SCARB1 (scavenger receptor class B member 1) - Rat Genome Database
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Gene: SCARB1 (scavenger receptor class B member 1) Homo sapiens
Analyze
Symbol: SCARB1
Name: scavenger receptor class B member 1
RGD ID: 735633
HGNC Page HGNC
Description: Exhibits several functions, including apolipoprotein A-I binding activity; high-density lipoprotein particle receptor activity; and lipopolysaccharide binding activity. Involved in several processes, including detection of lipopolysaccharide; high-density lipoprotein particle clearance; and lipid transport. Localizes to lysosome and plasma membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CD36 and LIMPII analogous 1; CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 1; CD36 antigen-like 1; CD36L1; CLA-1; CLA1; collagen type I receptor, thrombospondin receptor-like 1; HDLQTL6; MGC138242; scavenger receptor class B type 1; scavenger receptor class B type III; scavenger receptor class B, member 1; SR-BI; SRB1
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Related Pseudogenes: LOC100420955  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl12124,776,856 - 124,882,668 (-)EnsemblGRCh38hg38GRCh38
GRCh3812124,776,856 - 124,863,864 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3712125,261,402 - 125,348,410 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3612123,828,127 - 123,914,472 (-)NCBINCBI36hg18NCBI36
Build 3412123,787,055 - 123,873,214NCBI
Celera12124,862,283 - 124,949,187 (-)NCBI
Cytogenetic Map12q24.31NCBI
HuRef12122,224,152 - 122,310,029 (-)NCBIHuRef
CHM1_112125,083,775 - 125,169,604 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-catechin  (EXP)
(+)-schisandrin B  (ISO)
(S)-nicotine  (EXP,ISO)
1,2-dichloroethane  (ISO)
1-naphthyl isothiocyanate  (EXP)
14-Deoxy-11,12-didehydroandrographolide  (EXP)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4-dinitrotoluene  (ISO)
2-methoxyethanol  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
4-hydroxynon-2-enal  (EXP)
7,12-dimethyltetraphene  (ISO)
8-Br-cAMP  (EXP)
9-cis-retinoic acid  (EXP)
acetylsalicylic acid  (EXP,ISO)
aconitine  (ISO)
acrylamide  (ISO)
aflatoxin B1  (EXP)
all-trans-retinoic acid  (EXP,ISO)
all-trans-retinyl palmitate  (ISO)
aluminium oxide  (EXP)
ammonium chloride  (ISO)
androgen antagonist  (ISO)
Aroclor 1254  (ISO)
arsane  (EXP)
arsenic atom  (EXP)
atorvastatin calcium  (EXP)
atrazine  (ISO)
benzo[a]pyrene  (EXP,ISO)
beta-carotene  (EXP)
bifenthrin  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bromocriptine  (ISO)
bucladesine  (ISO)
buspirone  (ISO)
Butylbenzyl phthalate  (ISO)
caffeine  (ISO)
carbon nanotube  (ISO)
chenodeoxycholic acid  (EXP)
chloroquine  (ISO)
cholesterol  (ISO)
cholic acid  (ISO)
choline  (ISO)
cisplatin  (EXP,ISO)
clofibrate  (ISO)
clofibric acid  (ISO)
cobalt dichloride  (EXP)
cocaine  (EXP)
copper atom  (EXP)
copper(0)  (EXP)
copper(II) sulfate  (EXP)
cortisol  (EXP)
coumestrol  (EXP)
curcumin  (ISO)
cyclosporin A  (EXP)
cyhalothrin  (ISO)
cyproconazole  (ISO)
DDT  (ISO)
decabromodiphenyl ether  (ISO)
deoxycholic acid  (EXP)
dexamethasone  (ISO)
Di-n-hexyl phthalate  (ISO)
diazinon  (EXP)
dibenziodolium  (EXP)
dibutyl phthalate  (EXP,ISO)
dicrotophos  (EXP)
Dicyclohexyl phthalate  (ISO)
diethyl phthalate  (ISO)
diheptyl phthalate  (ISO)
diisobutyl phthalate  (ISO)
diisononyl phthalate  (ISO)
Dimethyl phthalate  (ISO)
dipentyl phthalate  (ISO)
disodium selenite  (EXP)
diuron  (ISO)
dorsomorphin  (EXP)
Enterolactone  (EXP)
entinostat  (EXP)
ethanol  (EXP,ISO)
ezetimibe  (EXP)
fenofibrate  (EXP,ISO)
flavonoids  (ISO)
folic acid  (ISO)
fructose  (ISO)
genistein  (ISO)
glafenine  (ISO)
glycochenodeoxycholic acid  (EXP)
glycocholic acid  (EXP)
glycodeoxycholic acid  (EXP)
GW 3965  (EXP)
GW 4064  (EXP,ISO)
hexaconazole  (ISO)
high-density lipoprotein cholesterol  (EXP,ISO)
hydrogen peroxide  (EXP)
iron trichloride  (ISO)
kojic acid  (ISO)
L-methionine  (ISO)
lead diacetate  (ISO)
lead(0)  (EXP)
lead(2+)  (EXP)
leflunomide  (ISO)
lipopolysaccharide  (ISO)
lithocholic acid  (EXP,ISO)
losartan  (ISO)
lovastatin  (ISO)
mercury atom  (EXP)
mercury(0)  (EXP)
methoxychlor  (ISO)
methyl methanesulfonate  (EXP)
methyltestosterone  (EXP)
Mezerein  (ISO)
mifepristone  (EXP)
mono(2-ethylhexyl) phthalate  (ISO)
monocrotophos  (ISO)
monosodium L-glutamate  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (EXP)
N-nitrosodiethylamine  (ISO)
N-tosyl-L-phenylalanyl chloromethyl ketone  (ISO)
nefazodone  (EXP)
nickel atom  (EXP)
nicotine  (EXP,ISO)
nicotinic acid  (EXP,ISO)
obeticholic acid  (EXP)
okadaic acid  (ISO)
oxaliplatin  (ISO)
paracetamol  (EXP)
paraquat  (ISO)
pentachlorophenol  (ISO)
perfluorododecanoic acid  (ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (EXP,ISO)
phencyclidine  (EXP)
phenobarbital  (ISO)
phenytoin  (ISO)
PhIP  (ISO)
pioglitazone  (ISO)
pirinixic acid  (ISO)
potassium chromate  (EXP)
potassium dichromate  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
progesterone  (ISO)
propiconazole  (ISO)
resveratrol  (EXP,ISO)
rifampicin  (EXP)
rimonabant  (ISO)
ritonavir  (EXP)
Ro 31-8220  (EXP)
rotenone  (ISO)
saccharin  (ISO)
SB 431542  (EXP)
Se-methyl-L-selenocysteine  (EXP)
Se-methylselenocysteine  (EXP)
selenomethionine  (EXP)
silver atom  (ISO)
silver(0)  (ISO)
simvastatin  (EXP,ISO)
sodium arsenite  (ISO)
sodium dichromate  (ISO)
Sodium salicylate  (EXP)
sucrose  (ISO)
sulfadimethoxine  (ISO)
sulpiride  (ISO)
testosterone enanthate  (ISO)
tetrachloromethane  (ISO)
tin(II) chloride (anhydrous)  (ISO)
titanium dioxide  (ISO)
topotecan  (ISO)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
triphenylstannane  (ISO)
troglitazone  (ISO)
undecane  (ISO)
valproic acid  (EXP,ISO)
vecuronium bromide  (EXP)
vinclozolin  (ISO)
zinc dichloride  (ISO)
ziram  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:1076467   PMID:4838888   PMID:7539776   PMID:7689561   PMID:9211901   PMID:10764676   PMID:10829064   PMID:11196441   PMID:11208913   PMID:11238031   PMID:11240025   PMID:11575708  
PMID:11792700   PMID:11944916   PMID:11952809   PMID:12016218   PMID:12039952   PMID:12100619   PMID:12119305   PMID:12138091   PMID:12164779   PMID:12202492   PMID:12207878   PMID:12227853  
PMID:12356718   PMID:12417285   PMID:12477932   PMID:12519372   PMID:12555245   PMID:12562842   PMID:12568179   PMID:12651854   PMID:12663276   PMID:12763030   PMID:12788901   PMID:12807968  
PMID:12913001   PMID:12966036   PMID:12968020   PMID:14551195   PMID:14566094   PMID:14652019   PMID:14676281   PMID:14701812   PMID:14718538   PMID:14726519   PMID:14967816   PMID:15072554  
PMID:15102890   PMID:15166784   PMID:15186961   PMID:15226391   PMID:15342124   PMID:15345670   PMID:15489334   PMID:15492319   PMID:15509885   PMID:15561721   PMID:15576377   PMID:15632171  
PMID:15681296   PMID:15749707   PMID:15910850   PMID:15970294   PMID:15979078   PMID:16120612   PMID:16168958   PMID:16185081   PMID:16380385   PMID:16410457   PMID:16476701   PMID:16488891  
PMID:16542392   PMID:16574909   PMID:16600224   PMID:16675450   PMID:16770077   PMID:16777453   PMID:16794223   PMID:16816107   PMID:16870193   PMID:16926440   PMID:17105723   PMID:17110915  
PMID:17215280   PMID:17240192   PMID:17241464   PMID:17259591   PMID:17311943   PMID:17404186   PMID:17476110   PMID:17507483   PMID:17531953   PMID:17574123   PMID:17618962   PMID:17673517  
PMID:17700364   PMID:17784784   PMID:17897319   PMID:17905649   PMID:17957039   PMID:18007013   PMID:18053692   PMID:18057374   PMID:18216094   PMID:18285332   PMID:18373109   PMID:18403724  
PMID:18424859   PMID:18477479   PMID:18542840   PMID:18640393   PMID:18641187   PMID:18660489   PMID:18676680   PMID:18757346   PMID:18779053   PMID:18779054   PMID:18829747   PMID:18930459  
PMID:18981156   PMID:19087225   PMID:19094442   PMID:19136670   PMID:19148942   PMID:19156545   PMID:19158204   PMID:19169357   PMID:19170196   PMID:19179658   PMID:19229312   PMID:19276229  
PMID:19489872   PMID:19497383   PMID:19620049   PMID:19625176   PMID:19689828   PMID:19692168   PMID:19718657   PMID:19776133   PMID:19806217   PMID:19828610   PMID:19837407   PMID:19878569  
PMID:19913121   PMID:19948975   PMID:19996318   PMID:20031551   PMID:20032583   PMID:20057170   PMID:20060115   PMID:20064494   PMID:20085651   PMID:20156043   PMID:20160195   PMID:20167577  
PMID:20186155   PMID:20304957   PMID:20331378   PMID:20379614   PMID:20442857   PMID:20458337   PMID:20551015   PMID:20602615   PMID:20628086   PMID:20629037   PMID:20677014   PMID:20686565  
PMID:20713650   PMID:20718868   PMID:20724701   PMID:20734064   PMID:20835684   PMID:20844007   PMID:20855565   PMID:20949066   PMID:20962076   PMID:21131975   PMID:21145461   PMID:21226579  
PMID:21289254   PMID:21454568   PMID:21454587   PMID:21480869   PMID:21481393   PMID:21485189   PMID:21512283   PMID:21525007   PMID:21531995   PMID:21551950   PMID:21729881   PMID:21873635  
PMID:21917726   PMID:22025344   PMID:22097902   PMID:22178419   PMID:22182283   PMID:22262054   PMID:22268729   PMID:22390933   PMID:22425645   PMID:22442701   PMID:22503545   PMID:22579005  
PMID:22583964   PMID:22614118   PMID:22628436   PMID:22767607   PMID:23023567   PMID:23029167   PMID:23041084   PMID:23091409   PMID:23109900   PMID:23118302   PMID:23133640   PMID:23175350  
PMID:23192982   PMID:23402987   PMID:23403740   PMID:23510561   PMID:23562302   PMID:23698298   PMID:23711372   PMID:23812625   PMID:23843895   PMID:23852455   PMID:23919842   PMID:24097068  
PMID:24151447   PMID:24257605   PMID:24376512   PMID:24423486   PMID:24529115   PMID:24549717   PMID:24738490   PMID:24854385   PMID:24969774   PMID:24990994   PMID:25142595   PMID:25181357  
PMID:25228690   PMID:25245032   PMID:25416956   PMID:25468996   PMID:25528585   PMID:25600616   PMID:25656410   PMID:25766837   PMID:25833688   PMID:25932604   PMID:25945350   PMID:25993026  
PMID:26006105   PMID:26186194   PMID:26322417   PMID:26334034   PMID:26381674   PMID:26431876   PMID:26439863   PMID:26454245   PMID:26456958   PMID:26511855   PMID:26563154   PMID:26571379  
PMID:26577021   PMID:26602218   PMID:26638075   PMID:26754576   PMID:26871637   PMID:26936883   PMID:26964503   PMID:26965621   PMID:27067809   PMID:27207655   PMID:27225585   PMID:27320013  
PMID:27377933   PMID:27428740   PMID:27561198   PMID:27630236   PMID:27651445   PMID:27666478   PMID:27865981   PMID:27881715   PMID:28061439   PMID:28181168   PMID:28298427   PMID:28360088  
PMID:28363797   PMID:28373285   PMID:28466781   PMID:28514442   PMID:28552715   PMID:28611215   PMID:28685749   PMID:28811710   PMID:28827115   PMID:28882953   PMID:28882954   PMID:28888368  
PMID:28941732   PMID:28947101   PMID:28974560   PMID:29102450   PMID:29117863   PMID:29128352   PMID:29180619   PMID:29196159   PMID:29277016   PMID:29357836   PMID:29407889   PMID:29481863  
PMID:29507755   PMID:29516118   PMID:29568061   PMID:29596577   PMID:29715527   PMID:29853565   PMID:29865042   PMID:30024968   PMID:30059777   PMID:30103009   PMID:30194290   PMID:30289950  
PMID:30639242   PMID:30823658   PMID:30837308   PMID:30876920   PMID:31019307   PMID:31064850   PMID:31251897   PMID:31280863   PMID:31358896   PMID:31536960   PMID:32353859   PMID:32369415  
PMID:32782257   PMID:32788342   PMID:32814053   PMID:32900848   PMID:33060197   PMID:33144569  


Genomics

Candidate Gene Status
SCARB1 is a candidate Gene for QTL BW451_H
SCARB1 is a candidate Gene for QTL BW500_H
SCARB1 is a candidate Gene for QTL BW501_H
SCARB1 is a candidate Gene for QTL BW502_H
Comparative Map Data
SCARB1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl12124,776,856 - 124,882,668 (-)EnsemblGRCh38hg38GRCh38
GRCh3812124,776,856 - 124,863,864 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3712125,261,402 - 125,348,410 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3612123,828,127 - 123,914,472 (-)NCBINCBI36hg18NCBI36
Build 3412123,787,055 - 123,873,214NCBI
Celera12124,862,283 - 124,949,187 (-)NCBI
Cytogenetic Map12q24.31NCBI
HuRef12122,224,152 - 122,310,029 (-)NCBIHuRef
CHM1_112125,083,775 - 125,169,604 (-)NCBICHM1_1
Scarb1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395125,354,151 - 125,418,158 (-)NCBIGRCm39mm39
GRCm39 Ensembl5125,354,151 - 125,418,158 (-)Ensembl
GRCm385125,277,087 - 125,341,094 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5125,277,087 - 125,341,094 (-)EnsemblGRCm38mm10GRCm38
MGSCv375125,757,460 - 125,821,444 (-)NCBIGRCm37mm9NCBIm37
MGSCv365125,566,069 - 125,630,053 (-)NCBImm8
Celera5122,296,944 - 122,361,197 (-)NCBICelera
Cytogenetic Map5G1.1NCBI
cM Map564.11NCBI
Scarb1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21231,296,143 - 31,362,649 (+)NCBI
Rnor_6.0 Ensembl1236,694,960 - 36,761,455 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01236,694,952 - 36,761,445 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01238,572,152 - 38,638,465 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41232,390,183 - 32,457,661 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11232,253,570 - 32,321,047 (+)NCBI
Celera1232,988,597 - 33,054,666 (+)NCBICelera
Cytogenetic Map12q15NCBI
Scarb1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554824,813,955 - 4,837,392 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554824,813,502 - 4,836,479 (+)NCBIChiLan1.0ChiLan1.0
SCARB1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.112126,651,077 - 126,698,506 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12126,659,532 - 126,694,767 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v012122,293,803 - 122,455,314 (-)NCBIMhudiblu_PPA_v0panPan3
SCARB1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl265,049,407 - 5,121,468 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1265,035,797 - 5,122,383 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Scarb1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_004936558530,828 - 555,098 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SCARB1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1428,301,294 - 28,393,565 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11428,301,421 - 28,393,568 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21430,050,898 - 30,093,735 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SCARB1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.111120,134,485 - 120,223,512 (-)NCBI
ChlSab1.1 Ensembl11120,134,874 - 120,216,904 (-)Ensembl
Scarb1
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474723,970,782 - 24,010,683 (-)NCBI

Position Markers
RH11185  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3712125,262,253 - 125,262,451UniSTSGRCh37
Build 3612123,828,206 - 123,828,404RGDNCBI36
Celera12124,862,362 - 124,862,560RGD
Cytogenetic Map12q24.31UniSTS
HuRef12122,224,231 - 122,224,429UniSTS
GeneMap99-GB4 RH Map12484.91UniSTS
NCBI RH Map12779.6UniSTS
SHGC-84469  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3712125,294,290 - 125,294,588UniSTSGRCh37
Build 3612123,860,243 - 123,860,541RGDNCBI36
Celera12124,894,410 - 124,894,708RGD
Cytogenetic Map12q24.31UniSTS
HuRef12122,255,852 - 122,256,150UniSTS
TNG Radiation Hybrid Map1261591.0UniSTS
TNG Radiation Hybrid Map1261597.0UniSTS
G59354  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3712125,293,792 - 125,294,075UniSTSGRCh37
Build 3612123,859,745 - 123,860,028RGDNCBI36
Celera12124,893,912 - 124,894,195RGD
Cytogenetic Map12q24.31UniSTS
HuRef12122,255,354 - 122,255,637UniSTS
TNG Radiation Hybrid Map1261591.0UniSTS
G64578  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3712125,304,079 - 125,304,360UniSTSGRCh37
Build 3612123,870,032 - 123,870,313RGDNCBI36
Celera12124,904,191 - 124,904,472RGD
Cytogenetic Map12q24.31UniSTS
HuRef12122,265,633 - 122,265,914UniSTS
SHGC-111902  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3712125,304,697 - 125,304,970UniSTSGRCh37
Build 3612123,870,650 - 123,870,923RGDNCBI36
Celera12124,904,809 - 124,905,082RGD
Cytogenetic Map12q24.31UniSTS
HuRef12122,266,251 - 122,266,524UniSTS
TNG Radiation Hybrid Map1261585.0UniSTS
SCARB1_2043  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3712125,261,981 - 125,262,873UniSTSGRCh37
Build 3612123,827,934 - 123,828,826RGDNCBI36
Celera12124,862,090 - 124,862,982RGD
HuRef12122,223,959 - 122,224,851UniSTS
RH64878  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3712125,272,296 - 125,272,416UniSTSGRCh37
Build 3612123,838,249 - 123,838,369RGDNCBI36
Celera12124,872,407 - 124,872,527RGD
Cytogenetic Map12q24.31UniSTS
HuRef12122,234,277 - 122,234,397UniSTS
GeneMap99-GB4 RH Map12484.7UniSTS
A009B29  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3712125,274,014 - 125,274,133UniSTSGRCh37
Build 3612123,839,967 - 123,840,086RGDNCBI36
Celera12124,874,125 - 124,874,244RGD
Cytogenetic Map12q24.31UniSTS
HuRef12122,235,995 - 122,236,114UniSTS
GeneMap99-GB4 RH Map12479.13UniSTS
NCBI RH Map12776.8UniSTS
RH46525  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3712125,329,534 - 125,329,672UniSTSGRCh37
Build 3612123,895,487 - 123,895,625RGDNCBI36
Celera12124,930,194 - 124,930,332RGD
Cytogenetic Map12q24.31UniSTS
HuRef12122,291,041 - 122,291,179UniSTS
GeneMap99-GB4 RH Map12487.23UniSTS
NCBI RH Map12779.6UniSTS
UniSTS:66150  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3712125,262,244 - 125,262,354UniSTSGRCh37
Build 3612123,828,197 - 123,828,307RGDNCBI36
Celera12124,862,353 - 124,862,463RGD
HuRef12122,224,222 - 122,224,332UniSTS
G32387  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3712125,274,014 - 125,274,133UniSTSGRCh37
Celera12124,874,125 - 124,874,244UniSTS
Cytogenetic Map12q24.31UniSTS
HuRef12122,235,995 - 122,236,114UniSTS
D11S3316  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map6p21UniSTS
Cytogenetic Map16q24UniSTS
Cytogenetic Map12q24.31UniSTS
Cytogenetic Map14q23.3UniSTS
Cytogenetic Map22q13.1UniSTS
Cytogenetic Map16p13.3UniSTS
Cytogenetic Map17q22UniSTS
Cytogenetic Map17p13.1UniSTS
Cytogenetic Map5q33.3UniSTS
Cytogenetic Map10q11.1UniSTS
Cytogenetic MapXp11.4UniSTS
Cytogenetic Map1q23.1UniSTS
Cytogenetic Map10q22UniSTS
Cytogenetic Map2q31.1UniSTS
Cytogenetic Map3q21.3UniSTS
Cytogenetic Map7p15-p14UniSTS
Cytogenetic Map2p11.2UniSTS
Cytogenetic Map4p12UniSTS
Cytogenetic Map1q42.1UniSTS
Cytogenetic Map16q22.1UniSTS
Cytogenetic Map18q11.2UniSTS
Cytogenetic Map11q24.2UniSTS
Cytogenetic Map7q22.1UniSTS
Cytogenetic Map2p12-p11.2UniSTS
Cytogenetic Map19q13.3UniSTS
Cytogenetic MapXp22UniSTS
Cytogenetic Map11q23.3UniSTS
Cytogenetic Map11q13.2UniSTS
Cytogenetic Map11q13UniSTS
Cytogenetic Map12q13-q14UniSTS
Cytogenetic Map8p11.22UniSTS
Cytogenetic Map1q32UniSTS
Cytogenetic Map11q12-q13.2UniSTS
Cytogenetic Map1p34UniSTS
Cytogenetic Map20p13UniSTS
Cytogenetic Map12q22UniSTS
Cytogenetic Map1p36.32UniSTS
Cytogenetic Map20q13.13UniSTS
Cytogenetic Map6q22.31UniSTS
Cytogenetic Map2q11.2UniSTS
Cytogenetic Map1p21UniSTS
Cytogenetic Map11q22.3UniSTS
Cytogenetic Map16q12.2UniSTS
Cytogenetic Map19q13.32UniSTS
Cytogenetic Map4q31.3UniSTS
Cytogenetic Map20q13.1UniSTS
Cytogenetic Map16p11.2UniSTS
Cytogenetic Map12q13.11-q14.3UniSTS
Cytogenetic Map3q13.33UniSTS
Cytogenetic Map6p22.2UniSTS
Cytogenetic Map3q26.33UniSTS
Cytogenetic Map6p21.3UniSTS
Cytogenetic Map8q24.11UniSTS
Cytogenetic Map15q13.1UniSTS
Cytogenetic Map10q22.2UniSTS
Cytogenetic Map2p14UniSTS
Cytogenetic Map15q11.2UniSTS
Cytogenetic Map19q13.12UniSTS
Cytogenetic Map7q11.23UniSTS
Cytogenetic Map11p15.5UniSTS
Cytogenetic Map9q33.3UniSTS
Cytogenetic MapXq24UniSTS
Cytogenetic Map17q25.3UniSTS
Cytogenetic Map10q26.13UniSTS
Cytogenetic Map19p13.3UniSTS
Cytogenetic Map16p13.2UniSTS
Cytogenetic Map15q14-q15UniSTS
Cytogenetic Map15q21.2UniSTS
Cytogenetic Map19q13UniSTS
Cytogenetic Map6p21.31UniSTS
Cytogenetic Map5q13UniSTS
Cytogenetic Map5q13.2UniSTS
Cytogenetic Map17q25.1UniSTS
Cytogenetic Map2p15UniSTS
Cytogenetic Map10q26.1UniSTS
Cytogenetic Map4q26UniSTS
Cytogenetic Map1q25.2UniSTS
Cytogenetic Map4q21.1UniSTS
Cytogenetic Map22q11.23UniSTS
Cytogenetic Map19p13.2UniSTS
Cytogenetic Map15q25.2UniSTS
Cytogenetic Map13q13.1UniSTS
Cytogenetic Map6p21.2UniSTS
Cytogenetic Map11q13.1UniSTS
Cytogenetic Map16p12.2UniSTS
Cytogenetic Map13q14UniSTS
Cytogenetic Map7q21-q22UniSTS
Cytogenetic Map12qUniSTS
Cytogenetic Map10q11.23UniSTS
Cytogenetic Map1p34.1UniSTS
Cytogenetic Map3p21.31UniSTS
Cytogenetic Map14q31UniSTS
GDB:228077  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map12q24.31UniSTS
fe49f02.x1  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3712125,305,787 - 125,307,131UniSTSGRCh37
Celera12124,905,895 - 124,907,239UniSTS
HuRef12122,267,337 - 122,268,681UniSTS

miRNA Target Status

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
MIR96hsa-miR-96-5pMirtarbaseexternal_infoLuciferase reporter assayFunctional MTI23459944
MIR185hsa-miR-185-5pMirtarbaseexternal_infoLuciferase reporter assayFunctional MTI23459944
MIR223hsa-miR-223-3pMirtarbaseexternal_infoLuciferase reporter assayFunctional MTI23459944

Predicted Target Of
Summary Value
Count of predictions:5545
Count of miRNA genes:1003
Interacting mature miRNAs:1207
Transcripts:ENST00000261693, ENST00000339570, ENST00000376788, ENST00000415380, ENST00000535005, ENST00000538291, ENST00000539320, ENST00000540495, ENST00000541205, ENST00000541661, ENST00000544327, ENST00000545305, ENST00000545493, ENST00000546215
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High 91
Medium 1320 589 1543 605 1022 457 3117 527 3509 214 1389 1398 162 1 1204 1556 3 2
Low 1119 2381 92 19 860 8 1240 1668 225 205 71 215 13 1232 3
Below cutoff 21 68 2

Sequence

Nucleotide Sequences
RefSeq Transcripts NG_028199 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001082959 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001367981 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001367982 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001367983 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001367984 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001367985 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001367986 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001367987 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001367988 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001367989 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_005505 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_160416 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_160417 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_160418 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_160419 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_160420 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_160421 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_160422 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_160423 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_160424 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB209436 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC073593 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC126309 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF254409 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF515445 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK124112 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK302779 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK304730 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC022087 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC034322 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC080647 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC093732 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC112037 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC143319 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BG770204 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CA428516 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471054 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KU177964 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KU177965 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Z22555 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000261693   ⟹   ENSP00000261693
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl12124,776,856 - 124,863,864 (-)Ensembl
RefSeq Acc Id: ENST00000339570   ⟹   ENSP00000343795
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl12124,776,856 - 124,863,917 (-)Ensembl
RefSeq Acc Id: ENST00000415380   ⟹   ENSP00000414979
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl12124,777,633 - 124,863,846 (-)Ensembl
RefSeq Acc Id: ENST00000535005
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl12124,782,683 - 124,880,461 (-)Ensembl
RefSeq Acc Id: ENST00000538291
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl12124,778,278 - 124,863,863 (-)Ensembl
RefSeq Acc Id: ENST00000539320
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl12124,814,973 - 124,863,896 (-)Ensembl
RefSeq Acc Id: ENST00000541661
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl12124,814,964 - 124,882,668 (-)Ensembl
RefSeq Acc Id: ENST00000544327   ⟹   ENSP00000444851
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl12124,785,820 - 124,817,707 (-)Ensembl
RefSeq Acc Id: ENST00000545305
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl12124,777,873 - 124,786,493 (-)Ensembl
RefSeq Acc Id: ENST00000545493   ⟹   ENSP00000443454
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl12124,814,961 - 124,863,863 (-)Ensembl
RefSeq Acc Id: ENST00000546215   ⟹   ENSP00000442862
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl12124,778,499 - 124,863,783 (-)Ensembl
RefSeq Acc Id: ENST00000679605   ⟹   ENSP00000505370
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl12124,777,212 - 124,863,968 (-)Ensembl
RefSeq Acc Id: ENST00000679955
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl12124,785,756 - 124,802,975 (-)Ensembl
RefSeq Acc Id: ENST00000680556   ⟹   ENSP00000505757
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl12124,777,212 - 124,863,921 (-)Ensembl
RefSeq Acc Id: ENST00000680596   ⟹   ENSP00000505605
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl12124,777,212 - 124,863,865 (-)Ensembl
RefSeq Acc Id: ENST00000680926   ⟹   ENSP00000505571
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl12124,777,212 - 124,863,921 (-)Ensembl
RefSeq Acc Id: ENST00000680982   ⟹   ENSP00000506281
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl12124,777,212 - 124,863,896 (-)Ensembl
RefSeq Acc Id: ENST00000681117   ⟹   ENSP00000506693
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl12124,777,653 - 124,863,865 (-)Ensembl
RefSeq Acc Id: ENST00000681499
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl12124,777,701 - 124,815,271 (-)Ensembl
RefSeq Acc Id: ENST00000681555
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl12124,777,212 - 124,814,521 (-)Ensembl
RefSeq Acc Id: ENST00000681686   ⟹   ENSP00000505406
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl12124,777,212 - 124,863,953 (-)Ensembl
RefSeq Acc Id: ENST00000681788
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl12124,777,212 - 124,789,308 (-)Ensembl
RefSeq Acc Id: NM_001082959   ⟹   NP_001076428
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3812124,776,856 - 124,863,864 (-)NCBI
GRCh3712125,262,174 - 125,348,519 (-)ENTREZGENE
Build 3612123,828,127 - 123,914,472 (-)NCBI Archive
HuRef12122,224,152 - 122,310,029 (-)ENTREZGENE
CHM1_112125,083,775 - 125,169,604 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001367981   ⟹   NP_001354910
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3812124,776,856 - 124,863,864 (-)NCBI
RefSeq Acc Id: NM_001367982   ⟹   NP_001354911
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3812124,785,703 - 124,839,671 (-)NCBI
RefSeq Acc Id: NM_001367983   ⟹   NP_001354912
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3812124,776,856 - 124,863,864 (-)NCBI
RefSeq Acc Id: NM_001367984   ⟹   NP_001354913
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3812124,776,856 - 124,863,864 (-)NCBI
RefSeq Acc Id: NM_001367985   ⟹   NP_001354914
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3812124,776,856 - 124,863,864 (-)NCBI
RefSeq Acc Id: NM_001367986   ⟹   NP_001354915
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3812124,776,856 - 124,863,864 (-)NCBI
RefSeq Acc Id: NM_001367987   ⟹   NP_001354916
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3812124,776,856 - 124,863,864 (-)NCBI
RefSeq Acc Id: NM_001367988   ⟹   NP_001354917
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3812124,776,856 - 124,863,864 (-)NCBI
RefSeq Acc Id: NM_001367989   ⟹   NP_001354918
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3812124,776,856 - 124,863,864 (-)NCBI
RefSeq Acc Id: NM_005505   ⟹   NP_005496
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3812124,776,856 - 124,863,864 (-)NCBI
GRCh3712125,262,174 - 125,348,519 (-)ENTREZGENE
Build 3612123,828,127 - 123,914,472 (-)NCBI Archive
HuRef12122,224,152 - 122,310,029 (-)ENTREZGENE
CHM1_112125,083,775 - 125,169,604 (-)NCBI
Sequence:
RefSeq Acc Id: NR_160416
RefSeq Status: REVIEWED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3812124,776,856 - 124,863,864 (-)NCBI
RefSeq Acc Id: NR_160417
RefSeq Status: REVIEWED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3812124,776,856 - 124,863,864 (-)NCBI
RefSeq Acc Id: NR_160418
RefSeq Status: REVIEWED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3812124,776,856 - 124,863,864 (-)NCBI
RefSeq Acc Id: NR_160419
RefSeq Status: REVIEWED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3812124,776,856 - 124,863,864 (-)NCBI
RefSeq Acc Id: NR_160420
RefSeq Status: REVIEWED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3812124,776,856 - 124,863,864 (-)NCBI
RefSeq Acc Id: NR_160421
RefSeq Status: REVIEWED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3812124,776,856 - 124,863,864 (-)NCBI
RefSeq Acc Id: NR_160422
RefSeq Status: REVIEWED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3812124,776,856 - 124,863,864 (-)NCBI
RefSeq Acc Id: NR_160423
RefSeq Status: REVIEWED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3812124,776,856 - 124,863,864 (-)NCBI
RefSeq Acc Id: NR_160424
RefSeq Status: REVIEWED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3812124,776,856 - 124,863,864 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001076428 (Get FASTA)   NCBI Sequence Viewer  
  NP_001354910 (Get FASTA)   NCBI Sequence Viewer  
  NP_001354911 (Get FASTA)   NCBI Sequence Viewer  
  NP_001354912 (Get FASTA)   NCBI Sequence Viewer  
  NP_001354913 (Get FASTA)   NCBI Sequence Viewer  
  NP_001354914 (Get FASTA)   NCBI Sequence Viewer  
  NP_001354915 (Get FASTA)   NCBI Sequence Viewer  
  NP_001354916 (Get FASTA)   NCBI Sequence Viewer  
  NP_001354917 (Get FASTA)   NCBI Sequence Viewer  
  NP_001354918 (Get FASTA)   NCBI Sequence Viewer  
  NP_005496 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAF91347 (Get FASTA)   NCBI Sequence Viewer  
  AAH80647 (Get FASTA)   NCBI Sequence Viewer  
  AAH93732 (Get FASTA)   NCBI Sequence Viewer  
  AAI12038 (Get FASTA)   NCBI Sequence Viewer  
  AAI43320 (Get FASTA)   NCBI Sequence Viewer  
  AAQ08185 (Get FASTA)   NCBI Sequence Viewer  
  ALQ33422 (Get FASTA)   NCBI Sequence Viewer  
  ALQ33423 (Get FASTA)   NCBI Sequence Viewer  
  BAD92673 (Get FASTA)   NCBI Sequence Viewer  
  BAG54008 (Get FASTA)   NCBI Sequence Viewer  
  BAG63983 (Get FASTA)   NCBI Sequence Viewer  
  BAG65493 (Get FASTA)   NCBI Sequence Viewer  
  CAA80277 (Get FASTA)   NCBI Sequence Viewer  
  EAW98458 (Get FASTA)   NCBI Sequence Viewer  
  EAW98459 (Get FASTA)   NCBI Sequence Viewer  
  EAW98460 (Get FASTA)   NCBI Sequence Viewer  
  EAW98461 (Get FASTA)   NCBI Sequence Viewer  
  EAW98462 (Get FASTA)   NCBI Sequence Viewer  
  Q8WTV0 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001076428   ⟸   NM_001082959
- Peptide Label: isoform 2
- UniProtKB: Q8WTV0 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_005496   ⟸   NM_005505
- Peptide Label: isoform 1
- UniProtKB: Q8WTV0 (UniProtKB/Swiss-Prot),   A0A024RBS4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001354917   ⟸   NM_001367988
- Peptide Label: isoform 10
RefSeq Acc Id: NP_001354914   ⟸   NM_001367985
- Peptide Label: isoform 7
RefSeq Acc Id: NP_001354916   ⟸   NM_001367987
- Peptide Label: isoform 9
RefSeq Acc Id: NP_001354915   ⟸   NM_001367986
- Peptide Label: isoform 8
RefSeq Acc Id: NP_001354913   ⟸   NM_001367984
- Peptide Label: isoform 6
RefSeq Acc Id: NP_001354918   ⟸   NM_001367989
- Peptide Label: isoform 1
RefSeq Acc Id: NP_001354910   ⟸   NM_001367981
- Peptide Label: isoform 3
RefSeq Acc Id: NP_001354912   ⟸   NM_001367983
- Peptide Label: isoform 5
RefSeq Acc Id: NP_001354911   ⟸   NM_001367982
- Peptide Label: isoform 4
RefSeq Acc Id: ENSP00000444851   ⟸   ENST00000544327
RefSeq Acc Id: ENSP00000443454   ⟸   ENST00000545493
RefSeq Acc Id: ENSP00000442862   ⟸   ENST00000546215
RefSeq Acc Id: ENSP00000414979   ⟸   ENST00000415380
RefSeq Acc Id: ENSP00000343795   ⟸   ENST00000339570
RefSeq Acc Id: ENSP00000261693   ⟸   ENST00000261693
RefSeq Acc Id: ENSP00000506693   ⟸   ENST00000681117
RefSeq Acc Id: ENSP00000505571   ⟸   ENST00000680926
RefSeq Acc Id: ENSP00000506281   ⟸   ENST00000680982
RefSeq Acc Id: ENSP00000505605   ⟸   ENST00000680596
RefSeq Acc Id: ENSP00000505370   ⟸   ENST00000679605
RefSeq Acc Id: ENSP00000505406   ⟸   ENST00000681686
RefSeq Acc Id: ENSP00000505757   ⟸   ENST00000680556

Promoters
RGD ID:6810398
Promoter ID:HG_ACW:19653
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Lymphoblastoid
Transcripts:SCARB1.JAPR07-UNSPLICED
Position:
Human AssemblyChrPosition (strand)Source
Build 3612123,830,219 - 123,830,719 (-)MPROMDB
RGD ID:6789907
Promoter ID:HG_KWN:16996
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:K562
Transcripts:ENST00000339570
Position:
Human AssemblyChrPosition (strand)Source
Build 3612123,868,291 - 123,868,791 (-)MPROMDB
RGD ID:6790465
Promoter ID:HG_KWN:16997
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:ENST00000376788,   NM_001082959,   NM_005505,   UC001UGO.2,   UC001UGP.2
Position:
Human AssemblyChrPosition (strand)Source
Build 3612123,914,119 - 123,914,619 (-)MPROMDB
RGD ID:6852514
Promoter ID:EP74069
Type:initiation region
Name:HS_SCARB1
Description:Scavenger receptor class B, member 1.
SO ACC ID:SO:0000170
Source:EPD (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Mammalian gene collection (MGC) full-length cDNA cloning
Position:
Human AssemblyChrPosition (strand)Source
Build 3612123,914,346 - 123,914,406EPD
RGD ID:7225829
Promoter ID:EPDNEW_H18660
Type:initiation region
Name:SCARB1_2
Description:scavenger receptor class B member 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H18662  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh3812124,863,864 - 124,863,924EPDNEW

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
NM_005505.5(SCARB1):c.523A>G (p.Thr175Ala) single nucleotide variant High density lipoprotein cholesterol level quantitative trait locus 6 [RCV000032953] Chr12:124814309 [GRCh38]
Chr12:125298855 [GRCh37]
Chr12:12q24.31
association
NM_005505.5(SCARB1):c.335C>T (p.Ser112Phe) single nucleotide variant High density lipoprotein cholesterol level quantitative trait locus 6 [RCV000032954] Chr12:124815064 [GRCh38]
Chr12:125299610 [GRCh37]
Chr12:12q24.31
association
NM_005505.5(SCARB1):c.889C>T (p.Pro297Ser) single nucleotide variant High density lipoprotein cholesterol level quantitative trait locus 6 [RCV000023067] Chr12:124807881 [GRCh38]
Chr12:125292427 [GRCh37]
Chr12:12q24.31
association
GRCh38/hg38 12q24.23-24.33(chr12:118165459-133182322)x3 copy number gain See cases [RCV000050866] Chr12:118165459..133182322 [GRCh38]
Chr12:118603264..133758908 [GRCh37]
Chr12:117087647..132268981 [NCBI36]
Chr12:12q24.23-24.33
pathogenic
GRCh38/hg38 12q24.31-24.33(chr12:122985202-130714574)x1 copy number loss See cases [RCV000051345] Chr12:122985202..130714574 [GRCh38]
Chr12:123469749..131199119 [GRCh37]
Chr12:122035702..129765072 [NCBI36]
Chr12:12q24.31-24.33
pathogenic
GRCh38/hg38 12q24.31-24.33(chr12:123444758-133191400)x3 copy number gain See cases [RCV000051151] Chr12:123444758..133191400 [GRCh38]
Chr12:123929305..133767986 [GRCh37]
Chr12:122495258..132278059 [NCBI36]
Chr12:12q24.31-24.33
pathogenic
GRCh38/hg38 12q24.21-24.33(chr12:115131583-133166920)x3 copy number gain See cases [RCV000053689] Chr12:115131583..133166920 [GRCh38]
Chr12:115569388..133743506 [GRCh37]
Chr12:114053771..132253579 [NCBI36]
Chr12:12q24.21-24.33
pathogenic
GRCh38/hg38 12q24.23-24.33(chr12:119417382-133191400)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053691]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053691]|See cases [RCV000053691] Chr12:119417382..133191400 [GRCh38]
Chr12:119855187..133767986 [GRCh37]
Chr12:118339570..132278059 [NCBI36]
Chr12:12q24.23-24.33
pathogenic
GRCh38/hg38 12q24.31-24.33(chr12:123365769-133191400)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053693]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053693]|See cases [RCV000053693] Chr12:123365769..133191400 [GRCh38]
Chr12:123850316..133767986 [GRCh37]
Chr12:122416269..132278059 [NCBI36]
Chr12:12q24.31-24.33
pathogenic
GRCh38/hg38 12q24.31-24.33(chr12:123509825-133191400)x3 copy number gain See cases [RCV000135535] Chr12:123509825..133191400 [GRCh38]
Chr12:123994372..133767986 [GRCh37]
Chr12:122560325..132278059 [NCBI36]
Chr12:12q24.31-24.33
pathogenic
GRCh38/hg38 12q24.31-24.33(chr12:120697672-133202490)x3 copy number gain See cases [RCV000137651] Chr12:120697672..133202490 [GRCh38]
Chr12:121135475..133779076 [GRCh37]
Chr12:119619858..132289149 [NCBI36]
Chr12:12q24.31-24.33
pathogenic
GRCh38/hg38 12p13.33-q24.33(chr12:121271-133196807)x3 copy number gain See cases [RCV000139555] Chr12:121271..133196807 [GRCh38]
Chr12:282465..133773393 [GRCh37]
Chr12:100698..132283466 [NCBI36]
Chr12:12p13.33-q24.33
pathogenic
GRCh38/hg38 12q24.31-24.32(chr12:120718786-127500215)x1 copy number loss See cases [RCV000142454] Chr12:120718786..127500215 [GRCh38]
Chr12:121156589..127984760 [GRCh37]
Chr12:119640972..126550713 [NCBI36]
Chr12:12q24.31-24.32
pathogenic
GRCh38/hg38 12q24.31-24.32(chr12:121917758-127802717)x1 copy number loss See cases [RCV000143250] Chr12:121917758..127802717 [GRCh38]
Chr12:122355664..128287262 [GRCh37]
Chr12:120840047..126853215 [NCBI36]
Chr12:12q24.31-24.32
pathogenic
GRCh38/hg38 12q24.21-24.33(chr12:114268403-133201316)x3 copy number gain See cases [RCV000143656] Chr12:114268403..133201316 [GRCh38]
Chr12:114706208..133777902 [GRCh37]
Chr12:113190591..132287975 [NCBI36]
Chr12:12q24.21-24.33
pathogenic
Single allele duplication Preeclampsia [RCV000161688] Chr12:124776099..124836915 [GRCh38]
Chr12:125260645..125321461 [GRCh37]
Chr12:12q24.31
not provided
GRCh37/hg19 12p13.33-q24.33(chr12:1-133851895)x3 copy number gain See cases [RCV000258805] Chr12:1..133851895 [GRCh37]
Chr12:12p13.33-q24.33
pathogenic|likely pathogenic
GRCh37/hg19 12q24.31(chr12:125260645-125321461)x3 copy number gain Preeclampsia [RCV000161688]|Premature ovarian failure [RCV000225201] Chr12:125260645..125321461 [GRCh37]
Chr12:12q24.31
uncertain significance|not provided
NM_005505.5(SCARB1):c.1127C>T (p.Pro376Leu) single nucleotide variant High density lipoprotein cholesterol level quantitative trait locus 6 [RCV000239517] Chr12:124800125 [GRCh38]
Chr12:125284671 [GRCh37]
Chr12:12q24.31
pathogenic|association
NM_005505.5(SCARB1):c.1203-4C>A single nucleotide variant not provided [RCV000730091] Chr12:124787461 [GRCh38]
Chr12:125272007 [GRCh37]
Chr12:12q24.31
uncertain significance
GRCh37/hg19 12q24.31-24.32(chr12:122726807-127365912)x1 copy number loss See cases [RCV000449178] Chr12:122726807..127365912 [GRCh37]
Chr12:12q24.31-24.32
likely pathogenic
GRCh37/hg19 12p13.33-q24.33(chr12:173787-133777902)x3 copy number gain See cases [RCV000510482] Chr12:173787..133777902 [GRCh37]
Chr12:12p13.33-q24.33
pathogenic
GRCh37/hg19 12p13.33-q24.33(chr12:173787-133777902) copy number gain See cases [RCV000511643] Chr12:173787..133777902 [GRCh37]
Chr12:12p13.33-q24.33
pathogenic
GRCh37/hg19 12q24.31-24.32(chr12:125302399-126579875)x3 copy number gain not provided [RCV000683462] Chr12:125302399..126579875 [GRCh37]
Chr12:12q24.31-24.32
uncertain significance
GRCh37/hg19 12q24.23-24.33(chr12:120367241-133777645)x3 copy number gain not provided [RCV000738070] Chr12:120367241..133777645 [GRCh37]
Chr12:12q24.23-24.33
pathogenic
GRCh37/hg19 12p13.33-q24.33(chr12:191619-133777645)x3 copy number gain not provided [RCV000750246] Chr12:191619..133777645 [GRCh37]
Chr12:12p13.33-q24.33
pathogenic
GRCh37/hg19 12p13.33-q24.33(chr12:621220-133779118)x3 copy number gain not provided [RCV000750253] Chr12:621220..133779118 [GRCh37]
Chr12:12p13.33-q24.33
pathogenic
GRCh37/hg19 12q24.31(chr12:124958653-125267086)x3 copy number gain not provided [RCV000750600] Chr12:124958653..125267086 [GRCh37]
Chr12:12q24.31
benign
NM_005505.5(SCARB1):c.273C>A (p.Pro91=) single nucleotide variant not provided [RCV000927203] Chr12:124817561 [GRCh38]
Chr12:125302107 [GRCh37]
Chr12:12q24.31
likely benign
GRCh37/hg19 12q24.31(chr12:125061845-125390744)x3 copy number gain not provided [RCV001006540] Chr12:125061845..125390744 [GRCh37]
Chr12:12q24.31
uncertain significance
GRCh37/hg19 12q24.31-24.32(chr12:122169403-129084163)x1 copy number loss not provided [RCV000848395] Chr12:122169403..129084163 [GRCh37]
Chr12:12q24.31-24.32
pathogenic
NM_005505.5(SCARB1):c.63C>T (p.Cys21=) single nucleotide variant not provided [RCV000970878] Chr12:124863658 [GRCh38]
Chr12:125348204 [GRCh37]
Chr12:12q24.31
benign
NM_005505.5(SCARB1):c.276C>T (p.Tyr92=) single nucleotide variant not provided [RCV000893949] Chr12:124817558 [GRCh38]
Chr12:125302104 [GRCh37]
Chr12:12q24.31
likely benign

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:1664 AgrOrtholog
COSMIC SCARB1 COSMIC
Ensembl Genes ENSG00000073060 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSP00000261693 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000343795 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000414979 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000442862 ENTREZGENE, UniProtKB/TrEMBL
  ENSP00000443454 UniProtKB/TrEMBL
  ENSP00000444851 ENTREZGENE, UniProtKB/TrEMBL
  ENSP00000505757 ENTREZGENE
Ensembl Transcript ENST00000261693 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000339570 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000415380 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000544327 ENTREZGENE, UniProtKB/TrEMBL
  ENST00000545493 UniProtKB/TrEMBL
  ENST00000546215 ENTREZGENE, UniProtKB/TrEMBL
  ENST00000679605 ENTREZGENE
  ENST00000680556 ENTREZGENE
  ENST00000680926 ENTREZGENE
GTEx ENSG00000073060 GTEx
HGNC ID HGNC:1664 ENTREZGENE
Human Proteome Map SCARB1 Human Proteome Map
InterPro CD36/SCARB1/SNMP1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CD36_fam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:949 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 949 ENTREZGENE
OMIM 601040 OMIM
  610762 OMIM
PANTHER PTHR11923 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam CD36 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA97 PharmGKB
PRINTS CD36ANTIGEN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CD36FAMILY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A024RBS4 ENTREZGENE, UniProtKB/TrEMBL
  A0A0S2Z3I2_HUMAN UniProtKB/TrEMBL
  A0A0S2Z3N2_HUMAN UniProtKB/TrEMBL
  B7ZKQ9_HUMAN UniProtKB/TrEMBL
  F5H4X0_HUMAN UniProtKB/TrEMBL
  F5H5E8_HUMAN UniProtKB/TrEMBL
  Q8WTV0 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary F8W8N0 UniProtKB/Swiss-Prot
  Q14016 UniProtKB/Swiss-Prot
  Q52LZ5 UniProtKB/Swiss-Prot
  Q6KFX4 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-12-22 SCARB1  scavenger receptor class B member 1    scavenger receptor class B, member 1  Symbol and/or name change 5135510 APPROVED