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Gene: BHLHE41 (basic helix-loop-helix family member e41) Homo sapiens
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Symbol: BHLHE41
Name: basic helix-loop-helix family member e41
Description: Exhibits several functions, including E-box binding activity; protein heterodimerization activity; and transcription corepressor activity. Involved in negative regulation of transcription by RNA polymerase II. Predicted to localize to the nuclear chromatin. Implicated in sleep disorder.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: basic helix-loop-helix domain containing, class B, 3; basic helix-loop-helix family, member e41; BHLHB3; class E basic helix-loop-helix protein 41; DEC2; differentially expressed in chondrocytes 2; differentially expressed in chondrocytes protein 2; enhancer-of-split and hairy-related protein 1; FNSS1; hDEC2; SHARP-1; SHARP1
Orthologs:
Mus musculus (house mouse) : Bhlhe41 (basic helix-loop-helix family, member e41)  MGI  Alliance
Rattus norvegicus (Norway rat) : Bhlhe41 (basic helix-loop-helix family, member e41)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Bhlhe41 (basic helix-loop-helix family member e41)
Pan paniscus (bonobo/pygmy chimpanzee) : BHLHE41 (basic helix-loop-helix family member e41)
Canis lupus familiaris (dog) : BHLHE41 (basic helix-loop-helix family member e41)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Bhlhe41 (basic helix-loop-helix family member e41)
Sus scrofa (pig) : BHLHE41 (basic helix-loop-helix family member e41)
Chlorocebus sabaeus (green monkey) : BHLHE41 (basic helix-loop-helix family member e41)
Heterocephalus glaber (naked mole-rat) : Bhlhe41 (basic helix-loop-helix family member e41)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl1226,120,030 - 26,125,037 (-)Ensembl
GRCh381226,120,030 - 26,125,037 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371226,272,959 - 26,278,003 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361226,164,226 - 26,169,113 (-)NCBINCBI36hg18NCBI36
Build 341226,164,227 - 26,169,113NCBI
Celera1231,419,506 - 31,424,550 (-)NCBI
Cytogenetic Map12p12.1NCBI
HuRef1226,043,295 - 26,047,960 (-)NCBIHuRef
CHM1_11226,237,976 - 26,243,020 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on BHLHE41
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 731061
Created: 2003-12-10
Species: Homo sapiens
Last Modified: 2020-02-04
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.