributyltin results in increased expression of CLDN15 mRNA
CTD
PMID:31939706
NCBI chr 7:101,232,094...101,238,820
Ensembl chr 7:101,232,092...101,238,820
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CLDN16
claudin 16
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of CLDN16 mRNA
CTD
PMID:31129395
NCBI chr 3:190,290,361...190,412,138
Ensembl chr 3:190,322,541...190,412,138
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CLDN4
claudin 4
increases expression
ISO
tributyltin results in increased expression of CLDN4 mRNA
CTD
PMID:31939706
NCBI chr 7:73,830,996...73,832,690
Ensembl chr 7:73,799,542...73,832,690
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CLDN5
claudin 5
multiple interactions decreases expression
ISO
Phycocyanin inhibits the reaction [tributyltin results in decreased expression of CLDN5 protein]
CTD
PMID:26079211
NCBI chr22:19,523,024...19,525,337
Ensembl chr22:19,523,024...19,527,545
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CLDN7
claudin 7
increases expression
ISO
tributyltin results in increased expression of CLDN7 mRNA
CTD
PMID:31939706
NCBI chr17:7,259,903...7,263,213
Ensembl chr17:7,259,903...7,263,983
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CLEC2D
C-type lectin domain family 2 member D
increases expression
ISO
tributyltin results in increased expression of CLEC2H mRNA
CTD
PMID:31939706
NCBI chr12:9,669,713...9,699,553
Ensembl chr12:9,664,969...9,699,553
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CLIC4
chloride intracellular channel 4
increases expression
EXP
tributyltin results in increased expression of CLIC4 mRNA
CTD
PMID:26314263
NCBI chr 1:24,745,447...24,844,321
Ensembl chr 1:24,745,382...24,844,321
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CLIC5
chloride intracellular channel 5
increases expression
ISO
tributyltin results in increased expression of CLIC5 mRNA
CTD
PMID:31939706
NCBI chr 6:45,880,827...46,129,819
Ensembl chr 6:45,880,827...46,080,348
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CLPX
caseinolytic mitochondrial matrix peptidase chaperone subunit X
decreases expression
ISO
tributyltin results in decreased expression of CLPX mRNA
CTD
PMID:31939706
NCBI chr15:65,148,219...65,185,342
Ensembl chr15:65,148,219...65,185,342
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CLSTN3
calsyntenin 3
increases expression
ISO
tributyltin results in increased expression of CLSTN3 mRNA
CTD
PMID:24848799
NCBI chr12:7,129,093...7,158,945
Ensembl chr12:7,129,698...7,158,945
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CMAS
cytidine monophosphate N-acetylneuraminic acid synthetase
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of CMAS mRNA
CTD
PMID:31129395
NCBI chr12:22,046,218...22,065,668
Ensembl chr12:22,046,218...22,065,674
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CNP
2',3'-cyclic nucleotide 3' phosphodiesterase
increases expression
ISO
tributyltin results in increased expression of CNP mRNA
CTD
PMID:30027469
NCBI chr17:41,966,795...41,977,740
Ensembl chr17:41,966,763...41,977,740
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COL1A1
collagen type I alpha 1 chain
increases expression
ISO
tributyltin results in increased expression of COL1A1 mRNA
CTD
PMID:21683754
NCBI chr17:50,184,101...50,201,631
Ensembl chr17:50,184,101...50,201,632
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COL1A2
collagen type I alpha 2 chain
increases expression
ISO
tributyltin results in increased expression of COL1A2 mRNA
CTD
PMID:21683754
NCBI chr 7:94,394,895...94,431,227
Ensembl chr 7:94,394,895...94,431,227
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COL2A1
collagen type II alpha 1 chain
decreases expression
ISO
tributyltin results in decreased expression of COL2A1 mRNA
CTD
PMID:24513447
NCBI chr12:47,972,967...48,006,212
Ensembl chr12:47,972,967...48,004,554
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COL6A1
collagen type VI alpha 1 chain
increases expression
ISO
tributyltin results in increased expression of COL6A1 mRNA
CTD
PMID:21683754
NCBI chr21:45,981,770...46,005,048
Ensembl chr21:45,981,770...46,005,050
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COL6A3
collagen type VI alpha 3 chain
increases expression
ISO
tributyltin results in increased expression of COL6A3 mRNA
CTD
PMID:21683754
NCBI chr 2:237,324,018...237,414,164
Ensembl chr 2:237,324,003...237,414,328
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COL7A1
collagen type VII alpha 1 chain
multiple interactions decreases expression
ISO
Tetrachlorodibenzodioxin promotes the reaction [tributyltin results in decreased expression of COL7A1 mRNA]
CTD
PMID:22749964
NCBI chr 3:48,564,073...48,595,329
Ensembl chr 3:48,564,073...48,595,329
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COL9A3
collagen type IX alpha 3 chain
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of COL9A3 mRNA
CTD
PMID:31129395
NCBI chr20:62,816,213...62,841,159
Ensembl chr20:62,816,244...62,841,159
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COMMD9
COMM domain containing 9
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of COMMD9 mRNA
CTD
PMID:31129395
NCBI chr11:36,272,292...36,289,424
Ensembl chr11:36,269,284...36,289,449
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CORO2A
coronin 2A
increases expression
ISO
tributyltin results in increased expression of CORO2A mRNA
CTD
PMID:31939706
NCBI chr 9:98,120,975...98,192,637
Ensembl chr 9:98,120,975...98,192,637
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COX7A1
cytochrome c oxidase subunit 7A1
increases expression
ISO
tributyltin results in increased expression of COX7A1 mRNA
CTD
PMID:24848799 PMID:31939706
NCBI chr19:36,150,922...36,152,447
Ensembl chr19:36,150,922...36,152,449
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COX7A2L
cytochrome c oxidase subunit 7A2 like
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of COX7A2L mRNA
CTD
PMID:31129395
NCBI chr 2:42,335,559...42,368,957
Ensembl chr 2:42,333,546...42,425,088
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COX8BP
cytochrome c oxidase subunit 8B, pseudogene
increases expression
ISO
tributyltin results in increased expression of COX8B mRNA
CTD
PMID:24848799
NCBI chr11:253,417...256,972
Ensembl chr11:253,446...253,558
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CPLX3
complexin 3
increases expression
ISO
tributyltin results in increased expression of CPLX3 mRNA
CTD
PMID:21683754
NCBI chr15:74,826,627...74,831,802
Ensembl chr15:74,826,627...74,831,802
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CPNE4
copine 4
decreases expression
ISO
tributyltin results in decreased expression of CPNE4 mRNA
CTD
PMID:31129395
NCBI chr 3:131,533,569...132,039,606
Ensembl chr 3:131,533,555...132,285,410
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CPT1A
carnitine palmitoyltransferase 1A
increases expression
ISO
tributyltin results in increased expression of CPT1A mRNA
CTD
PMID:23428407
NCBI chr11:68,754,620...68,844,277
Ensembl chr11:68,754,620...68,844,410
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CPT2
carnitine palmitoyltransferase 2
increases expression
ISO
tributyltin results in increased expression of CPT2 mRNA
CTD
PMID:23428407
NCBI chr 1:53,196,824...53,214,197
Ensembl chr 1:53,196,792...53,214,197
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CRABP1
cellular retinoic acid binding protein 1
decreases expression
ISO
tributyltin results in decreased expression of CRABP1 mRNA
CTD
PMID:21683754
NCBI chr15:78,340,353...78,348,225
Ensembl chr15:78,340,353...78,348,225
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CRABP2
cellular retinoic acid binding protein 2
increases expression
ISO
tributyltin results in increased expression of CRABP2 mRNA
CTD
PMID:21683754
NCBI chr 1:156,699,606...156,705,784
Ensembl chr 1:156,699,606...156,705,816
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CRELD1
cysteine rich with EGF like domains 1
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of CRELD1 mRNA
CTD
PMID:31129395
NCBI chr 3:9,933,834...9,945,406
Ensembl chr 3:9,933,793...9,945,413
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CREM
cAMP responsive element modulator
increases expression
ISO
tributyltin results in increased expression of CREM mRNA
CTD
PMID:31129395
NCBI chr10:35,126,846...35,212,958
Ensembl chr10:35,126,791...35,212,958
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CRIP1
cysteine rich protein 1
increases expression
ISO
tributyltin results in increased expression of CRIP1 mRNA
CTD
PMID:31939706
NCBI chr14:105,486,886...105,488,947
Ensembl chr14:105,486,317...105,488,947
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CRLF1
cytokine receptor like factor 1
increases expression
ISO
tributyltin results in increased expression of CRLF1 mRNA
CTD
PMID:21683754
NCBI chr19:18,593,237...18,606,799
Ensembl chr19:18,572,220...18,607,741
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CRTAC1
cartilage acidic protein 1
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of CRTAC1 mRNA
CTD
PMID:31129395
NCBI chr10:97,865,000...98,030,621
Ensembl chr10:97,865,000...98,030,828
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CSF3
colony stimulating factor 3
multiple interactions increases expression
ISO
Tetrachlorodibenzodioxin promotes the reaction [tributyltin results in increased expression of CSF3 mRNA]
CTD
PMID:22749964
NCBI chr17:40,015,440...40,017,813
Ensembl chr17:40,015,361...40,017,813
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CSTF1
cleavage stimulation factor subunit 1
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of CSTF1 mRNA
CTD
PMID:31129395
NCBI chr20:56,392,379...56,406,362
Ensembl chr20:56,392,371...56,406,362
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CTNNA1
catenin alpha 1
increases expression
EXP
tributyltin results in increased expression of CTNNA1 mRNA
CTD
PMID:26314263
NCBI chr 5:138,753,425...138,935,034
Ensembl chr 5:138,610,967...138,935,034
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CTNNB1
catenin beta 1
increases expression
EXP
tributyltin results in increased expression of CTNNB1 mRNA
CTD
PMID:26314263
NCBI chr 3:41,199,505...41,240,443
Ensembl chr 3:41,194,741...41,260,096
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CTSK
cathepsin K
multiple interactions decreases expression
ISO
Tetrachlorodibenzodioxin inhibits the reaction [tributyltin results in decreased expression of CTSK mRNA]
CTD
PMID:22749964
NCBI chr 1:150,796,208...150,808,260
Ensembl chr 1:150,794,880...150,809,577
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CX3CL1
C-X3-C motif chemokine ligand 1
increases expression
ISO
tributyltin results in increased expression of CX3CL1 mRNA
CTD
PMID:31939706
NCBI chr16:57,372,490...57,385,044
Ensembl chr16:57,372,477...57,385,044
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CXCL1
C-X-C motif chemokine ligand 1
decreases expression
ISO
tributyltin results in decreased expression of CXCL1 mRNA
CTD
PMID:31939706
NCBI chr 4:73,869,393...73,871,308
Ensembl chr 4:73,869,393...73,871,308
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CXCL13
C-X-C motif chemokine ligand 13
multiple interactions
EXP
[tributyltin co-treated with LHB protein] results in decreased secretion of CXCL13 protein
CTD
PMID:38630605
NCBI chr 4:77,511,753...77,611,834
Ensembl chr 4:77,511,753...77,611,834
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CXCL14
C-X-C motif chemokine ligand 14
increases expression
ISO
tributyltin results in increased expression of CXCL14 mRNA
CTD
PMID:31939706
NCBI chr 5:135,570,679...135,578,991
Ensembl chr 5:135,570,679...135,579,279
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CXCL8
C-X-C motif chemokine ligand 8
decreases expression
EXP
tributyltin results in decreased expression of CXCL8 mRNA
CTD
PMID:26314263
NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716
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CXCR2
C-X-C motif chemokine receptor 2
decreases expression
ISO
tributyltin results in decreased expression of CXCR2 mRNA
CTD
PMID:31939706
NCBI chr 2:218,125,294...218,137,251
Ensembl chr 2:218,125,289...218,137,251
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CXCR4
C-X-C motif chemokine receptor 4
increases expression
EXP
tributyltin results in increased expression of CXCR4 mRNA
CTD
PMID:19371601 PMID:26314263
NCBI chr 2:136,114,349...136,118,149
Ensembl chr 2:136,114,349...136,119,177
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CYB5A
cytochrome b5 type A
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of CYB5A mRNA
CTD
PMID:31129395
NCBI chr18:74,250,846...74,291,963
Ensembl chr18:74,250,846...74,291,973
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CYBB
cytochrome b-245 beta chain
increases expression
ISO
tributyltin results in increased expression of CYBB protein
CTD
PMID:26873547
NCBI chr X:37,780,059...37,813,461
Ensembl chr X:37,780,018...37,813,461
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CYCS
cytochrome c, somatic
increases expression
ISO
tributyltin results in increased expression of CYCS mRNA
CTD
PMID:24848799
NCBI chr 7:25,118,656...25,125,260
Ensembl chr 7:25,118,656...25,125,260
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CYP11A1
cytochrome P450 family 11 subfamily A member 1
increases expression
ISO
tributyltin results in increased expression of CYP11A1 protein
CTD
PMID:29908848
NCBI chr15:74,337,762...74,367,646
Ensembl chr15:74,337,759...74,367,646
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CYP11B1
cytochrome P450 family 11 subfamily B member 1
multiple interactions decreases expression
EXP
[Tetrachlorodibenzodioxin co-treated with 3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with perfluorooctane sulfonic acid co-treated with hexabromocyclododecane co-treated with 2,2',4,4'-tetrabromodiphenyl ether co-treated with tributyltin co-treated with methylmercuric chloride] results in increased expression of CYP11B1 mRNA tributyltin results in decreased expression of CYP11B1 mRNA
CTD
PMID:25765474 PMID:29549738
NCBI chr 8:142,872,357...142,879,825
Ensembl chr 8:142,872,356...142,879,846
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CYP11B2
cytochrome P450 family 11 subfamily B member 2
multiple interactions increases expression
EXP
[Tetrachlorodibenzodioxin co-treated with 3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with perfluorooctane sulfonic acid co-treated with hexabromocyclododecane co-treated with 2,2',4,4'-tetrabromodiphenyl ether co-treated with tributyltin co-treated with methylmercuric chloride] results in increased expression of CYP11B2 mRNA tributyltin results in increased expression of CYP11B2 mRNA
CTD
PMID:25765474 PMID:29549738
NCBI chr 8:142,910,559...142,917,843
Ensembl chr 8:142,910,559...142,917,843
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CYP17A1
cytochrome P450 family 17 subfamily A member 1
decreases expression
ISO
tributyltin results in decreased expression of CYP17A1 mRNA; tributyltin results in decreased expression of CYP17A1 protein
CTD
PMID:35430282
NCBI chr10:102,830,531...102,837,413
Ensembl chr10:102,830,531...102,837,472
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CYP19A1
cytochrome P450 family 19 subfamily A member 1
multiple interactions increases expression decreases activity increases activity decreases expression
EXP ISO
[Tetrachlorodibenzodioxin co-treated with 3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with perfluorooctane sulfonic acid co-treated with hexabromocyclododecane co-treated with 2,2',4,4'-tetrabromodiphenyl ether co-treated with tributyltin co-treated with methylmercuric chloride] results in increased expression of CYP19A1 mRNA; [tributyltin binds to and results in increased activity of RXRA protein] which results in increased expression of CYP19A1 protein; [tributyltin co-treated with Testosterone] results in increased expression of CYP19A1 mRNA; Finasteride promotes the reaction [[tributyltin co-treated with Testosterone] results in increased expression of CYP19A1 mRNA]; tributyltin inhibits the reaction [CYP19A1 protein affects the metabolism of Testosterone]; tributyltin inhibits the reaction [CYP19A1 protein binds to and results in increased metabolism of Androstenedione]; tributyltin promotes the reaction [[Finasteride co-treated with Testosterone] results in increased expression of CYP19A1 mRNA] tributyltin results in increased expression of CYP19A1 protein [bisphenol A co-treated with tributyltin] results in increased expression of CYP19A1 protein tributyltin results in decreased activity of CYP19A1 protein tributyltin results in increased activity of CYP19A1 protein tributyltin results in increased expression of CYP19A1 mRNA; tributyltin results in increased expression of CYP19A1 protein tributyltin results in decreased expression of CYP19A1 mRNA
CTD
PMID:11522339 PMID:11751016 PMID:15941851 PMID:16996190 PMID:18310892 PMID:23523586 PMID:25765474 PMID:29549738 PMID:29908848 PMID:31129395 More...
NCBI chr15:51,208,057...51,338,596
Ensembl chr15:51,208,057...51,338,601
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CYP1A1
cytochrome P450 family 1 subfamily A member 1
multiple interactions
EXP
[Tetrachlorodibenzodioxin co-treated with 3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with perfluorooctane sulfonic acid co-treated with hexabromocyclododecane co-treated with 2,2',4,4'-tetrabromodiphenyl ether co-treated with tributyltin co-treated with methylmercuric chloride] results in increased expression of CYP1A1 mRNA
CTD
PMID:25765474
NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536
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CYP21A2
cytochrome P450 family 21 subfamily A member 2
decreases expression
EXP
tributyltin results in decreased expression of CYP21A2 mRNA
CTD
PMID:29549738
NCBI chr 6:32,038,415...32,041,644
Ensembl chr 6:32,038,327...32,041,644
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CYP26A1
cytochrome P450 family 26 subfamily A member 1
increases expression
ISO
tributyltin results in increased expression of CYP26A1 mRNA
CTD
PMID:31939706
NCBI chr10:93,073,475...93,077,885
Ensembl chr10:93,073,475...93,077,885
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CYP2S1
cytochrome P450 family 2 subfamily S member 1
increases expression
ISO
tributyltin results in increased expression of CYP2S1 mRNA
CTD
PMID:31939706
NCBI chr19:41,193,219...41,207,539
Ensembl chr19:41,193,210...41,207,539
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CYP7A1
cytochrome P450 family 7 subfamily A member 1
increases expression
ISO
tributyltin results in increased expression of CYP7A1 mRNA
CTD
PMID:31939706
NCBI chr 8:58,490,178...58,500,163
Ensembl chr 8:58,490,178...58,500,163
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CYSLTR2
cysteinyl leukotriene receptor 2
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of CYSLTR2 mRNA
CTD
PMID:31129395
NCBI chr13:48,653,929...48,711,226
Ensembl chr13:48,653,711...48,711,226
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DBI
diazepam binding inhibitor, acyl-CoA binding protein
increases expression
ISO
tributyltin results in increased expression of DBI mRNA
CTD
PMID:23428407
NCBI chr 2:119,366,977...119,372,543
Ensembl chr 2:119,366,924...119,372,550
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DBP
D-box binding PAR bZIP transcription factor
increases expression
ISO
tributyltin results in increased expression of DBP mRNA
CTD
PMID:31939706
NCBI chr19:48,630,030...48,637,379
Ensembl chr19:48,630,030...48,637,379
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DCLK1
doublecortin like kinase 1
increases expression
ISO
tributyltin results in increased expression of DCLK1 mRNA
CTD
PMID:31939706
NCBI chr13:35,768,652...36,131,939
Ensembl chr13:35,768,652...36,131,382
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DCLK3
doublecortin like kinase 3
increases expression
ISO
tributyltin results in increased expression of DCLK3 mRNA
CTD
PMID:31939706
NCBI chr 3:36,712,421...36,764,553
Ensembl chr 3:36,712,421...36,764,553
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DDIT3
DNA damage inducible transcript 3
increases expression
EXP
tributyltin results in increased expression of DDIT3 mRNA
CTD
PMID:23743301
NCBI chr12:57,516,588...57,520,517
Ensembl chr12:57,516,588...57,521,737
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DDIT4
DNA damage inducible transcript 4
increases expression
EXP
tributyltin results in increased expression of DDIT4 mRNA
CTD
PMID:24356939
NCBI chr10:72,273,924...72,276,036
Ensembl chr10:72,273,919...72,276,036
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DEGS2
delta 4-desaturase, sphingolipid 2
increases expression
ISO
tributyltin results in increased expression of DEGS2 mRNA
CTD
PMID:31939706
NCBI chr14:100,143,957...100,166,886
Ensembl chr14:100,143,957...100,159,645
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DENND10
DENN domain containing 10
increases expression
ISO
tributyltin results in increased expression of DENND10 mRNA
CTD
PMID:31129395
NCBI chr10:119,104,113...119,137,984
Ensembl chr10:119,104,086...119,137,984
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DFFB
DNA fragmentation factor subunit beta
multiple interactions increases response to substance
EXP
DFFB protein promotes the reaction [tributyltin results in decreased expression of CASP3 protein]; DFFB protein promotes the reaction [tributyltin results in decreased expression of CASP6 protein]; DFFB protein promotes the reaction [tributyltin results in increased cleavage of PARP1 protein]; DFFB protein promotes the reaction [tributyltin results in increased expression of H2AX protein modified form] DFFB protein results in increased susceptibility to tributyltin
CTD
PMID:31401084
NCBI chr 1:3,857,476...3,885,429
Ensembl chr 1:3,857,267...3,885,429
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DGAT1
diacylglycerol O-acyltransferase 1
increases expression multiple interactions
ISO EXP
tributyltin results in increased expression of DGAT1 mRNA [tributyltin co-treated with LHB protein] results in increased expression of DGAT1 mRNA
CTD
PMID:23428407 PMID:38630605
NCBI chr 8:144,314,584...144,326,852
Ensembl chr 8:144,314,584...144,326,910
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DGAT2
diacylglycerol O-acyltransferase 2
increases expression
ISO
tributyltin results in increased expression of DGAT2 mRNA
CTD
PMID:23428407
NCBI chr11:75,768,778...75,801,534
Ensembl chr11:75,759,512...75,801,535
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DHRS9
dehydrogenase/reductase 9
decreases expression
ISO
tributyltin results in decreased expression of DHRS9 mRNA
CTD
PMID:31939706
NCBI chr 2:169,067,077...169,096,167
Ensembl chr 2:169,064,789...169,096,167
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DHX35
DEAH-box helicase 35
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of DHX35 mRNA
CTD
PMID:31129395
NCBI chr20:38,962,344...39,039,721
Ensembl chr20:38,962,299...39,039,723
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DHX40
DEAH-box helicase 40
increases expression multiple interactions
ISO
tributyltin results in increased expression of DHX40 mRNA [bisphenol A co-treated with tributyltin] results in increased expression of DHX40 mRNA
CTD
PMID:31129395
NCBI chr17:59,565,610...59,608,345
Ensembl chr17:59,565,558...59,608,345
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DKK1
dickkopf WNT signaling pathway inhibitor 1
decreases expression
EXP
tributyltin results in decreased expression of DKK1 mRNA
CTD
PMID:28011154
NCBI chr10:52,314,281...52,317,657
Ensembl chr10:52,314,281...52,318,042
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DKK3
dickkopf WNT signaling pathway inhibitor 3
increases expression
ISO
tributyltin results in increased expression of DKK3 mRNA
CTD
PMID:21683754
NCBI chr11:11,963,036...12,009,745
Ensembl chr11:11,956,207...12,009,769
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DLK1
delta like non-canonical Notch ligand 1
decreases expression
ISO
tributyltin results in decreased expression of DLK1 mRNA
CTD
PMID:23322813 PMID:24513447
NCBI chr14:100,726,892...100,738,224
Ensembl chr14:100,725,705...100,738,224
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DMAP1
DNA methyltransferase 1 associated protein 1
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of DMAP1 mRNA
CTD
PMID:31129395
NCBI chr 1:44,213,471...44,220,673
Ensembl chr 1:44,213,455...44,220,681
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DMBT1
deleted in malignant brain tumors 1
increases expression
ISO
tributyltin results in increased expression of DMBT1 mRNA
CTD
PMID:31939706
NCBI chr10:122,560,754...122,643,736
Ensembl chr10:122,560,665...122,643,736
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DMP1
dentin matrix acidic phosphoprotein 1
decreases expression multiple interactions
ISO EXP
tributyltin results in decreased expression of DMP1 mRNA tributyltin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of DMP1 mRNA]
CTD
PMID:25777084 PMID:25932594
NCBI chr 4:87,650,280...87,664,357
Ensembl chr 4:87,650,280...87,664,361
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DNAI4
dynein axonemal intermediate chain 4
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of DNAI4 mRNA
CTD
PMID:31129395
NCBI chr 1:66,812,885...66,924,856
Ensembl chr 1:66,812,885...66,924,856
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DNAJC12
DnaJ heat shock protein family (Hsp40) member C12
decreases expression
ISO
tributyltin results in decreased expression of DNAJC12 mRNA
CTD
PMID:31939706
NCBI chr10:67,796,669...67,838,188
Ensembl chr10:67,796,669...67,838,188
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DNMT3B
DNA methyltransferase 3 beta
decreases expression
ISO
tributyltin results in decreased expression of DNMT3B mRNA
CTD
PMID:31939706
NCBI chr20:32,762,385...32,809,356
Ensembl chr20:32,762,385...32,809,359
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DOK4
docking protein 4
increases expression
ISO
tributyltin results in increased expression of DOK4 mRNA
CTD
PMID:31939706
NCBI chr16:57,471,922...57,487,322
Ensembl chr16:57,471,922...57,487,327
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DPEP1
dipeptidase 1
increases expression
ISO
tributyltin results in increased expression of DPEP1 mRNA
CTD
PMID:31939706
NCBI chr16:89,613,308...89,641,540
Ensembl chr16:89,613,308...89,638,456
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DPEP2
dipeptidase 2
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of DPEP2 mRNA
CTD
PMID:31129395
NCBI chr16:67,987,390...68,000,619
Ensembl chr16:67,987,394...68,000,586
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DPT
dermatopontin
increases expression
ISO
tributyltin results in increased expression of DPT mRNA
CTD
PMID:21683754
NCBI chr 1:168,695,468...168,729,206
Ensembl chr 1:168,695,468...168,729,206
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DSPP
dentin sialophosphoprotein
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of DSPP mRNA
CTD
PMID:31129395
NCBI chr 4:87,608,529...87,616,873
Ensembl chr 4:87,608,529...87,616,873
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DUSP10
dual specificity phosphatase 10
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of DUSP10 mRNA
CTD
PMID:31129395
NCBI chr 1:221,701,424...221,742,089
Ensembl chr 1:221,701,424...221,742,089
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DUSP13B
dual specificity phosphatase 13B
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of DUSP13B mRNA
CTD
PMID:31129395
NCBI chr10:75,094,434...75,109,191
Ensembl chr10:75,094,432...75,109,206 Ensembl chr10:75,094,432...75,109,206
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DYRK1B
dual specificity tyrosine phosphorylation regulated kinase 1B
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of DYRK1B mRNA
CTD
PMID:31129395
NCBI chr19:39,825,350...39,834,162
Ensembl chr19:39,825,350...39,834,201
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DYSF
dysferlin
decreases expression
ISO
tributyltin results in decreased expression of DYSF mRNA
CTD
PMID:21683754
NCBI chr 2:71,453,561...71,686,763
Ensembl chr 2:71,453,561...71,686,763
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ECHDC1
ethylmalonyl-CoA decarboxylase 1
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of ECHDC1 mRNA
CTD
PMID:31129395
NCBI chr 6:127,288,712...127,343,609
Ensembl chr 6:127,288,712...127,343,609
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EDN1
endothelin 1
increases expression
ISO
tributyltin results in increased expression of EDN1 mRNA
CTD
PMID:31129395
NCBI chr 6:12,230,516...12,297,194
Ensembl chr 6:12,290,361...12,297,194
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EEF2K
eukaryotic elongation factor 2 kinase
increases expression
ISO
tributyltin results in increased expression of EEF2K mRNA
CTD
PMID:21683754
NCBI chr16:22,206,278...22,288,738
Ensembl chr16:22,206,278...22,288,738
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EFEMP1
EGF containing fibulin extracellular matrix protein 1
increases expression
ISO
tributyltin results in increased expression of EFEMP1 mRNA
CTD
PMID:21683754
NCBI chr 2:55,865,967...55,923,782
Ensembl chr 2:55,865,967...55,924,139
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EGR1
early growth response 1
decreases expression
ISO
tributyltin results in decreased expression of EGR1 mRNA
CTD
PMID:31939706
NCBI chr 5:138,465,479...138,469,303
Ensembl chr 5:138,465,479...138,469,303
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EGR2
early growth response 2
increases expression
EXP
tributyltin results in increased expression of EGR2 mRNA
CTD
PMID:28011154
NCBI chr10:62,811,996...62,819,167
Ensembl chr10:62,811,996...62,819,167
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EGR4
early growth response 4
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of EGR4 mRNA
CTD
PMID:31129395
NCBI chr 2:73,290,929...73,293,548
Ensembl chr 2:73,290,929...73,293,701
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EHD2
EH domain containing 2
increases expression
ISO
tributyltin results in increased expression of EHD2 mRNA
CTD
PMID:21683754
NCBI chr19:47,713,422...47,743,134
Ensembl chr19:47,713,422...47,743,134
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EIF2S1
eukaryotic translation initiation factor 2 subunit alpha
increases phosphorylation multiple interactions
EXP
tributyltin results in increased phosphorylation of EIF2S1 protein Dantrolene inhibits the reaction [tributyltin results in increased phosphorylation of EIF2S1 protein]
CTD
PMID:23743301
NCBI chr14:67,360,328...67,386,516
Ensembl chr14:67,360,328...67,386,516
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EIF4B
eukaryotic translation initiation factor 4B
multiple interactions
EXP
tributyltin affects the expression of and results in increased phosphorylation of EIF4B protein
CTD
PMID:36372856
NCBI chr12:53,006,456...53,042,215
Ensembl chr12:53,006,282...53,042,215
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EIF4E
eukaryotic translation initiation factor 4E
multiple interactions
EXP
tributyltin affects the expression of and results in increased phosphorylation of EIF4E protein
CTD
PMID:36372856
NCBI chr 4:98,879,276...98,929,133
Ensembl chr 4:98,879,276...98,929,133
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ELAPOR1
endosome-lysosome associated apoptosis and autophagy regulator 1
increases expression
ISO
tributyltin results in increased expression of ELAPOR1 mRNA
CTD
PMID:31939706
NCBI chr 1:109,114,115...109,206,781
Ensembl chr 1:109,113,679...109,206,781
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ELF3
E74 like ETS transcription factor 3
increases expression
ISO
tributyltin results in increased expression of ELF3 mRNA
CTD
PMID:31939706
NCBI chr 1:202,010,587...202,017,183
Ensembl chr 1:202,007,945...202,017,183
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ELK4
ETS transcription factor ELK4
increases expression
ISO
tributyltin results in increased expression of ELK4 mRNA
CTD
PMID:31129395
NCBI chr 1:205,607,943...205,632,011
Ensembl chr 1:205,597,556...205,632,011
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ELMOD3
ELMO domain containing 3
increases expression
ISO
tributyltin results in increased expression of ELMOD3 mRNA
CTD
PMID:24848799
NCBI chr 2:85,354,769...85,391,748
Ensembl chr 2:85,354,394...85,391,752
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ELOVL3
ELOVL fatty acid elongase 3
decreases expression
ISO
tributyltin results in decreased expression of ELOVL3 mRNA
CTD
PMID:31939706
NCBI chr10:102,224,767...102,229,589
Ensembl chr10:102,226,299...102,229,589
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ELOVL7
ELOVL fatty acid elongase 7
increases expression
ISO
tributyltin results in increased expression of ELOVL7 mRNA
CTD
PMID:31939706
NCBI chr 5:60,751,791...60,844,269
Ensembl chr 5:60,751,791...60,844,274
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ENAM
enamelin
decreases expression multiple interactions
ISO
tributyltin results in decreased expression of ENAM mRNA Tetrachlorodibenzodioxin promotes the reaction [tributyltin results in decreased expression of ENAM mRNA]
CTD
PMID:22749964
NCBI chr 4:70,628,744...70,646,824
Ensembl chr 4:70,628,744...70,646,824
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ENDOG
endonuclease G
increases expression
ISO
tributyltin results in increased expression of ENDOG mRNA
CTD
PMID:24848799
NCBI chr 9:128,818,500...128,822,676
Ensembl chr 9:128,818,500...128,822,676
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EOMES
eomesodermin
decreases expression
ISO
tributyltin results in decreased expression of EOMES mRNA
CTD
PMID:33720505
NCBI chr 3:27,715,953...27,722,713
Ensembl chr 3:27,715,949...27,722,711
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EPB41L1
erythrocyte membrane protein band 4.1 like 1
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of EPB41L1 mRNA
CTD
PMID:31129395
NCBI chr20:36,091,414...36,232,799
Ensembl chr20:36,091,504...36,232,799
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EPCAM
epithelial cell adhesion molecule
increases expression
ISO
tributyltin results in increased expression of EPCAM mRNA
CTD
PMID:31939706
NCBI chr 2:47,369,311...47,387,020
Ensembl chr 2:47,345,158...47,387,601
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EPM2AIP1
EPM2A interacting protein 1
increases expression multiple interactions
ISO
tributyltin results in increased expression of EPM2AIP1 mRNA [bisphenol A co-treated with tributyltin] results in increased expression of EPM2AIP1 mRNA
CTD
PMID:31129395
NCBI chr 3:36,985,043...36,993,131
Ensembl chr 3:36,985,043...36,993,131
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ERBB2
erb-b2 receptor tyrosine kinase 2
increases expression
ISO
tributyltin results in increased expression of ERBB2 mRNA
CTD
PMID:31939706
NCBI chr17:39,688,094...39,728,658
Ensembl chr17:39,687,914...39,730,426
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ERG
ETS transcription factor ERG
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of ERG mRNA
CTD
PMID:31129395
NCBI chr21:38,367,261...38,661,783
Ensembl chr21:38,380,027...38,661,780
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ERMARD
ER membrane associated RNA degradation
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of ERMARD mRNA
CTD
PMID:31129395
NCBI chr 6:169,751,306...169,781,600
Ensembl chr 6:169,751,622...169,781,600
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ESR1
estrogen receptor 1
multiple interactions decreases expression affects expression increases expression
EXP ISO
tributyltin binds to and results in increased activity of ESR1 protein; tributyltin results in increased expression of and affects the localization of ESR1 protein tributyltin results in decreased expression of ESR1 protein tributyltin affects the expression of ESR1 protein fulvestrant inhibits the reaction [tributyltin affects the expression of ESR1 protein] Estrogens inhibits the reaction [tributyltin results in decreased expression of ESR1 protein]; fulvestrant inhibits the reaction [tributyltin results in decreased expression of ESR1 protein]; tributyltin inhibits the reaction [Estrogens results in increased expression of ESR1 protein] tributyltin results in increased expression of ESR1 mRNA
CTD
PMID:23523586 PMID:25819109 PMID:27521499 PMID:28161095 PMID:29908848 PMID:32239163 PMID:35295135 More...
NCBI chr 6:151,656,672...152,129,619
Ensembl chr 6:151,656,691...152,129,619
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ESR2
estrogen receptor 2
affects expression
ISO
tributyltin affects the expression of ESR2 protein
CTD
PMID:28161095
NCBI chr14:64,226,707...64,338,613
Ensembl chr14:64,084,232...64,338,112
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ETFBKMT
electron transfer flavoprotein subunit beta lysine methyltransferase
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of ETFBKMT mRNA
CTD
PMID:31129395
NCBI chr12:31,647,160...31,673,114
Ensembl chr12:31,647,160...31,673,114
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ETFDH
electron transfer flavoprotein dehydrogenase
increases expression multiple interactions
ISO
tributyltin results in increased expression of ETFDH mRNA [bisphenol A co-treated with tributyltin] results in increased expression of ETFDH mRNA
CTD
PMID:24848799 PMID:31129395
NCBI chr 4:158,672,296...158,709,623
Ensembl chr 4:158,671,968...158,710,742
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EVA1C
eva-1 homolog C
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of EVA1C mRNA
CTD
PMID:31129395
NCBI chr21:32,411,723...32,515,387
Ensembl chr21:32,412,006...32,515,397
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EXD2
exonuclease 3'-5' domain containing 2
multiple interactions increases expression
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of EXD2 mRNA tributyltin results in increased expression of EXD2 mRNA
CTD
PMID:31129395
NCBI chr14:69,191,498...69,244,018
Ensembl chr14:69,191,498...69,244,020
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EXO1
exonuclease 1
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of EXO1 mRNA
CTD
PMID:31129395
NCBI chr 1:241,847,986...241,889,939
Ensembl chr 1:241,847,967...241,895,148
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EXOC3L4
exocyst complex component 3 like 4
increases expression
ISO
tributyltin results in increased expression of EXOC3L4 mRNA
CTD
PMID:31939706
NCBI chr14:103,094,174...103,110,559
Ensembl chr14:103,094,725...103,110,559
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EXOSC3
exosome component 3
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of EXOSC3 mRNA
CTD
PMID:31129395
NCBI chr 9:37,779,714...37,785,092
Ensembl chr 9:37,759,234...37,832,117
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EZR
ezrin
increases expression
ISO
tributyltin results in increased expression of EZR mRNA
CTD
PMID:31939706
NCBI chr 6:158,765,748...158,819,368
Ensembl chr 6:158,765,741...158,819,368
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F11R
F11 receptor
decreases expression
EXP
tributyltin results in decreased expression of F11R mRNA
CTD
PMID:26314263
NCBI chr 1:160,995,211...161,021,152
Ensembl chr 1:160,995,211...161,021,175
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F13A1
coagulation factor XIII A chain
increases expression
ISO
tributyltin results in increased expression of F13A1 mRNA
CTD
PMID:21683754
NCBI chr 6:6,144,084...6,320,662
Ensembl chr 6:6,144,084...6,321,013
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F2RL1
F2R like trypsin receptor 1
increases expression
ISO
tributyltin results in increased expression of F2RL1 mRNA
CTD
PMID:31939706
NCBI chr 5:76,819,030...76,835,315
Ensembl chr 5:76,818,933...76,835,315
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FABP3
fatty acid binding protein 3
increases expression
ISO
tributyltin results in increased expression of FABP3 mRNA
CTD
PMID:23428407
NCBI chr 1:31,359,588...31,373,076
Ensembl chr 1:31,365,253...31,376,850
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FABP4
fatty acid binding protein 4
multiple interactions increases expression
ISO EXP
[triphenyltin chloride co-treated with tributyltin co-treated with dibutyldichlorotin] results in increased expression of FABP4 protein; diazepinylbenzoic acid inhibits the reaction [tributyltin results in increased expression of FABP4 mRNA]; dibutyldichlorotin inhibits the reaction [tributyltin results in increased expression of FABP4 protein]; T 0070907 inhibits the reaction [tributyltin results in increased expression of FABP4 mRNA]; tributyltin promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of FABP4 mRNA]; triphenyltin chloride affects the reaction [tributyltin results in increased expression of FABP4 protein] tributyltin results in increased expression of FABP4 mRNA; tributyltin results in increased expression of FABP4 protein
CTD
PMID:15993011 PMID:21622945 PMID:22197818 PMID:23322813 PMID:23428407 PMID:24155963 PMID:24513447 PMID:24848799 PMID:25777084 PMID:25932594 PMID:28011154 PMID:29787037 PMID:30027469 PMID:37142754 More...
NCBI chr 8:81,478,419...81,483,233
Ensembl chr 8:81,478,419...81,483,236
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FABP5
fatty acid binding protein 5
increases expression
ISO
tributyltin results in increased expression of FABP5 mRNA
CTD
PMID:23428407 PMID:31939706
NCBI chr 8:81,280,536...81,284,775
Ensembl chr 8:81,280,536...81,284,777
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FAM117A
family with sequence similarity 117 member A
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of FAM117A mRNA
CTD
PMID:31129395
NCBI chr17:49,710,332...49,789,110
Ensembl chr17:49,710,332...49,789,180
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FAM131B
family with sequence similarity 131 member B
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of FAM131B mRNA
CTD
PMID:31129395
NCBI chr 7:143,353,400...143,382,304
Ensembl chr 7:143,353,400...143,362,770
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FAM13A
family with sequence similarity 13 member A
increases expression
ISO
tributyltin results in increased expression of FAM13A mRNA
CTD
PMID:31939706
NCBI chr 4:88,725,960...89,057,185
Ensembl chr 4:88,725,955...89,111,398
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FAM200C
family with sequence similarity 200 member C
increases expression
EXP
tributyltin results in increased expression of FAM200C mRNA
CTD
PMID:24356939
NCBI chr 5:160,393,148...160,400,054
Ensembl chr 5:160,393,148...160,400,054
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FAM209B
family with sequence similarity 209 member B
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of FAM209 mRNA
CTD
PMID:31129395
NCBI chr20:56,533,246...56,536,520
Ensembl chr20:56,533,246...56,536,520
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FAM227A
family with sequence similarity 227 member A
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of FAM227A mRNA
CTD
PMID:31129395
NCBI chr22:38,578,118...38,656,392
Ensembl chr22:38,578,118...38,656,629
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FAM76B
family with sequence similarity 76 member B
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of FAM76B mRNA
CTD
PMID:31129395
NCBI chr11:95,768,953...95,789,782
Ensembl chr11:95,768,953...95,790,409
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FAM83B
family with sequence similarity 83 member B
increases expression
ISO
tributyltin results in increased expression of FAM83B mRNA
CTD
PMID:31939706
NCBI chr 6:54,846,203...54,945,099
Ensembl chr 6:54,846,771...54,945,099
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FAM98A
family with sequence similarity 98 member A
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of FAM98A mRNA
CTD
PMID:31129395
NCBI chr 2:33,583,660...33,599,299
Ensembl chr 2:33,532,744...33,599,347
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FAS
Fas cell surface death receptor
increases expression
ISO
tributyltin results in increased expression of FAS protein
CTD
PMID:30172001
NCBI chr10:88,964,050...89,017,059
Ensembl chr10:88,953,813...89,029,605
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FASN
fatty acid synthase
increases expression multiple interactions
ISO EXP
tributyltin results in increased expression of FASN mRNA [tributyltin co-treated with LHB protein] results in increased expression of FASN mRNA
CTD
PMID:23322813 PMID:28011154 PMID:38630605
NCBI chr17:82,078,338...82,098,236
Ensembl chr17:82,078,338...82,098,294
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FAT4
FAT atypical cadherin 4
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of FAT4 mRNA
CTD
PMID:31129395
NCBI chr 4:125,314,955...125,492,932
Ensembl chr 4:125,314,918...125,492,932
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FBXL4
F-box and leucine rich repeat protein 4
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of FBXL4 mRNA
CTD
PMID:31129395
NCBI chr 6:98,868,535...98,947,946
Ensembl chr 6:98,868,535...98,948,006
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FCGBP
Fc gamma binding protein
increases expression
ISO
tributyltin results in increased expression of FCGBP mRNA
CTD
PMID:31939706
NCBI chr19:39,863,323...39,934,634
Ensembl chr19:39,863,323...39,934,626
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FECH
ferrochelatase
decreases activity
EXP
tributyltin results in decreased activity of FECH protein
CTD
PMID:2347080
NCBI chr18:57,544,377...57,586,702
Ensembl chr18:57,544,377...57,586,732
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FERMT1
FERM domain containing kindlin 1
increases expression
ISO
tributyltin results in increased expression of FERMT1 mRNA
CTD
PMID:31939706
NCBI chr20:6,074,845...6,123,030
Ensembl chr20:6,074,845...6,123,214
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FGA
fibrinogen alpha chain
decreases expression
ISO
tributyltin results in decreased expression of FGA mRNA
CTD
PMID:31939706
NCBI chr 4:154,583,126...154,590,742
Ensembl chr 4:154,583,126...154,590,742
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FGB
fibrinogen beta chain
decreases expression
ISO
tributyltin results in decreased expression of FGB mRNA
CTD
PMID:31939706
NCBI chr 4:154,562,980...154,572,807
Ensembl chr 4:154,563,011...154,572,807
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FGG
fibrinogen gamma chain
decreases expression
ISO
tributyltin results in decreased expression of FGG mRNA
CTD
PMID:31939706
NCBI chr 4:154,604,136...154,612,656
Ensembl chr 4:154,604,134...154,612,967
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FGL2
fibrinogen like 2
increases expression
ISO
tributyltin results in increased expression of FGL2 mRNA
CTD
PMID:21683754
NCBI chr 7:77,193,369...77,199,819
Ensembl chr 7:77,193,369...77,199,848
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FHIP1A
FHF complex subunit HOOK interacting protein 1A
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of FHIP1A mRNA
CTD
PMID:31129395
NCBI chr 4:151,409,176...151,670,503
Ensembl chr 4:151,409,176...151,670,503
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FHOD1
formin homology 2 domain containing 1
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of FHOD1 mRNA
CTD
PMID:31129395
NCBI chr16:67,229,389...67,247,481
Ensembl chr16:67,229,387...67,247,481
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FLI1
Fli-1 proto-oncogene, ETS transcription factor
increases expression
ISO
tributyltin results in increased expression of FLI1 mRNA
CTD
PMID:21683754
NCBI chr11:128,685,351...128,813,267
Ensembl chr11:128,686,535...128,813,267
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FN1
fibronectin 1
multiple interactions
ISO
tributyltin promotes the reaction [Tetrachlorodibenzodioxin results in decreased expression of FN1 mRNA]
CTD
PMID:22749964
NCBI chr 2:215,360,865...215,436,068
Ensembl chr 2:215,360,440...215,436,073
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FOS
Fos proto-oncogene, AP-1 transcription factor subunit
increases expression
ISO
tributyltin results in increased expression of FOS mRNA
CTD
PMID:21683754
NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,283,190
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FOSL1
FOS like 1, AP-1 transcription factor subunit
decreases expression
ISO
tributyltin results in decreased expression of FOSL1 mRNA
CTD
PMID:33720505
NCBI chr11:65,892,049...65,900,545
Ensembl chr11:65,892,049...65,900,573
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FOXO1
forkhead box O1
decreases expression
EXP
tributyltin results in decreased expression of FOXO1 mRNA
CTD
PMID:28011154
NCBI chr13:40,555,667...40,666,641
Ensembl chr13:40,555,667...40,666,641
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FSHB
follicle stimulating hormone subunit beta
multiple interactions decreases expression
ISO
Fatty Acids, Omega-3 inhibits the reaction [tributyltin results in decreased expression of FSHB protein]; tributyltin inhibits the reaction [Estrogens deficiency results in increased secretion of FSHB protein] tributyltin results in decreased expression of FSHB mRNA; tributyltin results in decreased expression of FSHB protein
CTD
PMID:28161095 PMID:32783468 PMID:35430282
NCBI chr11:30,231,014...30,235,194
Ensembl chr11:30,231,014...30,235,261
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FSHR
follicle stimulating hormone receptor
multiple interactions increases expression
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of FSHR protein tributyltin results in increased expression of FSHR protein
CTD
PMID:31129395
NCBI chr 2:48,962,157...49,154,515
Ensembl chr 2:48,962,157...49,154,527
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G0S2
G0/G1 switch 2
increases expression
ISO
tributyltin results in increased expression of G0S2 mRNA
CTD
PMID:21683754
NCBI chr 1:209,675,412...209,676,390
Ensembl chr 1:209,675,412...209,676,390
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G6PC1
glucose-6-phosphatase catalytic subunit 1
multiple interactions increases expression
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of G6PC1 mRNA tributyltin results in increased expression of G6PC1 protein
CTD
PMID:31129395 PMID:31306684
NCBI chr17:42,900,799...42,914,438
Ensembl chr17:42,900,797...42,914,438
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GAD2
glutamate decarboxylase 2
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of GAD2 mRNA
CTD
PMID:31129395
NCBI chr10:26,216,372...26,304,558
Ensembl chr10:26,216,665...26,304,558
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GADD45B
growth arrest and DNA damage inducible beta
increases expression
ISO
tributyltin results in increased expression of GADD45B mRNA
CTD
PMID:21683754
NCBI chr19:2,476,127...2,478,257
Ensembl chr19:2,476,122...2,478,805
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GADD45G
growth arrest and DNA damage inducible gamma
decreases expression
ISO
tributyltin results in decreased expression of GADD45G mRNA
CTD
PMID:31939706
NCBI chr 9:89,605,012...89,606,555
Ensembl chr 9:89,605,012...89,606,555
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GAL
galanin and GMAP prepropeptide
decreases expression increases activity
ISO EXP
tributyltin results in decreased expression of GAL protein tributyltin results in increased activity of GAL protein
CTD
PMID:27310180 PMID:36319700
NCBI chr11:68,684,544...68,691,175
Ensembl chr11:68,683,779...68,691,175
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GAL3ST3
galactose-3-O-sulfotransferase 3
decreases expression multiple interactions
ISO
tributyltin results in decreased expression of GAL3ST3 mRNA [bisphenol A co-treated with tributyltin] results in decreased expression of GAL3ST3 mRNA
CTD
PMID:31129395
NCBI chr11:66,040,765...66,049,161
Ensembl chr11:66,040,765...66,049,161
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GALK2
galactokinase 2
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of GALK2 mRNA
CTD
PMID:31129395
NCBI chr15:49,155,774...49,367,740
Ensembl chr15:49,155,656...49,367,869
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GALNT12
polypeptide N-acetylgalactosaminyltransferase 12
increases expression
ISO
tributyltin results in increased expression of GALNT12 mRNA
CTD
PMID:31939706
NCBI chr 9:98,807,670...98,850,081
Ensembl chr 9:98,807,670...98,850,081
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GALNT6
polypeptide N-acetylgalactosaminyltransferase 6
increases expression
ISO
tributyltin results in increased expression of GALNT6 mRNA
CTD
PMID:31939706
NCBI chr12:51,351,252...51,391,673
Ensembl chr12:51,351,247...51,392,867
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GALR2
galanin receptor 2
increases expression
ISO
tributyltin results in increased expression of GALR2 mRNA
CTD
PMID:21683754
NCBI chr17:76,071,962...76,077,537
Ensembl chr17:76,074,781...76,077,537
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GAPDH
glyceraldehyde-3-phosphate dehydrogenase
multiple interactions decreases expression
EXP
tributyltin promotes the reaction [Tretinoin results in decreased expression of GAPDH protein] tributyltin results in decreased expression of GAPDH protein
CTD
PMID:30806631
NCBI chr12:6,534,517...6,538,371
Ensembl chr12:6,534,512...6,538,374
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GAR1
GAR1 ribonucleoprotein
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of GAR1 mRNA
CTD
PMID:31129395
NCBI chr 4:109,815,510...109,824,737
Ensembl chr 4:109,815,510...109,824,740
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GATA4
GATA binding protein 4
increases expression multiple interactions
ISO EXP
tributyltin results in increased expression of GATA4 protein [bisphenol A co-treated with tributyltin] results in increased expression of GATA4 protein
CTD
PMID:31129395 PMID:36319700
NCBI chr 8:11,676,935...11,760,002
Ensembl chr 8:11,676,959...11,760,002
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GATA5
GATA binding protein 5
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of GATA5 mRNA
CTD
PMID:31129395
NCBI chr20:62,463,497...62,475,995
Ensembl chr20:62,463,497...62,475,995
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GATC
glutamyl-tRNA amidotransferase subunit C
increases expression
ISO
tributyltin results in increased expression of GATC mRNA
CTD
PMID:31129395
NCBI chr12:120,446,444...120,463,749
Ensembl chr12:120,446,444...120,463,749
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GBP1
guanylate binding protein 1
increases expression
ISO
tributyltin results in increased expression of GBP2B mRNA
CTD
PMID:31939706
NCBI chr 1:89,052,319...89,065,208
Ensembl chr 1:89,051,882...89,065,360
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GBX2
gastrulation brain homeobox 2
decreases expression
ISO
tributyltin results in decreased expression of GBX2 mRNA
CTD
PMID:21683754
NCBI chr 2:236,161,340...236,168,386
Ensembl chr 2:236,165,236...236,168,386
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GCC2
GRIP and coiled-coil domain containing 2
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of GCC2 mRNA
CTD
PMID:31129395
NCBI chr 2:108,449,206...108,509,415
Ensembl chr 2:108,449,107...108,509,415
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GCG
glucagon
decreases expression decreases secretion
ISO
tributyltin results in decreased expression of GCG mRNA tributyltin results in decreased secretion of GCG protein
CTD
PMID:31306684
NCBI chr 2:162,142,882...162,152,247
Ensembl chr 2:162,142,882...162,152,404
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GCGR
glucagon receptor
decreases expression
ISO
tributyltin results in decreased expression of GCGR protein
CTD
PMID:31306684
NCBI chr17:81,804,150...81,814,008
Ensembl chr17:81,804,132...81,814,008
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GCLC
glutamate-cysteine ligase catalytic subunit
multiple interactions
ISO
PRKCD gene mutant form promotes the reaction [tributyltin results in increased expression of GCLC mRNA]
CTD
PMID:25895139
NCBI chr 6:53,497,341...53,545,101
Ensembl chr 6:53,497,341...53,616,970
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GCLM
glutamate-cysteine ligase modifier subunit
multiple interactions
ISO
PRKCD gene mutant form promotes the reaction [tributyltin results in increased expression of GCLM mRNA]
CTD
PMID:25895139
NCBI chr 1:93,885,199...93,909,430
Ensembl chr 1:93,885,199...93,909,456
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GDA
guanine deaminase
increases expression
ISO
tributyltin results in increased expression of GDA mRNA
CTD
PMID:21683754 PMID:31939706
NCBI chr 9:72,114,608...72,259,869
Ensembl chr 9:72,114,595...72,257,193
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GDPD1
glycerophosphodiester phosphodiesterase domain containing 1
increases expression
ISO
tributyltin results in increased expression of GDPD1 mRNA
CTD
PMID:31939706
NCBI chr17:59,220,511...59,275,970
Ensembl chr17:59,220,467...59,275,970
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GEM
GTP binding protein overexpressed in skeletal muscle
increases expression
ISO
tributyltin results in increased expression of GEM mRNA
CTD
PMID:21683754
NCBI chr 8:94,249,253...94,262,319
Ensembl chr 8:94,249,253...94,262,350
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GET3
guided entry of tail-anchored proteins factor 3, ATPase
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of GET3 mRNA
CTD
PMID:31129395
NCBI chr19:12,737,106...12,748,323
Ensembl chr19:12,737,139...12,748,323
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GFAP
glial fibrillary acidic protein
decreases expression increases expression multiple interactions
ISO
tributyltin results in decreased expression of GFAP protein tributyltin results in increased expression of GFAP protein Phycocyanin inhibits the reaction [tributyltin results in increased expression of GFAP protein]
CTD
PMID:23743147 PMID:26079211
NCBI chr17:44,903,159...44,915,500
Ensembl chr17:44,903,159...44,916,937
G
GGACT
gamma-glutamylamine cyclotransferase
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of GGACT mRNA
CTD
PMID:31129395
NCBI chr13:100,530,180...100,588,789
Ensembl chr13:100,530,164...100,589,528
G
GIN1
gypsy retrotransposon integrase 1
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of GIN1 mRNA
CTD
PMID:31129395
NCBI chr 5:103,086,000...103,120,138
Ensembl chr 5:103,086,000...103,120,138
G
GIPC2
GIPC PDZ domain containing family member 2
increases expression
ISO
tributyltin results in increased expression of GIPC2 mRNA
CTD
PMID:31939706
NCBI chr 1:78,044,970...78,138,444
Ensembl chr 1:77,979,542...78,138,444
G
GJA1
gap junction protein alpha 1
decreases expression
ISO
tributyltin results in decreased expression of GJA1 protein
CTD
PMID:28707438
NCBI chr 6:121,435,646...121,449,727
Ensembl chr 6:121,435,595...121,449,727
G
GK
glycerol kinase
increases expression
ISO
tributyltin results in increased expression of GK mRNA
CTD
PMID:23322813
NCBI chr X:30,653,423...30,731,462
Ensembl chr X:30,653,359...30,731,462
G
GLRA3
glycine receptor alpha 3
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of GLRA3 mRNA
CTD
PMID:31129395
NCBI chr 4:174,636,920...174,829,247
Ensembl chr 4:174,636,920...174,829,247
G
GNG11
G protein subunit gamma 11
increases expression
ISO
tributyltin results in increased expression of GNG11 mRNA
CTD
PMID:21683754
NCBI chr 7:93,921,735...93,928,610
Ensembl chr 7:93,921,735...93,928,610
G
GNRH1
gonadotropin releasing hormone 1
decreases expression multiple interactions
ISO
tributyltin results in decreased expression of GNRH1 mRNA tributyltin inhibits the reaction [Estrogens deficiency results in increased expression of GNRH1 mRNA]; tributyltin inhibits the reaction [GNRH1 protein results in increased secretion of LHB protein]
CTD
PMID:28161095
NCBI chr 8:25,419,258...25,425,040
Ensembl chr 8:25,419,258...25,424,654
G
GON7
GON7 subunit of KEOPS complex
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of GON7 mRNA
CTD
PMID:31129395
NCBI chr14:93,202,894...93,207,065
Ensembl chr14:93,202,894...93,207,065
G
GPAT3
glycerol-3-phosphate acyltransferase 3
increases expression
ISO
tributyltin results in increased expression of GPAT3 mRNA
CTD
PMID:23428407
NCBI chr 4:83,535,587...83,605,875
Ensembl chr 4:83,535,914...83,605,875
G
GPC6
glypican 6
increases expression
ISO
tributyltin results in increased expression of GPC6 mRNA
CTD
PMID:31129395
NCBI chr13:93,216,529...94,408,020
Ensembl chr13:93,226,807...94,408,020
G
GPNMB
glycoprotein nmb
decreases expression
ISO
tributyltin results in decreased expression of GPNMB mRNA
CTD
PMID:31939706
NCBI chr 7:23,246,775...23,275,108
Ensembl chr 7:23,235,967...23,275,108
G
GPR155
G protein-coupled receptor 155
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of GPR155 mRNA
CTD
PMID:31129395
NCBI chr 2:174,431,571...174,487,029
Ensembl chr 2:174,431,571...174,487,094
G
GPR158
G protein-coupled receptor 158
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of GPR158 mRNA
CTD
PMID:31129395
NCBI chr10:25,175,001...25,602,229
Ensembl chr10:25,174,802...25,602,229
G
GPR45
G protein-coupled receptor 45
decreases expression
ISO
tributyltin results in decreased expression of GPR45 mRNA
CTD
PMID:31129395
NCBI chr 2:105,241,743...105,243,467
Ensembl chr 2:105,241,743...105,243,467
G
GPT2
glutamic--pyruvic transaminase 2
decreases expression
ISO
tributyltin results in decreased expression of GPT2 mRNA
CTD
PMID:31129395
NCBI chr16:46,884,362...46,931,289
Ensembl chr16:46,884,362...46,931,289
G
GPX6
glutathione peroxidase 6
increases expression
ISO
tributyltin results in increased expression of GPX6 mRNA
CTD
PMID:31939706
NCBI chr 6:28,503,296...28,515,793
Ensembl chr 6:28,503,296...28,528,215
G
GRB14
growth factor receptor bound protein 14
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of GRB14 mRNA
CTD
PMID:31129395
NCBI chr 2:164,492,417...164,621,482
Ensembl chr 2:164,492,417...164,621,482
G
GREM2
gremlin 2, DAN family BMP antagonist
increases expression
ISO
tributyltin results in increased expression of GREM2 mRNA
CTD
PMID:31939706
NCBI chr 1:240,489,573...240,612,155
Ensembl chr 1:240,489,573...240,612,155
G
GRIA1
glutamate ionotropic receptor AMPA type subunit 1
decreases expression
ISO
tributyltin results in decreased expression of GRIA1 mRNA
CTD
PMID:19591855
NCBI chr 5:153,489,615...153,813,869
Ensembl chr 5:153,489,615...153,813,869
G
GRIA2
glutamate ionotropic receptor AMPA type subunit 2
decreases expression
ISO
tributyltin results in decreased expression of GRIA2 mRNA; tributyltin results in decreased expression of GRIA2 protein
CTD
PMID:19591855
NCBI chr 4:157,220,120...157,366,075
Ensembl chr 4:157,204,182...157,387,146
G
GRIA3
glutamate ionotropic receptor AMPA type subunit 3
increases expression
ISO
tributyltin results in increased expression of GRIA3 mRNA
CTD
PMID:19591855
NCBI chr X:123,184,278...123,490,915
Ensembl chr X:123,184,153...123,490,915
G
GRIA4
glutamate ionotropic receptor AMPA type subunit 4
increases expression
ISO
tributyltin results in increased expression of GRIA4 mRNA
CTD
PMID:19591855
NCBI chr11:105,609,616...105,982,090
Ensembl chr11:105,609,535...105,982,090
G
GRIN1
glutamate ionotropic receptor NMDA type subunit 1
decreases expression
ISO
tributyltin results in decreased expression of GRIN1 mRNA
CTD
PMID:19591855
NCBI chr 9:137,139,154...137,168,756
Ensembl chr 9:137,138,346...137,168,756
G
GRIN2A
glutamate ionotropic receptor NMDA type subunit 2A
decreases expression
ISO
tributyltin results in decreased expression of GRIN2A mRNA
CTD
PMID:19591855
NCBI chr16:9,753,404...10,182,908
Ensembl chr16:9,753,404...10,183,337
G
GRIN2B
glutamate ionotropic receptor NMDA type subunit 2B
increases expression
ISO
tributyltin results in increased expression of GRIN2B mRNA
CTD
PMID:19591855
NCBI chr12:13,537,337...13,982,134
Ensembl chr12:13,437,942...13,982,002
G
GRK5
G protein-coupled receptor kinase 5
decreases expression
ISO
tributyltin results in decreased expression of GRK5 mRNA
CTD
PMID:31939706
NCBI chr10:119,207,571...119,459,745
Ensembl chr10:119,207,571...119,459,745
G
GRXCR2
glutaredoxin and cysteine rich domain containing 2
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of GRXCR2 mRNA
CTD
PMID:31129395
NCBI chr 5:145,857,670...145,931,673
Ensembl chr 5:145,858,521...145,937,126
G
GSDME
gasdermin E
increases expression
ISO
tributyltin results in increased expression of GSDME mRNA
CTD
PMID:24848799
NCBI chr 7:24,698,355...24,795,539
Ensembl chr 7:24,698,355...24,757,940
G
GSR
glutathione-disulfide reductase
multiple interactions increases expression
ISO
Acetylcysteine inhibits the reaction [tributyltin results in increased expression of GSR protein]; Phycocyanin inhibits the reaction [tributyltin results in increased expression of GSR protein]
CTD
PMID:26079211
NCBI chr 8:30,678,066...30,727,846
Ensembl chr 8:30,678,066...30,727,846
G
GSTA5
glutathione S-transferase alpha 5
increases expression
ISO
tributyltin results in increased expression of GSTA1 mRNA
CTD
PMID:31939706
NCBI chr 6:52,831,692...52,846,245
Ensembl chr 6:52,831,655...52,840,843
G
GSTO1
glutathione S-transferase omega 1
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of GSTO1 mRNA
CTD
PMID:31129395
NCBI chr10:104,254,173...104,267,455
Ensembl chr10:104,235,356...104,267,459
G
GTPBP6
GTP binding protein 6 (putative)
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of GTPBP6 mRNA
CTD
PMID:31129395
NCBI chr X:304,759...318,796 NCBI chr Y:304,759...318,796
Ensembl chr X:303,346...318,798 Ensembl chr Y:303,346...318,798
G
GUCY2C
guanylate cyclase 2C
increases expression
ISO
tributyltin results in increased expression of GUCY2C mRNA
CTD
PMID:31939706
NCBI chr12:14,612,632...14,696,599
Ensembl chr12:14,612,632...14,696,599
G
GUCY2D
guanylate cyclase 2D, retinal
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of GUCY2D mRNA
CTD
PMID:31129395
NCBI chr17:8,002,615...8,020,342
Ensembl chr17:8,002,615...8,020,342
G
GZMA
granzyme A
increases expression
ISO
tributyltin results in increased expression of GZMA mRNA
CTD
PMID:31939706
NCBI chr 5:55,102,646...55,110,252
Ensembl chr 5:55,102,646...55,110,252
G
H2AC4
H2A clustered histone 4
increases expression
ISO
tributyltin results in increased expression of H2AC4 mRNA
CTD
PMID:31939706
NCBI chr 6:26,033,092...26,033,618
Ensembl chr 6:26,033,092...26,033,618
G
H2AX
H2A.X variant histone
increases expression multiple interactions increases phosphorylation
ISO EXP
tributyltin results in increased expression of H2AX protein modified form 2-(2,6-dimethylmorpholin-4-yl)-N-(5-(6-morpholin-4-yl-4-oxo-4H-pyran-2-yl)-9H-thioxanthen-2-yl)acetamide inhibits the reaction [tributyltin results in increased phosphorylation of H2AX protein]; DFFB protein promotes the reaction [tributyltin results in increased expression of H2AX protein modified form] Acetylcysteine inhibits the reaction [tributyltin results in increased expression of H2AX protein modified form]; Phycocyanin inhibits the reaction [tributyltin results in increased expression of H2AX protein modified form]
CTD
PMID:26079211 PMID:31401084 PMID:36319700
NCBI chr11:119,093,874...119,095,465
Ensembl chr11:119,093,874...119,095,465
G
H3C1
H3 clustered histone 1
increases expression
ISO
tributyltin results in increased expression of H3C1 mRNA
CTD
PMID:31939706
NCBI chr 6:26,020,451...26,020,958
Ensembl chr 6:26,020,451...26,020,958
G
H3C3
H3 clustered histone 3
increases expression
ISO
tributyltin results in increased expression of H3C3 mRNA
CTD
PMID:31939706
NCBI chr 6:26,045,384...26,045,869
Ensembl chr 6:26,045,384...26,045,869
G
HADH
hydroxyacyl-CoA dehydrogenase
increases expression
ISO
tributyltin results in increased expression of HADH mRNA
CTD
PMID:23428407
NCBI chr 4:107,989,889...108,035,171
Ensembl chr 4:107,989,714...108,035,241
G
HADHA
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha
increases expression
ISO
tributyltin results in increased expression of HADHA mRNA
CTD
PMID:23428407
NCBI chr 2:26,190,635...26,244,632
Ensembl chr 2:26,190,635...26,244,672
G
HADHB
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta
increases expression
ISO
tributyltin results in increased expression of HADHB mRNA
CTD
PMID:23428407 PMID:24848799
NCBI chr 2:26,244,939...26,290,465
Ensembl chr 2:26,243,170...26,290,465
G
HAMP
hepcidin antimicrobial peptide
decreases expression
ISO
tributyltin results in decreased expression of HAMP mRNA
CTD
PMID:31939706
NCBI chr19:35,282,528...35,285,143
Ensembl chr19:35,280,716...35,285,143
G
HAND1
heart and neural crest derivatives expressed 1
decreases expression
ISO
tributyltin results in decreased expression of HAND1 mRNA
CTD
PMID:33720505
NCBI chr 5:154,474,972...154,478,227
Ensembl chr 5:154,474,972...154,478,227
G
HAO2
hydroxyacid oxidase 2
increases expression
ISO
tributyltin results in increased expression of HAO2 mRNA
CTD
PMID:31129395
NCBI chr 1:119,368,785...119,394,130
Ensembl chr 1:119,368,779...119,394,130
G
HAT1
histone acetyltransferase 1
increases activity
ISO
tributyltin results in increased activity of HAT1 protein
CTD
PMID:15603928
NCBI chr 2:171,922,461...171,983,686
Ensembl chr 2:171,922,448...171,983,686
G
HDHD5
haloacid dehalogenase like hydrolase domain containing 5
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of HDHD5 mRNA
CTD
PMID:31129395
NCBI chr22:17,137,520...17,165,287
Ensembl chr22:17,137,511...17,165,287
G
HECTD2
HECT domain E3 ubiquitin protein ligase 2
increases expression
ISO
tributyltin results in increased expression of HECTD2 mRNA
CTD
PMID:31129395
NCBI chr10:91,409,235...91,514,820
Ensembl chr10:91,409,280...91,514,829
G
HEPH
hephaestin
increases expression
ISO
tributyltin results in increased expression of HEPH mRNA
CTD
PMID:31939706
NCBI chr X:66,162,671...66,268,863
Ensembl chr X:66,162,671...66,268,867
G
HJURP
Holliday junction recognition protein
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of HJURP mRNA
CTD
PMID:31129395
NCBI chr 2:233,836,702...233,854,535
Ensembl chr 2:233,833,416...233,854,566
G
HKDC1
hexokinase domain containing 1
increases expression
ISO
tributyltin results in increased expression of HKDC1 mRNA
CTD
PMID:31939706
NCBI chr10:69,220,332...69,267,552
Ensembl chr10:69,220,332...69,267,552
G
HLA-F
major histocompatibility complex, class I, F
increases expression
ISO
tributyltin results in increased expression of RT1-CE5 mRNA
CTD
PMID:21683754
NCBI chr 6:29,723,434...29,738,532
Ensembl chr 6:29,722,775...29,738,528
G
HMCES
5-hydroxymethylcytosine binding, ES cell specific
increases expression
ISO
tributyltin results in increased expression of HMCES mRNA
CTD
PMID:31129395
NCBI chr 3:129,278,832...129,306,186
Ensembl chr 3:129,278,828...129,306,186
G
HMGA1
high mobility group AT-hook 1
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of HMGA1 mRNA
CTD
PMID:31129395
NCBI chr 6:34,236,873...34,246,231
Ensembl chr 6:34,236,873...34,246,231
G
HMGCS2
3-hydroxy-3-methylglutaryl-CoA synthase 2
multiple interactions increases expression
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of HMGCS2 mRNA tributyltin results in increased expression of HMGCS2 mRNA
CTD
PMID:31129395
NCBI chr 1:119,747,996...119,768,932
Ensembl chr 1:119,748,002...119,768,905
G
HMMR
hyaluronan mediated motility receptor
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of HMMR mRNA
CTD
PMID:31129395
NCBI chr 5:163,460,632...163,491,941
Ensembl chr 5:163,460,203...163,491,941
G
HMOX1
heme oxygenase 1
increases expression
ISO
tributyltin results in increased expression of HMOX1 protein
CTD
PMID:28707438 PMID:36858641
NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214
G
HNRNPF
heterogeneous nuclear ribonucleoprotein F
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of HNRNPF mRNA
CTD
PMID:31129395
NCBI chr10:43,385,618...43,409,186
Ensembl chr10:43,385,617...43,409,186
G
HOXA2
homeobox A2
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of HOXA2 mRNA
CTD
PMID:31129395
NCBI chr 7:27,100,354...27,102,683
Ensembl chr 7:27,100,354...27,102,686
G
HPGD
15-hydroxyprostaglandin dehydrogenase
increases expression
ISO
tributyltin results in increased expression of HPGD mRNA
CTD
PMID:31939706
NCBI chr 4:174,490,175...174,522,893
Ensembl chr 4:174,490,175...174,523,154
G
HRH1
histamine receptor H1
decreases expression
EXP
tributyltin results in decreased expression of HRH1 mRNA
CTD
PMID:29580985
NCBI chr 3:11,137,238...11,263,557
Ensembl chr 3:11,137,093...11,263,557
G
HRH3
histamine receptor H3
decreases expression
ISO
tributyltin results in decreased expression of HRH3 mRNA
CTD
PMID:31129395
NCBI chr20:62,214,960...62,220,278
Ensembl chr20:62,214,960...62,220,278
G
HROB
homologous recombination factor with OB-fold
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of HROB mRNA
CTD
PMID:31129395
NCBI chr17:44,141,930...44,162,476
Ensembl chr17:44,141,906...44,162,476
G
HSD11B2
hydroxysteroid 11-beta dehydrogenase 2
decreases activity multiple interactions increases expression
EXP
tributyltin results in decreased activity of HSD11B2 protein Cycloheximide promotes the reaction [tributyltin results in increased expression of HSD11B2 mRNA]; Dactinomycin inhibits the reaction [tributyltin results in increased expression of HSD11B2 mRNA]; Glycyrrhetinic Acid inhibits the reaction [tributyltin results in increased activity of HSD11B2 protein]; LG 100754 inhibits the reaction [tributyltin results in increased activity of HSD11B2 protein]; RXRA protein affects the reaction [tributyltin results in increased expression of and results in increased activity of HSD11B2 protein]; RXRA protein affects the reaction [tributyltin results in increased expression of HSD11B2 mRNA]; RXRA protein affects the reaction [tributyltin results in increased expression of HSD11B2 protein]; tributyltin results in increased expression of and results in increased activity of HSD11B2 protein
CTD
PMID:16184081 PMID:22796344 PMID:31927052
NCBI chr16:67,429,801...67,437,553
Ensembl chr16:67,430,652...67,437,553
G
HSD17B1
hydroxysteroid 17-beta dehydrogenase 1
increases activity increases expression
EXP
tributyltin results in increased activity of HSD17B1 protein tributyltin results in increased expression of HSD17B1 mRNA
CTD
PMID:16513093
NCBI chr17:42,552,923...42,555,214
Ensembl chr17:42,552,922...42,555,214
G
HSD17B3
hydroxysteroid 17-beta dehydrogenase 3
decreases expression multiple interactions
ISO
tributyltin results in decreased expression of HSD17B3 mRNA; tributyltin results in decreased expression of HSD17B3 protein [bisphenol A co-treated with tributyltin] results in decreased expression of HSD17B3 mRNA
CTD
PMID:31129395 PMID:35430282
NCBI chr 9:96,235,306...96,302,176
Ensembl chr 9:96,235,306...96,302,176
G
HSD17B6
hydroxysteroid 17-beta dehydrogenase 6
increases expression
ISO
tributyltin results in increased expression of HSD17B6 mRNA
CTD
PMID:31939706
NCBI chr12:56,763,324...56,787,790
Ensembl chr12:56,752,161...56,787,790
G
HSD3B1
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
decreases expression
ISO
tributyltin results in decreased expression of HSD3B1 mRNA; tributyltin results in decreased expression of HSD3B1 protein
CTD
PMID:35430282
NCBI chr 1:119,507,203...119,515,058
Ensembl chr 1:119,507,198...119,515,054
G
HSD3B2
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
increases expression decreases expression
EXP
tributyltin results in increased expression of HSD3B2 mRNA tributyltin results in decreased expression of HSD3B2 mRNA
CTD
PMID:23523586 PMID:29549738
NCBI chr 1:119,414,931...119,423,034
Ensembl chr 1:119,414,931...119,423,035
G
HSPA1A
heat shock protein family A (Hsp70) member 1A
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of HSPA1A mRNA
CTD
PMID:31129395
NCBI chr 6:31,815,543...31,817,942
Ensembl chr 6:31,815,543...31,817,946
G
HSPA1B
heat shock protein family A (Hsp70) member 1B
decreases expression
ISO
tributyltin results in decreased expression of HSPA1B mRNA
CTD
PMID:31939706
NCBI chr 6:31,827,738...31,830,254
Ensembl chr 6:31,827,738...31,830,254
G
HSPA5
heat shock protein family A (Hsp70) member 5
multiple interactions decreases expression increases expression
EXP
4-phenylbutyric acid inhibits the reaction [tributyltin results in increased expression of HSPA5 protein]; 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [tributyltin results in increased expression of HSPA5 protein]; Dantrolene inhibits the reaction [tributyltin results in increased expression of HSPA5 protein] tributyltin results in decreased expression of HSPA5 mRNA
CTD
PMID:23743301 PMID:27678064
NCBI chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,382
G
HSPA8
heat shock protein family A (Hsp70) member 8
decreases expression
EXP
tributyltin results in decreased expression of HSPA8 mRNA
CTD
PMID:27678064
NCBI chr11:123,057,489...123,062,462
Ensembl chr11:123,057,489...123,063,230
G
HSPB8
heat shock protein family B (small) member 8
increases expression
ISO
tributyltin results in increased expression of HSPB8 mRNA
CTD
PMID:21683754
NCBI chr12:119,178,931...119,194,746
Ensembl chr12:119,171,555...119,224,855
G
HTR2A
5-hydroxytryptamine receptor 2A
decreases expression
EXP
tributyltin results in decreased expression of HTR2A mRNA
CTD
PMID:29580985
NCBI chr13:46,831,546...46,898,082
Ensembl chr13:46,831,546...46,897,076
G
ICAM1
intercellular adhesion molecule 1
increases expression
ISO EXP
tributyltin results in increased expression of ICAM1 mRNA
CTD
PMID:36319700
NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615
G
ID3
inhibitor of DNA binding 3
decreases expression
ISO
tributyltin results in decreased expression of ID3 mRNA
CTD
PMID:31939706
NCBI chr 1:23,557,926...23,559,501
Ensembl chr 1:23,557,926...23,559,501
G
IDH3A
isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha
increases expression multiple interactions
ISO EXP
tributyltin results in increased expression of IDH3A mRNA IDH3A protein affects the reaction [tributyltin results in decreased expression of CCNB1 protein]; IDH3A protein affects the reaction [tributyltin results in decreased expression of CDC25C protein]
CTD
PMID:23428407 PMID:26961604
NCBI chr15:78,149,362...78,171,945
Ensembl chr15:78,131,498...78,171,945
G
IER3
immediate early response 3
increases expression
ISO
tributyltin results in increased expression of IER3 mRNA
CTD
PMID:21683754
NCBI chr 6:30,743,199...30,744,547
Ensembl chr 6:30,743,199...30,744,548
G
IER3IP1
immediate early response 3 interacting protein 1
increases expression multiple interactions
ISO
tributyltin results in increased expression of IER3IP1 mRNA [bisphenol A co-treated with tributyltin] results in increased expression of IER3IP1 mRNA
CTD
PMID:31129395
NCBI chr18:47,152,834...47,176,364
Ensembl chr18:47,152,834...47,176,364
G
IFI27L2
interferon alpha inducible protein 27 like 2
increases expression
ISO
tributyltin results in increased expression of IFI27L2A mRNA
CTD
PMID:24848799
NCBI chr14:94,127,781...94,129,604
Ensembl chr14:94,127,779...94,130,253
G
IFITM3
interferon induced transmembrane protein 3
increases expression
ISO
tributyltin results in increased expression of IFITM3 mRNA
CTD
PMID:21683754
NCBI chr11:319,676...320,860
Ensembl chr11:319,676...329,475
G
IFNAR2
interferon alpha and beta receptor subunit 2
increases expression
ISO
tributyltin results in increased expression of IFNAR2 mRNA
CTD
PMID:30027469
NCBI chr21:33,229,938...33,265,664
Ensembl chr21:33,205,282...33,265,675
G
IFNG
interferon gamma
multiple interactions affects expression
EXP
4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [tributyltin results in increased expression of and results in increased secretion of IFNG protein]; tributyltin results in increased expression of and results in increased secretion of IFNG protein tributyltin affects the expression of IFNG mRNA
CTD
PMID:29532501
NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740
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IGDCC4
immunoglobulin superfamily DCC subclass member 4
increases expression
ISO
tributyltin results in increased expression of IGDCC4 mRNA
CTD
PMID:31939706
NCBI chr15:65,381,484...65,422,947
Ensembl chr15:65,381,484...65,422,947
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IGFBP1
insulin like growth factor binding protein 1
decreases expression
ISO
tributyltin results in decreased expression of IGFBP1 mRNA
CTD
PMID:31939706
NCBI chr 7:45,888,488...45,893,660
Ensembl chr 7:45,888,360...45,893,660
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IGSF11
immunoglobulin superfamily member 11
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of IGSF11 mRNA
CTD
PMID:31129395
NCBI chr 3:118,900,557...119,146,020
Ensembl chr 3:118,900,557...119,146,068
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IGSF23
immunoglobulin superfamily member 23
increases expression
ISO
tributyltin results in increased expression of IGSF23 mRNA
CTD
PMID:31939706
NCBI chr19:44,613,563...44,636,781
Ensembl chr19:44,613,563...44,636,781
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IGSF9
immunoglobulin superfamily member 9
increases expression
ISO
tributyltin results in increased expression of IGSF9 mRNA
CTD
PMID:31939706
NCBI chr 1:159,927,041...159,945,613
Ensembl chr 1:159,927,039...159,945,613
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IHH
Indian hedgehog signaling molecule
increases expression
ISO
tributyltin results in increased expression of IHH mRNA
CTD
PMID:31939706
NCBI chr 2:219,054,424...219,060,921
Ensembl chr 2:219,054,424...219,060,921
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IL10
interleukin 10
increases expression
ISO
tributyltin results in increased expression of IL10 mRNA
CTD
PMID:30027469
NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541
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IL13
interleukin 13
decreases expression
ISO
tributyltin results in decreased expression of IL13 protein
CTD
PMID:30172001
NCBI chr 5:132,656,522...132,661,110
Ensembl chr 5:132,656,263...132,661,110
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IL15
interleukin 15
multiple interactions
EXP
[tributyltin co-treated with LHB protein] results in decreased secretion of IL15 protein
CTD
PMID:38630605
NCBI chr 4:141,636,583...141,733,987
Ensembl chr 4:141,636,583...141,733,987
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IL16
interleukin 16
multiple interactions
EXP
[tributyltin co-treated with LHB protein] results in decreased secretion of IL16 protein
CTD
PMID:38630605
NCBI chr15:81,182,712...81,314,058
Ensembl chr15:81,159,575...81,314,058
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IL18
interleukin 18
multiple interactions
EXP
[tributyltin co-treated with LHB protein] results in increased secretion of IL18 protein
CTD
PMID:38630605
NCBI chr11:112,143,260...112,164,094
Ensembl chr11:112,143,251...112,164,096
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IL1A
interleukin 1 alpha
multiple interactions increases expression
ISO
1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid inhibits the reaction [tributyltin results in increased expression of IL1A protein]; Ethidium inhibits the reaction [tributyltin results in increased expression of IL1A protein]; Rotenone inhibits the reaction [tributyltin results in increased expression of IL1A protein]
CTD
PMID:8875956 PMID:9221826
NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493
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IL1B
interleukin 1 beta
affects secretion increases expression multiple interactions
EXP ISO
tributyltin affects the secretion of IL1B protein tributyltin results in increased expression of IL1B mRNA tributyltin results in increased expression of IL1B mRNA; tributyltin results in increased expression of IL1B protein 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [tributyltin results in increased expression of and results in increased secretion of IL1B protein]; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole affects the reaction [tributyltin affects the secretion of IL1B protein]; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [tributyltin results in increased expression of and results in increased secretion of IL1B protein]; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [tributyltin results in increased expression of IL1B mRNA]; CU-CPT22 inhibits the reaction [tributyltin results in increased expression of IL1B protein]; tributyltin results in increased expression of and results in increased secretion of IL1B protein; U 0126 affects the reaction [tributyltin affects the secretion of IL1B protein]
CTD
PMID:25382723 PMID:29951691 PMID:35405286 PMID:36319700
NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816
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IL1R1
interleukin 1 receptor type 1
decreases expression
ISO
tributyltin results in decreased expression of IL1R1 mRNA
CTD
PMID:31939706
NCBI chr 2:102,070,390...102,179,874
Ensembl chr 2:102,064,544...102,179,874
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IL3RA
interleukin 3 receptor subunit alpha
increases expression
ISO
tributyltin results in increased expression of IL3RA mRNA
CTD
PMID:31939706
NCBI chr X:1,336,785...1,382,689 NCBI chr Y:1,336,785...1,382,689
Ensembl chr Y:1,336,616...1,382,689 Ensembl chr X:1,336,616...1,382,689
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IL4
interleukin 4
decreases expression
ISO
tributyltin results in decreased expression of IL4 protein
CTD
PMID:30172001
NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678
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IL5RA
interleukin 5 receptor subunit alpha
decreases expression
ISO
tributyltin results in decreased expression of IL5RA mRNA
CTD
PMID:31129395
NCBI chr 3:3,066,324...3,110,374
Ensembl chr 3:3,066,324...3,126,613
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IL6
interleukin 6
increases expression multiple interactions
ISO EXP
tributyltin results in increased expression of IL6 protein tributyltin results in increased expression of IL6 mRNA; tributyltin results in increased expression of IL6 protein 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [tributyltin results in increased expression of IL6 mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [tributyltin results in increased expression of IL6 protein]; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [tributyltin results in increased expression of IL6 protein]; CU-CPT22 inhibits the reaction [tributyltin results in increased expression of IL6 protein]; tributyltin results in increased expression of and results in increased secretion of IL6 protein
CTD
PMID:23743147 PMID:29951691 PMID:30172001 PMID:35405286
NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002
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IL9
interleukin 9
multiple interactions
EXP
[tributyltin co-treated with LHB protein] results in increased secretion of IL9 protein
CTD
PMID:38630605
NCBI chr 5:135,892,246...135,895,841
Ensembl chr 5:135,892,246...135,895,841
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IMPG2
interphotoreceptor matrix proteoglycan 2
decreases expression
ISO
tributyltin results in decreased expression of IMPG2 mRNA
CTD
PMID:31129395
NCBI chr 3:101,222,546...101,320,575
Ensembl chr 3:101,222,546...101,320,575
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INHBB
inhibin subunit beta B
increases expression
ISO
tributyltin results in increased expression of INHBB mRNA
CTD
PMID:31129395
NCBI chr 2:120,346,136...120,351,803
Ensembl chr 2:120,346,136...120,351,803
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INS
insulin
multiple interactions increases expression
ISO EXP
tributyltin promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased abundance of Triglycerides]; tributyltin promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of ADIPOQ mRNA]; tributyltin promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of FABP4 mRNA]; tributyltin promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of LPL mRNA]; tributyltin promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of PPARG mRNA alternative form] tributyltin results in increased expression of INS2 mRNA [tributyltin co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 mRNA; [tributyltin co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 protein; Acetylcysteine inhibits the reaction [tributyltin promotes the reaction [Glucose results in increased secretion of INS protein]]; diazepinylbenzoic acid inhibits the reaction [[tributyltin co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 mRNA]; Fulvestrant inhibits the reaction [tributyltin promotes the reaction [Glucose results in increased secretion of INS protein]]; Ro 32-0432 inhibits the reaction [tributyltin promotes the reaction [Glucose results in increased secretion of INS protein]]; tributyltin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; tributyltin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of DMP1 mRNA]; tributyltin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA]; tributyltin promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of NR1H3 mRNA]; tributyltin promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SREBF1 mRNA]; tributyltin promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in decreased secretion of TNFRSF11B protein]; tributyltin promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of ADIPOQ protein]; tributyltin promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased secretion of ADIPOQ protein]; tributyltin promotes the reaction [Glucose results in increased secretion of INS protein]
CTD
PMID:22197818 PMID:25932594 PMID:28180948 PMID:31016361 PMID:31306684 PMID:34864131 More...
NCBI chr11:2,159,779...2,161,209
Ensembl chr11:2,159,779...2,161,221
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INS-IGF2
INS-IGF2 readthrough
multiple interactions increases expression increases secretion
ISO EXP
Acetylcysteine inhibits the reaction [tributyltin promotes the reaction [Glucose results in increased secretion of INS1 protein]]; Acetylcysteine inhibits the reaction [tributyltin results in increased secretion of INS1 protein]; Fulvestrant inhibits the reaction [tributyltin promotes the reaction [Glucose results in increased secretion of INS1 protein]]; Ro 32-0432 inhibits the reaction [tributyltin promotes the reaction [Glucose results in increased secretion of INS1 protein]]; tributyltin promotes the reaction [Glucose results in increased secretion of INS1 protein] tributyltin results in increased expression of INS1 mRNA; tributyltin results in increased expression of INS1 protein tributyltin promotes the reaction [[Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ADIPOQ protein] 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [tributyltin promotes the reaction [Glucose results in increased secretion of INS1 protein]]; Acetylcysteine inhibits the reaction [tributyltin promotes the reaction [Glucose results in increased secretion of INS1 protein]]; Fulvestrant inhibits the reaction [tributyltin promotes the reaction [Glucose results in increased secretion of INS1 protein]]; Ro 32-0432 inhibits the reaction [tributyltin promotes the reaction [Glucose results in increased secretion of INS1 protein]]; tributyltin promotes the reaction [Glucose results in increased secretion of INS1 protein]
CTD
PMID:27384973 PMID:28161095 PMID:28180948 PMID:28397090 PMID:30172001 PMID:32407875 More...
NCBI chr11:2,129,117...2,161,209
Ensembl chr11:2,132,538...2,161,209
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INSIG2
insulin induced gene 2
decreases expression
ISO
tributyltin results in decreased expression of INSIG2 mRNA
CTD
PMID:31939706
NCBI chr 2:118,088,471...118,110,997
Ensembl chr 2:118,088,452...118,110,997
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INSR
insulin receptor
affects methylation multiple interactions
EXP ISO
tributyltin affects the methylation of INSR gene tributyltin results in decreased expression of and results in decreased phosphorylation of INSR protein
CTD
PMID:28011154 PMID:28397090
NCBI chr19:7,112,265...7,294,414
Ensembl chr19:7,112,255...7,294,414
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IRF5
interferon regulatory factor 5
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of IRF5 mRNA
CTD
PMID:31129395
NCBI chr 7:128,937,032...128,950,038
Ensembl chr 7:128,937,457...128,950,038
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IRS1
insulin receptor substrate 1
multiple interactions increases expression
ISO
tributyltin results in decreased expression of and results in decreased phosphorylation of IRS1 protein tributyltin results in increased expression of IRS1 mRNA
CTD
PMID:28397090 PMID:30027469
NCBI chr 2:226,731,312...226,799,820
Ensembl chr 2:226,731,312...226,799,820
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ISOC1
isochorismatase domain containing 1
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of ISOC1 mRNA
CTD
PMID:31129395
NCBI chr 5:129,094,749...129,114,028
Ensembl chr 5:129,094,749...129,114,028
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ITGA4
integrin subunit alpha 4
increases expression
EXP
tributyltin results in increased expression of ITGA4 mRNA
CTD
PMID:26314263
NCBI chr 2:181,457,205...181,538,940
Ensembl chr 2:181,457,202...181,538,940
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ITGA6
integrin subunit alpha 6
increases expression
ISO
tributyltin results in increased expression of ITGA6 mRNA
CTD
PMID:31939706
NCBI chr 2:172,427,336...172,506,459
Ensembl chr 2:172,234,216...172,506,459
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ITGAL
integrin subunit alpha L
increases expression
EXP
tributyltin results in increased expression of ITGAL mRNA
CTD
PMID:26314263
NCBI chr16:30,472,742...30,523,185
Ensembl chr16:30,472,658...30,523,567
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ITGAM
integrin subunit alpha M
increases expression multiple interactions
ISO
tributyltin results in increased expression of ITGAM mRNA [Phycocyanin co-treated with tributyltin] results in increased expression of ITGAM protein Tetrachlorodibenzodioxin promotes the reaction [tributyltin results in increased expression of ITGAM mRNA]
CTD
PMID:22749964 PMID:26079211
NCBI chr16:31,259,975...31,332,877
Ensembl chr16:31,259,967...31,332,892
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ITGB2
integrin subunit beta 2
increases expression multiple interactions affects localization
EXP
tributyltin results in increased expression of ITGB2 mRNA 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [tributyltin affects the localization of ITGB2 protein]
CTD
PMID:20883105 PMID:26314263
NCBI chr21:44,885,953...44,928,815
Ensembl chr21:44,885,953...44,931,989
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ITGB4
integrin subunit beta 4
increases expression
ISO
tributyltin results in increased expression of ITGB4 mRNA
CTD
PMID:31939706
NCBI chr17:75,721,459...75,757,818
Ensembl chr17:75,721,328...75,757,818
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ITLN1
intelectin 1
increases expression
ISO
tributyltin results in increased expression of ITLN1 mRNA
CTD
PMID:31129395
NCBI chr 1:160,876,540...160,885,180
Ensembl chr 1:160,876,540...160,885,180
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ITPR3
inositol 1,4,5-trisphosphate receptor type 3
increases expression
ISO
tributyltin results in increased expression of ITPR3 mRNA
CTD
PMID:31939706
NCBI chr 6:33,621,322...33,696,562
Ensembl chr 6:33,620,365...33,696,574
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ITSN2
intersectin 2
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of ITSN2 mRNA
CTD
PMID:31129395
NCBI chr 2:24,202,864...24,361,368
Ensembl chr 2:24,202,864...24,360,536
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JAM2
junctional adhesion molecule 2
increases expression
ISO
tributyltin results in increased expression of JAM2 mRNA
CTD
PMID:24848799
NCBI chr21:25,639,258...25,717,562
Ensembl chr21:25,639,258...25,717,562
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JAM3
junctional adhesion molecule 3
increases expression
EXP
tributyltin results in increased expression of JAM3 mRNA
CTD
PMID:26314263
NCBI chr11:134,069,072...134,152,001
Ensembl chr11:134,069,071...134,152,001
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JCHAIN
joining chain of multimeric IgA and IgM
increases expression
ISO
tributyltin results in increased expression of JCHAIN mRNA
CTD
PMID:31939706
NCBI chr 4:70,655,541...70,666,508
Ensembl chr 4:70,655,541...70,681,817
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JHY
junctional cadherin complex regulator
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of JHY mRNA
CTD
PMID:31129395
NCBI chr11:122,882,759...122,963,862
Ensembl chr11:122,882,683...122,963,862
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JUN
Jun proto-oncogene, AP-1 transcription factor subunit
increases phosphorylation
EXP
tributyltin results in increased phosphorylation of JUN protein
CTD
PMID:21626652
NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,776,845...58,784,048
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JUNB
JunB proto-oncogene, AP-1 transcription factor subunit
increases expression
ISO
tributyltin results in increased expression of JUNB mRNA
CTD
PMID:21683754
NCBI chr19:12,791,486...12,793,315
Ensembl chr19:12,791,486...12,793,315
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KANK2
KN motif and ankyrin repeat domains 2
increases expression
ISO
tributyltin results in increased expression of KANK2 mRNA
CTD
PMID:31129395
NCBI chr19:11,164,270...11,197,865
Ensembl chr19:11,164,270...11,197,791
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KBTBD11
kelch repeat and BTB domain containing 11
increases expression
ISO
tributyltin results in increased expression of KBTBD11 mRNA
CTD
PMID:31939706
NCBI chr 8:1,973,677...2,006,936
Ensembl chr 8:1,973,677...2,006,936
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KCNK3
potassium two pore domain channel subfamily K member 3
increases expression
ISO
tributyltin results in increased expression of KCNK3 mRNA
CTD
PMID:24848799
NCBI chr 2:26,692,722...26,733,420
Ensembl chr 2:26,692,722...26,733,420
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KCNQ1
potassium voltage-gated channel subfamily Q member 1
increases expression
ISO
tributyltin results in increased expression of KCNQ1 mRNA
CTD
PMID:31939706
NCBI chr11:2,445,008...2,849,105
Ensembl chr11:2,444,654...2,849,105
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KCTD8
potassium channel tetramerization domain containing 8
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of KCTD8 mRNA
CTD
PMID:31129395
NCBI chr 4:44,173,903...44,448,809
Ensembl chr 4:44,173,903...44,448,809
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KEAP1
kelch like ECH associated protein 1
decreases expression
ISO
tributyltin results in decreased expression of KEAP1 protein
CTD
PMID:36858641
NCBI chr19:10,486,125...10,503,356
Ensembl chr19:10,486,125...10,503,558
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KIF2A
kinesin family member 2A
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of KIF2A mRNA
CTD
PMID:31129395
NCBI chr 5:62,306,206...62,391,025
Ensembl chr 5:62,306,162...62,391,025
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KIF3B
kinesin family member 3B
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of KIF3B mRNA
CTD
PMID:31129395
NCBI chr20:32,277,651...32,335,011
Ensembl chr20:32,277,651...32,335,011
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KISS1
KiSS-1 metastasis suppressor
multiple interactions
ISO
tributyltin inhibits the reaction [KISS1 protein results in increased secretion of LHB protein]
CTD
PMID:28161095
NCBI chr 1:204,190,341...204,196,491
Ensembl chr 1:204,190,341...204,196,491
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KLF15
KLF transcription factor 15
decreases expression
EXP
tributyltin results in decreased expression of KLF15 mRNA
CTD
PMID:28011154
NCBI chr 3:126,288,125...126,357,408
Ensembl chr 3:126,342,635...126,357,408
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KLF2
KLF transcription factor 2
increases expression
EXP
tributyltin results in increased expression of KLF2 mRNA
CTD
PMID:24356939
NCBI chr19:16,324,826...16,328,685
Ensembl chr19:16,324,826...16,328,685
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KLF4
KLF transcription factor 4
increases expression
ISO
tributyltin results in increased expression of KLF4 mRNA
CTD
PMID:31939706
NCBI chr 9:107,484,852...107,489,769
Ensembl chr 9:107,484,852...107,490,482
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KLHL9
kelch like family member 9
increases expression
ISO
tributyltin results in increased expression of KLHL9 mRNA
CTD
PMID:31129395
NCBI chr 9:21,329,665...21,335,404
Ensembl chr 9:21,320,024...21,335,404
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KNG1
kininogen 1
increases expression
ISO
tributyltin results in increased expression of KNG1 mRNA
CTD
PMID:30027469
NCBI chr 3:186,717,359...186,744,410
Ensembl chr 3:186,717,348...186,744,410
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KNSTRN
kinetochore localized astrin (SPAG5) binding protein
decreases expression
ISO
tributyltin results in decreased expression of KNSTRN mRNA
CTD
PMID:21683754
NCBI chr15:40,382,721...40,394,288
Ensembl chr15:40,382,721...40,394,288
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KRT19
keratin 19
increases expression
ISO
tributyltin results in increased expression of KRT19 mRNA
CTD
PMID:31939706
NCBI chr17:41,523,617...41,528,308
Ensembl chr17:41,523,617...41,528,308
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KRT79
keratin 79
increases expression
ISO
tributyltin results in increased expression of KRT79 mRNA
CTD
PMID:24848799
NCBI chr12:52,821,408...52,834,311
Ensembl chr12:52,821,408...52,834,311
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KSR1
kinase suppressor of ras 1
increases expression
ISO
tributyltin results in increased expression of KSR1 mRNA
CTD
PMID:31939706
NCBI chr17:27,456,448...27,626,435
Ensembl chr17:27,456,448...27,626,438
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LAMP3
lysosomal associated membrane protein 3
decreases expression
ISO
tributyltin results in decreased expression of LAMP3 mRNA
CTD
PMID:31129395
NCBI chr 3:183,122,215...183,163,813
Ensembl chr 3:183,122,215...183,163,839
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LARS2
leucyl-tRNA synthetase 2, mitochondrial
affects expression
ISO
tributyltin affects the expression of LARS2 mRNA
CTD
PMID:31939706
NCBI chr 3:45,388,576...45,549,407
Ensembl chr 3:45,388,561...45,554,726
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LEP
leptin
increases expression decreases expression multiple interactions increases secretion
EXP ISO
tributyltin results in increased expression of LEP mRNA tributyltin results in increased expression of LEP protein tributyltin results in decreased expression of LEP protein [Dietary Fats co-treated with tributyltin] results in increased expression of LEP protein tributyltin results in increased secretion of LEP protein
CTD
PMID:27310180 PMID:28011154 PMID:28161095 PMID:29787037 PMID:30172001
NCBI chr 7:128,241,278...128,257,629
Ensembl chr 7:128,241,278...128,257,629
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LEPR
leptin receptor
decreases expression
ISO
tributyltin results in decreased expression of LEPR mRNA
CTD
PMID:31939706
NCBI chr 1:65,420,652...65,641,559
Ensembl chr 1:65,420,652...65,641,559
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LETMD1
LETM1 domain containing 1
increases expression
ISO
tributyltin results in increased expression of LETMD1 mRNA
CTD
PMID:24848799
NCBI chr12:51,048,220...51,068,958
Ensembl chr12:51,047,962...51,060,424
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LGALS4
galectin 4
increases expression
ISO
tributyltin results in increased expression of LGALS4 mRNA
CTD
PMID:31939706
NCBI chr19:38,801,674...38,812,945
Ensembl chr19:38,801,671...38,812,945
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LHB
luteinizing hormone subunit beta
decreases secretion multiple interactions decreases expression increases secretion
ISO EXP
tributyltin results in decreased secretion of LHB protein [tributyltin co-treated with LHB protein] results in decreased secretion of CCL5 protein; [tributyltin co-treated with LHB protein] results in decreased secretion of CCL8 protein; [tributyltin co-treated with LHB protein] results in decreased secretion of CXCL13 protein; [tributyltin co-treated with LHB protein] results in decreased secretion of IL15 protein; [tributyltin co-treated with LHB protein] results in decreased secretion of IL16 protein; [tributyltin co-treated with LHB protein] results in decreased secretion of PDGFAA protein; [tributyltin co-treated with LHB protein] results in increased expression of ASCL1 mRNA; [tributyltin co-treated with LHB protein] results in increased expression of DGAT1 mRNA; [tributyltin co-treated with LHB protein] results in increased expression of FASN mRNA; [tributyltin co-treated with LHB protein] results in increased expression of PLIN1 mRNA; [tributyltin co-treated with LHB protein] results in increased expression of PNPLA2 mRNA; [tributyltin co-treated with LHB protein] results in increased expression of SREBF1 mRNA; [tributyltin co-treated with LHB protein] results in increased secretion of IL18 protein; [tributyltin co-treated with LHB protein] results in increased secretion of IL9 protein tributyltin results in decreased expression of LHB mRNA; tributyltin results in decreased expression of LHB protein tributyltin results in increased secretion of LHB protein [bisphenol A co-treated with tributyltin] results in increased secretion of LHB protein; Fatty Acids, Omega-3 inhibits the reaction [tributyltin results in decreased expression of LHB protein]; tributyltin inhibits the reaction [Estrogens deficiency results in increased secretion of LHB protein]; tributyltin inhibits the reaction [GNRH1 protein results in increased secretion of LHB protein]; tributyltin inhibits the reaction [KISS1 protein results in increased secretion of LHB protein]
CTD
PMID:28161095 PMID:31129395 PMID:32783468 PMID:35430282 PMID:38630605
NCBI chr19:49,015,980...49,019,498
Ensembl chr19:49,015,980...49,017,091
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LHCGR
luteinizing hormone/choriogonadotropin receptor
increases expression
ISO
tributyltin results in increased expression of LHCGR mRNA; tributyltin results in increased expression of LHCGR protein
CTD
PMID:35430282
NCBI chr 2:48,686,774...48,755,724
Ensembl chr 2:48,686,774...48,755,730
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LONP1
lon peptidase 1, mitochondrial
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of LONP1 mRNA
CTD
PMID:31129395
NCBI chr19:5,691,834...5,720,452
Ensembl chr19:5,691,834...5,720,572
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LOX
lysyl oxidase
increases expression
ISO
tributyltin results in increased expression of LOX mRNA
CTD
PMID:21683754
NCBI chr 5:122,063,195...122,078,259
Ensembl chr 5:122,063,195...122,078,413
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LOXL2
lysyl oxidase like 2
increases expression
ISO
tributyltin results in increased expression of LOXL2 mRNA
CTD
PMID:21683754
NCBI chr 8:23,296,897...23,404,120
Ensembl chr 8:23,296,897...23,425,328
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LOXL4
lysyl oxidase like 4
decreases expression
ISO
tributyltin results in decreased expression of LOXL4 mRNA
CTD
PMID:31939706
NCBI chr10:98,247,690...98,268,194
Ensembl chr10:98,247,690...98,268,194
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LPCAT3
lysophosphatidylcholine acyltransferase 3
increases expression
ISO
tributyltin results in increased expression of LPCAT3 mRNA
CTD
PMID:24848799
NCBI chr12:6,976,185...7,018,476
Ensembl chr12:6,976,185...7,018,477
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LPIN1
lipin 1
increases expression
ISO
tributyltin results in increased expression of LPIN1 mRNA
CTD
PMID:29908848
NCBI chr 2:11,677,544...11,827,409
Ensembl chr 2:11,677,595...11,827,409
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LPL
lipoprotein lipase
multiple interactions increases expression
ISO EXP
T 0070907 inhibits the reaction [tributyltin results in increased expression of LPL mRNA]; tributyltin promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of LPL mRNA]
CTD
PMID:22197818 PMID:23322813 PMID:24513447 PMID:28011154 PMID:29787037
NCBI chr 8:19,939,253...19,967,259
Ensembl chr 8:19,901,717...19,967,259
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LRCH2
leucine rich repeats and calponin homology domain containing 2
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of LRCH2 mRNA
CTD
PMID:31129395
NCBI chr X:115,110,616...115,234,096
Ensembl chr X:115,110,616...115,234,096
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LRFN3
leucine rich repeat and fibronectin type III domain containing 3
decreases expression
ISO
tributyltin results in decreased expression of LRFN3 mRNA
CTD
PMID:31939706
NCBI chr19:35,936,374...35,946,624
Ensembl chr19:35,935,358...35,946,624
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LRP11
LDL receptor related protein 11
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of LRP11 mRNA
CTD
PMID:31129395
NCBI chr 6:149,818,757...149,864,359
Ensembl chr 6:149,818,757...149,864,359
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LRP2
LDL receptor related protein 2
decreases expression
ISO
tributyltin results in decreased expression of LRP2 mRNA
CTD
PMID:31939706
NCBI chr 2:169,127,109...169,362,534
Ensembl chr 2:169,127,109...169,362,534
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LRRC1
leucine rich repeat containing 1
increases expression
ISO
tributyltin results in increased expression of LRRC1 mRNA
CTD
PMID:31939706
NCBI chr 6:53,795,005...53,924,125
Ensembl chr 6:53,794,497...53,924,125
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LRRC69
leucine rich repeat containing 69
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of LRRC69 mRNA
CTD
PMID:31129395
NCBI chr 8:91,102,619...91,219,257
Ensembl chr 8:91,101,832...91,219,257
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LRRC8B
leucine rich repeat containing 8 VRAC subunit B
increases expression
ISO
tributyltin results in increased expression of LRRC8B mRNA
CTD
PMID:31939706
NCBI chr 1:89,524,829...89,597,861
Ensembl chr 1:89,524,829...89,597,861
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LRRD1
leucine rich repeats and death domain containing 1
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of LRRD1 mRNA
CTD
PMID:31129395
NCBI chr 7:92,141,643...92,179,142
Ensembl chr 7:92,141,643...92,179,531
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LRTM1
leucine rich repeats and transmembrane domains 1
increases expression
ISO
tributyltin results in increased expression of LRTM1 mRNA
CTD
PMID:31939706
NCBI chr 3:54,918,231...54,967,102
Ensembl chr 3:54,918,231...54,967,088
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LSM2
LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of LSM2 mRNA
CTD
PMID:31129395
NCBI chr 6:31,797,396...31,806,966
Ensembl chr 6:31,797,396...31,806,966
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LTF
lactotransferrin
increases expression
ISO
tributyltin results in increased expression of LTF mRNA
CTD
PMID:31939706
NCBI chr 3:46,435,645...46,485,234
Ensembl chr 3:46,435,645...46,485,234
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LY6D
lymphocyte antigen 6 family member D
decreases expression
ISO
tributyltin results in decreased expression of LY6D mRNA
CTD
PMID:31939706
NCBI chr 8:142,784,882...142,786,539
Ensembl chr 8:142,784,882...142,786,539
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MAFA
MAF bZIP transcription factor A
decreases expression
ISO EXP
tributyltin results in decreased expression of MAFA mRNA
CTD
PMID:35563431
NCBI chr 8:143,428,064...143,430,732
Ensembl chr 8:143,419,182...143,430,732
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MAGEB18
MAGE family member B18
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of MAGEB18 mRNA
CTD
PMID:31129395
NCBI chr X:26,138,343...26,140,736
Ensembl chr X:26,138,343...26,140,736
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MAP2K3
mitogen-activated protein kinase kinase 3
decreases expression
EXP
tributyltin results in decreased expression of MAP2K3 mRNA
CTD
PMID:27678064
NCBI chr17:21,284,711...21,315,240
Ensembl chr17:21,284,672...21,315,232
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MAP3K5
mitogen-activated protein kinase kinase kinase 5
multiple interactions
EXP
tributyltin results in increased expression of and results in increased phosphorylation of MAP3K5 protein
CTD
PMID:24038145
NCBI chr 6:136,557,046...136,793,091
Ensembl chr 6:136,557,046...136,793,097
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MAP3K6
mitogen-activated protein kinase kinase kinase 6
decreases expression
ISO
tributyltin results in decreased expression of MAP3K6 mRNA
CTD
PMID:31939706
NCBI chr 1:27,355,184...27,366,961
Ensembl chr 1:27,355,184...27,366,961
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MAP3K7
mitogen-activated protein kinase kinase kinase 7
increases expression multiple interactions
ISO
tributyltin results in increased expression of MAP3K7 mRNA [bisphenol A co-treated with tributyltin] results in increased expression of MAP3K7 mRNA
CTD
PMID:31129395
NCBI chr 6:90,513,579...90,587,072
Ensembl chr 6:90,513,573...90,587,086
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MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
decreases expression
EXP
tributyltin results in decreased expression of MAP4K4 mRNA
CTD
PMID:27678064
NCBI chr 2:101,697,707...101,894,690
Ensembl chr 2:101,696,850...101,894,690
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MAPK1
mitogen-activated protein kinase 1
multiple interactions increases phosphorylation increases expression increases activity decreases expression
EXP ISO
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [tributyltin results in increased phosphorylation of MAPK1 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [tributyltin results in increased activity of MAPK1 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [tributyltin results in increased phosphorylation of MAPK1 protein]; [U 0126 co-treated with 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one] inhibits the reaction [tributyltin results in increased activity of MAPK1 protein]; Estradiol promotes the reaction [tributyltin results in increased expression of and results in increased phosphorylation of MAPK1 protein]; tributyltin affects the phosphorylation of and affects the activity of MAPK1 protein; tributyltin results in increased expression of and results in increased phosphorylation of MAPK1 protein; U 0126 inhibits the reaction [tributyltin results in increased activity of MAPK1 protein] tributyltin results in increased expression of MAPK1 protein tributyltin results in decreased expression of MAPK1 mRNA
CTD
PMID:11042092 PMID:18989867 PMID:22223438 PMID:23523586 PMID:23743147 PMID:26873547 PMID:27678064 PMID:30172001 PMID:34329126 More...
NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680
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MAPK12
mitogen-activated protein kinase 12
decreases expression
EXP
tributyltin results in decreased expression of MAPK12 mRNA
CTD
PMID:26314263
NCBI chr22:50,252,901...50,261,683
Ensembl chr22:50,245,450...50,261,716
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MAPK14
mitogen-activated protein kinase 14
increases expression
EXP
tributyltin results in increased expression of MAPK14 mRNA
CTD
PMID:26314263
NCBI chr 6:36,027,808...36,124,214
Ensembl chr 6:36,027,752...36,122,511
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MAPK3
mitogen-activated protein kinase 3
multiple interactions increases expression increases phosphorylation increases activity
EXP ISO
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [tributyltin results in increased phosphorylation of MAPK3 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [tributyltin results in increased activity of MAPK3 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [tributyltin results in increased phosphorylation of MAPK3 protein]; [U 0126 co-treated with 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one] inhibits the reaction [tributyltin results in increased activity of MAPK3 protein]; Estradiol promotes the reaction [tributyltin results in increased expression of and results in increased phosphorylation of MAPK3 protein]; tributyltin affects the phosphorylation of and affects the activity of MAPK3 protein; tributyltin results in increased expression of and results in increased phosphorylation of MAPK3 protein; U 0126 inhibits the reaction [tributyltin results in increased activity of MAPK3 protein] tributyltin results in increased expression of MAPK3 protein
CTD
PMID:11042092 PMID:18989867 PMID:22223438 PMID:23523586 PMID:23743147 PMID:26873547 PMID:30172001 PMID:34329126 More...
NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506
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MAPK8
mitogen-activated protein kinase 8
increases phosphorylation
EXP
tributyltin results in increased phosphorylation of MAPK8 protein
CTD
PMID:21626652
NCBI chr10:48,306,677...48,439,360
Ensembl chr10:48,306,639...48,439,360
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MAPT
microtubule associated protein tau
increases cleavage multiple interactions increases degradation
ISO
tributyltin results in increased cleavage of MAPT protein CAST protein inhibits the reaction [tributyltin results in increased degradation of MAPT protein]
CTD
PMID:23743147 PMID:33481012
NCBI chr17:45,894,554...46,028,334
Ensembl chr17:45,894,527...46,028,334
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MASP1
MBL associated serine protease 1
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of MASP1 mRNA
CTD
PMID:31129395
NCBI chr 3:187,217,282...187,291,737
Ensembl chr 3:187,217,282...187,291,980
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MC2R
melanocortin 2 receptor
multiple interactions
EXP
[Tetrachlorodibenzodioxin co-treated with 3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with perfluorooctane sulfonic acid co-treated with hexabromocyclododecane co-treated with 2,2',4,4'-tetrabromodiphenyl ether co-treated with tributyltin co-treated with methylmercuric chloride] results in increased expression of MC2R mRNA
CTD
PMID:25765474
NCBI chr18:13,882,044...13,915,707
Ensembl chr18:13,882,044...13,915,707
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MCRIP2
MAPK regulated corepressor interacting protein 2
increases expression
ISO
tributyltin results in increased expression of MCRIP2 mRNA
CTD
PMID:24848799
NCBI chr16:641,828...648,474
Ensembl chr16:636,817...648,474
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MCUR1
mitochondrial calcium uniporter regulator 1
increases expression
ISO
tributyltin results in increased expression of MCUR1 mRNA
CTD
PMID:24848799
NCBI chr 6:13,786,557...13,814,557
Ensembl chr 6:13,786,557...13,814,568
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MDH2
malate dehydrogenase 2
increases expression
ISO
tributyltin results in increased expression of MDH2 mRNA
CTD
PMID:23428407
NCBI chr 7:76,048,106...76,067,508
Ensembl chr 7:76,048,051...76,067,508
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ME2
malic enzyme 2
increases expression
ISO
tributyltin results in increased expression of ME2 mRNA
CTD
PMID:31939706
NCBI chr18:50,879,118...50,954,257
Ensembl chr18:50,879,080...50,954,257
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ME3
malic enzyme 3
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of ME3 mRNA
CTD
PMID:31129395
NCBI chr11:86,434,930...86,672,616
Ensembl chr11:86,441,108...86,672,636
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MED12L
mediator complex subunit 12L
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of MED12L mRNA
CTD
PMID:31129395
NCBI chr 3:151,085,664...151,436,653
Ensembl chr 3:151,085,286...151,437,072
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MED13
mediator complex subunit 13
increases expression
ISO
tributyltin results in increased expression of MED13 mRNA
CTD
PMID:21683754
NCBI chr17:61,942,605...62,065,278
Ensembl chr17:61,942,605...62,065,278
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MED18
mediator complex subunit 18
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of MED18 mRNA
CTD
PMID:31129395
NCBI chr 1:28,329,040...28,335,965
Ensembl chr 1:28,329,002...28,335,965
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MED29
mediator complex subunit 29
decreases expression
ISO
tributyltin results in decreased expression of MED29 mRNA
CTD
PMID:31129395
NCBI chr19:39,391,378...39,400,641
Ensembl chr19:39,391,303...39,400,641
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MEOX1
mesenchyme homeobox 1
increases expression
ISO
tributyltin results in increased expression of MEOX1 mRNA
CTD
PMID:31129395
NCBI chr17:43,640,389...43,661,922
Ensembl chr17:43,640,389...43,661,922
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MEP1B
meprin A subunit beta
increases expression
ISO
tributyltin results in increased expression of MEP1B mRNA
CTD
PMID:31939706
NCBI chr18:32,190,039...32,220,404
Ensembl chr18:32,185,069...32,220,404
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MESP1
mesoderm posterior bHLH transcription factor 1
decreases expression
ISO
tributyltin results in decreased expression of MESP1 mRNA
CTD
PMID:31129395
NCBI chr15:89,732,446...89,751,249
Ensembl chr15:89,749,875...89,751,249
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METTL1
methyltransferase 1, tRNA methylguanosine
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of METTL1 mRNA
CTD
PMID:31129395
NCBI chr12:57,768,471...57,772,105
Ensembl chr12:57,768,471...57,772,119
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MGAT4A
alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A
increases expression
ISO
tributyltin results in increased expression of MGAT4A mRNA
CTD
PMID:31939706
NCBI chr 2:98,619,106...98,731,132
Ensembl chr 2:98,619,106...98,731,132
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MGLL
monoglyceride lipase
increases expression
ISO
tributyltin results in increased expression of MGLL mRNA
CTD
PMID:21683754
NCBI chr 3:127,689,066...127,823,185
Ensembl chr 3:127,689,062...128,052,190
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MGMT
O-6-methylguanine-DNA methyltransferase
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of MGMT mRNA
CTD
PMID:31129395
NCBI chr10:129,467,241...129,770,983
Ensembl chr10:129,467,190...129,770,983
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MIB1
MIB E3 ubiquitin protein ligase 1
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of MIB1 mRNA
CTD
PMID:31129395
NCBI chr18:21,704,916...21,870,953
Ensembl chr18:21,704,957...21,870,953
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MICAL1
microtubule associated monooxygenase, calponin and LIM domain containing 1
increases expression
ISO
tributyltin results in increased expression of MICAL1 mRNA
CTD
PMID:31939706
NCBI chr 6:109,444,062...109,465,968
Ensembl chr 6:109,444,062...109,465,968
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MICB
MHC class I polypeptide-related sequence B
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of MICB mRNA
CTD
PMID:31129395
NCBI chr 6:31,494,918...31,511,124
Ensembl chr 6:31,494,881...31,511,124
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MISP
mitotic spindle positioning
increases expression
ISO
tributyltin results in increased expression of MISP mRNA
CTD
PMID:31939706
NCBI chr19:748,438...764,318
Ensembl chr19:751,112...764,318
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MKI67
marker of proliferation Ki-67
decreases expression multiple interactions
ISO
tributyltin results in decreased expression of MKI67 protein Fatty Acids, Omega-3 inhibits the reaction [tributyltin results in decreased expression of MKI67 protein]
CTD
PMID:32783468
NCBI chr10:128,096,659...128,126,423
Ensembl chr10:128,096,659...128,126,423
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MME
membrane metalloendopeptidase
increases expression
ISO
tributyltin results in increased expression of MME mRNA
CTD
PMID:31939706
NCBI chr 3:155,024,202...155,183,729
Ensembl chr 3:155,024,124...155,183,704
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MMP12
matrix metallopeptidase 12
decreases expression
ISO
tributyltin results in decreased expression of MMP12 mRNA
CTD
PMID:31939706
NCBI chr11:102,862,736...102,874,982
Ensembl chr11:102,862,736...102,874,982
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MMP13
matrix metallopeptidase 13
increases expression
ISO EXP
tributyltin results in increased expression of MMP13 mRNA
CTD
PMID:36319700
NCBI chr11:102,942,995...102,955,732
Ensembl chr11:102,942,995...102,955,732
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MMP2
matrix metallopeptidase 2
increases expression
ISO
tributyltin results in increased expression of MMP2 protein
CTD
PMID:28707438
NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691
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MMP8
matrix metallopeptidase 8
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of MMP8 mRNA
CTD
PMID:31129395
NCBI chr11:102,711,796...102,724,954
Ensembl chr11:102,711,796...102,727,050
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MMP9
matrix metallopeptidase 9
multiple interactions
ISO
tributyltin promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of MMP9 mRNA]
CTD
PMID:22749964
NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561
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MOGAT2
monoacylglycerol O-acyltransferase 2
increases expression
ISO
tributyltin results in increased expression of MOGAT2 mRNA
CTD
PMID:31939706
NCBI chr11:75,717,838...75,732,953
Ensembl chr11:75,717,838...75,732,958
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MOXD1
monooxygenase DBH like 1
decreases expression
ISO
tributyltin results in decreased expression of MOXD1 mRNA
CTD
PMID:31939706
NCBI chr 6:132,296,055...132,401,475
Ensembl chr 6:132,296,055...132,401,475
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MPC2
mitochondrial pyruvate carrier 2
increases expression
ISO
tributyltin results in increased expression of MPC2 mRNA
CTD
PMID:24848799
NCBI chr 1:167,916,675...167,937,072
Ensembl chr 1:167,916,675...167,937,072
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MPO
myeloperoxidase
increases activity
ISO
tributyltin results in increased activity of MPO protein
CTD
PMID:28161095 PMID:29908848 PMID:30172001
NCBI chr17:58,269,855...58,280,935
Ensembl chr17:58,269,855...58,280,935
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MPPE1
metallophosphoesterase 1
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of MPPE1 mRNA
CTD
PMID:31129395
NCBI chr18:11,882,622...11,908,317
Ensembl chr18:11,882,622...11,908,366
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MPV17L
MPV17 mitochondrial inner membrane protein like
multiple interactions increases expression
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of MPV17L mRNA tributyltin results in increased expression of MPV17L mRNA
CTD
PMID:31129395
NCBI chr16:15,395,754...15,413,271
Ensembl chr16:15,395,754...15,413,271
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MRAP
melanocortin 2 receptor accessory protein
increases expression
ISO
tributyltin results in increased expression of MRAP mRNA
CTD
PMID:24848799
NCBI chr21:32,291,813...32,314,784
Ensembl chr21:32,291,813...32,314,784
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MRPL18
mitochondrial ribosomal protein L18
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of MRPL18 mRNA
CTD
PMID:31129395
NCBI chr 6:159,789,812...159,798,429
Ensembl chr 6:159,789,812...159,798,436
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MRPL33
mitochondrial ribosomal protein L33
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of MRPL33 mRNA
CTD
PMID:31129395
NCBI chr 2:27,771,719...27,779,733
Ensembl chr 2:27,771,717...27,988,087
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MRPS33
mitochondrial ribosomal protein S33
multiple interactions increases expression
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of MRPS33 mRNA tributyltin results in increased expression of MRPS33 mRNA
CTD
PMID:31129395
NCBI chr 7:141,002,610...141,014,952
Ensembl chr 7:141,002,610...141,015,228
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MS4A8
membrane spanning 4-domains A8
increases expression
ISO
tributyltin results in increased expression of MS4A8A mRNA
CTD
PMID:31939706
NCBI chr11:60,699,612...60,715,807
Ensembl chr11:60,699,585...60,715,807
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MST1
macrophage stimulating 1
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of MST1 mRNA
CTD
PMID:31129395
NCBI chr 3:49,683,947...49,689,474
Ensembl chr 3:49,683,947...49,689,501
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MSX1
msh homeobox 1
multiple interactions decreases expression
ISO
Tetrachlorodibenzodioxin promotes the reaction [tributyltin results in decreased expression of MSX1 mRNA]
CTD
PMID:22749964
NCBI chr 4:4,859,665...4,863,936
Ensembl chr 4:4,859,665...4,863,936
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MT-ATP6
mitochondrially encoded ATP synthase membrane subunit 6
increases response to substance
EXP
ATP6 gene mutant form results in increased susceptibility to tributyltin
CTD
PMID:27129022
NCBI chr MT:8,527...9,207
Ensembl chr MT:8,527...9,207
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MT-ATP8
mitochondrially encoded ATP synthase membrane subunit 8
decreases expression
ISO
tributyltin results in decreased expression of ATP8 mRNA
CTD
PMID:31939706
NCBI chr MT:8,366...8,572
Ensembl chr MT:8,366...8,572
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MT1X
metallothionein 1X
decreases expression
ISO
tributyltin results in decreased expression of MT1 mRNA
CTD
PMID:31939706
NCBI chr16:56,682,470...56,684,196
Ensembl chr16:56,682,470...56,684,196
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MT2A
metallothionein 2A
decreases expression
ISO
tributyltin results in decreased expression of MT2 mRNA
CTD
PMID:31939706
NCBI chr16:56,608,584...56,609,497
Ensembl chr16:56,608,584...56,609,497
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MTHFR
methylenetetrahydrofolate reductase
decreases expression
ISO
tributyltin results in decreased expression of MTHFR mRNA
CTD
PMID:31939706
NCBI chr 1:11,785,723...11,805,964
Ensembl chr 1:11,785,723...11,806,455
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MTNR1A
melatonin receptor 1A
decreases expression
ISO
tributyltin results in decreased expression of MTNR1A mRNA
CTD
PMID:31939706
NCBI chr 4:186,533,655...186,555,567
Ensembl chr 4:186,526,792...186,555,567
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MTOR
mechanistic target of rapamycin kinase
decreases phosphorylation decreases expression
ISO
tributyltin results in decreased phosphorylation of MTOR protein tributyltin results in decreased expression of MTOR
CTD
PMID:20371977 PMID:26961604
NCBI chr 1:11,106,535...11,262,551
Ensembl chr 1:11,106,535...11,262,556
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MTPN
myotrophin
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of MTPN mRNA
CTD
PMID:31129395
NCBI chr 7:135,926,760...135,977,359
Ensembl chr 7:135,926,760...135,977,359
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MTTP
microsomal triglyceride transfer protein
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of MTTP mRNA
CTD
PMID:31129395
NCBI chr 4:99,564,130...99,623,997
Ensembl chr 4:99,564,081...99,623,997
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MXD1
MAX dimerization protein 1
increases expression
ISO
tributyltin results in increased expression of MXD1 mRNA
CTD
PMID:31939706
NCBI chr 2:69,915,109...69,942,945
Ensembl chr 2:69,897,688...69,942,945
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MXD4
MAX dimerization protein 4
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of MXD4 mRNA
CTD
PMID:31129395
NCBI chr 4:2,247,432...2,262,109
Ensembl chr 4:2,247,432...2,262,109
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MYD88
MYD88 innate immune signal transduction adaptor
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of MYD88 mRNA
CTD
PMID:31129395
NCBI chr 3:38,138,661...38,143,022
Ensembl chr 3:38,138,552...38,143,024
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MYL5
myosin light chain 5
decreases expression
EXP
tributyltin results in decreased expression of MYL5 mRNA
CTD
PMID:26314263
NCBI chr 4:674,542...682,028
Ensembl chr 4:673,580...682,028
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MYO15B
myosin XVB
increases expression
ISO
tributyltin results in increased expression of MYO15B mRNA
CTD
PMID:31939706
NCBI chr17:75,587,800...75,626,849
Ensembl chr17:75,587,800...75,626,849
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MYO5C
myosin VC
increases expression
ISO
tributyltin results in increased expression of MYO5C mRNA
CTD
PMID:31939706
NCBI chr15:52,192,322...52,295,804
Ensembl chr15:52,192,322...52,295,804
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MYO7B
myosin VIIB
increases expression
ISO
tributyltin results in increased expression of MYO7B mRNA
CTD
PMID:31939706
NCBI chr 2:127,535,683...127,637,726
Ensembl chr 2:127,535,683...127,637,729
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NACA
nascent polypeptide associated complex subunit alpha
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of NACA mRNA
CTD
PMID:31129395
NCBI chr12:56,712,427...56,725,299
Ensembl chr12:56,712,305...56,731,628
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NAGLU
N-acetyl-alpha-glucosaminidase
increases activity
ISO
tributyltin results in increased activity of NAGLU protein
CTD
PMID:29908848
NCBI chr17:42,536,241...42,544,449
Ensembl chr17:42,536,241...42,544,449
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NAMPT
nicotinamide phosphoribosyltransferase
increases expression
EXP
tributyltin results in increased expression of NAMPT mRNA
CTD
PMID:19371601
NCBI chr 7:106,248,298...106,285,888
Ensembl chr 7:106,248,298...106,285,966
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NBEAL2
neurobeachin like 2
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of NBEAL2 mRNA
CTD
PMID:31129395
NCBI chr 3:46,979,666...47,009,701
Ensembl chr 3:46,979,666...47,009,704
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NCAM1
neural cell adhesion molecule 1
affects localization multiple interactions
EXP
tributyltin affects the localization of NCAM1 protein 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [tributyltin affects the localization of NCAM1 protein]
CTD
PMID:20883105
NCBI chr11:112,961,420...113,278,436
Ensembl chr11:112,961,275...113,278,436
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NCAPH2
non-SMC condensin II complex subunit H2
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of NCAPH2 mRNA
CTD
PMID:31129395
NCBI chr22:50,508,224...50,524,780
Ensembl chr22:50,508,224...50,524,780
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NCOR1
nuclear receptor corepressor 1
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of NCOR1 mRNA
CTD
PMID:31129395
NCBI chr17:16,029,157...16,215,534
Ensembl chr17:16,029,065...16,218,185
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NDE1
nudE neurodevelopment protein 1
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of NDE1 mRNA
CTD
PMID:31129395
NCBI chr16:15,643,382...15,726,353
Ensembl chr16:15,643,267...15,734,691
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NDRG1
N-myc downstream regulated 1
increases expression
ISO
tributyltin results in increased expression of NDRG1 mRNA
CTD
PMID:21683754
NCBI chr 8:133,237,175...133,297,252
Ensembl chr 8:133,237,175...133,302,022
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NDUFA4
NDUFA4 mitochondrial complex associated
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of NDUFA4 mRNA
CTD
PMID:31129395
NCBI chr 7:10,931,943...10,940,153
Ensembl chr 7:10,931,943...10,940,153
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NDUFA5
NADH:ubiquinone oxidoreductase subunit A5
increases expression
ISO
tributyltin results in increased expression of NDUFA5 mRNA
CTD
PMID:24848799
NCBI chr 7:123,536,997...123,601,651
Ensembl chr 7:123,536,997...123,557,904
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NDUFS1
NADH:ubiquinone oxidoreductase core subunit S1
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of NDUFS1 mRNA
CTD
PMID:31129395
NCBI chr 2:206,114,817...206,159,444
Ensembl chr 2:206,114,817...206,159,509
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NEDD4L
NEDD4 like E3 ubiquitin protein ligase
decreases expression
ISO
tributyltin results in decreased expression of NEDD4L mRNA
CTD
PMID:31939706
NCBI chr18:58,044,226...58,401,540
Ensembl chr18:58,044,226...58,401,540
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NEFH
neurofilament heavy chain
multiple interactions decreases expression
ISO
Acetylcysteine inhibits the reaction [tributyltin results in decreased expression of NEFH protein]
CTD
PMID:26079211
NCBI chr22:29,480,218...29,491,390
Ensembl chr22:29,480,218...29,491,390
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NEFM
neurofilament medium chain
multiple interactions increases degradation
ISO
CAST protein inhibits the reaction [tributyltin results in increased degradation of NEFM protein]
CTD
PMID:33481012
NCBI chr 8:24,913,761...24,919,093
Ensembl chr 8:24,913,758...24,919,098
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NEIL3
nei like DNA glycosylase 3
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of NEIL3 mRNA
CTD
PMID:31129395
NCBI chr 4:177,309,874...177,371,268
Ensembl chr 4:177,309,874...177,362,936
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NEU3
neuraminidase 3
decreases expression
ISO
tributyltin results in decreased expression of NEU3 mRNA
CTD
PMID:31939706
NCBI chr11:74,980,515...75,020,676
Ensembl chr11:74,988,279...75,018,893
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NEURL3
neuralized E3 ubiquitin protein ligase 3
increases expression
ISO
tributyltin results in increased expression of NEURL3 mRNA
CTD
PMID:31939706
NCBI chr 2:96,497,646...96,508,109
Ensembl chr 2:96,497,646...96,508,109
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NF1
neurofibromin 1
increases expression
EXP
tributyltin results in increased expression of NF1 mRNA
CTD
PMID:26314263
NCBI chr17:31,094,927...31,377,677
Ensembl chr17:31,094,927...31,382,116
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NFATC1
nuclear factor of activated T cells 1
multiple interactions
ISO
Ro 41-5253 inhibits the reaction [tributyltin inhibits the reaction [TNFSF11 protein results in increased expression of NFATC1 protein]]; tributyltin inhibits the reaction [TNFSF11 protein results in increased expression of NFATC1 protein]
CTD
PMID:17291456
NCBI chr18:79,395,930...79,529,323
Ensembl chr18:79,395,856...79,529,325
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NFE2L2
NFE2 like bZIP transcription factor 2
multiple interactions increases localization increases expression
ISO
Acetylcysteine inhibits the reaction [tributyltin results in increased expression of NFE2L2 protein]; Phycocyanin inhibits the reaction [tributyltin results in increased expression of NFE2L2 protein] tributyltin results in increased localization of NFE2L2 protein PRKCD gene mutant form promotes the reaction [tributyltin affects the localization of and results in increased activity of NFE2L2 protein]
CTD
PMID:24055800 PMID:25895139 PMID:26079211 PMID:28707438 PMID:36858641
NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756
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NFIL3
nuclear factor, interleukin 3 regulated
decreases expression
ISO
tributyltin results in decreased expression of NFIL3 mRNA
CTD
PMID:31939706
NCBI chr 9:91,409,045...91,483,497
Ensembl chr 9:91,408,748...91,424,626
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NFKB1
nuclear factor kappa B subunit 1
increases expression
ISO
tributyltin results in increased expression of NFKB1 protein
CTD
PMID:30172001
NCBI chr 4:102,501,359...102,617,302
Ensembl chr 4:102,501,330...102,617,302
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NFKBIA
NFKB inhibitor alpha
affects expression decreases expression
EXP ISO
tributyltin affects the expression of NFKBIA mRNA tributyltin results in decreased expression of NFKBIA protein
CTD
PMID:27678064 PMID:30172001
NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749
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NGEF
neuronal guanine nucleotide exchange factor
increases expression
ISO
tributyltin results in increased expression of NGEF mRNA
CTD
PMID:31939706
NCBI chr 2:232,878,701...233,013,256
Ensembl chr 2:232,878,701...233,013,256
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NIPAL2
NIPA like domain containing 2
increases expression
ISO
tributyltin results in increased expression of NIPAL2 mRNA
CTD
PMID:21683754
NCBI chr 8:98,189,826...98,294,235
Ensembl chr 8:98,189,826...98,294,393
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NME2
NME/NM23 nucleoside diphosphate kinase 2
decreases expression multiple interactions
EXP
tributyltin results in decreased expression of NME2 protein Tretinoin promotes the reaction [tributyltin results in decreased expression of NME2 protein]
CTD
PMID:30806631
NCBI chr17:51,165,536...51,171,744
Ensembl chr17:51,165,435...51,171,744
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NOCT
nocturnin
increases expression
ISO
tributyltin results in increased expression of NOCT mRNA
CTD
PMID:24848799
NCBI chr 4:139,015,781...139,045,939
Ensembl chr 4:139,015,781...139,045,939
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NOL4
nucleolar protein 4
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of NOL4 mRNA
CTD
PMID:31129395
NCBI chr18:33,851,100...34,224,913
Ensembl chr18:33,851,100...34,224,952
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NOS1
nitric oxide synthase 1
decreases activity multiple interactions
ISO
tributyltin results in decreased activity of NOS1 protein CALM1 protein inhibits the reaction [tributyltin results in decreased activity of NOS1 protein]; tributyltin inhibits the reaction [CALM1 protein binds to NOS1 protein]
CTD
PMID:15464999
NCBI chr12:117,208,142...117,361,626
Ensembl chr12:117,208,142...117,452,170
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NOS1AP
nitric oxide synthase 1 adaptor protein
decreases expression
ISO
tributyltin results in decreased expression of NOS1AP mRNA
CTD
PMID:31939706
NCBI chr 1:162,069,691...162,370,475
Ensembl chr 1:162,069,691...162,370,475
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NOS2
nitric oxide synthase 2
increases expression
ISO
tributyltin results in increased expression of NOS2 protein
CTD
PMID:34902535
NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529
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NOS3
nitric oxide synthase 3
decreases expression multiple interactions
ISO
tributyltin results in decreased expression of NOS3 protein tributyltin results in decreased expression of and results in increased phosphorylation of NOS3 protein
CTD
PMID:26873547 PMID:34902535
NCBI chr 7:150,991,017...151,014,588
Ensembl chr 7:150,991,017...151,014,588
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NPAS2
neuronal PAS domain protein 2
decreases expression
ISO
tributyltin results in decreased expression of NPAS2 mRNA
CTD
PMID:31939706
NCBI chr 2:100,818,723...100,996,829
Ensembl chr 2:100,820,139...100,996,829
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NPY
neuropeptide Y
decreases expression
ISO
tributyltin results in decreased expression of NPY protein
CTD
PMID:27310180
NCBI chr 7:24,284,190...24,291,862
Ensembl chr 7:24,284,188...24,291,862
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NR1D1
nuclear receptor subfamily 1 group D member 1
increases expression
ISO
tributyltin results in increased expression of NR1D1 mRNA
CTD
PMID:31939706
NCBI chr17:40,092,793...40,100,589
Ensembl chr17:40,092,793...40,100,589
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NR1D2
nuclear receptor subfamily 1 group D member 2
increases expression
ISO
tributyltin results in increased expression of NR1D2 mRNA
CTD
PMID:31939706
NCBI chr 3:23,945,286...23,980,617
Ensembl chr 3:23,945,286...23,980,637
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NR1H3
nuclear receptor subfamily 1 group H member 3
multiple interactions increases expression
EXP ISO
tributyltin promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of NR1H3 mRNA] tributyltin results in increased expression of NR1H3 mRNA
CTD
PMID:23428407 PMID:24848799 PMID:25932594 PMID:28011154
NCBI chr11:47,248,300...47,269,033
Ensembl chr11:47,248,300...47,269,033
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NR1I2
nuclear receptor subfamily 1 group I member 2
multiple interactions
ISO EXP
tributyltin binds to and results in decreased activity of NR1I2 protein tributyltin binds to and results in increased activity of NR1I2 protein
CTD
PMID:33049310
NCBI chr 3:119,782,101...119,818,487
Ensembl chr 3:119,780,484...119,818,487
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NR4A1
nuclear receptor subfamily 4 group A member 1
decreases expression
ISO
tributyltin results in decreased expression of NR4A1 mRNA
CTD
PMID:30027469
NCBI chr12:52,022,832...52,059,503
Ensembl chr12:52,022,832...52,059,507
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NR5A1
nuclear receptor subfamily 5 group A member 1
decreases expression
ISO
tributyltin results in decreased expression of NR5A1 mRNA; tributyltin results in decreased expression of NR5A1 protein
CTD
PMID:35430282
NCBI chr 9:124,481,236...124,507,399
Ensembl chr 9:124,481,236...124,507,420
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NRDC
nardilysin convertase
decreases expression
EXP
tributyltin results in decreased expression of NRDC mRNA
CTD
PMID:26314263
NCBI chr 1:51,789,210...51,878,727
Ensembl chr 1:51,789,191...51,878,805
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NREP
neuronal regeneration related protein
increases expression
ISO
tributyltin results in increased expression of NREP mRNA
CTD
PMID:31939706
NCBI chr 5:111,728,802...111,976,932
Ensembl chr 5:111,662,621...111,997,464
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NSMCE3
NSE3 homolog, SMC5-SMC6 complex component
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of NSMCE3 mRNA
CTD
PMID:31129395
NCBI chr15:29,264,989...29,269,822
Ensembl chr15:29,264,989...29,269,822
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ODAM
odontogenic, ameloblast associated
increases expression
ISO
tributyltin results in increased expression of ODAM mRNA
CTD
PMID:31129395
NCBI chr 4:70,195,725...70,204,576
Ensembl chr 4:70,195,725...70,204,576
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OGDH
oxoglutarate dehydrogenase
increases expression
ISO
tributyltin results in increased expression of OGDH mRNA
CTD
PMID:23428407
NCBI chr 7:44,606,627...44,709,066
Ensembl chr 7:44,606,572...44,709,066
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OGG1
8-oxoguanine DNA glycosylase
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of OGG1 mRNA
CTD
PMID:31129395
NCBI chr 3:9,749,952...9,783,108
Ensembl chr 3:9,749,944...9,788,219
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ONECUT1
one cut homeobox 1
increases expression
ISO
tributyltin results in increased expression of ONECUT1 mRNA
CTD
PMID:31939706
NCBI chr15:52,755,053...52,790,336
Ensembl chr15:52,755,053...52,791,078
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OR10A6
olfactory receptor family 10 subfamily A member 6 (gene/pseudogene)
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of OR10A48 mRNA
CTD
PMID:31129395
NCBI chr11:7,924,592...7,931,268
Ensembl chr11:7,924,592...7,931,268
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OR13C3
olfactory receptor family 13 subfamily C member 3
decreases expression multiple interactions
ISO
tributyltin results in decreased expression of OR13C3C mRNA [bisphenol A co-treated with tributyltin] results in decreased expression of OR13C3 mRNA
CTD
PMID:31129395
NCBI chr 9:104,535,749...104,536,856
Ensembl chr 9:104,535,749...104,536,856
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OR13F1
olfactory receptor family 13 subfamily F member 1
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of OR13F5 mRNA
CTD
PMID:31129395
NCBI chr 9:104,504,263...104,505,222
Ensembl chr 9:104,504,263...104,505,222
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OR2M7
olfactory receptor family 2 subfamily M member 7
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of OR2T26 mRNA
CTD
PMID:31129395
NCBI chr 1:248,323,630...248,324,568
Ensembl chr 1:248,323,630...248,324,568
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OR51A7
olfactory receptor family 51 subfamily A member 7
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of OR51A7 mRNA
CTD
PMID:31129395
NCBI chr11:4,903,783...4,909,462
Ensembl chr11:4,903,783...4,909,462
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OR52P1
olfactory receptor family 52 subfamily P member 1 (gene/pseudogene)
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of OR52P1 mRNA
CTD
PMID:31129395
NCBI chr11:5,726,502...5,727,464
Ensembl chr11:5,726,502...5,727,464
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OR5AU1
olfactory receptor family 5 subfamily AU member 1
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of OR5AU1 mRNA
CTD
PMID:31129395
NCBI chr14:21,154,865...21,156,063
Ensembl chr14:21,148,370...21,159,060
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OR5T3
olfactory receptor family 5 subfamily T member 3
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of OR5T5B mRNA
CTD
PMID:31129395
NCBI chr11:56,252,254...56,253,222
Ensembl chr11:56,252,254...56,253,222
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OR6F1
olfactory receptor family 6 subfamily F member 1
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of OR6F1 mRNA
CTD
PMID:31129395
NCBI chr 1:247,711,436...247,716,646
Ensembl chr 1:247,711,436...247,716,646
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OSBP
oxysterol binding protein
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of OSBP mRNA
CTD
PMID:31129395
NCBI chr11:59,574,398...59,615,774
Ensembl chr11:59,574,398...59,615,774
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OSBPL3
oxysterol binding protein like 3
multiple interactions increases expression
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of OSBPL3 mRNA tributyltin results in increased expression of OSBPL3 mRNA
CTD
PMID:31129395 PMID:31939706
NCBI chr 7:24,796,537...24,981,845
Ensembl chr 7:24,796,540...24,981,634
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OSGIN2
oxidative stress induced growth inhibitor family member 2
decreases expression multiple interactions
ISO
tributyltin results in decreased expression of OSGIN2 mRNA [bisphenol A co-treated with tributyltin] results in decreased expression of OSGIN2 mRNA
CTD
PMID:31129395
NCBI chr 8:89,901,868...89,927,888
Ensembl chr 8:89,901,849...89,927,888
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OTX2
orthodenticle homeobox 2
increases expression
ISO
tributyltin results in increased expression of OTX2 mRNA
CTD
PMID:21683754
NCBI chr14:56,799,905...56,810,479
Ensembl chr14:56,799,905...56,816,693
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OXCT1
3-oxoacid CoA-transferase 1
increases expression
ISO
tributyltin results in increased expression of OXCT1 mRNA
CTD
PMID:31939706
NCBI chr 5:41,730,065...41,870,425
Ensembl chr 5:41,730,065...41,870,425
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P2RY10
P2Y receptor family member 10
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of P2RY10 mRNA
CTD
PMID:31129395
NCBI chr X:78,945,391...78,963,727
Ensembl chr X:78,945,332...78,963,727
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P4HA3
prolyl 4-hydroxylase subunit alpha 3
increases expression
ISO
tributyltin results in increased expression of P4HA3 mRNA
CTD
PMID:21683754
NCBI chr11:74,250,146...74,311,640
Ensembl chr11:74,235,801...74,311,640
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PACC1
proton activated chloride channel 1
increases expression
ISO
tributyltin results in increased expression of PACC1 mRNA
CTD
PMID:24848799
NCBI chr 1:212,363,928...212,414,886
Ensembl chr 1:212,363,928...212,414,901
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PANK4
pantothenate kinase 4 (inactive)
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of PANK4 mRNA
CTD
PMID:31129395
NCBI chr 1:2,508,537...2,526,596
Ensembl chr 1:2,508,537...2,526,597
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PAQR4
progestin and adipoQ receptor family member 4
increases expression
ISO
tributyltin results in increased expression of PAQR4 mRNA
CTD
PMID:31939706
NCBI chr16:2,969,348...2,973,484
Ensembl chr16:2,969,270...2,973,484
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PARD6B
par-6 family cell polarity regulator beta
increases expression
EXP
tributyltin results in increased expression of PARD6B mRNA
CTD
PMID:26314263
NCBI chr20:50,731,580...50,753,741
Ensembl chr20:50,731,580...50,756,795
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PARM1
prostate androgen-regulated mucin-like protein 1
increases expression
ISO
tributyltin results in increased expression of PARM1 mRNA
CTD
PMID:24848799
NCBI chr 4:74,933,116...75,050,113
Ensembl chr 4:74,933,095...75,050,115
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PARP1
poly(ADP-ribose) polymerase 1
multiple interactions increases cleavage
ISO EXP
[bisphenol A co-treated with tributyltin] results in increased expression of PARP1 mRNA tributyltin results in increased cleavage of PARP1 protein DFFB protein promotes the reaction [tributyltin results in increased cleavage of PARP1 protein]
CTD
PMID:31129395 PMID:31401084
NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154
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PATE4
prostate and testis expressed 4
decreases expression
ISO
tributyltin results in decreased expression of PATE4 mRNA
CTD
PMID:31129395
NCBI chr11:125,833,316...125,840,072
Ensembl chr11:125,833,316...125,840,072
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PC
pyruvate carboxylase
increases expression
ISO
tributyltin results in increased expression of PCX mRNA
CTD
PMID:23428407
NCBI chr11:66,848,420...66,958,383
Ensembl chr11:66,848,417...66,958,386
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PCK1
phosphoenolpyruvate carboxykinase 1
increases expression
ISO
tributyltin results in increased expression of PCK1 mRNA
CTD
PMID:23428407 PMID:24848799
NCBI chr20:57,561,110...57,568,121
Ensembl chr20:57,561,080...57,568,121
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PCK2
phosphoenolpyruvate carboxykinase 2, mitochondrial
increases expression
ISO
tributyltin results in increased expression of PCK2 protein
CTD
PMID:31306684
NCBI chr14:24,094,171...24,104,125
Ensembl chr14:24,094,053...24,110,598
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PCMTD2
protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of PCMTD2 mRNA
CTD
PMID:31129395
NCBI chr20:64,255,748...64,276,226
Ensembl chr20:64,255,695...64,304,820
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PCSK1N
proprotein convertase subtilisin/kexin type 1 inhibitor
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of PCSK1N mRNA
CTD
PMID:31129395
NCBI chr X:48,831,096...48,835,610
Ensembl chr X:48,831,096...48,835,610
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PCSK4
proprotein convertase subtilisin/kexin type 4
increases expression
ISO
tributyltin results in increased expression of PCSK4 mRNA
CTD
PMID:31939706
NCBI chr19:1,481,428...1,490,876
Ensembl chr19:1,481,428...1,490,752
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PCYOX1
prenylcysteine oxidase 1
increases expression
ISO
tributyltin results in increased expression of PCYOX1 mRNA
CTD
PMID:24848799
NCBI chr 2:70,257,915...70,281,185
Ensembl chr 2:70,257,386...70,281,185
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PDCD7
programmed cell death 7
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of PDCD7 mRNA
CTD
PMID:31129395
NCBI chr15:65,117,379...65,133,808
Ensembl chr15:65,117,379...65,133,808
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PDE4D
phosphodiesterase 4D
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of PDE4D mRNA
CTD
PMID:31129395
NCBI chr 5:58,969,038...60,522,128
Ensembl chr 5:58,969,038...60,522,120
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PDHB
pyruvate dehydrogenase E1 subunit beta
increases expression
ISO
tributyltin results in increased expression of PDHB mRNA
CTD
PMID:23428407
NCBI chr 3:58,427,630...58,433,832
Ensembl chr 3:58,427,630...58,433,857
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PDK2
pyruvate dehydrogenase kinase 2
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of PDK2 mRNA
CTD
PMID:31129395
NCBI chr17:50,094,737...50,112,152
Ensembl chr17:50,094,737...50,112,152
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PDK4
pyruvate dehydrogenase kinase 4
decreases expression
ISO
tributyltin results in decreased expression of PDK4 mRNA
CTD
PMID:31939706
NCBI chr 7:95,583,499...95,596,516
Ensembl chr 7:95,583,499...95,596,516
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PDS5A
PDS5 cohesin associated factor A
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of PDS5A mRNA
CTD
PMID:31129395
NCBI chr 4:39,822,863...39,977,911
Ensembl chr 4:39,822,863...39,977,956
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PDS5B
PDS5 cohesin associated factor B
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of PDS5B mRNA
CTD
PMID:31129395
NCBI chr13:32,586,452...32,778,019
Ensembl chr13:32,586,452...32,778,019
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PDX1
pancreatic and duodenal homeobox 1
multiple interactions decreases expression
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of PDX1 mRNA tributyltin results in decreased expression of PDX1 mRNA
CTD
PMID:31129395 PMID:35563431
NCBI chr13:27,920,000...27,926,313
Ensembl chr13:27,920,000...27,926,313
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PER2
period circadian regulator 2
increases expression
ISO
tributyltin results in increased expression of PER2 mRNA
CTD
PMID:31939706
NCBI chr 2:238,244,044...238,300,065
Ensembl chr 2:238,244,044...238,290,102
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PER3
period circadian regulator 3
increases expression
ISO
tributyltin results in increased expression of PER3 mRNA
CTD
PMID:31939706
NCBI chr 1:7,784,291...7,845,177
Ensembl chr 1:7,784,291...7,845,177
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PFKFB4
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
increases expression
ISO
tributyltin results in increased expression of PFKFB4 mRNA
CTD
PMID:31939706
NCBI chr 3:48,517,684...48,563,136
Ensembl chr 3:48,517,684...48,562,015
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PGM3
phosphoglucomutase 3
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of PGM3 mRNA
CTD
PMID:31129395
NCBI chr 6:83,148,705...83,193,900
Ensembl chr 6:83,147,324...83,193,936
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PHEX
phosphate regulating endopeptidase X-linked
multiple interactions
ISO
tributyltin promotes the reaction [Tetrachlorodibenzodioxin results in decreased expression of PHEX mRNA]
CTD
PMID:22749964
NCBI chr X:22,032,325...22,251,310
Ensembl chr X:22,032,325...22,494,713
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PIGA
phosphatidylinositol glycan anchor biosynthesis class A
increases expression
ISO
tributyltin results in increased expression of PIGA mRNA
CTD
PMID:31129395
NCBI chr X:15,319,451...15,335,554
Ensembl chr X:15,319,452...15,335,554
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PIGO
phosphatidylinositol glycan anchor biosynthesis class O
decreases expression
ISO
tributyltin results in decreased expression of PIGO mRNA
CTD
PMID:31129395
NCBI chr 9:35,088,688...35,096,591
Ensembl chr 9:35,085,493...35,096,619
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PIK3CA
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
increases expression decreases expression
EXP
tributyltin results in increased expression of PIK3CA mRNA tributyltin results in decreased expression of PIK3CA mRNA
CTD
PMID:26314263 PMID:27678064
NCBI chr 3:179,148,126...179,240,093
Ensembl chr 3:179,148,114...179,240,093
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PIK3CB
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
increases expression
EXP
tributyltin results in increased expression of PIK3CB mRNA
CTD
PMID:26314263
NCBI chr 3:138,652,698...138,834,928
Ensembl chr 3:138,652,336...138,834,928
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PIK3CG
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
increases expression
EXP
tributyltin results in increased expression of PIK3CG mRNA
CTD
PMID:26314263
NCBI chr 7:106,865,282...106,908,980
Ensembl chr 7:106,865,278...106,908,980
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PITX3
paired like homeodomain 3
decreases expression
ISO
tributyltin results in decreased expression of PITX3 mRNA
CTD
PMID:31939706
NCBI chr10:102,230,189...102,241,512
Ensembl chr10:102,230,189...102,241,512
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PKM
pyruvate kinase M1/2
increases expression
ISO
tributyltin results in increased expression of PKM mRNA
CTD
PMID:31939706
NCBI chr15:72,199,029...72,231,591
Ensembl chr15:72,199,029...72,231,819
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PKP3
plakophilin 3
increases expression
ISO
tributyltin results in increased expression of PKP3 mRNA
CTD
PMID:31939706
NCBI chr11:392,596...404,908
Ensembl chr11:392,614...404,908
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PLAC8
placenta associated 8
increases expression
ISO
tributyltin results in increased expression of PLAC8 mRNA
CTD
PMID:31939706
NCBI chr 4:83,090,048...83,114,729
Ensembl chr 4:83,059,493...83,137,075
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PLCB4
phospholipase C beta 4
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of PLCB4 mRNA
CTD
PMID:31129395
NCBI chr20:9,068,678...9,480,808
Ensembl chr20:9,067,825...9,504,593
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PLCE1
phospholipase C epsilon 1
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of PLCE1 mRNA
CTD
PMID:31129395
NCBI chr10:93,993,931...94,332,823
Ensembl chr10:93,993,931...94,332,823
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PLCG1
phospholipase C gamma 1
decreases expression
EXP
tributyltin results in decreased expression of PLCG1 mRNA
CTD
PMID:26314263
NCBI chr20:41,137,543...41,177,626
Ensembl chr20:41,136,960...41,196,801
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PLCG2
phospholipase C gamma 2
decreases expression
EXP
tributyltin results in decreased expression of PLCG2 mRNA
CTD
PMID:26314263
NCBI chr16:81,739,041...81,962,685
Ensembl chr16:81,738,248...81,962,685
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PLD3
phospholipase D family member 3
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of PLD3 mRNA
CTD
PMID:31129395
NCBI chr19:40,348,695...40,378,485
Ensembl chr19:40,348,456...40,389,472
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PLEKHH1
pleckstrin homology, MyTH4 and FERM domain containing H1
increases expression
ISO
tributyltin results in increased expression of PLEKHH1 mRNA
CTD
PMID:31939706
NCBI chr14:67,533,290...67,589,612
Ensembl chr14:67,533,290...67,589,612
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PLIN1
perilipin 1
increases expression multiple interactions
ISO EXP
tributyltin results in increased expression of PLIN1 mRNA [tributyltin co-treated with LHB protein] results in increased expression of PLIN1 mRNA
CTD
PMID:23428407 PMID:25777084 PMID:25932594 PMID:30027469 PMID:38630605
NCBI chr15:89,664,367...89,679,367
Ensembl chr15:89,664,367...89,679,427
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PLIN2
perilipin 2
increases expression
ISO
tributyltin results in increased expression of PLIN2 mRNA
CTD
PMID:24848799
NCBI chr 9:19,108,388...19,127,492
Ensembl chr 9:19,108,375...19,149,290
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PLP2
proteolipid protein 2
increases expression
ISO
tributyltin results in increased expression of PLP2 mRNA
CTD
PMID:21683754
NCBI chr X:49,171,898...49,175,235
Ensembl chr X:49,171,898...49,175,235
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PLPP1
phospholipid phosphatase 1
decreases expression
EXP
tributyltin results in decreased expression of PPAP2A mRNA
CTD
PMID:26314263
NCBI chr 5:55,424,854...55,534,964
Ensembl chr 5:55,424,854...55,534,969
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PLS1
plastin 1
increases expression
ISO
tributyltin results in increased expression of PLS1 mRNA
CTD
PMID:31939706
NCBI chr 3:142,596,393...142,713,664
Ensembl chr 3:142,596,393...142,713,664
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PLXDC2
plexin domain containing 2
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of PLXDC2 mRNA
CTD
PMID:31129395
NCBI chr10:19,816,432...20,289,856
Ensembl chr10:19,816,239...20,289,856
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PNKD
PNKD metallo-beta-lactamase domain containing
decreases expression
ISO
tributyltin results in decreased expression of PNKD mRNA
CTD
PMID:31129395
NCBI chr 2:218,270,519...218,346,793
Ensembl chr 2:218,269,651...218,346,793
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PNLDC1
PARN like ribonuclease domain containing exonuclease 1
increases expression
ISO
tributyltin results in increased expression of PNLDC1 mRNA
CTD
PMID:31939706
NCBI chr 6:159,799,455...159,820,704
Ensembl chr 6:159,800,249...159,820,704
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PNMA8A
PNMA family member 8A
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of PNMA8A mRNA
CTD
PMID:31129395
NCBI chr19:46,466,503...46,471,563
Ensembl chr19:46,466,491...46,471,563
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PNPLA2
patatin like phospholipase domain containing 2
multiple interactions
EXP
[tributyltin co-treated with LHB protein] results in increased expression of PNPLA2 mRNA
CTD
PMID:38630605
NCBI chr11:818,914...825,573
Ensembl chr11:818,914...825,573
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PNPLA8
patatin like phospholipase domain containing 8
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of PNPLA8 mRNA
CTD
PMID:31129395
NCBI chr 7:108,470,417...108,528,178
Ensembl chr 7:108,470,417...108,569,666
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POC1B
POC1 centriolar protein B
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of POC1B mRNA
CTD
PMID:31129395
NCBI chr12:89,401,467...89,526,047
Ensembl chr12:89,419,718...89,526,047
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POR
cytochrome p450 oxidoreductase
increases expression
ISO
tributyltin results in increased expression of POR mRNA
CTD
PMID:24848799
NCBI chr 7:75,915,155...75,986,855
Ensembl chr 7:75,899,200...75,986,855
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POU5F2
POU domain class 5, transcription factor 2
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of POU5F2 mRNA
CTD
PMID:31129395
NCBI chr 5:93,733,220...93,741,600
Ensembl chr 5:93,733,220...93,741,600
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PPARA
peroxisome proliferator activated receptor alpha
increases expression
ISO
tributyltin results in increased expression of PPARA mRNA
CTD
PMID:23322813 PMID:30027469
NCBI chr22:46,150,526...46,243,756
Ensembl chr22:46,150,521...46,243,755
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PPARG
peroxisome proliferator activated receptor gamma
increases expression multiple interactions increases activity affects binding
ISO EXP
tributyltin results in increased expression of PPARG mRNA; tributyltin results in increased expression of PPARG protein [bisphenol A co-treated with tributyltin] results in increased expression of PPARG protein tributyltin results in increased activity of PPARG protein tributyltin binds to PPARG protein T 0070907 inhibits the reaction [tributyltin results in increased expression of PPARG mRNA]; tributyltin binds to and results in increased activity of PPARG protein; tributyltin inhibits the reaction [GW 1929 binds to PPARG protein]; tributyltin inhibits the reaction [Rosiglitazone binds to PPARG protein]; tributyltin inhibits the reaction [triphenyltin chloride binds to PPARG protein] [triphenyltin chloride co-treated with tributyltin co-treated with dibutyldichlorotin] results in increased expression of PPARG protein; PPARG protein promotes the reaction [tributyltin binds to and results in increased activity of PPARG protein]; T 0070907 inhibits the reaction [tributyltin binds to and results in increased activity of PPARG protein]; T 0070907 inhibits the reaction [tributyltin results in increased expression of PPARG mRNA]; tributyltin binds to and results in increased activity of PPARG protein; tributyltin promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of PPARG mRNA alternative form]
CTD
PMID:19497422 PMID:21622945 PMID:22197818 PMID:23322813 PMID:24155963 PMID:24513447 PMID:24786373 PMID:25314719 PMID:25777084 PMID:25819109 PMID:26172262 PMID:26961604 PMID:29787037 PMID:29908848 PMID:30027469 PMID:30138673 PMID:30172001 PMID:31016361 PMID:31129395 PMID:32407875 PMID:33049310 PMID:37142754 More...
NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356
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PPBP
pro-platelet basic protein
decreases expression
ISO
tributyltin results in decreased expression of PPBP mRNA
CTD
PMID:31129395 PMID:31939706
NCBI chr 4:73,986,439...73,988,190
Ensembl chr 4:73,985,966...73,988,276
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PPM1B
protein phosphatase, Mg2+/Mn2+ dependent 1B
increases expression
ISO
tributyltin results in increased expression of PPM1B mRNA
CTD
PMID:31129395
NCBI chr 2:44,168,875...44,246,928
Ensembl chr 2:44,167,969...44,244,384
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PPP1R3C
protein phosphatase 1 regulatory subunit 3C
decreases expression
ISO
tributyltin results in decreased expression of PPP1R3C mRNA
CTD
PMID:31939706
NCBI chr10:91,628,442...91,633,071
Ensembl chr10:91,628,442...91,633,071
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PPP1R8
protein phosphatase 1 regulatory subunit 8
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of PPP1R8 mRNA
CTD
PMID:31129395
NCBI chr 1:27,830,782...27,851,676
Ensembl chr 1:27,830,782...27,851,676
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PPP2R5A
protein phosphatase 2 regulatory subunit B'alpha
increases expression
ISO
tributyltin results in increased expression of PPP2R5A mRNA
CTD
PMID:24848799
NCBI chr 1:212,285,410...212,361,853
Ensembl chr 1:212,285,410...212,361,853
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PPP4R3A
protein phosphatase 4 regulatory subunit 3A
increases expression
ISO
tributyltin results in increased expression of PPP4R3A mRNA
CTD
PMID:31129395
NCBI chr14:91,457,508...91,510,554
Ensembl chr14:91,457,508...91,510,554
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PPWD1
peptidylprolyl isomerase domain and WD repeat containing 1
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of PPWD1 mRNA
CTD
PMID:31129395
NCBI chr 5:65,563,296...65,587,549
Ensembl chr 5:65,563,236...65,587,549
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PRAMEF20
PRAME family member 20
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of PRAMEF20 mRNA
CTD
PMID:31129395
NCBI chr 1:13,410,450...13,421,328
Ensembl chr 1:13,410,450...13,421,328
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PRDM16
PR/SET domain 16
affects methylation increases expression
EXP ISO
tributyltin affects the methylation of PRDM16 gene tributyltin results in increased expression of PRDM16 mRNA
CTD
PMID:28011154 PMID:31939706
NCBI chr 1:3,069,203...3,438,621
Ensembl chr 1:3,069,168...3,438,621
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PRKCA
protein kinase C alpha
decreases expression
EXP
tributyltin results in decreased expression of PRKCA mRNA
CTD
PMID:27678064
NCBI chr17:66,302,613...66,810,743
Ensembl chr17:66,302,613...66,810,743
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PRKCB
protein kinase C beta
increases expression
EXP
tributyltin results in increased expression of PRKCB mRNA
CTD
PMID:26314263
NCBI chr16:23,835,983...24,220,611
Ensembl chr16:23,835,983...24,220,611
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PRKCD
protein kinase C delta
multiple interactions decreases response to substance
ISO
PRKCD gene mutant form inhibits the reaction [tributyltin results in decreased expression of BAD protein modified form]; PRKCD gene mutant form inhibits the reaction [tributyltin results in decreased expression of BCL2 protein]; PRKCD gene mutant form inhibits the reaction [tributyltin results in decreased expression of BCL2L1 protein]; PRKCD gene mutant form inhibits the reaction [tributyltin results in increased expression of BAX protein]; PRKCD gene mutant form inhibits the reaction [tributyltin results in increased expression of CASP3 protein modified form]; PRKCD gene mutant form promotes the reaction [tributyltin affects the localization of and results in increased activity of NFE2L2 protein]; PRKCD gene mutant form promotes the reaction [tributyltin results in increased expression of GCLC mRNA]; PRKCD gene mutant form promotes the reaction [tributyltin results in increased expression of GCLM mRNA] PRKCD gene mutant form results in decreased susceptibility to tributyltin
CTD
PMID:25895139
NCBI chr 3:53,161,209...53,192,717
Ensembl chr 3:53,156,009...53,192,717
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PRKD1
protein kinase D1
increases phosphorylation
EXP
tributyltin results in increased phosphorylation of PRKD1 protein
CTD
PMID:26228090
NCBI chr14:29,576,479...29,927,847
Ensembl chr14:29,576,479...30,191,898
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PRKD3
protein kinase D3
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of PRKD3 mRNA
CTD
PMID:31129395
NCBI chr 2:37,250,502...37,324,833
Ensembl chr 2:37,250,502...37,324,833
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PROC
protein C, inactivator of coagulation factors Va and VIIIa
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of PROC mRNA
CTD
PMID:31129395
NCBI chr 2:127,418,427...127,429,242
Ensembl chr 2:127,418,427...127,429,242
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PROM1
prominin 1
increases expression
ISO
tributyltin results in increased expression of PROM1 mRNA
CTD
PMID:31939706
NCBI chr 4:15,968,228...16,084,023
Ensembl chr 4:15,963,076...16,084,378
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PRR11
proline rich 11
increases expression
ISO
tributyltin results in increased expression of PRR11 mRNA
CTD
PMID:31939706
NCBI chr17:59,155,746...59,206,709
Ensembl chr17:59,155,732...59,206,709
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PRR15L
proline rich 15 like
increases expression
ISO
tributyltin results in increased expression of PRR15L mRNA
CTD
PMID:31939706
NCBI chr17:47,951,967...47,957,883
Ensembl chr17:47,951,967...47,957,883
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PRR4
proline rich 4
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of PRR4 mRNA
CTD
PMID:31129395
NCBI chr12:10,845,849...10,849,475
Ensembl chr12:10,845,849...10,849,475
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PRRG3
proline rich and Gla domain 3
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of PRRG3 mRNA
CTD
PMID:31129395
NCBI chr X:151,694,607...151,705,924
Ensembl chr X:151,694,607...151,705,924
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PRXL2A
peroxiredoxin like 2A
increases expression
ISO
tributyltin results in increased expression of PRXL2A mRNA
CTD
PMID:24848799
NCBI chr10:80,407,829...80,437,115
Ensembl chr10:80,407,829...80,437,115
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PSMG3
proteasome assembly chaperone 3
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of PSMG3 mRNA
CTD
PMID:31129395
NCBI chr 7:1,567,332...1,570,032
Ensembl chr 7:1,567,332...1,571,005
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PTEN
phosphatase and tensin homolog
increases expression
EXP
tributyltin results in increased expression of PTEN mRNA
CTD
PMID:26314263
NCBI chr10:87,863,625...87,971,930
Ensembl chr10:87,862,638...87,971,930
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PTGR1
prostaglandin reductase 1
increases expression
ISO
tributyltin results in increased expression of PTGR1 mRNA
CTD
PMID:31939706
NCBI chr 9:111,549,722...111,599,647
Ensembl chr 9:111,549,722...111,599,893
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PTGS2
prostaglandin-endoperoxide synthase 2
increases expression
EXP ISO
tributyltin results in increased expression of PTGS2 mRNA tributyltin results in increased expression of PTGS2 protein
CTD
PMID:19371601 PMID:23743147
NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922
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PTPN11
protein tyrosine phosphatase non-receptor type 11
increases expression
EXP
tributyltin results in increased expression of PTPN11 mRNA
CTD
PMID:26314263
NCBI chr12:112,418,947...112,509,918
Ensembl chr12:112,418,351...112,509,918
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PTPRN
protein tyrosine phosphatase receptor type N
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of PTPRN mRNA
CTD
PMID:31129395
NCBI chr 2:219,289,623...219,309,401
Ensembl chr 2:219,289,623...219,309,648
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PTPRT
protein tyrosine phosphatase receptor type T
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of PTPRT mRNA
CTD
PMID:31129395
NCBI chr20:42,031,890...43,189,906
Ensembl chr20:42,072,752...43,189,970
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PXMP4
peroxisomal membrane protein 4
decreases expression
ISO
tributyltin results in decreased expression of PXMP4 mRNA
CTD
PMID:31939706
NCBI chr20:33,702,758...33,720,310
Ensembl chr20:33,702,758...33,720,319
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PYCARD
PYD and CARD domain containing
increases expression
ISO
tributyltin results in increased expression of PYCARD mRNA
CTD
PMID:31939706
NCBI chr16:31,201,486...31,202,760
Ensembl chr16:31,201,486...31,203,450
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RAB24
RAB24, member RAS oncogene family
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of RAB24 mRNA
CTD
PMID:31129395
NCBI chr 5:177,301,198...177,303,719
Ensembl chr 5:177,301,198...177,303,744
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RAB25
RAB25, member RAS oncogene family
increases expression
ISO
tributyltin results in increased expression of RAB25 mRNA
CTD
PMID:31939706
NCBI chr 1:156,061,160...156,070,504
Ensembl chr 1:156,061,160...156,070,504
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RAB37
RAB37, member RAS oncogene family
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of RAB37 mRNA
CTD
PMID:31129395
NCBI chr17:74,671,131...74,747,335
Ensembl chr17:74,670,578...74,747,335
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RAB3B
RAB3B, member RAS oncogene family
increases expression
ISO
tributyltin results in increased expression of RAB3B mRNA
CTD
PMID:21683754
NCBI chr 1:51,907,956...51,990,700
Ensembl chr 1:51,907,956...51,990,700
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RAD18
RAD18 E3 ubiquitin protein ligase
increases expression
ISO
tributyltin results in increased expression of RAD18 mRNA
CTD
PMID:31129395
NCBI chr 3:8,877,075...8,963,472
Ensembl chr 3:8,775,402...8,963,773
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RAF1
Raf-1 proto-oncogene, serine/threonine kinase
multiple interactions
EXP
tributyltin affects the expression of and results in increased phosphorylation of RAF1 protein
CTD
PMID:24038145
NCBI chr 3:12,583,601...12,664,117
Ensembl chr 3:12,582,101...12,664,201
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RARB
retinoic acid receptor beta
increases expression
ISO
tributyltin results in increased expression of RARB mRNA
CTD
PMID:30027469
NCBI chr 3:24,829,321...25,597,932
Ensembl chr 3:24,687,887...25,597,932
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RARG
retinoic acid receptor gamma
increases expression multiple interactions
ISO EXP
tributyltin results in increased expression of RARG mRNA tributyltin results in increased activity of [RARG protein binds to RXRA protein]
CTD
PMID:21683754 PMID:30639747
NCBI chr12:53,210,569...53,232,209
Ensembl chr12:53,210,567...53,232,980
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RARRES2
retinoic acid receptor responder 2
increases expression
ISO
tributyltin results in increased expression of RARRES2 mRNA
CTD
PMID:23428407
NCBI chr 7:150,338,329...150,341,629
Ensembl chr 7:150,338,317...150,341,662
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RASAL2
RAS protein activator like 2
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of RASAL2 mRNA
CTD
PMID:31129395
NCBI chr 1:178,094,104...178,478,850
Ensembl chr 1:178,094,104...178,484,147
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RASD1
ras related dexamethasone induced 1
multiple interactions increases expression
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of RASD1 mRNA tributyltin results in increased expression of RASD1 mRNA
CTD
PMID:31129395
NCBI chr17:17,494,437...17,496,395
Ensembl chr17:17,494,437...17,496,395
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RASGRP1
RAS guanyl releasing protein 1
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of RASGRP1 mRNA
CTD
PMID:31129395
NCBI chr15:38,488,103...38,564,814
Ensembl chr15:38,488,103...38,565,575
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RASSF5
Ras association domain family member 5
increases expression
EXP
tributyltin results in increased expression of RASSF5 mRNA
CTD
PMID:26314263
NCBI chr 1:206,507,531...206,589,448
Ensembl chr 1:206,507,531...206,589,448
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RBBP6
RB binding protein 6, ubiquitin ligase
increases expression
ISO
tributyltin results in increased expression of RBBP6 mRNA
CTD
PMID:31129395
NCBI chr16:24,539,566...24,572,863
Ensembl chr16:24,537,693...24,572,863
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RBPMS
RNA binding protein, mRNA processing factor
increases expression
ISO
tributyltin results in increased expression of RBPMS mRNA
CTD
PMID:24848799
NCBI chr 8:30,384,541...30,572,256
Ensembl chr 8:30,384,511...30,572,256
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REEP6
receptor accessory protein 6
increases expression
ISO
tributyltin results in increased expression of REEP6 mRNA
CTD
PMID:24848799
NCBI chr19:1,491,181...1,497,927
Ensembl chr19:1,491,166...1,497,927
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RELA
RELA proto-oncogene, NF-kB subunit
multiple interactions increases phosphorylation increases expression
ISO EXP
Phycocyanin inhibits the reaction [tributyltin results in increased expression of RELA protein] tributyltin results in increased phosphorylation of RELA protein
CTD
PMID:23743147 PMID:26079211 PMID:30172001 PMID:36319700
NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090
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RETN
resistin
increases expression
ISO
tributyltin results in increased expression of RETN mRNA
CTD
PMID:23428407
NCBI chr19:7,669,049...7,670,455
Ensembl chr19:7,669,049...7,670,455
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RETSAT
retinol saturase
increases expression
ISO
tributyltin results in increased expression of RETSAT mRNA
CTD
PMID:24848799
NCBI chr 2:85,341,955...85,354,528
Ensembl chr 2:85,341,955...85,354,531
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RFLNB
refilin B
increases expression
ISO
tributyltin results in increased expression of RFLNB mRNA
CTD
PMID:31939706
NCBI chr17:439,978...445,940
Ensembl chr17:439,978...445,939
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RFX8
regulatory factor X8
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of RFX8 mRNA
CTD
PMID:31129395
NCBI chr 2:101,397,359...101,475,112
Ensembl chr 2:101,397,359...101,475,112
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RGS3
regulator of G protein signaling 3
multiple interactions increases expression
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of RGS3 mRNA tributyltin results in increased expression of RGS3 mRNA
CTD
PMID:31129395
NCBI chr 9:113,444,730...113,597,738
Ensembl chr 9:113,444,731...113,597,743
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RIC3
RIC3 acetylcholine receptor chaperone
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of RIC3 mRNA
CTD
PMID:31129395
NCBI chr11:8,092,965...8,169,025
Ensembl chr11:8,106,056...8,169,055
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RIMKLB
ribosomal modification protein rimK like family member B
increases expression
ISO
tributyltin results in increased expression of RIMKLB mRNA
CTD
PMID:31129395
NCBI chr12:8,668,638...8,783,091
Ensembl chr12:8,681,600...8,783,095
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RITA1
RBPJ interacting and tubulin associated 1
decreases expression
ISO
tributyltin results in decreased expression of RITA1 mRNA
CTD
PMID:31129395
NCBI chr12:113,185,721...113,192,368
Ensembl chr12:113,185,526...113,192,368
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RLN1
relaxin 1
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of RLN1 mRNA
CTD
PMID:31129395
NCBI chr 9:5,334,930...5,340,916
Ensembl chr 9:5,334,930...5,339,876
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RNF115
ring finger protein 115
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of RNF115 mRNA
CTD
PMID:31129395
NCBI chr 1:145,738,868...145,824,095
Ensembl chr 1:145,738,868...145,824,095
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RNF144A
ring finger protein 144A
decreases expression
ISO
tributyltin results in decreased expression of RNF144A mRNA
CTD
PMID:31939706
NCBI chr 2:6,917,412...7,076,367
Ensembl chr 2:6,917,412...7,068,286
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RNF20
ring finger protein 20
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of RNF20 mRNA
CTD
PMID:31129395
NCBI chr 9:101,533,853...101,563,344
Ensembl chr 9:101,533,853...101,563,344
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RNF212
ring finger protein 212
increases expression
ISO
tributyltin results in increased expression of RNF212 mRNA
CTD
PMID:31129395
NCBI chr 4:1,056,251...1,113,710
Ensembl chr 4:1,056,250...1,113,564
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RNF39
ring finger protein 39
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of RNF39 mRNA
CTD
PMID:31129395
NCBI chr 6:30,070,270...30,075,769
Ensembl chr 6:30,070,266...30,075,849
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ROBO2
roundabout guidance receptor 2
increases expression
ISO
tributyltin results in increased expression of ROBO2 mRNA
CTD
PMID:31129395
NCBI chr 3:75,906,675...77,649,964
Ensembl chr 3:75,906,695...77,649,964
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ROCK1
Rho associated coiled-coil containing protein kinase 1
increases expression
EXP
tributyltin results in increased expression of ROCK1 mRNA
CTD
PMID:26314263
NCBI chr18:20,946,906...21,111,813
Ensembl chr18:20,944,612...21,111,813
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ROCK2
Rho associated coiled-coil containing protein kinase 2
increases expression
EXP
tributyltin results in increased expression of ROCK2 mRNA
CTD
PMID:26314263
NCBI chr 2:11,179,759...11,345,437
Ensembl chr 2:11,179,759...11,348,330
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RPS6
ribosomal protein S6
affects expression
EXP
tributyltin affects the expression of RPS6 protein
CTD
PMID:36372856
NCBI chr 9:19,375,715...19,380,236
Ensembl chr 9:19,375,715...19,380,236
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RPS6KA3
ribosomal protein S6 kinase A3
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of RPS6KA3 mRNA
CTD
PMID:31129395
NCBI chr X:20,149,911...20,267,097
Ensembl chr X:20,149,911...20,267,519
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RPUSD2
RNA pseudouridine synthase domain containing 2
increases expression
ISO
tributyltin results in increased expression of RPUSD2 mRNA
CTD
PMID:31129395
NCBI chr15:40,569,299...40,574,949
Ensembl chr15:40,569,299...40,574,949
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RRM1
ribonucleotide reductase catalytic subunit M1
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of RRM1 mRNA
CTD
PMID:31129395
NCBI chr11:4,094,685...4,138,932
Ensembl chr11:4,094,707...4,138,932
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RRP12
ribosomal RNA processing 12 homolog
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of RRP12 mRNA
CTD
PMID:31129395
NCBI chr10:97,356,357...97,401,370
Ensembl chr10:97,356,357...97,426,076
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RSF1
remodeling and spacing factor 1
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of RSF1 mRNA
CTD
PMID:31129395
NCBI chr11:77,660,009...77,872,232
Ensembl chr11:77,660,009...77,820,869
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RSRC1
arginine and serine rich coiled-coil 1
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of RSRC1 mRNA
CTD
PMID:31129395
NCBI chr 3:158,110,089...158,545,730
Ensembl chr 3:158,105,855...158,545,730
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RTRAF
RNA transcription, translation and transport factor
increases expression
ISO
tributyltin results in increased expression of RTRAF mRNA
CTD
PMID:31129395
NCBI chr14:51,989,546...52,010,694
Ensembl chr14:51,989,514...52,010,694
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RUNX2
RUNX family transcription factor 2
decreases expression
ISO
tributyltin results in decreased expression of RUNX2 mRNA
CTD
PMID:23322813 PMID:24513447 PMID:25777084 PMID:25932594
NCBI chr 6:45,328,330...45,551,082
Ensembl chr 6:45,328,157...45,664,349
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RXRA
retinoid X receptor alpha
multiple interactions decreases response to substance increases expression increases activity
EXP ISO
[tributyltin binds to and results in increased activity of RXRA protein] which results in increased expression of CYP19A1 protein; RXRA protein affects the reaction [tributyltin results in increased expression of and results in increased activity of HSD11B2 protein]; RXRA protein affects the reaction [tributyltin results in increased expression of HSD11B2 mRNA]; RXRA protein affects the reaction [tributyltin results in increased expression of HSD11B2 protein]; tributyltin inhibits the reaction [Alitretinoin binds to RXRA protein]; tributyltin inhibits the reaction [triphenyltin hydroxide binds to RXRA protein]; tributyltin results in increased activity of [RARG protein binds to RXRA protein] RXRA protein mutant form results in decreased susceptibility to tributyltin [bisphenol A co-treated with tributyltin] results in increased expression of RXRA protein tributyltin results in increased expression of RXRA protein tributyltin results in increased expression of RXRA mRNA tributyltin results in increased activity of RXRA protein
CTD
PMID:15941851 PMID:27131391 PMID:29787037 PMID:30027469 PMID:30639747 PMID:31129395 PMID:31927052 More...
NCBI chr 9:134,326,455...134,440,585
Ensembl chr 9:134,317,098...134,440,585
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RXRB
retinoid X receptor beta
multiple interactions increases expression
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of RXRB protein tributyltin results in increased expression of RXRB protein
CTD
PMID:31129395
NCBI chr 6:33,193,588...33,200,853
Ensembl chr 6:33,193,588...33,200,665
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RXRG
retinoid X receptor gamma
increases expression multiple interactions
ISO
tributyltin results in increased expression of RXRG mRNA [bisphenol A co-treated with tributyltin] results in increased expression of RXRG protein tributyltin results in increased expression of RXRG protein
CTD
PMID:23428407 PMID:24848799 PMID:30027469 PMID:31129395
NCBI chr 1:165,400,922...165,445,126
Ensembl chr 1:165,400,922...165,445,355
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S100A6
S100 calcium binding protein A6
increases expression
ISO
tributyltin results in increased expression of S100A6 mRNA
CTD
PMID:21683754
NCBI chr 1:153,534,599...153,535,991
Ensembl chr 1:153,534,599...153,536,244
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S100A8
S100 calcium binding protein A8
increases expression
ISO
tributyltin results in increased expression of S100A8 mRNA
CTD
PMID:31939706
NCBI chr 1:153,390,032...153,422,583
Ensembl chr 1:153,390,032...153,391,073
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SAA1
serum amyloid A1
decreases expression
ISO
tributyltin results in decreased expression of SAA1 mRNA
CTD
PMID:31939706
NCBI chr11:18,266,264...18,269,967
Ensembl chr11:18,266,260...18,269,977
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SAA2
serum amyloid A2
affects expression
ISO
tributyltin affects the expression of SAA2 mRNA
CTD
PMID:31939706
NCBI chr11:18,238,236...18,248,668
Ensembl chr11:18,239,223...18,248,668
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SALL2
spalt like transcription factor 2
increases expression
ISO
tributyltin results in increased expression of SALL2 mRNA
CTD
PMID:31129395
NCBI chr14:21,521,080...21,537,121
Ensembl chr14:21,521,080...21,537,216
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SALL3
spalt like transcription factor 3
decreases expression
ISO
tributyltin results in decreased expression of SALL3 mRNA
CTD
PMID:31129395
NCBI chr18:78,979,818...78,998,969
Ensembl chr18:78,979,818...79,002,677
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SASS6
SAS-6 centriolar assembly protein
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of SASS6 mRNA
CTD
PMID:31129395
NCBI chr 1:100,083,570...100,132,930
Ensembl chr 1:100,083,563...100,132,955
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SCAPER
S-phase cyclin A associated protein in the ER
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of SCAPER mRNA
CTD
PMID:31129395
NCBI chr15:76,347,904...76,905,340
Ensembl chr15:76,347,904...76,905,444
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SCARA5
scavenger receptor class A member 5
decreases expression
ISO
tributyltin results in decreased expression of SCARA5 mRNA
CTD
PMID:31939706
NCBI chr 8:27,869,883...27,992,673
Ensembl chr 8:27,869,883...27,992,673
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SCARB1
scavenger receptor class B member 1
decreases expression
ISO
tributyltin results in decreased expression of SCARB1 mRNA; tributyltin results in decreased expression of SCARB1 protein
CTD
PMID:35430282
NCBI chr12:124,776,856...124,863,864
Ensembl chr12:124,776,856...124,882,668
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SCD5
stearoyl-CoA desaturase 5
increases expression
ISO
tributyltin results in increased expression of SCD3 mRNA
CTD
PMID:23428407
NCBI chr 4:82,629,539...82,798,796
Ensembl chr 4:82,629,539...82,798,796
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SCGB1D4
secretoglobin family 1D member 4
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of SCGB1D4 mRNA
CTD
PMID:31129395
NCBI chr11:62,296,281...62,299,075
Ensembl chr11:62,296,281...62,299,075
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SCN5A
sodium voltage-gated channel alpha subunit 5
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of SCN5A mRNA
CTD
PMID:31129395
NCBI chr 3:38,548,062...38,649,687
Ensembl chr 3:38,548,057...38,649,743
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SCN8A
sodium voltage-gated channel alpha subunit 8
decreases expression
ISO
tributyltin results in decreased expression of SCN8A mRNA
CTD
PMID:31129395
NCBI chr12:51,591,233...51,812,864
Ensembl chr12:51,590,266...51,812,864
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SCN9A
sodium voltage-gated channel alpha subunit 9
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of SCN9A mRNA
CTD
PMID:31129395
NCBI chr 2:166,195,185...166,375,987
Ensembl chr 2:166,195,185...166,376,001
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SCP2
sterol carrier protein 2
increases expression
ISO
tributyltin results in increased expression of SCP2 mRNA
CTD
PMID:23428407
NCBI chr 1:52,927,276...53,051,698
Ensembl chr 1:52,927,276...53,051,698
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SDCBP2
syndecan binding protein 2
increases expression
ISO
tributyltin results in increased expression of SDCBP2 mRNA
CTD
PMID:31939706
NCBI chr20:1,309,909...1,329,139
Ensembl chr20:1,309,909...1,329,139
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SDHB
succinate dehydrogenase complex iron sulfur subunit B
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of SDHB mRNA
CTD
PMID:31129395
NCBI chr 1:17,018,722...17,054,032
Ensembl chr 1:17,018,664...17,054,151
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SEC24B
SEC24 homolog B, COPII coat complex component
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of SEC24B mRNA
CTD
PMID:31129395
NCBI chr 4:109,433,815...109,540,896
Ensembl chr 4:109,433,772...109,540,896
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SEMA3B
semaphorin 3B
increases expression
ISO
tributyltin results in increased expression of SEMA3B mRNA
CTD
PMID:31939706
NCBI chr 3:50,267,652...50,277,546
Ensembl chr 3:50,267,558...50,277,546
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SERPINB1
serpin family B member 1
increases expression
ISO
tributyltin results in increased expression of SERPINB1A mRNA
CTD
PMID:31939706
NCBI chr 6:2,832,332...2,841,863
Ensembl chr 6:2,832,332...2,841,959
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SERTAD3
SERTA domain containing 3
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of SERTAD3 mRNA
CTD
PMID:31129395
NCBI chr19:40,440,844...40,444,335
Ensembl chr19:40,440,844...40,444,335
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SET
SET nuclear proto-oncogene
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of SET protein
CTD
PMID:31129395
NCBI chr 9:128,683,424...128,696,396
Ensembl chr 9:128,683,424...128,696,400
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SETSIP
SET like protein
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of SETSIP mRNA
CTD
PMID:31129395
NCBI chr 1:92,074,533...92,075,411
Ensembl chr 1:92,074,533...92,075,411
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SFN
stratifin
increases expression
ISO
tributyltin results in increased expression of SFN mRNA
CTD
PMID:31939706
NCBI chr 1:26,863,149...26,864,456
Ensembl chr 1:26,863,149...26,864,456
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SGPP2
sphingosine-1-phosphate phosphatase 2
increases expression
ISO
tributyltin results in increased expression of SGPP2 mRNA
CTD
PMID:31939706
NCBI chr 2:222,423,988...222,562,621
Ensembl chr 2:222,424,543...222,562,621
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SH2B2
SH2B adaptor protein 2
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of SH2B2 mRNA
CTD
PMID:31129395
NCBI chr 7:102,285,141...102,321,711
Ensembl chr 7:102,285,091...102,321,711
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SHANK2
SH3 and multiple ankyrin repeat domains 2
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of SHANK2 mRNA
CTD
PMID:31129395
NCBI chr11:70,467,854...71,253,228
Ensembl chr11:70,467,854...71,252,577
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SHBG
sex hormone binding globulin
decreases secretion multiple interactions
ISO
tributyltin results in decreased secretion of SHBG protein [bisphenol A co-treated with tributyltin] results in decreased secretion of SHBG protein
CTD
PMID:31129395
NCBI chr17:7,614,064...7,633,372
Ensembl chr17:7,613,946...7,633,382
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SHISA7
shisa family member 7
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of SHISA7 mRNA
CTD
PMID:31129395
NCBI chr19:55,428,740...55,443,300
Ensembl chr19:55,428,740...55,443,300
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SIGLEC1
sialic acid binding Ig like lectin 1
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of SIGLEC1 mRNA
CTD
PMID:31129395
NCBI chr20:3,686,970...3,712,600
Ensembl chr20:3,686,970...3,712,600
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SIX6
SIX homeobox 6
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of SIX6 mRNA
CTD
PMID:31129395
NCBI chr14:60,509,146...60,512,850
Ensembl chr14:60,509,146...60,512,850
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SLC12A8
solute carrier family 12 member 8
increases expression
ISO
tributyltin results in increased expression of SLC12A8 mRNA
CTD
PMID:31939706
NCBI chr 3:125,082,644...125,212,748
Ensembl chr 3:125,082,636...125,212,864
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SLC13A5
solute carrier family 13 member 5
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of SLC13A5 mRNA
CTD
PMID:31129395
NCBI chr17:6,684,719...6,713,369
Ensembl chr17:6,684,719...6,713,377
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SLC16A3
solute carrier family 16 member 3
increases expression
ISO
tributyltin results in increased expression of SLC16A3 mRNA; tributyltin results in increased expression of SLC16A3 protein
CTD
PMID:21683754 PMID:28993852
NCBI chr17:82,217,934...82,240,086
Ensembl chr17:82,217,934...82,261,129
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SLC16A6
solute carrier family 16 member 6
decreases expression
ISO
tributyltin results in decreased expression of SLC16A6 mRNA
CTD
PMID:31939706
NCBI chr17:68,267,026...68,291,479
Ensembl chr17:68,267,026...68,291,267
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SLC18A2
solute carrier family 18 member A2
multiple interactions
ISO
tributyltin inhibits the reaction [SLC18A2 protein results in increased uptake of Serotonin]
CTD
PMID:1438304
NCBI chr10:117,241,114...117,279,430
Ensembl chr10:117,241,093...117,279,430
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SLC1A5
solute carrier family 1 member 5
increases expression
ISO
tributyltin results in increased expression of SLC1A5 mRNA
CTD
PMID:24848799
NCBI chr19:46,774,883...46,788,594
Ensembl chr19:46,774,883...46,788,594
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SLC1A6
solute carrier family 1 member 6
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of SLC1A6 mRNA
CTD
PMID:31129395
NCBI chr19:14,950,033...15,010,643
Ensembl chr19:14,950,033...15,022,990
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SLC23A3
solute carrier family 23 member 3
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of SLC23A3 mRNA
CTD
PMID:31129395
NCBI chr 2:219,161,465...219,170,029
Ensembl chr 2:219,161,465...219,170,095
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SLC25A20
solute carrier family 25 member 20
increases expression
ISO
tributyltin results in increased expression of SLC25A20 mRNA
CTD
PMID:24848799
NCBI chr 3:48,856,926...48,898,882
Ensembl chr 3:48,856,926...48,898,904
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SLC25A33
solute carrier family 25 member 33
increases expression
ISO
tributyltin results in increased expression of SLC25A33 mRNA
CTD
PMID:24848799
NCBI chr 1:9,539,465...9,585,173
Ensembl chr 1:9,539,465...9,585,173
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SLC26A5
solute carrier family 26 member 5
increases expression
ISO
tributyltin results in increased expression of SLC26A5 mRNA
CTD
PMID:31129395
NCBI chr 7:103,352,730...103,446,207
Ensembl chr 7:103,352,730...103,446,207
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SLC26A6
solute carrier family 26 member 6
increases expression
ISO
tributyltin results in increased expression of SLC26A6 mRNA
CTD
PMID:31939706
NCBI chr 3:48,625,723...48,635,461
Ensembl chr 3:48,625,723...48,635,493
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SLC27A1
solute carrier family 27 member 1
increases expression
ISO
tributyltin results in increased expression of SLC27A1 mRNA
CTD
PMID:23322813
NCBI chr19:17,468,767...17,506,168
Ensembl chr19:17,468,769...17,506,168
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SLC27A6
solute carrier family 27 member 6
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of SLC27A6 mRNA; [bisphenol A co-treated with tributyltin] results in increased expression of SLC27A6 protein
CTD
PMID:31129395
NCBI chr 5:128,965,488...129,033,635
Ensembl chr 5:128,538,013...129,033,642
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SLC28A2
solute carrier family 28 member 2
increases expression
ISO
tributyltin results in increased expression of SLC28A2 mRNA
CTD
PMID:31939706
NCBI chr15:45,252,234...45,277,846
Ensembl chr15:45,252,234...45,277,846
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SLC2A2
solute carrier family 2 member 2
increases expression
EXP
tributyltin results in increased expression of SLC2A2 mRNA
CTD
PMID:35563431
NCBI chr 3:170,996,347...171,026,720
Ensembl chr 3:170,996,347...171,026,743
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SLC2A3
solute carrier family 2 member 3
decreases expression
EXP
tributyltin results in decreased expression of SLC2A3 mRNA
CTD
PMID:19371601
NCBI chr12:7,919,230...7,936,187
Ensembl chr12:7,919,230...8,019,007
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SLC2A4
solute carrier family 2 member 4
decreases expression
ISO
tributyltin results in decreased expression of SLC2A4 protein
CTD
PMID:28397090
NCBI chr17:7,281,718...7,288,257
Ensembl chr17:7,281,718...7,288,257
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SLC2A5
solute carrier family 2 member 5
increases expression
ISO
tributyltin results in increased expression of SLC2A5 mRNA
CTD
PMID:31939706
NCBI chr 1:9,035,106...9,094,195
Ensembl chr 1:9,035,106...9,088,478
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SLC30A4
solute carrier family 30 member 4
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of SLC30A4 mRNA
CTD
PMID:31129395
NCBI chr15:45,479,606...45,522,755
Ensembl chr15:45,479,606...45,522,755
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SLC30A9
solute carrier family 30 member 9
increases expression multiple interactions
ISO
tributyltin results in increased expression of SLC30A9 mRNA [bisphenol A co-treated with tributyltin] results in increased expression of SLC30A9 mRNA
CTD
PMID:31129395
NCBI chr 4:41,990,530...42,090,461
Ensembl chr 4:41,990,502...42,090,461
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SLC34A2
solute carrier family 34 member 2
decreases expression
ISO
tributyltin results in decreased expression of SLC34A2 mRNA
CTD
PMID:31939706
NCBI chr 4:25,655,851...25,678,748
Ensembl chr 4:25,648,011...25,678,748
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SLC37A1
solute carrier family 37 member 1
increases expression
ISO
tributyltin results in increased expression of SLC37A1 mRNA
CTD
PMID:31939706
NCBI chr21:42,499,622...42,581,426
Ensembl chr21:42,496,008...42,581,440
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SLC37A2
solute carrier family 37 member 2
increases expression
ISO
tributyltin results in increased expression of SLC37A2 mRNA
CTD
PMID:31939706
NCBI chr11:125,063,305...125,090,516
Ensembl chr11:125,063,302...125,090,516
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SLC39A5
solute carrier family 39 member 5
increases expression
ISO
tributyltin results in increased expression of SLC39A5 mRNA
CTD
PMID:31939706
NCBI chr12:56,230,051...56,237,846
Ensembl chr12:56,230,049...56,237,846
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SLC3A1
solute carrier family 3 member 1
increases expression
ISO
tributyltin results in increased expression of SLC3A1 mRNA
CTD
PMID:31129395
NCBI chr 2:44,275,480...44,322,437
Ensembl chr 2:44,275,458...44,321,494
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SLC46A2
solute carrier family 46 member 2
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of SLC46A2 mRNA
CTD
PMID:31129395
NCBI chr 9:112,878,920...112,890,876
Ensembl chr 9:112,878,920...112,890,876
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SLC4A7
solute carrier family 4 member 7
increases expression
ISO
tributyltin results in increased expression of SLC4A7 mRNA
CTD
PMID:31939706
NCBI chr 3:27,372,723...27,484,384
Ensembl chr 3:27,372,723...27,484,420
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SLC5A1
solute carrier family 5 member 1
increases expression
ISO
tributyltin results in increased expression of SLC5A1 mRNA
CTD
PMID:31939706
NCBI chr22:32,043,261...32,113,029
Ensembl chr22:32,043,261...32,113,029
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SLC5A6
solute carrier family 5 member 6
increases expression
ISO
tributyltin results in increased expression of SLC5A6 mRNA
CTD
PMID:31939706
NCBI chr 2:27,199,587...27,212,787
Ensembl chr 2:27,199,587...27,212,958
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SLC6A15
solute carrier family 6 member 15
decreases expression
ISO
tributyltin results in decreased expression of SLC6A15 mRNA
CTD
PMID:31129395
NCBI chr12:84,859,491...84,912,799
Ensembl chr12:84,859,491...84,913,629
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SLC7A3
solute carrier family 7 member 3
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of SLC7A3 mRNA
CTD
PMID:31129395
NCBI chr X:70,925,579...70,931,096
Ensembl chr X:70,925,579...70,931,125
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SMIM13
small integral membrane protein 13
decreases expression
ISO
tributyltin results in decreased expression of SMIM13 mRNA
CTD
PMID:31129395
NCBI chr 6:11,093,834...11,138,733
Ensembl chr 6:11,093,834...11,138,733
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SMIM24
small integral membrane protein 24
increases expression
ISO
tributyltin results in increased expression of SMIM24 mRNA
CTD
PMID:31939706
NCBI chr19:3,473,986...3,480,525
Ensembl chr19:3,473,986...3,480,525
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SMPDL3B
sphingomyelin phosphodiesterase acid like 3B
increases expression
ISO
tributyltin results in increased expression of SMPDL3B mRNA
CTD
PMID:31939706
NCBI chr 1:27,935,000...27,959,152
Ensembl chr 1:27,935,000...27,959,157
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SOCS3
suppressor of cytokine signaling 3
decreases expression
ISO
tributyltin results in decreased expression of SOCS3 mRNA
CTD
PMID:31939706
NCBI chr17:78,356,778...78,360,925
Ensembl chr17:78,356,778...78,360,077
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SORBS1
sorbin and SH3 domain containing 1
increases expression
ISO
tributyltin results in increased expression of SORBS1 mRNA
CTD
PMID:23428407
NCBI chr10:95,311,773...95,561,371
Ensembl chr10:95,311,771...95,561,414
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SOX5
SRY-box transcription factor 5
decreases expression
ISO
tributyltin results in decreased expression of SOX5 mRNA
CTD
PMID:24513447
NCBI chr12:23,529,504...24,562,650
Ensembl chr12:23,529,504...24,562,544
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SOX6
SRY-box transcription factor 6
decreases expression
ISO
tributyltin results in decreased expression of SOX6 mRNA
CTD
PMID:24513447
NCBI chr11:15,966,449...16,738,477
Ensembl chr11:15,966,449...16,739,591
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SOX9
SRY-box transcription factor 9
multiple interactions decreases expression
ISO
[tributyltin co-treated with Tetrachlorodibenzodioxin] results in decreased expression of SOX9 mRNA tributyltin results in decreased expression of SOX9 mRNA
CTD
PMID:22749964 PMID:24513447
NCBI chr17:72,121,020...72,126,416
Ensembl chr17:72,121,020...72,126,416
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SP7
Sp7 transcription factor
multiple interactions decreases expression
EXP ISO
tributyltin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA] tributyltin results in decreased expression of SP7 mRNA
CTD
PMID:25777084 PMID:25932594
NCBI chr12:53,326,575...53,344,793
Ensembl chr12:53,326,575...53,345,315
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SPAST
spastin
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of SPAST mRNA
CTD
PMID:31129395
NCBI chr 2:32,063,556...32,157,637
Ensembl chr 2:32,063,556...32,157,637
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SPATA22
spermatogenesis associated 22
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of SPATA22 mRNA
CTD
PMID:31129395
NCBI chr17:3,440,019...3,513,858
Ensembl chr17:3,440,019...3,513,852
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SPHK1
sphingosine kinase 1
decreases expression
EXP
tributyltin results in decreased expression of SPHK1 mRNA
CTD
PMID:26314263
NCBI chr17:76,383,204...76,387,855
Ensembl chr17:76,376,584...76,387,860
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SPINK1
serine peptidase inhibitor Kazal type 1
increases expression
ISO
tributyltin results in increased expression of SPINK1 mRNA
CTD
PMID:31939706
NCBI chr 5:147,824,582...147,839,196
Ensembl chr 5:147,824,572...147,831,671
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SPINT1
serine peptidase inhibitor, Kunitz type 1
increases expression
ISO
tributyltin results in increased expression of SPINT1 mRNA
CTD
PMID:31939706
NCBI chr15:40,844,048...40,858,207
Ensembl chr15:40,844,018...40,858,207
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SPMIP9
sperm microtubule inner protein 9
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of SPMIP9 mRNA
CTD
PMID:31129395
NCBI chr 2:88,524,649...88,529,585
Ensembl chr 2:88,524,649...88,529,585
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SPON2
spondin 2
increases expression
ISO
tributyltin results in increased expression of SPON2 mRNA
CTD
PMID:21683754
NCBI chr 4:1,166,932...1,208,844
Ensembl chr 4:1,166,932...1,208,962
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SPTAN1
spectrin alpha, non-erythrocytic 1
increases cleavage
ISO
tributyltin results in increased cleavage of SPTAN1 protein
CTD
PMID:28707438
NCBI chr 9:128,552,587...128,633,662
Ensembl chr 9:128,552,558...128,633,662
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SPTSSA
serine palmitoyltransferase small subunit A
increases expression
ISO
tributyltin results in increased expression of SPTSSA mRNA
CTD
PMID:31129395
NCBI chr14:34,432,788...34,462,240
Ensembl chr14:34,432,788...34,462,240
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SQSTM1
sequestosome 1
increases expression
EXP ISO
tributyltin results in increased expression of SQSTM1 protein
CTD
PMID:36319700
NCBI chr 5:179,806,393...179,838,078
Ensembl chr 5:179,806,398...179,838,078
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SRC
SRC proto-oncogene, non-receptor tyrosine kinase
affects methylation
EXP
tributyltin affects the methylation of SRC 5' UTR; tributyltin affects the methylation of SRC exon; tributyltin affects the methylation of SRC promoter
CTD
PMID:28011154
NCBI chr20:37,344,699...37,406,050
Ensembl chr20:37,344,685...37,406,050
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SRD5A1
steroid 5 alpha-reductase 1
decreases activity multiple interactions
EXP
tributyltin results in decreased activity of SRD5A1 protein [Finasteride co-treated with tributyltin co-treated with Testosterone] results in increased expression of SRD5A1 mRNA; [tributyltin co-treated with Testosterone] results in increased expression of SRD5A1 mRNA
CTD
PMID:12231121 PMID:23523586
NCBI chr 5:6,633,440...6,674,386
Ensembl chr 5:6,633,290...6,676,539
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SRD5A2
steroid 5 alpha-reductase 2
decreases activity multiple interactions increases expression
EXP ISO
tributyltin results in decreased activity of SRD5A2 protein Finasteride promotes the reaction [tributyltin inhibits the reaction [Testosterone results in increased expression of SRD5A2 mRNA]]; tributyltin inhibits the reaction [Testosterone results in increased expression of SRD5A2 mRNA]; tributyltin promotes the reaction [Finasteride inhibits the reaction [Testosterone results in increased expression of SRD5A2 mRNA]] tributyltin results in increased expression of SRD5A2 mRNA
CTD
PMID:12231121 PMID:21683754 PMID:23523586
NCBI chr 2:31,522,480...31,663,009
Ensembl chr 2:31,522,480...31,580,938
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SREBF1
sterol regulatory element binding transcription factor 1
multiple interactions increases expression
EXP ISO
[tributyltin co-treated with LHB protein] results in increased expression of SREBF1 mRNA; tributyltin promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SREBF1 mRNA] tributyltin results in increased expression of SREBF1 mRNA
CTD
PMID:23322813 PMID:25932594 PMID:28011154 PMID:38630605
NCBI chr17:17,811,334...17,836,986
Ensembl chr17:17,810,399...17,837,002
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SRPX2
sushi repeat containing protein X-linked 2
increases expression
ISO
tributyltin results in increased expression of SRPX2 mRNA
CTD
PMID:21683754
NCBI chr X:100,644,199...100,675,788
Ensembl chr X:100,644,195...100,675,788
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SSNA1
SS nuclear autoantigen 1
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of SSNA1 mRNA
CTD
PMID:31129395
NCBI chr 9:137,188,676...137,190,366
Ensembl chr 9:137,188,660...137,190,370
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ST14
ST14 transmembrane serine protease matriptase
increases expression
ISO
tributyltin results in increased expression of ST14 mRNA
CTD
PMID:31939706
NCBI chr11:130,159,782...130,210,362
Ensembl chr11:130,159,782...130,210,362
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ST3GAL3
ST3 beta-galactoside alpha-2,3-sialyltransferase 3
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of ST3GAL3 mRNA
CTD
PMID:31129395
NCBI chr 1:43,707,536...43,931,159
Ensembl chr 1:43,705,824...43,931,165
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ST7
suppression of tumorigenicity 7
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of ST7 mRNA
CTD
PMID:31129395
NCBI chr 7:116,953,501...117,230,176
Ensembl chr 7:116,953,238...117,230,176
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ST8SIA6
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6
decreases expression
ISO
tributyltin results in decreased expression of ST8SIA6 mRNA
CTD
PMID:31129395
NCBI chr10:17,315,421...17,454,595
Ensembl chr10:17,315,421...17,454,595
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STAR
steroidogenic acute regulatory protein
decreases expression increases expression
ISO EXP
tributyltin results in decreased expression of STAR mRNA; tributyltin results in decreased expression of STAR protein tributyltin results in increased expression of STAR mRNA
CTD
PMID:28707438 PMID:29549738 PMID:31006824 PMID:35430282
NCBI chr 8:38,142,700...38,150,952
Ensembl chr 8:38,142,700...38,150,992
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STEAP4
STEAP4 metalloreductase
decreases expression
ISO
tributyltin results in decreased expression of STEAP4 mRNA
CTD
PMID:31939706
NCBI chr 7:88,270,892...88,306,894
Ensembl chr 7:88,270,892...88,306,894
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STK31
serine/threonine kinase 31
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of STK31 mRNA
CTD
PMID:31129395
NCBI chr 7:23,710,082...23,832,513
Ensembl chr 7:23,710,203...23,832,513
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STOX1
storkhead box 1
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of STOX1 mRNA
CTD
PMID:31129395
NCBI chr10:68,827,531...68,895,432
Ensembl chr10:68,827,531...68,895,432
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STRC
stereocilin
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of STRC mRNA
CTD
PMID:31129395
NCBI chr15:43,599,563...43,618,800
Ensembl chr15:43,599,563...43,618,800
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SUCLG1
succinate-CoA ligase GDP/ADP-forming subunit alpha
increases expression
ISO
tributyltin results in increased expression of SUCLG1 mRNA
CTD
PMID:23428407
NCBI chr 2:84,423,528...84,459,280
Ensembl chr 2:84,423,528...84,460,045
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SULT1C2
sulfotransferase family 1C member 2
increases expression
ISO
tributyltin results in increased expression of SULT1C2 mRNA
CTD
PMID:31939706
NCBI chr 2:108,288,895...108,309,915
Ensembl chr 2:108,288,639...108,309,915
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SULT2B1
sulfotransferase family 2B member 1
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of SULT2B1 mRNA
CTD
PMID:31129395
NCBI chr19:48,552,172...48,599,427
Ensembl chr19:48,552,172...48,599,425
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SV2B
synaptic vesicle glycoprotein 2B
increases expression
ISO
tributyltin results in increased expression of SV2B mRNA
CTD
PMID:21683754
NCBI chr15:91,099,588...91,302,565
Ensembl chr15:91,099,950...91,302,565
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SYBU
syntabulin
decreases expression
ISO
tributyltin results in decreased expression of SYBU mRNA
CTD
PMID:31939706
NCBI chr 8:109,573,978...109,691,600
Ensembl chr 8:109,573,978...109,691,791
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SYK
spleen associated tyrosine kinase
increases expression
EXP
tributyltin results in increased expression of SYK mRNA
CTD
PMID:26314263
NCBI chr 9:90,801,600...90,898,549
Ensembl chr 9:90,801,787...90,898,549
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SYNPO2
synaptopodin 2
increases expression
ISO
tributyltin results in increased expression of SYNPO2 mRNA
CTD
PMID:31939706
NCBI chr 4:118,850,681...119,061,247
Ensembl chr 4:118,850,688...119,061,247
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SYT12
synaptotagmin 12
decreases expression
ISO
tributyltin results in decreased expression of SYT12 mRNA
CTD
PMID:31939706
NCBI chr11:67,006,771...67,050,863
Ensembl chr11:67,006,778...67,050,863
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SYT4
synaptotagmin 4
increases expression
ISO
tributyltin results in increased expression of SYT4 mRNA
CTD
PMID:21683754
NCBI chr18:43,267,892...43,277,490
Ensembl chr18:43,267,892...43,277,535
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SYTL4
synaptotagmin like 4
multiple interactions decreases expression
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of SYTL4 mRNA tributyltin results in decreased expression of SYTL4 mRNA
CTD
PMID:31129395
NCBI chr X:100,674,491...100,732,121
Ensembl chr X:100,671,783...100,732,123
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TACC2
transforming acidic coiled-coil containing protein 2
decreases expression
ISO
tributyltin results in decreased expression of TACC2 mRNA
CTD
PMID:31939706
NCBI chr10:121,989,163...122,254,542
Ensembl chr10:121,989,163...122,254,545
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TAF1A
TATA-box binding protein associated factor, RNA polymerase I subunit A
increases expression multiple interactions
ISO
tributyltin results in increased expression of TAF1A mRNA [bisphenol A co-treated with tributyltin] results in increased expression of TAF1A mRNA
CTD
PMID:31129395
NCBI chr 1:222,554,105...222,589,933
Ensembl chr 1:222,557,902...222,589,933
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TANGO6
transport and golgi organization 6 homolog
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of TANGO6 mRNA
CTD
PMID:31129395
NCBI chr16:68,843,531...69,085,182
Ensembl chr16:68,843,531...69,085,182
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TAS2R60
taste 2 receptor member 60
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of TAS2R135 mRNA
CTD
PMID:31129395
NCBI chr 7:143,443,453...143,444,409
Ensembl chr 7:143,443,453...143,444,409
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TASOR2
transcription activation suppressor family member 2
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of TASOR2 mRNA
CTD
PMID:31129395
NCBI chr10:5,684,838...5,763,740
Ensembl chr10:5,684,731...5,763,779
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TBX20
T-box transcription factor 20
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of TBX20 mRNA
CTD
PMID:31129395
NCBI chr 7:35,202,430...35,254,100
Ensembl chr 7:35,202,430...35,254,100
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TCF23
transcription factor 23
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of TCF23 mRNA
CTD
PMID:31129395
NCBI chr 2:27,149,004...27,156,974
Ensembl chr 2:27,149,004...27,156,974
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TECPR1
tectonin beta-propeller repeat containing 1
increases expression
ISO
tributyltin results in increased expression of TECPR1 mRNA
CTD
PMID:21683754
NCBI chr 7:98,214,624...98,252,232
Ensembl chr 7:98,214,624...98,252,232
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TEF
TEF transcription factor, PAR bZIP family member
increases expression
ISO
tributyltin results in increased expression of TEF mRNA
CTD
PMID:31939706
NCBI chr22:41,367,455...41,399,326
Ensembl chr22:41,367,333...41,399,326
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TERT
telomerase reverse transcriptase
increases expression
ISO
tributyltin results in increased expression of TERT mRNA
CTD
PMID:31939706
NCBI chr 5:1,253,167...1,295,068
Ensembl chr 5:1,253,147...1,295,068
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TESMIN
testis expressed metallothionein like protein
decreases expression
ISO
tributyltin results in decreased expression of TESMIN protein
CTD
PMID:24055800 PMID:28707438
NCBI chr11:68,704,796...68,751,520
Ensembl chr11:68,707,440...68,751,520
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TEX38
testis expressed 38
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of TEX38 mRNA
CTD
PMID:31129395
NCBI chr 1:46,668,886...46,673,594
Ensembl chr 1:46,668,855...46,673,594
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TF
transferrin
increases expression
ISO
tributyltin results in increased expression of TF mRNA
CTD
PMID:21683754
NCBI chr 3:133,661,998...133,796,641
Ensembl chr 3:133,746,040...133,796,641
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TFRC
transferrin receptor
increases expression
ISO
tributyltin results in increased expression of TFRC mRNA
CTD
PMID:24848799
NCBI chr 3:196,049,284...196,082,090
Ensembl chr 3:196,012,511...196,082,153
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TGFA
transforming growth factor alpha
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of TGFA mRNA
CTD
PMID:31129395
NCBI chr 2:70,447,284...70,553,826
Ensembl chr 2:70,447,284...70,554,193
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TGFB1
transforming growth factor beta 1
increases expression
EXP ISO
tributyltin results in increased expression of TGFB1 mRNA
CTD
PMID:36319700
NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922
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TGM2
transglutaminase 2
multiple interactions increases expression
ISO
diazepinylbenzoic acid inhibits the reaction [tributyltin results in increased expression of TGM2 mRNA]
CTD
PMID:21622945 PMID:25932594
NCBI chr20:38,127,385...38,168,475
Ensembl chr20:38,127,385...38,166,578
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THRA
thyroid hormone receptor alpha
multiple interactions
EXP
tributyltin binds to and results in increased activity of THRA protein
CTD
PMID:33049310
NCBI chr17:40,062,193...40,093,867
Ensembl chr17:40,058,290...40,093,867
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THRB
thyroid hormone receptor beta
increases expression multiple interactions
ISO EXP
tributyltin results in increased expression of THRB mRNA tributyltin binds to and results in increased activity of THRB protein
CTD
PMID:30027469 PMID:33049310
NCBI chr 3:24,117,153...24,495,708
Ensembl chr 3:24,117,153...24,495,756
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THRSP
thyroid hormone responsive
increases expression
ISO
tributyltin results in increased expression of THRSP mRNA
CTD
PMID:21683754
NCBI chr11:78,063,861...78,068,351
Ensembl chr11:78,063,861...78,068,351
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THY1
Thy-1 cell surface antigen
decreases expression
EXP
tributyltin results in decreased expression of THY1 mRNA
CTD
PMID:26314263
NCBI chr11:119,415,476...119,424,985
Ensembl chr11:119,415,476...119,424,985
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TJP1
tight junction protein 1
multiple interactions decreases expression
ISO
Acetylcysteine inhibits the reaction [tributyltin results in decreased expression of TJP1 protein]
CTD
PMID:26079211
NCBI chr15:29,699,367...29,969,049
Ensembl chr15:29,699,367...29,968,915
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TLCD4
TLC domain containing 4
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of TLCD4 mRNA
CTD
PMID:31129395
NCBI chr 1:95,092,517...95,197,607
Ensembl chr 1:95,117,355...95,197,607
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TLE7
TLE family member 7
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of TLE7 mRNA
CTD
PMID:31129395
NCBI chr16:71,429,980...71,442,054
Ensembl chr16:71,429,980...71,442,054
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TM4SF20
transmembrane 4 L six family member 20
increases expression
ISO
tributyltin results in increased expression of TM4SF20 mRNA
CTD
PMID:31939706
NCBI chr 2:227,362,038...227,381,647
Ensembl chr 2:227,362,038...227,381,995
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TMC4
transmembrane channel like 4
increases expression
ISO
tributyltin results in increased expression of TMC4 mRNA
CTD
PMID:31939706
NCBI chr19:54,160,108...54,173,160
Ensembl chr19:54,160,108...54,173,250
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TMEM106A
transmembrane protein 106A
increases expression
ISO
tributyltin results in increased expression of TMEM106A mRNA
CTD
PMID:21683754
NCBI chr17:43,211,875...43,220,041
Ensembl chr17:43,211,835...43,220,041
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TMEM128
transmembrane protein 128
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of TMEM128 mRNA
CTD
PMID:31129395
NCBI chr 4:4,235,542...4,248,223
Ensembl chr 4:4,235,542...4,248,223
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TMEM171
transmembrane protein 171
decreases expression
ISO
tributyltin results in decreased expression of TMEM171 mRNA
CTD
PMID:31129395
NCBI chr 5:73,120,575...73,131,809
Ensembl chr 5:73,120,569...73,131,809
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TMEM213
transmembrane protein 213
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of TMEM213 mRNA
CTD
PMID:31129395
NCBI chr 7:138,797,994...138,806,759
Ensembl chr 7:138,797,952...138,838,101
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TMEM45B
transmembrane protein 45B
increases expression
ISO
tributyltin results in increased expression of TMEM45B mRNA
CTD
PMID:31939706
NCBI chr11:129,815,848...129,860,003
Ensembl chr11:129,815,848...129,860,003
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TMEM71
transmembrane protein 71
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of TMEM71 mRNA
CTD
PMID:31129395
NCBI chr 8:132,705,839...132,775,999
Ensembl chr 8:132,685,007...132,760,712
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TMEM91
transmembrane protein 91
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of TMEM91 mRNA
CTD
PMID:31129395
NCBI chr19:41,363,947...41,384,083
Ensembl chr19:41,350,911...41,384,083
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TMOD1
tropomodulin 1
increases expression
ISO
tributyltin results in increased expression of TMOD1 mRNA
CTD
PMID:21683754
NCBI chr 9:97,501,180...97,601,743
Ensembl chr 9:97,501,180...97,601,743
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TMPRSS4
transmembrane serine protease 4
increases expression
ISO
tributyltin results in increased expression of TMPRSS4 mRNA
CTD
PMID:31939706
NCBI chr11:118,077,078...118,125,505
Ensembl chr11:118,077,012...118,125,510
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TMX3
thioredoxin related transmembrane protein 3
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of TMX3 mRNA
CTD
PMID:31129395
NCBI chr18:68,673,688...68,715,108
Ensembl chr18:68,673,688...68,715,108
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TNF
tumor necrosis factor
multiple interactions affects expression increases expression
EXP ISO
4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [tributyltin results in increased expression of and results in increased secretion of TNF protein]; batimastat inhibits the reaction [tributyltin results in increased secretion of TNF protein]; tributyltin affects the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; tributyltin results in increased expression of and results in increased secretion of TNF protein tributyltin affects the expression of TNF mRNA tributyltin results in increased expression of TNF mRNA tributyltin results in increased expression of TNF protein
CTD
PMID:17092623 PMID:29532501 PMID:30172001 PMID:36319700
NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
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TNFRSF10D
TNF receptor superfamily member 10d
decreases expression
EXP
tributyltin results in decreased expression of TNFRSF10D mRNA
CTD
PMID:27678064
NCBI chr 8:23,135,588...23,164,027
Ensembl chr 8:23,135,588...23,164,027
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TNFRSF11B
TNF receptor superfamily member 11b
multiple interactions
EXP ISO
tributyltin promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in decreased secretion of TNFRSF11B protein] [bisphenol A co-treated with tributyltin] results in increased expression of TNFRSF11B mRNA
CTD
PMID:31016361 PMID:31129395
NCBI chr 8:118,923,557...118,951,885
Ensembl chr 8:118,923,557...118,951,885
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TNFRSF19
TNF receptor superfamily member 19
increases expression
ISO
tributyltin results in increased expression of TNFRSF19 mRNA
CTD
PMID:31939706
NCBI chr13:23,570,412...23,676,093
Ensembl chr13:23,570,370...23,676,104
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TNFRSF9
TNF receptor superfamily member 9
decreases expression
ISO
tributyltin results in decreased expression of TNFRSF9 mRNA
CTD
PMID:31129395
NCBI chr 1:7,915,871...7,940,839
Ensembl chr 1:7,915,871...7,943,165
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TNFSF11
TNF superfamily member 11
multiple interactions
ISO
Ro 41-5253 inhibits the reaction [tributyltin inhibits the reaction [TNFSF11 protein results in increased expression of NFATC1 protein]]; tributyltin inhibits the reaction [TNFSF11 protein results in increased expression of NFATC1 protein]
CTD
PMID:17291456
NCBI chr13:42,562,736...42,608,013
Ensembl chr13:42,562,736...42,608,013
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TOGARAM1
TOG array regulator of axonemal microtubules 1
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of TOGARAM1 mRNA
CTD
PMID:31129395
NCBI chr14:44,962,190...45,074,431
Ensembl chr14:44,962,190...45,074,431
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TOR3A
torsin family 3 member A
decreases expression
ISO
tributyltin results in decreased expression of TOR3A mRNA
CTD
PMID:31939706
NCBI chr 1:179,082,070...179,095,996
Ensembl chr 1:179,082,070...179,098,023
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TOX4
TOX high mobility group box family member 4
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of TOX4 mRNA
CTD
PMID:31129395
NCBI chr14:21,477,195...21,499,170
Ensembl chr14:21,476,597...21,499,175
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TP53
tumor protein p53
increases expression multiple interactions decreases expression
EXP ISO
tributyltin results in increased expression of TP53 protein 2-(2,6-dimethylmorpholin-4-yl)-N-(5-(6-morpholin-4-yl-4-oxo-4H-pyran-2-yl)-9H-thioxanthen-2-yl)acetamide inhibits the reaction [tributyltin results in increased expression of TP53 protein]; pyrazolanthrone inhibits the reaction [tributyltin results in increased expression of TP53 protein] tributyltin results in increased expression of TRP53 protein tributyltin results in decreased expression of TP53 protein
CTD
PMID:25743928 PMID:26961604 PMID:33720505 PMID:36319700
NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546
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TP53INP2
tumor protein p53 inducible nuclear protein 2
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of TP53INP2 mRNA
CTD
PMID:31129395
NCBI chr20:34,704,344...34,713,436
Ensembl chr20:34,704,339...34,713,439
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TPST1
tyrosylprotein sulfotransferase 1
multiple interactions increases expression
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of TPST1 mRNA tributyltin results in increased expression of TPST1 mRNA
CTD
PMID:31129395
NCBI chr 7:66,198,790...66,360,443
Ensembl chr 7:66,205,317...66,420,543
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TRANK1
tetratricopeptide repeat and ankyrin repeat containing 1
decreases expression
ISO
tributyltin results in decreased expression of TRANK1 mRNA
CTD
PMID:31129395
NCBI chr 3:36,826,819...36,945,744
Ensembl chr 3:36,826,819...36,945,057
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TREH
trehalase
increases expression
ISO
tributyltin results in increased expression of TREH mRNA
CTD
PMID:31939706
NCBI chr11:118,657,316...118,679,650
Ensembl chr11:118,657,316...118,679,690
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TRIB3
tribbles pseudokinase 3
increases expression
ISO
tributyltin results in increased expression of TRIB3 mRNA
CTD
PMID:21683754
NCBI chr20:380,760...397,559
Ensembl chr20:362,835...397,559
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TRIM47
tripartite motif containing 47
increases expression
ISO
tributyltin results in increased expression of TRIM47 mRNA
CTD
PMID:21683754
NCBI chr17:75,874,164...75,878,581
Ensembl chr17:75,874,164...75,878,581
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TRIM71
tripartite motif containing 71
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of TRIM71 mRNA
CTD
PMID:31129395
NCBI chr 3:32,817,997...32,897,824
Ensembl chr 3:32,817,997...32,897,824
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TRPM4
transient receptor potential cation channel subfamily M member 4
increases expression
ISO
tributyltin results in increased expression of TRPM4 mRNA
CTD
PMID:31939706
NCBI chr19:49,157,792...49,211,836
Ensembl chr19:49,157,741...49,211,836
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TRPV1
transient receptor potential cation channel subfamily V member 1
decreases expression
ISO
tributyltin results in decreased expression of TRPV1 mRNA
CTD
PMID:31129395
NCBI chr17:3,565,446...3,609,411
Ensembl chr17:3,565,444...3,609,411
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TSC22D3
TSC22 domain family member 3
decreases expression
EXP
tributyltin results in decreased expression of TSC22D3 mRNA
CTD
PMID:28011154
NCBI chr X:107,713,221...107,775,988
Ensembl chr X:107,713,221...107,777,342
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TSPAN15
tetraspanin 15
increases expression
ISO
tributyltin results in increased expression of TSPAN15 mRNA
CTD
PMID:31939706
NCBI chr10:69,451,465...69,549,508
Ensembl chr10:69,451,465...69,507,666
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TSPAN3
tetraspanin 3
increases expression
ISO
tributyltin results in increased expression of TSPAN3 mRNA
CTD
PMID:31939706
NCBI chr15:77,041,404...77,071,109
Ensembl chr15:77,041,404...77,083,984
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TSPAN8
tetraspanin 8
increases expression
ISO
tributyltin results in increased expression of TSPAN8 mRNA
CTD
PMID:31939706
NCBI chr12:71,125,096...71,157,999
Ensembl chr12:71,125,085...71,441,898
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TSPO
translocator protein
increases expression affects expression
ISO
tributyltin results in increased expression of TSPO mRNA tributyltin affects the expression of TSPO protein
CTD
PMID:21683754 PMID:28707438
NCBI chr22:43,151,559...43,163,242
Ensembl chr22:43,151,547...43,163,242
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TTC21A
tetratricopeptide repeat domain 21A
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of TTC21A mRNA
CTD
PMID:31129395
NCBI chr 3:39,107,680...39,138,900
Ensembl chr 3:39,107,680...39,138,903
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TTL
tubulin tyrosine ligase
multiple interactions decreases expression
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of TTL mRNA tributyltin results in decreased expression of TTL mRNA
CTD
PMID:31129395
NCBI chr 2:112,482,156...112,541,739
Ensembl chr 2:112,482,156...112,541,739
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TUBB1
tubulin beta 1 class VI
decreases expression
ISO
tributyltin results in decreased expression of TUBB1 mRNA
CTD
PMID:31939706
NCBI chr20:59,016,438...59,026,654
Ensembl chr20:59,019,429...59,026,654
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TUBB2A
tubulin beta 2A class IIa
decreases expression
ISO
tributyltin results in decreased expression of TUBB2A mRNA
CTD
PMID:31939706
NCBI chr 6:3,153,666...3,157,544
Ensembl chr 6:3,153,497...3,157,544
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TUBB3
tubulin beta 3 class III
multiple interactions increases degradation
ISO
CAST protein inhibits the reaction [tributyltin results in increased degradation of TUBB3 protein]
CTD
PMID:33481012
NCBI chr16:89,921,925...89,936,097
Ensembl chr16:89,921,392...89,938,761
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TUBB6
tubulin beta 6 class V
decreases expression
ISO
tributyltin results in decreased expression of TUBB6 mRNA
CTD
PMID:31939706
NCBI chr18:12,307,669...12,329,826
Ensembl chr18:12,307,669...12,344,320
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TUBG1
tubulin gamma 1
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of TUBG1 mRNA
CTD
PMID:31129395
NCBI chr17:42,609,683...42,615,238
Ensembl chr17:42,609,641...42,615,238
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TUBGCP3
tubulin gamma complex component 3
decreases expression
ISO
tributyltin results in decreased expression of TUBGCP3 mRNA
CTD
PMID:31129395
NCBI chr13:112,485,011...112,605,630
Ensembl chr13:112,485,011...112,588,205
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TWIST1
twist family bHLH transcription factor 1
multiple interactions decreases expression
ISO
Tetrachlorodibenzodioxin promotes the reaction [tributyltin results in decreased expression of TWIST1 mRNA]
CTD
PMID:22749964
NCBI chr 7:19,113,047...19,117,636
Ensembl chr 7:19,020,991...19,117,636
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TXNIP
thioredoxin interacting protein
increases expression
ISO
tributyltin results in increased expression of TXNIP mRNA
CTD
PMID:21683754
NCBI chr 1:145,992,435...145,996,579
Ensembl chr 1:145,992,435...145,996,579
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TYW3
tRNA-yW synthesizing protein 3 homolog
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of TYW3 mRNA
CTD
PMID:31129395
NCBI chr 1:74,733,152...74,766,677
Ensembl chr 1:74,733,152...74,766,678
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UACA
uveal autoantigen with coiled-coil domains and ankyrin repeats
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of UACA mRNA
CTD
PMID:31129395
NCBI chr15:70,654,554...70,778,903
Ensembl chr15:70,654,554...70,763,558
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UBR1
ubiquitin protein ligase E3 component n-recognin 1
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of UBR1 mRNA
CTD
PMID:31129395
NCBI chr15:42,942,897...43,106,038
Ensembl chr15:42,942,897...43,106,113
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UCP1
uncoupling protein 1
increases expression
ISO
tributyltin results in increased expression of UCP1 mRNA
CTD
PMID:21683088
NCBI chr 4:140,559,431...140,568,961
Ensembl chr 4:140,559,431...140,568,961
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UCP2
uncoupling protein 2
increases expression
ISO
tributyltin results in increased expression of UCP2 mRNA
CTD
PMID:23428407
NCBI chr11:73,974,672...73,983,202
Ensembl chr11:73,974,061...73,982,843
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UGT1A5
UDP glucuronosyltransferase family 1 member A5
increases expression
ISO
tributyltin results in increased expression of UGT1A5 mRNA
CTD
PMID:21683754
NCBI chr 2:233,712,907...233,773,300
Ensembl chr 2:233,712,907...233,773,300
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UNC119B
unc-119 lipid binding chaperone B
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of UNC119B mRNA
CTD
PMID:31129395
NCBI chr12:120,710,458...120,723,640
Ensembl chr12:120,710,458...120,723,640
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UNC5D
unc-5 netrin receptor D
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of UNC5D mRNA
CTD
PMID:31129395
NCBI chr 8:35,235,475...35,796,540
Ensembl chr 8:35,235,475...35,796,550
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UPK2
uroplakin 2
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of UPK2 mRNA
CTD
PMID:31129395
NCBI chr11:118,956,298...118,958,559
Ensembl chr11:118,925,164...118,958,559
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UPP1
uridine phosphorylase 1
increases expression
ISO
tributyltin results in increased expression of UPP1 mRNA
CTD
PMID:31939706
NCBI chr 7:48,088,704...48,108,736
Ensembl chr 7:48,088,628...48,108,736
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UPP2
uridine phosphorylase 2
increases expression
ISO
tributyltin results in increased expression of UPP2 mRNA
CTD
PMID:31939706
NCBI chr 2:157,995,179...158,136,154
Ensembl chr 2:157,876,679...158,136,154
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USP2
ubiquitin specific peptidase 2
increases expression
ISO
tributyltin results in increased expression of USP2 mRNA
CTD
PMID:31939706
NCBI chr11:119,355,215...119,381,690
Ensembl chr11:119,355,215...119,381,711
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USP43
ubiquitin specific peptidase 43
increases expression
ISO
tributyltin results in increased expression of USP43 mRNA
CTD
PMID:31939706
NCBI chr17:9,645,260...9,729,687
Ensembl chr17:9,644,698...9,729,687
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VAV3
vav guanine nucleotide exchange factor 3
increases expression
EXP
tributyltin results in increased expression of VAV3 mRNA
CTD
PMID:26314263
NCBI chr 1:107,571,161...107,965,180
Ensembl chr 1:107,571,161...107,965,180
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VDR
vitamin D receptor
decreases expression
ISO
tributyltin results in decreased expression of VDR mRNA
CTD
PMID:30027469
NCBI chr12:47,841,537...47,904,994
Ensembl chr12:47,841,537...47,943,048
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VIL1
villin 1
increases expression
ISO
tributyltin results in increased expression of VIL1 mRNA
CTD
PMID:31939706
NCBI chr 2:218,419,123...218,453,295
Ensembl chr 2:218,419,121...218,453,295
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VIM
vimentin
decreases expression multiple interactions
EXP
tributyltin results in decreased expression of VIM mRNA; tributyltin results in decreased expression of VIM protein Tretinoin promotes the reaction [tributyltin results in decreased expression of VIM mRNA]; Tretinoin promotes the reaction [tributyltin results in decreased expression of VIM protein]
CTD
PMID:30806631 PMID:31634547
NCBI chr10:17,228,241...17,237,593
Ensembl chr10:17,228,241...17,237,593
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VPREB1
V-set pre-B cell surrogate light chain 1
increases expression
EXP
tributyltin results in increased expression of VPREB1 mRNA
CTD
PMID:24356939
NCBI chr22:22,244,786...22,245,515
Ensembl chr22:22,244,780...22,245,515
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VSX1
visual system homeobox 1
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of VSX1 mRNA
CTD
PMID:31129395
NCBI chr20:25,070,880...25,082,141
Ensembl chr20:25,070,885...25,082,141
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WDR3
WD repeat domain 3
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of WDR3 mRNA
CTD
PMID:31129395
NCBI chr 1:117,929,739...117,966,543
Ensembl chr 1:117,929,720...117,966,543
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WDR91
WD repeat domain 91
increases expression
ISO
tributyltin results in increased expression of WDR91 mRNA
CTD
PMID:31129395
NCBI chr 7:135,183,839...135,211,526
Ensembl chr 7:135,183,839...135,211,555
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WEE1
WEE1 G2 checkpoint kinase
increases expression
ISO
tributyltin results in increased expression of WEE1 mRNA
CTD
PMID:31939706
NCBI chr11:9,573,670...9,589,985
Ensembl chr11:9,573,670...9,593,457
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WNT5A
Wnt family member 5A
decreases expression
EXP
tributyltin results in decreased expression of WNT5A mRNA
CTD
PMID:28011154
NCBI chr 3:55,465,715...55,505,263
Ensembl chr 3:55,465,715...55,490,539
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WRNIP1
WRN helicase interacting protein 1
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of WRNIP1 mRNA
CTD
PMID:31129395
NCBI chr 6:2,765,393...2,786,952
Ensembl chr 6:2,765,393...2,786,952
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XBP1
X-box binding protein 1
increases splicing
EXP
tributyltin results in increased splicing of XBP1 mRNA
CTD
PMID:23743301
NCBI chr22:28,794,560...28,800,569
Ensembl chr22:28,794,555...28,800,597
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XPA
XPA, DNA damage recognition and repair factor
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of XPA mRNA
CTD
PMID:31129395
NCBI chr 9:97,654,398...97,697,340
Ensembl chr 9:97,674,909...97,697,340
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YPEL2
yippee like 2
decreases expression
ISO
tributyltin results in decreased expression of YPEL2 mRNA
CTD
PMID:31939706
NCBI chr17:59,331,655...59,401,729
Ensembl chr17:59,331,655...59,401,729
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ZBTB16
zinc finger and BTB domain containing 16
decreases expression
ISO
tributyltin results in decreased expression of ZBTB16 mRNA
CTD
PMID:31939706
NCBI chr11:114,059,711...114,256,770
Ensembl chr11:114,059,041...114,256,765
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ZBTB39
zinc finger and BTB domain containing 39
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of ZBTB39 mRNA
CTD
PMID:31129395
NCBI chr12:56,998,836...57,006,546
Ensembl chr12:56,998,836...57,006,546
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ZBTB7B
zinc finger and BTB domain containing 7B
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of ZBTB7B mRNA
CTD
PMID:31129395
NCBI chr 1:155,001,750...155,018,523
Ensembl chr 1:155,002,630...155,018,523
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ZBTB7C
zinc finger and BTB domain containing 7C
decreases expression
ISO
tributyltin results in decreased expression of ZBTB7C mRNA
CTD
PMID:31939706
NCBI chr18:48,026,672...48,412,585
Ensembl chr18:48,026,672...48,410,752
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ZDHHC2
zinc finger DHHC-type palmitoyltransferase 2
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of ZDHHC2 mRNA
CTD
PMID:31129395
NCBI chr 8:17,156,482...17,224,799
Ensembl chr 8:17,156,482...17,224,799
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ZFP36
ZFP36 ring finger protein
increases expression
ISO
tributyltin results in increased expression of ZFP36 mRNA
CTD
PMID:21683754
NCBI chr19:39,406,847...39,409,407
Ensembl chr19:39,406,847...39,409,407
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ZKSCAN1
zinc finger with KRAB and SCAN domains 1
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of ZKSCAN1 mRNA
CTD
PMID:31129395
NCBI chr 7:100,015,596...100,045,374
Ensembl chr 7:100,015,572...100,041,689
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ZKSCAN7
zinc finger with KRAB and SCAN domains 7
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of ZKSCAN7 mRNA
CTD
PMID:31129395
NCBI chr 3:44,555,193...44,583,483
Ensembl chr 3:44,555,193...44,594,173
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ZMAT1
zinc finger matrin-type 1
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of ZMAT1 mRNA
CTD
PMID:31129395
NCBI chr X:101,882,290...101,932,027
Ensembl chr X:101,882,288...101,932,031
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ZNF24
zinc finger protein 24
decreases expression
ISO
tributyltin results in decreased expression of ZFP24 mRNA
CTD
PMID:31129395
NCBI chr18:35,332,227...35,344,420
Ensembl chr18:35,332,227...35,345,482
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ZNF281
zinc finger protein 281
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of ZFP281 mRNA
CTD
PMID:31129395
NCBI chr 1:200,404,951...200,410,036
Ensembl chr 1:200,404,940...200,410,056
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ZNF423
zinc finger protein 423
increases expression
ISO
tributyltin results in increased expression of ZFP423 mRNA
CTD
PMID:23322813
NCBI chr16:49,487,524...49,859,279
Ensembl chr16:49,487,524...49,857,919
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ZNF569
zinc finger protein 569
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in decreased expression of ZFP74 mRNA
CTD
PMID:31129395
NCBI chr19:37,411,157...37,469,265
Ensembl chr19:37,411,155...37,469,275
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ZNF800
zinc finger protein 800
multiple interactions
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of ZFP800 mRNA
CTD
PMID:31129395
NCBI chr 7:127,342,859...127,392,708
Ensembl chr 7:127,346,790...127,431,924
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ZNF84
zinc finger protein 84
multiple interactions increases expression
ISO
[bisphenol A co-treated with tributyltin] results in increased expression of ZFP300 mRNA tributyltin results in increased expression of ZFP300 mRNA
CTD
PMID:31129395
NCBI chr12:133,037,509...133,063,299
Ensembl chr12:133,037,292...133,063,304
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