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GENE - TERM ANNOTATION REPORT

RGD ID: 1346889
Species: Homo sapiens
RGD Object: Gene
Symbol: C1RL
Name: complement C1r subcomponent like
Acc ID: GO:0004252
Term: serine-type endopeptidase activity
Definition: Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).
Definition Source(s): GOC:mah, https://www.ebi.ac.uk/merops/about/glossary.shtml#CATTYPE
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
C1RLenablesIBAMGI:88492 or PANTHER:PTN001207255 or Masp1 (Rattus norvegicus) or Masp2 (Rattus norvegicus) or UniProtKB:O00187 or UniProtKB:P00736 or UniProtKB:P09871 or UniProtKB:P48740150520179GO_Central GO_REF:0000033
C1RLenablesIEAInterPro:IPR001254150520179InterPro GO_REF:0000002
C1RLenablesIEAPANTHER:PTHR24255:SF26150520179TreeGrafter GO_REF:0000118
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