SGPP2 (sphingosine-1-phosphate phosphatase 2) - Rat Genome Database

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Gene: SGPP2 (sphingosine-1-phosphate phosphatase 2) Homo sapiens
Analyze
Symbol: SGPP2
Name: sphingosine-1-phosphate phosphatase 2
RGD ID: 1346522
HGNC Page HGNC
Description: Exhibits sphingosine-1-phosphate phosphatase activity. Involved in sphingosine metabolic process. Localizes to endoplasmic reticulum.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: FLJ39004; hSPP2; sphingosine 1-phosphate phosphohydrolase 2; sphingosine-1-phosphatase 2; sphingosine-1-phosphate phosphotase 2; SPP2; SPPase2
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2222,424,543 - 222,562,621 (+)EnsemblGRCh38hg38GRCh38
GRCh382222,423,988 - 222,562,621 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372223,288,707 - 223,427,340 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362222,997,566 - 223,131,861 (+)NCBINCBI36hg18NCBI36
Build 342223,114,826 - 223,249,122NCBI
Celera2217,107,484 - 217,191,808 (+)NCBI
Cytogenetic Map2q36.1NCBI
HuRef2215,143,345 - 215,277,358 (+)NCBIHuRef
CHM1_12223,295,733 - 223,430,117 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:8889548   PMID:12477932   PMID:14702039   PMID:17113265   PMID:21873635   PMID:22277765   PMID:23568457   PMID:24274704   PMID:27059959  


Genomics

Comparative Map Data
SGPP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2222,424,543 - 222,562,621 (+)EnsemblGRCh38hg38GRCh38
GRCh382222,423,988 - 222,562,621 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372223,288,707 - 223,427,340 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362222,997,566 - 223,131,861 (+)NCBINCBI36hg18NCBI36
Build 342223,114,826 - 223,249,122NCBI
Celera2217,107,484 - 217,191,808 (+)NCBI
Cytogenetic Map2q36.1NCBI
HuRef2215,143,345 - 215,277,358 (+)NCBIHuRef
CHM1_12223,295,733 - 223,430,117 (+)NCBICHM1_1
Sgpp2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39178,286,186 - 78,396,926 (+)NCBIGRCm39mm39
GRCm39 Ensembl178,286,982 - 78,396,926 (+)Ensembl
GRCm38178,309,549 - 78,420,289 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl178,310,345 - 78,420,289 (+)EnsemblGRCm38mm10GRCm38
MGSCv37178,306,921 - 78,416,861 (+)NCBIGRCm37mm9NCBIm37
MGSCv36178,193,492 - 78,303,436 (+)NCBImm8
Celera178,786,483 - 78,890,682 (+)NCBICelera
Cytogenetic Map1C4NCBI
Sgpp2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2979,762,658 - 79,884,665 (+)NCBI
Rnor_6.0 Ensembl984,203,072 - 84,319,874 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0984,203,094 - 84,321,269 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0983,961,688 - 84,075,946 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4977,679,320 - 77,799,178 (+)NCBIRGSC3.4rn4RGSC3.4
Celera977,274,290 - 77,388,812 (+)NCBICelera
Cytogenetic Map9q33NCBI
Sgpp2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545311,242,647 - 11,359,569 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545311,244,077 - 11,361,990 (-)NCBIChiLan1.0ChiLan1.0
SGPP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12B228,300,677 - 228,385,137 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B228,300,673 - 228,381,565 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02B109,668,923 - 109,803,950 (+)NCBIMhudiblu_PPA_v0panPan3
SGPP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13728,536,815 - 28,639,380 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3729,372,695 - 29,474,494 (+)NCBI
ROS_Cfam_1.03728,560,624 - 28,662,588 (+)NCBI
UMICH_Zoey_3.13728,472,739 - 28,574,349 (+)NCBI
UNSW_CanFamBas_1.03728,404,302 - 28,505,973 (+)NCBI
UU_Cfam_GSD_1.03728,422,422 - 28,524,202 (+)NCBI
Sgpp2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303178,063,326 - 178,174,545 (+)NCBI
SpeTri2.0NW_0049365694,405,804 - 4,518,637 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SGPP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15124,318,271 - 124,462,851 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115124,316,309 - 124,462,855 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215137,863,888 - 137,960,378 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SGPP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.110108,339,433 - 108,480,411 (+)NCBI
Vero_WHO_p1.0NW_02366604090,897,357 - 91,035,535 (-)NCBI
Sgpp2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248232,635,128 - 2,756,566 (-)NCBI

Position Markers
D2S2300  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh372223,299,620 - 223,299,854UniSTSGRCh37
Build 362223,007,864 - 223,008,098RGDNCBI36
Celera2217,067,797 - 217,068,047RGD
Cytogenetic Map2q36.1UniSTS
HuRef2215,153,640 - 215,153,892UniSTS
Marshfield Genetic Map2222.2RGD
Marshfield Genetic Map2222.2UniSTS
Genethon Genetic Map2229.6UniSTS
deCODE Assembly Map2225.34UniSTS
Whitehead-YAC Contig Map2 UniSTS
SHGC-83242  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh372223,368,152 - 223,368,454UniSTSGRCh37
Build 362223,076,396 - 223,076,698RGDNCBI36
Celera2217,136,348 - 217,136,650RGD
Cytogenetic Map2q36.1UniSTS
HuRef2215,222,205 - 215,222,507UniSTS
RH122791  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh372223,382,799 - 223,383,086UniSTSGRCh37
Build 362223,091,043 - 223,091,330RGDNCBI36
Celera2217,150,991 - 217,151,278RGD
Cytogenetic Map2q36.1UniSTS
HuRef2215,236,823 - 215,237,110UniSTS
TNG Radiation Hybrid Map662621.0UniSTS
G63032  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh372223,353,945 - 223,354,224UniSTSGRCh37
Build 362223,062,189 - 223,062,468RGDNCBI36
Celera2217,122,140 - 217,122,419RGD
Cytogenetic Map2q36.1UniSTS
HuRef2215,207,995 - 215,208,274UniSTS
TNG Radiation Hybrid Map662638.0UniSTS
SHGC-146400  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh372223,312,032 - 223,312,364UniSTSGRCh37
Build 362223,020,276 - 223,020,608RGDNCBI36
Celera2217,080,230 - 217,080,562RGD
Cytogenetic Map2q36.1UniSTS
HuRef2215,166,075 - 215,166,407UniSTS
TNG Radiation Hybrid Map2123670.0UniSTS
SHGC-141517  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh372223,326,616 - 223,326,814UniSTSGRCh37
Build 362223,034,860 - 223,035,058RGDNCBI36
Celera2217,094,813 - 217,095,011RGD
Cytogenetic Map2q36.1UniSTS
HuRef2215,180,668 - 215,180,866UniSTS
TNG Radiation Hybrid Map2123628.0UniSTS
SHGC-153751  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh372223,291,353 - 223,291,689UniSTSGRCh37
Build 362222,999,597 - 222,999,933RGDNCBI36
Celera2217,059,630 - 217,059,966RGD
Cytogenetic Map2q36.1UniSTS
HuRef2215,145,377 - 215,145,713UniSTS
TNG Radiation Hybrid Map2123653.0UniSTS
D11S3114  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map9q34.13UniSTS
Cytogenetic Map15q13UniSTS
Cytogenetic Map3p22-p21.3UniSTS
Cytogenetic Map1q32.1UniSTS
Cytogenetic Map7p14.1UniSTS
Cytogenetic Map2q22.3UniSTS
Cytogenetic Map3p24.3UniSTS
Cytogenetic Map17q25.3UniSTS
Cytogenetic Map7q31.1UniSTS
Cytogenetic Map7q21.11UniSTS
Cytogenetic Map5q31UniSTS
Cytogenetic Map22q13.33UniSTS
Cytogenetic Map8q22.3UniSTS
Cytogenetic Map2p25.1UniSTS
Cytogenetic Map3q22-q24UniSTS
Cytogenetic Map5q23.3-q31.1UniSTS
Cytogenetic Map8p21.3UniSTS
Cytogenetic Map14q32.3UniSTS
Cytogenetic Map7q11.23UniSTS
Cytogenetic Map7q32UniSTS
Cytogenetic Map17q11UniSTS
Cytogenetic Map1q21-q23UniSTS
Cytogenetic Map12q13.13UniSTS
Cytogenetic Map17p12-p11.2UniSTS
Cytogenetic Map6p21.1UniSTS
Cytogenetic MapXp22.2UniSTS
Cytogenetic Map19p13.11UniSTS
Cytogenetic Map19p13.2UniSTS
Cytogenetic Map16q24.3UniSTS
Cytogenetic Map9q34.3UniSTS
Cytogenetic Map19q13.33UniSTS
Cytogenetic Map2q32.3UniSTS
Cytogenetic Map1q25.1UniSTS
Cytogenetic Map10p15.3UniSTS
Cytogenetic Map12q12UniSTS
Cytogenetic Map12q24.31UniSTS
Cytogenetic Map15q15UniSTS
Cytogenetic Map22q11.23UniSTS
Cytogenetic Map17q25UniSTS
Cytogenetic Map16q22.1UniSTS
Cytogenetic Map19p13.3UniSTS
Cytogenetic Map5q23.3UniSTS
Cytogenetic Map15q15.1UniSTS
Cytogenetic Map3q27.2UniSTS
Cytogenetic Map20q13.12UniSTS
Cytogenetic MapXp11.23UniSTS
Cytogenetic Map16q13UniSTS
Cytogenetic Map19q13.3UniSTS
Cytogenetic Map1q32UniSTS
Cytogenetic Map6q25.3UniSTS
Cytogenetic Map1p36.2UniSTS
Cytogenetic Map15q11.2-q21.3UniSTS
Cytogenetic Map14q24.3UniSTS
Cytogenetic Map19p13UniSTS
Cytogenetic Map1p35.1UniSTS
Cytogenetic Map17q11.2UniSTS
Cytogenetic Map12q13.2UniSTS
Cytogenetic Map22q13.1UniSTS
Cytogenetic Map11p15UniSTS
Cytogenetic Map8q24.13UniSTS
Cytogenetic Map1q41UniSTS
Cytogenetic Map19q13.12UniSTS
Cytogenetic Map17q12UniSTS
Cytogenetic Map12p12.1UniSTS
Cytogenetic Map15q25.2UniSTS
Cytogenetic Map2p13.1UniSTS
Cytogenetic Map1p36.13UniSTS
Cytogenetic Map2q12.1UniSTS
Cytogenetic Map11q23.3UniSTS
Cytogenetic MapXp11.3UniSTS
Cytogenetic Map17p13UniSTS
Cytogenetic Map20q13.13UniSTS
Cytogenetic Map4q12UniSTS
Cytogenetic Map16q24UniSTS
Cytogenetic Map17p13.1UniSTS
Cytogenetic Map10q23.1UniSTS
Cytogenetic Map1q44UniSTS
Cytogenetic Map3p21.31UniSTS
Cytogenetic Map17p13.2UniSTS
Cytogenetic Map9q33.3UniSTS
Cytogenetic Map2p11.2UniSTS
Cytogenetic Map22q12.1UniSTS
Cytogenetic Map17q22.2UniSTS
Cytogenetic Map1p36.33UniSTS
Cytogenetic Map10q11.1UniSTS
Cytogenetic Map19q12UniSTS
Cytogenetic Map11q14.2UniSTS
Cytogenetic Map1q23.1UniSTS
Cytogenetic Map11p15.4UniSTS
Cytogenetic Map18q12.1-q21.1UniSTS
Cytogenetic Map2q37UniSTS
Cytogenetic Map20q11.21UniSTS
Cytogenetic Map6p21.32UniSTS
Cytogenetic Map10q26.3UniSTS
Cytogenetic Map7q22.1UniSTS
Cytogenetic Map14q12UniSTS
Cytogenetic Map8p11.22UniSTS
Cytogenetic Map19q13.32UniSTS
Cytogenetic Map17q21.31UniSTS
Cytogenetic Map17q21UniSTS
Cytogenetic Map2q21.3UniSTS
Cytogenetic Map2q21.1UniSTS
Cytogenetic Map6q27UniSTS
Cytogenetic Map2q33.1UniSTS
Cytogenetic Map9q21.12UniSTS
Cytogenetic Map7p22.2UniSTS
Cytogenetic Map20p13UniSTS
Cytogenetic Map17q25.1UniSTS
Cytogenetic Map10q24.31UniSTS
Cytogenetic Map15q22.31UniSTS
Cytogenetic Map11q12.3UniSTS
Cytogenetic Map2q31.1UniSTS
Cytogenetic Map1p36.21UniSTS
Cytogenetic Map1p31.1UniSTS
Cytogenetic Map1p36.11UniSTS
Cytogenetic Map1p32.3UniSTS
Cytogenetic Map3q13.31UniSTS
Cytogenetic Map6q13UniSTS
Cytogenetic Map1q21UniSTS
Cytogenetic Map3q21.3UniSTS
Cytogenetic Map19q13.4UniSTS
Cytogenetic Map12q23.2UniSTS
Cytogenetic Map1q21.3UniSTS
Cytogenetic Map1q22UniSTS
Cytogenetic Map1p36UniSTS
Cytogenetic Map4p14UniSTS
Cytogenetic Map19p12UniSTS
Cytogenetic Map22q11.21UniSTS
Cytogenetic Map7q22UniSTS
Cytogenetic Map16q22UniSTS
Cytogenetic Map2q11.2UniSTS
Cytogenetic Map19p13.1-p12UniSTS
Cytogenetic Map16p13.3UniSTS
Cytogenetic Map2p22.1UniSTS
Cytogenetic Map1p34.3UniSTS
Cytogenetic Map5q23.1UniSTS
Cytogenetic Map8q24.3UniSTS
Cytogenetic Map1q25UniSTS
Cytogenetic Map1q21.2UniSTS
Cytogenetic Map12q22UniSTS
Cytogenetic Map21q22.3UniSTS
Cytogenetic Map21q22.11UniSTS
Cytogenetic Map3q23UniSTS
Cytogenetic Map6p21.3UniSTS
Cytogenetic Map2q12.3UniSTS
Cytogenetic Map12p13.31UniSTS
Cytogenetic Map8p11.2UniSTS
Cytogenetic Map7q21.1UniSTS
Cytogenetic Map19q13.43UniSTS
Cytogenetic Map2q35UniSTS
Cytogenetic Map5q35.3UniSTS
Cytogenetic Map5p13UniSTS
Cytogenetic Map22q11.2UniSTS
Cytogenetic Map5p12UniSTS
Cytogenetic Map1p34.2UniSTS
Cytogenetic Map12q21.1UniSTS
Cytogenetic Map16q12.1UniSTS
Cytogenetic Map2q37.1UniSTS
Cytogenetic Map7p14.3UniSTS
Cytogenetic MapXq13.2UniSTS
Cytogenetic Map18p11.21UniSTS
Cytogenetic Map17p13.3UniSTS
Cytogenetic Map14q24UniSTS
Cytogenetic Map15q24.1UniSTS
Cytogenetic Map7p22.3UniSTS
Cytogenetic Map22q13.2UniSTS
Cytogenetic Map2p21UniSTS
Cytogenetic Map22q11.1UniSTS
Cytogenetic Map22q13UniSTS
Cytogenetic Map11q13.1-q13.2UniSTS
Cytogenetic Map7p22UniSTS
Cytogenetic Map1p32-p31UniSTS
Cytogenetic Map19q13.1UniSTS
Cytogenetic Map11q13UniSTS
Cytogenetic Map7q21-q22UniSTS
Cytogenetic Map11p15.5UniSTS
Cytogenetic Map12p13.1UniSTS
Cytogenetic Map8p22UniSTS
Cytogenetic Map3q25.33UniSTS
Cytogenetic Map10q23.31UniSTS
Cytogenetic Map1p13.3UniSTS
Cytogenetic Map20q13.3UniSTS
Cytogenetic Map17q23.2UniSTS
Cytogenetic Map14q24.1UniSTS
Cytogenetic Map1p36.32UniSTS
Cytogenetic Map10q24.32UniSTS
Cytogenetic Map2q33.2UniSTS
Cytogenetic Map1p35-p34.3UniSTS
Cytogenetic Map7p11.2UniSTS
Cytogenetic Map5q35.2UniSTS
Cytogenetic Map10q22.3UniSTS
Cytogenetic Map2p13.3UniSTS
Cytogenetic Map3q12.3UniSTS
Cytogenetic Map12qUniSTS
Cytogenetic Map12p12.2-p11.2UniSTS
Cytogenetic Map2p23.3UniSTS
Cytogenetic Map2q14.3UniSTS
Cytogenetic Map7p13UniSTS
Cytogenetic Map11p15.3UniSTS
Cytogenetic Map1p36.11-p34.2UniSTS
Cytogenetic Map4q35.1UniSTS
Cytogenetic Map6q22.31UniSTS
Cytogenetic Map11q13.1UniSTS
Cytogenetic Map16q22.2UniSTS
Cytogenetic Map11q22.3UniSTS
Cytogenetic Map10p14UniSTS
Cytogenetic Map8q22.1UniSTS
Cytogenetic Map6q21UniSTS
Cytogenetic Map4p16.1UniSTS
Cytogenetic Map20p11.23UniSTS
Cytogenetic Map3q22.3UniSTS
Cytogenetic Map3q27.3UniSTS
Cytogenetic Map22q12.2UniSTS
Cytogenetic Map14q32.11UniSTS
Cytogenetic Map15q14UniSTS
Cytogenetic Map5q31.3UniSTS
Cytogenetic Map11q14UniSTS
Cytogenetic Map15q21UniSTS
Cytogenetic Map3q27.1UniSTS
Cytogenetic Map3p14.3UniSTS
Cytogenetic Map12p13.2UniSTS
Cytogenetic Map6p21.2UniSTS
Cytogenetic Map10q11.1-q24UniSTS
Cytogenetic Map1p36.31UniSTS
Cytogenetic Map1p31.3UniSTS
Cytogenetic MapXp11.22UniSTS
Cytogenetic Map10p15.1UniSTS
Cytogenetic MapXq24UniSTS
Cytogenetic Map7p22.1UniSTS
Cytogenetic Map14q31.1UniSTS
Cytogenetic Map19q13.2UniSTS
Cytogenetic MapXq21.1UniSTS
Cytogenetic Map15q22UniSTS
Cytogenetic Map6p25UniSTS
Cytogenetic Map16p11.2UniSTS
Cytogenetic MapXq12-q13UniSTS
Cytogenetic Map12q13.3UniSTS
Cytogenetic Map9q34.11UniSTS
Cytogenetic Map7q31UniSTS
Cytogenetic Map7q31.1-q31.3UniSTS
Cytogenetic Map11q13.4UniSTS
Cytogenetic Map7q34UniSTS
Cytogenetic MapXq13.1-q21.1UniSTS
Cytogenetic Map20pter-q12UniSTS
Cytogenetic Map14q32.31UniSTS
Cytogenetic Map12q13.11-q14.3UniSTS
Cytogenetic Map2q32.1UniSTS
Cytogenetic Map15q21-q22UniSTS
Cytogenetic Map19q13UniSTS
Cytogenetic Map20q11.22-q11.23UniSTS
Cytogenetic Map10q23UniSTS
Cytogenetic Map17p11.2UniSTS
Cytogenetic Map11p11.2UniSTS
Cytogenetic Map4q21.22UniSTS
Cytogenetic Map13q14.2UniSTS
Cytogenetic Map1q21.2-q21.3UniSTS
Cytogenetic Map9p24.1UniSTS
Cytogenetic Map15q15.3UniSTS
Cytogenetic Map3q13.33UniSTS
Cytogenetic Map8q11.2UniSTS
Cytogenetic MapXq12UniSTS
Cytogenetic Map1q41-q42.2UniSTS
Cytogenetic Map11q22-q23UniSTS
Cytogenetic Map12q23-q24.1UniSTS
Cytogenetic Map1p36.3UniSTS
Cytogenetic Map1p33UniSTS
Cytogenetic Map6p12.3UniSTS
Cytogenetic Map1q43UniSTS
Cytogenetic Map15q26.3UniSTS
Cytogenetic Map15q13.1UniSTS
Cytogenetic MapXq13.1UniSTS
Cytogenetic Map10q11.21UniSTS
Cytogenetic Map17q23.3UniSTS
Cytogenetic Map3p21UniSTS
Cytogenetic Map15q11-q13UniSTS
Cytogenetic Map13q12-q14UniSTS
Cytogenetic Map18q21.1UniSTS
Cytogenetic Map9p23UniSTS
Cytogenetic Map7p12.3UniSTS
Cytogenetic Map3p25.3UniSTS
Cytogenetic Map2q37.2UniSTS
Cytogenetic Map2p14UniSTS
Cytogenetic Map10q11.22UniSTS
Cytogenetic Map1p21.2UniSTS
Cytogenetic Map3p22.1UniSTS
Cytogenetic Map19q13.42UniSTS
Cytogenetic Map19q13.31UniSTS
Cytogenetic Map14q32.2UniSTS
Cytogenetic Map17q21.2UniSTS
Cytogenetic Map13q32.2UniSTS
Cytogenetic Map14q23.1UniSTS
Cytogenetic Map5q11.2UniSTS
Cytogenetic Map2q24.1UniSTS
Cytogenetic Map7q32.1UniSTS
Cytogenetic Map19p13.1UniSTS
Cytogenetic Map5q31.1UniSTS
Cytogenetic Map8p12-p11UniSTS
Cytogenetic Map1q31-q32UniSTS
Cytogenetic Map6q24.1UniSTS
Cytogenetic Map10q24UniSTS
Cytogenetic MapXq28UniSTS
Cytogenetic Map15q26.1UniSTS
Cytogenetic Map10q26.11UniSTS
Cytogenetic Map8p21.1UniSTS
Cytogenetic Map7p15.3UniSTS
Cytogenetic Map7p21.1UniSTS
Cytogenetic Map4q21.1UniSTS
Cytogenetic Map15q11.2UniSTS
Cytogenetic Map13q32.3UniSTS
Cytogenetic MapXq25UniSTS
Cytogenetic Map12q24.33UniSTS
Cytogenetic Map14q23.2UniSTS
Cytogenetic Map2q24.2UniSTS
Cytogenetic Map16p12.2UniSTS
Cytogenetic Map15q21.2UniSTS
Cytogenetic Map3p26.1-p25.1UniSTS
Cytogenetic Map3q13.2UniSTS
Cytogenetic Map4p15.2UniSTS
Cytogenetic Map17q24-q25UniSTS
Cytogenetic Map5q12.1UniSTS
Cytogenetic Map5q15UniSTS
Cytogenetic Map17q22UniSTS
Cytogenetic Map17q21.1UniSTS
Cytogenetic Map8q23.1UniSTS
Cytogenetic Map10p12.31UniSTS
Cytogenetic Map2q33.3UniSTS
Cytogenetic MapXq21UniSTS
Cytogenetic Map6p12UniSTS
Cytogenetic Map2p15-p13UniSTS
Cytogenetic Map19qUniSTS
Cytogenetic Map20p11UniSTS
Cytogenetic Map22q12.3-q13.1UniSTS
Cytogenetic Map1q25.2UniSTS
Cytogenetic Map10q21.3UniSTS
Cytogenetic Map3p21.1-p14.3UniSTS
Cytogenetic Map6p12.1UniSTS
Cytogenetic Map14q23.3UniSTS
Cytogenetic Map4p16.3UniSTS
Cytogenetic Map6q16.1UniSTS
Cytogenetic Map5p13.1UniSTS
Cytogenetic Map9q21.11UniSTS
Cytogenetic Map8q12UniSTS
Cytogenetic Map1q24.2UniSTS
Cytogenetic Map2q34UniSTS
Cytogenetic Map8p11.23UniSTS
Cytogenetic Map14q21.2UniSTS
Cytogenetic Map7q35UniSTS
Cytogenetic Map5p13.3UniSTS
Cytogenetic Map1q42.3UniSTS
Cytogenetic Map1q22-q23UniSTS
Cytogenetic Map6p21.31UniSTS
Cytogenetic Map4q21UniSTS
Cytogenetic Map10p13UniSTS
Cytogenetic Map5q13UniSTS
Cytogenetic Map4q13.3UniSTS
Cytogenetic Map9q34.1UniSTS
Cytogenetic Map5q13.2UniSTS
Cytogenetic Map17p12UniSTS
Cytogenetic Map9q22.1-q22.2UniSTS
Cytogenetic Map18q12.1UniSTS
Cytogenetic Map13q14.11UniSTS
Cytogenetic Map7q21.2UniSTS
Cytogenetic Map9p22.3UniSTS
Cytogenetic Map8q21.11UniSTS
Cytogenetic Map6p22.3UniSTS
Cytogenetic Map5q32UniSTS
Cytogenetic Map4p12UniSTS
Cytogenetic Map2q13UniSTS
Cytogenetic Map21q11.2UniSTS
Cytogenetic Map1p34.1UniSTS
Cytogenetic Map19q11UniSTS
Cytogenetic Map8p21.2UniSTS
Cytogenetic Map15q26.2UniSTS
Cytogenetic Map14q22.1UniSTS
Cytogenetic Map11p15.1UniSTS
Cytogenetic Map10q25.3UniSTS
Cytogenetic Map20q11.23UniSTS
Cytogenetic Map12q13.11UniSTS
Cytogenetic Map11q13.2UniSTS
Cytogenetic Map5p13.2UniSTS
Cytogenetic Map16q24.1UniSTS
Cytogenetic Map9q32UniSTS
Cytogenetic Map2q36.1UniSTS
Cytogenetic Map1q42.13UniSTS
Cytogenetic Map1q21.1UniSTS
Cytogenetic Map17q21.32UniSTS
Cytogenetic Map16q23.1UniSTS
Cytogenetic Map3q25.1UniSTS
Cytogenetic Map1p22.2UniSTS
Cytogenetic Map1p32.2-p32.1UniSTS
Cytogenetic Map15q24UniSTS
Cytogenetic MapXp21.1UniSTS
Cytogenetic Map12q14.3UniSTS
Cytogenetic Map7q36UniSTS
Cytogenetic Map9q34UniSTS
Cytogenetic Map11q22UniSTS
Cytogenetic Map5p15.3UniSTS
Cytogenetic Map7q11.21UniSTS
Cytogenetic Map20q13.3-qterUniSTS
Cytogenetic Map13q13.1UniSTS
Cytogenetic Map1p33-p32UniSTS
Cytogenetic Map21q22.2UniSTS
Cytogenetic Map3q13.13-q13.2UniSTS
Cytogenetic Map3p21.3UniSTS
Cytogenetic Map12p11.21UniSTS
Cytogenetic Map7qUniSTS
Cytogenetic Map11q13.5UniSTS
Cytogenetic Map4q32UniSTS
Cytogenetic Map9q22.33UniSTS
Cytogenetic Map5q35.1UniSTS
Cytogenetic Map9p13.3UniSTS
Cytogenetic Map13q14.13UniSTS
Cytogenetic Map10p12.1UniSTS
Cytogenetic Map20q13.33UniSTS
Cytogenetic Map19p13.13UniSTS
Cytogenetic Map4q13.2UniSTS
Cytogenetic Map4q31.23UniSTS
Cytogenetic Map7q36.3UniSTS
Cytogenetic Map14q24.2UniSTS

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:861
Count of miRNA genes:610
Interacting mature miRNAs:685
Transcripts:ENST00000321276
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system adipose tissue appendage entire extraembryonic component
High
Medium 614 48 877 92 641 28 1276 44 823 244 303 935 69 67 682
Low 1424 1444 545 239 817 145 1471 1318 2552 158 957 620 102 736 977 1
Below cutoff 389 1466 296 284 480 285 1581 818 348 14 192 49 2 399 1109 3

Sequence


Reference Sequences
RefSeq Acc Id: ENST00000321276   ⟹   ENSP00000315137
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl2222,424,543 - 222,562,621 (+)Ensembl
RefSeq Acc Id: NM_001320833   ⟹   NP_001307762
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382222,424,543 - 222,562,621 (+)NCBI
CHM1_12223,295,637 - 223,433,843 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001320834   ⟹   NP_001307763
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382222,423,988 - 222,562,621 (+)NCBI
CHM1_12223,295,182 - 223,433,843 (+)NCBI
Sequence:
RefSeq Acc Id: NM_152386   ⟹   NP_689599
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382222,424,543 - 222,562,621 (+)NCBI
GRCh372223,288,771 - 223,427,342 (+)NCBI
Build 362222,997,566 - 223,131,861 (+)NCBI Archive
Celera2217,107,484 - 217,191,808 (+)RGD
HuRef2215,143,345 - 215,277,358 (+)ENTREZGENE
CHM1_12223,295,637 - 223,433,843 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017003355   ⟹   XP_016858844
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382222,447,209 - 222,562,621 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_689599   ⟸   NM_152386
- Peptide Label: isoform a
- UniProtKB: Q8IWX5 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001307763   ⟸   NM_001320834
- Peptide Label: isoform b
- UniProtKB: Q8IWX5 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001307762   ⟸   NM_001320833
- Peptide Label: isoform b
- UniProtKB: Q8IWX5 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_016858844   ⟸   XM_017003355
- Peptide Label: isoform X1
- UniProtKB: Q8IWX5 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSP00000315137   ⟸   ENST00000321276
Protein Domains
acidPPc

Promoters
RGD ID:6862946
Promoter ID:EPDNEW_H4638
Type:initiation region
Name:SGPP2_2
Description:sphingosine-1-phosphate phosphatase 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H4639  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh382222,423,988 - 222,424,048EPDNEW
RGD ID:6862948
Promoter ID:EPDNEW_H4639
Type:initiation region
Name:SGPP2_1
Description:sphingosine-1-phosphate phosphatase 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H4638  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh382222,424,543 - 222,424,603EPDNEW
RGD ID:6798158
Promoter ID:HG_KWN:37448
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   K562,   Lymphoblastoid
Transcripts:ENST00000392068,   OTTHUMT00000256856,   UC010FWR.1
Position:
Human AssemblyChrPosition (strand)Source
Build 362222,996,806 - 222,997,462 (+)MPROMDB

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 2q32.3-37.3(chr2:194898783-236473913)x3 copy number gain See cases [RCV000051119] Chr2:194898783..236473913 [GRCh38]
Chr2:195763507..237382556 [GRCh37]
Chr2:195471752..237047295 [NCBI36]
Chr2:2q32.3-37.3
pathogenic
GRCh38/hg38 2q35-36.3(chr2:219081620-225430308)x1 copy number loss See cases [RCV000052634] Chr2:219081620..225430308 [GRCh38]
Chr2:219946342..226295024 [GRCh37]
Chr2:219654586..226003268 [NCBI36]
Chr2:2q35-36.3
pathogenic
GRCh38/hg38 2q36.1-36.2(chr2:221387419-224669350)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052635]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052635]|See cases [RCV000052635] Chr2:221387419..224669350 [GRCh38]
Chr2:222252139..225534067 [GRCh37]
Chr2:221960383..225242311 [NCBI36]
Chr2:2q36.1-36.2
pathogenic
GRCh38/hg38 2q32.2-37.3(chr2:188818195-242065208)x3 copy number gain See cases [RCV000052958] Chr2:188818195..242065208 [GRCh38]
Chr2:189682921..243007359 [GRCh37]
Chr2:189391166..242656032 [NCBI36]
Chr2:2q32.2-37.3
pathogenic
GRCh38/hg38 2q32.2-37.3(chr2:190310736-241892770)x3 copy number gain See cases [RCV000052959] Chr2:190310736..241892770 [GRCh38]
Chr2:191175462..242834921 [GRCh37]
Chr2:190883707..242483594 [NCBI36]
Chr2:2q32.2-37.3
pathogenic
GRCh38/hg38 2q32.3-37.3(chr2:193122313-241074980)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052960]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052960]|See cases [RCV000052960] Chr2:193122313..241074980 [GRCh38]
Chr2:193987039..242014395 [GRCh37]
Chr2:193695284..241663068 [NCBI36]
Chr2:2q32.3-37.3
pathogenic
GRCh38/hg38 2q34-36.3(chr2:212614422-227121230)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052964]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052964]|See cases [RCV000052964] Chr2:212614422..227121230 [GRCh38]
Chr2:213479146..227985946 [GRCh37]
Chr2:213187391..227694190 [NCBI36]
Chr2:2q34-36.3
pathogenic
GRCh38/hg38 2q35-36.3(chr2:219547204-228287942)x4 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052965]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052965]|See cases [RCV000052965] Chr2:219547204..228287942 [GRCh38]
Chr2:220411926..229152658 [GRCh37]
Chr2:220120170..228860902 [NCBI36]
Chr2:2q35-36.3
pathogenic
NM_152386.2(SGPP2):c.669G>A (p.Leu223=) single nucleotide variant Malignant melanoma [RCV000060501] Chr2:222558367 [GRCh38]
Chr2:223423086 [GRCh37]
Chr2:223131330 [NCBI36]
Chr2:2q36.1
not provided
GRCh38/hg38 2q36.1-36.2(chr2:221663502-224426183)x1 copy number loss See cases [RCV000135355] Chr2:221663502..224426183 [GRCh38]
Chr2:222528222..225290900 [GRCh37]
Chr2:222236466..224999144 [NCBI36]
Chr2:2q36.1-36.2
pathogenic
GRCh38/hg38 2q34-37.3(chr2:210579676-242126245)x3 copy number gain See cases [RCV000135934] Chr2:210579676..242126245 [GRCh38]
Chr2:211444400..243059659 [GRCh37]
Chr2:211152645..242717069 [NCBI36]
Chr2:2q34-37.3
pathogenic
GRCh38/hg38 2q31.3-36.2(chr2:180513793-224302848)x3 copy number gain See cases [RCV000139446] Chr2:180513793..224302848 [GRCh38]
Chr2:181378520..225167565 [GRCh37]
Chr2:181086765..224875809 [NCBI36]
Chr2:2q31.3-36.2
pathogenic
GRCh38/hg38 2q32.2-37.3(chr2:189436149-241841232)x3 copy number gain See cases [RCV000142307] Chr2:189436149..241841232 [GRCh38]
Chr2:190300875..242783384 [GRCh37]
Chr2:190009120..242432057 [NCBI36]
Chr2:2q32.2-37.3
pathogenic
GRCh38/hg38 2q35-37.3(chr2:218101759-242126245)x3 copy number gain See cases [RCV000143216] Chr2:218101759..242126245 [GRCh38]
Chr2:218966482..243059659 [GRCh37]
Chr2:218674727..242717069 [NCBI36]
Chr2:2q35-37.3
pathogenic
GRCh37/hg19 2q35-37.3(chr2:219966808-237815985)x3 copy number gain See cases [RCV000448049] Chr2:219966808..237815985 [GRCh37]
Chr2:2q35-37.3
pathogenic
GRCh37/hg19 2q36.1-37.1(chr2:223378640-232061074)x1 copy number loss See cases [RCV000448773] Chr2:223378640..232061074 [GRCh37]
Chr2:2q36.1-37.1
likely pathogenic
GRCh37/hg19 2p25.3-q37.3(chr2:12771-242783384) copy number gain See cases [RCV000512056] Chr2:12771..242783384 [GRCh37]
Chr2:2p25.3-q37.3
pathogenic
GRCh37/hg19 2q34-37.3(chr2:213518431-242783384)x3 copy number gain See cases [RCV000512009] Chr2:213518431..242783384 [GRCh37]
Chr2:2q34-37.3
pathogenic
GRCh37/hg19 2q36.1-37.3(chr2:222077224-239394441)x3 copy number gain See cases [RCV000511816] Chr2:222077224..239394441 [GRCh37]
Chr2:2q36.1-37.3
pathogenic
GRCh37/hg19 2p25.3-q37.3(chr2:12771-242783384)x3 copy number gain See cases [RCV000511212] Chr2:12771..242783384 [GRCh37]
Chr2:2p25.3-q37.3
pathogenic
GRCh37/hg19 2q35-36.3(chr2:217374144-227643620)x1 copy number loss not provided [RCV000585275] Chr2:217374144..227643620 [GRCh37]
Chr2:2q35-36.3
likely pathogenic
GRCh37/hg19 2q35-36.3(chr2:221439250-226170404)x1 copy number loss not provided [RCV000682155] Chr2:221439250..226170404 [GRCh37]
Chr2:2q35-36.3
pathogenic
GRCh37/hg19 2q35-36.2(chr2:220614743-225587770)x1 copy number loss not provided [RCV000682158] Chr2:220614743..225587770 [GRCh37]
Chr2:2q35-36.2
pathogenic
GRCh37/hg19 2q35-37.3(chr2:219225872-242016876)x3 copy number gain not provided [RCV000682170] Chr2:219225872..242016876 [GRCh37]
Chr2:2q35-37.3
pathogenic
GRCh37/hg19 2q35-36.3(chr2:218813434-227450699)x1 copy number loss not provided [RCV000682163] Chr2:218813434..227450699 [GRCh37]
Chr2:2q35-36.3
pathogenic
GRCh37/hg19 2p25.3-q37.3(chr2:15672-243101834)x3 copy number gain not provided [RCV000752804] Chr2:15672..243101834 [GRCh37]
Chr2:2p25.3-q37.3
pathogenic
GRCh37/hg19 2p25.3-q37.3(chr2:14238-243048760)x3 copy number gain not provided [RCV000752802] Chr2:14238..243048760 [GRCh37]
Chr2:2p25.3-q37.3
pathogenic
GRCh37/hg19 2q35-36.1(chr2:220608798-224217756)x1 copy number loss not provided [RCV000740901] Chr2:220608798..224217756 [GRCh37]
Chr2:2q35-36.1
pathogenic
Single allele duplication Neurodevelopmental disorder [RCV000787403] Chr2:188926928..225298653 [GRCh37]
Chr2:2q32.1-36.2
pathogenic
GRCh37/hg19 2q34-37.3(chr2:210779657-239879183)x3 copy number gain See cases [RCV000790568] Chr2:210779657..239879183 [GRCh37]
Chr2:2q34-37.3
pathogenic
GRCh37/hg19 2q36.1(chr2:223277982-223757490)x3 copy number gain not provided [RCV001259186] Chr2:223277982..223757490 [GRCh37]
Chr2:2q36.1
uncertain significance
GRCh37/hg19 2q31.2-37.3(chr2:178397959-243007457)x3 copy number gain See cases [RCV001263052] Chr2:178397959..243007457 [GRCh37]
Chr2:2q31.2-37.3
pathogenic
GRCh37/hg19 2q36.1(chr2:222621434-224754689)x1 copy number loss not provided [RCV001259185] Chr2:222621434..224754689 [GRCh37]
Chr2:2q36.1
pathogenic

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:19953 AgrOrtholog
COSMIC SGPP2 COSMIC
Ensembl Genes ENSG00000163082 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSP00000315137 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000321276 ENTREZGENE, UniProtKB/Swiss-Prot
GTEx ENSG00000163082 GTEx
HGNC ID HGNC:19953 ENTREZGENE
Human Proteome Map SGPP2 Human Proteome Map
InterPro P_Acid_Pase_2/haloperoxi_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  P_Acid_Pase_2/haloperoxidase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:130367 UniProtKB/Swiss-Prot
NCBI Gene 130367 ENTREZGENE
OMIM 612827 OMIM
Pfam PAP2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA134956234 PharmGKB
SMART acidPPc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48317 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt Q3B870_HUMAN UniProtKB/TrEMBL
  Q4ZFX2_HUMAN UniProtKB/TrEMBL
  Q53QF5_HUMAN UniProtKB/TrEMBL
  Q8IWX5 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary A3KPB4 UniProtKB/Swiss-Prot
  Q8N8Q6 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-07-27 SGPP2  sphingosine-1-phosphate phosphatase 2  SGPP2  sphingosine-1-phosphate phosphotase 2  Symbol and/or name change 5135510 APPROVED