NFKB1 (nuclear factor kappa B subunit 1) - Rat Genome Database

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Gene: NFKB1 (nuclear factor kappa B subunit 1) Homo sapiens
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Symbol: NFKB1
Name: nuclear factor kappa B subunit 1
RGD ID: 730892
HGNC Page HGNC:7794
Description: Enables several functions, including DNA-binding transcription factor activity, RNA polymerase II-specific; actinin binding activity; and protein sequestering activity. Involved in several processes, including cellular response to cytokine stimulus; intracellular signaling cassette; and regulation of primary metabolic process. Acts upstream of or within cellular response to lipopolysaccharide. Located in cytosol; mitochondrion; and nucleoplasm. Is active in chromatin. Implicated in several diseases, including carcinoma (multiple); common variable immunodeficiency 12; melanoma; prostate cancer; and tropical spastic paraparesis. Biomarker of lung cancer; lung non-small cell carcinoma; pancreatic adenocarcinoma; and stomach cancer.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: CVID12; DKFZp686C01211; DNA binding factor KBF1; DNA-binding factor KBF1; EBP-1; KBF1; MGC54151; NF-kappa-B; NF-kappa-B1; NF-kappaB; NF-kappabeta; NF-kB; NF-kB1; NFkappaB; NFKB-p105; NFKB-p50; nuclear factor kappa-B DNA binding subunit; nuclear factor NF-kappa-B p105 subunit; nuclear factor NF-kappa-B p50 subunit; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1; p105; p50
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
NCBI Annotation Information: Note: This gene has been reviewed for its involvement in coronavirus biology, and is involved in immune response or antiviral activity.
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384102,501,359 - 102,617,302 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl4102,501,330 - 102,617,302 (+)EnsemblGRCh38hg38GRCh38
GRCh374103,422,516 - 103,538,459 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 364103,641,518 - 103,757,507 (+)NCBINCBI36Build 36hg18NCBI36
Build 344103,779,672 - 103,895,661NCBI
Celera4100,721,743 - 100,837,727 (+)NCBICelera
Cytogenetic Map4q24NCBI
HuRef499,158,873 - 99,274,686 (+)NCBIHuRef
CHM1_14103,398,776 - 103,514,779 (+)NCBICHM1_1
T2T-CHM13v2.04105,815,285 - 105,931,246 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model