TP53INP2 (tumor protein p53 inducible nuclear protein 2) - Rat Genome Database

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Gene: TP53INP2 (tumor protein p53 inducible nuclear protein 2) Homo sapiens
Analyze
Symbol: TP53INP2
Name: tumor protein p53 inducible nuclear protein 2
RGD ID: 1352381
HGNC Page HGNC:16104
Description: Predicted to enable ubiquitin binding activity. Involved in autophagosome assembly and positive regulation of DNA-templated transcription. Located in autophagosome; cytosol; and nucleus.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: C20orf110; diabetes and obesity regulated; diabetes and obesity-regulated; dJ1181N3.1; DKFZp434B2411; DKFZp434O0827; DOR; FLJ21759; FLJ23500; p53-inducible protein U; PIG-U; PIGU; PINH; tumor protein p53-inducible nuclear protein 2
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382034,704,344 - 34,713,436 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2034,704,339 - 34,713,439 (+)EnsemblGRCh38hg38GRCh38
GRCh372033,292,148 - 33,301,240 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362032,755,809 - 32,764,898 (+)NCBINCBI36Build 36hg18NCBI36
Build 342032,755,808 - 32,764,898NCBI
Celera2030,041,236 - 30,050,322 (+)NCBICelera
Cytogenetic Map20q11.22NCBI
HuRef2030,071,142 - 30,080,228 (+)NCBIHuRef
CHM1_12033,193,630 - 33,202,719 (+)NCBICHM1_1
T2T-CHM13v2.02036,425,010 - 36,434,099 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
TP53INP2Humanglutathione synthetase deficiency  IAGPRGD:4058746128554872ClinVar Annotator: match by term: PYROGLUTAMIC ACIDURIAClinVarPMID:12638941|PMID:15717202|PMID:28492532
TP53INP2Humanglutatione synthetase deficiency with 5-oxoprolinuria  IAGPRGD:4058746128554872ClinVar Annotator: match by term: 5-OXOPROLINURIA DUE TO GLUTATHIONE SYNTHETASE DEFICIENCYClinVarPMID:12638941|PMID:15717202|PMID:28492532
TP53INP2Humanlong QT syndrome  IAGPRGD:13819266|RGD:138196798554872ClinVar Annotator: match by term: Long QT syndromeClinVarPMID:28492532

1 to 20 of 147 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
TP53INP2Human(+)-schisandrin B multiple interactionsISORGD:7350856480464schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of TP53INP2 mRNA]CTDPMID:31150632
TP53INP2Human(1->4)-beta-D-glucan multiple interactionsISORGD:16150996480464[perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of TRP53INP2 mRNACTDPMID:36331819
TP53INP2Human1,2-dimethylhydrazine multiple interactionsISORGD:7350856480464[APC protein affects the susceptibility to 1,2-Dimethylhydrazine] which results in increased expression of TP53INP2 mRNACTDPMID:27840820
TP53INP2Human1,2-dimethylhydrazine multiple interactionsISORGD:16150996480464[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of TRP53INP2 mRNACTDPMID:22206623
TP53INP2Human1,2-dimethylhydrazine decreases expressionISORGD:161509964804641,2-Dimethylhydrazine results in decreased expression of TRP53INP2 mRNACTDPMID:22206623
TP53INP2Human17alpha-ethynylestradiol increases expressionISORGD:16150996480464Ethinyl Estradiol results in increased expression of TRP53INP2 mRNACTDPMID:17942748
TP53INP2Human17alpha-ethynylestradiol multiple interactionsISORGD:16150996480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of TRP53INP2 mRNACTDPMID:17942748
TP53INP2Human17beta-estradiol decreases expressionEXP 6480464Estradiol results in decreased expression of TP53INP2 mRNACTDPMID:20106945
TP53INP2Human17beta-estradiol increases expressionISORGD:7350856480464Estradiol results in increased expression of TP53INP2 mRNACTDPMID:32145629|PMID:35192832
TP53INP2Human17beta-estradiol affects expressionEXP 6480464Estradiol affects the expression of TP53INP2 mRNACTDPMID:22574217
TP53INP2Human17beta-estradiol increases expressionISORGD:16150996480464Estradiol results in increased expression of TRP53INP2 mRNACTDPMID:15289156|PMID:39298647
TP53INP2Human2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISORGD:16150996480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of TRP53INP2 mRNACTDPMID:17942748
TP53INP2Human2,3,7,8-tetrachlorodibenzodioxine increases expressionISORGD:7350856480464Tetrachlorodibenzodioxin results in increased expression of TP53INP2 mRNACTDPMID:34747641
TP53INP2Human2,3,7,8-tetrachlorodibenzodioxine decreases expressionISORGD:16150996480464Tetrachlorodibenzodioxin results in decreased expression of TRP53INP2 mRNACTDPMID:26290441|PMID:28922406
TP53INP2Human2,3,7,8-tetrachlorodibenzodioxine affects expressionISORGD:16150996480464Tetrachlorodibenzodioxin affects the expression of TRP53INP2 mRNACTDPMID:21570461
TP53INP2Human2,3,7,8-tetrachlorodibenzodioxine affects expressionISORGD:7350856480464Tetrachlorodibenzodioxin affects the expression of TRP53INP2 mRNACTDPMID:22298810
TP53INP2Human2,3,7,8-tetrachlorodibenzodioxine affects expressionEXP 6480464Tetrachlorodibenzodioxin affects the expression of TP53INP2 mRNACTDPMID:22298810
TP53INP2Human2,6-dinitrotoluene affects expressionISORGD:73508564804642,6-dinitrotoluene affects the expression of TRP53INP2 mRNACTDPMID:21346803
TP53INP2Human2-palmitoylglycerol increases expressionEXP 64804642-palmitoylglycerol results in increased expression of TP53INP2 mRNACTDPMID:37199045
TP53INP2Human3-methylcholanthrene decreases expressionISORGD:16150996480464Methylcholanthrene results in decreased expression of TRP53INP2 mRNACTDPMID:20713471

1 to 20 of 147 rows

Biological Process
1 to 11 of 11 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
TP53INP2Humanautophagosome assembly involved_inIDA 150520179 PMID:19056683GO_CentralPMID:19056683
TP53INP2Humanautophagosome assembly involved_inIBAPANTHER:PTN001270888|UniProtKB:Q8IXH6150520179 GO_CentralGO_REF:0000033
TP53INP2Humanautophagy involved_inIEAUniProtKB-KW:KW-0072150520179 UniProtGO_REF:0000043
TP53INP2Humanmacroautophagy acts_upstream_of_or_withinIEAUniProtKB:Q8CFU8|ensembl:ENSMUSP00000037627150520179 EnsemblGO_REF:0000107
TP53INP2Humannegative regulation of protein localization acts_upstream_of_or_withinIEAUniProtKB:Q8CFU8|ensembl:ENSMUSP00000037627150520179 EnsemblGO_REF:0000107
TP53INP2Humanosteoblast differentiation acts_upstream_of_or_withinIEAUniProtKB:Q8CFU8|ensembl:ENSMUSP00000037627150520179 EnsemblGO_REF:0000107
TP53INP2Humanpositive regulation of DNA-templated transcription involved_inIDA 150520179 PMID:22470510UniProtPMID:22470510
TP53INP2Humanpositive regulation of DNA-templated transcription involved_inIBAFB:FBgn0035542|PANTHER:PTN001270888|UniProtKB:Q8IXH6|UniProtKB:Q96A56150520179 GO_CentralGO_REF:0000033
TP53INP2Humanprotein localization acts_upstream_ofIEAUniProtKB:Q8CFU8|ensembl:ENSMUSP00000037627150520179 EnsemblGO_REF:0000107
TP53INP2Humantissue homeostasis acts_upstream_of_or_withinIEAUniProtKB:Q8CFU8|ensembl:ENSMUSP00000037627150520179 EnsemblGO_REF:0000107
TP53INP2Humanubiquitin-dependent protein catabolic process acts_upstream_of_or_withinIEAUniProtKB:Q8CFU8|ensembl:ENSMUSP00000037627150520179 EnsemblGO_REF:0000107
1 to 11 of 11 rows

Cellular Component
1 to 12 of 12 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
TP53INP2Humanautophagosome located_inIDA 150520179 PMID:19056683, PMID:22470510UniProtPMID:19056683|PMID:22470510
TP53INP2Humanautophagosome is_active_inIBAPANTHER:PTN001270888|UniProtKB:Q8IXH6|UniProtKB:Q96A56150520179 GO_CentralGO_REF:0000033
TP53INP2Humanautophagosome located_inIEAUniProtKB-SubCell:SL-0023150520179 UniProtGO_REF:0000044
TP53INP2Humancytoplasm located_inIEAUniProtKB-KW:KW-0963150520179 UniProtGO_REF:0000043
TP53INP2Humancytoplasmic vesicle located_inIEAUniProtKB-KW:KW-0968150520179 UniProtGO_REF:0000043
TP53INP2Humancytosol located_inIDA 150520179 PMID:22470510UniProtPMID:22470510
TP53INP2Humancytosol located_inIEAUniProtKB-SubCell:SL-0091150520179 UniProtGO_REF:0000044
TP53INP2Humannucleus is_active_inIBAMGI:1926609|PANTHER:PTN001270888|UniProtKB:Q8IXH6|UniProtKB:Q96A56150520179 GO_CentralGO_REF:0000033
TP53INP2Humannucleus located_inIEAUniProtKB-SubCell:SL-0191150520179 UniProtGO_REF:0000044
TP53INP2Humannucleus located_inIDA 150520179 PMID:19056683, PMID:22470510, PMID:23728790ParkinsonsUK-UCLPMID:19056683|PMID:22470510|PMID:23728790
TP53INP2Humannucleus located_inIEAUniProtKB-KW:KW-0539150520179 UniProtGO_REF:0000043
TP53INP2HumanPML body located_inIEAUniProtKB-SubCell:SL-0465150520179 UniProtGO_REF:0000044
1 to 12 of 12 rows

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
TP53INP2Humanprotein binding enablesIPIUniProtKB:O95166|UniProtKB:P60520|UniProtKB:Q96GC9|UniProtKB:Q9H492150520179 PMID:19056683UniProtPMID:19056683
TP53INP2Humanprotein binding enablesIPIUniProtKB:O95166|UniProtKB:P60520|UniProtKB:Q9BXW4|UniProtKB:Q9GZQ8|UniProtKB:Q9H0R8|UniProtKB:Q9H492150520179 PMID:22470510UniProtPMID:22470510
TP53INP2Humanubiquitin binding enablesIEAUniProtKB:Q8CFU8|ensembl:ENSMUSP00000037627150520179 EnsemblGO_REF:0000107

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
TP53INP2HumanProlonged QT interval  IAGPRGD:1267619038554872ClinVar Annotator: match by term: Long QT syndromeClinVar 
TP53INP2HumanProlonged QT interval  IAGPRGD:138196798554872ClinVar Annotator: match by term: Long QT syndromeClinVarPMID:28492532
TP53INP2HumanProlonged QT interval  IAGPRGD:138192668554872ClinVar Annotator: match by term: Long QT syndromeClinVarPMID:28492532
TP53INP2HumanReduced glutathione synthetase level  IAGPRGD:4058746128554872ClinVar Annotator: match by term: Reduced glutathione synthetase levelClinVarPMID:12638941|PMID:15717202|PMID:28492532

#
Reference Title
Reference Citation
1. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
PMID:11780052   PMID:15489334   PMID:15628030   PMID:17238154   PMID:19056683   PMID:19934309   PMID:20010805   PMID:21467300   PMID:21873635   PMID:22470510   PMID:22750142   PMID:23728790  
PMID:23954414   PMID:24713655   PMID:25104271   PMID:25601754   PMID:26213321   PMID:27172002   PMID:28131096   PMID:28957356   PMID:29593329   PMID:30767704   PMID:30853298   PMID:30979779  
PMID:31155706   PMID:31931658   PMID:32535070   PMID:35044719   PMID:35271311   PMID:35615533   PMID:35954230   PMID:36650573   PMID:36675134   PMID:37704626   PMID:37995453   PMID:38545813  



TP53INP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382034,704,344 - 34,713,436 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2034,704,339 - 34,713,439 (+)EnsemblGRCh38hg38GRCh38
GRCh372033,292,148 - 33,301,240 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362032,755,809 - 32,764,898 (+)NCBINCBI36Build 36hg18NCBI36
Build 342032,755,808 - 32,764,898NCBI
Celera2030,041,236 - 30,050,322 (+)NCBICelera
Cytogenetic Map20q11.22NCBI
HuRef2030,071,142 - 30,080,228 (+)NCBIHuRef
CHM1_12033,193,630 - 33,202,719 (+)NCBICHM1_1
T2T-CHM13v2.02036,425,010 - 36,434,099 (+)NCBIT2T-CHM13v2.0
Trp53inp2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392155,223,742 - 155,231,767 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2155,222,979 - 155,231,770 (+)EnsemblGRCm39 Ensembl
GRCm382155,381,811 - 155,389,847 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2155,381,059 - 155,389,850 (+)EnsemblGRCm38mm10GRCm38
MGSCv372155,207,592 - 155,215,583 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362155,073,297 - 155,081,288 (+)NCBIMGSCv36mm8
Celera2161,314,382 - 161,322,371 (+)NCBICelera
Cytogenetic Map2H1NCBI
cM Map277.26NCBI
Tp53inp2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83164,341,618 - 164,350,270 (+)NCBIGRCr8
mRatBN7.23143,881,427 - 143,890,104 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3143,882,021 - 143,890,097 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3147,748,945 - 147,756,921 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03156,366,216 - 156,374,192 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03154,105,748 - 154,113,724 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03150,910,398 - 150,918,525 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3150,910,398 - 150,918,525 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03157,278,515 - 157,286,642 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43145,878,005 - 145,886,088 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13145,783,626 - 145,788,521 (+)NCBI
Celera3142,607,828 - 142,615,961 (+)NCBICelera
Cytogenetic Map3q41NCBI
Tp53inp2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542226,640,239 - 26,649,291 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542226,640,239 - 26,649,291 (-)NCBIChiLan1.0ChiLan1.0
TP53INP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22140,438,314 - 40,447,459 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12040,431,438 - 40,440,564 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02031,033,855 - 31,042,976 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12032,160,155 - 32,169,227 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2032,160,155 - 32,169,227 (+)Ensemblpanpan1.1panPan2
TP53INP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12423,768,208 - 23,801,268 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2423,792,687 - 23,799,331 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2423,413,778 - 23,446,850 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02424,458,763 - 24,492,030 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2424,487,400 - 24,488,930 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12423,746,851 - 23,779,874 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02423,841,988 - 23,875,011 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02424,280,850 - 24,313,887 (+)NCBIUU_Cfam_GSD_1.0
Tp53inp2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640172,756,985 - 172,765,507 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365615,984,079 - 5,992,536 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365615,984,044 - 5,992,536 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TP53INP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1738,104,200 - 38,113,166 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11738,104,189 - 38,113,167 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21743,299,873 - 43,308,842 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TP53INP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1239,002,619 - 39,011,751 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl239,007,023 - 39,008,613 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605087,821,995 - 87,831,175 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tp53inp2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248424,666,640 - 4,675,556 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248424,666,638 - 4,675,576 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in TP53INP2
26 total Variants

1 to 10 of 50 rows
Name
Type
Condition(s)
Position(s)
Clinical significance
GRCh38/hg38 20q11.22-12(chr20:34541747-39663219)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052766]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052766]|See cases [RCV000052766] Chr20:34541747..39663219 [GRCh38]
Chr20:33129551..38291861 [GRCh37]
Chr20:32593212..37725275 [NCBI36]
Chr20:20q11.22-12
pathogenic
GRCh38/hg38 20q11.22-13.11(chr20:34249453-43359749)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053002]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053002]|See cases [RCV000053002] Chr20:34249453..43359749 [GRCh38]
Chr20:32837259..41988389 [GRCh37]
Chr20:32300920..41421803 [NCBI36]
Chr20:20q11.22-13.11
pathogenic
GRCh38/hg38 20p12.2-q12(chr20:9811433-39316956)x3 copy number gain See cases [RCV000052999] Chr20:9811433..39316956 [GRCh38]
Chr20:9792081..37945599 [GRCh37]
Chr20:9740081..37379013 [NCBI36]
Chr20:20p12.2-q12
pathogenic
GRCh38/hg38 20p13-q13.33(chr20:99557-64277321)x3 copy number gain See cases [RCV000135859] Chr20:99557..64277321 [GRCh38]
Chr20:80198..62908674 [GRCh37]
Chr20:28198..62379118 [NCBI36]
Chr20:20p13-q13.33
pathogenic
GRCh38/hg38 20q11.21-11.23(chr20:33432363-36821881)x1 copy number loss See cases [RCV000135440] Chr20:33432363..36821881 [GRCh38]
Chr20:32020169..35450284 [GRCh37]
Chr20:31483830..34883698 [NCBI36]
Chr20:20q11.21-11.23
pathogenic
GRCh38/hg38 20q11.21-11.23(chr20:32062768-35906606)x3 copy number gain See cases [RCV000141833] Chr20:32062768..35906606 [GRCh38]
Chr20:30650571..34494528 [GRCh37]
Chr20:30114232..33957942 [NCBI36]
Chr20:20q11.21-11.23
pathogenic
GRCh37/hg19 20p13-q13.33(chr20:61569-62915555)x3 copy number gain See cases [RCV000510832] Chr20:61569..62915555 [GRCh37]
Chr20:20p13-q13.33
pathogenic
NM_021202.3(TP53INP2):c.440C>T (p.Pro147Leu) single nucleotide variant not specified [RCV004311951] Chr20:34710084 [GRCh38]
Chr20:33297888 [GRCh37]
Chr20:20q11.22
uncertain significance
NM_021202.3(TP53INP2):c.427G>A (p.Ala143Thr) single nucleotide variant not specified [RCV004305551] Chr20:34710071 [GRCh38]
Chr20:33297875 [GRCh37]
Chr20:20q11.22
uncertain significance
GRCh37/hg19 20p13-q13.33(chr20:61569-62915555) copy number gain See cases [RCV000512450] Chr20:61569..62915555 [GRCh37]
Chr20:20p13-q13.33
pathogenic
1 to 10 of 50 rows

Predicted Target Of
Summary Value
Count of predictions:4586
Count of miRNA genes:1105
Interacting mature miRNAs:1409
Transcripts:ENST00000374809, ENST00000374810, ENST00000414082, ENST00000451665
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
597600838GWAS1657698_Hbody mass index QTL GWAS1657698 (human)2e-11body mass indexbody mass index (BMI) (CMO:0000105)203470508934705090Human
597189649GWAS1285723_Htestosterone measurement QTL GWAS1285723 (human)2e-09testosterone measurementserum testosterone level (CMO:0000568)203470918434709185Human
597601137GWAS1657997_Hbody mass index QTL GWAS1657997 (human)1e-11body mass indexbody mass index (BMI) (CMO:0000105)203470508934705090Human

RH28655  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh372033,301,002 - 33,301,086UniSTSGRCh37
Build 362032,764,663 - 32,764,747RGDNCBI36
Celera2030,050,087 - 30,050,171RGD
Cytogenetic Map20q11.22UniSTS
HuRef2030,079,993 - 30,080,077UniSTS
D20S714E  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh372033,301,113 - 33,301,185UniSTSGRCh37
Build 362032,764,774 - 32,764,846RGDNCBI36
Celera2030,050,198 - 30,050,270RGD
Cytogenetic Map20q11.22UniSTS
HuRef2030,080,104 - 30,080,176UniSTS
WI-8949  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh372033,301,005 - 33,301,119UniSTSGRCh37
Build 362032,764,666 - 32,764,780RGDNCBI36
Celera2030,050,090 - 30,050,204RGD
Cytogenetic Map20q11.22UniSTS
HuRef2030,079,996 - 30,080,110UniSTS
GeneMap99-GB4 RH Map20197.2UniSTS
GeneMap99-GB4 RH Map20203.62UniSTS
Whitehead-RH Map20211.5UniSTS
NCBI RH Map20299.3UniSTS
G20521  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh372033,300,953 - 33,301,168UniSTSGRCh37
Build 362032,764,614 - 32,764,829RGDNCBI36
Celera2030,050,038 - 30,050,253RGD
Cytogenetic Map20q11.22UniSTS
HuRef2030,079,944 - 30,080,159UniSTS
A005U42  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh372033,300,953 - 33,301,168UniSTSGRCh37
Build 362032,764,614 - 32,764,829RGDNCBI36
Celera2030,050,038 - 30,050,253RGD
Cytogenetic Map20q11.22UniSTS
HuRef2030,079,944 - 30,080,159UniSTS
GeneMap99-GB4 RH Map20200.16UniSTS




adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
pharyngeal arch
renal system
reproductive system
respiratory system
sensory system
visual system
1204 2439 2788 2253 4974 1726 2351 6 624 1950 465 2270 7305 6471 53 3734 1 852 1744 1617 174 1


1 to 21 of 21 rows
RefSeq Transcripts NM_001329429 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001329430 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001329431 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_021202 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006723841 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AJ297792 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK025412 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK027153 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK292443 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL109824 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL122050 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL137597 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY422170 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC035639 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CA310159 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471077 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068258 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DB479841 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HY108580 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HY150218 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HY157843 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
1 to 21 of 21 rows

Ensembl Acc Id: ENST00000374809   ⟹   ENSP00000363942
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2034,704,339 - 34,713,439 (+)Ensembl
Ensembl Acc Id: ENST00000374810   ⟹   ENSP00000363943
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2034,704,344 - 34,713,436 (+)Ensembl
Ensembl Acc Id: ENST00000414082   ⟹   ENSP00000404410
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2034,704,735 - 34,709,343 (+)Ensembl
Ensembl Acc Id: ENST00000451665   ⟹   ENSP00000395784
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2034,704,350 - 34,709,496 (+)Ensembl
RefSeq Acc Id: NM_001329429   ⟹   NP_001316358
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382034,704,344 - 34,713,436 (+)NCBI
T2T-CHM13v2.02036,425,010 - 36,434,099 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001329430   ⟹   NP_001316359
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382034,704,344 - 34,713,436 (+)NCBI
T2T-CHM13v2.02036,425,010 - 36,434,099 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001329431   ⟹   NP_001316360
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382034,704,719 - 34,713,436 (+)NCBI
T2T-CHM13v2.02036,425,385 - 36,434,099 (+)NCBI
Sequence:
RefSeq Acc Id: NM_021202   ⟹   NP_067025
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382034,704,344 - 34,713,436 (+)NCBI
GRCh372033,292,147 - 33,301,240 (+)NCBI
Build 362032,755,809 - 32,764,898 (+)NCBI Archive
Celera2030,041,236 - 30,050,322 (+)RGD
HuRef2030,071,142 - 30,080,228 (+)ENTREZGENE
CHM1_12033,193,630 - 33,202,719 (+)NCBI
T2T-CHM13v2.02036,425,010 - 36,434,099 (+)NCBI
Sequence:
RefSeq Acc Id: NP_067025   ⟸   NM_021202
- UniProtKB: Q8IYL5 (UniProtKB/Swiss-Prot),   Q5JX64 (UniProtKB/Swiss-Prot),   E1P5P6 (UniProtKB/Swiss-Prot),   A8K8S8 (UniProtKB/Swiss-Prot),   Q9NU00 (UniProtKB/Swiss-Prot),   Q8IXH6 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001316358   ⟸   NM_001329429
- UniProtKB: Q8IYL5 (UniProtKB/Swiss-Prot),   Q5JX64 (UniProtKB/Swiss-Prot),   E1P5P6 (UniProtKB/Swiss-Prot),   A8K8S8 (UniProtKB/Swiss-Prot),   Q9NU00 (UniProtKB/Swiss-Prot),   Q8IXH6 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001316359   ⟸   NM_001329430
- UniProtKB: Q8IYL5 (UniProtKB/Swiss-Prot),   Q5JX64 (UniProtKB/Swiss-Prot),   E1P5P6 (UniProtKB/Swiss-Prot),   A8K8S8 (UniProtKB/Swiss-Prot),   Q9NU00 (UniProtKB/Swiss-Prot),   Q8IXH6 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001316360   ⟸   NM_001329431
- UniProtKB: Q8IYL5 (UniProtKB/Swiss-Prot),   Q5JX64 (UniProtKB/Swiss-Prot),   E1P5P6 (UniProtKB/Swiss-Prot),   A8K8S8 (UniProtKB/Swiss-Prot),   Q9NU00 (UniProtKB/Swiss-Prot),   Q8IXH6 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSP00000395784   ⟸   ENST00000451665

Name Modeler Protein Id AA Range Protein Structure
AF-Q8IXH6-F1-model_v2 AlphaFold Q8IXH6 1-220 view protein structure

RGD ID:6799141
Promoter ID:HG_KWN:39144
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   HeLa_S3,   K562,   Lymphoblastoid,   NB4
Transcripts:ENST00000374809,   OTTHUMT00000078807,   OTTHUMT00000078808,   OTTHUMT00000078810
Position:
Human AssemblyChrPosition (strand)Source
Build 362032,755,641 - 32,756,232 (+)MPROMDB
RGD ID:6812097
Promoter ID:HG_ACW:49017
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   HeLa_S3,   Lymphoblastoid,   NB4
Transcripts:TP53INP2.BAPR07
Position:
Human AssemblyChrPosition (strand)Source
Build 362032,760,746 - 32,761,642 (+)MPROMDB
RGD ID:13206739
Promoter ID:EPDNEW_H26950
Type:initiation region
Name:TP53INP2_1
Description:tumor protein p53 inducible nuclear protein 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh382034,704,344 - 34,704,404EPDNEW


1 to 31 of 31 rows
Database
Acc Id
Source(s)
COSMIC TP53INP2 COSMIC
Ensembl Genes ENSG00000078804 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000374809 ENTREZGENE
  ENST00000374809.6 UniProtKB/Swiss-Prot
  ENST00000374810 ENTREZGENE
  ENST00000374810.8 UniProtKB/Swiss-Prot
GTEx ENSG00000078804 GTEx
HGNC ID HGNC:16104 ENTREZGENE
Human Proteome Map TP53INP2 Human Proteome Map
InterPro TP53INP UniProtKB/Swiss-Prot
KEGG Report hsa:58476 UniProtKB/Swiss-Prot
NCBI Gene 58476 ENTREZGENE
OMIM 617549 OMIM
PANTHER PTHR31671 UniProtKB/Swiss-Prot
  PTHR31671:SF2 UniProtKB/Swiss-Prot
Pfam DOR UniProtKB/Swiss-Prot
PharmGKB PA25650 PharmGKB
UniProt A8K8S8 ENTREZGENE
  E1P5P6 ENTREZGENE
  Q5JX64 ENTREZGENE
  Q5JX65_HUMAN UniProtKB/TrEMBL
  Q5JX66_HUMAN UniProtKB/TrEMBL
  Q8IXH6 ENTREZGENE
  Q8IYL5 ENTREZGENE
  Q9NU00 ENTREZGENE
  T53I2_HUMAN UniProtKB/Swiss-Prot
UniProt Secondary A8K8S8 UniProtKB/Swiss-Prot
  E1P5P6 UniProtKB/Swiss-Prot
  Q5JX64 UniProtKB/Swiss-Prot
  Q8IYL5 UniProtKB/Swiss-Prot
  Q9NU00 UniProtKB/Swiss-Prot
1 to 31 of 31 rows