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Gene: PPP2R5A (protein phosphatase 2 regulatory subunit B'alpha) Homo sapiens
Symbol: PPP2R5A
Name: protein phosphatase 2 regulatory subunit B'alpha
Description: Exhibits kinase binding activity and phosphoprotein phosphatase activity. Involved in negative regulation of protein localization to plasma membrane; protein dephosphorylation; and regulation of phosphate metabolic process. Localizes to several cellular components, including the Z disc; centrosome; and protein phosphatase type 2A complex.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: B56A; B56alpha; MGC131915; PP2A B subunit isoform B'-alpha; PP2A B subunit isoform B56-alpha; PP2A B subunit isoform PR61-alpha; PP2A B subunit isoform R5-alpha; PP2A, B subunit, B' alpha isoform; PP2A, B subunit, B56 alpha isoform; PP2A, B subunit, PR61 alpha isoform; PP2A, B subunit, R5 alpha isoform; PR61A; PR61alpha; protein phosphatase 2, regulatory subunit B (B56), alpha isoform; protein phosphatase 2, regulatory subunit B', alpha isoform; serine/threonine protein phosphatase 2A, 56 kDa regulatory subunit, alpha isoform; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381212,285,410 - 212,361,853 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371212,458,879 - 212,535,205 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361210,525,502 - 210,601,828 (+)NCBINCBI36hg18NCBI36
Build 341208,847,273 - 208,923,599NCBI
Celera1185,685,982 - 185,760,829 (+)NCBI
Cytogenetic Map1q32.3NCBI
HuRef1183,135,716 - 183,210,570 (+)NCBIHuRef
CHM1_11213,731,558 - 213,808,070 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on PPP2R5A
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1317550
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-11-05
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.