Gene: TRPV1 (transient receptor potential cation channel subfamily V member 1) Homo sapiens
Symbol: TRPV1
Name: transient receptor potential cation channel subfamily V member 1
Description: Capsaicin, the main pungent ingredient in hot chili peppers, elicits a sensation of burning pain by selectively activating sensory neurons that convey information about noxious stimuli to the central nervous system. The protein encoded by this gene is a receptor for capsaicin and is a non-selective cation channel that is structurally related to members of the TRP family of ion channels. This receptor is also activated by increases in temperature in the noxious range, suggesting that it functions as a transducer of painful thermal stimuli in vivo. Four transcript variants encoding the same protein, but with different 5' UTR sequence, have been described for this gene. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: capsaicin receptor; DKFZp434K0220; osm-9-like TRP channel 1; OTRPC1; transient receptor potential cation channel, subfamily V, member 1; transient receptor potential vanilloid 1a; transient receptor potential vanilloid 1b; vanilloid receptor 1; vanilloid receptor subtype 1; VR1
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38173,565,446 - 3,609,411 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37173,468,740 - 3,512,705 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36173,415,490 - 3,459,454 (-)NCBINCBI36hg18NCBI36
Build 34173,415,490 - 3,442,920NCBI
Celera173,482,474 - 3,526,423 (-)NCBI
Cytogenetic Map17p13.2NCBI
HuRef173,360,449 - 3,404,458 (-)NCBIHuRef
CHM1_1173,479,568 - 3,523,488 (-)NCBICHM1_1
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Nucleotide Sequences
Protein Sequences
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Additional Information

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Nomenclature History
More on TRPV1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
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RGD Object Information
RGD ID: 733197
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2018-03-13
Status: ACTIVE