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Gene: C1RL (complement C1r subcomponent like) Homo sapiens
Symbol: C1RL
Name: complement C1r subcomponent like
RGD ID: 1346889
Description: Predicted to have serine-type endopeptidase activity. Predicted to be involved in zymogen activation. Localizes to extracellular exosome; INTERACTS WITH 1-nitropyrene; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: C1r-like protein; C1r-like serine protease analog protein; C1r-LP; C1RL1; C1RLP; CLSPa; complement C1r subcomponent-like protein; complement C1r-like proteinase; complement component 1, r subcomponent-like
Mus musculus (house mouse) : C1rl (complement component 1, r subcomponent-like)  MGI  Alliance
Rattus norvegicus (Norway rat) : C1rl (complement C1r subcomponent like)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : C1rl (complement C1r subcomponent like)
Pan paniscus (bonobo/pygmy chimpanzee) : C1RL (complement C1r subcomponent like)
Canis lupus familiaris (dog) : C1RL (complement C1r subcomponent like)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : C1rl (complement C1r subcomponent like)
Sus scrofa (pig) : C1RL (complement C1r subcomponent like)
Chlorocebus sabaeus (African green monkey) : C1RL (complement C1r subcomponent like)
Heterocephalus glaber (naked mole-rat) : C1rl (complement C1r subcomponent like)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl127,089,587 - 7,109,238 (-)EnsemblGRCh38hg38GRCh38
GRCh38127,094,554 - 7,109,214 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37127,246,000 - 7,261,869 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36127,138,291 - 7,153,069 (-)NCBINCBI36hg18NCBI36
Build 34127,138,291 - 7,153,069NCBI
Celera128,823,225 - 8,838,082 (-)NCBI
Cytogenetic Map12p13.31NCBI
HuRef127,060,052 - 7,074,714 (-)NCBIHuRef
CHM1_1127,246,121 - 7,260,900 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on C1RL
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1346889
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-09-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.