CALM1 (calmodulin 1) - Rat Genome Database

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Gene: CALM1 (calmodulin 1) Homo sapiens
Analyze
Symbol: CALM1
Name: calmodulin 1
RGD ID: 735369
HGNC Page HGNC:1442
Description: Enables several functions, including calcium channel inhibitor activity; enzyme activator activity; and enzyme binding activity. Involved in several processes, including cellular response to cytokine stimulus; regulation of calcium ion transmembrane transport; and regulation of heart contraction. Located in microtubule cytoskeleton and sarcomere. Part of calcium channel complex and catalytic complex. Implicated in catecholaminergic polymorphic ventricular tachycardia 4 and long QT syndrome 14. Biomarker of Alzheimer's disease.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: CALM2; CALM3; CALML2; calmodulin; calmodulin 1 (phosphorylase kinase, delta); calmodulin-1; Calmodulin-2; Calmodulin-3; caM; CAM2; CAM3; CAMB; CAMC; CAMI; CAMIII; CPVT4; DD132; LQT14; PHKD; PHKD1; phosphorylase kinase subunit delta; phosphorylase kinase subunit delta 1; phosphorylase kinase, delta subunit; prepro-calmodulin 1
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: CALM1P1   CALM1P2  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381490,396,502 - 90,408,268 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1490,396,502 - 90,408,268 (+)EnsemblGRCh38hg38GRCh38
GRCh371490,862,846 - 90,874,612 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361489,933,126 - 89,944,363 (+)NCBINCBI36Build 36hg18NCBI36
Build 341489,933,129 - 89,944,148NCBI
Celera1470,910,477 - 70,921,767 (+)NCBICelera
Cytogenetic Map14q32.11NCBI
HuRef1471,038,153 - 71,049,443 (+)NCBIHuRef
CHM1_11490,801,276 - 90,812,578 (+)NCBICHM1_1
T2T-CHM13v2.01484,621,229 - 84,632,993 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
CALM1HumanAlzheimer's disease  IEP 13792493protein:decreased expression:cerebellar cortex:RGD 
CALM1Humantype 2 diabetes mellitus  ISOCalm1 (Rattus norvegicus)6892953mRNA:decreased expression:heartRGD 
1 to 20 of 28 rows
Object Symbol
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Reference
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Original Reference(s)
CALM1Humanachondrogenesis type IA  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Achondrogenesis and type IAClinVarPMID:28492532
CALM1Humancatecholaminergic polymorphic ventricular tachycardia  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Catecholaminergic polymorphic ventricular tachycardiaClinVarPMID:23040497 more ...
CALM1Humancatecholaminergic polymorphic ventricular tachycardia 1  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Catecholaminergic polymorphic ventricular tachycardia 1ClinVarPMID:23040497 more ...
CALM1Humancatecholaminergic polymorphic ventricular tachycardia 1  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Catecholaminergic polymorphic ventricular tachycardia 1ClinVarPMID:23040497 more ...
CALM1Humancatecholaminergic polymorphic ventricular tachycardia 4  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Catecholaminergic polymorphic ventricular tachycardia 4ClinVarPMID:23040497 more ...
CALM1Humancatecholaminergic polymorphic ventricular tachycardia 4  IAGP (Homo sapiens) more ...8554872ClinVar Annotator: match by term: Catecholaminergic polymorphic ventricular tachycardia 4ClinVarPMID:28492532
CALM1Humancatecholaminergic polymorphic ventricular tachycardia 4  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Catecholaminergic polymorphic ventricular tachycardia 4ClinVarPMID:23040497 and PMID:28492532
CALM1Humancatecholaminergic polymorphic ventricular tachycardia 4  IAGP (Homo sapiens) more ...8554872ClinVar Annotator: match by term: Catecholaminergic polymorphic ventricular tachycardia 4ClinVarPMID:25741868 and PMID:28492532
CALM1Humancatecholaminergic polymorphic ventricular tachycardia 4  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Catecholaminergic polymorphic ventricular tachycardia 4ClinVarPMID:23040497 more ...
CALM1Humancatecholaminergic polymorphic ventricular tachycardia 4  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Catecholaminergic polymorphic ventricular tachycardia 4ClinVarPMID:17576681 more ...
CALM1Humancatecholaminergic polymorphic ventricular tachycardia 4  IAGP (Homo sapiens) and (Homo sapiens)8554872ClinVar Annotator: match by term: Catecholaminergic polymorphic ventricular tachycardia 4ClinVarPMID:25741868
CALM1Humancatecholaminergic polymorphic ventricular tachycardia 4  IAGP (Homo sapiens) and (Homo sapiens)8554872ClinVar Annotator: match by term: Catecholaminergic polymorphic ventricular tachycardia 4ClinVarPMID:27374306 and PMID:28492532
CALM1Humancatecholaminergic polymorphic ventricular tachycardia 4  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Catecholaminergic polymorphic ventricular tachycardia 4ClinVarPMID:23040497 more ...
CALM1Humancatecholaminergic polymorphic ventricular tachycardia 4  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Catecholaminergic polymorphic ventricular tachycardia 4ClinVarPMID:11569915 more ...
CALM1Humancatecholaminergic polymorphic ventricular tachycardia 4  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Catecholaminergic polymorphic ventricular tachycardia 4ClinVarPMID:23388215 more ...
CALM1Humancatecholaminergic polymorphic ventricular tachycardia 4  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Catecholaminergic polymorphic ventricular tachycardia 4ClinVarPMID:23040497 more ...
CALM1HumanFamilial Ventricular Tachycardia  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Familial polymorphic ventricular tachycardiaClinVarPMID:23040497 more ...
CALM1Humanlong QT syndrome  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Long QT syndromeClinVarPMID:25741868 more ...
CALM1Humanlong QT syndrome 14  IAGP (Homo sapiens) and (Homo sapiens)8554872ClinVar Annotator: match by term: Long QT syndrome 14ClinVarPMID:25741868 and PMID:28492532
CALM1Humanlong QT syndrome 14  IAGP (Homo sapiens) more ...8554872ClinVar Annotator: match by term: Long QT syndrome 14ClinVarPMID:28492532
1 to 20 of 28 rows
Object Symbol
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Original Reference(s)
CALM1HumanAlzheimer's disease  EXP 11554173CTD Direct Evidence: marker/mechanismCTDPMID:11470324
CALM1Humancannabis abuse  EXP 11554173CTD Direct Evidence: marker/mechanismCTDPMID:17205118
CALM1HumanCocaine-Related Disorders  EXP 11554173CTD Direct Evidence: marker/mechanismCTDPMID:17205118
CALM1Humanphencyclidine abuse  EXP 11554173CTD Direct Evidence: marker/mechanismCTDPMID:17205118
CALM1HumanWeight Gain  EXP 11554173CTD Direct Evidence: marker/mechanismCTDPMID:19030233
Object Symbol
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Original Reference(s)
CALM1Humancatecholaminergic polymorphic ventricular tachycardia 4  IAGP 7240710 OMIM 
CALM1Humanlong QT syndrome 14  IAGP 7240710 OMIM 

1 to 20 of 198 rows

  
Object Symbol
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Original Reference(s)
CALM1Human(R)-lipoic acid multiple interactionsISOCalm1 (Rattus norvegicus)6480464Thioctic Acid inhibits the reaction [Cadmium results in decreased expression of CALM1 mRNA]CTDPMID:26165643
CALM1Human(S)-nicotine multiple interactionsISOCalm1 (Mus musculus)6480464[Nicotine co-treated with 1-Methyl-4-phenyl-1 more ...CTDPMID:20230807
CALM1Human1,2-dimethylhydrazine affects expressionISOCalm1 (Mus musculus)64804641 and 2-Dimethylhydrazine affects the expression of CALM1 mRNACTDPMID:22206623
CALM1Human1,2-dimethylhydrazine multiple interactionsISOCalm1 (Mus musculus)6480464[1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of CALM1 mRNACTDPMID:22206623
CALM1Human1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine decreases expressionISOCalm1 (Mus musculus)64804641-Methyl-4-phenyl-1 more ...CTDPMID:20230807
CALM1Human1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine multiple interactionsISOCalm1 (Mus musculus)6480464[Caffeine co-treated with 1-Methyl-4-phenyl-1 more ...CTDPMID:20230807
CALM1Human1-naphthyl isothiocyanate increases expressionISOCalm1 (Rattus norvegicus)64804641-Naphthylisothiocyanate results in increased expression of CALM1 mRNACTDPMID:30723492
CALM1Human17alpha-ethynylestradiol affects expressionISOCalm1 (Mus musculus)6480464Ethinyl Estradiol affects the expression of CALM1 mRNACTDPMID:17555576
CALM1Human17alpha-ethynylestradiol multiple interactionsISOCalm1 (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CALM1 mRNACTDPMID:17942748
CALM1Human17alpha-ethynylestradiol increases expressionISOCalm1 (Mus musculus)6480464Ethinyl Estradiol results in increased expression of CALM1 mRNACTDPMID:17942748
CALM1Human17beta-estradiol multiple interactionsEXP 6480464[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of CALM1 mRNACTDPMID:20823114
CALM1Human17beta-estradiol decreases expressionISOCalm1 (Mus musculus)6480464Estradiol results in decreased expression of CALM1 mRNACTDPMID:39298647
CALM1Human2,2',4,4',5,5'-hexachlorobiphenyl affects expressionEXP 64804642 more ...CTDPMID:20638727
CALM1Human2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISOCalm1 (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CALM1 mRNACTDPMID:17942748
CALM1Human2,3,7,8-tetrachlorodibenzodioxine affects expressionISOCalm1 (Rattus norvegicus)6480464Tetrachlorodibenzodioxin affects the expression of CALM1 mRNACTDPMID:34747641
CALM1Human2,4,6-trinitrotoluene affects expressionISOCalm1 (Rattus norvegicus)6480464Trinitrotoluene affects the expression of CALM1 mRNACTDPMID:21346803
CALM1Human2,4-dinitrotoluene affects expressionISOCalm1 (Rattus norvegicus)64804642 and 4-dinitrotoluene affects the expression of CALM1 mRNACTDPMID:21346803
CALM1Human2,6-dimethoxyphenol multiple interactionsEXP 6480464[Furaldehyde co-treated with pyrogallol 1 more ...CTDPMID:38598786
CALM1Human2,6-dinitrotoluene affects expressionISOCalm1 (Rattus norvegicus)64804642 and 6-dinitrotoluene affects the expression of CALM1 mRNACTDPMID:21346803
CALM1Human2-amino-14,16-dimethyloctadecan-3-ol increases expressionEXP 64804642-amino-14 and 16-dimethyloctadecan-3-ol results in increased expression of CALM1 proteinCTDPMID:32044396

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Biological Process
1 to 20 of 39 rows

  
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Original Reference(s)
CALM1Humanautophagosome membrane docking involved_inIDA 150520179 PMID:28890335UniProtPMID:28890335
CALM1Humancalcineurin-mediated signaling involved_inIDA 150520179 PMID:8631777BHF-UCLPMID:8631777
CALM1Humancellular response to interferon-beta involved_inIDA 150520179 PMID:35568036UniProtPMID:35568036
CALM1Humancellular response to type II interferon involved_inIDA 150520179 PMID:11972023UniProtPMID:11972023
CALM1Humandetection of calcium ion involved_inIMP 150520179 PMID:23040497BHF-UCLPMID:23040497
CALM1Humanestablishment of protein localization to membrane involved_inIEAUniProtKB:P0DP29 more ...150520179 EnsemblGO_REF:0000107
CALM1Humanestablishment of protein localization to mitochondrial membrane involved_inIEAUniProtKB:P0DP29 more ...150520179 EnsemblGO_REF:0000107
CALM1HumanG protein-coupled receptor signaling pathway involved_inTAS 150520179 PMID:10899953UniProtPMID:10899953
CALM1HumanG2/M transition of mitotic cell cycle acts_upstream_of_or_withinIEAUniProtKB:P0DP26 more ...150520179 EnsemblGO_REF:0000107
CALM1Humanlong-term synaptic potentiation involved_inTAS 150520179 PMID:20668654BHF-UCLPMID:20668654
CALM1Humanmitochondrion-endoplasmic reticulum membrane tethering involved_inIDA 150520179 PMID:28890335UniProtPMID:28890335
CALM1Humannegative regulation of calcium ion export across plasma membrane involved_inIEAUniProtKB:P0DP27 more ...150520179 EnsemblGO_REF:0000107
CALM1Humannegative regulation of calcium ion export across plasma membrane involved_inISSUniProtKB:P0DP27150520179 ARUK-UCLGO_REF:0000024
CALM1Humannegative regulation of high voltage-gated calcium channel activity involved_inIMP 150520179 PMID:31454269UniProtPMID:31454269
CALM1Humannegative regulation of ryanodine-sensitive calcium-release channel activity involved_inIDA 150520179 PMID:26164367UniProtPMID:26164367
CALM1Humanorganelle localization by membrane tethering involved_inIDA 150520179 PMID:28890335UniProtPMID:28890335
CALM1Humanpositive regulation of nitric-oxide synthase activity  ISOCalm1 (Rattus norvegicus)9068941 RGDPMID:20529840 and REF_RGD_ID:7241266
CALM1Humanpositive regulation of receptor signaling pathway via JAK-STAT involved_inIDA 150520179 PMID:11972023 and PMID:35568036UniProtPMID:11972023 and PMID:35568036
CALM1Humanpresynaptic endocytosis involved_inIEAUniProtKB:P0DP26 more ...150520179 EnsemblGO_REF:0000107
CALM1Humanregulation of calcium-mediated signaling acts_upstream_of_or_withinISSUniProtKB:P0DP27150520179 ARUK-UCLGO_REF:0000024
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Cellular Component
1 to 20 of 43 rows

  
Object Symbol
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Original Reference(s)
CALM1Humancalcium channel complex part_ofIDA 150520179 PMID:23040497BHF-UCLPMID:23040497
CALM1Humancalyx of Held is_active_inIEAUniProtKB:P0DP26 more ...150520179 EnsemblGO_REF:0000107
CALM1Humancatalytic complex part_ofIDA 150520179 PMID:11807546CAFAPMID:11807546
CALM1Humancell projection located_inIEAUniProtKB-KW:KW-0966150520179 UniProtGO_REF:0000043
CALM1Humancentrosome located_inIEAUniProtKB-SubCell:SL-0048150520179 UniProtGO_REF:0000044
CALM1Humancentrosome is_active_inIBAPANTHER:PTN008588806 more ...150520179 GO_CentralGO_REF:0000033
CALM1Humancentrosome located_inIDA 150520179 PMID:16760425UniProtPMID:16760425
CALM1Humancilium located_inIEAUniProtKB-KW:KW-0969150520179 UniProtGO_REF:0000043
CALM1Humancytoplasm located_inTAS 150520179 PMID:10899953UniProtPMID:10899953
CALM1Humancytoplasm is_active_inIBAMGI:103250 more ...150520179 GO_CentralGO_REF:0000033
CALM1Humancytoplasm located_inIEAUniProtKB-KW:KW-0963150520179 UniProtGO_REF:0000043
CALM1Humancytoplasm located_inIDA 150520179 PMID:27165696UniProtPMID:27165696
CALM1Humancytoskeleton located_inIEAUniProtKB-KW:KW-0206150520179 UniProtGO_REF:0000043
CALM1Humancytosol located_inTAS 150520179 ReactomeReactome:R-HSA-111966 more ...
CALM1Humanextracellular region located_inTAS 150520179 ReactomeReactome:R-HSA-482772
CALM1Humangrowth cone  ISOCalm1 (Rattus norvegicus)9068941 RGDPMID:7492944 and REF_RGD_ID:7241258
CALM1Humangrowth cone located_inIEAUniProtKB:P0DP29 more ...150520179 EnsemblGO_REF:0000107
CALM1Humanmembrane located_inIEAUniProtKB:P0DP27 more ...150520179 EnsemblGO_REF:0000107
CALM1Humanmembrane located_inISSUniProtKB:P0DP27150520179 ARUK-UCLGO_REF:0000024
CALM1Humanmitochondrial membrane located_inIEAUniProtKB:P0DP29 more ...150520179 EnsemblGO_REF:0000107
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Molecular Function
1 to 20 of 59 rows

  
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Original Reference(s)
CALM1Humanadenylate cyclase activator activity enablesIDA 150520179 PMID:11807546UniProtPMID:11807546
CALM1Humanadenylate cyclase binding enablesIPIUniProtKB:P40136150520179 PMID:11807546CAFAPMID:11807546
CALM1Humancalcium channel inhibitor activity enablesIDA 150520179 PMID:26969752UniProtPMID:26969752
CALM1Humancalcium channel regulator activity enablesIDA 150520179 PMID:20226167BHF-UCLPMID:20226167
CALM1Humancalcium ion binding enablesIDA 150520179 PMID:11807546 more ...UniProtPMID:11807546 more ...
CALM1Humancalcium ion binding enablesIBAFB:FBgn0000253 more ...150520179 GO_CentralGO_REF:0000033
CALM1Humancalcium ion binding enablesIEAInterPro:IPR002048150520179 InterProGO_REF:0000002
CALM1Humancalcium ion binding  ISOCalm1 (Rattus norvegicus)9068941 RGDPMID:15628869 more ...
CALM1Humancalcium ion binding enablesIEAUniProtKB:P0DP29 more ...150520179 EnsemblGO_REF:0000107
CALM1Humancalcium-dependent protein binding  ISOGrm4 (Rattus norvegicus)9068941 RGDPMID:21855531 and REF_RGD_ID:7207139
CALM1Humancalcium-dependent protein binding enablesIEAUniProtKB:P0DP27 more ...150520179 EnsemblGO_REF:0000107
CALM1Humancalcium-dependent protein binding enablesISSUniProtKB:P0DP27150520179 ARUK-UCLGO_REF:0000024
CALM1Humancalcium-dependent protein binding  ISOKCNQ2 (Homo sapiens)9068941 RGDPMID:12032157 and REF_RGD_ID:634683
CALM1Humancalcium-dependent protein binding  ISOGrm7 (Rattus norvegicus)9068941 RGDPMID:21855531 and REF_RGD_ID:7207139
CALM1Humankinase activity enablesIEAUniProtKB-KW:KW-0418150520179 UniProtGO_REF:0000043
CALM1Humanmetal ion binding enablesIEAUniProtKB-KW:KW-0479150520179 UniProtGO_REF:0000043
CALM1Humannitric-oxide synthase binding  ISOCalm1 (Rattus norvegicus)9068941 RGDPMID:20529840 and REF_RGD_ID:7241266
CALM1Humannitric-oxide synthase binding enablesIEAUniProtKB:P0DP29 more ...150520179 EnsemblGO_REF:0000107
CALM1Humannitric-oxide synthase regulator activity  ISOCalm1 (Rattus norvegicus)9068941 RGDPMID:20529840 and REF_RGD_ID:7241266
CALM1Humannitric-oxide synthase regulator activity enablesIEAUniProtKB:P0DP29 more ...150520179 EnsemblGO_REF:0000107
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RGD Manual Annotations


  

Imported Annotations - SMPDB

1 to 20 of 38 rows
Object Symbol
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Original Reference(s)
CALM1Humanacebutolol pharmacodynamics pathway  EXP 10402751 SMPDBSMP:00296
CALM1Humanadrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway   EXP 10402751 SMPDBSMP:00296
CALM1Humanamiodarone pharmacodynamics pathway  EXP 10402751 SMPDBSMP:00665
CALM1Humanamlodipine pharmacodynamics pathway  EXP 10402751 SMPDBSMP:00376
CALM1Humanatenolol pharmacodynamics pathway  EXP 10402751 SMPDBSMP:00298
CALM1Humanbetaxolol pharmacodynamics pathway  EXP 10402751 SMPDBSMP:00299
CALM1Humanbisoprolol pharmacodynamics pathway  EXP 10402751 SMPDBSMP:00300
CALM1Humanbupranolol drug pathway  EXP 10402751 SMPDBSMP:00670
CALM1Humanbupranolol pharmacodynamics pathway  EXP 10402751 SMPDBSMP:00670
CALM1Humancarvedilol pharmacodynamics pathway  EXP 10402751 SMPDBSMP:00367
CALM1Humandiltiazem pharmacodynamics pathway  EXP 10402751 SMPDBSMP:00359
CALM1Humandisopyramide pharmacodynamics pathway  EXP 10402751 SMPDBSMP:00325
CALM1Humandobutamine pharmacodynamics pathway  EXP 10402751 SMPDBSMP:00662
CALM1Humanesmolol pharmacodynamics pathway  EXP 10402751 SMPDBSMP:00301
CALM1Humanflecainde pharmacodynamics pathway  EXP 10402751 SMPDBSMP:00331
CALM1Humanfosphenytoin pharmacodynamics pathway  EXP 10402751 SMPDBSMP:00326
CALM1Humanibutilide pharmacodynamics pathway  EXP 10402751 SMPDBSMP:00332
CALM1Humanisoprenaline pharmacodynamics pathway  EXP 10402751 SMPDBSMP:00663
CALM1Humanisradipine pharmacodynamics pathway  EXP 10402751 SMPDBSMP:00378
CALM1Humanlevobunolol pharmacodynamics pathway  EXP 10402751 SMPDBSMP:00666
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Imported Annotations - KEGG (archival)

1 to 9 of 9 rows
Object Symbol
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Original Reference(s)
CALM1HumanAlzheimer's disease pathway   IEA 6907045 KEGGhsa:05010
CALM1Humanglioma pathway  IEA 6907045 KEGGhsa:05214
CALM1Humangonadotropin-releasing hormone signaling pathway  IEA 6907045 KEGGhsa:04912
CALM1Humaninsulin signaling pathway   IEA 6907045 KEGGhsa:04910
CALM1Humanlong term potentiation  IEA 6907045 KEGGhsa:04720
CALM1Humanneurotrophic factor signaling pathway  IEA 6907045 KEGGhsa:04722
CALM1Humanphosphatidylinositol 3-kinase signaling pathway  IEA 6907045 KEGGhsa:04070
CALM1Humantuberculosis pathway  IEA 6907045 KEGGhsa:05152
CALM1Humanvisual phototransduction pathway   IEA 6907045 KEGGhsa:04744
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Imported Annotations - PID (archival)

Object Symbol
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Original Reference(s)
CALM1Humaninsulin responsive facilitative sugar transporter mediated glucose transport pathway   EXP 6484113 PIDPID:200196
CALM1HumanN-cadherin signaling pathway  EXP 6484113 PIDPID:200209
CALM1Humanp38 MAPK signaling pathway   EXP 6484113 PIDPID:200018
CALM1Humantype II interferon signaling pathway  EXP 6484113 PIDPID:200129
CALM1Humanvascular endothelial growth factor signaling pathway   EXP 6484113 PIDPID:200188
1 to 20 of 46 rows
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Original Reference(s)
CALM1Human2:1 atrioventricular block  IAGP 8699517 HPOMIM:616247
CALM1HumanAbnormal autonomic nervous system physiology  IAGP 8699517 HPOORPHA:101016
CALM1HumanAbnormal cardiac exercise stress test  IAGP 8699517 HPOORPHA:101016
CALM1HumanAbnormal T-wave  IAGP 8699517 HPOORPHA:101016
CALM1HumanAbnormality of prenatal development or birth  IAGP 8699517 HPOORPHA:101016
CALM1HumanAtrial fibrillation  IAGP 8699517 HPOORPHA:3286
CALM1HumanAutosomal dominant inheritance  IAGP 8699517 HPOMIM:616247
CALM1HumanAutosomal dominant inheritance  IAGP 8699517 HPOMIM:614916
CALM1HumanCardiac arrest  IAGP 8699517 HPOORPHA:3286
CALM1HumanCardiac arrest  IAGP 8699517 HPOMIM:616247
CALM1HumanCardiac arrest  IAGP 8699517 HPOMIM:614916
CALM1HumanChildhood onset  IAGP 8699517 HPOMIM:616247
CALM1HumanChildhood onset  IAGP 8699517 HPOMIM:614916
CALM1HumanHearing impairment  IAGP 8699517 HPOORPHA:101016
CALM1HumanHypokalemia  IAGP 8699517 HPOORPHA:101016
CALM1HumanInfantile onset  IAGP 8699517 HPOMIM:616247
CALM1HumanJuvenile onset  IAGP 8699517 HPOMIM:614916
CALM1HumanMyocarditis  IAGP 8699517 HPOMIM:616247
CALM1HumanNeonatal onset  IAGP 8699517 HPOMIM:616247
CALM1HumanPalpitations  IAGP 8699517 HPOORPHA:3286
1 to 20 of 46 rows
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
CALM1HumanEffort-induced polymorphic ventricular tachycardia  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Catecholaminergic polymorphic ventricular tachycardiaClinVarPMID:23040497 more ...
CALM1HumanProlonged QT interval  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Long QT syndromeClinVarPMID:25741868 more ...

1 to 16 of 16 rows
#
Reference Title
Reference Citation
1. Phosphorylase kinase: the complexity of its regulation is reflected in the complexity of its structure. Brushia RJ and Walsh DA, Front Biosci. 1999 Sep 15;4:D618-41.
2. Calmodulin: a prototypical calcium sensor. Chin D and Means AR, Trends Cell Biol. 2000 Aug;10(8):322-8.
3. Calcium signaling. Clapham DE, Cell. 2007 Dec 14;131(6):1047-58.
4. CaMKII regulation in information processing and storage. Coultrap SJ and Bayer KU, Trends Neurosci. 2012 Oct;35(10):607-18. doi: 10.1016/j.tins.2012.05.003. Epub 2012 Jun 19.
5. Calmodulin-dependent protein kinase kinase-beta is an alternative upstream kinase for AMP-activated protein kinase. Hawley SA, etal., Cell Metab. 2005 Jul;2(1):9-19.
6. Changing pattern of gene expression is associated with ventricular myocyte dysfunction and altered mechanisms of Ca2+ signalling in young type 2 Zucker diabetic fatty rat heart. Howarth FC, etal., Exp Physiol. 2011 Mar;96(3):325-37. Epub 2011 Jan 7.
7. KEGG: Kyoto Encyclopedia of Genes and Genomes KEGG
8. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
9. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
10. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
11. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
12. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
13. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
14. RGD HPO Phenotype Annotation Pipeline RGD automated import pipeline for human HPO-to-gene-to-disease annotations
15. New therapeutic targets in cardiology: arrhythmias and Ca2+/calmodulin-dependent kinase II (CaMKII). Rokita AG and Anderson ME, Circulation. 2012 Oct 23;126(17):2125-39. doi: 10.1161/CIRCULATIONAHA.112.124990.
16. Immunostaining of calmodulin and aluminium in Alzheimer's disease-affected brains. Solomon B, etal., Brain Res Bull. 2001 May 15;55(2):253-6.
1 to 16 of 16 rows
1 to 10 of 52 rows
PMID:1332771   PMID:1519061   PMID:1520270   PMID:1544444   PMID:1660262   PMID:1790714   PMID:1872871   PMID:2062825   PMID:2123288   PMID:2161834   PMID:2223880   PMID:2445749  
PMID:2455687   PMID:2487274   PMID:2507540   PMID:2853949   PMID:3111527   PMID:3350007   PMID:3472906   PMID:6385987   PMID:6847627   PMID:7490111   PMID:7525583   PMID:7559563  
PMID:7593266   PMID:7607248   PMID:7642608   PMID:7836475   PMID:7887964   PMID:7925473   PMID:7947686   PMID:8206911   PMID:8226798   PMID:8312049   PMID:8314583   PMID:8486648  
PMID:8573130   PMID:8625412   PMID:8626479   PMID:8631777   PMID:8639568   PMID:8663089   PMID:8670801   PMID:8756646   PMID:8769426   PMID:8780394   PMID:8810259   PMID:8824319  
PMID:8862395   PMID:8872303   PMID:8900147   PMID:8901523   PMID:9003189   PMID:9009191   PMID:9092566   PMID:9096366   PMID:9115241   PMID:9115269   PMID:9188503   PMID:9202019  
PMID:9278050   PMID:9282777   PMID:9341188   PMID:9362478   PMID:9374536   PMID:9405457   PMID:9490638   PMID:9512352   PMID:9658102   PMID:9677319   PMID:9681195   PMID:9728925  
PMID:9753452   PMID:9774336   PMID:9822657   PMID:9837900   PMID:9923700   PMID:9952395   PMID:10026195   PMID:10026200   PMID:10075657   PMID:10075700   PMID:10088721   PMID:10333484  
PMID:10411641   PMID:10416864   PMID:10488094   PMID:10547355   PMID:10625668   PMID:10681496   PMID:10692436   PMID:10747990   PMID:10748158   PMID:10757985   PMID:10767429   PMID:10816571  
PMID:10823944   PMID:10827182   PMID:10852921   PMID:10860555   PMID:10880439   PMID:10893241   PMID:10899953   PMID:11054265   PMID:11072229   PMID:11118454   PMID:11171103   PMID:11178895  
PMID:11248124   PMID:11278607   PMID:11286509   PMID:11306590   PMID:11323678   PMID:11395482   PMID:11397791   PMID:11448995   PMID:11457836   PMID:11468167   PMID:11585916   PMID:11734550  
1 to 10 of 52 rows



CALM1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381490,396,502 - 90,408,268 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1490,396,502 - 90,408,268 (+)EnsemblGRCh38hg38GRCh38
GRCh371490,862,846 - 90,874,612 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361489,933,126 - 89,944,363 (+)NCBINCBI36Build 36hg18NCBI36
Build 341489,933,129 - 89,944,148NCBI
Celera1470,910,477 - 70,921,767 (+)NCBICelera
Cytogenetic Map14q32.11NCBI
HuRef1471,038,153 - 71,049,443 (+)NCBIHuRef
CHM1_11490,801,276 - 90,812,578 (+)NCBICHM1_1
T2T-CHM13v2.01484,621,229 - 84,632,993 (+)NCBIT2T-CHM13v2.0
Calm1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3912100,165,694 - 100,176,083 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl12100,165,694 - 100,176,073 (+)EnsemblGRCm39 Ensembl
GRCm3812100,199,435 - 100,209,824 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl12100,199,435 - 100,209,814 (+)EnsemblGRCm38mm10GRCm38
MGSCv3712101,437,751 - 101,448,016 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3612100,600,591 - 100,610,856 (+)NCBIMGSCv36mm8
Celera12101,426,181 - 101,436,442 (+)NCBICelera
Cytogenetic Map12ENCBI
cM Map1250.43NCBI
Calm1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86125,217,191 - 125,227,855 (+)NCBIGRCr8
mRatBN7.26119,487,691 - 119,495,759 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6119,487,621 - 119,498,227 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx6119,649,410 - 119,657,616 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06119,946,208 - 119,954,273 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06119,281,076 - 119,289,141 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06124,217,241 - 124,225,292 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6124,217,241 - 124,225,292 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06133,444,207 - 133,452,258 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46124,477,601 - 124,485,669 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.16124,481,414 - 124,491,549 (+)NCBI
Celera6117,015,915 - 117,023,918 (+)NCBICelera
Cytogenetic Map6q32NCBI
Calm1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543812,842,437 - 12,854,028 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543812,842,437 - 12,854,028 (+)NCBIChiLan1.0ChiLan1.0
CALM1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21591,541,950 - 91,553,249 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11490,758,463 - 90,769,755 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01471,015,099 - 71,026,322 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11490,367,086 - 90,378,361 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1952,121,687 - 52,131,135 (+)Ensemblpanpan1.1panPan2
CALM1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1861,398,231 - 61,408,874 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl861,398,244 - 61,406,195 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha860,978,989 - 60,989,622 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0861,672,887 - 61,680,835 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl861,672,892 - 61,683,535 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1861,353,922 - 61,364,539 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0861,402,765 - 61,413,376 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0861,731,734 - 61,739,644 (+)NCBIUU_Cfam_GSD_1.0
Calm1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864014,480,463 - 14,488,619 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648817,580,454 - 17,588,507 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648817,580,425 - 17,588,480 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CALM1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl7112,160,806 - 112,171,744 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.17112,160,823 - 112,171,754 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.27118,728,008 - 118,738,940 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CALM1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12468,133,446 - 68,145,117 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2468,133,428 - 68,145,180 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605355,415,057 - 55,426,335 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Calm1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473412,030,001 - 12,041,772 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473412,030,264 - 12,041,682 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

.
Variants in CALM1
144 total Variants

1 to 10 of 196 rows
Name
Type
Condition(s)
Position(s)
Clinical significance
NM_006888.6(CALM1):c.161A>T (p.Asn54Ile) single nucleotide variant Catecholaminergic polymorphic ventricular tachycardia 1 [RCV000157133]|Catecholaminergic polymorphic ventricular tachycardia 4 [RCV000032976] Chr14:90401385 [GRCh38]
Chr14:90867729 [GRCh37]
Chr14:14q32.11		 pathogenic|likely pathogenic
NM_006888.6(CALM1):c.293A>G (p.Asn98Ser) single nucleotide variant CALM1-related disorder [RCV004758616]|Cardiovascular phenotype [RCV002433484]|Catecholaminergic polymorphic ventricular tachycardia 1 [RCV000157134]|Catecholaminergic polymorphic ventricular tachycardia 4 [RCV000032977]|Catecholaminergic polymorphic ventricular tachycardia 4 [RCV000526484]|Catecholaminergic polymorphic ventricular tachycardia [RCV000714909] Chr14:90404386 [GRCh38]
Chr14:90870730 [GRCh37]
Chr14:14q32.11		 pathogenic|likely pathogenic|conflicting interpretations of pathogenicity
GRCh38/hg38 14q32.11-32.13(chr14:90255156-95274696)x1 copy number loss See cases [RCV000051551] Chr14:90255156..95274696 [GRCh38]
Chr14:90721500..95741033 [GRCh37]
Chr14:89791253..94810786 [NCBI36]
Chr14:14q32.11-32.13		 pathogenic
GRCh38/hg38 14q24.2-32.2(chr14:72787506-99596719)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052293]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052293]|See cases [RCV000052293] Chr14:72787506..99596719 [GRCh38]
Chr14:73254214..100063056 [GRCh37]
Chr14:72323967..99132809 [NCBI36]
Chr14:14q24.2-32.2		 pathogenic
GRCh38/hg38 14q31.3-32.33(chr14:86094030-106832642)x3 copy number gain See cases [RCV000052295] Chr14:86094030..106832642 [GRCh38]
Chr14:86560374..107240869 [GRCh37]
Chr14:85630127..106311914 [NCBI36]
Chr14:14q31.3-32.33		 pathogenic
GRCh38/hg38 14q24.3-32.33(chr14:73655772-106879298)x3 copy number gain See cases [RCV000134000] Chr14:73655772..106879298 [GRCh38]
Chr14:74122475..107287505 [GRCh37]
Chr14:73192228..106358550 [NCBI36]
Chr14:14q24.3-32.33		 pathogenic
GRCh38/hg38 14q11.2-32.33(chr14:20151149-106855263)x3 copy number gain See cases [RCV000135543] Chr14:20151149..106855263 [GRCh38]
Chr14:20619308..107263478 [GRCh37]
Chr14:19689148..106334523 [NCBI36]
Chr14:14q11.2-32.33		 pathogenic
GRCh38/hg38 14q24.3-32.33(chr14:77222795-106879298)x3 copy number gain See cases [RCV000138230] Chr14:77222795..106879298 [GRCh38]
Chr14:77689138..107287505 [GRCh37]
Chr14:76758891..106358550 [NCBI36]
Chr14:14q24.3-32.33		 pathogenic
GRCh38/hg38 14q11.2-32.33(chr14:20043514-106877229)x3 copy number gain See cases [RCV000143373] Chr14:20043514..106877229 [GRCh38]
Chr14:20511673..107285437 [GRCh37]
Chr14:19581513..106356482 [NCBI36]
Chr14:14q11.2-32.33		 pathogenic
GRCh38/hg38 14q31.2-32.33(chr14:83912345-106855405)x3 copy number gain See cases [RCV000052294] Chr14:83912345..106855405 [GRCh38]
Chr14:84378689..107263620 [GRCh37]
Chr14:83448442..106334665 [NCBI36]
Chr14:14q31.2-32.33		 pathogenic
1 to 10 of 196 rows

Predicted Target Of
Summary Value
Count of predictions:3299
Count of miRNA genes:1105
Interacting mature miRNAs:1367
Transcripts:ENST00000356978, ENST00000447653, ENST00000544280, ENST00000553422, ENST00000553542, ENST00000553630, ENST00000553964, ENST00000553995, ENST00000554296, ENST00000555132, ENST00000555267, ENST00000556721, ENST00000556757, ENST00000557020, ENST00000557123
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

RH70561  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371490,871,837 - 90,872,096UniSTSGRCh37
Build 361489,941,590 - 89,941,849RGDNCBI36
Celera1470,918,985 - 70,919,245RGD
Cytogenetic Map14q32.11UniSTS
HuRef1471,046,661 - 71,046,921UniSTS
GeneMap99-GB4 RH Map14236.09UniSTS
RH11167  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371490,874,321 - 90,874,451UniSTSGRCh37
Build 361489,944,074 - 89,944,204RGDNCBI36
Celera1470,921,469 - 70,921,599RGD
Cytogenetic Map14q32.11UniSTS
HuRef1471,049,145 - 71,049,275UniSTS
GeneMap99-GB4 RH Map14236.19UniSTS
G54145  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371490,871,394 - 90,871,555UniSTSGRCh37
GRCh37X94,755,363 - 94,755,524UniSTSGRCh37
Build 36X94,642,019 - 94,642,180RGDNCBI36
CeleraX95,279,996 - 95,280,157RGD
Celera1470,918,542 - 70,918,703UniSTS
Cytogenetic Map14q32.11UniSTS
HuRef1471,046,218 - 71,046,379UniSTS
D14S89E  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371490,872,605 - 90,872,797UniSTSGRCh37
GRCh371490,872,763 - 90,872,862UniSTSGRCh37
GRCh371490,872,536 - 90,872,629UniSTSGRCh37
Build 361489,942,516 - 89,942,615RGDNCBI36
Celera1470,919,753 - 70,919,945UniSTS
Celera1470,919,684 - 70,919,777UniSTS
Celera1470,919,911 - 70,920,010RGD
Cytogenetic Map14q32.11UniSTS
HuRef1471,047,429 - 71,047,621UniSTS
HuRef1471,047,360 - 71,047,453UniSTS
HuRef1471,047,587 - 71,047,686UniSTS
TNG Radiation Hybrid Map1435712.0UniSTS
Stanford-G3 RH Map143193.0UniSTS
NCBI RH Map14940.2UniSTS
GeneMap99-G3 RH Map143742.0UniSTS
D14S98E  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371490,872,077 - 90,872,154UniSTSGRCh37
GRCh371490,871,958 - 90,872,197UniSTSGRCh37
Build 361489,941,830 - 89,941,907RGDNCBI36
Celera1470,919,226 - 70,919,303RGD
Celera1470,919,107 - 70,919,346UniSTS
Cytogenetic Map14q32.11UniSTS
HuRef1471,046,902 - 71,046,979UniSTS
HuRef1471,046,783 - 71,047,022UniSTS
TNG Radiation Hybrid Map1435712.0UniSTS
Stanford-G3 RH Map143186.0UniSTS
NCBI RH Map14939.8UniSTS
GeneMap99-G3 RH Map143735.0UniSTS
D14S642E  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371490,872,540 - 90,872,644UniSTSGRCh37
Build 361489,942,293 - 89,942,397RGDNCBI36
Celera1470,919,688 - 70,919,792RGD
Cytogenetic Map14q32.11UniSTS
HuRef1471,047,364 - 71,047,468UniSTS
GeneMap99-GB4 RH Map14236.19UniSTS
RH130082  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371490,874,452 - 90,874,602UniSTSGRCh37
Build 361489,944,205 - 89,944,355RGDNCBI36
Celera1470,921,600 - 70,921,750RGD
HuRef1471,049,276 - 71,049,426UniSTS
SSC3C06  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371490,874,325 - 90,874,528UniSTSGRCh37
Build 361489,944,078 - 89,944,281RGDNCBI36
Celera1470,921,473 - 70,921,676RGD
HuRef1471,049,149 - 71,049,352UniSTS
G06214  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371490,874,133 - 90,874,340UniSTSGRCh37
Build 361489,943,886 - 89,944,093RGDNCBI36
Celera1470,921,281 - 70,921,488RGD
Cytogenetic Map14q32.11UniSTS
HuRef1471,048,957 - 71,049,164UniSTS
RH11243  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371490,874,191 - 90,874,340UniSTSGRCh37
Build 361489,943,944 - 89,944,093RGDNCBI36
Celera1470,921,339 - 70,921,488RGD
Cytogenetic Map14q32.11UniSTS
HuRef1471,049,015 - 71,049,164UniSTS
GeneMap99-GB4 RH Map14236.19UniSTS
NCBI RH Map14935.0UniSTS
SHGC-30527  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371490,872,085 - 90,872,234UniSTSGRCh37
Build 361489,941,838 - 89,941,987RGDNCBI36
Celera1470,919,234 - 70,919,383RGD
Cytogenetic Map14q32.11UniSTS
HuRef1471,046,910 - 71,047,059UniSTS
TNG Radiation Hybrid Map1435712.0UniSTS
GeneMap99-GB4 RH Map14236.09UniSTS
Whitehead-RH Map14313.7UniSTS
GeneMap99-G3 RH Map143720.0UniSTS
WI-18834  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371490,871,536 - 90,871,678UniSTSGRCh37
Build 361489,941,289 - 89,941,431RGDNCBI36
Celera1470,918,684 - 70,918,826RGD
Cytogenetic Map14q32.11UniSTS
HuRef1471,046,360 - 71,046,502UniSTS
GeneMap99-GB4 RH Map14236.19UniSTS
Whitehead-RH Map14313.7UniSTS
D14S901  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371490,874,194 - 90,874,295UniSTSGRCh37
Build 361489,943,947 - 89,944,048RGDNCBI36
Celera1470,921,342 - 70,921,443RGD
Cytogenetic Map14q32.11UniSTS
HuRef1471,049,018 - 71,049,119UniSTS
GeneMap99-GB4 RH Map14235.8UniSTS
NCBI RH Map14935.0UniSTS
1928  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371490,872,635 - 90,872,735UniSTSGRCh37
Build 361489,942,388 - 89,942,488RGDNCBI36
Celera1470,919,783 - 70,919,883RGD
Cytogenetic Map14q32.11UniSTS
HuRef1471,047,459 - 71,047,559UniSTS
GeneMap99-GB4 RH Map14235.99UniSTS
NCBI RH Map14935.0UniSTS
IB3608  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371490,874,435 - 90,874,600UniSTSGRCh37
Build 361489,944,188 - 89,944,353RGDNCBI36
Celera1470,921,583 - 70,921,748RGD
Cytogenetic Map14q32.11UniSTS
HuRef1471,049,259 - 71,049,424UniSTS
GeneMap99-GB4 RH Map14236.19UniSTS
Whitehead-RH Map14313.6UniSTS
D14S1231  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371490,872,642 - 90,872,750UniSTSGRCh37
Build 361489,942,395 - 89,942,503RGDNCBI36
Celera1470,919,790 - 70,919,898RGD
Cytogenetic Map14q32.11UniSTS
HuRef1471,047,466 - 71,047,574UniSTS
Whitehead-YAC Contig Map14 UniSTS
EST13B3  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371490,874,306 - 90,874,516UniSTSGRCh37
Build 361489,944,059 - 89,944,269RGDNCBI36
Celera1470,921,454 - 70,921,664RGD
HuRef1471,049,130 - 71,049,340UniSTS
GDB:433805  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371490,870,220 - 90,870,786UniSTSGRCh37
Celera1470,917,368 - 70,917,934UniSTS
Cytogenetic Map14q32.11UniSTS
HuRef1471,045,044 - 71,045,610UniSTS
CALM1  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371490,871,084 - 90,871,908UniSTSGRCh37
Celera1470,918,232 - 70,919,056UniSTS
HuRef1471,046,215 - 71,046,365UniSTS
HuRef1471,045,908 - 71,046,732UniSTS
D14S98E  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map14q32.11UniSTS
D14S89E  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map14q32.11UniSTS
D14S89E  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map14q32.11UniSTS
TNG Radiation Hybrid Map1435712.0UniSTS
Stanford-G3 RH Map143193.0UniSTS
NCBI RH Map14940.2UniSTS
GeneMap99-G3 RH Map143742.0UniSTS
CALM1  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371490,871,084 - 90,871,908UniSTSGRCh37
Celera1470,918,232 - 70,919,056UniSTS
HuRef1471,046,215 - 71,046,365UniSTS
HuRef1471,045,908 - 71,046,732UniSTS




adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
sensory system
2408 4430 5572 4392 8976 2840 3404 776 2366 452 3936 11556 11200 7088 1022 2790 2462 324


1 to 27 of 27 rows
RefSeq Transcripts NG_013338 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001363669 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001363670 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_006888 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC006536 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH005370 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH005375 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI651063 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK289937 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL512791 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AU122722 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY189287 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC000454 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC007965 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC008597 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC011834 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC042831 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC047523 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BT006818 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX479707 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX482177 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX537677 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX648223 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471061 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068264 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DA059080 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M27319 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
1 to 27 of 27 rows

Ensembl Acc Id: ENST00000356978   ⟹   ENSP00000349467
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1490,397,029 - 90,408,268 (+)Ensembl
Ensembl Acc Id: ENST00000447653   ⟹   ENSP00000403491
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1490,397,029 - 90,405,072 (+)Ensembl
Ensembl Acc Id: ENST00000544280   ⟹   ENSP00000442853
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1490,398,262 - 90,405,107 (+)Ensembl
Ensembl Acc Id: ENST00000553422   ⟹   ENSP00000450425
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1490,401,333 - 90,404,833 (+)Ensembl
Ensembl Acc Id: ENST00000553542   ⟹   ENSP00000450829
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1490,397,056 - 90,405,048 (+)Ensembl
Ensembl Acc Id: ENST00000553630   ⟹   ENSP00000451646
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1490,397,040 - 90,405,603 (+)Ensembl
Ensembl Acc Id: ENST00000553964
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1490,397,932 - 90,404,807 (+)Ensembl
Ensembl Acc Id: ENST00000553995
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1490,397,032 - 90,404,067 (+)Ensembl
Ensembl Acc Id: ENST00000554296
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1490,403,632 - 90,404,746 (+)Ensembl
Ensembl Acc Id: ENST00000555132
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1490,397,032 - 90,398,803 (+)Ensembl
Ensembl Acc Id: ENST00000555267
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1490,399,978 - 90,404,153 (+)Ensembl
Ensembl Acc Id: ENST00000556721
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1490,404,168 - 90,404,785 (+)Ensembl
Ensembl Acc Id: ENST00000556757
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1490,397,032 - 90,401,613 (+)Ensembl
Ensembl Acc Id: ENST00000557020   ⟹   ENSP00000451062
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1490,396,502 - 90,404,496 (+)Ensembl
Ensembl Acc Id: ENST00000557123
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1490,397,032 - 90,400,431 (+)Ensembl
Ensembl Acc Id: ENST00000626705   ⟹   ENSP00000486402
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1490,397,032 - 90,405,607 (+)Ensembl
Ensembl Acc Id: ENST00000659177   ⟹   ENSP00000499421
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1490,397,692 - 90,404,760 (+)Ensembl
Ensembl Acc Id: ENST00000663135   ⟹   ENSP00000499498
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1490,399,065 - 90,404,965 (+)Ensembl
RefSeq Acc Id: NM_001363669   ⟹   NP_001350598
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381490,396,502 - 90,408,268 (+)NCBI
T2T-CHM13v2.01484,621,229 - 84,632,993 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001363670   ⟹   NP_001350599
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381490,398,167 - 90,408,268 (+)NCBI
T2T-CHM13v2.01484,622,894 - 84,632,993 (+)NCBI
Sequence:
RefSeq Acc Id: NM_006888   ⟹   NP_008819
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381490,397,029 - 90,408,268 (+)NCBI
GRCh371490,863,327 - 90,874,619 (+)ENTREZGENE
Build 361489,933,126 - 89,944,363 (+)NCBI Archive
HuRef1471,038,153 - 71,049,443 (+)ENTREZGENE
CHM1_11490,801,276 - 90,812,578 (+)NCBI
T2T-CHM13v2.01484,621,756 - 84,632,993 (+)NCBI
Sequence:
1 to 5 of 13 rows
1 to 5 of 13 rows
RefSeq Acc Id: NP_008819   ⟸   NM_006888
- Peptide Label: isoform 2
- UniProtKB: Q61380 (UniProtKB/Swiss-Prot),   Q61379 (UniProtKB/Swiss-Prot),   Q53S29 (UniProtKB/Swiss-Prot),   Q13942 (UniProtKB/Swiss-Prot),   P99014 (UniProtKB/Swiss-Prot),   P70667 (UniProtKB/Swiss-Prot),   P62158 (UniProtKB/Swiss-Prot),   P02593 (UniProtKB/Swiss-Prot),   Q96HK3 (UniProtKB/Swiss-Prot),   P0DP25 (UniProtKB/Swiss-Prot),   P0DP24 (UniProtKB/Swiss-Prot),   P0DP23 (UniProtKB/Swiss-Prot),   B4DJ51 (UniProtKB/TrEMBL),   B2RDW0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001350598   ⟸   NM_001363669
- Peptide Label: isoform 3
- UniProtKB: H0Y7A7 (UniProtKB/TrEMBL),   A0A9K3Y7M0 (UniProtKB/TrEMBL),   D6W5B3 (UniProtKB/TrEMBL),   E7ETZ0 (UniProtKB/TrEMBL),   Q96HY3 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001350599   ⟸   NM_001363670
- Peptide Label: isoform 1
- UniProtKB: B2RDW0 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSP00000451062   ⟸   ENST00000557020
Ensembl Acc Id: ENSP00000442853   ⟸   ENST00000544280
EF-hand

Name Modeler Protein Id AA Range Protein Structure
AF-P0DP23-F1-model_v2 AlphaFold P0DP23 1-149 view protein structure
AF-P0DP24-F1-model_v2 AlphaFold P0DP24 1-149 view protein structure
AF-P0DP25-F1-model_v2 AlphaFold P0DP25 1-149 view protein structure

RGD ID:6791353
Promoter ID:HG_KWN:19989
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:NM_006888,   UC010ATQ.1,   UC010ATR.1
Position:
Human AssemblyChrPosition (strand)Source
Build 361489,932,861 - 89,933,361 (+)MPROMDB
RGD ID:6851192
Promoter ID:EP73392
Type:single initiation site
Name:HS_CALM1
Description:Calmodulin 1 (phosphorylase kinase, delta).
SO ACC ID:SO:0000170
Source:EPD (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:NEDO full length human cDNA sequencing project.; Oligo-capping
Position:
Human AssemblyChrPosition (strand)Source
Build 361489,933,129 - 89,933,189EPD
RGD ID:6791352
Promoter ID:HG_KWN:19990
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:NM_001166106
Position:
Human AssemblyChrPosition (strand)Source
Build 361489,933,801 - 89,934,747 (+)MPROMDB
RGD ID:6810672
Promoter ID:HG_ACW:24086
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell_12Hour
Transcripts:CALM1.JAPR07,   SHOPAR.AAPR07-UNSPLICED
Position:
Human AssemblyChrPosition (strand)Source
Build 361489,937,161 - 89,937,661 (+)MPROMDB
RGD ID:7228361
Promoter ID:EPDNEW_H19926
Type:initiation region
Name:CALM1_1
Description:calmodulin 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381490,397,029 - 90,397,089EPDNEW


1 to 40 of 68 rows
Database
Acc Id
Source(s)
COSMIC CALM1 COSMIC
Ensembl Genes ENSG00000143933 UniProtKB/Swiss-Prot
  ENSG00000160014 UniProtKB/Swiss-Prot
  ENSG00000198668 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000272298.12 UniProtKB/Swiss-Prot
  ENST00000291295.14 UniProtKB/Swiss-Prot
  ENST00000356978 ENTREZGENE
  ENST00000356978.9 UniProtKB/Swiss-Prot
  ENST00000544280 ENTREZGENE
  ENST00000596362.1 UniProtKB/Swiss-Prot
Gene3D-CATH EF-hand UniProtKB/Swiss-Prot
GTEx ENSG00000143933 GTEx
  ENSG00000160014 GTEx
  ENSG00000198668 GTEx
HGNC ID HGNC:1442 ENTREZGENE
Human Proteome Map CALM1 Human Proteome Map
InterPro CALM/Myosin/TropC-like UniProtKB/Swiss-Prot
  EF-hand-dom_pair UniProtKB/Swiss-Prot
  EF_Hand_1_Ca_BS UniProtKB/Swiss-Prot
  EF_hand_dom UniProtKB/Swiss-Prot
KEGG Report hsa:801 UniProtKB/Swiss-Prot
  hsa:805 UniProtKB/Swiss-Prot
  hsa:808 UniProtKB/Swiss-Prot
NCBI Gene 801 ENTREZGENE
OMIM 114180 OMIM
PANTHER CALMODULIN LIKE 3 UniProtKB/Swiss-Prot
  MYOSIN LIGHT CHAIN 1, 3 UniProtKB/Swiss-Prot
Pfam EF-hand_7 UniProtKB/Swiss-Prot
PharmGKB PA26035 PharmGKB
PRINTS RECOVERIN UniProtKB/Swiss-Prot
PROSITE EF_HAND_1 UniProtKB/Swiss-Prot
  EF_HAND_2 UniProtKB/Swiss-Prot
SMART EFh UniProtKB/Swiss-Prot
Superfamily-SCOP SSF47473 UniProtKB/Swiss-Prot
UniProt A0A9K3Y7M0 ENTREZGENE
  B2RDW0 ENTREZGENE, UniProtKB/TrEMBL
  B4DJ51 ENTREZGENE, UniProtKB/TrEMBL
  CALM1_HUMAN UniProtKB/Swiss-Prot
  CALM2_HUMAN UniProtKB/Swiss-Prot
  CALM3_HUMAN UniProtKB/Swiss-Prot
1 to 40 of 68 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-06-30 CALM1  calmodulin 1    calmodulin 1 (phosphorylase kinase, delta)  Symbol and/or name change 5135510 APPROVED