GRIN2B (glutamate ionotropic receptor NMDA type subunit 2B) - Rat Genome Database

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Gene: GRIN2B (glutamate ionotropic receptor NMDA type subunit 2B) Homo sapiens
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Symbol: GRIN2B
Name: glutamate ionotropic receptor NMDA type subunit 2B
RGD ID: 731079
HGNC Page HGNC
Description: Enables NMDA glutamate receptor activity; glutamate-gated calcium ion channel activity; and glycine binding activity. Involved in calcium ion transmembrane import into cytosol and response to ethanol. Located in plasma membrane. Is integral component of plasma membrane. Part of NMDA selective glutamate receptor complex. Implicated in several diseases, including alcohol use disorder; autosomal dominant non-syndromic intellectual disability 6; bipolar disorder; developmental and epileptic encephalopathy 27; and neurodegenerative disease (multiple). Biomarker of Alzheimer's disease; temporal lobe epilepsy; and vascular dementia.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: DEE27; EIEE27; GluN2B; GluN2B(alt_5'UTR); glutamate [NMDA] receptor subunit epsilon-2; glutamate receptor ionotropic, NMDA 2B; glutamate receptor subunit epsilon-2; glutamate receptor, ionotropic, N-methyl D-aspartate 2B; hNR3; MGC142178; MGC142180; MRD6; N-methyl D-aspartate receptor subtype 2B; N-methyl-D-aspartate receptor subunit 3; NMDAR2B; NR2B; NR3
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1213,437,942 - 13,982,002 (-)EnsemblGRCh38hg38GRCh38
GRCh381213,537,337 - 13,982,012 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371213,690,271 - 14,134,536 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361213,605,411 - 14,024,319 (-)NCBINCBI36hg18NCBI36
Build 341213,605,410 - 14,024,319NCBI
Celera1218,858,978 - 19,277,660 (-)NCBI
Cytogenetic Map12p13.1NCBI
HuRef1213,479,858 - 13,898,402 (-)NCBIHuRef
CHM1_11213,679,406 - 14,098,101 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-pilocarpine  (ISO)
1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
17beta-estradiol 3-benzoate  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
3',5'-cyclic AMP  (EXP)
3,4-methylenedioxymethamphetamine  (ISO)
3,5,6-trichloro-2-pyridinol  (ISO)
3,5,6-trichloropyridine-2-one  (ISO)
3-phenoxybenzoic acid  (ISO)
4-[1-hydroxy-2-[4-(phenylmethyl)-1-piperidinyl]propyl]phenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-azacytidine  (ISO)
6-propyl-2-thiouracil  (ISO)
aflatoxin B1  (EXP)
aflatoxin B2  (EXP)
all-trans-retinoic acid  (EXP)
ammonium acetate  (ISO)
ammonium chloride  (ISO)
amphetamine  (ISO)
arsenite(3-)  (EXP,ISO)
atrazine  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[e]pyrene  (EXP)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
Butylbenzyl phthalate  (ISO)
Butylparaben  (ISO)
capsaicin  (ISO)
capsazepine  (ISO)
carbaryl  (ISO)
carbon dioxide  (ISO)
carbon nanotube  (ISO)
celecoxib  (ISO)
chaetocin  (ISO)
chloroquine  (ISO)
chlorpyrifos  (ISO)
choline  (ISO)
citalopram  (ISO)
clozapine  (ISO)
cocaine  (ISO)
colforsin daropate hydrochloride  (ISO)
crocidolite asbestos  (EXP)
cyhalothrin  (ISO)
cypermethrin  (ISO)
DDE  (ISO)
decabromodiphenyl ether  (ISO)
dexamethasone  (ISO)
dextran sulfate  (ISO)
dextromethorphan  (ISO)
diazinon  (ISO)
dibutyl phthalate  (ISO)
dieldrin  (ISO)
diethyl phthalate  (ISO)
Diisodecyl phthalate  (ISO)
diminazene diaceturate  (ISO)
dioxygen  (ISO)
dizocilpine maleate  (EXP,ISO)
endosulfan  (ISO)
enzacamene  (ISO)
epoxiconazole  (ISO)
ethanol  (ISO)
excitatory amino acid agonist  (EXP)
felbamate  (ISO)
Fluorocitric acid  (ISO)
folic acid  (ISO)
formaldehyde  (ISO)
fulvestrant  (ISO)
haloperidol  (ISO)
ionomycin  (ISO)
isoflurane  (ISO)
kainic acid  (ISO)
ketamine  (ISO)
L-ascorbic acid  (EXP)
lead diacetate  (ISO)
leflunomide  (EXP)
linuron  (ISO)
lipopolysaccharide  (ISO)
lipoteichoic acid  (ISO)
lithium atom  (ISO)
lithium hydride  (ISO)
lovastatin  (ISO)
magnesium atom  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
melamine  (ISO)
methamphetamine  (ISO)
methapyrilene  (EXP)
methylmercury chloride  (ISO)
morphine  (ISO)
N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide  (ISO)
N-acetyl-L-cysteine  (ISO)
nickel atom  (ISO)
nobiletin  (ISO)
notoginsenoside R1  (EXP)
NS-398  (ISO)
Ondansetron  (ISO)
oxidopamine  (ISO)
paclitaxel  (ISO)
paraquat  (ISO)
PCB138  (ISO)
pentobarbital  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
pirinixic acid  (ISO)
potassium dichromate  (ISO)
prochloraz  (ISO)
procymidone  (ISO)
pyridine  (ISO)
remifentanil  (ISO)
resveratrol  (ISO)
Rhynchophylline  (ISO)
rimonabant  (ISO)
sarin  (EXP)
sevoflurane  (ISO)
silver atom  (EXP)
silver(0)  (EXP)
sodium arsenite  (ISO)
sodium fluoride  (ISO)
spermine  (ISO)
sulfur dioxide  (ISO)
sulindac  (ISO)
sunitinib  (EXP)
testosterone  (ISO)
tetrodotoxin  (ISO)
thimerosal  (ISO)
titanium dioxide  (ISO)
toluene  (ISO)
tributylstannane  (ISO)
trimethyltin  (ISO)
triptonide  (ISO)
valproic acid  (EXP,ISO)
venlafaxine hydrochloride  (ISO)
vinclozolin  (ISO)
vorinostat  (ISO)
zinc atom  (ISO)
zinc dichloride  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
action potential  (ISO)
associative learning  (ISO)
behavioral fear response  (ISO)
behavioral response to pain  (ISO)
brain development  (NAS)
calcium ion transmembrane import into cytosol  (IDA,IMP)
calcium ion transport  (ISO)
calcium-mediated signaling  (IEA)
cation transport  (ISO)
cellular response to amino acid stimulus  (ISO)
cellular response to corticosterone stimulus  (ISO)
cellular response to curcumin  (ISO)
cellular response to dsRNA  (ISO)
cellular response to forskolin  (ISO)
cellular response to growth factor stimulus  (ISO)
cellular response to lipid  (ISO)
cellular response to magnesium starvation  (ISO)
cellular response to manganese ion  (ISO)
cellular response to organic cyclic compound  (ISO)
cerebral cortex development  (ISO)
chemical synaptic transmission  (ISO,TAS)
detection of mechanical stimulus involved in sensory perception of pain  (ISO)
excitatory chemical synaptic transmission  (NAS)
excitatory postsynaptic potential  (IBA,ISO)
fear response  (ISO)
glutamate receptor signaling pathway  (TAS)
hippocampus development  (ISO)
in utero embryonic development  (ISO)
ionotropic glutamate receptor signaling pathway  (IEA,ISO)
learning  (ISO)
learning or memory  (ISS)
long-term memory  (ISO)
long-term synaptic potentiation  (IBA,ISO)
memory  (ISO)
multicellular organismal response to stress  (ISO)
negative regulation of dendritic spine maintenance  (ISS)
NMDA selective glutamate receptor signaling pathway  (ISO)
positive regulation of cell death  (ISO)
positive regulation of cysteine-type endopeptidase activity  (ISS)
positive regulation of glutamate secretion  (ISO)
positive regulation of neuron death  (ISS)
positive regulation of synaptic transmission  (ISO)
protein heterotetramerization  (ISS)
receptor clustering  (ISO)
regulation of long-term neuronal synaptic plasticity  (ISO)
regulation of MAPK cascade  (ISO)
regulation of postsynaptic cytosolic calcium ion concentration  (ISO)
regulation of postsynaptic membrane potential  (ISO)
regulation of protein kinase A signaling  (ISO)
regulation of synaptic plasticity  (ISO,NAS)
response to amine  (ISO)
response to amphetamine  (ISO)
response to calcium ion  (ISO)
response to carbohydrate  (ISO)
response to cocaine  (ISO)
response to cytokine  (ISO)
response to electrical stimulus  (ISO)
response to ethanol  (IDA,ISO)
response to fungicide  (ISO)
response to growth hormone  (ISO)
response to hypoxia  (ISO)
response to magnesium ion  (ISO)
response to manganese ion  (ISO)
response to mechanical stimulus  (ISO)
response to methylmercury  (ISO)
response to organic cyclic compound  (ISO)
response to organonitrogen compound  (ISO)
response to other organism  (ISO)
response to toxic substance  (ISO)
rhythmic process  (ISO)
sensitization  (ISO)
sensory organ development  (ISO)
startle response  (ISO)
suckling behavior  (ISO)

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
Abnormal facial shape  (IAGP)
Abnormal hippocampus morphology  (IAGP)
Abnormality of skin morphology  (IAGP)
Abnormality of the curvature of the vertebral column  (IAGP)
Absent speech  (IAGP)
Astigmatism  (IAGP)
Ataxia  (IAGP)
Atonic seizure  (IAGP)
Autistic behavior  (IAGP)
Autosomal dominant inheritance  (IAGP)
Behavioral abnormality  (IAGP)
Bilateral generalized polymicrogyria  (IAGP)
Bilateral tonic-clonic seizure  (IAGP)
Cerebral atrophy  (IAGP)
Cerebral visual impairment  (IAGP)
Chorea  (IAGP)
Craniosynostosis  (IAGP)
Delayed speech and language development  (IAGP)
Developmental regression  (IAGP)
Difficulty walking  (IAGP)
Dilation of lateral ventricles  (IAGP)
Dyskinesia  (IAGP)
Dyssynergia  (IAGP)
Dystonia  (IAGP)
EEG abnormality  (IAGP)
Epileptic encephalopathy  (IAGP)
Epileptic spasm  (IAGP)
Eyelid myoclonus  (IAGP)
Focal emotional seizure with laughing  (IAGP)
Focal impaired awareness seizure  (IAGP)
Focal motor seizure  (IAGP)
Gastroesophageal reflux  (IAGP)
Gastrostomy tube feeding in infancy  (IAGP)
Generalized hypotonia  (IAGP)
Generalized myoclonic seizure  (IAGP)
Generalized tonic seizure  (IAGP)
Global developmental delay  (IAGP)
Hypoplasia of the corpus callosum  (IAGP)
Hypotonia  (IAGP)
Hypsarrhythmia  (IAGP)
Infantile spasms  (IAGP)
Intellectual disability  (IAGP)
Intellectual disability, mild  (IAGP)
Intellectual disability, moderate  (IAGP)
Intellectual disability, profound  (IAGP)
Intellectual disability, severe  (IAGP)
Intrauterine growth retardation  (IAGP)
Joint hypermobility  (IAGP)
Leukoencephalopathy  (IAGP)
Long fingers  (IAGP)
Microcephaly  (IAGP)
Motor delay  (IAGP)
Myoclonus  (IAGP)
Oculogyric crisis  (IAGP)
Oral-pharyngeal dysphagia  (IAGP)
Paroxysmal dystonia  (IAGP)
Poor speech  (IAGP)
Scoliosis  (IAGP)
Seizure  (IAGP)
Self-injurious behavior  (IAGP)
Severe muscular hypotonia  (IAGP)
Short stature  (IAGP)
Sleep disturbance  (IAGP)
Spasticity  (IAGP)
Status epilepticus  (IAGP)
Stereotypy  (IAGP)
Typical absence seizure  (IAGP)
Variable expressivity  (IAGP)
Widened subarachnoid space  (IAGP)
References

References - curated
1. Andreoli V, etal., J Neural Transm (Vienna). 2014 May;121(5):533-42. doi: 10.1007/s00702-013-1125-7. Epub 2013 Dec 1.
2. Anu J, etal., Eur J Pharmacol. 2010 Mar 25;630(1-3):61-8. Epub 2010 Jan 6.
3. Arning L, etal., Hum Genet. 2007 Sep;122(2):175-82. Epub 2007 Jun 14.
4. Arning L, etal., Neurogenetics. 2005 Feb;6(1):25-8. Epub 2004 Nov 17.
5. Bartlett TE, etal., Neuropharmacology. 2007 Jan;52(1):60-70. Epub 2006 Aug 10.
6. Borbely S, etal., Neuroscience. 2009 Mar 3;159(1):358-68. Epub 2008 Dec 27.
7. Coultrap SJ and Bayer KU, Trends Neurosci. 2012 Oct;35(10):607-18. doi: 10.1016/j.tins.2012.05.003. Epub 2012 Jun 19.
8. Dos-Anjos S, etal., Neuroscience. 2009 Dec 15;164(3):1119-26. Epub 2009 Sep 15.
9. Fan J, etal., Gastroenterology. 2009 May;136(5):1732-40.e3. Epub 2009 Feb 6.
10. Fan MM, etal., J Neurosci. 2007 Apr 4;27(14):3768-79.
11. Ferrier J, etal., PLoS One. 2013 Oct 30;8(10):e77828. doi: 10.1371/journal.pone.0077828. eCollection 2013.
12. Geng SJ, etal., Exp Neurol. 2010 Apr;222(2):256-66. Epub 2010 Jan 14.
13. GOA_HUMAN data from the GO Consortium
14. GrĂ¼nder T, etal., Vis Neurosci. 2001 Sep-Oct;18(5):781-7.
15. Gulchina Y, etal., J Neurochem. 2017 Nov;143(3):320-333. doi: 10.1111/jnc.14101. Epub 2017 Sep 5.
16. Huang P, etal., Nan Fang Yi Ke Da Xue Xue Bao. 2010 Apr;30(4):708-11.
17. Huo XL, etal., PLoS One. 2014 Apr 9;9(4):e94278. doi: 10.1371/journal.pone.0094278. eCollection 2014.
18. Ishihama K, etal., Arch Histol Cytol. 2005 Dec;68(4):321-35.
19. Jensen V, etal., Neuroscience. 2009 Jan 12;158(1):353-64. doi: 10.1016/j.neuroscience.2008.05.016. Epub 2008 May 21.
20. Jiang H and Jia J, Neurosci Lett. 2009 Feb 6;450(3):356-60. doi: 10.1016/j.neulet.2008.10.075. Epub 2008 Oct 25.
21. Jiang X, etal., Neurobiol Aging. 2015 Feb;36(2):867-76. doi: 10.1016/j.neurobiolaging.2014.10.018. Epub 2014 Oct 16.
22. Kim E, etal., Am J Physiol Regul Integr Comp Physiol. 2010 Jun;298(6):R1588-96. Epub 2010 Mar 17.
23. Kim JH, etal., Neurosci Res. 2006 Oct;56(2):220-3. Epub 2006 Sep 5.
24. Leuba G, etal., Curr Alzheimer Res. 2014 Jan;11(1):86-96.
25. Levenson JM, etal., Biochim Biophys Acta. 2008 Aug;1779(8):422-31. Epub 2008 Jan 12.
26. Lewis B, etal., Pharmacol Biochem Behav. 2012 Jan;100(3):545-53. doi: 10.1016/j.pbb.2011.10.013. Epub 2011 Oct 20.
27. Li D and He L, Genet Med. 2007 Jan;9(1):4-8.
28. Li R, etal., BMC Neurosci. 2007 Jul 26;8:55.
29. Lisman J, etal., Nat Rev Neurosci. 2012 Feb 15;13(3):169-82. doi: 10.1038/nrn3192.
30. Martucci L, etal., Schizophr Res. 2006 Jun;84(2-3):214-21. Epub 2006 Mar 20.
31. Martynyuk AE, etal., Mol Genet Metab. 2005 Dec;86 Suppl 1:S34-42. Epub 2005 Sep 8.
32. Mathern GW, etal., Epilepsy Res. 1998 Sep;32(1-2):154-71.
33. Mohamed NE, etal., J Alzheimers Dis. 2015;44(2):431-7. doi: 10.3233/JAD-141764.
34. Montori S, etal., Neurochem Int. 2010 Jul;56(8):878-85. Epub 2010 Mar 27.
35. Monyer H, etal., Science 1992 May 22;256(5060):1217-21.
36. OMIM Disease Annotation Pipeline
37. Online Mendelian Inheritance in Man, OMIM (TM).
38. Pipeline to import KEGG annotations from KEGG into RGD
39. Pipeline to import Pathway Interaction Database annotations from NCI into RGD
40. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
41. RGD automated import pipeline for gene-chemical interactions
42. RGD automated import pipeline for human HPO-to-gene-to-disease annotations
43. Schober ME, etal., Am J Physiol Regul Integr Comp Physiol. 2009 Mar;296(3):R681-92. Epub 2009 Jan 14.
44. Seripa D, etal., Dement Geriatr Cogn Disord. 2008;25(3):287-92. doi: 10.1159/000118634. Epub 2008 Feb 26.
45. Tunc-Ozcan E, etal., Alcohol Clin Exp Res. 2013 Nov;37(11):1986-95. doi: 10.1111/acer.12183. Epub 2013 Jun 13.
46. Wei B, etal., Brain Res. 2016 Jan 15;1631:157-64. doi: 10.1016/j.brainres.2015.11.041. Epub 2015 Dec 2.
47. Wernicke C, etal., Biol Psychiatry. 2003 Nov 1;54(9):922-8.
48. Zhang-James Y, etal., Dev Neurosci. 2012;34(2-3):218-27. Epub 2012 Jul 6.
Additional References at PubMed
PMID:7569905   PMID:7695237   PMID:7959773   PMID:7999784   PMID:8139656   PMID:8163463   PMID:8563977   PMID:8581564   PMID:8601796   PMID:8615909   PMID:8665664   PMID:8724036  
PMID:8768735   PMID:8780649   PMID:8804048   PMID:8821747   PMID:8822372   PMID:8845955   PMID:8940188   PMID:8955056   PMID:9009191   PMID:9231720   PMID:9278515   PMID:9326658  
PMID:9427503   PMID:9481670   PMID:9547169   PMID:9581762   PMID:9620694   PMID:9647694   PMID:9651389   PMID:9670010   PMID:9694809   PMID:9745929   PMID:9806853   PMID:10197777  
PMID:10341223   PMID:10373510   PMID:10381539   PMID:10448428   PMID:10458595   PMID:10479680   PMID:10480938   PMID:10485705   PMID:10488080   PMID:10555109   PMID:10620012   PMID:10748157  
PMID:10846184   PMID:10884433   PMID:11024032   PMID:11029657   PMID:11278603   PMID:11306676   PMID:11317224   PMID:11459059   PMID:11483648   PMID:11483655   PMID:11588171   PMID:11606043  
PMID:11679592   PMID:11723117   PMID:11799243   PMID:11807413   PMID:11844890   PMID:11897110   PMID:11937501   PMID:11956967   PMID:11979061   PMID:11997254   PMID:12082569   PMID:12127670  
PMID:12147342   PMID:12191494   PMID:12391275   PMID:12414113   PMID:12476325   PMID:12477932   PMID:12524444   PMID:12531901   PMID:12556902   PMID:12650977   PMID:12738960   PMID:12753378  
PMID:12775422   PMID:12815021   PMID:12824739   PMID:12857875   PMID:12890763   PMID:12893641   PMID:14622581   PMID:14644469   PMID:14662797   PMID:14702039   PMID:15030493   PMID:15083261  
PMID:15180478   PMID:15211626   PMID:15254094   PMID:15489334   PMID:15542698   PMID:15673434   PMID:15721239   PMID:15749123   PMID:15812607   PMID:15841096   PMID:15866054   PMID:15888440  
PMID:16120608   PMID:16266783   PMID:16289038   PMID:16332682   PMID:16380905   PMID:16436603   PMID:16481105   PMID:16489129   PMID:16697675   PMID:16766085   PMID:16870468   PMID:16990796  
PMID:17010153   PMID:17047094   PMID:17255096   PMID:17360663   PMID:17459877   PMID:17506933   PMID:17506987   PMID:17526495   PMID:17620329   PMID:17669510   PMID:17942280   PMID:17962190  
PMID:17997397   PMID:18007143   PMID:18068304   PMID:18233995   PMID:18445116   PMID:18583979   PMID:18606955   PMID:18836292   PMID:18976975   PMID:18991843   PMID:19005876   PMID:19011431  
PMID:19020013   PMID:19036954   PMID:19086053   PMID:19088076   PMID:19095845   PMID:19156168   PMID:19167335   PMID:19192303   PMID:19268276   PMID:19279257   PMID:19324536   PMID:19328558  
PMID:19336002   PMID:19350219   PMID:19367581   PMID:19453375   PMID:19487695   PMID:19523047   PMID:19526283   PMID:19562769   PMID:19591125   PMID:19605943   PMID:19726645   PMID:19734545  
PMID:19784770   PMID:19811606   PMID:19874574   PMID:20018661   PMID:20175224   PMID:20197096   PMID:20201926   PMID:20347576   PMID:20379614   PMID:20399867   PMID:20421849   PMID:20427279  
PMID:20438806   PMID:20464528   PMID:20468064   PMID:20537720   PMID:20537986   PMID:20848605   PMID:20859245   PMID:20869595   PMID:20882066   PMID:20890276   PMID:20939817   PMID:20945430  
PMID:20957330   PMID:21116278   PMID:21491143   PMID:21597037   PMID:21639937   PMID:21670103   PMID:21704719   PMID:21749895   PMID:21753020   PMID:21782286   PMID:21789901   PMID:21827795  
PMID:21873635   PMID:21919190   PMID:21948112   PMID:22114277   PMID:22116950   PMID:22142193   PMID:22326929   PMID:22433450   PMID:22479519   PMID:22484476   PMID:22552781   PMID:22578441  
PMID:22610100   PMID:22610502   PMID:22711533   PMID:22742935   PMID:22832729   PMID:22833210   PMID:22833681   PMID:22850629   PMID:22936815   PMID:22940423   PMID:22986046   PMID:23160955  
PMID:23201971   PMID:23229837   PMID:23267846   PMID:23271275   PMID:23284306   PMID:23377640   PMID:23621516   PMID:23648631   PMID:23660601   PMID:23665428   PMID:23718928   PMID:23840674  
PMID:23855403   PMID:23918416   PMID:24086760   PMID:24114429   PMID:24272827   PMID:24490167   PMID:24491052   PMID:24503147   PMID:24550280   PMID:24607229   PMID:24739951   PMID:24925192  
PMID:25052836   PMID:25241761   PMID:25292222   PMID:25426763   PMID:25431428   PMID:25467983   PMID:25486778   PMID:25585032   PMID:25613138   PMID:25656819   PMID:25660313   PMID:25683482  
PMID:25693086   PMID:25760043   PMID:25893192   PMID:25896831   PMID:26020650   PMID:26081945   PMID:26252487   PMID:26321256   PMID:26584860   PMID:26627941   PMID:26690829   PMID:26719327  
PMID:26771436   PMID:26819771   PMID:26875626   PMID:26876050   PMID:26884337   PMID:26912815   PMID:26919761   PMID:27040756   PMID:27179791   PMID:27199241   PMID:27240047   PMID:27394963  
PMID:27453061   PMID:27498914   PMID:27605359   PMID:27616045   PMID:27818011   PMID:27839871   PMID:27876882   PMID:28130356   PMID:28228639   PMID:28252572   PMID:28258362   PMID:28273943  
PMID:28283559   PMID:28303017   PMID:28377535   PMID:28378791   PMID:28439047   PMID:28558131   PMID:28608743   PMID:28636948   PMID:28858643   PMID:28900078   PMID:29321103   PMID:29368832  
PMID:29511171   PMID:29566979   PMID:29851452   PMID:29921740   PMID:29937144   PMID:30031924   PMID:30054528   PMID:30126976   PMID:30140987   PMID:30298963   PMID:30475886   PMID:30785307  
PMID:30987697   PMID:31429998   PMID:31548203   PMID:31807283   PMID:31957106   PMID:31957823   PMID:31981822   PMID:33025395   PMID:33037073   PMID:33237434   PMID:33976221   PMID:34100982  
PMID:34227748   PMID:34321660  


Genomics

Comparative Map Data
GRIN2B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1213,437,942 - 13,982,002 (-)EnsemblGRCh38hg38GRCh38
GRCh381213,537,337 - 13,982,012 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371213,690,271 - 14,134,536 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361213,605,411 - 14,024,319 (-)NCBINCBI36hg18NCBI36
Build 341213,605,410 - 14,024,319NCBI
Celera1218,858,978 - 19,277,660 (-)NCBI
Cytogenetic Map12p13.1NCBI
HuRef1213,479,858 - 13,898,402 (-)NCBIHuRef
CHM1_11213,679,406 - 14,098,101 (-)NCBICHM1_1
Grin2b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396135,690,219 - 136,150,658 (-)NCBIGRCm39mm39
GRCm39 Ensembl6135,690,231 - 136,150,509 (-)Ensembl
GRCm386135,713,221 - 136,173,615 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6135,713,233 - 136,173,511 (-)EnsemblGRCm38mm10GRCm38
MGSCv376135,679,813 - 136,123,529 (-)NCBIGRCm37mm9NCBIm37
MGSCv366135,697,791 - 136,009,994 (-)NCBImm8
Celera6138,678,301 - 139,123,902 (-)NCBICelera
Cytogenetic Map6G1NCBI
cM Map666.38NCBI
Grin2b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.24168,580,824 - 169,044,110 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl4168,599,546 - 169,042,279 (-)Ensembl
Rnor_6.04169,541,620 - 170,000,216 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4169,560,387 - 169,999,873 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04233,806,406 - 234,260,360 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44172,721,895 - 173,183,187 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14172,966,830 - 173,428,311 (-)NCBI
Celera4157,188,514 - 157,629,365 (-)NCBICelera
RH 3.4 Map41026.8RGD
Cytogenetic Map4q43NCBI
Grin2b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541310,376,597 - 10,779,145 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541310,358,931 - 10,780,004 (-)NCBIChiLan1.0ChiLan1.0
GRIN2B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11213,943,936 - 14,272,195 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1213,969,387 - 14,388,799 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01213,543,104 - 13,987,437 (-)NCBIMhudiblu_PPA_v0panPan3
GRIN2B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12732,470,889 - 32,883,606 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2732,471,153 - 32,877,680 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2713,572,169 - 13,850,223 (-)NCBI
ROS_Cfam_1.02732,702,956 - 33,191,598 (+)NCBI
UMICH_Zoey_3.12732,798,882 - 33,078,120 (+)NCBI
UNSW_CanFamBas_1.02732,748,401 - 33,027,217 (+)NCBI
UU_Cfam_GSD_1.02713,302,777 - 13,581,228 (-)NCBI
Grin2b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494593,677,907 - 94,094,419 (+)NCBI
SpeTri2.0NW_0049365873,406,055 - 3,806,956 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GRIN2B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl558,480,526 - 58,927,583 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1558,477,862 - 58,948,735 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2561,874,217 - 62,275,930 (+)NCBISscrofa10.2Sscrofa10.2susScr3
GRIN2B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11113,444,155 - 13,873,034 (-)NCBI
ChlSab1.1 Ensembl1113,456,968 - 13,873,202 (-)Ensembl
Vero_WHO_p1.0NW_02366606921,440,620 - 21,872,881 (+)NCBI
Grin2b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475224,008,520 - 24,480,834 (+)NCBI

Position Markers
SHGC-78950  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371213,877,013 - 13,877,298UniSTSGRCh37
Build 361213,768,280 - 13,768,565RGDNCBI36
Celera1219,021,587 - 19,021,872RGD
Cytogenetic Map12p12UniSTS
HuRef1213,642,405 - 13,642,690UniSTS
TNG Radiation Hybrid Map125364.0UniSTS
RH121528  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371214,023,369 - 14,023,668UniSTSGRCh37
Build 361213,914,636 - 13,914,935RGDNCBI36
Celera1219,167,976 - 19,168,275RGD
Cytogenetic Map12p12UniSTS
HuRef1213,788,700 - 13,788,999UniSTS
TNG Radiation Hybrid Map125391.0UniSTS
G60183  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371213,714,804 - 13,715,116UniSTSGRCh37
Build 361213,606,071 - 13,606,383RGDNCBI36
Celera1218,859,372 - 18,859,684RGD
Cytogenetic Map12p12UniSTS
HuRef1213,480,252 - 13,480,564UniSTS
TNG Radiation Hybrid Map125294.0UniSTS
G62303  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371214,039,978 - 14,040,185UniSTSGRCh37
Build 361213,931,245 - 13,931,452RGD