Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dimethylhydrazine | decreases expression | ISO | Prrg3 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of PRRG3 mRNA | CTD | PMID:22206623 | 2,2',4,4',5,5'-hexachlorobiphenyl | multiple interactions | ISO | Prrg3 (Mus musculus) | 6480464 | [2 more ... | CTD | PMID:25510870 | 2,2',5,5'-tetrachlorobiphenyl | multiple interactions | ISO | Prrg3 (Mus musculus) | 6480464 | [2 more ... | CTD | PMID:25510870 | 2-palmitoylglycerol | increases expression | EXP | | 6480464 | 2-palmitoylglycerol results in increased expression of PRRG3 mRNA | CTD | PMID:37199045 | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | EXP | | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of PRRG3 mRNA | CTD | PMID:28628672 | 4-hydroxyphenyl retinamide | decreases expression | ISO | Prrg3 (Mus musculus) | 6480464 | Fenretinide results in decreased expression of PRRG3 mRNA | CTD | PMID:28973697 | acrylamide | decreases expression | EXP | | 6480464 | Acrylamide results in decreased expression of PRRG3 mRNA | CTD | PMID:32763439 | antirheumatic drug | increases expression | EXP | | 6480464 | Antirheumatic Agents results in increased expression of PRRG3 mRNA | CTD | PMID:24449571 | benzo[a]pyrene | multiple interactions | ISO | Prrg3 (Mus musculus) | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of PRRG3 mRNA | CTD | PMID:27858113 | benzo[a]pyrene | decreases methylation | EXP | | 6480464 | Benzo(a)pyrene results in decreased methylation of PRRG3 5' UTR | CTD | PMID:27901495 | benzo[a]pyrene | increases expression | ISO | Prrg3 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of PRRG3 mRNA | CTD | PMID:32417428 | benzo[a]pyrene | affects methylation | EXP | | 6480464 | Benzo(a)pyrene affects the methylation of PRRG3 promoter | CTD | PMID:27901495 | benzo[b]fluoranthene | multiple interactions | ISO | Prrg3 (Mus musculus) | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of PRRG3 mRNA | CTD | PMID:27858113 | bisphenol A | decreases expression | ISO | Prrg3 (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of PRRG3 mRNA | CTD | PMID:25181051 | bisphenol A | multiple interactions | ISO | Prrg3 (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with tributyltin] results in decreased expression of PRRG3 mRNA | CTD | PMID:31129395 | bisphenol F | multiple interactions | EXP | | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of PRRG3 mRNA | CTD | PMID:28628672 | carbon nanotube | increases expression | ISO | Prrg3 (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | CGP 52608 | multiple interactions | EXP | | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to PRRG3 gene] | CTD | PMID:28238834 | chlordecone | increases expression | ISO | Prrg3 (Mus musculus) | 6480464 | Chlordecone results in increased expression of PRRG3 mRNA | CTD | PMID:33711761 | chloroprene | increases expression | ISO | Prrg3 (Mus musculus) | 6480464 | Chloroprene results in increased expression of PRRG3 mRNA | CTD | PMID:23125180 | chrysene | multiple interactions | ISO | Prrg3 (Mus musculus) | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of PRRG3 mRNA | CTD | PMID:27858113 | dexamethasone | multiple interactions | EXP | | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of PRRG3 mRNA | CTD | PMID:28628672 | dibenz[a,h]anthracene | increases expression | ISO | Prrg3 (Mus musculus) | 6480464 | 1 more ... | CTD | PMID:26377693 | dorsomorphin | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PRRG3 mRNA | CTD | PMID:27188386 | folic acid | decreases expression | ISO | Prrg3 (Mus musculus) | 6480464 | Folic Acid results in decreased expression of PRRG3 mRNA | CTD | PMID:25629700 | indometacin | multiple interactions | EXP | | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of PRRG3 mRNA | CTD | PMID:28628672 | nickel atom | decreases expression | EXP | | 6480464 | Nickel results in decreased expression of PRRG3 mRNA | CTD | PMID:25583101 | ozone | decreases expression | ISO | Prrg3 (Rattus norvegicus) | 6480464 | Ozone results in decreased expression of PRRG3 mRNA | CTD | PMID:28623178 | paraquat | decreases expression | ISO | Prrg3 (Rattus norvegicus) | 6480464 | Paraquat results in decreased expression of PRRG3 mRNA | CTD | PMID:32680482 | PCB138 | multiple interactions | ISO | Prrg3 (Mus musculus) | 6480464 | [2 more ... | CTD | PMID:25510870 | SB 431542 | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PRRG3 mRNA | CTD | PMID:27188386 | sodium arsenite | increases expression | EXP | | 6480464 | sodium arsenite results in increased expression of PRRG3 mRNA | CTD | PMID:29301061 | sunitinib | decreases expression | EXP | | 6480464 | Sunitinib results in decreased expression of PRRG3 mRNA | CTD | PMID:31533062 | tetrachloromethane | affects expression | ISO | Prrg3 (Mus musculus) | 6480464 | Carbon Tetrachloride affects the expression of PRRG3 mRNA | CTD | PMID:17484886 | tetraphene | multiple interactions | ISO | Prrg3 (Mus musculus) | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of PRRG3 mRNA | CTD | PMID:27858113 | tributylstannane | multiple interactions | ISO | Prrg3 (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with tributyltin] results in decreased expression of PRRG3 mRNA | CTD | PMID:31129395 | valproic acid | increases methylation | EXP | | 6480464 | Valproic Acid results in increased methylation of PRRG3 gene | CTD | PMID:29154799 | valproic acid | decreases expression | EXP | | 6480464 | Valproic Acid results in decreased expression of PRRG3 mRNA | CTD | PMID:23179753 and PMID:26272509 | valproic acid | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PRRG3 mRNA | CTD | PMID:27188386 | vorinostat | decreases expression | EXP | | 6480464 | vorinostat results in decreased expression of PRRG3 mRNA | CTD | PMID:27188386 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Gene Ontology Annotations Click to see Annotation Detail View
Biological Process
Cellular Component
Molecular Function
Phenotype Annotations Click to see Annotation Detail View
Imported Human Phenotype Annotations - ClinVar
Disease Annotations
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Gene-Chemical Interaction Annotations
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Gene Ontology Annotations
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Phenotype Annotations
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References
References - curated
| # | Reference Title | Reference Citation |
| 1. | GOAs Human GO annotations | GOA_HUMAN data from the GO Consortium |
| 2. | ClinVar Automated Import and Annotation Pipeline | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
| 3. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
Additional References at PubMed
| PMID:11171957 | PMID:12477932 | PMID:14702039 | PMID:15203218 | PMID:16303743 | PMID:21873635 | PMID:26186194 | PMID:28514442 | PMID:33961781 |
Genomics
Comparative Map Data
| PRRG3 (Homo sapiens - human) |
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| Prrg3 (Mus musculus - house mouse) |
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| Prrg3 (Rattus norvegicus - Norway rat) |
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| Prrg3 (Chinchilla lanigera - long-tailed chinchilla) |
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| PRRG3 (Pan paniscus - bonobo/pygmy chimpanzee) |
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| PRRG3 (Canis lupus familiaris - dog) |
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| Prrg3 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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| PRRG3 (Sus scrofa - pig) |
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| LOC103232749 (Chlorocebus sabaeus - green monkey) |
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| Prrg3 (Heterocephalus glaber - naked mole-rat) |
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Variants
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Variants in PRRG3
21 total Variants 
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