Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | C1RL | Human | (1->4)-beta-D-glucan | multiple interactions | ISO | C1rl (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of C1RL mRNA | CTD | PMID:36331819 | C1RL | Human | 1,2-dimethylhydrazine | increases expression | ISO | C1rl (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in increased expression of C1RL mRNA | CTD | PMID:22206623 | C1RL | Human | 1-nitropyrene | decreases expression | EXP | | 6480464 | 1-nitropyrene results in decreased expression of C1RL mRNA | CTD | PMID:19041380 | C1RL | Human | 17beta-estradiol | multiple interactions | EXP | | 6480464 | [Estradiol co-treated with TGFB1 protein] results in decreased expression of C1RL mRNA | CTD | PMID:30165855 | C1RL | Human | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of C1RL mRNA | CTD | PMID:20106945 and PMID:21632981 | C1RL | Human | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | C1rl (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of C1RL mRNA | CTD | PMID:33387578 | C1RL | Human | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | C1rl (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of C1RL mRNA | CTD | PMID:21570461 | C1RL | Human | 3,4-methylenedioxymethamphetamine | increases expression | ISO | C1rl (Mus musculus) | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of C1RL mRNA | CTD | PMID:26251327 | C1RL | Human | 4,4'-sulfonyldiphenol | multiple interactions | ISO | C1rl (Mus musculus) | 6480464 | [bisphenol S co-treated with LIF protein] results in increased expression of C1RL mRNA | CTD | PMID:30951980 | C1RL | Human | 4,4'-sulfonyldiphenol | decreases methylation | EXP | | 6480464 | bisphenol S results in decreased methylation of C1RL gene | CTD | PMID:31601247 | C1RL | Human | 5-aza-2'-deoxycytidine | increases expression | EXP | | 6480464 | Decitabine results in increased expression of C1RL mRNA | CTD | PMID:19194470 | C1RL | Human | acetamide | decreases expression | ISO | C1rl (Rattus norvegicus) | 6480464 | acetamide results in decreased expression of C1RL mRNA | CTD | PMID:31881176 | C1RL | Human | acrylamide | decreases expression | EXP | | 6480464 | Acrylamide results in decreased expression of C1RL mRNA | CTD | PMID:32763439 | C1RL | Human | actinomycin D | multiple interactions | EXP | | 6480464 | [Dactinomycin co-treated with nutlin 3] results in increased expression of C1RL mRNA | CTD | PMID:38460933 | C1RL | Human | aflatoxin B1 | decreases expression | EXP | | 6480464 | Aflatoxin B1 results in decreased expression of C1RL mRNA | CTD | PMID:22100608 and PMID:27153756 | C1RL | Human | all-trans-retinoic acid | increases expression | EXP | | 6480464 | Tretinoin results in increased expression of C1RL mRNA | CTD | PMID:33167477 | C1RL | Human | antirheumatic drug | decreases expression | EXP | | 6480464 | Antirheumatic Agents results in decreased expression of C1RL mRNA | CTD | PMID:24449571 | C1RL | Human | benzo[a]pyrene | increases expression | EXP | | 6480464 | Benzo(a)pyrene results in increased expression of C1RL mRNA | CTD | PMID:20064835 | C1RL | Human | benzo[a]pyrene | increases methylation | ISO | C1rl (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased methylation of C1RL 3' UTR and Benzo(a)pyrene results in increased methylation of C1RL exon | CTD | PMID:27901495 | C1RL | Human | benzo[a]pyrene | increases methylation | EXP | | 6480464 | Benzo(a)pyrene results in increased methylation of C1RL promoter | CTD | PMID:27901495 | C1RL | Human | beta-lapachone | increases expression | EXP | | 6480464 | beta-lapachone results in increased expression of C1RL mRNA | CTD | PMID:38218311 | C1RL | Human | bisphenol A | increases expression | ISO | C1rl (Rattus norvegicus) | 6480464 | bisphenol A results in increased expression of C1RL mRNA | CTD | PMID:25181051 | C1RL | Human | bisphenol A | decreases expression | ISO | C1rl (Mus musculus) | 6480464 | bisphenol A results in decreased expression of C1RL protein | CTD | PMID:35999755 | C1RL | Human | bisphenol A | multiple interactions | ISO | C1rl (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with tributyltin] results in decreased expression of C1RL mRNA | CTD | PMID:31129395 | C1RL | Human | bisphenol A | decreases expression | ISO | C1rl (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of C1RL mRNA | CTD | PMID:30816183 and PMID:32145629 | C1RL | Human | bisphenol A | increases methylation | ISO | C1rl (Rattus norvegicus) | 6480464 | bisphenol A results in increased methylation of C1RL gene | CTD | PMID:28505145 | C1RL | Human | butanal | decreases expression | EXP | | 6480464 | butyraldehyde results in decreased expression of C1RL mRNA | CTD | PMID:26079696 | C1RL | Human | cadmium dichloride | decreases expression | ISO | C1rl (Rattus norvegicus) | 6480464 | Cadmium Chloride results in decreased expression of C1RL mRNA | CTD | PMID:33453195 | C1RL | Human | carbamazepine | affects expression | EXP | | 6480464 | Carbamazepine affects the expression of C1RL mRNA | CTD | PMID:25979313 | C1RL | Human | carbon nanotube | decreases expression | ISO | C1rl (Mus musculus) | 6480464 | Nanotubes and Carbon analog results in decreased expression of C1RL mRNA | CTD | PMID:25620056 | C1RL | Human | carbon nanotube | increases expression | EXP | | 6480464 | Nanotubes and Carbon results in increased expression of C1RL mRNA | CTD | PMID:29348435 | C1RL | Human | chlordecone | increases expression | ISO | C1rl (Mus musculus) | 6480464 | Chlordecone results in increased expression of C1RL mRNA | CTD | PMID:33711761 | C1RL | Human | cisplatin | multiple interactions | EXP | | 6480464 | [Cisplatin co-treated with jinfukang] results in increased expression of C1RL mRNA | CTD | PMID:27392435 | C1RL | Human | cobalt dichloride | decreases expression | EXP | | 6480464 | cobaltous chloride results in decreased expression of C1RL mRNA | CTD | PMID:19376846 | C1RL | Human | copper(II) sulfate | decreases expression | EXP | | 6480464 | Copper Sulfate results in decreased expression of C1RL mRNA | CTD | PMID:19549813 | C1RL | Human | cyclosporin A | decreases expression | EXP | | 6480464 | Cyclosporine results in decreased expression of C1RL mRNA | CTD | PMID:20106945 and PMID:25562108 | C1RL | Human | cyclosporin A | increases methylation | EXP | | 6480464 | Cyclosporine results in increased methylation of C1RL promoter | CTD | PMID:27989131 | C1RL | Human | epoxiconazole | decreases expression | ISO | C1rl (Mus musculus) | 6480464 | epoxiconazole results in decreased expression of C1RL mRNA | CTD | PMID:35436446 | C1RL | Human | ethyl methanesulfonate | increases expression | EXP | | 6480464 | Ethyl Methanesulfonate results in increased expression of C1RL mRNA | CTD | PMID:23649840 | C1RL | Human | fenthion | increases expression | ISO | C1rl (Mus musculus) | 6480464 | Fenthion results in increased expression of C1RL mRNA | CTD | PMID:34813904 | C1RL | Human | fluoranthene | multiple interactions | ISO | C1rl (Mus musculus) | 6480464 | [1-methylanthracene co-treated with fluoranthene] results in decreased expression of C1RL mRNA | CTD | PMID:28329830 | C1RL | Human | folic acid | decreases expression | ISO | C1rl (Mus musculus) | 6480464 | Folic Acid results in decreased expression of C1RL mRNA | CTD | PMID:25629700 | C1RL | Human | furan | decreases expression | ISO | C1rl (Rattus norvegicus) | 6480464 | furan results in decreased expression of C1RL mRNA | CTD | PMID:25539665 | C1RL | Human | gentamycin | increases expression | ISO | C1rl (Rattus norvegicus) | 6480464 | Gentamicins results in increased expression of C1RL mRNA | CTD | PMID:33387578 | C1RL | Human | methyl methanesulfonate | increases expression | EXP | | 6480464 | Methyl Methanesulfonate results in increased expression of C1RL mRNA | CTD | PMID:23649840 | C1RL | Human | methylmercury chloride | decreases expression | EXP | | 6480464 | methylmercuric chloride results in decreased expression of C1RL mRNA | CTD | PMID:28001369 | C1RL | Human | Nutlin-3 | multiple interactions | EXP | | 6480464 | [Dactinomycin co-treated with nutlin 3] results in increased expression of C1RL mRNA | CTD | PMID:38460933 | C1RL | Human | ozone | multiple interactions | ISO | C1rl (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased expression of C1RL mRNA | CTD | PMID:34911549 | C1RL | Human | paracetamol | affects expression | ISO | C1rl (Mus musculus) | 6480464 | Acetaminophen affects the expression of C1RL mRNA | CTD | PMID:17562736 | C1RL | Human | paracetamol | decreases expression | ISO | C1rl (Rattus norvegicus) | 6480464 | Acetaminophen results in decreased expression of C1RL mRNA | CTD | PMID:33387578 | C1RL | Human | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of C1RL mRNA | CTD | PMID:29067470 | C1RL | Human | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | C1rl (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of C1RL mRNA | CTD | PMID:36331819 | C1RL | Human | silicon dioxide | decreases expression | EXP | | 6480464 | Silicon Dioxide analog results in decreased expression of C1RL mRNA | CTD | PMID:25895662 | C1RL | Human | sodium arsenite | decreases expression | EXP | | 6480464 | sodium arsenite results in decreased expression of C1RL mRNA | CTD | PMID:38568856 | C1RL | Human | sodium arsenite | increases expression | ISO | C1rl (Mus musculus) | 6480464 | sodium arsenite results in increased expression of C1RL mRNA | CTD | PMID:37682722 | C1RL | Human | tetrachloromethane | decreases expression | ISO | C1rl (Rattus norvegicus) | 6480464 | Carbon Tetrachloride results in decreased expression of C1RL mRNA | CTD | PMID:31150632 | C1RL | Human | thimerosal | decreases expression | EXP | | 6480464 | Thimerosal results in decreased expression of C1RL mRNA | CTD | PMID:27188386 | C1RL | Human | thioacetamide | decreases expression | ISO | C1rl (Rattus norvegicus) | 6480464 | Thioacetamide results in decreased expression of C1RL mRNA | CTD | PMID:23411599 and PMID:34492290 | C1RL | Human | thiram | decreases expression | EXP | | 6480464 | Thiram results in decreased expression of C1RL mRNA | CTD | PMID:38568856 | C1RL | Human | tributylstannane | multiple interactions | ISO | C1rl (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with tributyltin] results in decreased expression of C1RL mRNA | CTD | PMID:31129395 | C1RL | Human | trichloroethene | increases expression | ISO | C1rl (Rattus norvegicus) | 6480464 | Trichloroethylene results in increased expression of C1RL mRNA | CTD | PMID:33387578 | C1RL | Human | trichostatin A | increases expression | EXP | | 6480464 | trichostatin A results in increased expression of C1RL mRNA | CTD | PMID:24935251 | C1RL | Human | triphenyl phosphate | affects expression | EXP | | 6480464 | triphenyl phosphate affects the expression of C1RL mRNA | CTD | PMID:37042841 | C1RL | Human | trovafloxacin | decreases expression | ISO | C1rl (Mus musculus) | 6480464 | trovafloxacin results in decreased expression of C1RL mRNA | CTD | PMID:35537566 | C1RL | Human | urethane | decreases expression | EXP | | 6480464 | Urethane results in decreased expression of C1RL mRNA | CTD | PMID:28818685 | C1RL | Human | valproic acid | decreases methylation | EXP | | 6480464 | Valproic Acid results in decreased methylation of C1RL gene | CTD | PMID:29154799 | C1RL | Human | valproic acid | affects expression | ISO | C1rl (Mus musculus) | 6480464 | Valproic Acid affects the expression of C1RL mRNA | CTD | PMID:17292431 | C1RL | Human | valproic acid | decreases expression | EXP | | 6480464 | Valproic Acid results in decreased expression of C1RL mRNA | CTD | PMID:23179753 more ... | C1RL | Human | valproic acid | affects expression | EXP | | 6480464 | Valproic Acid affects the expression of C1RL mRNA | CTD | PMID:25979313 | C1RL | Human | valproic acid | increases expression | EXP | | 6480464 | Valproic Acid results in increased expression of C1RL mRNA | CTD | PMID:24935251 | |