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Gene: LPCAT3 (lysophosphatidylcholine acyltransferase 3) Homo sapiens
Symbol: LPCAT3
Name: lysophosphatidylcholine acyltransferase 3
RGD ID: 1604396
Description: Exhibits 1-acylglycerophosphocholine O-acyltransferase activity; 1-acylglycerophosphoethanolamine O-acyltransferase activity; and 1-acylglycerophosphoserine O-acyltransferase activity. Involved in phosphatidylcholine acyl-chain remodeling; phosphatidylethanolamine acyl-chain remodeling; and phosphatidylserine acyl-chain remodeling. Localizes to endoplasmic reticulum membrane; PARTICIPATES IN glycerophospholipid metabolic pathway; INTERACTS WITH 17beta-estradiol; 4,4'-sulfonyldiphenol; aflatoxin B1.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1-acylglycerophosphocholine O-acyltransferase; 1-acylglycerophosphoethanolamine O-acyltransferase; 1-acylglycerophosphoserine O-acyltransferase; C3F; LPCAT; LPLAT 5; LPSAT; lyso-PC acyltransferase 3; lyso-PS acyltransferase; lysophosphatidylserine acyltransferase; lysophospholipid acyltransferase 5; MBOAT5; membrane bound O-acyltransferase domain containing 5; membrane-bound O-acyltransferase domain-containing protein 5; nessy; O-acyltransferase (membrane bound) domain containing 5; O-acyltransferase domain-containing protein 5; OACT5; putative protein similar to nessy
Mus musculus (house mouse) : Lpcat3 (lysophosphatidylcholine acyltransferase 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Lpcat3 (lysophosphatidylcholine acyltransferase 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lpcat3 (lysophosphatidylcholine acyltransferase 3)
Pan paniscus (bonobo/pygmy chimpanzee) : LPCAT3 (lysophosphatidylcholine acyltransferase 3)
Canis lupus familiaris (dog) : LPCAT3 (lysophosphatidylcholine acyltransferase 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lpcat3 (lysophosphatidylcholine acyltransferase 3)
Sus scrofa (pig) : LPCAT3 (lysophosphatidylcholine acyltransferase 3)
Chlorocebus sabaeus (African green monkey) : LPCAT3 (lysophosphatidylcholine acyltransferase 3)
Heterocephalus glaber (naked mole-rat) : Lpcat3 (lysophosphatidylcholine acyltransferase 3)
more info ...
Related Pseudogenes: AL136228.1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl126,976,185 - 7,018,477 (-)EnsemblGRCh38hg38GRCh38
GRCh38126,976,185 - 7,018,508 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37127,085,347 - 7,125,842 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36126,955,608 - 6,996,103 (-)NCBINCBI36hg18NCBI36
Celera128,706,367 - 8,748,731 (-)NCBI
Cytogenetic Map12p13.31NCBI
HuRef126,943,813 - 6,986,151 (-)NCBIHuRef
CHM1_1127,084,301 - 7,124,856 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on LPCAT3
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1604396
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2020-09-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.