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Gene: SLC30A4 (solute carrier family 30 member 4) Homo sapiens
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Symbol: SLC30A4
Name: solute carrier family 30 member 4
Description: Zinc is the second most abundant trace metal in the human body. It is an essential element, serving both a structural role, as in the formation of zinc fingers in DNA-binding proteins, and a catalytic role in metalloenzymes, such as pancreatic carboxypeptidases (e.g., MIM 114852), alkaline phosphatases (e.g., MIM 171760), various dehydrogenases, and superoxide dismutases (e.g., MIM 147450). SLC30A4, or ZNT4, belongs to the ZNT family of zinc transporters. ZNTs are involved in transporting zinc out of the cytoplasm and have similar structures, consisting of 6 transmembrane domains and a histidine-rich cytoplasmic loop (Huang and Gitschier, 1997 [PubMed 9354792]).[supplied by OMIM, Mar 2008]
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: solute carrier family 30 (zinc transporter), member 4; zinc transporter 4; znT-4; ZNT4
Orthologs:
Mus musculus (house mouse) : Slc30a4 (solute carrier family 30 (zinc transporter), member 4)  MGI  Alliance
Rattus norvegicus (Norway rat) : Slc30a4 (solute carrier family 30 member 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Slc30a4 (solute carrier family 30 member 4)
Pan paniscus (bonobo/pygmy chimpanzee) : SLC30A4 (solute carrier family 30 member 4)
Canis lupus familiaris (dog) : SLC30A4 (solute carrier family 30 member 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Slc30a4 (solute carrier family 30 member 4)
Sus scrofa (pig) : SLC30A4 (solute carrier family 30 member 4)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381545,479,613 - 45,523,755 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371545,774,676 - 45,815,005 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361543,561,968 - 43,602,294 (-)NCBINCBI36hg18NCBI36
Build 341543,561,973 - 43,602,294NCBI
Celera1522,665,835 - 22,706,156 (-)NCBI
Cytogenetic Map15q21.1NCBI
HuRef1522,597,857 - 22,638,012 (-)NCBIHuRef
CHM1_11545,890,034 - 45,933,215 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
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References - uncurated
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Genomics

Comparative Map Data
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miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
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Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on SLC30A4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1343503
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-06-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.