RNF39 (ring finger protein 39) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: RNF39 (ring finger protein 39) Homo sapiens
Analyze
Symbol: RNF39
Name: ring finger protein 39
RGD ID: 1604283
HGNC Page HGNC:18064
Description: Enables ubiquitin protein ligase activity. Involved in negative regulation of cytoplasmic pattern recognition receptor signaling pathway; positive regulation of cGAS/STING signaling pathway; and protein K63-linked ubiquitination. Is active in cytoplasm. Biomarker of cholangiocarcinoma.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: FAP216; HZF; HZFW; LIRF; LTP (long-term potentiation) induced RING finger protein
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38630,070,270 - 30,075,769 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl630,070,266 - 30,075,849 (-)EnsemblGRCh38hg38GRCh38
GRCh37630,038,047 - 30,043,546 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36630,146,022 - 30,151,607 (-)NCBINCBI36Build 36hg18NCBI36
Celera631,636,296 - 31,641,881 (-)NCBICelera
Cytogenetic Map6p22.1NCBI
HuRef629,836,215 - 29,841,800 (-)NCBIHuRef
CHM1_1630,040,092 - 30,045,677 (-)NCBICHM1_1
T2T-CHM13v2.0629,934,544 - 29,940,043 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
RNF39Humancholangiocarcinoma disease_progressionIEP 152998978mRNA:altered expression:liver (human)RGD 
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
RNF39Humanmegacolon  IAGPRGD:414076048554872ClinVar Annotator: match by term: MegacolonClinVarPMID:21681106
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
RNF39HumanExperimental Liver Cirrhosis  EXP 11554173CTD Direct Evidence: marker/mechanismCTDPMID:25380136

1 to 20 of 74 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
RNF39Human1,2-dichloroethane decreases expressionISORGD:16211756480464ethylene dichloride results in decreased expression of RNF39 mRNACTDPMID:28960355
RNF39Human1-naphthyl isothiocyanate decreases expressionISORGD:62885464804641-Naphthylisothiocyanate results in decreased expression of RNF39 mRNACTDPMID:25380136
RNF39Human17beta-estradiol multiple interactionsEXP 6480464[Estradiol co-treated with TGFB1 protein] results in decreased expression of RNF39 mRNACTDPMID:30165855
RNF39Human17beta-estradiol decreases expressionISORGD:16211756480464Estradiol results in decreased expression of RNF39 mRNACTDPMID:39298647
RNF39Human2,3,7,8-tetrachlorodibenzodioxine decreases expressionISORGD:6288546480464Tetrachlorodibenzodioxin results in decreased expression of RNF39 mRNACTDPMID:19490992|PMID:21215274
RNF39Human2,3,7,8-tetrachlorodibenzodioxine increases expressionISORGD:6288546480464Tetrachlorodibenzodioxin results in increased expression of RNF39 mRNACTDPMID:33387578
RNF39Human2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISORGD:16211756480464[Tetrachlorodibenzodioxin affects the methylation of RNF39 intron] which results in decreased expression of RNF39 mRNACTDPMID:33017471
RNF39Human2,3,7,8-tetrachlorodibenzodioxine increases expressionISORGD:16211756480464Tetrachlorodibenzodioxin results in increased expression of RNF39 mRNACTDPMID:28922406
RNF39Human2,4-dinitrotoluene affects expressionISORGD:62885464804642,4-dinitrotoluene affects the expression of RNF39 mRNACTDPMID:21346803
RNF39Human4,4'-diaminodiphenylmethane decreases expressionISORGD:62885464804644,4'-diaminodiphenylmethane results in decreased expression of RNF39 mRNACTDPMID:25380136
RNF39Human4,4'-sulfonyldiphenol decreases expressionISORGD:16211756480464bisphenol S results in decreased expression of RNF39 mRNACTDPMID:39298647
RNF39Human5-aza-2'-deoxycytidine affects expressionEXP 6480464Decitabine affects the expression of RNF39 mRNACTDPMID:23300844
RNF39Human6-propyl-2-thiouracil decreases expressionISORGD:6288546480464Propylthiouracil results in decreased expression of RNF39 mRNACTDPMID:24780913
RNF39Humanacetamide decreases expressionISORGD:6288546480464acetamide results in decreased expression of RNF39 mRNACTDPMID:31881176
RNF39Humanaflatoxin B1 increases expressionISORGD:6288546480464Aflatoxin B1 results in increased expression of RNF39 mRNACTDPMID:33354967
RNF39Humanall-trans-retinoic acid decreases expressionISORGD:6288546480464Tretinoin results in decreased expression of RNF39 mRNACTDPMID:20488242
RNF39Humanammonium chloride affects expressionISORGD:6288546480464Ammonium Chloride affects the expression of RNF39 mRNACTDPMID:16483693
RNF39Humanaristolochic acid A increases expressionEXP 6480464aristolochic acid I results in increased expression of RNF39 mRNACTDPMID:33212167
RNF39Humanatrazine increases expressionEXP 6480464Atrazine results in increased expression of RNF39 mRNACTDPMID:22378314
RNF39Humanbenzo[a]pyrene decreases methylationEXP 6480464Benzo(a)pyrene results in decreased methylation of RNF39 3' UTR; Benzo(a)pyrene results in decreased methylation of more ...CTDPMID:27901495

1 to 20 of 74 rows

Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
RNF39Humaninnate immune response involved_inIBAMGI:1338757|MGI:2137355|MGI:2385051|MGI:97904|PANTHER:PTN000762195|UniProtKB:O15553|UniProtKB:O60858|UniProtKB:P14373|UniProtKB:P19474|UniProtKB:Q0PF16|UniProtKB:Q12899|UniProtKB:Q14142|UniProtKB:Q96F44|UniProtKB:Q9BVG3|UniProtKB:Q9BZY9|UniProtKB:Q9C019|UniProtKB:Q9C029|UniProtKB:Q9C030|UniProtKB:Q9C035|UniProtKB:Q9UPQ4150520179 GO_CentralGO_REF:0000033
RNF39Humannegative regulation of cytoplasmic pattern recognition receptor signaling pathway involved_inIDA 150520179 PMID:33674311UniProtPMID:33674311
RNF39Humanpositive regulation of cGAS/STING signaling pathway involved_inIDA 150520179 PMID:39255680UniProtPMID:39255680
RNF39Humanprotein K63-linked ubiquitination involved_inIDA 150520179 PMID:39255680UniProtPMID:39255680

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
RNF39Humancytoplasm located_inIEAUniProtKB-SubCell:SL-0086150520179 UniProtGO_REF:0000044
RNF39Humancytoplasm is_active_inIDA 150520179 PMID:33674311, PMID:39255680UniProtPMID:33674311|PMID:39255680
RNF39Humancytoplasm located_inIEAUniProtKB-KW:KW-0963150520179 UniProtGO_REF:0000043
RNF39Humancytoplasm is_active_inIBAMGI:106657|MGI:1337056|MGI:1338757|MGI:1913847|MGI:1914104|MGI:1923931|MGI:2137352|MGI:2137353|MGI:2137355|MGI:2149590|MGI:3612190|MGI:97904|MGI:98178|PANTHER:PTN007774218|RGD:1304877|RGD:619964|RGD:708400|UniProtKB:O15553|UniProtKB:O60858|UniProtKB:O75677|UniProtKB:P14373|UniProtKB:P19474|UniProtKB:Q0PF16|UniProtKB:Q12899|UniProtKB:Q14142|UniProtKB:Q6AZZ1|UniProtKB:Q6P9F5|UniProtKB:Q86UV6|UniProtKB:Q86UV7|UniProtKB:Q86WT6|UniProtKB:Q86XT4|UniProtKB:Q8IWZ4|UniProtKB:Q8IYM9|UniProtKB:Q969Q1|UniProtKB:Q96A61|UniProtKB:Q96F44|UniProtKB:Q9BVG3|UniProtKB:Q9BYJ4|UniProtKB:Q9BZY9|UniProtKB:Q9C029|UniProtKB:Q9C030|UniProtKB:Q9C035|UniProtKB:Q9C037|UniProtKB:Q9HCM9150520179 GO_CentralGO_REF:0000033

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
RNF39Humanmetal ion binding enablesIEAUniProtKB-KW:KW-0479150520179 UniProtGO_REF:0000043
RNF39Humanprotein binding enablesIPIUniProtKB:A6NEM1|UniProtKB:Q10567-3|UniProtKB:Q15276|UniProtKB:Q6NUQ1|UniProtKB:Q6PF18|UniProtKB:Q7Z3Y8|UniProtKB:Q9NQM4150520179 PMID:32296183IntActPMID:32296183
RNF39Humantransferase activity enablesIEAUniProtKB-KW:KW-0808150520179 UniProtGO_REF:0000043
RNF39Humanubiquitin protein ligase activity enablesIBAMGI:2137355|MGI:2385051|MGI:2447992|MGI:2684862|MGI:2684869|MGI:3612190|PANTHER:PTN007774218|UniProtKB:P14373|UniProtKB:P19474|UniProtKB:Q12899|UniProtKB:Q86WT6|UniProtKB:Q8IYM9|UniProtKB:Q8WV44|UniProtKB:Q969Q1|UniProtKB:Q96A61|UniProtKB:Q9BVG3|UniProtKB:Q9BYV6|UniProtKB:Q9BZY9|UniProtKB:Q9C029|UniProtKB:Q9C030150520179 GO_CentralGO_REF:0000033
RNF39Humanubiquitin protein ligase activity enablesIDA 150520179 PMID:33674311, PMID:39255680UniProtPMID:33674311|PMID:39255680
RNF39Humanzinc ion binding enablesIEAUniProtKB-KW:KW-0863150520179 UniProtGO_REF:0000043

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
RNF39HumanMegacolon  IAGPRGD:414076048554872ClinVar Annotator: match by term: MegacolonClinVarPMID:21681106

#
Reference Title
Reference Citation
1. Identification of key genes and pathways associated with cholangiocarcinoma development based on weighted gene correlation network analysis. Liu J, etal., PeerJ. 2019 Oct 31;7:e7968. doi: 10.7717/peerj.7968. eCollection 2019.
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:8889548   PMID:10585558   PMID:11006080   PMID:11076863   PMID:11130983   PMID:11716498   PMID:12477932   PMID:14574404   PMID:17719541   PMID:19050382   PMID:19115949   PMID:19693088  
PMID:19851445   PMID:20041166   PMID:20593013   PMID:20875797   PMID:21873635   PMID:24489884   PMID:28149331   PMID:28729889   PMID:32296183   PMID:33674311   PMID:39255680  



RNF39
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38630,070,270 - 30,075,769 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl630,070,266 - 30,075,849 (-)EnsemblGRCh38hg38GRCh38
GRCh37630,038,047 - 30,043,546 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36630,146,022 - 30,151,607 (-)NCBINCBI36Build 36hg18NCBI36
Celera631,636,296 - 31,641,881 (-)NCBICelera
Cytogenetic Map6p22.1NCBI
HuRef629,836,215 - 29,841,800 (-)NCBIHuRef
CHM1_1630,040,092 - 30,045,677 (-)NCBICHM1_1
T2T-CHM13v2.0629,934,544 - 29,940,043 (-)NCBIT2T-CHM13v2.0
Rnf39
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391737,253,943 - 37,258,878 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1737,253,810 - 37,258,878 (+)EnsemblGRCm39 Ensembl
GRCm381736,943,051 - 36,947,986 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1736,942,918 - 36,947,986 (+)EnsemblGRCm38mm10GRCm38
MGSCv371737,079,996 - 37,084,931 (+)NCBIGRCm37MGSCv37mm9NCBIm37
Celera1740,366,596 - 40,371,525 (+)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1719.16NCBI
Rnf39
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8201,610,027 - 1,615,516 (-)NCBIGRCr8
mRatBN7.2201,604,794 - 1,610,283 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl201,604,794 - 1,610,283 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx201,657,567 - 1,663,054 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0201,661,064 - 1,666,549 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0201,602,535 - 1,608,038 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0202,098,375 - 2,103,864 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl202,098,375 - 2,103,864 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0204,135,089 - 4,140,578 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4201,697,530 - 1,703,019 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1201,697,529 - 1,703,019 (-)NCBI
Celera202,313,358 - 2,318,849 (-)NCBICelera
Cytogenetic Map20p12NCBI
Rnf39
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_004955583201,638 - 206,754 (-)NCBIChiLan1.0ChiLan1.0
RNF39
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2544,663,536 - 44,669,354 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1640,626,537 - 40,632,281 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0629,848,055 - 29,853,659 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1630,518,327 - 30,523,597 (-)NCBIpanpan1.1PanPan1.1panPan2
RNF39
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13526,292,218 - 26,296,980 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3526,292,781 - 26,297,083 (-)EnsemblCanFam3.1canFam3CanFam3.1
ROS_Cfam_1.03526,600,790 - 26,605,478 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3526,601,338 - 26,605,630 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13526,255,356 - 26,260,068 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03526,316,600 - 26,320,753 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03527,786,250 - 27,790,957 (-)NCBIUU_Cfam_GSD_1.0
Rnf39
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494632,619,246 - 32,624,624 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936723967,263 - 975,952 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936723967,376 - 972,496 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RNF39
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl722,636,904 - 22,642,612 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1722,637,732 - 22,642,427 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2724,985,817 - 24,990,520 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RNF39
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11742,423,486 - 42,429,631 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1742,424,126 - 42,428,787 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604429,725,245 - 29,731,196 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rnf39
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475425,331,070 - 25,335,153 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475425,331,126 - 25,348,957 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

.
Variants in RNF39
33 total Variants

1 to 10 of 49 rows
Name
Type
Condition(s)
Position(s)
Clinical significance
GRCh38/hg38 6p22.3-21.33(chr6:18120520-30767516)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052180]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052180]|See cases [RCV000052180] Chr6:18120520..30767516 [GRCh38]
Chr6:18120751..30735293 [GRCh37]
Chr6:18228730..30843272 [NCBI36]
Chr6:6p22.3-21.33
pathogenic
NM_021959.2(PPP1R11):c.361C>T (p.Pro121Ser) single nucleotide variant Malignant melanoma [RCV000061381] Chr6:30069286 [GRCh38]
Chr6:30037063 [GRCh37]
Chr6:30145042 [NCBI36]
Chr6:6p22.1
not provided
NM_021959.2(PPP1R11):c.332C>T (p.Pro111Leu) single nucleotide variant Malignant melanoma [RCV000067266] Chr6:30069257 [GRCh38]
Chr6:30037034 [GRCh37]
Chr6:30145013 [NCBI36]
Chr6:6p22.1
not provided
GRCh38/hg38 6p25.2-21.33(chr6:3224310-30657190)x3 copy number gain See cases [RCV000138956] Chr6:3224310..30657190 [GRCh38]
Chr6:3224544..30624967 [GRCh37]
Chr6:3169543..30732946 [NCBI36]
Chr6:6p25.2-21.33
pathogenic
GRCh38/hg38 6p25.3-12.3(chr6:156974-46789291)x3 copy number gain See cases [RCV000143497] Chr6:156974..46789291 [GRCh38]
Chr6:156974..46757028 [GRCh37]
Chr6:101974..46864987 [NCBI36]
Chr6:6p25.3-12.3
pathogenic
chr6:29910378..30075843 complex variant complex Breast ductal adenocarcinoma [RCV000207211] Chr6:29910378..30075843 [GRCh37]
Chr6:6p22.1
uncertain significance
GRCh37/hg19 6p25.3-q27(chr6:156975-170919482)x3 copy number gain See cases [RCV000512067] Chr6:156975..170919482 [GRCh37]
Chr6:6p25.3-q27
pathogenic
GRCh37/hg19 6p25.3-q27(chr6:156975-170919482) copy number gain See cases [RCV000510595] Chr6:156975..170919482 [GRCh37]
Chr6:6p25.3-q27
pathogenic
GRCh37/hg19 6p22.1-q14.1(chr6:29455465-81447367) copy number gain not provided [RCV000767714] Chr6:29455465..81447367 [GRCh37]
Chr6:6p22.1-q14.1
pathogenic
NM_025236.3(RNF39):c.14A>T (p.Asp5Val) single nucleotide variant not specified [RCV004665521] Chr6:30075776 [GRCh38]
Chr6:30043553 [GRCh37]
Chr6:6p22.1
uncertain significance
1 to 10 of 49 rows

Predicted Target Of
Summary Value
Count of predictions:1251
Count of miRNA genes:329
Interacting mature miRNAs:348
Transcripts:ENST00000244360, ENST00000376751
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 16 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1358839MULTSCL5_HMultiple sclerosis susceptibility QTL 5 (human)Multiple sclerosis susceptibility61958431145584311Human
597078225GWAS1174299_Hnon-obstructive coronary artery disease QTL GWAS1174299 (human)0.0000007non-obstructive coronary artery disease63007146330071464Human
1643377BW325_HBody weight QTL 325 (human)2.320.0005Body fat amount6691196032911960Human
1643569GLUCO21_HGlucose level QTL 21 (human)0.021Glucose levelnon-insulin-dependent6691196032911960Human
597066878GWAS1162952_Hsusceptibility to chickenpox measurement QTL GWAS1162952 (human)1e-10response to viral infection trait (VT:0010439)63007251430072515Human
1298458BW9_HBody weight QTL 9 (human)2.70.0002Body fat amount6691196032911960Human
597179409GWAS1275483_Hhemoglobin measurement QTL GWAS1275483 (human)8e-17hemoglobin measurementhemoglobin measurement (CMO:0000508)63007087030070871Human
1298431RA11_HRheumatoid arthritis QTL 11 (human)0.0000024Joint/bone inflammationrheumatoid arthritis61991188340191709Human
597195636GWAS1291710_Hintelligence QTL GWAS1291710 (human)3e-09intelligence63007087030070871Human
597048987GWAS1145061_Hcervical carcinoma QTL GWAS1145061 (human)7e-09cervical carcinoma63007522330075224Human

1 to 10 of 16 rows
G31541  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37630,038,717 - 30,038,828UniSTSGRCh37
Build 36630,146,696 - 30,146,807RGDNCBI36
Celera631,636,970 - 31,637,081RGD
Cytogenetic Map6p21.3UniSTS
HuRef629,836,889 - 29,837,000UniSTS
RH99256  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37630,041,144 - 30,041,302UniSTSGRCh37
Build 36630,149,123 - 30,149,281RGDNCBI36
Celera631,639,397 - 31,639,555RGD
Cytogenetic Map6p21.3UniSTS
HuRef629,839,316 - 29,839,474UniSTS
GeneMap99-GB4 RH Map6117.14UniSTS
RNF39_1552.2  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37630,038,029 - 30,038,779UniSTSGRCh37
Build 36630,146,008 - 30,146,758RGDNCBI36
Celera631,636,282 - 31,637,032RGD
HuRef629,836,201 - 29,836,951UniSTS
G29206  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37630,037,875 - 30,038,014UniSTSGRCh37
Build 36630,145,854 - 30,145,993RGDNCBI36
Celera631,636,128 - 31,636,267RGD
Cytogenetic Map6p21.3UniSTS
HuRef629,836,047 - 29,836,186UniSTS
STS-R63837  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37630,041,559 - 30,041,681UniSTSGRCh37
Build 36630,149,538 - 30,149,660RGDNCBI36
Celera631,639,812 - 31,639,934RGD
Cytogenetic Map6p21.3UniSTS
HuRef629,839,731 - 29,839,853UniSTS
GeneMap99-GB4 RH Map6117.03UniSTS
NCBI RH Map6396.6UniSTS
STS-W44579  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37630,037,733 - 30,037,892UniSTSGRCh37
Build 36630,145,712 - 30,145,871RGDNCBI36
Celera631,635,986 - 31,636,145RGD
Cytogenetic Map6p21.3UniSTS
HuRef629,835,905 - 29,836,064UniSTS
GeneMap99-GB4 RH Map6117.03UniSTS
NCBI RH Map6396.6UniSTS




adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
1204 2428 2787 2233 4935 1710 2318 4 613 1890 455 2263 7189 6382 42 3704 840 1729 1594 170


1 to 30 of 38 rows
RefSeq Transcripts NM_025236 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_170769 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017011325 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017011326 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054328523 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054329914 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054330406 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054330685 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054330899 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054331419 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054356472 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB088087 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB202082 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF238315 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF238316 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF238317 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL669914 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL671859 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL845439 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BA000025 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX088647 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX927229 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CA311242 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471081 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068272 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR388205 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR759763 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR759960 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR933538 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KY500606 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
1 to 30 of 38 rows

Ensembl Acc Id: ENST00000244360   ⟹   ENSP00000244360
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl630,070,270 - 30,075,769 (-)Ensembl
Ensembl Acc Id: ENST00000376751   ⟹   ENSP00000365942
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl630,070,266 - 30,075,849 (-)Ensembl
RefSeq Acc Id: NM_025236   ⟹   NP_079512
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38630,070,270 - 30,075,769 (-)NCBI
GRCh37630,038,043 - 30,043,628 (-)RGD
Build 36630,146,022 - 30,151,607 (-)NCBI Archive
Celera631,636,296 - 31,641,881 (-)RGD
HuRef629,836,215 - 29,841,800 (-)RGD
CHM1_1630,040,092 - 30,045,677 (-)NCBI
T2T-CHM13v2.0629,934,544 - 29,940,043 (-)NCBI
Sequence:
RefSeq Acc Id: NM_170769   ⟹   NP_739575
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38630,070,270 - 30,075,769 (-)NCBI
GRCh37630,038,043 - 30,043,628 (-)RGD
Build 36630,146,022 - 30,151,607 (-)NCBI Archive
Celera631,636,296 - 31,641,881 (-)RGD
HuRef629,836,215 - 29,841,800 (-)RGD
CHM1_1630,040,092 - 30,045,675 (-)NCBI
T2T-CHM13v2.0629,934,544 - 29,940,043 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017011325   ⟹   XP_016866814
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38630,070,270 - 30,075,769 (-)NCBI
Sequence:
RefSeq Acc Id: XM_054356472   ⟹   XP_054212447
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0629,934,544 - 29,940,043 (-)NCBI
1 to 30 of 44 rows
Protein RefSeqs NP_079512 (Get FASTA)   NCBI Sequence Viewer  
  NP_739575 (Get FASTA)   NCBI Sequence Viewer  
  XP_016866814 (Get FASTA)   NCBI Sequence Viewer  
  XP_054184498 (Get FASTA)   NCBI Sequence Viewer  
  XP_054185889 (Get FASTA)   NCBI Sequence Viewer  
  XP_054186381 (Get FASTA)   NCBI Sequence Viewer  
  XP_054186660 (Get FASTA)   NCBI Sequence Viewer  
  XP_054186874 (Get FASTA)   NCBI Sequence Viewer  
  XP_054187394 (Get FASTA)   NCBI Sequence Viewer  
  XP_054212447 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAG40628 (Get FASTA)   NCBI Sequence Viewer  
  AAG40629 (Get FASTA)   NCBI Sequence Viewer  
  AAG40630 (Get FASTA)   NCBI Sequence Viewer  
  AQY77078 (Get FASTA)   NCBI Sequence Viewer  
  AQY77079 (Get FASTA)   NCBI Sequence Viewer  
  AQY77080 (Get FASTA)   NCBI Sequence Viewer  
  AQY77081 (Get FASTA)   NCBI Sequence Viewer  
  AQY77082 (Get FASTA)   NCBI Sequence Viewer  
  AQY77083 (Get FASTA)   NCBI Sequence Viewer  
  AQY77084 (Get FASTA)   NCBI Sequence Viewer  
  AQY77085 (Get FASTA)   NCBI Sequence Viewer  
  AQY77086 (Get FASTA)   NCBI Sequence Viewer  
  BAB63333 (Get FASTA)   NCBI Sequence Viewer  
  BAC54920 (Get FASTA)   NCBI Sequence Viewer  
  BAE78602 (Get FASTA)   NCBI Sequence Viewer  
  EAX03255 (Get FASTA)   NCBI Sequence Viewer  
  EAX03256 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSP00000244360
  ENSP00000244360.7
  ENSP00000365941.2
1 to 30 of 44 rows
RefSeq Acc Id: NP_079512   ⟸   NM_025236
- Peptide Label: isoform 1
- UniProtKB: Q9H2S5 (UniProtKB/Swiss-Prot),   Q9H2S4 (UniProtKB/Swiss-Prot),   Q9H2S3 (UniProtKB/Swiss-Prot),   Q5SS29 (UniProtKB/Swiss-Prot),   Q5SRK1 (UniProtKB/Swiss-Prot),   Q5SRJ9 (UniProtKB/Swiss-Prot),   Q5SPN0 (UniProtKB/Swiss-Prot),   Q5SPM9 (UniProtKB/Swiss-Prot),   Q5SPM8 (UniProtKB/Swiss-Prot),   B0S858 (UniProtKB/Swiss-Prot),   A6NCD6 (UniProtKB/Swiss-Prot),   A2BEK3 (UniProtKB/Swiss-Prot),   Q96QB5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_739575   ⟸   NM_170769
- Peptide Label: isoform 2
- UniProtKB: A0A1U9X8G2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_016866814   ⟸   XM_017011325
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSP00000244360   ⟸   ENST00000244360
Ensembl Acc Id: ENSP00000365942   ⟸   ENST00000376751
B30.2/SPRY   RING-type

Name Modeler Protein Id AA Range Protein Structure
AF-Q9H2S5-F1-model_v2 AlphaFold Q9H2S5 1-420 view protein structure

RGD ID:6872352
Promoter ID:EPDNEW_H9341
Type:initiation region
Name:RNF39_1
Description:ring finger protein 39
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38630,075,769 - 30,075,829EPDNEW
RGD ID:6813068
Promoter ID:HG_ACW:67893
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   Lymphoblastoid
Transcripts:RNF39.CAPR07-UNSPLICED,   SPAKLUBU.AAPR07-UNSPLICED,   SPYKLUBU.AAPR07-UNSPLICED
Position:
Human AssemblyChrPosition (strand)Source
Build 36630,146,904 - 30,147,404 (-)MPROMDB
RGD ID:6804622
Promoter ID:HG_KWN:52795
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:HeLa_S3
Transcripts:ENST00000376746,   OTTHUMT00000076625,   OTTHUMT00000076626
Position:
Human AssemblyChrPosition (strand)Source
Build 36630,151,496 - 30,151,996 (-)MPROMDB


1 to 40 of 93 rows
Database
Acc Id
Source(s)
COSMIC RNF39 COSMIC
Ensembl Genes ENSG00000204618 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
  ENSG00000206500 UniProtKB/Swiss-Prot
  ENSG00000227171 UniProtKB/Swiss-Prot
  ENSG00000230332 UniProtKB/Swiss-Prot
  ENSG00000230467 UniProtKB/Swiss-Prot
  ENSG00000235022 UniProtKB/Swiss-Prot
  ENSG00000236967 UniProtKB/Swiss-Prot
  ENSG00000237733 UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000244360 ENTREZGENE
  ENST00000244360.8 UniProtKB/Swiss-Prot
  ENST00000376750.6 UniProtKB/Swiss-Prot
  ENST00000376751 ENTREZGENE
  ENST00000376751.8 UniProtKB/Swiss-Prot
  ENST00000417541.6 UniProtKB/Swiss-Prot
  ENST00000425956.6 UniProtKB/Swiss-Prot
  ENST00000432647.2 UniProtKB/Swiss-Prot
  ENST00000441449.6 UniProtKB/Swiss-Prot
  ENST00000442063.2 UniProtKB/Swiss-Prot
  ENST00000442378.2 UniProtKB/Swiss-Prot
  ENST00000449145.2 UniProtKB/Swiss-Prot
  ENST00000450015.2 UniProtKB/Swiss-Prot
  ENST00000451425.6 UniProtKB/Swiss-Prot
  ENST00000456156.6 UniProtKB/Swiss-Prot
  ENST00000457092.6 UniProtKB/Swiss-Prot
Gene3D-CATH 2.60.120.920 UniProtKB/Swiss-Prot
  3.30.40.10 UniProtKB/Swiss-Prot
GTEx ENSG00000204618 GTEx
  ENSG00000206500 GTEx
  ENSG00000227171 GTEx
  ENSG00000230332 GTEx
  ENSG00000230467 GTEx
  ENSG00000235022 GTEx
  ENSG00000236967 GTEx
  ENSG00000237733 GTEx
HGNC ID HGNC:18064 ENTREZGENE
Human Proteome Map RNF39 Human Proteome Map
InterPro B30.2/SPRY UniProtKB/Swiss-Prot
  B30.2/SPRY_sf UniProtKB/Swiss-Prot
  Butyrophylin_SPRY UniProtKB/Swiss-Prot
1 to 40 of 93 rows