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Gene: ATF6 (activating transcription factor 6) Homo sapiens
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Symbol: ATF6
Name: activating transcription factor 6
Description: Exhibits several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; identical protein binding activity; and protein heterodimerization activity. Involved in several processes, including positive regulation of ATF6-mediated unfolded protein response; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress; and visual perception. Localizes to several cellular components, including Golgi apparatus; endoplasmic reticulum; and integral component of endoplasmic reticulum membrane. Implicated in achromatopsia 7.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ACHM7; activating transcription factor 6 alpha; ATF6-alpha; ATF6A; cAMP-dependent transcription factor ATF-6 alpha; cyclic AMP-dependent transcription factor ATF-6 alpha; DKFZp686P2194; FLJ21663
Orthologs:
Mus musculus (house mouse) : Atf6 (activating transcription factor 6)  MGI  Alliance
Rattus norvegicus (Norway rat) : Atf6 (activating transcription factor 6)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Atf6 (activating transcription factor 6)
Pan paniscus (bonobo/pygmy chimpanzee) : ATF6 (activating transcription factor 6)
Canis lupus familiaris (dog) : ATF6 (activating transcription factor 6)
Sus scrofa (pig) : ATF6 (activating transcription factor 6)
Chlorocebus sabaeus (African green monkey) : ATF6 (activating transcription factor 6)
Heterocephalus glaber (naked mole-rat) : Atf6 (activating transcription factor 6)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1161,766,320 - 161,964,070 (+)EnsemblGRCh38hg38GRCh38
GRCh381161,766,320 - 161,964,070 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371161,736,034 - 161,933,860 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361160,002,708 - 160,195,476 (+)NCBINCBI36hg18NCBI36
Build 341158,467,741 - 158,660,510NCBI
Celera1134,839,502 - 135,032,269 (+)NCBI
Cytogenetic Map1q23.3NCBI
HuRef1132,980,970 - 133,178,653 (+)NCBIHuRef
CHM1_11163,157,827 - 163,355,630 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on ATF6
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1313517
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-09-08
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.