ABCB1 (ATP binding cassette subfamily B member 1) - Rat Genome Database

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Gene: ABCB1 (ATP binding cassette subfamily B member 1) Homo sapiens
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Symbol: ABCB1
Name: ATP binding cassette subfamily B member 1
RGD ID: 730823
HGNC Page HGNC:40
Description: Enables several functions, including ATP binding activity; ATPase-coupled intramembrane lipid transporter activity; and ubiquitin protein ligase binding activity. Involved in several processes, including G2/M transition of mitotic cell cycle; lipid translocation; and xenobiotic detoxification by transmembrane export across the plasma membrane. Located in apical plasma membrane; cell surface; and cytoplasm. Implicated in several diseases, including carcinoma (multiple); drug dependence (multiple); human immunodeficiency virus infectious disease (multiple); inflammatory bowel disease (multiple); and leukemia (multiple). Biomarker of several diseases, including familial temporal lobe epilepsy 3; human immunodeficiency virus infectious disease; kidney cancer (multiple); nasal type extranodal NK/T-cell lymphoma; and ovarian cancer.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: ABC20; ATP-binding cassette sub-family B member 1; ATP-binding cassette, sub-family B (MDR/TAP), member 1; ATP-binding cassette, subfamily B, member 1; ATP-dependent translocase ABCB1; CD243; CLCS; colchicin sensitivity; doxorubicin resistance; ENPAT; GP170; MDR1; MGC163296; multidrug resistance protein 1; P glycoprotein; p-170; P-glycoprotein 1; P-GP; PGY1; phospholipid transporter ABCB1
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38787,503,017 - 87,713,295 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl787,503,017 - 87,713,323 (-)EnsemblGRCh38hg38GRCh38
GRCh37787,132,333 - 87,342,611 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36786,970,884 - 87,180,500 (-)NCBINCBI36Build 36hg18NCBI36
Build 34786,777,598 - 86,987,215NCBI
Celera781,837,832 - 82,047,176 (-)NCBICelera
Cytogenetic Map7q21.12NCBI
HuRef781,744,182 - 81,952,578 (-)NCBIHuRef
CHM1_1787,063,281 - 87,272,756 (-)NCBICHM1_1
T2T-CHM13v2.0788,752,787 - 88,963,178 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2786,464,691 - 86,673,953 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
acquired immunodeficiency syndrome  (IAGP)
acute lymphoblastic leukemia  (EXP,IAGP)
adrenocortical carcinoma  (EXP)
allergic rhinitis  (IAGP)
Alzheimer's disease  (ISO)
Anthracycline-induced Cardiotoxicity  (IAGP)
antisocial personality disorder  (IAGP)
asthma  (IEP)
Audiogenic Epilepsy  (ISO)
autism spectrum disorder  (EXP)
Behcet's disease  (IAGP)
Breast Neoplasms  (EXP,IAGP)
cannabis abuse  (EXP)
cannabis dependence  (IAGP)
carcinoma  (EXP)
cardiomyopathy  (ISO)
Chemical and Drug Induced Liver Injury  (EXP,IAGP,ISO)
Chronic Hepatitis C  (IAGP)
chronic myeloid leukemia  (IAGP)
colorectal adenocarcinoma  (IAGP)
Colorectal Neoplasms  (EXP)
congenital heart disease  (EXP)
COVID-19  (HEP)
Critical Illness  (IAGP)
Crohn's disease  (IAGP)
cryoglobulinemia  (IAGP)
diarrhea  (ISO)
diffuse large B-cell lymphoma  (EXP)
disease of cellular proliferation  (EXP)
disease of mental health  (EXP)
Disease Progression  (EXP)
drug dependence  (IAGP)
Drug Overdose  (IAGP)
Drug-induced Neutropenia  (IAGP)
Drug-Related Side Effects and Adverse Reactions  (EXP,ISO)
encephalitis  (ISO)
ENCEPHALOPATHY, ACUTE TRANSIENT  (IAGP)
end stage renal disease  (ISO)
Endotoxemia  (ISO)
Eosinophilia  (IEP)
epilepsy  (EXP,IAGP,ISO)
Escherichia Coli Infections  (EXP)
Esophageal Neoplasms  (EXP)
Experimental Arthritis  (EXP,ISO)
Experimental Diabetes Mellitus  (ISO)
Experimental Liver Cirrhosis  (EXP,ISO)
Experimental Mammary Neoplasms  (ISO)
familial adenomatous polyposis  (ISO)
familial hyperlipidemia  (IAGP,ISO)
familial Mediterranean fever  (IAGP)
familial temporal lobe epilepsy 3  (IAGP,IEP)
Femur Head Necrosis  (IAGP)
Fetal Growth Retardation  (ISO)
Genetic Predisposition to Disease  (EXP)
Genetic Translocation  (EXP)
Germ Cell and Embryonal Neoplasms  (IEP)
head and neck squamous cell carcinoma  (EXP)
heart disease  (ISO)
Helicobacter Infections  (IAGP)
Hematologic Neoplasms  (EXP)
hepatocellular carcinoma  (EXP,IAGP,ISO)
hereditary breast ovarian cancer syndrome  (IAGP)
heroin dependence  (IAGP)
human immunodeficiency virus infectious disease  (IAGP,IEP,ISO)
Idiopathic Generalized Epilepsy  (IAGP)
Inflammation  (ISO)
inflammatory bowel disease 13  (EXP,IAGP,ISS)
invasive ductal carcinoma  (IDA)
kidney disease  (ISO)
Kidney Neoplasms  (EXP)
Latent Tuberculosis  (HEP)
lung non-small cell carcinoma  (EXP,IAGP)
malaria  (IAGP,IDA)
metabolic dysfunction-associated steatotic liver disease  (ISO)
Nasal Polyps  (IEP)
nasal type extranodal NK/T-cell lymphoma  (IEP)
Nausea  (EXP)
Neoplasm Metastasis  (EXP)
nephroblastoma  (IEP)
nervous system disease  (EXP)
neuroblastoma  (EXP)
neutropenia  (EXP)
obstructive sleep apnea  (ISO)
opiate dependence  (IAGP)
Orthostatic Hypotension  (EXP)
ovarian cancer  (IEP)
Pain  (ISO)
Parkinson's disease  (EXP)
perinatal necrotizing enterocolitis  (ISO)
peripheral nervous system disease  (EXP)
pleomorphic xanthoastrocytoma  (IAGP)
Poisoning  (EXP)
Postoperative Pain  (EXP)
pulmonary tuberculosis  (IAGP)
renal cell carcinoma  (IAGP,IEP)
Reperfusion Injury  (ISO)
rheumatoid arthritis  (EXP)
secondary Parkinson disease  (EXP)
ST Elevation Myocardial Infarction  (IAGP)
status epilepticus  (ISO)
temporal lobe epilepsy  (ISO)
toxic encephalopathy  (EXP,IAGP)
type 2 diabetes mellitus  (IAGP)
ulcerative colitis  (IAGP)
Vomiting  (EXP)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-(S)-ar-turmerone  (EXP)
(+)-artemisinin  (EXP)
(+)-isoborneol  (ISO)
(+)-pilocarpine  (ISO)
(+)-schisandrin B  (ISO)
(+)-sesamin  (EXP)
(+)-taxifolin  (EXP)
(+)-Tetrandrine  (EXP,ISO)
(-)-antofine  (EXP)
(-)-demecolcine  (EXP)
(-)-epigallocatechin 3-gallate  (EXP)
(-)-gambogic acid  (EXP)
(-)-matairesinol  (EXP)
(1->4)-beta-D-glucan  (ISO)
(25R)-cholest-5-ene-3beta,26-diol  (EXP)
(9R)-9-[(dimethylamino)methyl]-6,7,10,11-tetrahydro-9H,18H-5,21:12,17-dimethenodibenzo[e,k]pyrrolo[3,4-h][1,4,13]oxadiazacyclohexadecine-18,20-dione  (ISO)
(E,E)-germacrone  (EXP)
(E,E)-hydramethylnon  (EXP)
(R)-lipoic acid  (ISO)
(R,R,R)-alpha-tocopherol  (ISO)
(S)-colchicine  (EXP)
(S)-glaucine  (EXP)
(S)-naringenin  (EXP)
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (EXP)
1,2-dimethylhydrazine  (ISO)
1,3-dinitrobenzene  (ISO)
1,9-dideoxyforskolin  (ISO)
1-\{2-[(4-chlorobenzyl)sulfanyl]-2-(2,4-dichlorophenyl)ethyl\}-1H-imidazole  (EXP)
1-naphthyl isothiocyanate  (ISO)
16alpha,17beta-Estriol 17-(beta-D-glucuronide)  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 17-glucosiduronic acid  (EXP,ISO)
17beta-estradiol 3-benzoate  (ISO)
1H-indole  (EXP)
2'-(4-ethoxyphenyl)-5-(4-methylpiperazin-1-yl)-2,5'-bibenzimidazole  (EXP,ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-tribromophenol  (ISO)
2,4,6-trinitrobenzenesulfonic acid  (ISO)
2,8-bis-Trifluoromethyl-4-quinoline carboxylic acid  (EXP)
2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino\}-2-(propan-2-yl)pentanenitrile  (EXP,ISO)
2-(4-iodo-2,5-dimethoxyphenyl)-1-methylethylamine  (EXP)
2-[4-[3-[2-(trifluoromethyl)-9-thioxanthenylidene]propyl]-1-piperazinyl]ethanol  (EXP)
2-acetamidofluorene  (EXP,ISO)
2-butan-2-yl-4-[4-[4-[4-[[2-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-1,2,4-triazol-3-one  (EXP)
2-deoxy-D-glucose  (EXP)
2-methyl-1H-indole  (EXP)
2-nitrofluorene  (ISO)
2-trans,6-trans,10-trans-geranylgeranyl diphosphate  (ISO)
22,23-dihydroavermectin B1a  (EXP)
26-hydroxycholesterol  (EXP)
3',4',7-trihydroxyisoflavone  (EXP)
3,3',4,4'-tetrachlorobiphenyl  (ISO)
3,3',5,5'-tetrabromobisphenol A  (EXP,ISO)
3,3'-diindolylmethane  (EXP)
3,4-Dihydro-8-hydroxy-3-(3-hydroxy-4-methoxyphenyl)-1H-2-benzopyran-1-one  (EXP)
3,4-Methylenedioxyamphetamine  (EXP)
3,4-methylenedioxymethamphetamine  (EXP)
3,5-diethoxycarbonyl-1,4-dihydrocollidine  (ISO)
3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide  (EXP)
3-chloropropane-1,2-diol  (ISO)
3-methylcholanthrene  (ISO)
4'-epidoxorubicin  (EXP,ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (EXP)
5,6-dichloro-1-beta-D-ribofuranosyl-1H-benzimidazole  (EXP)
5,6-dichlorobenzimidazole riboside  (EXP)
5-aza-2'-deoxycytidine  (EXP)
5-fluorouracil  (EXP)
5-Hydroxyflavone  (EXP)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (EXP,ISO)
5-Methoxyflavone  (EXP)
5-methoxypsoralen  (EXP)
6-bromoindirubin-3'-oxime  (EXP,ISO)
6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide  (EXP)
6-chloro-5-(2,3-dichlorophenoxy)-2-(methylthio)-1H-benzimidazole  (ISO)
6-propyl-2-thiouracil  (ISO)
6alpha-methylprednisolone  (EXP)
8-(4-chlorophenylthio)-cAMP  (ISO)
abamectin  (EXP,ISO)
abietic acid  (EXP)
acenocoumarol  (EXP)
acetochlor  (EXP)
acetylsalicylic acid  (EXP,ISO)
aconitine  (EXP,ISO)
acrylamide  (EXP)
actinomycin D  (EXP,ISO)
afimoxifene  (EXP)
aflatoxin B1  (EXP,ISO)
alachlor  (EXP)
aldehydo-D-glucose  (EXP)
aldosterone  (EXP)
aliskiren  (ISO)
all-trans-retinoic acid  (EXP)
all-trans-retinol  (ISO)
alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosylceramide  (EXP)
alpha-tocotrienol  (EXP)
amiodarone  (EXP,ISO)
amitriptyline  (ISO)
ammonium chloride  (ISO)
Amorphigenin  (EXP,ISO)
amphetamine  (ISO)
amphotericin B  (ISO)
ampicillin  (ISO)
amprenavir  (EXP)
anandamide  (EXP)
anthra[1,9-cd]pyrazol-6(2H)-one  (EXP,ISO)
apocynin  (ISO)
aristolochic acid A  (EXP)
arsane  (EXP)
arsenic atom  (EXP)
arsenous acid  (EXP)
atazanavir sulfate  (EXP)
atorvastatin calcium  (EXP,ISO)
ATP  (EXP,ISO)
auraptene  (EXP)
avermectin  (ISO)
azathioprine  (EXP)
azelastine  (EXP)
Azidopine  (EXP)
Azoxymethane  (ISO)
baicalein  (EXP)
barnidipine  (EXP)
beclomethasone  (EXP)
benidipine  (EXP)
benzbromarone  (ISO)
benzene  (EXP)
benzo[a]pyrene  (EXP,ISO)
benzo[b]fluoranthene  (ISO)
benzo[e]pyrene  (EXP)
Benzo[k]fluoranthene  (EXP,ISO)
benzoylaconine  (EXP)
benzoylhypaconine  (EXP)
benzoylmesaconine  (EXP)
bepridil  (EXP)
berberine  (ISO)
bergomottin  (EXP)
beryllium difluoride  (EXP)
beta-pinene  (EXP)
beta-tocotrienol  (EXP)
betulin  (EXP)
biochanin A  (EXP)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bis-4-nitrophenyl phosphate  (ISO)
bisoprolol  (EXP)
bisphenol A  (EXP,ISO)
bisphenol AF  (EXP)
Bisphenol B  (EXP)
bortezomib  (EXP,ISO)
bosentan  (EXP)
bromobenzene  (ISO)
bromocriptine  (ISO)
budesonide  (EXP)
bufalin  (EXP)
buta-1,3-diene  (ISO)
butanal  (EXP)
Butylbenzyl phthalate  (EXP)
butyric acid  (EXP)
cadmium atom  (EXP,ISO)
cadmium dichloride  (EXP,ISO)
calcein  (EXP,ISO)
calcein am  (EXP,ISO)
calcitriol  (EXP,ISO)
calcium atom  (EXP)
calcium(0)  (EXP)
camptothecin  (EXP)
cannabidiol  (ISO)
capsaicin  (EXP,ISO)
captan  (ISO)
carbamazepine  (EXP,ISO)
carbon nanotube  (EXP,ISO)
carboplatin  (EXP)
cardenolides  (EXP)
carmustine  (EXP)
carvedilol  (EXP,ISO)
celecoxib  (EXP,ISO)
cepharanthine  (EXP)
cerivastatin  (EXP)
cetirizine  (EXP)
chenodeoxycholic acid  (EXP)
chlorambucil  (EXP)
chlordecone  (EXP)
chloroform  (EXP,ISO)
chlorohydrocarbon  (EXP)
chloroprene  (ISO)
chloroquine  (EXP,ISO)
chlorpromazine  (EXP)
chlorpyrifos  (EXP,ISO)
chlorpyrifos-methyl  (EXP)
cholic acid  (ISO)
choline  (ISO)
chrysene  (EXP)
chrysin  (EXP,ISO)
chrysin 5,7-dimethyl ether  (EXP)
Ciclesonide  (EXP)
cilastatin  (EXP)
cinchonine  (EXP)
ciprofibrate  (ISO)
cisplatin  (EXP,ISO)
citronellal  (EXP)
citronellol  (EXP)
clofibrate  (ISO)
clomipramine  (ISO)
clopidogrel  (EXP,ISO)
closantel  (ISO)
clotrimazole  (EXP,ISO)
clozapine  (EXP,ISO)
cobalt atom  (EXP)
cobalt dichloride  (EXP,ISO)
colforsin daropate hydrochloride  (EXP)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
coptisine  (ISO)
cortisol  (EXP)
costunolide  (EXP)
crizotinib  (EXP)
crocidolite asbestos  (EXP)
cucurbitacin I  (EXP)
curcumin  (EXP,ISO)
cyanocob(III)alamin  (EXP)
cyazofamid  (EXP)
cycloheximide  (EXP,ISO)
cyclophosphamide  (EXP,ISO)
cyclosporin A  (EXP,ISO)
cylindrospermopsin  (EXP)
Cymarin  (EXP)
cyproconazole  (ISO)
cytarabine  (EXP)
D-cycloserine  (EXP)
D-glucose  (EXP)
D-mannitol  (ISO)
daidzein  (EXP)
daunorubicin  (EXP,ISO)
DDE  (EXP,ISO)
DDT  (EXP,ISO)
delta-tocotrienol  (EXP)
deoxycholic acid  (EXP)
deoxynivalenol  (EXP)
desloratadine  (EXP)
Desmethylazelastine  (EXP)
dexamethasone  (EXP,ISO)
dextran sulfate  (ISO)
dextropropoxyphene  (ISO)
diallyl disulfide  (EXP)
Diallyl sulfide  (EXP)
diallyl trisulfide  (EXP)
diarsenic trioxide  (EXP)
diazinon  (EXP,ISO)
dibenz[a,h]anthracene  (ISO)
dibenziodolium  (ISO)
dibenzo[a,l]pyrene  (EXP)
diclofenac  (EXP,ISO)
dicrotophos  (EXP)
Dicyclohexyl phthalate  (ISO)
dieldrin  (EXP)
diethylstilbestrol  (EXP)
digitoxin  (EXP)
digoxigenin  (EXP)
digoxin  (EXP,ISO)
diltiazem  (EXP)
dimethomorph  (EXP)
dimethyl sulfoxide  (EXP)
dimethylarsinic acid  (ISO)
dioscin  (EXP,ISO)
dioxygen  (EXP)
diphenyl(4-piperidinyl)methanol  (EXP)
disulfiram  (EXP)
domperidone  (EXP)
Doramectin  (EXP,ISO)
dorsomorphin  (EXP)
doxazosin  (EXP)
doxepin  (ISO)
doxorubicin  (EXP,ISO)
doxycycline  (EXP)
efonidipine hydrochloride  (EXP)
emamectin  (EXP,ISO)
emodin  (EXP,ISO)
enasidenib  (EXP)
endosulfan  (EXP)
epinastine  (ISO)
epoxiconazole  (ISO)
eprinomectin  (ISO)
eriodictyol  (EXP)
erythromycin A  (EXP,ISO)
erythromycin estolate  (ISO)
erythrosin B  (EXP)
estriol  (EXP)
estriol 16-O-(beta-D-glucuronide)  (ISO)
estrone  (EXP)
ethanol  (EXP,ISO)
etoposide  (EXP)
everolimus  (EXP,ISO)
Evodiamine  (EXP)
fenofibrate  (EXP)
fenoxycarb  (EXP)
fentanyl  (EXP,ISO)
fenvalerate  (EXP,ISO)
ferrostatin-1  (EXP)
Fexofenadine hydrochloride  (EXP,ISO)
fipronil  (ISO)
flavone  (EXP)
flavonol  (EXP)
fluoxetine  (ISO)
flupenthixol  (EXP)
flutamide  (EXP,ISO)
fluticasone  (EXP)
fluvoxamine  (ISO)
folic acid  (ISO)
folpet  (ISO)
formaldehyde  (EXP)
formononetin  (EXP,ISO)
fulvestrant  (EXP,ISO)
fumonisin B1  (EXP,ISO)
fusidic acid  (EXP)
gabapentin  (EXP)
galangin  (EXP)
gallic acid  (EXP)
gallocatechin  (ISO)
gamma-hexachlorocyclohexane  (EXP)
gamma-terpinene  (EXP)
geldanamycin  (EXP)
gemcitabine  (EXP)
geneticin  (EXP)
genistein  (EXP,ISO)
gentamycin  (ISO)
gingerol  (EXP)
Ginkgoic acid  (EXP)
Ginkgolide A  (EXP)
ginkgolide B  (EXP)
ginsenoside F2  (EXP)
glabridin  (EXP)
glafenine  (ISO)
glucose  (EXP)
glutathione  (EXP)
glycitein  (EXP)
glycochenodeoxycholic acid  (EXP)
glycocholic acid  (EXP)
glycodeoxycholic acid  (EXP)
glycyrrhetinate  (EXP)
glycyrrhetinic acid  (EXP)
glyphosate  (EXP)
Goe 6976  (ISO)
gold atom  (EXP)
gold(0)  (EXP)
graphite  (ISO)
griseofulvin  (ISO)
GTP  (EXP)
GW 7647  (EXP,ISO)
haloperidol  (EXP)
heptachlor  (EXP)
huperzine A  (EXP,ISO)
hyaluronic acid  (EXP)
hydramethylnon  (EXP)
hydrogen peroxide  (EXP)
Hypaconitine  (EXP,ISO)
hyperforin  (EXP)
hypericin  (EXP)
ifosfamide  (EXP)
imipenem hydrate  (ISO)
imipramine  (ISO)
indole-3-acetamide  (EXP)
indole-3-methanol  (EXP,ISO)
irinotecan  (EXP,ISO)
iron(III) nitrilotriacetate  (EXP)
isoprenaline  (ISO)
isorhamnetin  (EXP)
Isosafrole  (EXP)
isotretinoin  (EXP)
isovitexin  (EXP)
itraconazole  (EXP)
ivermectin  (EXP,ISO)
kaempferide  (EXP)
kaempferol  (EXP)
kainic acid  (ISO)
kenpaullone  (EXP)
ketamine  (ISO)
ketoconazole  (EXP,ISO)
KN-93  (EXP)
KT 5720  (EXP)
kuwanone G  (ISO)
L-ascorbic acid  (EXP,ISO)
L-ethionine  (ISO)
L-methionine  (ISO)
lamotrigine  (EXP)
lansoprazole  (EXP)
lapatinib  (EXP)
LCL161  (EXP)
lead(0)  (EXP)
levetiracetam  (EXP,ISO)
levonorgestrel  (EXP)
lipoic acid  (ISO)
lipopolysaccharide  (EXP,ISO)
lithium chloride  (EXP)
lithocholic acid  (EXP)
lomustine  (EXP)
loperamide  (EXP,ISO)
loratadine  (EXP,ISO)
lovastatin  (EXP)
luteolin  (EXP)
LY294002  (EXP,ISO)
macitentan  (EXP)
magnesium atom  (EXP)
malonaldehyde  (ISO)
manganese atom  (EXP,ISO)
manganese(0)  (EXP,ISO)
manganese(II) chloride  (ISO)
mangiferin  (EXP)
manidipine  (EXP)
mebendazole  (EXP)
MeIQx  (ISO)
melatonin  (ISO)
meloxicam  (EXP)
mercury atom  (EXP)
mercury(0)  (EXP)
Mesaconitine  (EXP,ISO)
metazachlor  (EXP)
metformin  (EXP)
methadone  (EXP)
methamphetamine  (ISO)
methapyrilene  (ISO)
methotrexate  (EXP,ISO)
methoxsalen  (EXP)
methoxyfenozide  (EXP)
methyl 2-methylpropyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate  (EXP)
methylarsonic acid  (ISO)
metiram  (EXP)
metoclopramide  (ISO)
metolachlor  (EXP)
metronidazole  (ISO)
miconazole  (EXP,ISO)
microcystin-LR  (ISO)
midazolam  (EXP)
midostaurin  (EXP)
mifepristone  (EXP,ISO)
milbemycin  (EXP,ISO)
miltefosine  (EXP)
mirtazapine  (ISO)
mitomycin C  (EXP)
Mitotane  (EXP)
mitoTracker Green FM  (EXP)
mitoxantrone  (EXP)
MK 571  (EXP)
mometasone furoate  (EXP)
morin  (EXP)
morphine  (EXP,ISO)
myricetin  (EXP)
N(alpha)-acetyl-L-arginine  (EXP)
N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide  (EXP)
N-\{6-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]hexanoyl\}sphingosine  (EXP)
N-acetyl-L-cysteine  (EXP,ISO)
N-acetylsphingosine  (EXP)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (EXP,ISO)
N-desethylamiodarone  (EXP)
N-ethylmaleimide  (EXP)
N-hydroxy-PhIP  (ISO)
N-nitrosodiethylamine  (ISO)
N-nitrosodimethylamine  (ISO)
naloxone  (ISO)
naphthalene  (EXP)
naproxen  (EXP)
naringin  (EXP)
nelfinavir  (EXP)
Nemadectin  (EXP)
neomycin  (ISO)
nevirapine  (ISO)
nicardipine  (EXP)
nickel atom  (EXP)
nickel dichloride  (ISO)
nicorandil  (ISO)
nifedipine  (EXP)
nilotinib  (EXP)
Nilvadipine  (EXP)
nimesulide  (EXP)
nisoldipine  (EXP)
nobiletin  (EXP)
Nonylphenol  (ISO)
norathyriol  (EXP)
norethisterone  (EXP)
nortriptyline  (EXP,ISO)
notoginsenoside R1  (EXP,ISO)
NS-398  (EXP)
Nutlin-3  (EXP)
ochratoxin A  (ISO)
okadaic acid  (EXP)
olanzapine  (EXP,ISO)
oleoyl ethanolamide  (EXP)
oltipraz  (EXP,ISO)
Omadacycline  (EXP)
omeprazole  (EXP,ISO)
ophiobolin A  (EXP)
organophosphorus compound  (EXP)
oroxylin A  (EXP)
ouabain  (EXP)
oxycodone  (ISO)
ozone  (ISO)
paclitaxel  (EXP,ISO)
paliperidone palmitate  (EXP,ISO)
palmatine  (ISO)
palmitoyl ethanolamide  (EXP)
paracetamol  (EXP,ISO)
paraquat  (EXP,ISO)
parathion  (EXP)
paroxetine  (ISO)
parthenolide  (EXP)
PCB138  (ISO)
pentobarbital  (ISO)
Pentoxifylline  (EXP)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (EXP,ISO)
peruvoside  (EXP)
phalloidin  (ISO)
phenobarbital  (EXP,ISO)
phenols  (EXP)
phenytoin  (EXP,ISO)
PhIP  (ISO)
phorbol 13-acetate 12-myristate  (EXP)
phosalone  (EXP)
phosphatidylcholine  (EXP)
phosphoramide mustard  (ISO)
pimecrolimus  (EXP)
pinostrobin  (EXP)
pioglitazone  (EXP)
piperine  (EXP)
piperonyl butoxide  (ISO)
pirinixic acid  (EXP,ISO)
pitavastatin  (EXP)
pitavastatin(1-)  (EXP)
poly(ethene-1,2-diyl) macromolecule  (EXP)
pravastatin  (EXP)
prazosin  (EXP,ISO)
prednisone  (EXP,ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
prochloraz  (ISO)
progesterone  (EXP)
propiconazole  (EXP,ISO)
propranolol  (EXP)
Proscillaridin  (EXP)
Prulifloxacin  (ISO)
psorospermin  (EXP)
puerarin  (EXP)
puromycin  (EXP,ISO)
pyrrolidine dithiocarbamate  (ISO)
quercetin  (EXP)
quercitrin  (EXP)
quetiapine fumarate  (EXP)
quinacrine  (EXP)
quinidine  (EXP,ISO)
quinine  (EXP)
quinpirole  (ISO)
rac-3,4-methylenedioxy-N-ethylamphetamine  (EXP)
raloxifene  (EXP)
razoxane  (EXP)
rescinnamine  (EXP)
reserpine  (EXP,ISO)
resveratrol  (EXP,ISO)
rhodamine 123  (EXP,ISO)
riddelliine  (ISO)
rifabutin  (EXP)
rifampicin  (EXP,ISO)
rifaximin  (EXP)
risperidone  (EXP,ISO)
ritonavir  (EXP)
romidepsin  (EXP)
rose bengal  (EXP)
rotenone  (EXP,ISO)
rubimaillin  (EXP)
rutin  (EXP)
Salidroside  (EXP)
saquinavir  (EXP,ISO)
sarin  (EXP)
saxitoxin  (ISO)
schaftoside  (EXP)
sciadopitysin  (EXP)
scopolamine  (ISO)
SDZ PSC 833  (EXP,ISO)
Secomilbemycin D  (EXP)
Selamectin  (ISO)
senecionine  (ISO)
sepantronium  (EXP)
sertraline  (EXP)
sesquiterpene  (EXP)
sevoflurane  (ISO)
sildenafil citrate  (ISO)
silibinin  (EXP)
simvastatin  (EXP)
sinensetin  (EXP)
sirolimus  (EXP)
SNX-2112  (EXP)
sodium arsenite  (EXP,ISO)
sodium azide  (EXP)
sodium chloride  (ISO)
sodium dichromate  (ISO)
sorafenib  (EXP)
sotalol  (EXP)
spinosad  (EXP)
spiperone  (ISO)
spironolactone  (EXP)
stavudine  (EXP)
strophanthidin  (EXP)
succimer  (EXP)
sulconazole  (EXP)
sulforaphane  (EXP,ISO)
sulpiride  (EXP)
sunitinib  (ISO)
T-2 toxin  (ISO)
tacrolimus hydrate  (EXP)
tamarixetin  (EXP)
tamoxifen  (EXP,ISO)
tangeretin  (EXP)
Tariquidar  (EXP)
tartrazine  (EXP)
taurocholic acid  (ISO)
taxane  (EXP)
tebufenozide  (EXP)
Technetium tc 99m sestamibi  (EXP,ISO)
tectochrysin  (EXP)
temozolomide  (EXP)
terameprocol  (EXP)
Terfenadine  (EXP)
terpinolene  (EXP)
tert-butyl hydroperoxide  (ISO)
tetrachloroethene  (ISO)
tetrachloromethane  (EXP,ISO)
tetracycline  (ISO)
thalidomide  (EXP)
thapsigargin  (EXP)
thioacetamide  (ISO)
tiagabine  (ISO)
tipifarnib  (EXP)
titanium dioxide  (EXP,ISO)
Tocophersolan  (EXP)
tolbutamide  (EXP)
toluene  (ISO)
topiramate  (ISO)
topotecan  (EXP)
trabectedin  (ISO)
tralkoxydim  (EXP)
traumatic acid  (EXP,ISO)
triadimefon  (EXP,ISO)
triamcinolone acetonide  (ISO)
triamterene  (ISO)
tributylstannane  (ISO)
trichloroethene  (ISO)
trichostatin A  (EXP)
triclosan  (EXP)
trifluoperazine  (EXP)
trimethylarsine oxide  (ISO)
triphenyl phosphate  (EXP,ISO)
Triptolide  (ISO)
troglitazone  (EXP)
troleandomycin  (EXP,ISO)
trospium chloride  (EXP)
Tryptanthrine  (EXP)
tunicamycin  (EXP)
urethane  (EXP)
ursodeoxycholic acid  (EXP,ISO)
ursolic acid  (EXP)
valdecoxib  (ISO)
valproic acid  (EXP,ISO)
vancomycin  (EXP,ISO)
veliparib  (EXP)
venetoclax  (EXP)
venlafaxine hydrochloride  (EXP,ISO)
verapamil  (EXP,ISO)
vincaleukoblastine  (EXP,ISO)
vincristine  (EXP,ISO)
vorinostat  (EXP,ISO)
warfarin  (EXP,ISO)
withaferin A  (EXP)
xanthenes  (EXP,ISO)
yohimbine  (EXP)
zearalenone  (ISO)
zidovudine  (EXP)
zinc atom  (EXP)
zinc dichloride  (EXP,ISO)
zinc(0)  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
carboxylic acid transmembrane transport  (IMP)
cellular hyperosmotic salinity response  (ISO)
cellular response to alkaloid  (ISO)
cellular response to antibiotic  (ISO)
cellular response to borneol  (ISO)
cellular response to dexamethasone stimulus  (ISO)
cellular response to estradiol stimulus  (ISO)
cellular response to external biotic stimulus  (ISO)
cellular response to L-glutamate  (ISO)
cellular response to lipopolysaccharide  (ISO)
cellular response to mycotoxin  (ISO)
cellular response to nonylphenol  (ISO)
cellular response to tumor necrosis factor  (ISO)
ceramide translocation  (IBA,IDA)
circadian rhythm  (ISO)
daunorubicin transport  (ISO)
establishment of blood-brain barrier  (ISO)
establishment of blood-retinal barrier  (ISO)
export across plasma membrane  (IDA,IMP)
female pregnancy  (ISO)
G2/M transition of mitotic cell cycle  (IDA)
hormone transport  (ISO)
intestinal absorption  (ISO)
lactation  (ISO)
lipid transport  (IEA)
maintenance of blood-brain barrier  (ISO)
negative regulation of sensory perception of pain  (ISO)
phospholipid translocation  (IBA,IDA)
placenta development  (ISO)
positive regulation of establishment of Sertoli cell barrier  (ISO)
positive regulation of response to drug  (ISO)
protein localization to bicellular tight junction  (ISO)
regulation of chloride transport  (IMP)
regulation of intestinal absorption  (ISO)
response to alcohol  (ISO)
response to antineoplastic agent  (ISO)
response to cadmium ion  (ISO)
response to codeine  (ISO)
response to cyclosporin A  (ISO)
response to dexamethasone  (ISO)
response to estradiol  (ISO)
response to glucagon  (ISO)
response to glycoside  (ISO)
response to hypoxia  (ISO)
response to L-glutamate  (ISO)
response to lipopolysaccharide  (ISO)
response to mycotoxin  (ISO)
response to nutrient levels  (ISO)
response to progesterone  (ISO)
response to quercetin  (ISO)
response to thyroxine  (ISO)
response to vitamin A  (ISO)
response to vitamin D  (ISO)
response to xenobiotic stimulus  (ISO,TAS)
stem cell proliferation  (IMP)
terpenoid transport  (ISS)
transepithelial transport  (IDA,IMP)
transmembrane transport  (IEA,ISO,TAS)
transport across blood-brain barrier  (NAS)
xenobiotic detoxification by transmembrane export across the plasma membrane  (IDA,IGI,IMP,ISO)
xenobiotic metabolic process  (TAS)
xenobiotic transport across blood-brain barrier  (IC,IMP,ISO,ISS)

Cellular Component

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
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2. A Common mdr1 Gene Polymorphism is Associated With Changes in Linezolid Clearance. Allegra S, etal., Ther Drug Monit. 2018 Oct;40(5):602-609. doi: 10.1097/FTD.0000000000000536.
3. The role of multidrug resistance-1 (MDR1) variants in response to fexofenadine among Jordanians. Alzoubi KH, etal., Int J Clin Pharmacol Ther. 2013 Nov;51(11):880-7. doi: 10.5414/CP201968.
4. Association of genotypes and haplotypes of multi-drug transporter genes ABCB1 and ABCG2 with clinical response to imatinib mesylate in chronic myeloid leukemia patients. Au A, etal., Biomed Pharmacother. 2014 Apr;68(3):343-9. doi: 10.1016/j.biopha.2014.01.009. Epub 2014 Feb 7.
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9. Meta-analysis of contribution of genetic polymorphisms in drug-metabolizing enzymes or transporters to axitinib pharmacokinetics. Brennan M, etal., Eur J Clin Pharmacol. 2012 May;68(5):645-55. Epub 2011 Dec 15.
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11. Nephroblastoma: multidrug-resistance P-glycoprotein expression in tumor cells and intratumoral capillary endothelial cells. Camassei FD, etal., Am J Clin Pathol. 2002 Mar;117(3):484-90.
12. ABCB1 genotypes predict cyclosporine-related adverse events and kidney allograft outcome. Cattaneo D, etal., J Am Soc Nephrol. 2009 Jun;20(6):1404-15. Epub 2009 May 21.
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17. ABCB1 genetic variability and methadone dosage requirements in opioid-dependent individuals. Coller JK, etal., Clin Pharmacol Ther. 2006 Dec;80(6):682-90. doi: 10.1016/j.clpt.2006.09.011.
18. Pharmacogenetic analysis of hepatitis C virus related mixed cryoglobulinemia. Cusato J, etal., Pharmacogenomics. 2017 May;18(7):607-611. doi: 10.2217/pgs-2016-0040. Epub 2017 Apr 28.
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21. Lack of an effect of CYP3A4 and MDR1 gene polymorphisms on colchicine pharmacogenetics in the treatment of Familial Mediterranean fever. Dogruer D, etal., Genet Mol Res. 2013 Jan 24;12(3):3521-8. doi: 10.4238/2013.January.24.2.
22. Hepatobiliary damage and changes in hepatic gene expression caused by the antitumor drug ecteinascidin-743 (ET-743) in the female rat. Donald S, etal., Cancer Res 2002 Aug 1;62(15):4256-62.
23. Influence of intermittent hypoxia on myocardial and hepatic P-glycoprotein expression in a rodent model. Dopp JM, etal., Pharmacotherapy. 2009 Apr;29(4):365-72.
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25. Higher frequency of C.3435 of the ABCB1 gene in patients with tramadol dependence disorder. Enabah D, etal., Am J Drug Alcohol Abuse. 2014 Jul;40(4):317-20. doi: 10.3109/00952990.2014.925468. Epub 2014 Jun 20.
26. Synergistic interaction of ABCB1 and ABCG2 polymorphisms predicts the prevalence of toxic encephalopathy during anticancer chemotherapy. Erdilyi DJ, etal., Pharmacogenomics J. 2008 Oct;8(5):321-7.
27. ABCB1 polymorphism is associated with atorvastatin-induced liver injury in Japanese population. Fukunaga K, etal., BMC Genet. 2016 Jun 13;17(1):79. doi: 10.1186/s12863-016-0390-5.
28. Common ABCB1 polymorphisms in Greek patients with chronic hepatitis C infection: A comparison with hyperlipidemic patients and the general population. Gbandi E, etal., Pharmacol Rep. 2016 Apr;68(2):476-82. doi: 10.1016/j.pharep.2015.10.009. Epub 2015 Nov 6.
29. Endotoxin mediated downregulation of hepatic drug transporters in HIV-1 transgenic rats. Ghoneim RH and Piquette-Miller M, Drug Metab Dispos. 2016 Mar 14. pii: dmd.115.067827.
30. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
31. Downregulation of mdr1a expression in the brain and liver during CNS inflammation alters the in vivo disposition of digoxin. Goralski KB, etal., Br J Pharmacol. 2003 May;139(1):35-48.
32. Osteitis is associated with P-glycoprotein overexpression in patients with chronic sinusitis without nasal polyps. Gunel C, etal., Am J Rhinol Allergy. 2014 Mar-Apr;28(2):99-102. doi: 10.2500/ajra.2014.28.4011.
33. P-glycoprotein induction by breast milk attenuates intestinal inflammation in experimental necrotizing enterocolitis. Guner YS, etal., Lab Invest. 2011 Nov;91(11):1668-79. doi: 10.1038/labinvest.2011.113. Epub 2011 Jul 25.
34. Genetic and epigenetic changes in host ABCB1 influences malaria susceptibility to Plasmodium falciparum. Gupta H, etal., PLoS One. 2017 Apr 19;12(4):e0175702. doi: 10.1371/journal.pone.0175702. eCollection 2017.
35. Associations of ABCB1, ABCC2, and ABCG2 polymorphisms with irinotecan-pharmacokinetics and clinical outcome in patients with advanced non-small cell lung cancer. Han JY, etal., Cancer. 2007 Jul 1;110(1):138-47.
36. Molecular mechanism of altered ezetimibe disposition in nonalcoholic steatohepatitis. Hardwick RN, etal., Drug Metab Dispos. 2012 Mar;40(3):450-60. doi: 10.1124/dmd.111.041095. Epub 2011 Nov 23.
37. Changes of Absorptive and Secretory Transporting System of (1 --> 3) beta-D-glucan Based on Efflux Transporter in Indomethacin-induced Rat. Iida A, etal., Eur J Drug Metab Pharmacokinet. 2015 Mar;40(1):29-38. doi: 10.1007/s13318-014-0174-0. Epub 2014 Feb 11.
38. Verapamil and rifampin effect on p-glycoprotein expression in hepatocellular carcinoma. Jalali A, etal., Jundishapur J Nat Pharm Prod. 2014 Oct 10;9(4):e17741. eCollection 2014 Nov.
39. PSC 833, an inhibitor of P-glycoprotein inhibits 1,2-dimethylhydrazine-induced colorectal carcinogenesis in male Fischer F344 rats. Kankesan J, etal., Anticancer Res. 2006 Mar-Apr;26(2A):995-9.
40. Effects of Genetic Polymorphisms of Cytochrome P450 Enzymes and MDR1 Transporter on Pantoprazole Metabolism and Helicobacter pylori Eradication. Karaca RO, etal., Basic Clin Pharmacol Toxicol. 2017 Feb;120(2):199-206. doi: 10.1111/bcpt.12667. Epub 2016 Nov 2.
41. ABCB1 gene polymorphisms are associated with fatal intoxications involving venlafaxine but not citalopram. Karlsson L, etal., Int J Legal Med. 2013 May;127(3):579-86. doi: 10.1007/s00414-013-0849-0. Epub 2013 Mar 21.
42. The drug transporter ABCB1 c.3435C>T SNP influences artemether-lumefantrine treatment outcome. Kiaco K, etal., Malar J. 2017 Sep 21;16(1):383. doi: 10.1186/s12936-017-2006-6.
43. Prospective evaluation of the drug-metabolizing enzyme polymorphisms and toxicity profile of docetaxel in Korean patients with operable lymph node-positive breast cancer receiving adjuvant chemotherapy. Kim KP, etal., Cancer Chemother Pharmacol. 2012 May;69(5):1221-7. doi: 10.1007/s00280-011-1816-4. Epub 2012 Jan 20.
44. Inhibition of P-glycoprotein Gene Expression and Function Enhances Triptolide-induced Hepatotoxicity in Mice. Kong LL, etal., Sci Rep. 2015 Jul 2;5:11747. doi: 10.1038/srep11747.
45. The anti-inflammatory effects of inhaled corticosteroids versus anti-leukotrienes on the lymphocyte P-glycoprotein (PGP) expression in asthmatic children. Kopriva F, etal., J Asthma. 2009 May;46(4):366-70.
46. Accumulation of murine amyloid-ß mimics early Alzheimer's disease. Krohn M, etal., Brain. 2015 Aug;138(Pt 8):2370-82. doi: 10.1093/brain/awv137. Epub 2015 May 18.
47. Regional expression of multidrug resistance genes in genetically epilepsy-prone rat brain after a single audiogenic seizure. Kwan P, etal., Epilepsia. 2002 Nov;43(11):1318-23.
48. Etoposide nanocarriers suppress glioma cell growth by intracellular drug delivery and simultaneous P-glycoprotein inhibition. Lamprecht A and Benoit JP, J Control Release. 2006 May 15;112(2):208-13. Epub 2006 Feb 28.
49. Moving toward personalized medicine in the methadone maintenance treatment program: a pilot study on the evaluation of treatment responses in Taiwan. Lee HY, etal., Biomed Res Int. 2013;2013:741403. doi: 10.1155/2013/741403. Epub 2013 Dec 16.
50. Association between the c.3751G>a genetic variant of MDR1 and hepatocellular carcinoma risk in a Chinese Han population. Li XF, etal., Asian Pac J Cancer Prev. 2013;14(9):5361-5. doi: 10.7314/apjcp.2013.14.9.5361.
51. Expression of HIF-1alpha and MDR1/P-glycoprotein in refractory mesial temporal lobe epilepsy patients and pharmacoresistant temporal lobe epilepsy rat model kindled by coriaria lactone. Li Y, etal., Neurol Sci. 2014 Aug;35(8):1203-8. doi: 10.1007/s10072-014-1681-0. Epub 2014 Mar 4.
52. Impaired function and expression of P-glycoprotein in blood-brain barrier of streptozotocin-induced diabetic rats. Liu H, etal., Brain Res. 2006 Dec 6;1123(1):245-52. Epub 2006 Oct 30.
53. Impact of SNP-SNP interaction among ABCB1, ARRB2, DRD1 and OPRD1 on methadone dosage requirement in Han Chinese patients. Luo R, etal., Pharmacogenomics. 2017 Dec;18(18):1659-1670. doi: 10.2217/pgs-2017-0072. Epub 2017 Nov 27.
54. Functional induction of P-glycoprotein in the blood-brain barrier of streptozotocin-induced diabetic rats: evidence for the involvement of nuclear factor-kappaB, a nitrosative stress-sensitive transcription factor, in the regulation. Maeng HJ, etal., Drug Metab Dispos. 2007 Nov;35(11):1996-2005. Epub 2007 Jul 30.
55. Prognostic significance of multidrug-resistance protein (MDR-1) in renal clear cell carcinomas: a five year follow-up analysis. Mignogna C, etal., BMC Cancer. 2006 Dec 19;6:293.
56. P-glycoprotein (ABCB1) activity decreases raltegravir disposition in primary CD4+P-gphigh cells and correlates with HIV-1 viral load. Minuesa G, etal., J Antimicrob Chemother. 2016 Oct;71(10):2782-92. doi: 10.1093/jac/dkw215. Epub 2016 Jun 21.
57. Down-regulation of intestinal drug transporters in chronic renal failure in rats. Naud J, etal., J Pharmacol Exp Ther. 2007 Mar;320(3):978-85. Epub 2006 Nov 29.
58. MDR1, MRP1 and MRP2 genotypes and in vitro chemosensitivity in Japanese patients with colorectal adenocarcinomas. Nishioka C, etal., Kobe J Med Sci. 2004;50(5-6):181-8.
59. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
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PMID:25799371   PMID:25801244   PMID:25802484   PMID:25809606   PMID:25816099   PMID:25840583   PMID:25843201   PMID:25846690   PMID:25847751   PMID:25853335   PMID:25854371   PMID:25860377  
PMID:25861751   PMID:25861753   PMID:25869250   PMID:25885226   PMID:25908454   PMID:25921160   PMID:25921280   PMID:25921289   PMID:25930089   PMID:25930120   PMID:25940551   PMID:25959925  
PMID:25960213   PMID:25964202   PMID:25968898   PMID:25986174   PMID:25987242   PMID:25987565   PMID:25988710   PMID:25989890   PMID:25995454   PMID:25997249   PMID:26006083   PMID:26025411  
PMID:26026084   PMID:26045821   PMID:26057472   PMID:26062728   PMID:26071279   PMID:26086643   PMID:26107220   PMID:26109419   PMID:26124005   PMID:26125482   PMID:26125837   PMID:26136502  
PMID:26153782   PMID:26154535   PMID:26158764   PMID:26159621   PMID:26176181   PMID:26184955   PMID:26186194   PMID:26198313   PMID:26208431   PMID:26208548   PMID:26208549   PMID:26211578  
PMID:26213157   PMID:26219569   PMID:26219897   PMID:26220385   PMID:26228923   PMID:26244574   PMID:26261589   PMID:26278584   PMID:26281846   PMID:26286835   PMID:26288241   PMID:26299618  
PMID:26317651   PMID:26319048   PMID:26327575   PMID:26338742   PMID:26351321   PMID:26353179   PMID:26354214   PMID:26362473   PMID:26376376   PMID:26379408   PMID:26381710   PMID:26400323  
PMID:26407213   PMID:26421491   PMID:26438079   PMID:26450467   PMID:26460589   PMID:26463665   PMID:26489634   PMID:26503809   PMID:26507655   PMID:26515462   PMID:26517909   PMID:26517914  
PMID:26517917   PMID:26517918   PMID:26531821   PMID:26535684   PMID:26546461   PMID:26556876   PMID:26589910   PMID:26590417   PMID:26595166   PMID:26596829   PMID:26598078   PMID:26601947  
PMID:26604430   PMID:26625351   PMID:26632382   PMID:26638586   PMID:26652611   PMID:26664259   PMID:26686578   PMID:26694653   PMID:26695516   PMID:26700668   PMID:26704667   PMID:26704739  
PMID:26705892   PMID:26715450   PMID:26717965   PMID:26745103   PMID:26757307   PMID:26764117   PMID:26782761   PMID:26784512   PMID:26790444   PMID:26790551   PMID:26799285   PMID:26799497  
PMID:26810690   PMID:26820614   PMID:26823755   PMID:26823873   PMID:26829120   PMID:26838221   PMID:26843476   PMID:26850595   PMID:26856709   PMID:26857559   PMID:26857783   PMID:26876203  
PMID:26895184   PMID:26934120   PMID:26938523   PMID:26948503   PMID:27013200   PMID:27031494   PMID:27037060   PMID:27039718   PMID:27040946   PMID:27043281   PMID:27045516   PMID:27058921  
PMID:27060927   PMID:27082231   PMID:27117502   PMID:27133047   PMID:27137881   PMID:27154635   PMID:27159830   PMID:27169328   PMID:27176642   PMID:27177126   PMID:27180050   PMID:27182942  
PMID:27190212   PMID:27256377   PMID:27258931   PMID:27270784   PMID:27284014   PMID:27286705   PMID:27287205   PMID:27288795   PMID:27294449   PMID:27295567   PMID:27300692   PMID:27308662  
PMID:27309038   PMID:27321806   PMID:27323187   PMID:27367030   PMID:27378609   PMID:27391700   PMID:27394416   PMID:27405085   PMID:27409663   PMID:27426203   PMID:27442114   PMID:27453281  
PMID:27456824   PMID:27479651   PMID:27499034   PMID:27503662   PMID:27503929   PMID:27517323   PMID:27527855   PMID:27533339   PMID:27534401   PMID:27536777   PMID:27538645   PMID:27545861  
PMID:27553832   PMID:27564555   PMID:27580695   PMID:27600024   PMID:27602881   PMID:27603561   PMID:27604859   PMID:27605311   PMID:27612427   PMID:27641736   PMID:27649127   PMID:27649668  
PMID:27662649   PMID:27678410   PMID:27689338   PMID:27706454   PMID:27706688   PMID:27739315   PMID:27749554   PMID:27754360   PMID:27770655   PMID:27780727   PMID:27821506   PMID:27835872  
PMID:27840996   PMID:27854072   PMID:27854515   PMID:27864369   PMID:27883323   PMID:27886333   PMID:27893182   PMID:27893429   PMID:27897267   PMID:27897269   PMID:27918128   PMID:27931149  
PMID:27941276   PMID:27960630   PMID:27995666   PMID:27996183   PMID:27999186   PMID:28025146   PMID:28036387   PMID:28039704   PMID:28050891   PMID:28052008   PMID:28063968   PMID:28074308  
PMID:28077325   PMID:28079463   PMID:28094348   PMID:28111265   PMID:28132103   PMID:28135009   PMID:28137267   PMID:28145501   PMID:28151874   PMID:28153721   PMID:28154898   PMID:28165634  
PMID:28189737   PMID:28206854   PMID:28207188   PMID:28252574   PMID:28259962   PMID:28260091   PMID:28260112   PMID:28274756   PMID:28283574   PMID:28284049   PMID:28289864   PMID:28289867  
PMID:28290618   PMID:28299396   PMID:28330783   PMID:28340578   PMID:28353592   PMID:28358418   PMID:28358842   PMID:28367681   PMID:28378058   PMID:28385544   PMID:28388599   PMID:28389777  
PMID:28405849   PMID:28408210   PMID:28411377   PMID:28427190   PMID:28447211   PMID:28450237   PMID:28476838   PMID:28479352   PMID:28492560   PMID:28509582   PMID:28514285   PMID:28514442  
PMID:28534442   PMID:28549670   PMID:28554760   PMID:28572401   PMID:28576750   PMID:28587984   PMID:28590019   PMID:28608314   PMID:28614221   PMID:28614261   PMID:28615105   PMID:28616661  
PMID:28630426   PMID:28676669   PMID:28678049   PMID:28698198   PMID:28707077   PMID:28713943   PMID:28736028   PMID:28757552   PMID:28759738   PMID:28776352   PMID:28791369   PMID:28792917  
PMID:28805879   PMID:28825695   PMID:28833323   PMID:28836054   PMID:28837897   PMID:28844709   PMID:28845766   PMID:28858994   PMID:28859099   PMID:28867064   PMID:28888211   PMID:28917442  
PMID:28952408   PMID:28970358   PMID:29016899   PMID:29023140   PMID:29098941   PMID:29107111   PMID:29113667   PMID:29151072   PMID:29170124   PMID:29171106   PMID:29177954   PMID:29187454  
PMID:29198163   PMID:29210323   PMID:29222397   PMID:29232306   PMID:29252093   PMID:29261027   PMID:29262351   PMID:29282011   PMID:29305422   PMID:29314799   PMID:29316665   PMID:29318780  
PMID:29325225   PMID:29342177   PMID:29348145   PMID:29350207   PMID:29352737   PMID:29371429   PMID:29377275   PMID:29381954   PMID:29390571   PMID:29409484   PMID:29425587   PMID:29436678  
PMID:29440498   PMID:29443543   PMID:29469608   PMID:29481489   PMID:29482174   PMID:29491071   PMID:29495954   PMID:29504705   PMID:29509884   PMID:29511086   PMID:29543864   PMID:29601950  
PMID:29615122   PMID:29616858   PMID:29621396   PMID:29654270   PMID:29668471   PMID:29689707   PMID:29695404   PMID:29695635   PMID:29723928   PMID:29736778   PMID:29742496   PMID:29754150  
PMID:29777711   PMID:29791609   PMID:29848980   PMID:29885788   PMID:29901180   PMID:29921377   PMID:29937544   PMID:29938681   PMID:29948283   PMID:29951962   PMID:29956807   PMID:29971911  
PMID:29991328   PMID:29997495   PMID:30016952   PMID:30021884   PMID:30022368   PMID:30066890   PMID:30098863   PMID:30114619   PMID:30126848   PMID:30143489   PMID:30176891   PMID:30181081  
PMID:30213564   PMID:30222077   PMID:30231297   PMID:30256048   PMID:30256530   PMID:30262858   PMID:30265721   PMID:30273544   PMID:30277801   PMID:30280653   PMID:30317428   PMID:30334473  
PMID:30343695   PMID:30372807   PMID:30422888   PMID:30441975   PMID:30444043   PMID:30455395   PMID:30471066   PMID:30508724   PMID:30551694   PMID:30556139   PMID:30587068   PMID:30609256  
PMID:30622215   PMID:30623608   PMID:30632789   PMID:30639242   PMID:30710584   PMID:30725221   PMID:30729282   PMID:30760665   PMID:30765569   PMID:30779721   PMID:30786691   PMID:30794795  
PMID:30796464   PMID:30799432   PMID:30854958   PMID:30865384   PMID:30894541   PMID:30896644   PMID:30907254   PMID:30915355   PMID:30916611   PMID:30931962   PMID:30942458   PMID:30963442  
PMID:30977678   PMID:30981768   PMID:30982500   PMID:30983549   PMID:31003147   PMID:31021303   PMID:31023123   PMID:31048454   PMID:31097669   PMID:31113932   PMID:31121484   PMID:31124417  
PMID:31128980   PMID:31132291   PMID:31137684   PMID:31157746   PMID:31173253   PMID:31189171   PMID:31209929   PMID:31253208   PMID:31266056   PMID:31272852   PMID:31298164   PMID:31304590  
PMID:31307954   PMID:31311995   PMID:31323002   PMID:31335167   PMID:31346154   PMID:31412123   PMID:31512001   PMID:31539112   PMID:31562781   PMID:31571407   PMID:31574240   PMID:31585733  
PMID:31588879   PMID:31634239   PMID:31634334   PMID:31638462   PMID:31679234   PMID:31690757   PMID:31699188   PMID:31703128   PMID:31713897   PMID:31738228   PMID:31750987   PMID:31759356  
PMID:31771390   PMID:31771696   PMID:31774615   PMID:31780765   PMID:31791063   PMID:31810909   PMID:31829834   PMID:31831065   PMID:31854268   PMID:31871319   PMID:31871496   PMID:31948121  
PMID:31967866   PMID:31995728   PMID:32017076   PMID:32020017   PMID:32050000   PMID:32053102   PMID:32054883   PMID:32054924   PMID:32058310   PMID:32061787   PMID:32080102   PMID:32114419  
PMID:32124932   PMID:32125889   PMID:32127237   PMID:32134535   PMID:32141846   PMID:32155954   PMID:32198935   PMID:32203206   PMID:32206097   PMID:32222391   PMID:32243098   PMID:32247608  
PMID:32277145   PMID:32313056   PMID:32316515   PMID:32353410   PMID:32356320   PMID:32399998   PMID:32429133   PMID:32457290   PMID:32462562   PMID:32468216   PMID:32484843   PMID:32564116  
PMID:32598752   PMID:32655137   PMID:32682874   PMID:32702814   PMID:32711413   PMID:32712857   PMID:32713860   PMID:32715517   PMID:32719417   PMID:32748110   PMID:32756886   PMID:32758011  
PMID:32792062   PMID:32862511   PMID:32871888   PMID:32890316   PMID:32980890   PMID:33022784   PMID:33031417   PMID:33040624   PMID:33065613   PMID:33072207   PMID:33096057   PMID:33110235  
PMID:33125122   PMID:33125673   PMID:33129240   PMID:33159693   PMID:33167906   PMID:33222668   PMID:33232268   PMID:33244077   PMID:33252269   PMID:33256506   PMID:33275773   PMID:33289076  
PMID:33306668   PMID:33326171   PMID:33351694   PMID:33400943   PMID:33420675   PMID:33422770   PMID:33454797   PMID:33462346   PMID:33481175   PMID:33506275   PMID:33542180   PMID:33543229  
PMID:33547668   PMID:33565324   PMID:33565361   PMID:33649818   PMID:33720323   PMID:33740100   PMID:33768546   PMID:33781748   PMID:33807514   PMID:33832418   PMID:33903659   PMID:33939644  
PMID:33949294   PMID:33961781   PMID:33962209   PMID:33975019   PMID:33978213   PMID:34008992   PMID:34031441   PMID:34053421   PMID:34058179   PMID:34079125   PMID:34089489   PMID:34153010  
PMID:34161330   PMID:34260525   PMID:34270461   PMID:34280009   PMID:34304427   PMID:34346513   PMID:34347777   PMID:34349018   PMID:34362271   PMID:34375710   PMID:34411648   PMID:34440433  
PMID:34445264   PMID:34475043   PMID:34480602   PMID:34496661   PMID:34499772   PMID:34563206   PMID:34572328   PMID:34573401   PMID:34590490   PMID:34603785   PMID:34610620   PMID:34641326  
PMID:34695419   PMID:34700018   PMID:34702282   PMID:34735949   PMID:34749751   PMID:34788473   PMID:34844091   PMID:34844236   PMID:34844996   PMID:34860473   PMID:34895107   PMID:34907862  
PMID:34915026   PMID:34931867   PMID:34954996   PMID:34963561   PMID:34988655   PMID:35008783   PMID:35068171   PMID:35093870   PMID:35162941   PMID:35235761   PMID:35235816   PMID:35256320  
PMID:35271311   PMID:35325436   PMID:35381649   PMID:35430998   PMID:35459184   PMID:35462331   PMID:35471238   PMID:35487881   PMID:35488449   PMID:35575683   PMID:35610207   PMID:35627114  
PMID:35654246   PMID:35727214   PMID:35810258   PMID:35815612   PMID:35853334   PMID:35883702   PMID:35887063   PMID:35960493   PMID:35968761   PMID:35970996   PMID:36071112   PMID:36087110  
PMID:36104708   PMID:36221036   PMID:36233042   PMID:36250837   PMID:36291159   PMID:36356904   PMID:36413758   PMID:36463535   PMID:36507589   PMID:36537755   PMID:36541130   PMID:36637703  
PMID:36681895   PMID:36688959   PMID:36698099   PMID:36720839   PMID:36724904   PMID:36749481   PMID:36833223   PMID:36931039   PMID:36973040   PMID:36983062   PMID:36988399   PMID:36999508  
PMID:37048130   PMID:37081725   PMID:37092084   PMID:37198710   PMID:37277970   PMID:37372371   PMID:37420302   PMID:37571901   PMID:37616343   PMID:37690777   PMID:37817654   PMID:37834286  
PMID:37875597   PMID:38226443   PMID:38270169   PMID:38270743   PMID:38272384   PMID:38287944   PMID:38297024   PMID:38409918   PMID:38426412   PMID:38665866   PMID:38809628   PMID:38920082  
PMID:38962329   PMID:39126083  


Genomics

Comparative Map Data
ABCB1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38787,503,017 - 87,713,295 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl787,503,017 - 87,713,323 (-)EnsemblGRCh38hg38GRCh38
GRCh37787,132,333 - 87,342,611 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36786,970,884 - 87,180,500 (-)NCBINCBI36Build 36hg18NCBI36
Build 34786,777,598 - 86,987,215NCBI
Celera781,837,832 - 82,047,176 (-)NCBICelera
Cytogenetic Map7q21.12NCBI
HuRef781,744,182 - 81,952,578 (-)NCBIHuRef
CHM1_1787,063,281 - 87,272,756 (-)NCBICHM1_1
T2T-CHM13v2.0788,752,787 - 88,963,178 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2786,464,691 - 86,673,953 (-)NCBI
Abcb1a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3958,617,091 - 8,798,575 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl58,710,077 - 8,798,575 (+)EnsemblGRCm39 Ensembl
GRCm3858,567,091 - 8,748,575 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl58,660,077 - 8,748,575 (+)EnsemblGRCm38mm10GRCm38
MGSCv3758,660,092 - 8,748,570 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3658,666,098 - 8,754,525 (+)NCBIMGSCv36mm8
Celera58,580,580 - 8,668,151 (+)NCBICelera
Cytogenetic Map5A1NCBI
cM Map53.43NCBI
Abcb1a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8426,312,403 - 26,488,456 (-)NCBIGRCr8
mRatBN7.2425,357,467 - 25,529,941 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl425,158,362 - 25,442,709 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx430,355,700 - 30,438,098 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0426,281,938 - 26,364,336 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0424,656,062 - 24,738,283 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0422,339,829 - 22,517,642 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl422,133,521 - 22,425,515 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0422,276,390 - 22,448,913 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4421,709,855 - 21,796,628 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1421,709,854 - 21,796,626 (+)NCBI
Celera420,849,575 - 20,934,573 (-)NCBICelera
Cytogenetic Map4q12NCBI
Abcb1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554324,911,774 - 5,085,349 (-)NCBIChiLan1.0ChiLan1.0
ABCB1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26105,382,570 - 105,590,973 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17153,647,208 - 153,855,840 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0779,497,536 - 79,706,277 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1793,147,217 - 93,355,231 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl793,147,950 - 93,243,238 (-)Ensemblpanpan1.1panPan2
ABCB1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11413,644,891 - 13,852,829 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1413,542,647 - 13,742,727 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1413,216,483 - 13,313,885 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01413,410,127 - 13,507,439 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1413,409,565 - 13,507,428 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11413,613,256 - 13,710,576 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01413,339,096 - 13,436,445 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01413,622,793 - 13,720,201 (-)NCBIUU_Cfam_GSD_1.0
Abcb1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511826,693,137 - 26,871,076 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367631,226,482 - 1,297,427 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367631,225,355 - 1,308,257 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ABCB1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1993,049,955 - 93,146,469 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29102,530,015 - 102,626,355 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ABCB1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12161,211,044 - 61,430,691 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2161,322,748 - 61,529,274 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604242,634,559 - 42,749,353 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

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Variants in ABCB1
703 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
ABCB1, ALA893SER/THR variation Inflammatory bowel disease 13 [RCV000014698]|Inflammatory bowel disease 13, susceptibility to [RCV000014698] Chr7:7q21.1 risk factor
ABCB1, 3435C-T single nucleotide variant MDR1 POLYMORPHISM [RCV000014699] Chr7:7q21.1 benign
NM_001348946.2(ABCB1):c.554G>T (p.Gly185Val) single nucleotide variant Colchicine resistance [RCV000014697] Chr7:87566218 [GRCh38]
Chr7:87195534 [GRCh37]
Chr7:7q21.12		 pathogenic
GRCh38/hg38 7p22.3-q36.3(chr7:53985-159282531)x1 copy number loss See cases [RCV000052250] Chr7:53985..159282531 [GRCh38]
Chr7:53985..159075220 [GRCh37]
Chr7:149068..158767981 [NCBI36]
Chr7:7p22.3-q36.3		 pathogenic
NM_000927.4(ABCB1):c.3240C>T (p.Val1080=) single nucleotide variant Malignant melanoma [RCV000067982] Chr7:87515273 [GRCh38]
Chr7:87144589 [GRCh37]
Chr7:86982525 [NCBI36]
Chr7:7q21.12		 not provided
NM_000927.4(ABCB1):c.2871C>T (p.Phe957=) single nucleotide variant Malignant melanoma [RCV000067983] Chr7:87519382 [GRCh38]
Chr7:87148698 [GRCh37]
Chr7:86986634 [NCBI36]
Chr7:7q21.12		 not provided
NM_000927.4(ABCB1):c.999+281G>T single nucleotide variant Lung cancer [RCV000106582] Chr7:87553480 [GRCh38]
Chr7:87182796 [GRCh37]
Chr7:7q21.12		 uncertain significance
NM_001134405.1(RUNDC3B):c.262G>A (p.Glu88Lys) single nucleotide variant Malignant melanoma [RCV000067984] Chr7:87700444 [GRCh38]
Chr7:87329760 [GRCh37]
Chr7:87167696 [NCBI36]
Chr7:7q21.12		 not provided
NM_001348946.2(ABCB1):c.1199G>A (p.Ser400Asn) single nucleotide variant ABCB1-related disorder [RCV003975269]|not provided [RCV004712153]|not specified [RCV000174262] Chr7:87550493 [GRCh38]
Chr7:87179809 [GRCh37]
Chr7:7q21.12		 benign|likely benign
NM_001348946.2(ABCB1):c.1236T>C (p.Gly412=) single nucleotide variant ABCB1-related disorder [RCV003975274]|Tramadol response [RCV001029394]|not provided [RCV000835734]|not specified [RCV000174498] Chr7:87550285 [GRCh38]
Chr7:87179601 [GRCh37]
Chr7:7q21.12		 benign|likely benign|drug response
NM_001134405.2(RUNDC3B):c.271C>T (p.Arg91Cys) single nucleotide variant not specified [RCV004268104] Chr7:87700453 [GRCh38]
Chr7:87329769 [GRCh37]
Chr7:7q21.12		 uncertain significance
NM_001134405.2(RUNDC3B):c.218T>G (p.Ile73Ser) single nucleotide variant not specified [RCV004273168] Chr7:87650917 [GRCh38]
Chr7:87280233 [GRCh37]
Chr7:7q21.12		 uncertain significance
NM_001348946.2(ABCB1):c.3435T>C (p.Ile1145=) single nucleotide variant ABCB1-related disorder [RCV003977583]|MDR1 POLYMORPHISM [RCV000014699]|Tramadol response [RCV001029504]|not provided [RCV000835732] Chr7:87509329 [GRCh38]
Chr7:87138645 [GRCh37]
Chr7:7q21.12		 benign|likely benign|drug response|not provided
GRCh38/hg38 7p22.3-q36.3(chr7:54185-159282390)x1 copy number loss See cases [RCV000135401] Chr7:54185..159282390 [GRCh38]
Chr7:54185..159075079 [GRCh37]
Chr7:149268..158767840 [NCBI36]
Chr7:7p22.3-q36.3		 pathogenic
GRCh38/hg38 7q21.12-21.2(chr7:87379476-91731873)x1 copy number loss See cases [RCV000139869] Chr7:87379476..91731873 [GRCh38]
Chr7:87008792..91361188 [GRCh37]
Chr7:86846728..91199124 [NCBI36]
Chr7:7q21.12-21.2		 likely pathogenic|uncertain significance
GRCh38/hg38 7q21.11-21.3(chr7:84002634-95228883)x1 copy number loss See cases [RCV000143271] Chr7:84002634..95228883 [GRCh38]
Chr7:83631950..94858195 [GRCh37]
Chr7:83469886..94696131 [NCBI36]
Chr7:7q21.11-21.3		 pathogenic
NM_001348946.2(ABCB1):c.2677T>A (p.Ser893Thr) single nucleotide variant ABCB1-related disorder [RCV003982909]|not provided [RCV004712142]|not specified [RCV000152713] Chr7:87531302 [GRCh38]
Chr7:87160618 [GRCh37]
Chr7:7q21.12		 benign|likely benign|not provided
NM_001348946.2(ABCB1):c.2677T>G (p.Ser893Ala) single nucleotide variant ABCB1-related disorder [RCV003975192]|Inflammatory bowel disease 13 [RCV000014698]|Tramadol response [RCV001028649]|not provided [RCV000835733]|not specified [RCV000152717] Chr7:87531302 [GRCh38]
Chr7:87160618 [GRCh37]
Chr7:7q21.12		 likely pathogenic|risk factor|benign|likely benign|drug response
GRCh37/hg19 7p22.3-q36.3(chr7:43360-159119707)x1 copy number loss See cases [RCV000446044] Chr7:43360..159119707 [GRCh37]
Chr7:7p22.3-q36.3		 pathogenic
NM_001348946.2(ABCB1):c.3435= (p.Ile1145=) single nucleotide variant not specified [RCV000602614] Chr7:87509329 [GRCh38]
Chr7:87138645 [GRCh37]
Chr7:7q21.12		 benign
TMEM106B-BRAF fusion deletion Pleomorphic xanthoastrocytoma [RCV000454357] Chr7:12258147..140494267 [GRCh37]
Chr7:7p21.3-q34		 pathogenic
GRCh37/hg19 7p22.3-q36.3(chr7:43361-159119707) copy number gain See cases [RCV000510686] Chr7:43361..159119707 [GRCh37]
Chr7:7p22.3-q36.3		 pathogenic
GRCh37/hg19 7p22.3-q36.3(chr7:43361-159119707)x3 copy number gain See cases [RCV000511549] Chr7:43361..159119707 [GRCh37]
Chr7:7p22.3-q36.3		 pathogenic
Single allele deletion not provided [RCV000677988] Chr7:73591993..93683437 [GRCh37]
Chr7:7q11.23-21.3		 uncertain significance
NC_000007.13:g.(20954043_21001537)_(114528369_114556605)inv inversion Childhood apraxia of speech [RCV000234948] Chr7:21001537..114528369 [GRCh37]
Chr7:7p15.3-q31.1		 pathogenic
GRCh37/hg19 7p22.3-q36.3(chr7:10704-159122532)x3 copy number gain not provided [RCV000746278] Chr7:10704..159122532 [GRCh37]
Chr7:7p22.3-q36.3		 pathogenic
GRCh37/hg19 7p22.3-q36.3(chr7:44935-159126310)x3 copy number gain not provided [RCV000746280] Chr7:44935..159126310 [GRCh37]
Chr7:7p22.3-q36.3		 pathogenic
GRCh37/hg19 7q21.12(chr7:87234049-87564277)x1 copy number loss not provided [RCV000746867] Chr7:87234049..87564277 [GRCh37]
Chr7:7q21.12		 benign
GRCh37/hg19 7q21.12(chr7:87236013-87251641)x1 copy number loss not provided [RCV000746868] Chr7:87236013..87251641 [GRCh37]
Chr7:7q21.12		 benign
GRCh37/hg19 7q21.12(chr7:87278027-87279531)x1 copy number loss not provided [RCV000746869] Chr7:87278027..87279531 [GRCh37]
Chr7:7q21.12		 benign
GRCh37/hg19 7q21.12(chr7:87278027-87279856)x1 copy number loss not provided [RCV000746870] Chr7:87278027..87279856 [GRCh37]
Chr7:7q21.12		 benign
GRCh37/hg19 7q21.12(chr7:87317396-87346819)x3 copy number gain not provided [RCV000746871] Chr7:87317396..87346819 [GRCh37]
Chr7:7q21.12		 benign
GRCh37/hg19 7q21.12(chr7:87317396-87370183)x3 copy number gain not provided [RCV000746872] Chr7:87317396..87370183 [GRCh37]
Chr7:7q21.12		 benign
NM_001348946.2(ABCB1):c.1149C>T (p.His383=) single nucleotide variant not provided [RCV000885191] Chr7:87550543 [GRCh38]
Chr7:87179859 [GRCh37]
Chr7:7q21.12		 likely benign
NM_001348946.2(ABCB1):c.1662G>C (p.Leu554=) single nucleotide variant not provided [RCV000904359] Chr7:87549411 [GRCh38]
Chr7:87178727 [GRCh37]
Chr7:7q21.12		 benign
NM_001348946.2(ABCB1):c.1854G>A (p.Glu618=) single nucleotide variant not provided [RCV000915709] Chr7:87545896 [GRCh38]
Chr7:87175212 [GRCh37]
Chr7:7q21.12		 likely benign
NM_001348946.2(ABCB1):c.3320A>C (p.Gln1107Pro) single nucleotide variant Tramadol response [RCV001029497]|not provided [RCV000903000] Chr7:87509444 [GRCh38]
Chr7:87138760 [GRCh37]
Chr7:7q21.12		 benign|conflicting interpretations of pathogenicity|drug response
NM_001348946.2(ABCB1):c.3747C>G (p.Gly1249=) single nucleotide variant ABCB1-related disorder [RCV003933122]|not provided [RCV000923707] Chr7:87504339 [GRCh38]
Chr7:87133655 [GRCh37]
Chr7:7q21.12		 likely benign
NM_001348946.2(ABCB1):c.1799G>A (p.Gly600Asp) single nucleotide variant not specified [RCV004308937] Chr7:87545951 [GRCh38]
Chr7:87175267 [GRCh37]
Chr7:7q21.12		 uncertain significance
NM_001348946.2(ABCB1):c.548A>G (p.Asn183Ser) single nucleotide variant not provided [RCV000879421] Chr7:87566224 [GRCh38]
Chr7:87195540 [GRCh37]
Chr7:7q21.12		 benign
NM_001348946.2(ABCB1):c.1225-4G>A single nucleotide variant not provided [RCV000904360] Chr7:87550300 [GRCh38]
Chr7:87179616 [GRCh37]
Chr7:7q21.12		 benign
NM_001348946.2(ABCB1):c.729A>G (p.Glu243=) single nucleotide variant not provided [RCV000892271] Chr7:87561361 [GRCh38]
Chr7:87190677 [GRCh37]
Chr7:7q21.12		 benign|likely benign
NM_001348946.2(ABCB1):c.2679T>C (p.Ser893=) single nucleotide variant not provided [RCV000925667] Chr7:87531300 [GRCh38]
Chr7:87160616 [GRCh37]
Chr7:7q21.12		 likely benign
NM_001348946.2(ABCB1):c.3396C>T (p.Ala1132=) single nucleotide variant ABCB1-related disorder [RCV003960746]|not provided [RCV000963217] Chr7:87509368 [GRCh38]
Chr7:87138684 [GRCh37]
Chr7:7q21.12		 benign|likely benign
NM_001348946.2(ABCB1):c.1000-8T>A single nucleotide variant not provided [RCV000943076] Chr7:87550846 [GRCh38]
Chr7:87180162 [GRCh37]
Chr7:7q21.12		 likely benign
NM_001348946.2(ABCB1):c.2106G>A (p.Lys702=) single nucleotide variant ABCB1-related disorder [RCV003960490]|not provided [RCV000931993] Chr7:87544234 [GRCh38]
Chr7:87173550 [GRCh37]
Chr7:7q21.12		 likely benign
NM_001348946.2(ABCB1):c.1794C>T (p.Ile598=) single nucleotide variant ABCB1-related disorder [RCV004758095]|not provided [RCV000924107] Chr7:87545956 [GRCh38]
Chr7:87175272 [GRCh37]
Chr7:7q21.12		 likely benign
GRCh37/hg19 7p22.3-q36.3(chr7:10365-159119707)x3 copy number gain not provided [RCV000848126] Chr7:10365..159119707 [GRCh37]
Chr7:7p22.3-q36.3		 pathogenic
NM_001348946.2(ABCB1):c.287-25G>T single nucleotide variant Tramadol response [RCV001029311]|not provided [RCV000835175] Chr7:87570248 [GRCh38]
Chr7:87199564 [GRCh37]
Chr7:7q21.12		 benign|drug response
NM_001348946.2(ABCB1):c.200_201del (p.Leu67fs) microsatellite Tramadol response [RCV001029293] Chr7:87585597..87585598 [GRCh38]
Chr7:87214913..87214914 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.267G>A (p.Met89Ile) single nucleotide variant Tramadol response [RCV001029297] Chr7:87585531 [GRCh38]
Chr7:87214847 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.287-101T>C single nucleotide variant Tramadol response [RCV001029309] Chr7:87570324 [GRCh38]
Chr7:87199640 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.339-275C>T single nucleotide variant Tramadol response [RCV001029332] Chr7:87567251 [GRCh38]
Chr7:87196567 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.350A>T (p.Tyr117Phe) single nucleotide variant Tramadol response [RCV001029335] Chr7:87566965 [GRCh38]
Chr7:87196281 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.531-27T>C single nucleotide variant Tramadol response [RCV001029340] Chr7:87566268 [GRCh38]
Chr7:87195584 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.600T>G (p.Phe200Leu) single nucleotide variant Tramadol response [RCV001029342] Chr7:87566172 [GRCh38]
Chr7:87195488 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.702+280G>A single nucleotide variant Tramadol response [RCV001029350] Chr7:87565790 [GRCh38]
Chr7:87195106 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.827+44C>G single nucleotide variant Tramadol response [RCV001029353] Chr7:87561219 [GRCh38]
Chr7:87190535 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.827+49C>T single nucleotide variant Tramadol response [RCV001029354] Chr7:87561214 [GRCh38]
Chr7:87190530 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1208C>G (p.Ser403Cys) single nucleotide variant Tramadol response [RCV001029385] Chr7:87550484 [GRCh38]
Chr7:87179800 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1379C>A (p.Thr460Asn) single nucleotide variant Tramadol response [RCV001029402] Chr7:87550026 [GRCh38]
Chr7:87179342 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1554+58C>G single nucleotide variant Tramadol response [RCV001029406] Chr7:87549793 [GRCh38]
Chr7:87179109 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1554+120A>T single nucleotide variant Tramadol response [RCV001029410] Chr7:87549731 [GRCh38]
Chr7:87179047 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1726-582T>G single nucleotide variant Tramadol response [RCV001029417] Chr7:87546606 [GRCh38]
Chr7:87175922 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1726-577A>C single nucleotide variant Tramadol response [RCV001029418] Chr7:87546601 [GRCh38]
Chr7:87175917 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1726-104G>A single nucleotide variant Tramadol response [RCV001029419] Chr7:87546128 [GRCh38]
Chr7:87175444 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1887+30T>C single nucleotide variant Tramadol response [RCV001029425] Chr7:87545833 [GRCh38]
Chr7:87175149 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1887+32A>G single nucleotide variant Tramadol response [RCV001029426] Chr7:87545831 [GRCh38]
Chr7:87175147 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.2065-76T>A single nucleotide variant Tramadol response [RCV001029432] Chr7:87544351 [GRCh38]
Chr7:87173667 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.2211+25A>C single nucleotide variant Tramadol response [RCV001029446] Chr7:87544104 [GRCh38]
Chr7:87173420 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.2481+14T>A single nucleotide variant Tramadol response [RCV001029470] Chr7:87536444 [GRCh38]
Chr7:87165760 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.2481+28G>T single nucleotide variant Tramadol response [RCV001029471] Chr7:87536430 [GRCh38]
Chr7:87165746 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.2927+34A>G single nucleotide variant Tramadol response [RCV001029480] Chr7:87519292 [GRCh38]
Chr7:87148608 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.3282+32G>T single nucleotide variant Tramadol response [RCV001029490] Chr7:87515199 [GRCh38]
Chr7:87144515 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.3283-50C>T single nucleotide variant Tramadol response [RCV001029494] Chr7:87509531 [GRCh38]
Chr7:87138847 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.*420C>G single nucleotide variant Tramadol response [RCV001029529] Chr7:87503823 [GRCh38]
Chr7:87133139 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.*424C>T single nucleotide variant Tramadol response [RCV001029531] Chr7:87503819 [GRCh38]
Chr7:87133135 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.2781A>G (p.Pro927=) single nucleotide variant not provided [RCV000942572] Chr7:87520781 [GRCh38]
Chr7:87150097 [GRCh37]
Chr7:7q21.12		 likely benign
NM_001348946.2(ABCB1):c.2650C>T (p.Leu884=) single nucleotide variant not provided [RCV000963218]|not specified [RCV004029905] Chr7:87531329 [GRCh38]
Chr7:87160645 [GRCh37]
Chr7:7q21.12		 benign|likely benign
NM_001348946.2(ABCB1):c.101T>G (p.Val34Gly) single nucleotide variant Tramadol response [RCV001028459] Chr7:87595782 [GRCh38]
Chr7:87225098 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.118-12CT[2] microsatellite Tramadol response [RCV001028484] Chr7:87585687..87585688 [GRCh38]
Chr7:87215003..87215004 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.128C>T (p.Ser43Leu) single nucleotide variant Tramadol response [RCV001028487] Chr7:87585670 [GRCh38]
Chr7:87214986 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.702+348T>G single nucleotide variant Tramadol response [RCV001028534] Chr7:87565722 [GRCh38]
Chr7:87195038 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.828-363G>T single nucleotide variant Tramadol response [RCV001028557] Chr7:87554295 [GRCh38]
Chr7:87183611 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.828-359T>G single nucleotide variant Tramadol response [RCV001028558] Chr7:87554291 [GRCh38]
Chr7:87183607 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1038A>C (p.Gly346=) single nucleotide variant Tramadol response [RCV001028569] Chr7:87550800 [GRCh38]
Chr7:87180116 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1067C>T (p.Ala356Val) single nucleotide variant Tramadol response [RCV001028571] Chr7:87550771 [GRCh38]
Chr7:87180087 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1113+40T>C single nucleotide variant Tramadol response [RCV001028574] Chr7:87550685 [GRCh38]
Chr7:87180001 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1113+66C>A single nucleotide variant Tramadol response [RCV001028576] Chr7:87550659 [GRCh38]
Chr7:87179975 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1305A>G (p.Thr435=) single nucleotide variant Tramadol response [RCV001028586] Chr7:87550216 [GRCh38]
Chr7:87179532 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1320G>A (p.Met440Ile) single nucleotide variant Tramadol response [RCV001028587]|not specified [RCV004030901] Chr7:87550201 [GRCh38]
Chr7:87179517 [GRCh37]
Chr7:7q21.12		 drug response|uncertain significance
NM_001348946.2(ABCB1):c.1570G>A (p.Val524Ile) single nucleotide variant Tramadol response [RCV001028601] Chr7:87549503 [GRCh38]
Chr7:87178819 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1624G>A (p.Ala542Thr) single nucleotide variant Tramadol response [RCV001028604] Chr7:87549449 [GRCh38]
Chr7:87178765 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1628G>A (p.Arg543His) single nucleotide variant Tramadol response [RCV001028605] Chr7:87549445 [GRCh38]
Chr7:87178761 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1711G>A (p.Val571Met) single nucleotide variant Tramadol response [RCV001028606] Chr7:87549362 [GRCh38]
Chr7:87178678 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1725+38G>A single nucleotide variant Tramadol response [RCV001028608] Chr7:87549310 [GRCh38]
Chr7:87178626 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1725+157T>C single nucleotide variant Tramadol response [RCV001028612] Chr7:87549191 [GRCh38]
Chr7:87178507 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.2064+30A>T single nucleotide variant Tramadol response [RCV001028621] Chr7:87544793 [GRCh38]
Chr7:87174109 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.2064+84G>T single nucleotide variant Tramadol response [RCV001028623] Chr7:87544739 [GRCh38]
Chr7:87174055 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.2212-38C>T single nucleotide variant Tramadol response [RCV001028636] Chr7:87541502 [GRCh38]
Chr7:87170818 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.2240C>T (p.Thr747Ile) single nucleotide variant Tramadol response [RCV001028640] Chr7:87541436 [GRCh38]
Chr7:87170752 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.2319+1G>T single nucleotide variant Tramadol response [RCV001028642] Chr7:87541356 [GRCh38]
Chr7:87170672 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.3489+5G>A single nucleotide variant Tramadol response [RCV001028676] Chr7:87509270 [GRCh38]
Chr7:87138586 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.3489+18T>C single nucleotide variant Tramadol response [RCV001028677] Chr7:87509257 [GRCh38]
Chr7:87138573 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.*34del deletion Tramadol response [RCV001028693] Chr7:87504209 [GRCh38]
Chr7:87133525 [GRCh37]
Chr7:7q21.12		 drug response
NC_000007.14:g.87713394C>T single nucleotide variant Tramadol response [RCV001029213] Chr7:87713394 [GRCh38]
Chr7:87342710 [GRCh37]
Chr7:7q21.12		 drug response
NM_000927.5(ABCB1):c.-208G>A single nucleotide variant Tramadol response [RCV001029231] Chr7:87600956 [GRCh38]
Chr7:87230272 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.69-24T>G single nucleotide variant Tramadol response [RCV001029268] Chr7:87595838 [GRCh38]
Chr7:87225154 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.117+188A>T single nucleotide variant Tramadol response [RCV001029279] Chr7:87595578 [GRCh38]
Chr7:87224894 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.-7+156C>T single nucleotide variant Tramadol response [RCV001028431] Chr7:87600599 [GRCh38]
Chr7:87229915 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.68+428T>A single nucleotide variant Tramadol response [RCV001028445] Chr7:87599689 [GRCh38]
Chr7:87229005 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.68+431A>T single nucleotide variant Tramadol response [RCV001028447] Chr7:87599686 [GRCh38]
Chr7:87229002 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.68+432A>C single nucleotide variant Tramadol response [RCV001028448] Chr7:87599685 [GRCh38]
Chr7:87229001 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.99T>A (p.Thr33=) single nucleotide variant Tramadol response [RCV001028458] Chr7:87595784 [GRCh38]
Chr7:87225100 [GRCh37]
Chr7:7q21.12		 drug response
NM_000927.5(ABCB1):c.-428A>G single nucleotide variant Tramadol response [RCV001029220] Chr7:87713258 [GRCh38]
Chr7:87342574 [GRCh37]
Chr7:7q21.12		 drug response
NM_000927.5(ABCB1):c.-361G>C single nucleotide variant Tramadol response [RCV001029224] Chr7:87713191 [GRCh38]
Chr7:87342507 [GRCh37]
Chr7:7q21.12		 drug response
NM_000927.5(ABCB1):c.-256C>T single nucleotide variant Tramadol response [RCV001029226] Chr7:87601004 [GRCh38]
Chr7:87230320 [GRCh37]
Chr7:7q21.12		 drug response
NM_000927.5(ABCB1):c.-173G>A single nucleotide variant Tramadol response [RCV001029235] Chr7:87600921 [GRCh38]
Chr7:87230237 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.68+18T>G single nucleotide variant Tramadol response [RCV001029250] Chr7:87600099 [GRCh38]
Chr7:87229415 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.68+25A>G single nucleotide variant Tramadol response [RCV001029251] Chr7:87600092 [GRCh38]
Chr7:87229408 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.68+28T>C single nucleotide variant Tramadol response [RCV001029252] Chr7:87600089 [GRCh38]
Chr7:87229405 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.68+37T>A single nucleotide variant Tramadol response [RCV001029254] Chr7:87600080 [GRCh38]
Chr7:87229396 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.69-28T>G single nucleotide variant Tramadol response [RCV001029266] Chr7:87595842 [GRCh38]
Chr7:87225158 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.286+677T>G single nucleotide variant Tramadol response [RCV001029305] Chr7:87584835 [GRCh38]
Chr7:87214151 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.286+683T>G single nucleotide variant Tramadol response [RCV001029307] Chr7:87584829 [GRCh38]
Chr7:87214145 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.322G>T (p.Glu108Ter) single nucleotide variant Tramadol response [RCV001029313] Chr7:87570188 [GRCh38]
Chr7:87199504 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.339-4del deletion Tramadol response [RCV001029334] Chr7:87566980 [GRCh38]
Chr7:87196296 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.530+270C>T single nucleotide variant Tramadol response [RCV001029336] Chr7:87566515 [GRCh38]
Chr7:87195831 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.607G>A (p.Gly203Arg) single nucleotide variant Tramadol response [RCV001029343] Chr7:87566165 [GRCh38]
Chr7:87195481 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.632G>A (p.Gly211Asp) single nucleotide variant Tramadol response [RCV001029344] Chr7:87566140 [GRCh38]
Chr7:87195456 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.828-736A>G single nucleotide variant Tramadol response [RCV001029366] Chr7:87554668 [GRCh38]
Chr7:87183984 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.908T>A (p.Phe303Tyr) single nucleotide variant Tramadol response [RCV001029371] Chr7:87553852 [GRCh38]
Chr7:87183168 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.960G>A (p.Leu320=) single nucleotide variant Tramadol response [RCV001029372] Chr7:87553800 [GRCh38]
Chr7:87183116 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.999+37A>G single nucleotide variant Tramadol response [RCV001029375] Chr7:87553724 [GRCh38]
Chr7:87183040 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1000-108C>G single nucleotide variant Tramadol response [RCV001029377] Chr7:87550946 [GRCh38]
Chr7:87180262 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1360G>A (p.Asp454Asn) single nucleotide variant Tramadol response [RCV001029401] Chr7:87550045 [GRCh38]
Chr7:87179361 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1726-96del deletion Tramadol response [RCV001029420] Chr7:87546120 [GRCh38]
Chr7:87175436 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1887+28A>G single nucleotide variant Tramadol response [RCV001029424] Chr7:87545835 [GRCh38]
Chr7:87175151 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1888-93del deletion Tramadol response [RCV001029428] Chr7:87545092 [GRCh38]
Chr7:87174408 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.2366G>A (p.Arg789Gln) single nucleotide variant Tramadol response [RCV001029455] Chr7:87539299 [GRCh38]
Chr7:87168615 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.2532G>T (p.Gly844=) single nucleotide variant Tramadol response [RCV001029472] Chr7:87531447 [GRCh38]
Chr7:87160763 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.3084+27T>G single nucleotide variant Tramadol response [RCV001029485] Chr7:87516482 [GRCh38]
Chr7:87145798 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.3084+28C>T single nucleotide variant Tramadol response [RCV001029486] Chr7:87516481 [GRCh38]
Chr7:87145797 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.3283-37C>T single nucleotide variant Tramadol response [RCV001029495] Chr7:87509518 [GRCh38]
Chr7:87138834 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.3355G>A (p.Glu1119Lys) single nucleotide variant Tramadol response [RCV001029500] Chr7:87509409 [GRCh38]
Chr7:87138725 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.3637-11T>G single nucleotide variant Tramadol response [RCV001029505] Chr7:87504460 [GRCh38]
Chr7:87133776 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.3679T>A (p.Cys1227Ser) single nucleotide variant Tramadol response [RCV001029509] Chr7:87504407 [GRCh38]
Chr7:87133723 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.3837C>T (p.Arg1279=) single nucleotide variant Tramadol response [RCV001029518] Chr7:87504249 [GRCh38]
Chr7:87133565 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.*298C>T single nucleotide variant Tramadol response [RCV001029525] Chr7:87503945 [GRCh38]
Chr7:87133261 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.*394G>A single nucleotide variant Tramadol response [RCV001029528] Chr7:87503849 [GRCh38]
Chr7:87133165 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.2925G>A (p.Leu975=) single nucleotide variant not provided [RCV000914168] Chr7:87519328 [GRCh38]
Chr7:87148644 [GRCh37]
Chr7:7q21.12		 likely benign
NM_001348946.2(ABCB1):c.-7+41C>T single nucleotide variant Tramadol response [RCV001028428] Chr7:87600714 [GRCh38]
Chr7:87230030 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.-7+158A>G single nucleotide variant Tramadol response [RCV001028433] Chr7:87600597 [GRCh38]
Chr7:87229913 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.-7+167A>G single nucleotide variant Tramadol response [RCV001028436] Chr7:87600588 [GRCh38]
Chr7:87229904 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.69-780C>T single nucleotide variant Tramadol response [RCV001028452] Chr7:87596594 [GRCh38]
Chr7:87225910 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.117+134G>C single nucleotide variant Tramadol response [RCV001028466] Chr7:87595632 [GRCh38]
Chr7:87224948 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.286+305G>A single nucleotide variant Tramadol response [RCV001028490] Chr7:87585207 [GRCh38]
Chr7:87214523 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.338+185G>T single nucleotide variant Tramadol response [RCV001028505] Chr7:87569987 [GRCh38]
Chr7:87199303 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.338+337C>T single nucleotide variant Tramadol response [RCV001028517] Chr7:87569835 [GRCh38]
Chr7:87199151 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.368C>T (p.Ala123Val) single nucleotide variant Tramadol response [RCV001028518] Chr7:87566947 [GRCh38]
Chr7:87196263 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.468G>A (p.Met156Ile) single nucleotide variant Tramadol response [RCV001028520] Chr7:87566847 [GRCh38]
Chr7:87196163 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.527del (p.Thr176fs) deletion Tramadol response [RCV001028526] Chr7:87566788 [GRCh38]
Chr7:87196104 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.530+32G>A single nucleotide variant Tramadol response [RCV001028528] Chr7:87566753 [GRCh38]
Chr7:87196069 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.530+35G>A single nucleotide variant Tramadol response [RCV001028529] Chr7:87566750 [GRCh38]
Chr7:87196066 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.703-966G>C single nucleotide variant Tramadol response [RCV001028541] Chr7:87562353 [GRCh38]
Chr7:87191669 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1113+17C>T single nucleotide variant Tramadol response [RCV001028572] Chr7:87550708 [GRCh38]
Chr7:87180024 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1113+71del deletion Tramadol response [RCV001028577] Chr7:87550654 [GRCh38]
Chr7:87179970 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1297A>G (p.Lys433Glu) single nucleotide variant Tramadol response [RCV001028582] Chr7:87550224 [GRCh38]
Chr7:87179540 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1350+40C>T single nucleotide variant Tramadol response [RCV001028595] Chr7:87550131 [GRCh38]
Chr7:87179447 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1555-61T>A single nucleotide variant Tramadol response [RCV001028598] Chr7:87549579 [GRCh38]
Chr7:87178895 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1969G>A (p.Asp657Asn) single nucleotide variant Tramadol response [RCV001028615] Chr7:87544918 [GRCh38]
Chr7:87174234 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.2065-97G>A single nucleotide variant Tramadol response [RCV001028625] Chr7:87544372 [GRCh38]
Chr7:87173688 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.2065-92G>T single nucleotide variant Tramadol response [RCV001028626] Chr7:87544367 [GRCh38]
Chr7:87173683 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.2319+35G>T single nucleotide variant Tramadol response [RCV001028643] Chr7:87541322 [GRCh38]
Chr7:87170638 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.3207G>C (p.Val1069=) single nucleotide variant Tramadol response [RCV001028670] Chr7:87515306 [GRCh38]
Chr7:87144622 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.3571G>A (p.Val1191Ile) single nucleotide variant Tramadol response [RCV001028688] Chr7:87505962 [GRCh38]
Chr7:87135278 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.*89A>T single nucleotide variant Tramadol response [RCV001028697] Chr7:87504154 [GRCh38]
Chr7:87133470 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.*154A>G single nucleotide variant Tramadol response [RCV001028699] Chr7:87504089 [GRCh38]
Chr7:87133405 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.*179A>C single nucleotide variant Tramadol response [RCV001028703] Chr7:87504064 [GRCh38]
Chr7:87133380 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.*183G>T single nucleotide variant Tramadol response [RCV001028704] Chr7:87504060 [GRCh38]
Chr7:87133376 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.*183del deletion Tramadol response [RCV001028705] Chr7:87504060 [GRCh38]
Chr7:87133376 [GRCh37]
Chr7:7q21.12		 drug response
NM_000927.5(ABCB1):c.-331+80T>G single nucleotide variant Tramadol response [RCV001028411] Chr7:87713081 [GRCh38]
Chr7:87342397 [GRCh37]
Chr7:7q21.12		 drug response
NM_000927.5(ABCB1):c.-331+81G>A single nucleotide variant Tramadol response [RCV001028412] Chr7:87713080 [GRCh38]
Chr7:87342396 [GRCh37]
Chr7:7q21.12		 drug response
NM_000927.5(ABCB1):c.-267G>T single nucleotide variant Tramadol response [RCV001028422] Chr7:87601015 [GRCh38]
Chr7:87230331 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.-7+139A>G single nucleotide variant Tramadol response [RCV001028430] Chr7:87600616 [GRCh38]
Chr7:87229932 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.-7+159G>A single nucleotide variant Tramadol response [RCV001028434] Chr7:87600596 [GRCh38]
Chr7:87229912 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.68+408G>A single nucleotide variant Tramadol response [RCV001028442] Chr7:87599709 [GRCh38]
Chr7:87229025 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.69-777A>G single nucleotide variant Tramadol response [RCV001028455] Chr7:87596591 [GRCh38]
Chr7:87225907 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.117+153A>G single nucleotide variant Tramadol response [RCV001028468] Chr7:87595613 [GRCh38]
Chr7:87224929 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.117+155A>G single nucleotide variant Tramadol response [RCV001028470] Chr7:87595611 [GRCh38]
Chr7:87224927 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.118-25G>A single nucleotide variant Tramadol response [RCV001028481] Chr7:87585705 [GRCh38]
Chr7:87215021 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.118-10del deletion Tramadol response [RCV001028482] Chr7:87585690 [GRCh38]
Chr7:87215006 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.118-9del deletion Tramadol response [RCV001028483] Chr7:87585689 [GRCh38]
Chr7:87215005 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.475del (p.Glu159fs) deletion Tramadol response [RCV001028521] Chr7:87566840 [GRCh38]
Chr7:87196156 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.530+30G>T single nucleotide variant Tramadol response [RCV001028527] Chr7:87566755 [GRCh38]
Chr7:87196071 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.530+139C>T single nucleotide variant Tramadol response [RCV001028531] Chr7:87566646 [GRCh38]
Chr7:87195962 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.702+390A>C single nucleotide variant Tramadol response [RCV001028537] Chr7:87565680 [GRCh38]
Chr7:87194996 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.703-1034G>T single nucleotide variant Tramadol response [RCV001028540] Chr7:87562421 [GRCh38]
Chr7:87191737 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.703-946A>G single nucleotide variant Tramadol response [RCV001028544] Chr7:87562333 [GRCh38]
Chr7:87191649 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.828-608C>A single nucleotide variant Tramadol response [RCV001028554] Chr7:87554540 [GRCh38]
Chr7:87183856 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.828-509T>C single nucleotide variant Tramadol response [RCV001028556] Chr7:87554441 [GRCh38]
Chr7:87183757 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1121G>A (p.Ser374Asn) single nucleotide variant Tramadol response [RCV001028579] Chr7:87550571 [GRCh38]
Chr7:87179887 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1295G>T (p.Gly432Val) single nucleotide variant Tramadol response [RCV001028581] Chr7:87550226 [GRCh38]
Chr7:87179542 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1325G>C (p.Arg442Thr) single nucleotide variant Tramadol response [RCV001028588] Chr7:87550196 [GRCh38]
Chr7:87179512 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1350+30C>T single nucleotide variant Tramadol response [RCV001028592] Chr7:87550141 [GRCh38]
Chr7:87179457 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.2211+30C>T single nucleotide variant Tramadol response [RCV001028629] Chr7:87544099 [GRCh38]
Chr7:87173415 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.2212-128C>T single nucleotide variant Tramadol response [RCV001028631] Chr7:87541592 [GRCh38]
Chr7:87170908 [GRCh37]
Chr7:7q21.12		 drug response
NM_000927.5(ABCB1):c.-287C>T single nucleotide variant Tramadol response [RCV001028418] Chr7:87601035 [GRCh38]
Chr7:87230351 [GRCh37]
Chr7:7q21.12		 drug response
NM_000927.5(ABCB1):c.-271C>T single nucleotide variant Tramadol response [RCV001028421] Chr7:87601019 [GRCh38]
Chr7:87230335 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.-80T>G single nucleotide variant Tramadol response [RCV001028424] Chr7:87600828 [GRCh38]
Chr7:87230144 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.-7+12C>T single nucleotide variant Tramadol response [RCV001028427] Chr7:87600743 [GRCh38]
Chr7:87230059 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.68+407T>A single nucleotide variant Tramadol response [RCV001028441] Chr7:87599710 [GRCh38]
Chr7:87229026 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.68+427A>C single nucleotide variant Tramadol response [RCV001028444] Chr7:87599690 [GRCh38]
Chr7:87229006 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.69-908G>C single nucleotide variant Tramadol response [RCV001028450] Chr7:87596722 [GRCh38]
Chr7:87226038 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.94C>A (p.Pro32Thr) single nucleotide variant Tramadol response [RCV001028456] Chr7:87595789 [GRCh38]
Chr7:87225105 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.286+327A>G single nucleotide variant Tramadol response [RCV001028494] Chr7:87585185 [GRCh38]
Chr7:87214501 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.338+306C>T single nucleotide variant Tramadol response [RCV001028510] Chr7:87569866 [GRCh38]
Chr7:87199182 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.338+308A>C single nucleotide variant Tramadol response [RCV001028511] Chr7:87569864 [GRCh38]
Chr7:87199180 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.493G>A (p.Val165Met) single nucleotide variant Tramadol response [RCV001028522] Chr7:87566822 [GRCh38]
Chr7:87196138 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.2786+22G>T single nucleotide variant Tramadol response [RCV001028656] Chr7:87520754 [GRCh38]
Chr7:87150070 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.2787-70C>T single nucleotide variant Tramadol response [RCV001028658] Chr7:87519536 [GRCh38]
Chr7:87148852 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.3085-45T>C single nucleotide variant Tramadol response [RCV001028661] Chr7:87515473 [GRCh38]
Chr7:87144789 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.3143C>T (p.Pro1048Leu) single nucleotide variant Tramadol response [RCV001028664] Chr7:87515370 [GRCh38]
Chr7:87144686 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.3187G>T (p.Gly1063Cys) single nucleotide variant Tramadol response [RCV001028667] Chr7:87515326 [GRCh38]
Chr7:87144642 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.3224G>A (p.Gly1075Glu) single nucleotide variant Tramadol response [RCV001028671] Chr7:87515289 [GRCh38]
Chr7:87144605 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.3490-84A>C single nucleotide variant Tramadol response [RCV001028678] Chr7:87506127 [GRCh38]
Chr7:87135443 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.3543A>C (p.Lys1181Asn) single nucleotide variant Tramadol response [RCV001028684] Chr7:87505990 [GRCh38]
Chr7:87135306 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.3601G>A (p.Glu1201Lys) single nucleotide variant Tramadol response [RCV001028689] Chr7:87505932 [GRCh38]
Chr7:87135248 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.3636+30T>C single nucleotide variant Tramadol response [RCV001028690] Chr7:87505867 [GRCh38]
Chr7:87135183 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.*28T>G single nucleotide variant Tramadol response [RCV001028692] Chr7:87504215 [GRCh38]
Chr7:87133531 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.*63A>C single nucleotide variant Tramadol response [RCV001028694] Chr7:87504180 [GRCh38]
Chr7:87133496 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.828-615T>C single nucleotide variant Tramadol response [RCV001028553] Chr7:87554547 [GRCh38]
Chr7:87183863 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.828-106A>G single nucleotide variant Tramadol response [RCV001028562] Chr7:87554038 [GRCh38]
Chr7:87183354 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.828-87A>C single nucleotide variant Tramadol response [RCV001028563] Chr7:87554019 [GRCh38]
Chr7:87183335 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1350+39G>A single nucleotide variant Tramadol response [RCV001028594] Chr7:87550132 [GRCh38]
Chr7:87179448 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.2058G>A (p.Glu686=) single nucleotide variant Tramadol response [RCV001028617] Chr7:87544829 [GRCh38]
Chr7:87174145 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.2212-76C>T single nucleotide variant Tramadol response [RCV001028634] Chr7:87541540 [GRCh38]
Chr7:87170856 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.2620G>A (p.Val874Ile) single nucleotide variant Tramadol response [RCV001028645] Chr7:87531359 [GRCh38]
Chr7:87160675 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.2627T>G (p.Met876Arg) single nucleotide variant Tramadol response [RCV001028646] Chr7:87531352 [GRCh38]
Chr7:87160668 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.2686-10T>A single nucleotide variant Tramadol response [RCV001028654] Chr7:87520886 [GRCh38]
Chr7:87150202 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.2786+30T>C single nucleotide variant Tramadol response [RCV001028657] Chr7:87520746 [GRCh38]
Chr7:87150062 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.3085-9T>G single nucleotide variant Tramadol response [RCV001028662] Chr7:87515437 [GRCh38]
Chr7:87144753 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.3195G>A (p.Thr1065=) single nucleotide variant Tramadol response [RCV001028668] Chr7:87515318 [GRCh38]
Chr7:87144634 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.3282+2T>G single nucleotide variant Tramadol response [RCV001028675] Chr7:87515229 [GRCh38]
Chr7:87144545 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.3490-11C>T single nucleotide variant Tramadol response [RCV001028680] Chr7:87506054 [GRCh38]
Chr7:87135370 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.3501T>A (p.Thr1167=) single nucleotide variant Tramadol response [RCV001028681] Chr7:87506032 [GRCh38]
Chr7:87135348 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.*174C>T single nucleotide variant Tramadol response [RCV001028702] Chr7:87504069 [GRCh38]
Chr7:87133385 [GRCh37]
Chr7:7q21.12		 drug response
NC_000007.14:g.87713318G>A single nucleotide variant Tramadol response [RCV001029218] Chr7:87713318 [GRCh38]
Chr7:87342634 [GRCh37]
Chr7:7q21.12		 drug response
NM_000927.5(ABCB1):c.-210C>T single nucleotide variant Tramadol response [RCV001029230] Chr7:87600958 [GRCh38]
Chr7:87230274 [GRCh37]
Chr7:7q21.12		 drug response
NM_000927.5(ABCB1):c.-193C>A single nucleotide variant Tramadol response [RCV001029233] Chr7:87600941 [GRCh38]
Chr7:87230257 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.-88G>A single nucleotide variant Tramadol response [RCV001029241] Chr7:87600836 [GRCh38]
Chr7:87230152 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.-6-19A>C single nucleotide variant Tramadol response [RCV001029246] Chr7:87600209 [GRCh38]
Chr7:87229525 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.-1A>G single nucleotide variant Tramadol response [RCV001029247] Chr7:87600185 [GRCh38]
Chr7:87229501 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.61A>G (p.Asn21Asp) single nucleotide variant ABCB1-related disorder [RCV003973031]|Tramadol response [RCV001029248] Chr7:87600124 [GRCh38]
Chr7:87229440 [GRCh37]
Chr7:7q21.12		 likely benign|drug response
NC_000007.14:g.87713326C>T single nucleotide variant Tramadol response [RCV001029216] Chr7:87713326 [GRCh38]
Chr7:87342642 [GRCh37]
Chr7:7q21.12		 drug response
NM_000927.5(ABCB1):c.-190G>A single nucleotide variant Tramadol response [RCV001029234] Chr7:87600938 [GRCh38]
Chr7:87230254 [GRCh37]
Chr7:7q21.12		 drug response
NM_000927.5(ABCB1):c.-164C>T single nucleotide variant Tramadol response [RCV001029236] Chr7:87600912 [GRCh38]
Chr7:87230228 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.-129T>C single nucleotide variant Tramadol response [RCV001029237] Chr7:87600877 [GRCh38]
Chr7:87230193 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.68+1G>A single nucleotide variant Tramadol response [RCV001029249] Chr7:87600116 [GRCh38]
Chr7:87229432 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.69-37T>G single nucleotide variant Tramadol response [RCV001029263] Chr7:87595851 [GRCh38]
Chr7:87225167 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.69-36T>G single nucleotide variant Tramadol response [RCV001029264] Chr7:87595850 [GRCh38]
Chr7:87225166 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.69-26T>G single nucleotide variant Tramadol response [RCV001029267] Chr7:87595840 [GRCh38]
Chr7:87225156 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.117+158G>A single nucleotide variant Tramadol response [RCV001029273] Chr7:87595608 [GRCh38]
Chr7:87224924 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.117+179A>T single nucleotide variant Tramadol response [RCV001029274] Chr7:87595587 [GRCh38]
Chr7:87224903 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.117+181A>T single nucleotide variant Tramadol response [RCV001029275] Chr7:87595585 [GRCh38]
Chr7:87224901 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.117+245G>C single nucleotide variant Tramadol response [RCV001029283] Chr7:87595521 [GRCh38]
Chr7:87224837 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.117+527G>C single nucleotide variant Tramadol response [RCV001029288] Chr7:87595239 [GRCh38]
Chr7:87224555 [GRCh37]
Chr7:7q21.12		 drug response
NM_001134405.2(RUNDC3B):c.265A>T (p.Ser89Cys) single nucleotide variant not specified [RCV004661194] Chr7:87700447 [GRCh38]
Chr7:87329763 [GRCh37]
Chr7:7q21.12		 uncertain significance
NM_001348946.2(ABCB1):c.1771A>G (p.Thr591Ala) single nucleotide variant not specified [RCV004302209] Chr7:87545979 [GRCh38]
Chr7:87175295 [GRCh37]
Chr7:7q21.12		 uncertain significance
NM_001348946.2(ABCB1):c.2212-137del deletion Tramadol response [RCV001028630] Chr7:87541601 [GRCh38]
Chr7:87170917 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.2212-92C>T single nucleotide variant Tramadol response [RCV001028632] Chr7:87541556 [GRCh38]
Chr7:87170872 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.2212-78del deletion Tramadol response [RCV001028633] Chr7:87541542 [GRCh38]
Chr7:87170858 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.2234C>T (p.Pro745Leu) single nucleotide variant Tramadol response [RCV001028637] Chr7:87541442 [GRCh38]
Chr7:87170758 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.2239A>T (p.Thr747Ser) single nucleotide variant Tramadol response [RCV001028639] Chr7:87541437 [GRCh38]
Chr7:87170753 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.2686-35T>C single nucleotide variant Tramadol response [RCV001028652] Chr7:87520911 [GRCh38]
Chr7:87150227 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.2686-30C>T single nucleotide variant Tramadol response [RCV001028653] Chr7:87520906 [GRCh38]
Chr7:87150222 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.3178G>A (p.Val1060Met) single nucleotide variant Tramadol response [RCV001028665] Chr7:87515335 [GRCh38]
Chr7:87144651 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.3544C>T (p.Gln1182Ter) single nucleotide variant Tramadol response [RCV001028685] Chr7:87505989 [GRCh38]
Chr7:87135305 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.3547C>T (p.Arg1183Cys) single nucleotide variant Inflammatory bowel disease 13 [RCV002282429]|Tramadol response [RCV001028686] Chr7:87505986 [GRCh38]
Chr7:87135302 [GRCh37]
Chr7:7q21.12		 drug response|uncertain significance
NM_001348946.2(ABCB1):c.*64G>C single nucleotide variant Tramadol response [RCV001028695] Chr7:87504179 [GRCh38]
Chr7:87133495 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.*69A>C single nucleotide variant Tramadol response [RCV001028696] Chr7:87504174 [GRCh38]
Chr7:87133490 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.*186A>T single nucleotide variant Tramadol response [RCV001028706] Chr7:87504057 [GRCh38]
Chr7:87133373 [GRCh37]
Chr7:7q21.12		 drug response
NC_000007.14:g.87713450A>G single nucleotide variant Tramadol response [RCV001029211] Chr7:87713450 [GRCh38]
Chr7:87342766 [GRCh37]
Chr7:7q21.12		 drug response
NC_000007.14:g.87713378C>T single nucleotide variant Tramadol response [RCV001029214] Chr7:87713378 [GRCh38]
Chr7:87342694 [GRCh37]
Chr7:7q21.12		 drug response
NC_000007.14:g.87713328C>T single nucleotide variant Tramadol response [RCV001029215] Chr7:87713328 [GRCh38]
Chr7:87342644 [GRCh37]
Chr7:7q21.12		 drug response
NC_000007.14:g.87713324A>T single nucleotide variant Tramadol response [RCV001029217] Chr7:87713324 [GRCh38]
Chr7:87342640 [GRCh37]
Chr7:7q21.12		 drug response
NM_000927.5(ABCB1):c.-458C>T single nucleotide variant Tramadol response [RCV001029219] Chr7:87713288 [GRCh38]
Chr7:87342604 [GRCh37]
Chr7:7q21.12		 drug response
NM_000927.5(ABCB1):c.-331+51T>A single nucleotide variant Tramadol response [RCV001029225] Chr7:87713110 [GRCh38]
Chr7:87342426 [GRCh37]
Chr7:7q21.12		 drug response
NM_000927.5(ABCB1):c.-212G>A single nucleotide variant Tramadol response [RCV001029229] Chr7:87600960 [GRCh38]
Chr7:87230276 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.-6-102C>T single nucleotide variant Tramadol response [RCV001029242] Chr7:87600292 [GRCh38]
Chr7:87229608 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.69-43T>C single nucleotide variant Tramadol response [RCV001029261] Chr7:87595857 [GRCh38]
Chr7:87225173 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.69-41T>G single nucleotide variant Tramadol response [RCV001029262] Chr7:87595855 [GRCh38]
Chr7:87225171 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.69-29T>G single nucleotide variant Tramadol response [RCV001029265] Chr7:87595843 [GRCh38]
Chr7:87225159 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.117+184A>T single nucleotide variant Tramadol response [RCV001029276] Chr7:87595582 [GRCh38]
Chr7:87224898 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.117+430C>T single nucleotide variant Tramadol response [RCV001029286] Chr7:87595336 [GRCh38]
Chr7:87224652 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.68+102A>T single nucleotide variant Tramadol response [RCV001029256] Chr7:87600015 [GRCh38]
Chr7:87229331 [GRCh37]
Chr7:7q21.12		 drug response
NC_000007.14:g.87713465C>T single nucleotide variant Tramadol response [RCV001028407] Chr7:87713465 [GRCh38]
Chr7:87342781 [GRCh37]
Chr7:7q21.12		 drug response
NM_000927.5(ABCB1):c.-320C>T single nucleotide variant Tramadol response [RCV001028414] Chr7:87601068 [GRCh38]
Chr7:87230384 [GRCh37]
Chr7:7q21.12		 drug response
NM_000927.5(ABCB1):c.-273C>T single nucleotide variant Tramadol response [RCV001028420] Chr7:87601021 [GRCh38]
Chr7:87230337 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.-8A>T single nucleotide variant Tramadol response [RCV001028425] Chr7:87600756 [GRCh38]
Chr7:87230072 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.117+47C>G single nucleotide variant Tramadol response [RCV001028461] Chr7:87595719 [GRCh38]
Chr7:87225035 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.117+80del deletion Tramadol response [RCV001028462] Chr7:87595686 [GRCh38]
Chr7:87225002 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.117+151G>A single nucleotide variant Tramadol response [RCV001028467] Chr7:87595615 [GRCh38]
Chr7:87224931 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.117+671C>T single nucleotide variant Tramadol response [RCV001028476] Chr7:87595095 [GRCh38]
Chr7:87224411 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.120T>C (p.Phe40=) single nucleotide variant Tramadol response [RCV001028486] Chr7:87585678 [GRCh38]
Chr7:87214994 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.286+358T>A single nucleotide variant Tramadol response [RCV001028496] Chr7:87585154 [GRCh38]
Chr7:87214470 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.286+409C>T single nucleotide variant Tramadol response [RCV001028498] Chr7:87585103 [GRCh38]
Chr7:87214419 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.286+444G>A single nucleotide variant Tramadol response [RCV001028501] Chr7:87585068 [GRCh38]
Chr7:87214384 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.286+504del deletion Tramadol response [RCV001028502] Chr7:87585008 [GRCh38]
Chr7:87214324 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.286+553T>G single nucleotide variant Tramadol response [RCV001028503] Chr7:87584959 [GRCh38]
Chr7:87214275 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.338+305T>G single nucleotide variant Tramadol response [RCV001028509] Chr7:87569867 [GRCh38]
Chr7:87199183 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.502G>A (p.Val168Ile) single nucleotide variant Tramadol response [RCV001028523] Chr7:87566813 [GRCh38]
Chr7:87196129 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.504T>A (p.Val168=) single nucleotide variant Tramadol response [RCV001028524] Chr7:87566811 [GRCh38]
Chr7:87196127 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.703-1088T>C single nucleotide variant Tramadol response [RCV001028538] Chr7:87562475 [GRCh38]
Chr7:87191791 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.703-949G>A single nucleotide variant Tramadol response [RCV001028543] Chr7:87562336 [GRCh38]
Chr7:87191652 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.751G>A (p.Gly251Arg) single nucleotide variant Tramadol response [RCV001028546] Chr7:87561339 [GRCh38]
Chr7:87190655 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.828-719C>A single nucleotide variant Tramadol response [RCV001028550] Chr7:87554651 [GRCh38]
Chr7:87183967 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.828-662A>T single nucleotide variant Tramadol response [RCV001028552] Chr7:87554594 [GRCh38]
Chr7:87183910 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.828-541C>T single nucleotide variant Tramadol response [RCV001028555] Chr7:87554473 [GRCh38]
Chr7:87183789 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1000-25G>A single nucleotide variant Tramadol response [RCV001028566] Chr7:87550863 [GRCh38]
Chr7:87180179 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1113+54del deletion Tramadol response [RCV001028575] Chr7:87550671 [GRCh38]
Chr7:87179987 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1350+42G>T single nucleotide variant Tramadol response [RCV001028596] Chr7:87550129 [GRCh38]
Chr7:87179445 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1712T>G (p.Val571Gly) single nucleotide variant Tramadol response [RCV001028607] Chr7:87549361 [GRCh38]
Chr7:87178677 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1725+136G>T single nucleotide variant Tramadol response [RCV001028610] Chr7:87549212 [GRCh38]
Chr7:87178528 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1725+154A>G single nucleotide variant Tramadol response [RCV001028611] Chr7:87549194 [GRCh38]
Chr7:87178510 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1997G>A (p.Arg666Lys) single nucleotide variant Tramadol response [RCV001028616] Chr7:87544890 [GRCh38]
Chr7:87174206 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.2064+73A>G single nucleotide variant Tramadol response [RCV001028622] Chr7:87544750 [GRCh38]
Chr7:87174066 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.2065-87T>A single nucleotide variant Tramadol response [RCV001028627] Chr7:87544362 [GRCh38]
Chr7:87173678 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.781A>G (p.Ile261Val) single nucleotide variant not provided [RCV000883246] Chr7:87561309 [GRCh38]
Chr7:87190625 [GRCh37]
Chr7:7q21.12		 benign
NM_001348946.2(ABCB1):c.3085-10C>T single nucleotide variant not provided [RCV000936625] Chr7:87515438 [GRCh38]
Chr7:87144754 [GRCh37]
Chr7:7q21.12		 likely benign
NM_001348946.2(ABCB1):c.3751G>A (p.Val1251Ile) single nucleotide variant not provided [RCV000959670] Chr7:87504335 [GRCh38]
Chr7:87133651 [GRCh37]
Chr7:7q21.12		 benign
NM_001348946.2(ABCB1):c.738G>A (p.Ala246=) single nucleotide variant ABCB1-related disorder [RCV003932988]|not provided [RCV000911726] Chr7:87561352 [GRCh38]
Chr7:87190668 [GRCh37]
Chr7:7q21.12		 likely benign
NM_001134405.2(RUNDC3B):c.378A>T (p.Arg126Ser) single nucleotide variant not specified [RCV004329277] Chr7:87710575 [GRCh38]
Chr7:87339891 [GRCh37]
Chr7:7q21.12		 uncertain significance
NM_000927.5(ABCB1):c.-331+67T>G single nucleotide variant Tramadol response [RCV001028408] Chr7:87713094 [GRCh38]
Chr7:87342410 [GRCh37]
Chr7:7q21.12		 drug response
NM_000927.5(ABCB1):c.-301C>T single nucleotide variant Tramadol response [RCV001028416] Chr7:87601049 [GRCh38]
Chr7:87230365 [GRCh37]
Chr7:7q21.12		 drug response
NM_000927.5(ABCB1):c.-291C>T single nucleotide variant Tramadol response [RCV001028417] Chr7:87601039 [GRCh38]
Chr7:87230355 [GRCh37]
Chr7:7q21.12		 drug response
NM_000927.5(ABCB1):c.-263C>T single nucleotide variant Tramadol response [RCV001028423] Chr7:87601011 [GRCh38]
Chr7:87230327 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.-7+157T>C single nucleotide variant Tramadol response [RCV001028432] Chr7:87600598 [GRCh38]
Chr7:87229914 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.-7+245A>C single nucleotide variant Tramadol response [RCV001028437] Chr7:87600510 [GRCh38]
Chr7:87229826 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.68+417C>A single nucleotide variant Tramadol response [RCV001028443] Chr7:87599700 [GRCh38]
Chr7:87229016 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.68+429C>T single nucleotide variant Tramadol response [RCV001028446] Chr7:87599688 [GRCh38]
Chr7:87229004 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.68+434A>G single nucleotide variant Tramadol response [RCV001028449] Chr7:87599683 [GRCh38]
Chr7:87228999 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.69-781G>A single nucleotide variant Tramadol response [RCV001028451] Chr7:87596595 [GRCh38]
Chr7:87225911 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.69-778G>A single nucleotide variant Tramadol response [RCV001028454] Chr7:87596592 [GRCh38]
Chr7:87225908 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.117+36C>T single nucleotide variant Tramadol response [RCV001028460] Chr7:87595730 [GRCh38]
Chr7:87225046 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.117+154G>A single nucleotide variant Tramadol response [RCV001028469] Chr7:87595612 [GRCh38]
Chr7:87224928 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.117+570T>A single nucleotide variant Tramadol response [RCV001028473] Chr7:87595196 [GRCh38]
Chr7:87224512 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.117+591G>A single nucleotide variant Tramadol response [RCV001028474] Chr7:87595175 [GRCh38]
Chr7:87224491 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.117+673T>C single nucleotide variant Tramadol response [RCV001028477] Chr7:87595093 [GRCh38]
Chr7:87224409 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.118-3del deletion Tramadol response [RCV001028485] Chr7:87585683 [GRCh38]
Chr7:87214999 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.286+150G>T single nucleotide variant Tramadol response [RCV001028488] Chr7:87585362 [GRCh38]
Chr7:87214678 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.286+218A>G single nucleotide variant Tramadol response [RCV001028489] Chr7:87585294 [GRCh38]
Chr7:87214610 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.286+324C>G single nucleotide variant Tramadol response [RCV001028492] Chr7:87585188 [GRCh38]
Chr7:87214504 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.286+384C>A single nucleotide variant Tramadol response [RCV001028497] Chr7:87585128 [GRCh38]
Chr7:87214444 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.286+419A>G single nucleotide variant Tramadol response [RCV001028499] Chr7:87585093 [GRCh38]
Chr7:87214409 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.286+436G>A single nucleotide variant Tramadol response [RCV001028500] Chr7:87585076 [GRCh38]
Chr7:87214392 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.338+223A>T single nucleotide variant Tramadol response [RCV001028506] Chr7:87569949 [GRCh38]
Chr7:87199265 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.338+224G>T single nucleotide variant Tramadol response [RCV001028507] Chr7:87569948 [GRCh38]
Chr7:87199264 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.338+293G>A single nucleotide variant Tramadol response [RCV001028508] Chr7:87569879 [GRCh38]
Chr7:87199195 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.338+329T>G single nucleotide variant Tramadol response [RCV001028512] Chr7:87569843 [GRCh38]
Chr7:87199159 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.338+332T>A single nucleotide variant Tramadol response [RCV001028513] Chr7:87569840 [GRCh38]
Chr7:87199156 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.338+333G>T single nucleotide variant Tramadol response [RCV001028514] Chr7:87569839 [GRCh38]
Chr7:87199155 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.338+335C>A single nucleotide variant Tramadol response [RCV001028516] Chr7:87569837 [GRCh38]
Chr7:87199153 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.414G>T (p.Leu138=) single nucleotide variant Tramadol response [RCV001028519] Chr7:87566901 [GRCh38]
Chr7:87196217 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.702+385A>G single nucleotide variant Tramadol response [RCV001028535] Chr7:87565685 [GRCh38]
Chr7:87195001 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.732C>A (p.Leu244=) single nucleotide variant Tramadol response [RCV001028545] Chr7:87561358 [GRCh38]
Chr7:87190674 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.828-193C>T single nucleotide variant Tramadol response [RCV001028559] Chr7:87554125 [GRCh38]
Chr7:87183441 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.828-147C>T single nucleotide variant Tramadol response [RCV001028561] Chr7:87554079 [GRCh38]
Chr7:87183395 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1064T>A (p.Phe355Tyr) single nucleotide variant Tramadol response [RCV001028570] Chr7:87550774 [GRCh38]
Chr7:87180090 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1113+19T>A single nucleotide variant Tramadol response [RCV001028573] Chr7:87550706 [GRCh38]
Chr7:87180022 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1154C>T (p.Pro385Leu) single nucleotide variant Tramadol response [RCV001028580] Chr7:87550538 [GRCh38]
Chr7:87179854 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1299G>A (p.Lys433=) single nucleotide variant Tramadol response [RCV001028583] Chr7:87550222 [GRCh38]
Chr7:87179538 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1302C>T (p.Ser434=) single nucleotide variant Tramadol response [RCV001028585] Chr7:87550219 [GRCh38]
Chr7:87179535 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1327C>A (p.Leu443Ile) single nucleotide variant Tramadol response [RCV001028589] Chr7:87550194 [GRCh38]
Chr7:87179510 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1350+12C>T single nucleotide variant Tramadol response [RCV001028591] Chr7:87550159 [GRCh38]
Chr7:87179475 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1555-124A>T single nucleotide variant Tramadol response [RCV001028597] Chr7:87549642 [GRCh38]
Chr7:87178958 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1555-41G>A single nucleotide variant Tramadol response [RCV001028599] Chr7:87549559 [GRCh38]
Chr7:87178875 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1555-10T>C single nucleotide variant Tramadol response [RCV001028600] Chr7:87549528 [GRCh38]
Chr7:87178844 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1585G>A (p.Ala529Thr) single nucleotide variant Tramadol response [RCV001028602] Chr7:87549488 [GRCh38]
Chr7:87178804 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1600G>A (p.Gly534Arg) single nucleotide variant Tramadol response [RCV001028603] Chr7:87549473 [GRCh38]
Chr7:87178789 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1725+73T>A single nucleotide variant Tramadol response [RCV001028609] Chr7:87549275 [GRCh38]
Chr7:87178591 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1888-12T>C single nucleotide variant Tramadol response [RCV001028614] Chr7:87545011 [GRCh38]
Chr7:87174327 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.2064+7A>G single nucleotide variant Tramadol response [RCV001028618] Chr7:87544816 [GRCh38]
Chr7:87174132 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.2065-112A>G single nucleotide variant Tramadol response [RCV001028624] Chr7:87544387 [GRCh38]
Chr7:87173703 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.2211+29A>G single nucleotide variant Tramadol response [RCV001028628] Chr7:87544100 [GRCh38]
Chr7:87173416 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.2212-40C>T single nucleotide variant Tramadol response [RCV001028635] Chr7:87541504 [GRCh38]
Chr7:87170820 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.2274G>A (p.Leu758=) single nucleotide variant Tramadol response [RCV001028641] Chr7:87541402 [GRCh38]
Chr7:87170718 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.2618T>G (p.Val873Gly) single nucleotide variant Tramadol response [RCV001028644] Chr7:87531361 [GRCh38]
Chr7:87160677 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.2656G>A (p.Asp886Asn) single nucleotide variant Tramadol response [RCV001028648] Chr7:87531323 [GRCh38]
Chr7:87160639 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.2685+69C>T single nucleotide variant Tramadol response [RCV001028650] Chr7:87531225 [GRCh38]
Chr7:87160541 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.2685+70T>C single nucleotide variant Tramadol response [RCV001028651] Chr7:87531224 [GRCh38]
Chr7:87160540 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.2688C>A (p.Ile896=) single nucleotide variant Tramadol response [RCV001028655] Chr7:87520874 [GRCh38]
Chr7:87150190 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.3085-61G>A single nucleotide variant Tramadol response [RCV001028660] Chr7:87515489 [GRCh38]
Chr7:87144805 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.3138C>A (p.Thr1046=) single nucleotide variant Tramadol response [RCV001028663] Chr7:87515375 [GRCh38]
Chr7:87144691 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.3277A>G (p.Lys1093Glu) single nucleotide variant Tramadol response [RCV001028673] Chr7:87515236 [GRCh38]
Chr7:87144552 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.3281T>G (p.Val1094Gly) single nucleotide variant Tramadol response [RCV001028674] Chr7:87515232 [GRCh38]
Chr7:87144548 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.3541A>T (p.Lys1181Ter) single nucleotide variant Tramadol response [RCV001028683] Chr7:87505992 [GRCh38]
Chr7:87135308 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.3554C>A (p.Ala1185Asp) single nucleotide variant Tramadol response [RCV001028687] Chr7:87505979 [GRCh38]
Chr7:87135295 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.*91G>C single nucleotide variant Tramadol response [RCV001028698] Chr7:87504152 [GRCh38]
Chr7:87133468 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.*155G>A single nucleotide variant Tramadol response [RCV001028700] Chr7:87504088 [GRCh38]
Chr7:87133404 [GRCh37]
Chr7:7q21.12		 drug response
NC_000007.14:g.87713462C>T single nucleotide variant Tramadol response [RCV001029210] Chr7:87713462 [GRCh38]
Chr7:87342778 [GRCh37]
Chr7:7q21.12		 drug response
NC_000007.14:g.87713441del deletion Tramadol response [RCV001029212] Chr7:87713439 [GRCh38]
Chr7:87342755 [GRCh37]
Chr7:7q21.12		 drug response
NM_000927.5(ABCB1):c.-364G>A single nucleotide variant Tramadol response [RCV001029223] Chr7:87713194 [GRCh38]
Chr7:87342510 [GRCh37]
Chr7:7q21.12		 drug response
NM_000927.5(ABCB1):c.-230T>C single nucleotide variant Tramadol response [RCV001029227] Chr7:87600978 [GRCh38]
Chr7:87230294 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.-95G>T single nucleotide variant Tramadol response [RCV001029240] Chr7:87600843 [GRCh38]
Chr7:87230159 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.68+29T>G single nucleotide variant Tramadol response [RCV001029253] Chr7:87600088 [GRCh38]
Chr7:87229404 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.69-775T>C single nucleotide variant Tramadol response [RCV001029257] Chr7:87596589 [GRCh38]
Chr7:87225905 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.69-771T>C single nucleotide variant Tramadol response [RCV001029258] Chr7:87596585 [GRCh38]
Chr7:87225901 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.69-76C>A single nucleotide variant Tramadol response [RCV001029259] Chr7:87595890 [GRCh38]
Chr7:87225206 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.69-62T>A single nucleotide variant Tramadol response [RCV001029260] Chr7:87595876 [GRCh38]
Chr7:87225192 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.69-22T>G single nucleotide variant Tramadol response [RCV001029269] Chr7:87595836 [GRCh38]
Chr7:87225152 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.69-19T>G single nucleotide variant Tramadol response [RCV001029270] Chr7:87595833 [GRCh38]
Chr7:87225149 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.81del (p.Lys28fs) deletion Tramadol response [RCV001029272] Chr7:87595802 [GRCh38]
Chr7:87225118 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.117+187A>T single nucleotide variant Tramadol response [RCV001029278] Chr7:87595579 [GRCh38]
Chr7:87224895 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.117+206T>G single nucleotide variant Tramadol response [RCV001029280] Chr7:87595560 [GRCh38]
Chr7:87224876 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.117+212A>G single nucleotide variant Tramadol response [RCV001029281] Chr7:87595554 [GRCh38]
Chr7:87224870 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.117+398G>A single nucleotide variant Tramadol response [RCV001029285] Chr7:87595368 [GRCh38]
Chr7:87224684 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.159G>T (p.Val53=) single nucleotide variant Tramadol response [RCV001029289] Chr7:87585639 [GRCh38]
Chr7:87214955 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.286+30G>A single nucleotide variant Tramadol response [RCV001029299] Chr7:87585482 [GRCh38]
Chr7:87214798 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.286+107C>T single nucleotide variant Tramadol response [RCV001029302] Chr7:87585405 [GRCh38]
Chr7:87214721 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.286+130T>C single nucleotide variant Tramadol response [RCV001029303] Chr7:87585382 [GRCh38]
Chr7:87214698 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.287-94C>T single nucleotide variant Tramadol response [RCV001029310] Chr7:87570317 [GRCh38]
Chr7:87199633 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.338+97G>T single nucleotide variant Tramadol response [RCV001029316] Chr7:87570075 [GRCh38]
Chr7:87199391 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.596C>T (p.Thr199Ile) single nucleotide variant Tramadol response [RCV001029341] Chr7:87566176 [GRCh38]
Chr7:87195492 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.827+10del deletion Tramadol response [RCV001029352] Chr7:87561253 [GRCh38]
Chr7:87190569 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.828-38T>A single nucleotide variant Tramadol response [RCV001029367] Chr7:87553970 [GRCh38]
Chr7:87183286 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.828-37A>C single nucleotide variant Tramadol response [RCV001029368] Chr7:87553969 [GRCh38]
Chr7:87183285 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.831C>T (p.Tyr277=) single nucleotide variant Tramadol response [RCV001029369] Chr7:87553929 [GRCh38]
Chr7:87183245 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1000-100del deletion Tramadol response [RCV001029378] Chr7:87550938 [GRCh38]
Chr7:87180254 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1554+34del deletion Tramadol response [RCV001029404] Chr7:87549817 [GRCh38]
Chr7:87179133 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1554+130C>A single nucleotide variant Tramadol response [RCV001029413] Chr7:87549721 [GRCh38]
Chr7:87179037 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1726-585G>T single nucleotide variant Tramadol response [RCV001029416] Chr7:87546609 [GRCh38]
Chr7:87175925 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1887+33T>C single nucleotide variant Tramadol response [RCV001029427] Chr7:87545830 [GRCh38]
Chr7:87175146 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.2065-79T>A single nucleotide variant Tramadol response [RCV001029431] Chr7:87544354 [GRCh38]
Chr7:87173670 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.2211+9G>T single nucleotide variant Tramadol response [RCV001029440] Chr7:87544120 [GRCh38]
Chr7:87173436 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.2791T>C (p.Ser931Pro) single nucleotide variant Tramadol response [RCV001029474] Chr7:87519462 [GRCh38]
Chr7:87148778 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.3081G>A (p.Met1027Ile) single nucleotide variant Tramadol response [RCV001029482] Chr7:87516512 [GRCh38]
Chr7:87145828 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.*272T>C single nucleotide variant Tramadol response [RCV001029524] Chr7:87503971 [GRCh38]
Chr7:87133287 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.*379G>A single nucleotide variant Tramadol response [RCV001029527] Chr7:87503864 [GRCh38]
Chr7:87133180 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1300A>C (p.Ser434Arg) single nucleotide variant Tramadol response [RCV001028584] Chr7:87550221 [GRCh38]
Chr7:87179537 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1342G>T (p.Glu448Ter) single nucleotide variant Tramadol response [RCV001028590] Chr7:87550179 [GRCh38]
Chr7:87179495 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1350+36T>C single nucleotide variant Tramadol response [RCV001028593] Chr7:87550135 [GRCh38]
Chr7:87179451 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.2064+24G>C single nucleotide variant Tramadol response [RCV001028620] Chr7:87544799 [GRCh38]
Chr7:87174115 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.2236G>A (p.Glu746Lys) single nucleotide variant Tramadol response [RCV001028638] Chr7:87541440 [GRCh38]
Chr7:87170756 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.2647G>A (p.Ala883Thr) single nucleotide variant Tramadol response [RCV001028647] Chr7:87531332 [GRCh38]
Chr7:87160648 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.3185A>G (p.Lys1062Arg) single nucleotide variant Tramadol response [RCV001028666] Chr7:87515328 [GRCh38]
Chr7:87144644 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.*20T>C single nucleotide variant Tramadol response [RCV001028691] Chr7:87504223 [GRCh38]
Chr7:87133539 [GRCh37]
Chr7:7q21.12		 drug response
NM_000927.5(ABCB1):c.-372T>G single nucleotide variant Tramadol response [RCV001029222] Chr7:87713202 [GRCh38]
Chr7:87342518 [GRCh37]
Chr7:7q21.12		 drug response
NM_000927.5(ABCB1):c.-214T>A single nucleotide variant Tramadol response [RCV001029228] Chr7:87600962 [GRCh38]
Chr7:87230278 [GRCh37]
Chr7:7q21.12		 drug response
NM_000927.5(ABCB1):c.-202G>A single nucleotide variant Tramadol response [RCV001029232] Chr7:87600950 [GRCh38]
Chr7:87230266 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.-115A>G single nucleotide variant Tramadol response [RCV001029238] Chr7:87600863 [GRCh38]
Chr7:87230179 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.-112T>C single nucleotide variant Tramadol response [RCV001029239] Chr7:87600860 [GRCh38]
Chr7:87230176 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.68+38G>A single nucleotide variant Tramadol response [RCV001029255] Chr7:87600079 [GRCh38]
Chr7:87229395 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.69-18T>G single nucleotide variant Tramadol response [RCV001029271] Chr7:87595832 [GRCh38]
Chr7:87225148 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.117+185C>A single nucleotide variant Tramadol response [RCV001029277] Chr7:87595581 [GRCh38]
Chr7:87224897 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.117+214A>C single nucleotide variant Tramadol response [RCV001029282] Chr7:87595552 [GRCh38]
Chr7:87224868 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.117+502A>G single nucleotide variant Tramadol response [RCV001029287] Chr7:87595264 [GRCh38]
Chr7:87224580 [GRCh37]
Chr7:7q21.12		 drug response
NM_000927.5(ABCB1):c.-331+79T>A single nucleotide variant Tramadol response [RCV001028410] Chr7:87713082 [GRCh38]
Chr7:87342398 [GRCh37]
Chr7:7q21.12		 drug response
NM_000927.5(ABCB1):c.-331+84A>C single nucleotide variant Tramadol response [RCV001028413] Chr7:87713077 [GRCh38]
Chr7:87342393 [GRCh37]
Chr7:7q21.12		 drug response
NM_000927.5(ABCB1):c.-313C>T single nucleotide variant Tramadol response [RCV001028415] Chr7:87601061 [GRCh38]
Chr7:87230377 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.-7+10C>T single nucleotide variant Tramadol response [RCV001028426] Chr7:87600745 [GRCh38]
Chr7:87230061 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.-7+83G>A single nucleotide variant Tramadol response [RCV001028429] Chr7:87600672 [GRCh38]
Chr7:87229988 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.-7+164A>G single nucleotide variant Tramadol response [RCV001028435] Chr7:87600591 [GRCh38]
Chr7:87229907 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.-6-184A>C single nucleotide variant Tramadol response [RCV001028438] Chr7:87600374 [GRCh38]
Chr7:87229690 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.-6-106C>T single nucleotide variant Tramadol response [RCV001028439] Chr7:87600296 [GRCh38]
Chr7:87229612 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.68+299C>A single nucleotide variant Tramadol response [RCV001028440] Chr7:87599818 [GRCh38]
Chr7:87229134 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.69-779A>G single nucleotide variant Tramadol response [RCV001028453] Chr7:87596593 [GRCh38]
Chr7:87225909 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.117+94G>T single nucleotide variant Tramadol response [RCV001028463] Chr7:87595672 [GRCh38]
Chr7:87224988 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.117+120A>G single nucleotide variant Tramadol response [RCV001028464] Chr7:87595646 [GRCh38]
Chr7:87224962 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.117+130G>A single nucleotide variant Tramadol response [RCV001028465] Chr7:87595636 [GRCh38]
Chr7:87224952 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.118-139T>A single nucleotide variant Tramadol response [RCV001028478] Chr7:87585819 [GRCh38]
Chr7:87215135 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.118-106G>A single nucleotide variant Tramadol response [RCV001028480] Chr7:87585786 [GRCh38]
Chr7:87215102 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.286+322T>C single nucleotide variant Tramadol response [RCV001028491] Chr7:87585190 [GRCh38]
Chr7:87214506 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.286+330A>G single nucleotide variant Tramadol response [RCV001028495] Chr7:87585182 [GRCh38]
Chr7:87214498 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.521G>A (p.Arg174Gln) single nucleotide variant ABCB1-related disorder [RCV003953432]|Tramadol response [RCV001028525] Chr7:87566794 [GRCh38]
Chr7:87196110 [GRCh37]
Chr7:7q21.12		 drug response|uncertain significance
NM_001348946.2(ABCB1):c.530+203G>A single nucleotide variant Tramadol response [RCV001028532] Chr7:87566582 [GRCh38]
Chr7:87195898 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.702+389T>C single nucleotide variant Tramadol response [RCV001028536] Chr7:87565681 [GRCh38]
Chr7:87194997 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.703-950A>G single nucleotide variant Tramadol response [RCV001028542] Chr7:87562337 [GRCh38]
Chr7:87191653 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.762T>C (p.Ala254=) single nucleotide variant Tramadol response [RCV001028548] Chr7:87561328 [GRCh38]
Chr7:87190644 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.772T>G (p.Leu258Val) single nucleotide variant Tramadol response [RCV001028549] Chr7:87561318 [GRCh38]
Chr7:87190634 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.828-57C>T single nucleotide variant Tramadol response [RCV001028565] Chr7:87553989 [GRCh38]
Chr7:87183305 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1024del (p.Ala342fs) deletion Tramadol response [RCV001028568] Chr7:87550814 [GRCh38]
Chr7:87180130 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.2065-83_2065-81del deletion Tramadol response [RCV001029430] Chr7:87544356..87544358 [GRCh38]
Chr7:87173672..87173674 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.2120A>T (p.Glu707Val) single nucleotide variant Tramadol response [RCV001029434] Chr7:87544220 [GRCh38]
Chr7:87173536 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.2150G>A (p.Cys717Tyr) single nucleotide variant Tramadol response [RCV001029438] Chr7:87544190 [GRCh38]
Chr7:87173506 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.2211+28T>G single nucleotide variant Tramadol response [RCV001029448] Chr7:87544101 [GRCh38]
Chr7:87173417 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.2320-34C>A single nucleotide variant Tramadol response [RCV001029451] Chr7:87539379 [GRCh38]
Chr7:87168695 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.2787-8C>A single nucleotide variant Tramadol response [RCV001029473] Chr7:87519474 [GRCh38]
Chr7:87148790 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.3691G>A (p.Ala1231Thr) single nucleotide variant Tramadol response [RCV001029511] Chr7:87504395 [GRCh38]
Chr7:87133711 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.*189A>C single nucleotide variant Tramadol response [RCV001029520] Chr7:87504054 [GRCh38]
Chr7:87133370 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.*363A>C single nucleotide variant Tramadol response [RCV001029526] Chr7:87503880 [GRCh38]
Chr7:87133196 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.339-423T>A single nucleotide variant Tramadol response [RCV001029323] Chr7:87567399 [GRCh38]
Chr7:87196715 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.339-276G>A single nucleotide variant Tramadol response [RCV001029331] Chr7:87567252 [GRCh38]
Chr7:87196568 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.702+34G>A single nucleotide variant Tramadol response [RCV001029347] Chr7:87566036 [GRCh38]
Chr7:87195352 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.827+789G>T single nucleotide variant Tramadol response [RCV001029360] Chr7:87560474 [GRCh38]
Chr7:87189790 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.828-753G>A single nucleotide variant Tramadol response [RCV001029365] Chr7:87554685 [GRCh38]
Chr7:87184001 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.981T>C (p.Ser327=) single nucleotide variant Tramadol response [RCV001029374] Chr7:87553779 [GRCh38]
Chr7:87183095 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.999+38A>C single nucleotide variant Tramadol response [RCV001029376] Chr7:87553723 [GRCh38]
Chr7:87183039 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1000-42C>A single nucleotide variant Tramadol response [RCV001029381] Chr7:87550880 [GRCh38]
Chr7:87180196 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1210C>T (p.Arg404Ter) single nucleotide variant Tramadol response [RCV001029386] Chr7:87550482 [GRCh38]
Chr7:87179798 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1223A>G (p.Lys408Arg) single nucleotide variant Tramadol response [RCV001029387] Chr7:87550469 [GRCh38]
Chr7:87179785 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1225-67A>C single nucleotide variant Tramadol response [RCV001029389] Chr7:87550363 [GRCh38]
Chr7:87179679 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1554+24T>C single nucleotide variant Tramadol response [RCV001029403] Chr7:87549827 [GRCh38]
Chr7:87179143 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1554+49G>A single nucleotide variant Tramadol response [RCV001029405] Chr7:87549802 [GRCh38]
Chr7:87179118 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1725+160T>C single nucleotide variant Tramadol response [RCV001029414] Chr7:87549188 [GRCh38]
Chr7:87178504 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1792A>G (p.Ile598Val) single nucleotide variant Tramadol response [RCV001029423] Chr7:87545958 [GRCh38]
Chr7:87175274 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1888-75C>T single nucleotide variant Tramadol response [RCV001029429] Chr7:87545074 [GRCh38]
Chr7:87174390 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.2140G>A (p.Gly714Ser) single nucleotide variant Tramadol response [RCV001029436] Chr7:87544200 [GRCh38]
Chr7:87173516 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.2211+24G>T single nucleotide variant Tramadol response [RCV001029445] Chr7:87544105 [GRCh38]
Chr7:87173421 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.2397+27G>T single nucleotide variant Tramadol response [RCV001029461] Chr7:87539241 [GRCh38]
Chr7:87168557 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.2836C>T (p.Gln946Ter) single nucleotide variant Tramadol response [RCV001029475] Chr7:87519417 [GRCh38]
Chr7:87148733 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.2927+33A>T single nucleotide variant Tramadol response [RCV001029479] Chr7:87519293 [GRCh38]
Chr7:87148609 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.3351C>G (p.Ser1117=) single nucleotide variant Tramadol response [RCV001029498] Chr7:87509413 [GRCh38]
Chr7:87138729 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.3352C>G (p.Gln1118Glu) single nucleotide variant Tramadol response [RCV001029499]|not specified [RCV004030903] Chr7:87509412 [GRCh38]
Chr7:87138728 [GRCh37]
Chr7:7q21.12		 drug response|uncertain significance
NM_001348946.2(ABCB1):c.3643C>A (p.Gln1215Lys) single nucleotide variant Tramadol response [RCV001029507] Chr7:87504443 [GRCh38]
Chr7:87133759 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.3746G>A (p.Gly1249Asp) single nucleotide variant Tramadol response [RCV001029512] Chr7:87504340 [GRCh38]
Chr7:87133656 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.*193A>G single nucleotide variant Tramadol response [RCV001029521] Chr7:87504050 [GRCh38]
Chr7:87133366 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.*223C>T single nucleotide variant Tramadol response [RCV001029522] Chr7:87504020 [GRCh38]
Chr7:87133336 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.*421T>C single nucleotide variant Tramadol response [RCV001029530] Chr7:87503822 [GRCh38]
Chr7:87133138 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.286+5G>A single nucleotide variant Tramadol response [RCV001029298] Chr7:87585507 [GRCh38]
Chr7:87214823 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.287-111C>T single nucleotide variant Tramadol response [RCV001029308] Chr7:87570334 [GRCh38]
Chr7:87199650 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.338+103C>T single nucleotide variant Tramadol response [RCV001029317] Chr7:87570069 [GRCh38]
Chr7:87199385 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.339-342G>A single nucleotide variant Tramadol response [RCV001029328] Chr7:87567318 [GRCh38]
Chr7:87196634 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.531-268A>T single nucleotide variant Tramadol response [RCV001029338] Chr7:87566509 [GRCh38]
Chr7:87195825 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.658G>A (p.Ala220Thr) single nucleotide variant Tramadol response [RCV001029345]|not specified [RCV004639429] Chr7:87566114 [GRCh38]
Chr7:87195430 [GRCh37]
Chr7:7q21.12		 drug response|uncertain significance
NM_001348946.2(ABCB1):c.796G>A (p.Ala266Thr) single nucleotide variant Tramadol response [RCV001029351] Chr7:87561294 [GRCh38]
Chr7:87190610 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.827+652A>T single nucleotide variant Tramadol response [RCV001029357] Chr7:87560611 [GRCh38]
Chr7:87189927 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1164T>A (p.Ile388=) single nucleotide variant Tramadol response [RCV001029384] Chr7:87550528 [GRCh38]
Chr7:87179844 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1554+73G>A single nucleotide variant Tramadol response [RCV001029407] Chr7:87549778 [GRCh38]
Chr7:87179094 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1554+122G>A single nucleotide variant Tramadol response [RCV001029411] Chr7:87549729 [GRCh38]
Chr7:87179045 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1554+127C>T single nucleotide variant Tramadol response [RCV001029412] Chr7:87549724 [GRCh38]
Chr7:87179040 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1224+64G>A single nucleotide variant Tramadol response [RCV001029388] Chr7:87550404 [GRCh38]
Chr7:87179720 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1225-42C>T single nucleotide variant Tramadol response [RCV001029390] Chr7:87550338 [GRCh38]
Chr7:87179654 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1225A>T (p.Ile409Phe) single nucleotide variant Tramadol response [RCV001029393] Chr7:87550296 [GRCh38]
Chr7:87179612 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1259G>A (p.Gly420Glu) single nucleotide variant Tramadol response [RCV001029396] Chr7:87550262 [GRCh38]
Chr7:87179578 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1260G>A (p.Gly420=) single nucleotide variant Tramadol response [RCV001029397] Chr7:87550261 [GRCh38]
Chr7:87179577 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1351-49del deletion Tramadol response [RCV001029400] Chr7:87550103 [GRCh38]
Chr7:87179419 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1762C>T (p.Arg588Cys) single nucleotide variant Tramadol response [RCV001029421] Chr7:87545988 [GRCh38]
Chr7:87175304 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.2211+18T>A single nucleotide variant Tramadol response [RCV001029442] Chr7:87544111 [GRCh38]
Chr7:87173427 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.2341G>A (p.Gly781Arg) single nucleotide variant Tramadol response [RCV001029453] Chr7:87539324 [GRCh38]
Chr7:87168640 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.2398-1G>A single nucleotide variant Tramadol response [RCV001029463] Chr7:87536542 [GRCh38]
Chr7:87165858 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.2481G>A (p.Gly827=) single nucleotide variant Tramadol response [RCV001029465] Chr7:87536458 [GRCh38]
Chr7:87165774 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.2954C>A (p.Ala985Asp) single nucleotide variant Tramadol response [RCV001029481] Chr7:87516639 [GRCh38]
Chr7:87145955 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.3085-68A>C single nucleotide variant Tramadol response [RCV001029487] Chr7:87515496 [GRCh38]
Chr7:87144812 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.3377G>T (p.Ser1126Ile) single nucleotide variant Tramadol response [RCV001029503] Chr7:87509387 [GRCh38]
Chr7:87138703 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.3649G>A (p.Ala1217Thr) single nucleotide variant Tramadol response [RCV001029508] Chr7:87504437 [GRCh38]
Chr7:87133753 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.244G>A (p.Ala82Thr) single nucleotide variant Tramadol response [RCV001029294] Chr7:87585554 [GRCh38]
Chr7:87214870 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.338+122T>C single nucleotide variant Tramadol response [RCV001029318] Chr7:87570050 [GRCh38]
Chr7:87199366 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.339-436del deletion Tramadol response [RCV001029320] Chr7:87567412 [GRCh38]
Chr7:87196728 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.339-429del deletion Tramadol response [RCV001029321] Chr7:87567405 [GRCh38]
Chr7:87196721 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.339-412T>A single nucleotide variant Tramadol response [RCV001029324] Chr7:87567388 [GRCh38]
Chr7:87196704 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.339-294A>C single nucleotide variant Tramadol response [RCV001029330] Chr7:87567270 [GRCh38]
Chr7:87196586 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.827+52A>C single nucleotide variant Tramadol response [RCV001029355] Chr7:87561211 [GRCh38]
Chr7:87190527 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.827+792G>A single nucleotide variant Tramadol response [RCV001029362] Chr7:87560471 [GRCh38]
Chr7:87189787 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.901G>A (p.Ala301Thr) single nucleotide variant Tramadol response [RCV001029370] Chr7:87553859 [GRCh38]
Chr7:87183175 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.973G>A (p.Glu325Lys) single nucleotide variant Tramadol response [RCV001029373] Chr7:87553787 [GRCh38]
Chr7:87183103 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1000-44G>A single nucleotide variant Tramadol response [RCV001029380] Chr7:87550882 [GRCh38]
Chr7:87180198 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1000-29G>A single nucleotide variant Tramadol response [RCV001029382] Chr7:87550867 [GRCh38]
Chr7:87180183 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.286+139A>G single nucleotide variant Tramadol response [RCV001029304] Chr7:87585373 [GRCh38]
Chr7:87214689 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.338+26G>T single nucleotide variant Tramadol response [RCV001029314] Chr7:87570146 [GRCh38]
Chr7:87199462 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.338+68A>C single nucleotide variant Tramadol response [RCV001029315] Chr7:87570104 [GRCh38]
Chr7:87199420 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.338+123A>G single nucleotide variant Tramadol response [RCV001029319] Chr7:87570049 [GRCh38]
Chr7:87199365 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.339-406T>A single nucleotide variant Tramadol response [RCV001029325] Chr7:87567382 [GRCh38]
Chr7:87196698 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.339-392C>A single nucleotide variant Tramadol response [RCV001029326] Chr7:87567368 [GRCh38]
Chr7:87196684 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.530+272A>G single nucleotide variant Tramadol response [RCV001029337] Chr7:87566513 [GRCh38]
Chr7:87195829 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.531-62T>C single nucleotide variant Tramadol response [RCV001029339] Chr7:87566303 [GRCh38]
Chr7:87195619 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.702+30A>T single nucleotide variant Tramadol response [RCV001029346] Chr7:87566040 [GRCh38]
Chr7:87195356 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.828-880T>G single nucleotide variant Tramadol response [RCV001029364] Chr7:87554812 [GRCh38]
Chr7:87184128 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1161T>A (p.Asn387Lys) single nucleotide variant Tramadol response [RCV001029383] Chr7:87550531 [GRCh38]
Chr7:87179847 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1255A>G (p.Ser419Gly) single nucleotide variant Tramadol response [RCV001029395] Chr7:87550266 [GRCh38]
Chr7:87179582 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1350+44C>T single nucleotide variant Tramadol response [RCV001029398] Chr7:87550127 [GRCh38]
Chr7:87550127..87550128 [GRCh38]
Chr7:87179443 [GRCh37]
Chr7:87179443..87179444 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1350+46_1350+47del microsatellite Tramadol response [RCV001029399] Chr7:87550124..87550125 [GRCh38]
Chr7:87179440..87179441 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1786G>C (p.Asp596His) single nucleotide variant Tramadol response [RCV001029422] Chr7:87545964 [GRCh38]
Chr7:87175280 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.2211+13C>T single nucleotide variant Tramadol response [RCV001029441] Chr7:87544116 [GRCh38]
Chr7:87173432 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.2211+22G>A single nucleotide variant Tramadol response [RCV001029444] Chr7:87544107 [GRCh38]
Chr7:87173423 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.2381G>A (p.Arg794Gln) single nucleotide variant Tramadol response [RCV001029457] Chr7:87539284 [GRCh38]
Chr7:87168600 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.2481+5G>A single nucleotide variant Tramadol response [RCV001029467] Chr7:87536453 [GRCh38]
Chr7:87165769 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.3084+23T>C single nucleotide variant Tramadol response [RCV001029483] Chr7:87516486 [GRCh38]
Chr7:87145802 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.3084+25G>T single nucleotide variant Tramadol response [RCV001029484] Chr7:87516484 [GRCh38]
Chr7:87145800 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.3283-61T>C single nucleotide variant Tramadol response [RCV001029492] Chr7:87509542 [GRCh38]
Chr7:87138858 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.3289del (p.Asp1097fs) deletion Tramadol response [RCV001029496] Chr7:87509475 [GRCh38]
Chr7:87138791 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.3370G>A (p.Asp1124Asn) single nucleotide variant Tramadol response [RCV001029501] Chr7:87509394 [GRCh38]
Chr7:87138710 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.3799T>G (p.Tyr1267Asp) single nucleotide variant Tramadol response [RCV001029515] Chr7:87504287 [GRCh38]
Chr7:87133603 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.3801T>A (p.Tyr1267Ter) single nucleotide variant Tramadol response [RCV001029517] Chr7:87504285 [GRCh38]
Chr7:87133601 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.2320-58T>G single nucleotide variant Tramadol response [RCV001029449] Chr7:87539403 [GRCh38]
Chr7:87168719 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.2397+23C>G single nucleotide variant Tramadol response [RCV001029459] Chr7:87539245 [GRCh38]
Chr7:87168561 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.2914G>A (p.Glu972Lys) single nucleotide variant Tramadol response [RCV001029476]|not specified [RCV004030902] Chr7:87519339 [GRCh38]
Chr7:87148655 [GRCh37]
Chr7:7q21.12		 drug response|uncertain significance
NM_001348946.2(ABCB1):c.2927+32T>A single nucleotide variant Tramadol response [RCV001029478] Chr7:87519294 [GRCh38]
Chr7:87148610 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.3282+27G>T single nucleotide variant Tramadol response [RCV001029489] Chr7:87515204 [GRCh38]
Chr7:87144520 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.3373T>A (p.Cys1125Ser) single nucleotide variant Tramadol response [RCV001029502] Chr7:87509391 [GRCh38]
Chr7:87138707 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.3749G>A (p.Arg1250Lys) single nucleotide variant Tramadol response [RCV001029513] Chr7:87504337 [GRCh38]
Chr7:87133653 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.3758A>G (p.Glu1253Gly) single nucleotide variant Tramadol response [RCV001029514] Chr7:87504328 [GRCh38]
Chr7:87133644 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.3800A>C (p.Tyr1267Ser) single nucleotide variant Tramadol response [RCV001029516] Chr7:87504286 [GRCh38]
Chr7:87133602 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.*13T>C single nucleotide variant Tramadol response [RCV001029519] Chr7:87504230 [GRCh38]
Chr7:87133546 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.*267T>C single nucleotide variant Tramadol response [RCV001029523] Chr7:87503976 [GRCh38]
Chr7:87133292 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.185G>T (p.Gly62Val) single nucleotide variant Tramadol response [RCV001029291] Chr7:87585613 [GRCh38]
Chr7:87214929 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.250A>C (p.Asn84His) single nucleotide variant Tramadol response [RCV001029295] Chr7:87585548 [GRCh38]
Chr7:87214864 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.286+34del deletion Tramadol response [RCV001029300] Chr7:87585478 [GRCh38]
Chr7:87214794 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.286+88C>A single nucleotide variant Tramadol response [RCV001029301] Chr7:87585424 [GRCh38]
Chr7:87214740 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.286+679T>C single nucleotide variant Tramadol response [RCV001029306] Chr7:87584833 [GRCh38]
Chr7:87214149 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.339-53G>T single nucleotide variant Tramadol response [RCV001029333] Chr7:87567029 [GRCh38]
Chr7:87196345 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.702+98C>T single nucleotide variant Tramadol response [RCV001029348] Chr7:87565972 [GRCh38]
Chr7:87195288 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.827+649A>C single nucleotide variant Tramadol response [RCV001029356] Chr7:87560614 [GRCh38]
Chr7:87189930 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.827+693G>C single nucleotide variant Tramadol response [RCV001029359] Chr7:87560570 [GRCh38]
Chr7:87189886 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.827+791A>G single nucleotide variant Tramadol response [RCV001029361] Chr7:87560472 [GRCh38]
Chr7:87189788 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.827+795C>T single nucleotide variant Tramadol response [RCV001029363] Chr7:87560468 [GRCh38]
Chr7:87189784 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1225-15C>T single nucleotide variant Tramadol response [RCV001029392] Chr7:87550311 [GRCh38]
Chr7:87179627 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1554+119T>A single nucleotide variant Tramadol response [RCV001029409] Chr7:87549732 [GRCh38]
Chr7:87179048 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1726-600T>G single nucleotide variant Tramadol response [RCV001029415] Chr7:87546624 [GRCh38]
Chr7:87175940 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.2211+21T>C single nucleotide variant Tramadol response [RCV001029443] Chr7:87544108 [GRCh38]
Chr7:87173424 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.2211+27T>C single nucleotide variant Tramadol response [RCV001029447] Chr7:87544102 [GRCh38]
Chr7:87173418 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.2320-51T>G single nucleotide variant Tramadol response [RCV001029450] Chr7:87539396 [GRCh38]
Chr7:87168712 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.2320-3C>G single nucleotide variant Tramadol response [RCV001029452] Chr7:87539348 [GRCh38]
Chr7:87168664 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.2481+13T>G single nucleotide variant Tramadol response [RCV001029469] Chr7:87536445 [GRCh38]
Chr7:87165761 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.2927+31C>T single nucleotide variant Tramadol response [RCV001029477] Chr7:87519295 [GRCh38]
Chr7:87148611 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.3085-62A>T single nucleotide variant Tramadol response [RCV001029488] Chr7:87515490 [GRCh38]
Chr7:87144806 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.3283-66G>A single nucleotide variant Tramadol response [RCV001029491] Chr7:87509547 [GRCh38]
Chr7:87138863 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.3283-54G>A single nucleotide variant Tramadol response [RCV001029493] Chr7:87509535 [GRCh38]
Chr7:87138851 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.3641T>G (p.Val1214Gly) single nucleotide variant Tramadol response [RCV001029506] Chr7:87504445 [GRCh38]
Chr7:87133761 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.3688A>G (p.Ile1230Val) single nucleotide variant Tramadol response [RCV001029510] Chr7:87504398 [GRCh38]
Chr7:87133714 [GRCh37]
Chr7:7q21.12		 drug response
NM_000927.5(ABCB1):c.-331+78T>A single nucleotide variant Tramadol response [RCV001028409] Chr7:87713083 [GRCh38]
Chr7:87342399 [GRCh37]
Chr7:7q21.12		 drug response
NM_000927.5(ABCB1):c.-281C>T single nucleotide variant Tramadol response [RCV001028419] Chr7:87601029 [GRCh38]
Chr7:87230345 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.98C>T (p.Thr33Ile) single nucleotide variant Tramadol response [RCV001028457] Chr7:87595785 [GRCh38]
Chr7:87225101 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.117+157T>C single nucleotide variant Tramadol response [RCV001028471] Chr7:87595609 [GRCh38]
Chr7:87224925 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.117+552C>A single nucleotide variant Tramadol response [RCV001028472] Chr7:87595214 [GRCh38]
Chr7:87224530 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.117+670A>G single nucleotide variant Tramadol response [RCV001028475] Chr7:87595096 [GRCh38]
Chr7:87224412 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.118-118T>G single nucleotide variant Tramadol response [RCV001028479] Chr7:87585798 [GRCh38]
Chr7:87215114 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.286+326T>C single nucleotide variant Tramadol response [RCV001028493] Chr7:87585186 [GRCh38]
Chr7:87214502 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.338+174C>A single nucleotide variant Tramadol response [RCV001028504] Chr7:87569998 [GRCh38]
Chr7:87199314 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.338+334G>A single nucleotide variant Tramadol response [RCV001028515] Chr7:87569838 [GRCh38]
Chr7:87199154 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.530+131del deletion Tramadol response [RCV001028530] Chr7:87566654 [GRCh38]
Chr7:87195970 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.530+213A>G single nucleotide variant Tramadol response [RCV001028533] Chr7:87566572 [GRCh38]
Chr7:87195888 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.703-1043T>A single nucleotide variant Tramadol response [RCV001028539] Chr7:87562430 [GRCh38]
Chr7:87191746 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.757G>A (p.Val253Ile) single nucleotide variant Tramadol response [RCV001028547] Chr7:87561333 [GRCh38]
Chr7:87190649 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.828-718A>G single nucleotide variant Tramadol response [RCV001028551] Chr7:87554650 [GRCh38]
Chr7:87183966 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.828-160del deletion Tramadol response [RCV001028560] Chr7:87554092 [GRCh38]
Chr7:87183408 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.828-82T>C single nucleotide variant Tramadol response [RCV001028564] Chr7:87554014 [GRCh38]
Chr7:87183330 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1021G>A (p.Gly341Arg) single nucleotide variant Tramadol response [RCV001028567] Chr7:87550817 [GRCh38]
Chr7:87180133 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1114-70G>A single nucleotide variant Tramadol response [RCV001028578] Chr7:87550648 [GRCh38]
Chr7:87179964 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1888-36C>T single nucleotide variant Tramadol response [RCV001028613] Chr7:87545035 [GRCh38]
Chr7:87174351 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.2064+21T>G single nucleotide variant Tramadol response [RCV001028619] Chr7:87544802 [GRCh38]
Chr7:87174118 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.2787-56C>T single nucleotide variant Tramadol response [RCV001028659] Chr7:87519522 [GRCh38]
Chr7:87148838 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.3201T>G (p.Ala1067=) single nucleotide variant Tramadol response [RCV001028669] Chr7:87515312 [GRCh38]
Chr7:87144628 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.3235G>A (p.Val1079Met) single nucleotide variant Tramadol response [RCV001028672] Chr7:87515278 [GRCh38]
Chr7:87144594 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.3490-66C>T single nucleotide variant Tramadol response [RCV001028679] Chr7:87506109 [GRCh38]
Chr7:87135425 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.3523C>T (p.Gln1175Ter) single nucleotide variant Tramadol response [RCV001028682] Chr7:87506010 [GRCh38]
Chr7:87135326 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.*161G>C single nucleotide variant Tramadol response [RCV001028701] Chr7:87504082 [GRCh38]
Chr7:87133398 [GRCh37]
Chr7:7q21.12		 drug response
NM_000927.5(ABCB1):c.-388T>G single nucleotide variant Tramadol response [RCV001029221] Chr7:87713218 [GRCh38]
Chr7:87342534 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.-6-74del deletion Tramadol response [RCV001029243] Chr7:87600264 [GRCh38]
Chr7:87229580 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.-6-44C>A single nucleotide variant Tramadol response [RCV001029244] Chr7:87600234 [GRCh38]
Chr7:87229550 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.-6-26G>C single nucleotide variant Tramadol response [RCV001029245] Chr7:87600216 [GRCh38]
Chr7:87229532 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.117+283T>A single nucleotide variant Tramadol response [RCV001029284] Chr7:87595483 [GRCh38]
Chr7:87224799 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.172del (p.Ala58fs) deletion Tramadol response [RCV001029290] Chr7:87585626 [GRCh38]
Chr7:87214942 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.193C>T (p.Leu65Phe) single nucleotide variant Tramadol response [RCV001029292] Chr7:87585605 [GRCh38]
Chr7:87214921 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.264G>A (p.Leu88=) single nucleotide variant Tramadol response [RCV001029296] Chr7:87585534 [GRCh38]
Chr7:87214850 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.302C>T (p.Thr101Ile) single nucleotide variant Tramadol response [RCV001029312] Chr7:87570208 [GRCh38]
Chr7:87199524 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.339-426del deletion Tramadol response [RCV001029322] Chr7:87567402 [GRCh38]
Chr7:87196718 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.339-363T>A single nucleotide variant Tramadol response [RCV001029327] Chr7:87567339 [GRCh38]
Chr7:87196655 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.339-315G>C single nucleotide variant Tramadol response [RCV001029329] Chr7:87567291 [GRCh38]
Chr7:87196607 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.702+239G>A single nucleotide variant Tramadol response [RCV001029349] Chr7:87565831 [GRCh38]
Chr7:87195147 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.827+655T>G single nucleotide variant Tramadol response [RCV001029358] Chr7:87560608 [GRCh38]
Chr7:87189924 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1000-47G>A single nucleotide variant Tramadol response [RCV001029379] Chr7:87550885 [GRCh38]
Chr7:87180201 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1225-41T>A single nucleotide variant Tramadol response [RCV001029391] Chr7:87550337 [GRCh38]
Chr7:87179653 [GRCh37]
Chr7:7q21.12		 drug response
NM_001348946.2(ABCB1):c.1554+81C>T single nucleotide variant Tramadol response [RCV001029408] Chr7:87549770 [GRCh38]
Chr7:87179086 [GRCh37]
Chr7:7q21.12		 drug response
Single allele complex Ring chromosome 7 [RCV002280646] Chr7:43360..159119707 [GRCh37]
Chr7:7p22.3-q36.3		 pathogenic
GRCh37/hg19 7q21.12(chr7:86907024-87154688)x1 copy number loss not provided [RCV001258805] Chr7:86907024..87154688 [GRCh37]
Chr7:7q21.12		 likely pathogenic
GRCh37/hg19 7q21.12(chr7:86833114-87553208)x3 copy number gain not provided [RCV001258806] Chr7:86833114..87553208 [GRCh37]
Chr7:7q21.12		 uncertain significance
NM_001348946.2(ABCB1):c.3044C>A (p.Thr1015Asn) single nucleotide variant not provided [RCV001356148] Chr7:87516549 [GRCh38]
Chr7:87145865 [GRCh37]
Chr7:7q21.12		 uncertain significance
NM_001348946.2(ABCB1):c.480A>G (p.Ile160Met) single nucleotide variant Inflammatory bowel disease 13 [RCV001335478] Chr7:87566835 [GRCh38]
Chr7:87196151 [GRCh37]
Chr7:7q21.12		 uncertain significance
NM_001348946.2(ABCB1):c.3412C>T (p.Arg1138Trp) single nucleotide variant Hereditary breast ovarian cancer syndrome [RCV001374561] Chr7:87509352 [GRCh38]
Chr7:87138668 [GRCh37]
Chr7:7q21.12		 uncertain significance
NM_001348946.2(ABCB1):c.470G>A (p.Arg157Gln) single nucleotide variant Inflammatory bowel disease 13 [RCV001334606] Chr7:87566845 [GRCh38]
Chr7:87196161 [GRCh37]
Chr7:7q21.12		 uncertain significance
NM_001348946.2(ABCB1):c.2678C>A (p.Ser893Tyr) single nucleotide variant Idiopathic generalized epilepsy [RCV001509550] Chr7:87531301 [GRCh38]
Chr7:87160617 [GRCh37]
Chr7:7q21.12		 likely pathogenic
GRCh37/hg19 7q21.11-21.3(chr7:77821356-93340137) copy number gain not specified [RCV002053701] Chr7:77821356..93340137 [GRCh37]
Chr7:7q21.11-21.3		 pathogenic
GRCh37/hg19 7p22.3-q36.3(chr7:56604613-96692931)x1 copy number loss See cases [RCV002287832] Chr7:56604613..96692931 [GRCh37]
Chr7:7p22.3-q36.3		 uncertain significance
NM_001348946.2(ABCB1):c.2006G>A (p.Arg669His) single nucleotide variant not specified [RCV004318862] Chr7:87544881 [GRCh38]
Chr7:87174197 [GRCh37]
Chr7:7q21.12		 uncertain significance
NM_001134405.2(RUNDC3B):c.455C>A (p.Thr152Asn) single nucleotide variant not specified [RCV004092651] Chr7:87710652 [GRCh38]
Chr7:87339968 [GRCh37]
Chr7:7q21.12		 uncertain significance
NM_001348946.2(ABCB1):c.56T>A (p.Leu19Gln) single nucleotide variant not specified [RCV004193203] Chr7:87600129 [GRCh38]
Chr7:87229445 [GRCh37]
Chr7:7q21.12		 uncertain significance
NM_001348946.2(ABCB1):c.1959G>T (p.Met653Ile) single nucleotide variant not specified [RCV004125194] Chr7:87544928 [GRCh38]
Chr7:87174244 [GRCh37]
Chr7:7q21.12		 uncertain significance
NM_001134405.2(RUNDC3B):c.43G>A (p.Gly15Ser) single nucleotide variant not specified [RCV004233840] Chr7:87628866 [GRCh38]
Chr7:87258182 [GRCh37]
Chr7:7q21.12		 uncertain significance
NM_001134405.2(RUNDC3B):c.40G>A (p.Gly14Ser) single nucleotide variant not specified [RCV004104272] Chr7:87628863 [GRCh38]
Chr7:87258179 [GRCh37]
Chr7:7q21.12		 uncertain significance
NM_001348946.2(ABCB1):c.2210G>A (p.Gly737Glu) single nucleotide variant not specified [RCV004166092] Chr7:87544130 [GRCh38]
Chr7:87173446 [GRCh37]
Chr7:7q21.12		 uncertain significance
NM_001348946.2(ABCB1):c.3769C>T (p.His1257Tyr) single nucleotide variant not specified [RCV004191321] Chr7:87504317 [GRCh38]
Chr7:87133633 [GRCh37]
Chr7:7q21.12		 uncertain significance
NM_001348946.2(ABCB1):c.2993A>C (p.Tyr998Ser) single nucleotide variant not specified [RCV004138250] Chr7:87516600 [GRCh38]
Chr7:87145916 [GRCh37]
Chr7:7q21.12		 uncertain significance
NM_001134405.2(RUNDC3B):c.329G>A (p.Cys110Tyr) single nucleotide variant not specified [RCV004177905] Chr7:87700511 [GRCh38]
Chr7:87329827 [GRCh37]
Chr7:7q21.12		 uncertain significance
NM_001348946.2(ABCB1):c.3247C>G (p.Leu1083Val) single nucleotide variant not specified [RCV004194316] Chr7:87515266 [GRCh38]
Chr7:87144582 [GRCh37]
Chr7:7q21.12		 uncertain significance
NM_001348946.2(ABCB1):c.2270T>C (p.Leu757Pro) single nucleotide variant not specified [RCV004160796] Chr7:87541406 [GRCh38]
Chr7:87170722 [GRCh37]
Chr7:7q21.12		 uncertain significance
NM_001348946.2(ABCB1):c.3066C>A (p.Ser1022Arg) single nucleotide variant not specified [RCV004156763] Chr7:87516527 [GRCh38]
Chr7:87145843 [GRCh37]
Chr7:7q21.12		 uncertain significance
NM_001134405.2(RUNDC3B):c.305G>A (p.Arg102Gln) single nucleotide variant not specified [RCV004155555] Chr7:87700487 [GRCh38]
Chr7:87329803 [GRCh37]
Chr7:7q21.12		 uncertain significance
NM_001134405.2(RUNDC3B):c.38G>C (p.Arg13Pro) single nucleotide variant not specified [RCV004167289] Chr7:87628861 [GRCh38]
Chr7:87258177 [GRCh37]
Chr7:7q21.12		 uncertain significance
NM_001348946.2(ABCB1):c.797C>T (p.Ala266Val) single nucleotide variant not specified [RCV004266737] Chr7:87561293 [GRCh38]
Chr7:87190609 [GRCh37]
Chr7:7q21.12		 uncertain significance
NM_001348946.2(ABCB1):c.3665G>C (p.Arg1222Thr) single nucleotide variant not specified [RCV004272885] Chr7:87504421 [GRCh38]
Chr7:87133737 [GRCh37]
Chr7:7q21.12		 uncertain significance
NM_001348946.2(ABCB1):c.2191A>G (p.Ile731Val) single nucleotide variant not specified [RCV004357895] Chr7:87544149 [GRCh38]
Chr7:87173465 [GRCh37]
Chr7:7q21.12		 uncertain significance
NM_001348946.2(ABCB1):c.1976G>A (p.Arg659Lys) single nucleotide variant not specified [RCV004358460] Chr7:87544911 [GRCh38]
Chr7:87174227 [GRCh37]
Chr7:7q21.12		 uncertain significance
NM_001348946.2(ABCB1):c.1225-34T>C single nucleotide variant not provided [RCV003433932] Chr7:87550330 [GRCh38]
Chr7:87179646 [GRCh37]
Chr7:7q21.12		 likely benign
NM_001348946.2(ABCB1):c.3826G>A (p.Gly1276Arg) single nucleotide variant not specified [RCV004415073] Chr7:87504260 [GRCh38]
Chr7:87133576 [GRCh37]
Chr7:7q21.12		 uncertain significance
NM_001348946.2(ABCB1):c.3385G>A (p.Glu1129Lys) single nucleotide variant not specified [RCV004414925] Chr7:87509379 [GRCh38]
Chr7:87138695 [GRCh37]
Chr7:7q21.12		 uncertain significance
NM_001348946.2(ABCB1):c.3835C>A (p.Arg1279Ser) single nucleotide variant not specified [RCV004415092] Chr7:87504251 [GRCh38]
Chr7:87133567 [GRCh37]
Chr7:7q21.12		 uncertain significance
NM_001348946.2(ABCB1):c.629G>A (p.Arg210His) single nucleotide variant not specified [RCV004415144] Chr7:87566143 [GRCh38]
Chr7:87195459 [GRCh37]
Chr7:7q21.12		 uncertain significance
NM_001134405.2(RUNDC3B):c.239-6464A>T single nucleotide variant not specified [RCV004447037] Chr7:87693957 [GRCh38]
Chr7:87323273 [GRCh37]
Chr7:7q21.12		 uncertain significance
NM_001348946.2(ABCB1):c.2397+8T>A single nucleotide variant ABCB1-related disorder [RCV003951450] Chr7:87539260 [GRCh38]
Chr7:87168576 [GRCh37]
Chr7:7q21.12		 likely benign
NM_001348946.2(ABCB1):c.3673C>T (p.Arg1225Cys) single nucleotide variant not specified [RCV004414987] Chr7:87504413 [GRCh38]
Chr7:87133729 [GRCh37]
Chr7:7q21.12		 uncertain significance
NM_001348946.2(ABCB1):c.3697C>T (p.Arg1233Cys) single nucleotide variant not specified [RCV004415026] Chr7:87504389 [GRCh38]
Chr7:87133705 [GRCh37]
Chr7:7q21.12		 uncertain significance
NM_001348946.2(ABCB1):c.702+9A>T single nucleotide variant ABCB1-related disorder [RCV003956778] Chr7:87566061 [GRCh38]
Chr7:87195377 [GRCh37]
Chr7:7q21.12		 likely benign
NM_001348946.2(ABCB1):c.-43A>G single nucleotide variant ABCB1-related disorder [RCV003981885] Chr7:87600791 [GRCh38]
Chr7:87230107 [GRCh37]
Chr7:7q21.12		 benign
NM_001348946.2(ABCB1):c.1984C>T (p.Leu662=) single nucleotide variant ABCB1-related disorder [RCV003914435] Chr7:87544903 [GRCh38]
Chr7:87174219 [GRCh37]
Chr7:7q21.12		 likely benign
NM_001348946.2(ABCB1):c.3768G>A (p.Thr1256=) single nucleotide variant ABCB1-related disorder [RCV003971713] Chr7:87504318 [GRCh38]
Chr7:87133634 [GRCh37]
Chr7:7q21.12		 likely benign
NM_001348946.2(ABCB1):c.612T>C (p.Phe204=) single nucleotide variant ABCB1-related disorder [RCV003926783] Chr7:87566160 [GRCh38]
Chr7:87195476 [GRCh37]
Chr7:7q21.12		 likely benign
NM_001348946.2(ABCB1):c.2786+9C>T single nucleotide variant ABCB1-related disorder [RCV003974131] Chr7:87520767 [GRCh38]
Chr7:87150083 [GRCh37]
Chr7:7q21.12		 likely benign
NM_001348946.2(ABCB1):c.1887+4T>G single nucleotide variant ABCB1-related disorder [RCV003952218] Chr7:87545859 [GRCh38]
Chr7:87175175 [GRCh37]
Chr7:7q21.12		 likely benign
NM_001348945.2(ABCB1):c.117G>A (p.Pro39=) single nucleotide variant ABCB1-related disorder [RCV003937123] Chr7:87600989 [GRCh38]
Chr7:87230305 [GRCh37]
Chr7:7q21.12		 likely benign
NM_001348946.2(ABCB1):c.338+5T>C single nucleotide variant ABCB1-related disorder [RCV003974264] Chr7:87570167 [GRCh38]
Chr7:87199483 [GRCh37]
Chr7:7q21.12		 likely benign
NM_001348946.2(ABCB1):c.3421T>A (p.Ser1141Thr) single nucleotide variant ABCB1-related disorder [RCV003921902] Chr7:87509343 [GRCh38]
Chr7:87138659 [GRCh37]
Chr7:7q21.12		 likely benign
NM_001348946.2(ABCB1):c.1589A>G (p.Gln530Arg) single nucleotide variant not specified [RCV004410307] Chr7:87549484 [GRCh38]
Chr7:87178800 [GRCh37]
Chr7:7q21.12		 uncertain significance
NM_001348946.2(ABCB1):c.1621A>G (p.Ile541Val) single nucleotide variant not specified [RCV004410324] Chr7:87549452 [GRCh38]
Chr7:87178768 [GRCh37]
Chr7:7q21.12		 uncertain significance
NM_001348946.2(ABCB1):c.1922C>G (p.Ala641Gly) single nucleotide variant not specified [RCV004412489] Chr7:87544965 [GRCh38]
Chr7:87174281 [GRCh37]
Chr7:7q21.12		 uncertain significance
NM_001348946.2(ABCB1):c.2257A>G (p.Asn753Asp) single nucleotide variant not specified [RCV004412654] Chr7:87541419 [GRCh38]
Chr7:87170735 [GRCh37]
Chr7:7q21.12		 uncertain significance
NM_001348946.2(ABCB1):c.230A>T (p.Asp77Val) single nucleotide variant not specified [RCV004412722] Chr7:87585568 [GRCh38]
Chr7:87214884 [GRCh37]
Chr7:7q21.12		 uncertain significance
NM_001348946.2(ABCB1):c.278C>T (p.Thr93Ile) single nucleotide variant not specified [RCV004412768] Chr7:87585520 [GRCh38]
Chr7:87214836 [GRCh37]
Chr7:7q21.12		 uncertain significance
NM_001348946.2(ABCB1):c.2443A>G (p.Thr815Ala) single nucleotide variant not specified [RCV004412742] Chr7:87536496 [GRCh38]
Chr7:87165812 [GRCh37]
Chr7:7q21.12		 uncertain significance
NM_001348946.2(ABCB1):c.3477G>T (p.Glu1159Asp) single nucleotide variant not specified [RCV004636949] Chr7:87509287 [GRCh38]
Chr7:87138603 [GRCh37]
Chr7:7q21.12		 uncertain significance
NM_001348946.2(ABCB1):c.1483G>A (p.Val495Ile) single nucleotide variant not specified [RCV004636987] Chr7:87549922 [GRCh38]
Chr7:87179238 [GRCh37]
Chr7:7q21.12		 uncertain significance
NM_001348946.2(ABCB1):c.1760A>G (p.His587Arg) single nucleotide variant not specified [RCV004644236] Chr7:87545990 [GRCh38]
Chr7:87175306 [GRCh37]
Chr7:7q21.12		 uncertain significance
NM_001348946.2(ABCB1):c.328G>A (p.Asp110Asn) single nucleotide variant not specified [RCV004644163] Chr7:87570182 [GRCh38]
Chr7:87199498 [GRCh37]
Chr7:7q21.12		 uncertain significance
NM_001348946.2(ABCB1):c.2756T>A (p.Met919Lys) single nucleotide variant not specified [RCV004631609] Chr7:87520806 [GRCh38]
Chr7:87150122 [GRCh37]
Chr7:7q21.12		 uncertain significance
NM_001348946.2(ABCB1):c.451T>C (p.Phe151Leu) single nucleotide variant not specified [RCV004637038] Chr7:87566864 [GRCh38]
Chr7:87196180 [GRCh37]
Chr7:7q21.12		 uncertain significance
NM_001348946.2(ABCB1):c.2546T>C (p.Ile849Thr) single nucleotide variant ABCB1-related disorder [RCV004732329] Chr7:87531433 [GRCh38]
Chr7:87160749 [GRCh37]
Chr7:7q21.12		 uncertain significance
NM_001348946.2(ABCB1):c.2380C>T (p.Arg794Ter) single nucleotide variant ENCEPHALOPATHY, ACUTE TRANSIENT [RCV004719024] Chr7:87539285 [GRCh38]
Chr7:87168601 [GRCh37]
Chr7:7q21.12		 pathogenic
NM_000927.4:c.3053-3056del deletion ENCEPHALOPATHY, ACUTE TRANSIENT [RCV004719025]   pathogenic
NM_001348946.2(ABCB1):c.2786+1G>T single nucleotide variant ENCEPHALOPATHY, ACUTE TRANSIENT [RCV004719026] Chr7:87520775 [GRCh38]
Chr7:87150091 [GRCh37]
Chr7:7q21.12		 pathogenic
ABCB1, GLN1182TER variation ENCEPHALOPATHY, ACUTE TRANSIENT [RCV004719027]   pathogenic
GRCh37/hg19 7q11.23-21.3(chr7:74666254-97791584)x1 copy number loss not provided [RCV004819352] Chr7:74666254..97791584 [GRCh37]
Chr7:7q11.23-21.3		 pathogenic
NM_001134405.2(RUNDC3B):c.79C>G (p.Arg27Gly) single nucleotide variant not specified [RCV004863306] Chr7:87628902 [GRCh38]
Chr7:87258218 [GRCh37]
Chr7:7q21.12		 uncertain significance
NM_001134405.2(RUNDC3B):c.98G>A (p.Arg33Lys) single nucleotide variant not specified [RCV004863310] Chr7:87628921 [GRCh38]
Chr7:87258237 [GRCh37]
Chr7:7q21.12		 uncertain significance
NM_001134405.2(RUNDC3B):c.205A>G (p.Ile69Val) single nucleotide variant not specified [RCV004863311] Chr7:87650904 [GRCh38]
Chr7:87280220 [GRCh37]
Chr7:7q21.12		 uncertain significance
NM_001348945.2(ABCB1):c.4A>T (p.Ser2Cys) single nucleotide variant Inflammatory bowel disease 13 [RCV004821354] Chr7:87602983 [GRCh38]
Chr7:87232299 [GRCh37]
Chr7:7q21.12		 uncertain significance
NM_001348946.2(ABCB1):c.3029T>C (p.Met1010Thr) single nucleotide variant not specified [RCV004934355] Chr7:87516564 [GRCh38]
Chr7:87145880 [GRCh37]
Chr7:7q21.12		 uncertain significance
NM_001348946.2(ABCB1):c.2017C>T (p.Arg673Cys) single nucleotide variant not specified [RCV004934225] Chr7:87544870 [GRCh38]
Chr7:87174186 [GRCh37]
Chr7:7q21.12		 uncertain significance
NM_001348946.2(ABCB1):c.1462A>T (p.Ile488Phe) single nucleotide variant not specified [RCV004934294] Chr7:87549943 [GRCh38]
Chr7:87179259 [GRCh37]
Chr7:7q21.12		 uncertain significance
NM_001348946.2(ABCB1):c.968C>T (p.Ser323Leu) single nucleotide variant not specified [RCV004934451] Chr7:87553792 [GRCh38]
Chr7:87183108 [GRCh37]
Chr7:7q21.12		 uncertain significance
NM_001348946.2(ABCB1):c.3259T>G (p.Tyr1087Asp) single nucleotide variant not specified [RCV004934159] Chr7:87515254 [GRCh38]
Chr7:87144570 [GRCh37]
Chr7:7q21.12		 uncertain significance
NM_001348946.2(ABCB1):c.3836G>A (p.Arg1279His) single nucleotide variant not specified [RCV004631389] Chr7:87504250 [GRCh38]
Chr7:87133566 [GRCh37]
Chr7:7q21.12		 uncertain significance
miRNA Target Status (No longer updated)

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
MIR298hsa-miR-298OncomiRDBexternal_infoNANA22521303
MIR451Ahsa-miR-451aMirtarbaseexternal_infoqRT-PCR//Luciferase reporter assay//Western blotFunctional MTI18645025

Predicted Target Of
Summary Value
Count of predictions:836
Count of miRNA genes:587
Interacting mature miRNAs:646
Transcripts:ENST00000265724, ENST00000416177, ENST00000475929, ENST00000476862, ENST00000482527, ENST00000483831, ENST00000488737, ENST00000491360, ENST00000496821, ENST00000543898
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
597422939GWAS1519013_Hserum alanine aminotransferase measurement QTL GWAS1519013 (human)1e-13serum alanine aminotransferase measurementserum alanine aminotransferase activity level (CMO:0000575)78755012787550128Human
597088631GWAS1184705_Hchemotherapy-induced alopecia, response to docetaxel trihydrate QTL GWAS1184705 (human)4e-08chemotherapy-induced alopecia, response to docetaxel trihydrate78757496387574964Human
597469341GWAS1565415_Hblood protein measurement QTL GWAS1565415 (human)6e-13blood protein amount (VT:0005416)blood protein measurement (CMO:0000028)78761564487615645Human
597446174GWAS1542248_Haspartate aminotransferase to alanine aminotransferase ratio QTL GWAS1542248 (human)2e-15aspartate aminotransferase to alanine aminotransferase ratioserum aspartate aminotransferase activity level to alanine aminotransferase activity level ratio (CMO:0002245)78755012787550128Human
597408760GWAS1504834_Hlaurylcarnitine measurement QTL GWAS1504834 (human)1e-11laurylcarnitine measurement78761091887610919Human
597081618GWAS1177692_Hcognitive decline measurement QTL GWAS1177692 (human)5e-08cognitive behavior trait (VT:0010450)78754378687543787Human
597288540GWAS1384614_Hphospholipids:total lipids ratio, high density lipoprotein cholesterol measurement QTL GWAS1384614 (human)1e-11phospholipids:total lipids ratio, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)78750360087503601Human
597160240GWAS1256314_Hlipid measurement QTL GWAS1256314 (human)0.000008lipid measurementblood lipid measurement (CMO:0000050)78768660687686607Human
597392124GWAS1488198_Hschizophrenia QTL GWAS1488198 (human)0.0000003schizophrenia78761564487615645Human
597392139GWAS1488213_Hage at menarche, spine bone mineral density QTL GWAS1488213 (human)0.0000008age at menarche, spine bone mineral densitybone mineral density (CMO:0001226)78763326587633266Human
597590381GWAS1647241_Hhyperpituitarism QTL GWAS1647241 (human)2e-12hyperpituitarism78751199487511995Human
597408815GWAS1504889_Hschizophrenia QTL GWAS1504889 (human)8e-10schizophrenia78761564487615645Human
597066880GWAS1162954_Hsusceptibility to chickenpox measurement QTL GWAS1162954 (human)0.000001susceptibility to chickenpox measurement78759016587590166Human
597105281GWAS1201355_Hcytokine measurement QTL GWAS1201355 (human)0.000002cytokine measurementblood cytokine measurement (CMO:0001924)78750919587509196Human
597392140GWAS1488214_Hage at menarche, spine bone mineral density QTL GWAS1488214 (human)0.000002age at menarche, spine bone mineral densitybone mineral density (CMO:0001226)78764118487641185Human
597208674GWAS1304748_Hcerebral microbleeds QTL GWAS1304748 (human)0.0000003cerebral microbleeds78757115187571152Human
597232386GWAS1328460_Halpha wave measurement QTL GWAS1328460 (human)0.000001alpha wave measurementbrain activity measurement (CMO:0001737)78754038687540387Human
597377728GWAS1473802_Hschizophrenia QTL GWAS1473802 (human)2e-09schizophrenia78761564487615645Human
597119051GWAS1215125_Happendicular lean mass QTL GWAS1215125 (human)3e-11appendicular lean mass78757322887573229Human
597384615GWAS1480689_Hschizophrenia QTL GWAS1480689 (human)2e-08schizophrenia78761564487615645Human

Markers in Region
PGY1  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37787,230,207 - 87,230,386UniSTSGRCh37
Build 36787,068,143 - 87,068,322RGDNCBI36
Celera781,935,077 - 81,935,256RGD
Cytogenetic Map7q21.12UniSTS
HuRef781,840,502 - 81,840,681UniSTS
CRA_TCAGchr7v2786,561,697 - 86,561,876UniSTS
RH17678  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37787,133,587 - 87,133,768UniSTSGRCh37
GRCh37787,031,440 - 87,031,621UniSTSGRCh37
Build 36786,869,376 - 86,869,557RGDNCBI36
Celera781,838,471 - 81,838,652UniSTS
Celera781,736,318 - 81,736,499RGD
Cytogenetic Map7q21.12UniSTS
Cytogenetic Map7q21.1UniSTS
HuRef781,642,436 - 81,642,617UniSTS
HuRef781,744,590 - 81,744,771UniSTS
CRA_TCAGchr7v2786,465,099 - 86,465,280UniSTS
CRA_TCAGchr7v2786,362,950 - 86,363,131UniSTS
GeneMap99-GB4 RH Map7474.18UniSTS
SHGC-83275  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37787,267,787 - 87,268,129UniSTSGRCh37
Build 36787,105,723 - 87,106,065RGDNCBI36
Celera781,972,401 - 81,972,743RGD
Cytogenetic Map7q21.12UniSTS
HuRef781,877,634 - 81,877,976UniSTS
CRA_TCAGchr7v2786,599,101 - 86,599,443UniSTS
TNG Radiation Hybrid Map737832.0UniSTS
G60182  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37787,133,254 - 87,133,446UniSTSGRCh37
Build 36786,971,190 - 86,971,382RGDNCBI36
Celera781,838,138 - 81,838,330RGD
Cytogenetic Map7q21.12UniSTS
HuRef781,744,257 - 81,744,449UniSTS
CRA_TCAGchr7v2786,464,766 - 86,464,958UniSTS
TNG Radiation Hybrid Map737892.0UniSTS
GDB:194851  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37787,174,297 - 87,174,606UniSTSGRCh37
Build 36787,012,233 - 87,012,542RGDNCBI36
Celera781,879,193 - 81,879,502RGD
Cytogenetic Map7q21.12UniSTS
HuRef781,785,312 - 81,785,621UniSTS
CRA_TCAGchr7v2786,505,813 - 86,506,122UniSTS
D7S2414  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37787,286,652 - 87,286,773UniSTSGRCh37
Build 36787,124,588 - 87,124,709RGDNCBI36
Celera781,991,267 - 81,991,388RGD
Cytogenetic Map7q21.12UniSTS
HuRef781,896,500 - 81,896,621UniSTS
CRA_TCAGchr7v2786,617,967 - 86,618,088UniSTS
SHGC-154970  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37787,140,991 - 87,141,263UniSTSGRCh37
Build 36786,978,927 - 86,979,199RGDNCBI36
Celera781,845,875 - 81,846,147RGD
Cytogenetic Map7q21.12UniSTS
HuRef781,751,993 - 81,752,265UniSTS
CRA_TCAGchr7v2786,472,503 - 86,472,775UniSTS
TNG Radiation Hybrid Map737869.0UniSTS
ABCB1_2602  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37787,133,036 - 87,133,832UniSTSGRCh37
Build 36786,970,972 - 86,971,768RGDNCBI36
Celera781,837,920 - 81,838,716RGD
HuRef781,744,039 - 81,744,835UniSTS
CRA_TCAGchr7v2786,464,548 - 86,465,344UniSTS
GDB:1317232  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37787,243,095 - 87,243,229UniSTSGRCh37
Build 36787,081,031 - 87,081,165RGDNCBI36
Celera781,947,963 - 81,948,097RGD
Cytogenetic Map7q21.12UniSTS
CRA_TCAGchr7v2786,574,585 - 86,574,719UniSTS
GDB:1317328  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37787,228,250 - 87,228,332UniSTSGRCh37
Build 36787,066,186 - 87,066,268RGDNCBI36
Celera781,933,120 - 81,933,202RGD
Cytogenetic Map7q21.12UniSTS
HuRef781,838,545 - 81,838,627UniSTS
CRA_TCAGchr7v2786,559,740 - 86,559,822UniSTS
SHGC-56130  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37787,133,249 - 87,133,500UniSTSGRCh37
Build 36786,971,185 - 86,971,436RGDNCBI36
Celera781,838,133 - 81,838,384RGD
Cytogenetic Map7q21.12UniSTS
HuRef781,744,252 - 81,744,503UniSTS
CRA_TCAGchr7v2786,464,761 - 86,465,012UniSTS
GeneMap99-GB4 RH Map7474.08UniSTS
Whitehead-RH Map7448.5UniSTS
GDB:6028578  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37787,342,477 - 87,342,728UniSTSGRCh37
Build 36787,180,413 - 87,180,664RGDNCBI36
Celera782,047,089 - 82,047,340RGD
Cytogenetic Map7q21.12UniSTS
HuRef781,952,416 - 81,952,667UniSTS
CRA_TCAGchr7v2786,673,791 - 86,674,042UniSTS
D7S2326  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37787,133,203 - 87,133,510UniSTSGRCh37
Build 36786,971,139 - 86,971,446RGDNCBI36
Celera781,838,087 - 81,838,394RGD
Cytogenetic Map7q21.12UniSTS
HuRef781,744,206 - 81,744,513UniSTS
CRA_TCAGchr7v2786,464,715 - 86,465,022UniSTS
GeneMap99-GB4 RH Map7475.45UniSTS
Whitehead-RH Map7448.7UniSTS
Whitehead-YAC Contig Map7 UniSTS


Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
pharyngeal arch
renal system
reproductive system
respiratory system
sensory system
visual system
1204 2401 2786 2238 4935 1719 2255 3 621 1881 463 2257 7210 6395 30 3708 1 839 1711 1527 171 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NG_011513 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_000927 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001348944 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001348945 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001348946 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AA776371 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB208970 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC002457 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC005068 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF016534 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF016535 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF345623 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF345624 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF345625 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF345626 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH002875 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH003342 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK290159 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK308467 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY425005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY425006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY425007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY452673 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY490254 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY910577 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC130424 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BQ720763 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BQ882401 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX509020 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB164676 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH236949 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471091 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068271 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU852583 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU854148 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FJ158815 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291569 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291570 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291571 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291572 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291573 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291574 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291575 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291576 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291577 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291578 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291579 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291580 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291581 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291582 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291583 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291584 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291585 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291586 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291587 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291588 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291589 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291590 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291591 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291592 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291593 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291594 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291595 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291596 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291597 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291598 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291599 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291600 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291601 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291602 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291603 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291604 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291605 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291606 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291607 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291608 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291609 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291610 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291611 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291612 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291613 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291614 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291615 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291616 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291617 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291618 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291619 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291620 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291621 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291622 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291623 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291624 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291625 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291626 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291627 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291628 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291629 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291630 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291631 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291632 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291633 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291634 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291635 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291636 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291637 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291638 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291639 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291640 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291641 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291642 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291643 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291644 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291645 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291646 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291647 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291648 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291649 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291650 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291651 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291652 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291653 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291654 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291655 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291656 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291657 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291658 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291659 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291660 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291661 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291662 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291663 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291664 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291665 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291666 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291667 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291668 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291669 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291670 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291671 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291672 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291673 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291674 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291675 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291676 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291677 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291678 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291679 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291680 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291681 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291682 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291683 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291684 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291685 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291686 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291687 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291688 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291689 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291690 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291691 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291692 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291693 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291694 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291695 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291696 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291697 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291698 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291699 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291700 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291701 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291702 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291703 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291704 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291705 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291706 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291707 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291708 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291709 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291710 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291711 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291712 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291713 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291714 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291715 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291716 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291717 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291718 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291719 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291720 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291721 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291722 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291723 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291724 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291725 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291726 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291727 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291728 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291729 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291730 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291731 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291732 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291733 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291734 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291735 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291736 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291737 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291738 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291739 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291740 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291741 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291742 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291743 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291744 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291745 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291746 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291747 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291748 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291749 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291750 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291751 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291752 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291753 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291754 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291755 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291756 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291757 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291758 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291760 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291761 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291762 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291763 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291764 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ291765 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L07624 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M14758 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M57450 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  OK480632 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  OK480633 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X58723 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENST00000265724   ⟹   ENSP00000265724
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl787,503,859 - 87,713,323 (-)Ensembl
Ensembl Acc Id: ENST00000416177   ⟹   ENSP00000399419
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl787,585,654 - 87,713,294 (-)Ensembl
Ensembl Acc Id: ENST00000475929
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl787,505,902 - 87,518,963 (-)Ensembl
Ensembl Acc Id: ENST00000476862
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl787,600,813 - 87,713,295 (-)Ensembl
Ensembl Acc Id: ENST00000482527
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl787,545,949 - 87,550,158 (-)Ensembl
Ensembl Acc Id: ENST00000483831
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl787,516,509 - 87,521,119 (-)Ensembl
Ensembl Acc Id: ENST00000488737
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl787,503,864 - 87,531,697 (-)Ensembl
Ensembl Acc Id: ENST00000491360
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl787,504,156 - 87,506,141 (-)Ensembl
Ensembl Acc Id: ENST00000496821
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl787,515,228 - 87,537,062 (-)Ensembl
Ensembl Acc Id: ENST00000543898   ⟹   ENSP00000444095
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl787,503,863 - 87,713,323 (-)Ensembl
Ensembl Acc Id: ENST00000622132   ⟹   ENSP00000478255
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl787,503,017 - 87,600,884 (-)Ensembl
RefSeq Acc Id: NM_000927   ⟹   NP_000918
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38787,503,017 - 87,713,295 (-)NCBI
GRCh37787,133,179 - 87,342,639 (-)ENTREZGENE
Build 36786,970,884 - 87,180,500 (-)NCBI Archive
HuRef781,744,182 - 81,952,578 (-)ENTREZGENE
CHM1_1787,063,281 - 87,272,756 (-)NCBI
T2T-CHM13v2.0788,752,787 - 88,963,178 (-)NCBI
CRA_TCAGchr7v2786,464,691 - 86,673,953 (-)ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001348944   ⟹   NP_001335873
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38787,503,017 - 87,713,295 (-)NCBI
T2T-CHM13v2.0788,752,787 - 88,963,178 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001348945   ⟹   NP_001335874
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38787,503,017 - 87,713,295 (-)NCBI
T2T-CHM13v2.0788,752,787 - 88,963,178 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001348946   ⟹   NP_001335875
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38787,503,017 - 87,600,884 (-)NCBI
T2T-CHM13v2.0788,752,787 - 88,850,672 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_000918 (Get FASTA)   NCBI Sequence Viewer  
  NP_001335873 (Get FASTA)   NCBI Sequence Viewer  
  NP_001335874 (Get FASTA)   NCBI Sequence Viewer  
  NP_001335875 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA59575 (Get FASTA)   NCBI Sequence Viewer  
  AAA59576 (Get FASTA)   NCBI Sequence Viewer  
  AAA88047 (Get FASTA)   NCBI Sequence Viewer  
  AAA88048 (Get FASTA)   NCBI Sequence Viewer  
  AAB69423 (Get FASTA)   NCBI Sequence Viewer  
  AAB70218 (Get FASTA)   NCBI Sequence Viewer  
  AAI30425 (Get FASTA)   NCBI Sequence Viewer  
  AAM49149 (Get FASTA)   NCBI Sequence Viewer  
  AAR83914 (Get FASTA)   NCBI Sequence Viewer  
  AAR91621 (Get FASTA)   NCBI Sequence Viewer  
  AAR91622 (Get FASTA)   NCBI Sequence Viewer  
  AAR99172 (Get FASTA)   NCBI Sequence Viewer  
  AAW82430 (Get FASTA)   NCBI Sequence Viewer  
  ACF94687 (Get FASTA)   NCBI Sequence Viewer  
  ACF94688 (Get FASTA)   NCBI Sequence Viewer  
  ACH96452 (Get FASTA)   NCBI Sequence Viewer  
  AEC13104 (Get FASTA)   NCBI Sequence Viewer  
  AEC13105 (Get FASTA)   NCBI Sequence Viewer  
  AEC13106 (Get FASTA)   NCBI Sequence Viewer  
  AEC13107 (Get FASTA)   NCBI Sequence Viewer  
  AEC13108 (Get FASTA)   NCBI Sequence Viewer  
  AEC13109 (Get FASTA)   NCBI Sequence Viewer  
  AEC13110 (Get FASTA)   NCBI Sequence Viewer  
  AEC13111 (Get FASTA)   NCBI Sequence Viewer  
  AEC13112 (Get FASTA)   NCBI Sequence Viewer  
  AEC13113 (Get FASTA)   NCBI Sequence Viewer  
  AEC13114 (Get FASTA)   NCBI Sequence Viewer  
  AEC13115 (Get FASTA)   NCBI Sequence Viewer  
  AEC13116 (Get FASTA)   NCBI Sequence Viewer  
  AEC13117 (Get FASTA)   NCBI Sequence Viewer  
  AEC13118 (Get FASTA)   NCBI Sequence Viewer  
  AEC13119 (Get FASTA)   NCBI Sequence Viewer  
  AEC13120 (Get FASTA)   NCBI Sequence Viewer  
  AEC13121 (Get FASTA)   NCBI Sequence Viewer  
  AEC13122 (Get FASTA)   NCBI Sequence Viewer  
  AEC13123 (Get FASTA)   NCBI Sequence Viewer  
  AEC13124 (Get FASTA)   NCBI Sequence Viewer  
  AEC13125 (Get FASTA)   NCBI Sequence Viewer  
  AEC13126 (Get FASTA)   NCBI Sequence Viewer  
  AEC13127 (Get FASTA)   NCBI Sequence Viewer  
  AEC13128 (Get FASTA)   NCBI Sequence Viewer  
  AEC13129 (Get FASTA)   NCBI Sequence Viewer  
  AEC13130 (Get FASTA)   NCBI Sequence Viewer  
  AEC13131 (Get FASTA)   NCBI Sequence Viewer  
  AEC13132 (Get FASTA)   NCBI Sequence Viewer  
  AEC13133 (Get FASTA)   NCBI Sequence Viewer  
  AEC13134 (Get FASTA)   NCBI Sequence Viewer  
  AEC13135 (Get FASTA)   NCBI Sequence Viewer  
  AEC13136 (Get FASTA)   NCBI Sequence Viewer  
  AEC13137 (Get FASTA)   NCBI Sequence Viewer  
  AEC13138 (Get FASTA)   NCBI Sequence Viewer  
  AEC13139 (Get FASTA)   NCBI Sequence Viewer  
  AEC13140 (Get FASTA)   NCBI Sequence Viewer  
  AEC13141 (Get FASTA)   NCBI Sequence Viewer  
  AEC13142 (Get FASTA)   NCBI Sequence Viewer  
  AEC13143 (Get FASTA)   NCBI Sequence Viewer  
  AEC13144 (Get FASTA)   NCBI Sequence Viewer  
  AEC13145 (Get FASTA)   NCBI Sequence Viewer  
  AEC13146 (Get FASTA)   NCBI Sequence Viewer  
  AEC13147 (Get FASTA)   NCBI Sequence Viewer  
  AEC13148 (Get FASTA)   NCBI Sequence Viewer  
  AEC13149 (Get FASTA)   NCBI Sequence Viewer  
  AEC13150 (Get FASTA)   NCBI Sequence Viewer  
  AEC13151 (Get FASTA)   NCBI Sequence Viewer  
  AEC13152 (Get FASTA)   NCBI Sequence Viewer  
  AEC13153 (Get FASTA)   NCBI Sequence Viewer  
  AEC13154 (Get FASTA)   NCBI Sequence Viewer  
  AEC13155 (Get FASTA)   NCBI Sequence Viewer  
  AEC13156 (Get FASTA)   NCBI Sequence Viewer  
  AEC13157 (Get FASTA)   NCBI Sequence Viewer  
  AEC13158 (Get FASTA)   NCBI Sequence Viewer  
  AEC13159 (Get FASTA)   NCBI Sequence Viewer  
  AEC13160 (Get FASTA)   NCBI Sequence Viewer  
  AEC13161 (Get FASTA)   NCBI Sequence Viewer  
  AEC13162 (Get FASTA)   NCBI Sequence Viewer  
  AEC13163 (Get FASTA)   NCBI Sequence Viewer  
  AEC13164 (Get FASTA)   NCBI Sequence Viewer  
  AEC13165 (Get FASTA)   NCBI Sequence Viewer  
  AEC13166 (Get FASTA)   NCBI Sequence Viewer  
  AEC13167 (Get FASTA)   NCBI Sequence Viewer  
  AEC13168 (Get FASTA)   NCBI Sequence Viewer  
  AEC13169 (Get FASTA)   NCBI Sequence Viewer  
  AEC13170 (Get FASTA)   NCBI Sequence Viewer  
  AEC13171 (Get FASTA)   NCBI Sequence Viewer  
  AEC13172 (Get FASTA)   NCBI Sequence Viewer  
  AEC13173 (Get FASTA)   NCBI Sequence Viewer  
  AEC13174 (Get FASTA)   NCBI Sequence Viewer  
  AEC13175 (Get FASTA)   NCBI Sequence Viewer  
  AEC13176 (Get FASTA)   NCBI Sequence Viewer  
  AEC13177 (Get FASTA)   NCBI Sequence Viewer  
  AEC13178 (Get FASTA)   NCBI Sequence Viewer  
  AEC13179 (Get FASTA)   NCBI Sequence Viewer  
  AEC13180 (Get FASTA)   NCBI Sequence Viewer  
  AEC13181 (Get FASTA)   NCBI Sequence Viewer  
  AEC13182 (Get FASTA)   NCBI Sequence Viewer  
  AEC13183 (Get FASTA)   NCBI Sequence Viewer  
  AEC13184 (Get FASTA)   NCBI Sequence Viewer  
  AEC13185 (Get FASTA)   NCBI Sequence Viewer  
  AEC13186 (Get FASTA)   NCBI Sequence Viewer  
  AEC13187 (Get FASTA)   NCBI Sequence Viewer  
  AEC13188 (Get FASTA)   NCBI Sequence Viewer  
  AEC13189 (Get FASTA)   NCBI Sequence Viewer  
  AEC13190 (Get FASTA)   NCBI Sequence Viewer  
  AEC13191 (Get FASTA)   NCBI Sequence Viewer  
  AEC13192 (Get FASTA)   NCBI Sequence Viewer  
  AEC13193 (Get FASTA)   NCBI Sequence Viewer  
  AEC13194 (Get FASTA)   NCBI Sequence Viewer  
  AEC13195 (Get FASTA)   NCBI Sequence Viewer  
  AEC13196 (Get FASTA)   NCBI Sequence Viewer  
  AEC13197 (Get FASTA)   NCBI Sequence Viewer  
  AEC13198 (Get FASTA)   NCBI Sequence Viewer  
  AEC13199 (Get FASTA)   NCBI Sequence Viewer  
  AEC13200 (Get FASTA)   NCBI Sequence Viewer  
  AEC13201 (Get FASTA)   NCBI Sequence Viewer  
  AEC13202 (Get FASTA)   NCBI Sequence Viewer  
  AEC13203 (Get FASTA)   NCBI Sequence Viewer  
  AEC13204 (Get FASTA)   NCBI Sequence Viewer  
  AEC13205 (Get FASTA)   NCBI Sequence Viewer  
  AEC13206 (Get FASTA)   NCBI Sequence Viewer  
  AEC13207 (Get FASTA)   NCBI Sequence Viewer  
  AEC13208 (Get FASTA)   NCBI Sequence Viewer  
  AEC13209 (Get FASTA)   NCBI Sequence Viewer  
  AEC13210 (Get FASTA)   NCBI Sequence Viewer  
  AEC13211 (Get FASTA)   NCBI Sequence Viewer  
  AEC13212 (Get FASTA)   NCBI Sequence Viewer  
  AEC13213 (Get FASTA)   NCBI Sequence Viewer  
  AEC13214 (Get FASTA)   NCBI Sequence Viewer  
  AEC13215 (Get FASTA)   NCBI Sequence Viewer  
  AEC13216 (Get FASTA)   NCBI Sequence Viewer  
  AEC13217 (Get FASTA)   NCBI Sequence Viewer  
  AEC13218 (Get FASTA)   NCBI Sequence Viewer  
  AEC13219 (Get FASTA)   NCBI Sequence Viewer  
  AEC13220 (Get FASTA)   NCBI Sequence Viewer  
  AEC13221 (Get FASTA)   NCBI Sequence Viewer  
  AEC13222 (Get FASTA)   NCBI Sequence Viewer  
  AEC13223 (Get FASTA)   NCBI Sequence Viewer  
  AEC13224 (Get FASTA)   NCBI Sequence Viewer  
  AEC13225 (Get FASTA)   NCBI Sequence Viewer  
  AEC13226 (Get FASTA)   NCBI Sequence Viewer  
  AEC13227 (Get FASTA)   NCBI Sequence Viewer  
  AEC13228 (Get FASTA)   NCBI Sequence Viewer  
  AEC13229 (Get FASTA)   NCBI Sequence Viewer  
  AEC13230 (Get FASTA)   NCBI Sequence Viewer  
  AEC13231 (Get FASTA)   NCBI Sequence Viewer  
  AEC13232 (Get FASTA)   NCBI Sequence Viewer  
  AEC13233 (Get FASTA)   NCBI Sequence Viewer  
  AEC13234 (Get FASTA)   NCBI Sequence Viewer  
  AEC13235 (Get FASTA)   NCBI Sequence Viewer  
  AEC13236 (Get FASTA)   NCBI Sequence Viewer  
  AEC13237 (Get FASTA)   NCBI Sequence Viewer  
  AEC13238 (Get FASTA)   NCBI Sequence Viewer  
  AEC13239 (Get FASTA)   NCBI Sequence Viewer  
  AEC13240 (Get FASTA)   NCBI Sequence Viewer  
  AEC13241 (Get FASTA)   NCBI Sequence Viewer  
  AEC13242 (Get FASTA)   NCBI Sequence Viewer  
  AEC13243 (Get FASTA)   NCBI Sequence Viewer  
  AEC13244 (Get FASTA)   NCBI Sequence Viewer  
  AEC13245 (Get FASTA)   NCBI Sequence Viewer  
  AEC13246 (Get FASTA)   NCBI Sequence Viewer  
  AEC13247 (Get FASTA)   NCBI Sequence Viewer  
  AEC13248 (Get FASTA)   NCBI Sequence Viewer  
  AEC13249 (Get FASTA)   NCBI Sequence Viewer  
  AEC13250 (Get FASTA)   NCBI Sequence Viewer  
  AEC13251 (Get FASTA)   NCBI Sequence Viewer  
  AEC13252 (Get FASTA)   NCBI Sequence Viewer  
  AEC13253 (Get FASTA)   NCBI Sequence Viewer  
  AEC13254 (Get FASTA)   NCBI Sequence Viewer  
  AEC13255 (Get FASTA)   NCBI Sequence Viewer  
  AEC13256 (Get FASTA)   NCBI Sequence Viewer  
  AEC13257 (Get FASTA)   NCBI Sequence Viewer  
  AEC13258 (Get FASTA)   NCBI Sequence Viewer  
  AEC13259 (Get FASTA)   NCBI Sequence Viewer  
  AEC13260 (Get FASTA)   NCBI Sequence Viewer  
  AEC13261 (Get FASTA)   NCBI Sequence Viewer  
  AEC13262 (Get FASTA)   NCBI Sequence Viewer  
  AEC13263 (Get FASTA)   NCBI Sequence Viewer  
  AEC13264 (Get FASTA)   NCBI Sequence Viewer  
  AEC13265 (Get FASTA)   NCBI Sequence Viewer  
  AEC13266 (Get FASTA)   NCBI Sequence Viewer  
  AEC13267 (Get FASTA)   NCBI Sequence Viewer  
  AEC13268 (Get FASTA)   NCBI Sequence Viewer  
  AEC13269 (Get FASTA)   NCBI Sequence Viewer  
  AEC13270 (Get FASTA)   NCBI Sequence Viewer  
  AEC13271 (Get FASTA)   NCBI Sequence Viewer  
  AEC13272 (Get FASTA)   NCBI Sequence Viewer  
  AEC13273 (Get FASTA)   NCBI Sequence Viewer  
  AEC13274 (Get FASTA)   NCBI Sequence Viewer  
  AEC13275 (Get FASTA)   NCBI Sequence Viewer  
  AEC13276 (Get FASTA)   NCBI Sequence Viewer  
  AEC13277 (Get FASTA)   NCBI Sequence Viewer  
  AEC13278 (Get FASTA)   NCBI Sequence Viewer  
  AEC13279 (Get FASTA)   NCBI Sequence Viewer  
  AEC13280 (Get FASTA)   NCBI Sequence Viewer  
  AEC13281 (Get FASTA)   NCBI Sequence Viewer  
  AEC13282 (Get FASTA)   NCBI Sequence Viewer  
  AEC13283 (Get FASTA)   NCBI Sequence Viewer  
  AEC13284 (Get FASTA)   NCBI Sequence Viewer  
  AEC13285 (Get FASTA)   NCBI Sequence Viewer  
  AEC13286 (Get FASTA)   NCBI Sequence Viewer  
  AEC13287 (Get FASTA)   NCBI Sequence Viewer  
  AEC13288 (Get FASTA)   NCBI Sequence Viewer  
  AEC13289 (Get FASTA)   NCBI Sequence Viewer  
  AEC13290 (Get FASTA)   NCBI Sequence Viewer  
  AEC13291 (Get FASTA)   NCBI Sequence Viewer  
  AEC13292 (Get FASTA)   NCBI Sequence Viewer  
  AEC13293 (Get FASTA)   NCBI Sequence Viewer  
  AEC13295 (Get FASTA)   NCBI Sequence Viewer  
  AEC13296 (Get FASTA)   NCBI Sequence Viewer  
  AEC13297 (Get FASTA)   NCBI Sequence Viewer  
  AEC13298 (Get FASTA)   NCBI Sequence Viewer  
  AEC13299 (Get FASTA)   NCBI Sequence Viewer  
  AEC13300 (Get FASTA)   NCBI Sequence Viewer  
  BAD92207 (Get FASTA)   NCBI Sequence Viewer  
  BAF82848 (Get FASTA)   NCBI Sequence Viewer  
  CAA41558 (Get FASTA)   NCBI Sequence Viewer  
  EAL24173 (Get FASTA)   NCBI Sequence Viewer  
  EAW76940 (Get FASTA)   NCBI Sequence Viewer  
  EAW76941 (Get FASTA)   NCBI Sequence Viewer  
  EAW76942 (Get FASTA)   NCBI Sequence Viewer  
  EAW76943 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSP00000265724
  ENSP00000265724.3
  ENSP00000399419.1
  ENSP00000444095.1
  ENSP00000478255
  ENSP00000478255.1
GenBank Protein P08183 (Get FASTA)   NCBI Sequence Viewer  
  UDL17972 (Get FASTA)   NCBI Sequence Viewer  
  UDL17973 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_000918   ⟸   NM_000927
- Peptide Label: isoform 2
- UniProtKB: Q12755 (UniProtKB/Swiss-Prot),   B5AK60 (UniProtKB/Swiss-Prot),   A8K294 (UniProtKB/Swiss-Prot),   Q14812 (UniProtKB/Swiss-Prot),   P08183 (UniProtKB/Swiss-Prot),   A4D1D2 (UniProtKB/TrEMBL),   A1L471 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001335873   ⟸   NM_001348944
- Peptide Label: isoform 2
- UniProtKB: Q12755 (UniProtKB/Swiss-Prot),   P08183 (UniProtKB/Swiss-Prot),   B5AK60 (UniProtKB/Swiss-Prot),   A8K294 (UniProtKB/Swiss-Prot),   Q14812 (UniProtKB/Swiss-Prot),   A4D1D2 (UniProtKB/TrEMBL),   A1L471 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001335874   ⟸   NM_001348945
- Peptide Label: isoform 1
- UniProtKB: A1L471 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001335875   ⟸   NM_001348946
- Peptide Label: isoform 2
- UniProtKB: Q12755 (UniProtKB/Swiss-Prot),   P08183 (UniProtKB/Swiss-Prot),   B5AK60 (UniProtKB/Swiss-Prot),   A8K294 (UniProtKB/Swiss-Prot),   Q14812 (UniProtKB/Swiss-Prot),   A4D1D2 (UniProtKB/TrEMBL),   A1L471 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSP00000444095   ⟸   ENST00000543898
Ensembl Acc Id: ENSP00000478255   ⟸   ENST00000622132
Ensembl Acc Id: ENSP00000399419   ⟸   ENST00000416177
Ensembl Acc Id: ENSP00000265724   ⟸   ENST00000265724
Protein Domains
ABC transmembrane type-1   ABC transporter

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P08183-F1-model_v2 AlphaFold P08183 1-1280 view protein structure

Promoters
RGD ID:6805057
Promoter ID:HG_KWN:58441
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   Lymphoblastoid
Transcripts:OTTHUMT00000335445
Position:
Human AssemblyChrPosition (strand)Source
Build 36787,067,526 - 87,068,192 (-)MPROMDB
RGD ID:6849690
Promoter ID:EP35012
Type:single initiation site
Name:HS_ABCB1
Description:P-glycoprotein 1.
SO ACC ID:SO:0000170
Source:EPD (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Notes:homology_group=Homology group 199; Mammalian P-glycoprotein 1a.
Tissues & Cell Lines:ubiquitous, strong in liver, kidney
Experiment Methods:Nuclease protection; Primer extension; Primer extension; transfected or transformed cells
Position:
Human AssemblyChrPosition (strand)Source
Build 36787,068,139 - 87,068,199EPD
RGD ID:7210979
Promoter ID:EPDNEW_H11235
Type:multiple initiation site
Name:ABCB1_1
Description:ATP binding cassette subfamily B member 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H11237  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38787,600,884 - 87,600,944EPDNEW
RGD ID:7210981
Promoter ID:EPDNEW_H11237
Type:initiation region
Name:ABCB1_2
Description:ATP binding cassette subfamily B member 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H11235  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38787,713,295 - 87,713,355EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:40 AgrOrtholog
COSMIC ABCB1 COSMIC
Ensembl Genes ENSG00000085563 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000265724 ENTREZGENE
  ENST00000265724.8 UniProtKB/Swiss-Prot
  ENST00000416177.1 UniProtKB/TrEMBL
  ENST00000543898.5 UniProtKB/Swiss-Prot
  ENST00000622132 ENTREZGENE
  ENST00000622132.5 UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.1560.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000085563 GTEx
HGNC ID HGNC:40 ENTREZGENE
Human Proteome Map ABCB1 Human Proteome Map
InterPro AAA+_ATPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ABC1_TM_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ABC1_TM_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ABC_transporter-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ABC_transporter_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Type_I_exporter UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:5243 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 5243 ENTREZGENE
OMIM 171050 OMIM
PANTHER ATP-BINDING CASSETTE SUBFAMILY B MEMBER 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ATP-DEPENDENT PERMEASE MDL1, MITOCHONDRIAL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR24221 UniProtKB/TrEMBL
  PTHR24221:SF251 UniProtKB/TrEMBL
Pfam ABC_membrane UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ABC_tran UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB ABCB1 RGD, PharmGKB
PROSITE ABC_TM1F UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ABC_TRANSPORTER_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ABC_TRANSPORTER_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART AAA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF90123 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A1L471 ENTREZGENE, UniProtKB/TrEMBL
  A4D1D2 ENTREZGENE, UniProtKB/TrEMBL
  A8E2S6_HUMAN UniProtKB/TrEMBL
  A8K294 ENTREZGENE
  B5AK60 ENTREZGENE
  B5U2G4_HUMAN UniProtKB/TrEMBL
  E7EWT8_HUMAN UniProtKB/TrEMBL
  F4ZUQ5_HUMAN UniProtKB/TrEMBL
  F4ZUT2_HUMAN UniProtKB/TrEMBL
  F4ZUV0_HUMAN UniProtKB/TrEMBL
  F4ZUV4_HUMAN UniProtKB/TrEMBL
  F4ZUX9_HUMAN UniProtKB/TrEMBL
  F4ZUY5_HUMAN UniProtKB/TrEMBL
  F4ZV79_HUMAN UniProtKB/TrEMBL
  MDR1_HUMAN UniProtKB/Swiss-Prot, ENTREZGENE
  Q12755 ENTREZGENE
  Q14812 ENTREZGENE
  Q6TBL4_HUMAN UniProtKB/TrEMBL
UniProt Secondary A8K294 UniProtKB/Swiss-Prot
  B5AK60 UniProtKB/Swiss-Prot
  Q12755 UniProtKB/Swiss-Prot
  Q14812 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-11-24 ABCB1  ATP binding cassette subfamily B member 1  ABCB1  ATP-binding cassette, sub-family B (MDR/TAP), member 1  Symbol and/or name change 5135510 APPROVED