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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | COX7A2L | Human | (S)-nicotine | multiple interactions | ISO | Cox7a2l (Mus musculus) | 6480464 | [Nicotine co-treated with 1-Methyl-4-phenyl-1 more ... | CTD | PMID:20230807 | COX7A2L | Human | 1,2-dimethylhydrazine | increases expression | ISO | Cox7a2l (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in increased expression of COX7A2L mRNA | CTD | PMID:22206623 | COX7A2L | Human | 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine | decreases expression | ISO | Cox7a2l (Mus musculus) | 6480464 | 1-Methyl-4-phenyl-1 more ... | CTD | PMID:20230807 | COX7A2L | Human | 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine | multiple interactions | ISO | Cox7a2l (Mus musculus) | 6480464 | [Caffeine co-treated with 1-Methyl-4-phenyl-1 more ... | CTD | PMID:20230807 | COX7A2L | Human | 17alpha-ethynylestradiol | affects expression | ISO | Cox7a2l (Mus musculus) | 6480464 | Ethinyl Estradiol affects the expression of COX7A2L mRNA | CTD | PMID:17555576 | COX7A2L | Human | 17alpha-ethynylestradiol | multiple interactions | ISO | Cox7a2l (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in decreased expression of COX7A2L mRNA | CTD | PMID:17942748 | COX7A2L | Human | 17alpha-ethynylestradiol | increases expression | ISO | Cox7a2l (Mus musculus) | 6480464 | Ethinyl Estradiol results in increased expression of COX7A2L mRNA | CTD | PMID:17942748 | COX7A2L | Human | 17beta-estradiol | increases expression | EXP | | 6480464 | Estradiol results in increased expression of COX7A2L mRNA | CTD | PMID:17266178 | COX7A2L | Human | 2,3',4,4',5-Pentachlorobiphenyl | increases expression | ISO | Cox7a2l (Mus musculus) | 6480464 | 2 more ... | CTD | PMID:31388691 | COX7A2L | Human | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Cox7a2l (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in decreased expression of COX7A2L mRNA | CTD | PMID:17942748 | COX7A2L | Human | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Cox7a2l (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of COX7A2L mRNA | CTD | PMID:33387578 | COX7A2L | Human | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of COX7A2L mRNA | CTD | PMID:23152189 | COX7A2L | Human | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Cox7a2l (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of COX7A2L mRNA | CTD | PMID:21570461 | COX7A2L | Human | 4,4'-sulfonyldiphenol | multiple interactions | ISO | Cox7a2l (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of COX7A2L mRNA | CTD | PMID:36041667 | COX7A2L | Human | 6-propyl-2-thiouracil | decreases expression | ISO | Cox7a2l (Rattus norvegicus) | 6480464 | Propylthiouracil results in decreased expression of COX7A2L mRNA | CTD | PMID:18077114 | COX7A2L | Human | arsenite(3-) | multiple interactions | EXP | | 6480464 | arsenite promotes the reaction [G3BP1 protein binds to COX7A2L mRNA] | CTD | PMID:32406909 | COX7A2L | Human | bisphenol A | increases expression | ISO | Cox7a2l (Rattus norvegicus) | 6480464 | bisphenol A results in increased expression of COX7A2L mRNA | CTD | PMID:25181051 | COX7A2L | Human | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of COX7A2L protein | CTD | PMID:37567409 | COX7A2L | Human | bisphenol A | increases expression | ISO | Cox7a2l (Mus musculus) | 6480464 | bisphenol A results in increased expression of COX7A2L mRNA | CTD | PMID:32156529 | COX7A2L | Human | bisphenol A | decreases expression | ISO | Cox7a2l (Mus musculus) | 6480464 | bisphenol A results in decreased expression of COX7A2L mRNA | CTD | PMID:33221593 | COX7A2L | Human | bisphenol A | decreases expression | ISO | Cox7a2l (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of COX7A2L mRNA | CTD | PMID:34947998 | COX7A2L | Human | bisphenol A | multiple interactions | ISO | Cox7a2l (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of COX7A2L mRNA and [bisphenol A co-treated with tributyltin] results in increased expression of COX7A2L mRNA | CTD | PMID:31129395 and PMID:36041667 | COX7A2L | Human | bisphenol F | increases expression | ISO | Cox7a2l (Mus musculus) | 6480464 | bisphenol F results in increased expression of COX7A2L mRNA | CTD | PMID:38685157 | COX7A2L | Human | bisphenol F | multiple interactions | ISO | Cox7a2l (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of COX7A2L mRNA | CTD | PMID:36041667 | COX7A2L | Human | buspirone | increases expression | ISO | Cox7a2l (Rattus norvegicus) | 6480464 | Buspirone results in increased expression of COX7A2L mRNA | CTD | PMID:24136188 | COX7A2L | Human | cadmium atom | multiple interactions | ISO | Cox7a2l (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of COX7A2L mRNA | CTD | PMID:37325564 | COX7A2L | Human | cadmium dichloride | multiple interactions | ISO | Cox7a2l (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of COX7A2L mRNA | CTD | PMID:37325564 | COX7A2L | Human | caffeine | multiple interactions | ISO | Cox7a2l (Mus musculus) | 6480464 | [Caffeine co-treated with 1-Methyl-4-phenyl-1 more ... | CTD | PMID:20230807 | COX7A2L | Human | carbon nanotube | decreases expression | ISO | Cox7a2l (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | COX7A2L | Human | carbon nanotube | increases expression | ISO | Cox7a2l (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25620056 | COX7A2L | Human | chloropicrin | affects expression | EXP | | 6480464 | chloropicrin affects the expression of COX7A2L mRNA | CTD | PMID:26352163 | COX7A2L | Human | chlorpyrifos | increases expression | ISO | Cox7a2l (Mus musculus) | 6480464 | Chlorpyrifos results in increased expression of COX7A2L mRNA | CTD | PMID:37019170 | COX7A2L | Human | copper(II) sulfate | decreases expression | EXP | | 6480464 | Copper Sulfate results in decreased expression of COX7A2L mRNA | CTD | PMID:19549813 | COX7A2L | Human | crocidolite asbestos | increases expression | EXP | | 6480464 | Asbestos and Crocidolite results in increased expression of COX7A2L mRNA | CTD | PMID:29523930 | COX7A2L | Human | cyclosporin A | increases expression | EXP | | 6480464 | Cyclosporine results in increased expression of COX7A2L mRNA | CTD | PMID:25562108 | COX7A2L | Human | daidzein | increases expression | EXP | | 6480464 | daidzein results in increased expression of COX7A2L mRNA | CTD | PMID:17266178 | COX7A2L | Human | dicrotophos | decreases expression | EXP | | 6480464 | dicrotophos results in decreased expression of COX7A2L mRNA | CTD | PMID:28302478 | COX7A2L | Human | doxorubicin | increases expression | EXP | | 6480464 | Doxorubicin results in increased expression of COX7A2L mRNA | CTD | PMID:29803840 | COX7A2L | Human | flutamide | increases expression | ISO | Cox7a2l (Mus musculus) | 6480464 | Flutamide results in increased expression of COX7A2L mRNA | CTD | PMID:17702527 | COX7A2L | Human | genistein | increases expression | EXP | | 6480464 | Genistein results in increased expression of COX7A2L mRNA | CTD | PMID:17266178 | COX7A2L | Human | genistein | decreases expression | EXP | | 6480464 | Genistein results in decreased expression of COX7A2L protein | CTD | PMID:20884965 | COX7A2L | Human | genistein | multiple interactions | EXP | | 6480464 | ESR2 promotes the reaction [Genistein results in decreased expression of COX7A2L protein] | CTD | PMID:20884965 | COX7A2L | Human | ivermectin | increases expression | EXP | | 6480464 | Ivermectin results in increased expression of COX7A2L protein | CTD | PMID:32959892 | COX7A2L | Human | lipopolysaccharide | decreases expression | EXP | | 6480464 | Lipopolysaccharides results in decreased expression of COX7A2L mRNA | CTD | PMID:31059760 | COX7A2L | Human | lipopolysaccharide | multiple interactions | EXP | | 6480464 | [Acetaminophen co-treated with Lipopolysaccharides] results in decreased expression of COX7A2L mRNA | CTD | PMID:31059760 | COX7A2L | Human | maneb | multiple interactions | ISO | Cox7a2l (Mus musculus) | 6480464 | [Paraquat co-treated with Maneb] results in decreased expression of COX7A2L mRNA | CTD | PMID:18386188 | COX7A2L | Human | monosodium L-glutamate | increases expression | ISO | Cox7a2l (Mus musculus) | 6480464 | Sodium Glutamate results in increased expression of COX7A2L mRNA | CTD | PMID:20111022 | COX7A2L | Human | N,N-diethyl-m-toluamide | multiple interactions | ISO | Cox7a2l (Rattus norvegicus) | 6480464 | [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of COX7A2L mRNA | CTD | PMID:28659758 | COX7A2L | Human | nicotine | multiple interactions | ISO | Cox7a2l (Mus musculus) | 6480464 | [Nicotine co-treated with 1-Methyl-4-phenyl-1 more ... | CTD | PMID:20230807 | COX7A2L | Human | ochratoxin A | increases expression | EXP | | 6480464 | ochratoxin A results in increased expression of COX7A2L mRNA | CTD | PMID:17316727 | COX7A2L | Human | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of COX7A2L mRNA | CTD | PMID:25704631 | COX7A2L | Human | paracetamol | multiple interactions | EXP | | 6480464 | [Acetaminophen co-treated with Lipopolysaccharides] results in decreased expression of COX7A2L mRNA | CTD | PMID:31059760 | COX7A2L | Human | paraquat | multiple interactions | ISO | Cox7a2l (Mus musculus) | 6480464 | [Paraquat co-treated with Maneb] results in decreased expression of COX7A2L mRNA | CTD | PMID:18386188 | COX7A2L | Human | perfluorohexanesulfonic acid | increases expression | EXP | | 6480464 | perfluorohexanesulfonic acid results in increased expression of COX7A2L mRNA | CTD | PMID:25812627 | COX7A2L | Human | perfluorooctane-1-sulfonic acid | increases expression | EXP | | 6480464 | perfluorooctane sulfonic acid results in increased expression of COX7A2L mRNA | CTD | PMID:25812627 | COX7A2L | Human | permethrin | multiple interactions | ISO | Cox7a2l (Rattus norvegicus) | 6480464 | [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of COX7A2L mRNA | CTD | PMID:28659758 | COX7A2L | Human | pirinixic acid | increases expression | ISO | Cox7a2l (Mus musculus) | 6480464 | pirinixic acid results in increased expression of COX7A2L mRNA | CTD | PMID:16221962 | COX7A2L | Human | Pyridostigmine bromide | multiple interactions | ISO | Cox7a2l (Rattus norvegicus) | 6480464 | [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of COX7A2L mRNA | CTD | PMID:28659758 | COX7A2L | Human | rotenone | increases expression | ISO | Cox7a2l (Mus musculus) | 6480464 | Rotenone results in increased expression of COX7A2L mRNA | CTD | PMID:17702527 | COX7A2L | Human | sodium arsenite | increases expression | EXP | | 6480464 | sodium arsenite results in increased expression of COX7A2L mRNA | CTD | PMID:38568856 | COX7A2L | Human | sodium fluoride | decreases expression | ISO | Cox7a2l (Mus musculus) | 6480464 | Sodium Fluoride results in decreased expression of COX7A2L protein | CTD | PMID:28918527 | COX7A2L | Human | tamoxifen | affects expression | ISO | Cox7a2l (Mus musculus) | 6480464 | Tamoxifen affects the expression of COX7A2L mRNA | CTD | PMID:17555576 | COX7A2L | Human | testosterone | decreases expression | EXP | | 6480464 | Testosterone results in decreased expression of COX7A2L mRNA | CTD | PMID:33359661 | COX7A2L | Human | thiram | increases expression | EXP | | 6480464 | Thiram results in increased expression of COX7A2L mRNA | CTD | PMID:38568856 | COX7A2L | Human | titanium dioxide | decreases expression | ISO | Cox7a2l (Mus musculus) | 6480464 | titanium dioxide results in decreased expression of COX7A2L mRNA | CTD | PMID:23557971 | COX7A2L | Human | toluene | affects expression | ISO | Cox7a2l (Rattus norvegicus) | 6480464 | Toluene affects the expression of COX7A2L mRNA | CTD | PMID:21827849 | COX7A2L | Human | tributylstannane | multiple interactions | ISO | Cox7a2l (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with tributyltin] results in increased expression of COX7A2L mRNA | CTD | PMID:31129395 | COX7A2L | Human | valproic acid | increases expression | ISO | Cox7a2l (Mus musculus) | 6480464 | Valproic Acid results in increased expression of COX7A2L mRNA | CTD | PMID:19136453 | COX7A2L | Human | vinclozolin | decreases methylation | ISO | Cox7a2l (Rattus norvegicus) | 6480464 | vinclozolin results in decreased methylation of COX7A2L gene | CTD | PMID:31079544 | COX7A2L | Human | zinc atom | decreases expression | EXP | | 6480464 | Zinc deficiency results in decreased expression of COX7A2L mRNA | CTD | PMID:22171008 | COX7A2L | Human | zinc(0) | decreases expression | EXP | | 6480464 | Zinc deficiency results in decreased expression of COX7A2L mRNA | CTD | PMID:22171008 | |