CXCL13 (C-X-C motif chemokine ligand 13) - Rat Genome Database

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Gene: CXCL13 (C-X-C motif chemokine ligand 13) Homo sapiens
Analyze
Symbol: CXCL13
Name: C-X-C motif chemokine ligand 13
RGD ID: 1342514
HGNC Page HGNC
Description: Exhibits chemokine receptor binding activity; fibroblast growth factor binding activity; and heparin binding activity. Involved in several processes, including antimicrobial humoral immune response mediated by antimicrobial peptide; cell chemotaxis; and regulation of chemotaxis. Localizes to extracellular region.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ANGIE; ANGIE2; b cell-attracting chemokine 1; b lymphocyte chemoattractant; B-cell chemoattractant; B-cell-attracting chemokine 1; B-cell-homing chemokine (ligand for Burkitt's lymphoma receptor-1); B-lymphocyte chemoattractant; BCA-1; BCA1; BLC; BLR1L; C-X-C motif chemokine 13; chemokine (C-X-C motif) ligand 13 (B-cell chemoattractant); CXC chemokine BLC; SCYB13; small inducible cytokine B subfamily (Cys-X-Cys motif), member 13 (B-cell chemoattractant); small-inducible cytokine B13
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl477,511,753 - 77,611,834 (+)EnsemblGRCh38hg38GRCh38
GRCh38477,511,753 - 77,611,834 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37478,432,907 - 78,532,988 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36478,651,931 - 78,752,010 (+)NCBINCBI36hg18NCBI36
Build 34478,790,084 - 78,890,165NCBI
Celera475,734,287 - 75,834,362 (+)NCBI
Cytogenetic Map4q21.1NCBI
HuRef474,184,783 - 74,284,964 (+)NCBIHuRef
CHM1_1478,409,854 - 78,509,941 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (ISO)
1-nitropyrene  (EXP)
17beta-estradiol  (ISO)
17beta-estradiol 3-benzoate  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-trinitrobenzenesulfonic acid  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3-chloropropane-1,2-diol  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
7,12-dimethyltetraphene  (ISO)
acrylamide  (ISO)
aflatoxin B1  (EXP,ISO)
andrographolide  (ISO)
antirheumatic drug  (EXP)
asperentin  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[b]fluoranthene  (ISO)
Benzo[k]fluoranthene  (ISO)
beta-naphthoflavone  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (ISO)
bleomycin A2  (ISO)
bromobenzene  (ISO)
cadmium dichloride  (ISO)
carbamazepine  (EXP)
carbon nanotube  (EXP,ISO)
cefaloridine  (ISO)
choline  (ISO)
chrysene  (ISO)
ciguatoxin CTX1B  (ISO)
cyclosporin A  (EXP,ISO)
decabromodiphenyl ether  (ISO)
dextran sulfate  (ISO)
dibutyl phthalate  (ISO)
diclofenac  (ISO)
doxorubicin  (ISO)
furan  (ISO)
genistein  (ISO)
graphene oxide  (ISO)
iron(2+) sulfate (anhydrous)  (EXP)
isoprenaline  (ISO)
lipopolysaccharide  (ISO)
metformin  (ISO)
methylmercury chloride  (EXP,ISO)
mifepristone  (EXP)
mycotoxin  (ISO)
N,N-diethyl-m-toluamide  (EXP)
N-nitrosodimethylamine  (ISO)
neoechinulin A  (ISO)
nickel dichloride  (EXP)
O-methyleugenol  (EXP)
paracetamol  (EXP)
phenobarbital  (ISO)
pirinixic acid  (ISO)
rotenone  (ISO)
silicon dioxide  (EXP,ISO)
sirolimus  (ISO)
sodium arsenite  (EXP,ISO)
sodium dichromate  (ISO)
sterigmatocystin  (ISO)
succimer  (EXP,ISO)
sunitinib  (ISO)
taurocholic acid  (ISO)
testosterone  (ISO)
tetrachloromethane  (ISO)
tetraphene  (ISO)
titanium dioxide  (ISO)
tofacitinib  (EXP)
toluene 2,4-diisocyanate  (ISO)
trimellitic anhydride  (ISO)
vinclozolin  (ISO)
zinc dichloride  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
1. GOA_HUMAN data from the GO Consortium
2. RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:9463416   PMID:9486651   PMID:10706668   PMID:11554781   PMID:11708770   PMID:11877260   PMID:12393412   PMID:12406091   PMID:12477932   PMID:12732660   PMID:12949249   PMID:14763921  
PMID:15284119   PMID:15489334   PMID:15546958   PMID:15780119   PMID:15929033   PMID:15934082   PMID:15965952   PMID:16169070   PMID:16318584   PMID:16531331   PMID:16543475   PMID:16678487  
PMID:17082584   PMID:17082648   PMID:17207965   PMID:17474076   PMID:17495955   PMID:17562761   PMID:17592274   PMID:17652619   PMID:17703412   PMID:17709502   PMID:17949547   PMID:18172003  
PMID:18292286   PMID:18354239   PMID:18528326   PMID:18550853   PMID:18566383   PMID:18577758   PMID:18668547   PMID:18757429   PMID:18773213   PMID:18780835   PMID:18781150   PMID:18792075  
PMID:19031272   PMID:19095563   PMID:19258923   PMID:19375853   PMID:19575892   PMID:19671684   PMID:19773382   PMID:19774453   PMID:19805441   PMID:19807029   PMID:19816883   PMID:19955043  
PMID:19965843   PMID:19996075   PMID:20011704   PMID:20042073   PMID:20056178   PMID:20109310   PMID:20223524   PMID:20237496   PMID:20400187   PMID:20412587   PMID:20495539   PMID:20503287  
PMID:21078761   PMID:21084753   PMID:21135023   PMID:21191639   PMID:21211990   PMID:21305530   PMID:21320077   PMID:21372118   PMID:21576203   PMID:21642390   PMID:21645150   PMID:21873635  
PMID:22000402   PMID:22008312   PMID:22036953   PMID:22044682   PMID:22330139   PMID:22335599   PMID:22591862   PMID:22607768   PMID:22718279   PMID:22840692   PMID:22913878   PMID:22975753  
PMID:23109547   PMID:23175382   PMID:23189125   PMID:23247143   PMID:23250934   PMID:23322500   PMID:23383108   PMID:23570798   PMID:23904442   PMID:23925290   PMID:24027428   PMID:24138885  
PMID:24337540   PMID:24393484   PMID:24628285   PMID:24732574   PMID:24764267   PMID:24766912   PMID:24907903   PMID:25010623   PMID:25031316   PMID:25077417   PMID:25217476   PMID:25249397  
PMID:25267627   PMID:25271023   PMID:25433721   PMID:25476740   PMID:25533286   PMID:25627620   PMID:25667414   PMID:25769888   PMID:25812350   PMID:25889297   PMID:25966773   PMID:25990390  
PMID:26004159   PMID:26109466   PMID:26116899   PMID:26121407   PMID:26161394   PMID:26359802   PMID:26385705   PMID:26517519   PMID:26752644   PMID:26908875   PMID:26927848   PMID:27212637  
PMID:27639935   PMID:27650493   PMID:27663978   PMID:27685937   PMID:27782867   PMID:27811371   PMID:27873133   PMID:27990444   PMID:28108506   PMID:28381538   PMID:28402859   PMID:28413701  
PMID:28661964   PMID:28859668   PMID:28931218   PMID:28972436   PMID:29085997   PMID:29338586   PMID:29482642   PMID:29541901   PMID:29661539   PMID:29675946   PMID:29705691   PMID:29728857  
PMID:29880013   PMID:29947047   PMID:29956754   PMID:30019153   PMID:30083887   PMID:30232328   PMID:30276608   PMID:30553016   PMID:30846990   PMID:31015152   PMID:31066256   PMID:31390578  
PMID:31523787   PMID:31573360   PMID:31628349   PMID:31634297   PMID:31699671   PMID:31702033   PMID:31886231   PMID:31978584   PMID:32047959   PMID:32213567   PMID:32480426   PMID:32584200  
PMID:32610209   PMID:32699279   PMID:32847038  


Genomics

Comparative Map Data
CXCL13
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl477,511,753 - 77,611,834 (+)EnsemblGRCh38hg38GRCh38
GRCh38477,511,753 - 77,611,834 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37478,432,907 - 78,532,988 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36478,651,931 - 78,752,010 (+)NCBINCBI36hg18NCBI36
Build 34478,790,084 - 78,890,165NCBI
Celera475,734,287 - 75,834,362 (+)NCBI
Cytogenetic Map4q21.1NCBI
HuRef474,184,783 - 74,284,964 (+)NCBIHuRef
CHM1_1478,409,854 - 78,509,941 (+)NCBICHM1_1
Cxcl13
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39596,104,798 - 96,108,927 (+)NCBIGRCm39mm39
GRCm39 Ensembl596,104,810 - 96,108,927 (+)Ensembl
GRCm38595,956,939 - 95,961,068 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl595,956,951 - 95,961,068 (+)EnsemblGRCm38mm10GRCm38
MGSCv37596,385,958 - 96,390,087 (+)NCBIGRCm37mm9NCBIm37
MGSCv36596,197,241 - 96,201,370 (+)NCBImm8
Celera593,306,539 - 93,310,668 (+)NCBICelera
Cytogenetic Map5E3NCBI
Cxcl13
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21413,608,894 - 13,613,965 (-)NCBI
Rnor_6.0 Ensembl1415,253,125 - 15,258,207 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01415,253,146 - 15,258,221 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01415,193,472 - 15,198,546 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41415,126,332 - 15,131,368 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1413,649,303 - 13,654,347 (-)NCBICelera
Cytogenetic Map14p22NCBI
Cxcl13
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554332,123,190 - 2,129,119 (+)NCBIChiLan1.0ChiLan1.0
CXCL13
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1452,428,702 - 52,434,803 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl452,428,702 - 52,434,803 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0446,583,759 - 46,589,865 (-)NCBIMhudiblu_PPA_v0panPan3
CXCL13
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1322,047,277 - 2,053,277 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl322,047,315 - 2,052,833 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3239,837,784 - 39,843,805 (-)NCBI
ROS_Cfam_1.0322,073,585 - 2,079,610 (+)NCBI
UMICH_Zoey_3.1322,071,444 - 2,077,479 (+)NCBI
UNSW_CanFamBas_1.0322,019,776 - 2,025,803 (+)NCBI
UU_Cfam_GSD_1.03238,148,529 - 38,154,567 (-)NCBI
Cxcl13
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528510,191,903 - 10,197,633 (-)NCBI
SpeTri2.0NW_0049366761,309,625 - 1,314,532 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CXCL13
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1873,071,261 - 73,077,342 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2877,268,254 - 77,274,314 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CXCL13
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1726,101,489 - 26,108,430 (+)NCBI
ChlSab1.1 Ensembl726,102,714 - 26,108,690 (+)Ensembl
Vero_WHO_p1.0NW_0236660374,454,575 - 4,460,831 (+)NCBI
Cxcl13
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475713,488,787 - 13,494,831 (-)NCBI

Position Markers
SHGC-59613  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37478,532,701 - 78,532,932UniSTSGRCh37
Build 36478,751,725 - 78,751,956RGDNCBI36
Celera475,834,075 - 75,834,306RGD
Cytogenetic Map4q21UniSTS
HuRef474,284,677 - 74,284,908UniSTS
GeneMap99-GB4 RH Map4437.5UniSTS
NCBI RH Map4903.2UniSTS
D4S3265  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37478,532,692 - 78,532,800UniSTSGRCh37
Build 36478,751,716 - 78,751,824RGDNCBI36
Celera475,834,066 - 75,834,174RGD
Cytogenetic Map4q21UniSTS
HuRef474,284,668 - 74,284,776UniSTS
TNG Radiation Hybrid Map445575.0UniSTS
Stanford-G3 RH Map44373.0UniSTS
GeneMap99-G3 RH Map44357.0UniSTS

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:487
Count of miRNA genes:308
Interacting mature miRNAs:331
Transcripts:ENST00000286758, ENST00000506590
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High 1 39 1 1 1
Medium 251 11 157 67 435 67 82 4 93 34 186 157 16 57 1
Low 780 285 651 268 203 189 1045 263 1288 129 704 493 80 1 303 699 3 1
Below cutoff 1111 1758 707 228 625 157 2164 1149 1570 155 405 636 71 667 1407 1

Sequence


Reference Sequences
RefSeq Acc Id: ENST00000286758   ⟹   ENSP00000286758
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl477,511,753 - 77,611,834 (+)Ensembl
RefSeq Acc Id: ENST00000506590
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl477,605,832 - 77,610,922 (+)Ensembl
RefSeq Acc Id: NM_001371558   ⟹   NP_001358487
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38477,605,820 - 77,611,834 (+)NCBI
RefSeq Acc Id: NM_006419   ⟹   NP_006410
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38477,511,753 - 77,611,834 (+)NCBI
GRCh37478,432,907 - 78,532,988 (+)ENTREZGENE
Build 36478,651,931 - 78,752,010 (+)NCBI Archive
HuRef474,184,783 - 74,284,964 (+)ENTREZGENE
CHM1_1478,409,854 - 78,509,941 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_006410   ⟸   NM_006419
- Peptide Label: precursor
- UniProtKB: O43927 (UniProtKB/Swiss-Prot),   Q53X90 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001358487   ⟸   NM_001371558
- Peptide Label: precursor
RefSeq Acc Id: ENSP00000286758   ⟸   ENST00000286758
Protein Domains
SCY

Promoters
RGD ID:6867798
Promoter ID:EPDNEW_H7064
Type:multiple initiation site
Name:CXCL13_1
Description:C-X-C motif chemokine ligand 13
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38477,605,820 - 77,605,880EPDNEW

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 4q21.1-21.23(chr4:75453111-84094295)x1 copy number loss See cases [RCV000050786] Chr4:75453111..84094295 [GRCh38]
Chr4:76378321..85015448 [GRCh37]
Chr4:76597345..85234472 [NCBI36]
Chr4:4q21.1-21.23
pathogenic
GRCh38/hg38 4q13.3-21.21(chr4:71128874-78099088)x3 copy number gain See cases [RCV000051774] Chr4:71128874..78099088 [GRCh38]
Chr4:71994591..79020242 [GRCh37]
Chr4:72213455..79239266 [NCBI36]
Chr4:4q13.3-21.21
pathogenic
GRCh38/hg38 4q12-22.3(chr4:51831622-97505618)x3 copy number gain See cases [RCV000051772] Chr4:51831622..97505618 [GRCh38]
Chr4:52697788..98426769 [GRCh37]
Chr4:52392545..98645792 [NCBI36]
Chr4:4q12-22.3
pathogenic
GRCh38/hg38 4q13.2-21.23(chr4:67869564-85517308)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053294]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053294]|See cases [RCV000053294] Chr4:67869564..85517308 [GRCh38]
Chr4:68735282..86438461 [GRCh37]
Chr4:68417877..86657485 [NCBI36]
Chr4:4q13.2-21.23
pathogenic
GRCh38/hg38 4q13.3-21.22(chr4:71079179-81802208)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053295]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053295]|See cases [RCV000053295] Chr4:71079179..81802208 [GRCh38]
Chr4:71944896..82723361 [GRCh37]
Chr4:72163760..82942385 [NCBI36]
Chr4:4q13.3-21.22
pathogenic
GRCh38/hg38 4q13.3-22.1(chr4:74031395-90421127)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053296]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053296]|See cases [RCV000053296] Chr4:74031395..90421127 [GRCh38]
Chr4:74897112..91342278 [GRCh37]
Chr4:75115976..91561301 [NCBI36]
Chr4:4q13.3-22.1
pathogenic
GRCh38/hg38 4q13.3-21.3(chr4:72262258-86002147)x3 copy number gain See cases [RCV000138312] Chr4:72262258..86002147 [GRCh38]
Chr4:73127975..86923300 [GRCh37]
Chr4:73346839..87142324 [NCBI36]
Chr4:4q13.3-21.3
pathogenic
GRCh38/hg38 4q21.1-21.21(chr4:75801143-79005805)x3 copy number gain See cases [RCV000141486] Chr4:75801143..79005805 [GRCh38]
Chr4:76722296..79926959 [GRCh37]
Chr4:76941320..80145983 [NCBI36]
Chr4:4q21.1-21.21
pathogenic
GRCh38/hg38 4q13.2-22.3(chr4:68686088-95294456)x3 copy number gain See cases [RCV000143458] Chr4:68686088..95294456 [GRCh38]
Chr4:69551806..96215607 [GRCh37]
Chr4:69234401..96434630 [NCBI36]
Chr4:4q13.2-22.3
pathogenic
GRCh37/hg19 4p16.3-q35.2(chr4:12440-190904441)x3 copy number gain See cases [RCV000446653] Chr4:12440..190904441 [GRCh37]
Chr4:4p16.3-q35.2
pathogenic
GRCh37/hg19 4p16.3-q35.2(chr4:68346-190957473) copy number gain See cases [RCV000510453] Chr4:68346..190957473 [GRCh37]
Chr4:4p16.3-q35.2
pathogenic
GRCh37/hg19 4p16.3-q35.2(chr4:68346-190957473)x3 copy number gain See cases [RCV000512241] Chr4:68346..190957473 [GRCh37]
Chr4:4p16.3-q35.2
pathogenic
GRCh37/hg19 4p16.3-q35.2(chr4:49450-190963766)x3 copy number gain not provided [RCV000743156] Chr4:49450..190963766 [GRCh37]
Chr4:4p16.3-q35.2
pathogenic
GRCh37/hg19 4p16.3-q35.2(chr4:11525-191028879)x3 copy number gain not provided [RCV000743147] Chr4:11525..191028879 [GRCh37]
Chr4:4p16.3-q35.2
pathogenic
GRCh37/hg19 4p16.3-q35.2(chr4:49450-190915650)x3 copy number gain not provided [RCV000743155] Chr4:49450..190915650 [GRCh37]
Chr4:4p16.3-q35.2
pathogenic
GRCh37/hg19 4q13.2-21.21(chr4:68950363-79738598)x1 copy number loss not provided [RCV001005553] Chr4:68950363..79738598 [GRCh37]
Chr4:4q13.2-21.21
pathogenic
GRCh37/hg19 4q13.3-21.23(chr4:72680879-86426232)x1 copy number loss not provided [RCV001005556] Chr4:72680879..86426232 [GRCh37]
Chr4:4q13.3-21.23
pathogenic
GRCh37/hg19 4q13.2-21.22(chr4:68242784-82991431)x3 copy number gain not provided [RCV000845944] Chr4:68242784..82991431 [GRCh37]
Chr4:4q13.2-21.22
pathogenic
GRCh37/hg19 4q21.1(chr4:78112981-78742412)x3 copy number gain not provided [RCV000846655] Chr4:78112981..78742412 [GRCh37]
Chr4:4q21.1
uncertain significance
GRCh37/hg19 4q13.3-21.3(chr4:71412409-87920784)x1 copy number loss See cases [RCV001263040] Chr4:71412409..87920784 [GRCh37]
Chr4:4q13.3-21.3
pathogenic

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:10639 AgrOrtholog
COSMIC CXCL13 COSMIC
Ensembl Genes ENSG00000156234 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSP00000286758 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000286758 ENTREZGENE, UniProtKB/Swiss-Prot
GTEx ENSG00000156234 GTEx
HGNC ID HGNC:10639 ENTREZGENE
Human Proteome Map CXCL13 Human Proteome Map
InterPro Chemokine_CXC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Chemokine_CXC_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Chemokine_IL8-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CXC_Chemokine_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Interleukin_8-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:10563 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 10563 ENTREZGENE
OMIM 605149 OMIM
PANTHER PTHR10179 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam IL8 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA35570 PharmGKB
PRINTS SMALLCYTKCXC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE SMALL_CYTOKINES_CXC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART SCY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF54117 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt CXL13_HUMAN UniProtKB/Swiss-Prot
  L8E878_HUMAN UniProtKB/TrEMBL
  O43927 ENTREZGENE
  Q53X90 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary A0A024RDB7 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-03-07 CXCL13  C-X-C motif chemokine ligand 13  CXCL13  chemokine (C-X-C motif) ligand 13  Symbol and/or name change 5135510 APPROVED