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Gene: ITGA6 (integrin subunit alpha 6) Homo sapiens
Symbol: ITGA6
Name: integrin subunit alpha 6
Description: Exhibits insulin-like growth factor I binding activity and neuregulin binding activity. Involved in several processes, including positive regulation of cellular metabolic process; regulation of apoptotic process; and skin morphogenesis. Localizes to the cell surface and plasma membrane. Implicated in junctional epidermolysis bullosa and junctional epidermolysis bullosa with pyloric atresia.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CD49 antigen-like family member F; CD49f; DKFZp686J01244; FLJ18737; integrin alpha 6; integrin alpha-6; integrin alpha6B; integrin, alpha 6; ITGA6B; VLA-6
Mus musculus (house mouse) : Itga6 (integrin alpha 6)  MGI  Alliance
Rattus norvegicus (Norway rat) : Itga6 (integrin subunit alpha 6)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Itga6 (integrin subunit alpha 6)
Pan paniscus (bonobo/pygmy chimpanzee) : ITGA6 (integrin subunit alpha 6)
Canis lupus familiaris (dog) : ITGA6 (integrin subunit alpha 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Itga6 (integrin subunit alpha 6)
Sus scrofa (pig) : ITGA6 (integrin subunit alpha 6)
Chlorocebus sabaeus (green monkey) : ITGA6 (integrin subunit alpha 6)
Heterocephalus glaber (naked mole-rat) : Itga6 (integrin subunit alpha 6)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl2172,427,354 - 172,506,459 (+)Ensembl
GRCh382172,427,336 - 172,506,459 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372173,291,954 - 173,371,181 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362173,000,560 - 173,079,427 (+)NCBINCBI36hg18NCBI36
Build 342173,117,876 - 173,196,509NCBI
Celera2166,905,512 - 166,984,375 (+)NCBI
Cytogenetic Map2q31.1NCBI
HuRef2165,170,787 - 165,249,645 (+)NCBIHuRef
CHM1_12173,299,260 - 173,378,363 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on ITGA6
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 731429
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-02-11
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.