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Gene: GRIN1 (glutamate ionotropic receptor NMDA type subunit 1) Homo sapiens
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Symbol: GRIN1
Name: glutamate ionotropic receptor NMDA type subunit 1
Description: Exhibits amino acid binding activity and ionotropic glutamate receptor activity. Contributes to calcium channel activity. Involved in several processes, including calcium ion transmembrane import into cytosol; response to ethanol; and response to glycine. Localizes to the NMDA selective glutamate receptor complex and dendrite. Implicated in alcohol use disorder; autosomal dominant non-syndromic intellectual disability 8; and cerebral infarction. Biomarker of Alzheimer's disease and vascular dementia.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: GluN1; glutamate [NMDA] receptor subunit zeta 1; glutamate [NMDA] receptor subunit zeta-1; glutamate receptor ionotropic, NMDA 1; glutamate receptor, ionotropic, N-methyl D-aspartate 1; MRD8; N-methyl-D-aspartate receptor channel, subunit zeta-1; N-methyl-D-aspartate receptor subunit NR1; NDHMSD; NDHMSR; NMD-R1; NMDA1; NMDAR1; NR1
Orthologs:
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl9137,139,154 - 137,168,756 (+)Ensembl
GRCh389137,139,092 - 137,168,759 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh379140,033,609 - 140,063,214 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369139,153,430 - 139,183,029 (+)NCBINCBI36hg18NCBI36
Build 349137,308,678 - 137,339,043NCBI
Celera9110,548,072 - 110,577,040 (+)NCBI
Cytogenetic Map9q34.3NCBI
HuRef9109,493,914 - 109,523,231 (+)NCBIHuRef
CHM1_19140,182,355 - 140,211,903 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


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External Database Links
Nomenclature History
 
More on GRIN1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 731784
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-02-11
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.