CALM1 (calmodulin 1) - Rat Genome Database

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Gene: CALM1 (calmodulin 1) Pan paniscus
Analyze
Symbol: CALM1 (Ensembl: CALM3)
Name: calmodulin 1 (Ensembl:calmodulin 3)
RGD ID: 11706332
Description: ENCODES a protein that exhibits calcium channel inhibitor activity (ortholog); calcium ion binding (ortholog); calcium-dependent protein binding (ortholog); INVOLVED IN autophagosome membrane docking (ortholog); cellular response to interferon-beta (ortholog); cellular response to type II interferon (ortholog); PARTICIPATES IN acebutolol pharmacodynamics pathway; adenosine monophosphate-activated protein kinase (AMPK) signaling pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; ASSOCIATED WITH achondrogenesis type IA (ortholog); Alzheimer's disease (ortholog); cannabis abuse (ortholog); FOUND IN calyx of Held (ortholog); cytoplasm (ortholog); growth cone (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: calmodulin; calmodulin-1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21591,541,950 - 91,553,249 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11490,758,463 - 90,769,755 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01471,015,099 - 71,026,322 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11490,367,086 - 90,378,361 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1952,121,687 - 52,131,135 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
acebutolol pharmacodynamics pathway   (ISO)
adenosine monophosphate-activated protein kinase (AMPK) signaling pathway   (ISO)
adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway  (ISO)
amiodarone pharmacodynamics pathway  (ISO)
amlodipine pharmacodynamics pathway  (ISO)
atenolol pharmacodynamics pathway  (ISO)
betaxolol pharmacodynamics pathway  (ISO)
bisoprolol pharmacodynamics pathway  (ISO)
bupranolol drug pathway  (ISO)
bupranolol pharmacodynamics pathway   (ISO)
calcium/calcium-mediated signaling pathway   (ISO)
calcium/calmodulin dependent kinase 2 signaling pathway  (ISO)
carvedilol pharmacodynamics pathway  (ISO)
diltiazem pharmacodynamics pathway  (ISO)
disopyramide pharmacodynamics pathway  (ISO)
dobutamine pharmacodynamics pathway  (ISO)
esmolol pharmacodynamics pathway  (ISO)
flecainde pharmacodynamics pathway  (ISO)
fosphenytoin pharmacodynamics pathway   (ISO)
glycogen degradation pathway  (ISO)
ibutilide pharmacodynamics pathway   (ISO)
insulin responsive facilitative sugar transporter mediated glucose transport pathway  (ISO)
isoprenaline pharmacodynamics pathway  (ISO)
isradipine pharmacodynamics pathway  (ISO)
levobunolol pharmacodynamics pathway  (ISO)
lidocaine pharmacodynamics pathway  (ISO)
metoprolol pharmacodynamics pathway  (ISO)
mexiletine pharmacodynamics pathway  (ISO)
N-cadherin signaling pathway  (ISO)
nadolol pharmacodynamics pathway  (ISO)
nebivolol pharmacodynamics pathway  (ISO)
nifedipine pharmacodynamics pathway  (ISO)
nimodipine pharmacodynamics pathway  (ISO)
nisoldipine pharmacodynamics pathway  (ISO)
nitrendipine pharmacodynamics pathway   (ISO)
p38 MAPK signaling pathway  (ISO)
penbutolol pharmacodynamics pathway  (ISO)
phenytoin pharmacodynamics pathway  (ISO)
pindolol pharmacodynamics pathway  (ISO)
procainamide pharmacodynamics pathway  (ISO)
propranolol pharmacodynamics pathway  (ISO)
quinidine pharmacodynamics pathway  (ISO)
sotalol pharmacodynamics pathway  (ISO)
timolol pharmacodynamics pathway  (ISO)
type II interferon signaling pathway   (ISO)
vascular endothelial growth factor signaling pathway  (ISO)
verapamil pharmacodynamics pathway  (ISO)

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
CALM1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21591,541,950 - 91,553,249 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11490,758,463 - 90,769,755 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01471,015,099 - 71,026,322 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11490,367,086 - 90,378,361 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1952,121,687 - 52,131,135 (+)Ensemblpanpan1.1panPan2
CALM1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381490,396,502 - 90,408,268 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1490,396,502 - 90,408,268 (+)EnsemblGRCh38hg38GRCh38
GRCh371490,862,846 - 90,874,612 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361489,933,126 - 89,944,363 (+)NCBINCBI36Build 36hg18NCBI36
Build 341489,933,129 - 89,944,148NCBI
Celera1470,910,477 - 70,921,767 (+)NCBICelera
Cytogenetic Map14q32.11NCBI
HuRef1471,038,153 - 71,049,443 (+)NCBIHuRef
CHM1_11490,801,276 - 90,812,578 (+)NCBICHM1_1
T2T-CHM13v2.01484,621,229 - 84,632,993 (+)NCBIT2T-CHM13v2.0
Calm1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3912100,165,694 - 100,176,083 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl12100,165,694 - 100,176,073 (+)EnsemblGRCm39 Ensembl
GRCm3812100,199,435 - 100,209,824 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl12100,199,435 - 100,209,814 (+)EnsemblGRCm38mm10GRCm38
MGSCv3712101,437,751 - 101,448,016 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3612100,600,591 - 100,610,856 (+)NCBIMGSCv36mm8
Celera12101,426,181 - 101,436,442 (+)NCBICelera
Cytogenetic Map12ENCBI
cM Map1250.43NCBI
Calm1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86125,217,191 - 125,227,855 (+)NCBIGRCr8
mRatBN7.26119,487,691 - 119,495,759 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6119,487,621 - 119,498,227 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx6119,649,410 - 119,657,616 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06119,946,208 - 119,954,273 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06119,281,076 - 119,289,141 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06124,217,241 - 124,225,292 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6124,217,241 - 124,225,292 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06133,444,207 - 133,452,258 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46124,477,601 - 124,485,669 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.16124,481,414 - 124,491,549 (+)NCBI
Celera6117,015,915 - 117,023,918 (+)NCBICelera
Cytogenetic Map6q32NCBI
Calm1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543812,842,437 - 12,854,028 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543812,842,437 - 12,854,028 (+)NCBIChiLan1.0ChiLan1.0
CALM1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1861,398,231 - 61,408,874 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl861,398,244 - 61,406,195 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha860,978,989 - 60,989,622 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0861,672,887 - 61,680,835 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl861,672,892 - 61,683,535 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1861,353,922 - 61,364,539 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0861,402,765 - 61,413,376 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0861,731,734 - 61,739,644 (+)NCBIUU_Cfam_GSD_1.0
Calm1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864014,480,463 - 14,488,619 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648817,580,454 - 17,588,507 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648817,580,425 - 17,588,480 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CALM1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl7112,160,806 - 112,171,744 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.17112,160,823 - 112,171,754 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.27118,728,008 - 118,738,940 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CALM1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12468,133,446 - 68,145,117 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2468,133,428 - 68,145,180 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605355,415,057 - 55,426,335 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Calm1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473412,030,001 - 12,041,772 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473412,030,264 - 12,041,682 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000038008   ⟹   ENSPPAP00000015318
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2A48,204,518 - 48,220,697 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000038013   ⟹   ENSPPAP00000015323
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2A48,205,131 - 48,211,645 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000052031   ⟹   ENSPPAP00000029183
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1952,121,687 - 52,131,135 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000052039   ⟹   ENSPPAP00000029191
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1952,121,799 - 52,129,507 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000052041   ⟹   ENSPPAP00000029193
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1952,122,572 - 52,129,507 (+)Ensembl
RefSeq Acc Id: XM_003832761   ⟹   XP_003832809
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21591,541,950 - 91,553,249 (+)NCBI
NHGRI_mPanPan11490,758,463 - 90,769,755 (+)NCBI
Mhudiblu_PPA_v01471,015,099 - 71,026,322 (+)NCBI
PanPan1.11490,367,107 - 90,378,361 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063596371   ⟹   XP_063452441
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21591,543,472 - 91,553,249 (+)NCBI
RefSeq Acc Id: XM_063596372   ⟹   XP_063452442
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21591,543,472 - 91,553,249 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_003832809   ⟸   XM_003832761
- Peptide Label: isoform X2
- UniProtKB: A0A2R9BIN3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSPPAP00000029183   ⟸   ENSPPAT00000052031
RefSeq Acc Id: ENSPPAP00000029191   ⟸   ENSPPAT00000052039
RefSeq Acc Id: ENSPPAP00000029193   ⟸   ENSPPAT00000052041
RefSeq Acc Id: ENSPPAP00000015323   ⟸   ENSPPAT00000038013
RefSeq Acc Id: ENSPPAP00000015318   ⟸   ENSPPAT00000038008
RefSeq Acc Id: XP_063452441   ⟸   XM_063596371
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063452442   ⟸   XM_063596372
- Peptide Label: isoform X1
Protein Domains
EF-hand


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000030799 Ensembl, UniProtKB/TrEMBL
  ENSPPAG00000037613 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000038008.1 UniProtKB/TrEMBL
  ENSPPAT00000038013.1 UniProtKB/TrEMBL
  ENSPPAT00000052031.1 UniProtKB/TrEMBL
  ENSPPAT00000052039.1 UniProtKB/TrEMBL
  ENSPPAT00000052041.1 UniProtKB/TrEMBL
Gene3D-CATH EF-hand UniProtKB/TrEMBL
InterPro EF-hand-dom_pair UniProtKB/TrEMBL
  EF_Hand_1_Ca_BS UniProtKB/TrEMBL
  EF_hand_dom UniProtKB/TrEMBL
KEGG Report pps:100968473 UniProtKB/TrEMBL
  pps:100977014 UniProtKB/TrEMBL
  pps:100980454 UniProtKB/TrEMBL
NCBI Gene CALM1 ENTREZGENE
PANTHER AT10229P-RELATED UniProtKB/TrEMBL
  CALCIUM BINDING PROTEIN UniProtKB/TrEMBL
  CALMODULIN-1 UniProtKB/TrEMBL
Pfam EF-hand_7 UniProtKB/TrEMBL
PRINTS F138DOMAIN UniProtKB/TrEMBL
  RECOVERIN UniProtKB/TrEMBL
PROSITE EF_HAND_1 UniProtKB/TrEMBL
  EF_HAND_2 UniProtKB/TrEMBL
SMART EFh UniProtKB/TrEMBL
Superfamily-SCOP SSF47473 UniProtKB/TrEMBL
UniProt A0A2R9AJT3_PANPA UniProtKB/TrEMBL
  A0A2R9BIN3 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9BRE9_PANPA UniProtKB/TrEMBL