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Gene: SIGLEC1 (sialic acid binding Ig like lectin 1) Homo sapiens
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Symbol: SIGLEC1
Name: sialic acid binding Ig like lectin 1
RGD ID: 1323674
Description: Predicted to have virion binding activity. Predicted to be involved in clathrin-dependent endocytosis of virus by host cell; negative regulation of phagocytosis; and positive regulation of apoptotic process. Predicted to localize to cytoplasmic vesicle and plasma membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CD169; dJ1009E24.1; DKFZp667F058; FLJ00051; FLJ00055; FLJ00073; FLJ00411; FLJ32150; sialic acid binding Ig-like lectin 1, sialoadhesin; sialic acid-binding Ig-like lectin 1; sialic acid-binding immunoglobulin-like lectin 1; sialoadhesin; SIGLEC-1; SN
Orthologs:
Mus musculus (house mouse) : Siglec1 (sialic acid binding Ig-like lectin 1, sialoadhesin)  MGI  Alliance
Rattus norvegicus (Norway rat) : Siglec1 (sialic acid binding Ig like lectin 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Siglec1 (sialic acid binding Ig like lectin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SIGLEC1 (sialic acid binding Ig like lectin 1)
Canis lupus familiaris (dog) : SIGLEC1 (sialic acid binding Ig like lectin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Siglec1 (sialic acid binding Ig like lectin 1)
Sus scrofa (pig) : SIGLEC1 (sialic acid binding Ig like lectin 1)
Chlorocebus sabaeus (African green monkey) : SIGLEC1 (sialic acid binding Ig like lectin 1)
Heterocephalus glaber (naked mole-rat) : Siglec1 (sialic acid binding Ig like lectin 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl203,686,970 - 3,707,128 (-)EnsemblGRCh38hg38GRCh38
GRCh38203,686,970 - 3,712,600 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37203,667,617 - 3,693,213 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36203,615,617 - 3,635,775 (-)NCBINCBI36hg18NCBI36
Build 34203,617,206 - 3,635,775NCBI
Celera203,729,495 - 3,749,653 (-)NCBI
Cytogenetic Map20p13NCBI
HuRef203,615,947 - 3,636,103 (-)NCBIHuRef
CHM1_1203,667,931 - 3,688,082 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
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Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on SIGLEC1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1323674
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-09-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.