IGSF11 (immunoglobulin superfamily member 11) - Rat Genome Database
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Gene: IGSF11 (immunoglobulin superfamily member 11) Homo sapiens
Analyze
Symbol: IGSF11
Name: immunoglobulin superfamily member 11
RGD ID: 1318715
Description: Exhibits ionotropic glutamate receptor binding activity. Involved in homophilic cell adhesion via plasma membrane adhesion molecules. Localizes to cell-cell junction.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: brain and testis-specific immunoglobin superfamily protein; brain and testis-specific immunoglobulin superfamily protein; BT-IgSF; cancer/testis antigen 119; CT119; CXADR like 1; CXADRL1; Igsf13; immunoglobulin superfamily, member 11; MGC35227; V-set and immunoglobulin domain containing 3; V-set and immunoglobulin domain-containing protein 3; VSIG3
Orthologs:
Mus musculus (house mouse) : Igsf11 (immunoglobulin superfamily, member 11)  MGI  Alliance
Rattus norvegicus (Norway rat) : Igsf11 (immunoglobulin superfamily, member 11)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Igsf11 (immunoglobulin superfamily member 11)
Pan paniscus (bonobo/pygmy chimpanzee) : IGSF11 (immunoglobulin superfamily member 11)
Canis lupus familiaris (dog) : IGSF11 (immunoglobulin superfamily member 11)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Igsf11 (immunoglobulin superfamily member 11)
Sus scrofa (pig) : IGSF11 (immunoglobulin superfamily member 11)
Chlorocebus sabaeus (African green monkey) : IGSF11 (immunoglobulin superfamily member 11)
Heterocephalus glaber (naked mole-rat) : Igsf11 (immunoglobulin superfamily member 11)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl3118,900,557 - 119,146,068 (-)EnsemblGRCh38hg38GRCh38
GRCh383118,900,557 - 119,146,064 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh373118,619,477 - 118,864,915 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363120,102,167 - 120,347,588 (-)NCBINCBI36hg18NCBI36
Build 343120,103,690 - 120,347,381NCBI
Celera3117,027,981 - 117,273,390 (-)NCBI
Cytogenetic Map3q13.32NCBI
HuRef3115,994,852 - 116,240,345 (-)NCBIHuRef
CHM1_13118,582,961 - 118,828,367 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

Additional References at PubMed
PMID:12207903   PMID:12477932   PMID:12851705   PMID:12975309   PMID:14702039   PMID:15795899   PMID:16108831   PMID:21982860   PMID:22952603   PMID:23251661   PMID:23376485   PMID:24023788  
PMID:25231870   PMID:26595655   PMID:30220083   PMID:32296183  


Genomics

Comparative Map Data
IGSF11
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl3118,900,557 - 119,146,068 (-)EnsemblGRCh38hg38GRCh38
GRCh383118,900,557 - 119,146,064 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh373118,619,477 - 118,864,915 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363120,102,167 - 120,347,588 (-)NCBINCBI36hg18NCBI36
Build 343120,103,690 - 120,347,381NCBI
Celera3117,027,981 - 117,273,390 (-)NCBI
Cytogenetic Map3q13.32NCBI
HuRef3115,994,852 - 116,240,345 (-)NCBIHuRef
CHM1_13118,582,961 - 118,828,367 (-)NCBICHM1_1
Igsf11
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391638,712,840 - 38,847,521 (+)NCBI
GRCm381638,892,476 - 39,027,159 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1638,892,671 - 39,027,159 (+)EnsemblGRCm38mm10GRCm38
MGSCv371638,902,458 - 39,027,272 (+)NCBIGRCm37mm9NCBIm37
MGSCv361638,821,677 - 38,946,491 (+)NCBImm8
Celera1639,299,325 - 39,427,101 (+)NCBICelera
Cytogenetic Map16B4NCBI
Igsf11
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01164,286,691 - 64,421,248 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1164,286,694 - 64,421,248 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01167,664,964 - 67,819,751 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41163,501,592 - 63,640,441 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11163,559,183 - 63,698,030 (-)NCBI
Celera1161,239,980 - 61,376,445 (-)NCBICelera
Cytogenetic Map11q21NCBI
Igsf11
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542718,696,888 - 18,716,896 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542718,698,774 - 18,716,669 (-)NCBIChiLan1.0ChiLan1.0
IGSF11
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.13122,946,368 - 123,143,485 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3122,948,246 - 122,972,742 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v03116,033,187 - 116,153,134 (-)NCBIMhudiblu_PPA_v0panPan3
IGSF11
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl3322,641,648 - 22,840,745 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.13322,641,370 - 22,825,973 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Igsf11
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049365365,947,915 - 6,090,004 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IGSF11
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13141,093,021 - 141,289,504 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113141,148,489 - 141,289,504 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213150,586,617 - 150,616,187 (+)NCBISscrofa10.2Sscrofa10.2susScr3
IGSF11
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1 Ensembl2261,797,938 - 61,916,787 (+)Ensembl
ChlSab1.12261,708,162 - 61,916,802 (+)NCBI
Igsf11
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473129,109,803 - 29,272,322 (+)NCBI

Position Markers
D3S3664  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh373118,674,007 - 118,674,254UniSTSGRCh37
Build 363120,156,697 - 120,156,944RGDNCBI36
Celera3117,082,509 - 117,082,756RGD
Cytogenetic Map3q13.32UniSTS
HuRef3116,049,406 - 116,049,653UniSTS
Marshfield Genetic Map3138.0RGD
Marshfield Genetic Map3138.0UniSTS
Genethon Genetic Map3140.0UniSTS
deCODE Assembly Map3126.59UniSTS
Whitehead-YAC Contig Map3 UniSTS
G20594  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh373118,619,545 - 118,619,746UniSTSGRCh37
Build 363120,102,235 - 120,102,436RGDNCBI36
Celera3117,028,049 - 117,028,250RGD
Cytogenetic Map3q13.32UniSTS
HuRef3115,994,920 - 115,995,121UniSTS
A005Y20  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh373118,619,545 - 118,619,746UniSTSGRCh37
Build 363120,102,235 - 120,102,436RGDNCBI36
Celera3117,028,049 - 117,028,250RGD
Cytogenetic Map3q13.32UniSTS
HuRef3115,994,920 - 115,995,121UniSTS
GeneMap99-GB4 RH Map3418.82UniSTS
RH94162  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh373118,666,007 - 118,666,176UniSTSGRCh37
Build 363120,148,697 - 120,148,866RGDNCBI36
Celera3117,074,510 - 117,074,679RGD
Cytogenetic Map3q13.32UniSTS
HuRef3116,041,407 - 116,041,576UniSTS
GeneMap99-GB4 RH Map3421.43UniSTS
NIB1484  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh373118,619,552 - 118,619,722UniSTSGRCh37
Build 363120,102,242 - 120,102,412RGDNCBI36
Celera3117,028,056 - 117,028,226RGD
Cytogenetic Map3q13.32UniSTS
HuRef3115,994,927 - 115,995,097UniSTS
GeneMap99-GB4 RH Map3418.82UniSTS
Whitehead-RH Map3529.0UniSTS
REN40251  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371454,331,481 - 54,331,729UniSTSGRCh37
GRCh373118,719,218 - 118,719,469UniSTSGRCh37
Build 363120,201,908 - 120,202,159RGDNCBI36
Celera1434,381,189 - 34,381,437UniSTS
Celera3117,127,719 - 117,127,970RGD
Cytogenetic Map3q13.32UniSTS
HuRef1434,494,604 - 34,494,852UniSTS
HuRef3116,094,620 - 116,094,871UniSTS
REN90194  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh373118,849,204 - 118,849,454UniSTSGRCh37
GRCh37X153,899,221 - 153,899,472UniSTSGRCh37
Build 36X153,552,415 - 153,552,666RGDNCBI36
CeleraX154,057,302 - 154,057,553RGD
Celera3117,257,698 - 117,257,948UniSTS
Cytogenetic Map3q13.32UniSTS
HuRef3116,224,656 - 116,224,906UniSTS
HuRefX142,443,337 - 142,443,588UniSTS

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:3819
Count of miRNA genes:875
Interacting mature miRNAs:1016
Transcripts:ENST00000354673, ENST00000393775, ENST00000425327, ENST00000441144, ENST00000459718, ENST00000480431, ENST00000483401, ENST00000489689, ENST00000491903, ENST00000494802
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component
High
Medium 76 58 2 8 2 633 44 1479 8 526 34 567
Low 1768 1006 819 120 167 21 2478 1794 2156 233 547 499 104 1 245 1625 2
Below cutoff 471 1790 672 331 1091 271 1222 343 60 140 331 1016 65 946 595 2

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001015887 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001353318 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001353319 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001353320 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001353321 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001353322 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001353323 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001353324 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001353325 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001353326 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_152538 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011512463 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011512464 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011512465 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011512466 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011512469 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011512471 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011512474 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017005789 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_024453376 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_024453377 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AA292896 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB071618 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB079879 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC007023 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC012032 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC068984 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC083800 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK097667 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK122611 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK292387 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK296503 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL834256 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY358141 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC034411 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BI828564 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471052 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CQ789642 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HF584358 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000354673   ⟹   ENSP00000346700
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl3118,900,636 - 119,105,221 (-)Ensembl
RefSeq Acc Id: ENST00000393775   ⟹   ENSP00000377370
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl3118,900,557 - 119,034,846 (-)Ensembl
RefSeq Acc Id: ENST00000425327   ⟹   ENSP00000406092
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl3118,900,557 - 119,146,068 (-)Ensembl
RefSeq Acc Id: ENST00000441144   ⟹   ENSP00000401240
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl3118,902,154 - 119,146,035 (-)Ensembl
RefSeq Acc Id: ENST00000459718
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl3118,925,923 - 118,930,253 (-)Ensembl
RefSeq Acc Id: ENST00000480431   ⟹   ENSP00000418047
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl3118,928,658 - 119,034,955 (-)Ensembl
RefSeq Acc Id: ENST00000483401   ⟹   ENSP00000418976
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl3118,928,578 - 119,013,237 (-)Ensembl
RefSeq Acc Id: ENST00000489689   ⟹   ENSP00000420486
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl3118,900,634 - 119,034,792 (-)Ensembl
RefSeq Acc Id: ENST00000491903   ⟹   ENSP00000417413
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl3118,902,391 - 119,034,728 (-)Ensembl
RefSeq Acc Id: ENST00000494802
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl3118,948,320 - 119,145,993 (-)Ensembl
RefSeq Acc Id: NM_001015887   ⟹   NP_001015887
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh383118,900,557 - 119,034,846 (-)NCBI
GRCh373118,619,477 - 118,864,915 (-)NCBI
Build 363120,102,167 - 120,236,366 (-)NCBI Archive
Celera3117,027,981 - 117,273,390 (-)RGD
HuRef3115,994,852 - 116,240,345 (-)ENTREZGENE
CHM1_13118,582,961 - 118,717,177 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001353318   ⟹   NP_001340247
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh383118,900,557 - 119,034,846 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001353319   ⟹   NP_001340248
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh383118,900,557 - 119,034,846 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001353320   ⟹   NP_001340249
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh383118,900,557 - 119,146,020 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001353321   ⟹   NP_001340250
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh383118,900,557 - 119,034,846 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001353322   ⟹   NP_001340251
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh383118,900,557 - 119,146,020 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001353323   ⟹   NP_001340252
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh383118,900,557 - 119,034,846 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001353324   ⟹   NP_001340253
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh383118,900,557 - 119,034,846 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001353325   ⟹   NP_001340254
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh383118,900,557 - 119,034,846 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001353326   ⟹   NP_001340255
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh383118,900,557 - 119,034,846 (-)NCBI
Sequence:
RefSeq Acc Id: NM_152538   ⟹   NP_689751
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh383118,900,557 - 119,146,020 (-)NCBI
GRCh373118,619,477 - 118,864,915 (-)NCBI
Build 363120,102,167 - 120,347,588 (-)NCBI Archive
Celera3117,027,981 - 117,273,390 (-)RGD
HuRef3115,994,852 - 116,240,345 (-)ENTREZGENE
CHM1_13118,582,961 - 118,828,367 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011512463   ⟹   XP_011510765
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh383118,900,630 - 119,112,714 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011512464   ⟹   XP_011510766
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh383118,900,630 - 119,112,678 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011512465   ⟹   XP_011510767
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh383118,900,630 - 119,146,064 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011512466   ⟹   XP_011510768
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh383118,900,630 - 119,034,892 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011512469   ⟹   XP_011510771
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh383118,900,630 - 119,112,714 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011512471   ⟹   XP_011510773
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh383118,900,630 - 119,034,893 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011512474   ⟹   XP_011510776
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh383118,902,801 - 119,034,902 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017005789   ⟹   XP_016861278
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh383118,900,630 - 118,942,811 (-)NCBI
Sequence:
RefSeq Acc Id: XM_024453376   ⟹   XP_024309144
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh383118,900,630 - 118,983,445 (-)NCBI
Sequence:
RefSeq Acc Id: XM_024453377   ⟹   XP_024309145
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh383118,902,874 - 119,034,673 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001015887 (Get FASTA)   NCBI Sequence Viewer  
  NP_001340247 (Get FASTA)   NCBI Sequence Viewer  
  NP_001340248 (Get FASTA)   NCBI Sequence Viewer  
  NP_001340249 (Get FASTA)   NCBI Sequence Viewer  
  NP_001340250 (Get FASTA)   NCBI Sequence Viewer  
  NP_001340251 (Get FASTA)   NCBI Sequence Viewer  
  NP_001340252 (Get FASTA)   NCBI Sequence Viewer  
  NP_001340253 (Get FASTA)   NCBI Sequence Viewer  
  NP_001340254 (Get FASTA)   NCBI Sequence Viewer  
  NP_001340255 (Get FASTA)   NCBI Sequence Viewer  
  NP_689751 (Get FASTA)   NCBI Sequence Viewer  
  XP_011510765 (Get FASTA)   NCBI Sequence Viewer  
  XP_011510766 (Get FASTA)   NCBI Sequence Viewer  
  XP_011510767 (Get FASTA)   NCBI Sequence Viewer  
  XP_011510768 (Get FASTA)   NCBI Sequence Viewer  
  XP_011510771 (Get FASTA)   NCBI Sequence Viewer  
  XP_011510773 (Get FASTA)   NCBI Sequence Viewer  
  XP_011510776 (Get FASTA)   NCBI Sequence Viewer  
  XP_016861278 (Get FASTA)   NCBI Sequence Viewer  
  XP_024309144 (Get FASTA)   NCBI Sequence Viewer  
  XP_024309145 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH34411 (Get FASTA)   NCBI Sequence Viewer  
  AAQ88508 (Get FASTA)   NCBI Sequence Viewer  
  BAC05139 (Get FASTA)   NCBI Sequence Viewer  
  BAC07546 (Get FASTA)   NCBI Sequence Viewer  
  BAD90695 (Get FASTA)   NCBI Sequence Viewer  
  BAF85076 (Get FASTA)   NCBI Sequence Viewer  
  BAG53622 (Get FASTA)   NCBI Sequence Viewer  
  BAG59136 (Get FASTA)   NCBI Sequence Viewer  
  CAD38931 (Get FASTA)   NCBI Sequence Viewer  
  CAG24381 (Get FASTA)   NCBI Sequence Viewer  
  CCQ43855 (Get FASTA)   NCBI Sequence Viewer  
  EAW79579 (Get FASTA)   NCBI Sequence Viewer  
  EAW79580 (Get FASTA)   NCBI Sequence Viewer  
  Q5DX21 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_689751   ⟸   NM_152538
- Peptide Label: isoform a precursor
- UniProtKB: Q5DX21 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001015887   ⟸   NM_001015887
- Peptide Label: isoform b precursor
- UniProtKB: Q5DX21 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_011510767   ⟸   XM_011512465
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_011510771   ⟸   XM_011512469
- Peptide Label: isoform X4
- UniProtKB: Q5DX21 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_011510765   ⟸   XM_011512463
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_011510766   ⟸   XM_011512464
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_011510773   ⟸   XM_011512471
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_011510768   ⟸   XM_011512466
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_011510776   ⟸   XM_011512474
- Peptide Label: isoform X8
- Sequence:
RefSeq Acc Id: XP_016861278   ⟸   XM_017005789
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: NP_001340249   ⟸   NM_001353320
- Peptide Label: isoform a precursor
- Sequence:
RefSeq Acc Id: NP_001340251   ⟸   NM_001353322
- Peptide Label: isoform f precursor
- Sequence:
RefSeq Acc Id: NP_001340253   ⟸   NM_001353324
- Peptide Label: isoform h precursor
- Sequence:
RefSeq Acc Id: NP_001340250   ⟸   NM_001353321
- Peptide Label: isoform e precursor
- Sequence:
RefSeq Acc Id: NP_001340252   ⟸   NM_001353323
- Peptide Label: isoform g precursor
- Sequence:
RefSeq Acc Id: NP_001340255   ⟸   NM_001353326
- Peptide Label: isoform j
- Sequence:
RefSeq Acc Id: NP_001340254   ⟸   NM_001353325
- Peptide Label: isoform i
- Sequence:
RefSeq Acc Id: NP_001340248   ⟸   NM_001353319
- Peptide Label: isoform d
- Sequence:
RefSeq Acc Id: NP_001340247   ⟸   NM_001353318
- Peptide Label: isoform c
- Sequence:
RefSeq Acc Id: XP_024309144   ⟸   XM_024453376
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_024309145   ⟸   XM_024453377
- Peptide Label: isoform X7
- Sequence:
RefSeq Acc Id: ENSP00000406092   ⟸   ENST00000425327
RefSeq Acc Id: ENSP00000417413   ⟸   ENST00000491903
RefSeq Acc Id: ENSP00000401240   ⟸   ENST00000441144
RefSeq Acc Id: ENSP00000418047   ⟸   ENST00000480431
RefSeq Acc Id: ENSP00000418976   ⟸   ENST00000483401
RefSeq Acc Id: ENSP00000377370   ⟸   ENST00000393775
RefSeq Acc Id: ENSP00000346700   ⟸   ENST00000354673
RefSeq Acc Id: ENSP00000420486   ⟸   ENST00000489689
Protein Domains
Ig-like   Ig-like C2-type   Ig-like V-type   IGv

Promoters
RGD ID:6865322
Promoter ID:EPDNEW_H5826
Type:initiation region
Name:IGSF11_1
Description:immunoglobulin superfamily member 11
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh383119,034,792 - 119,034,852EPDNEW
RGD ID:6801149
Promoter ID:HG_KWN:45906
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   Lymphoblastoid
Transcripts:NM_001015887,   UC003EBX.1
Position:
Human AssemblyChrPosition (strand)Source
Build 363120,236,224 - 120,236,724 (-)MPROMDB

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 3q11.1-21.1(chr3:93886671-123216683)x1 copy number loss See cases [RCV000051543] Chr3:93886671..123216683 [GRCh38]
Chr3:93605515..122935530 [GRCh37]
Chr3:95088205..124418220 [NCBI36]
Chr3:3q11.1-21.1
pathogenic
GRCh38/hg38 3q13.32-21.2(chr3:119117166-125920734)x1 copy number loss See cases [RCV000051546] Chr3:119117166..125920734 [GRCh38]
Chr3:118836013..125639577 [GRCh37]
Chr3:120318703..127122267 [NCBI36]
Chr3:3q13.32-21.2
pathogenic
NM_001015887.1(IGSF11):c.424+1005G>A single nucleotide variant Lung cancer [RCV000092836] Chr3:118927504 [GRCh38]
Chr3:118646351 [GRCh37]
Chr3:3q13.32
uncertain significance
NM_001015887.1(IGSF11):c.52+48863A>T single nucleotide variant Lung cancer [RCV000092837] Chr3:118985668 [GRCh38]
Chr3:118704515 [GRCh37]
Chr3:3q13.32
uncertain significance
NM_152538.2(IGSF11):c.-142-13462G>T single nucleotide variant Lung cancer [RCV000092838] Chr3:119126240 [GRCh38]
Chr3:118845087 [GRCh37]
Chr3:3q13.32
uncertain significance
GRCh38/hg38 3q13.32(chr3:119033541-119081373)x4 copy number gain See cases [RCV000134263] Chr3:119033541..119081373 [GRCh38]
Chr3:118752388..118800220 [GRCh37]
Chr3:120235078..120282910 [NCBI36]
Chr3:3q13.32
benign|likely benign|conflicting data from submitters
GRCh38/hg38 3q13.11-29(chr3:103426882-198110178)x3 copy number gain See cases [RCV000134948] Chr3:103426882..198110178 [GRCh38]
Chr3:103145726..197837049 [GRCh37]
Chr3:104628416..199321446 [NCBI36]
Chr3:3q13.11-29
pathogenic
GRCh38/hg38 3q13.32-13.33(chr3:117844958-120797026)x4 copy number gain See cases [RCV000135591] Chr3:117844958..120797026 [GRCh38]
Chr3:117563805..120515873 [GRCh37]
Chr3:119046495..121998563 [NCBI36]
Chr3:3q13.32-13.33
uncertain significance
GRCh38/hg38 3q13.31-21.1(chr3:115019074-122513398)x1 copy number loss See cases [RCV000135961] Chr3:115019074..122513398 [GRCh38]
Chr3:114737921..122232245 [GRCh37]
Chr3:116220611..123714935 [NCBI36]
Chr3:3q13.31-21.1
pathogenic
GRCh38/hg38 3q13.31-13.32(chr3:116366433-119033600)x3 copy number gain See cases [RCV000138196] Chr3:116366433..119033600 [GRCh38]
Chr3:116085280..118752447 [GRCh37]
Chr3:117567970..120235137 [NCBI36]
Chr3:3q13.31-13.32
uncertain significance
GRCh38/hg38 3q13.2-21.3(chr3:112620977-128734134)x1 copy number loss See cases [RCV000139033] Chr3:112620977..128734134 [GRCh38]
Chr3:112339824..128452977 [GRCh37]
Chr3:113822514..129935667 [NCBI36]
Chr3:3q13.2-21.3
pathogenic
GRCh38/hg38 3q13.32(chr3:119059834-119081373)x4 copy number gain See cases [RCV000141024] Chr3:119059834..119081373 [GRCh38]
Chr3:118778681..118800220 [GRCh37]
Chr3:120261371..120282910 [NCBI36]
Chr3:3q13.32
benign|likely benign|conflicting data from submitters
GRCh38/hg38 3q13.31-21.2(chr3:114122562-124532374)x1 copy number loss See cases [RCV000142009] Chr3:114122562..124532374 [GRCh38]
Chr3:113841409..124251221 [GRCh37]
Chr3:115324099..125733911 [NCBI36]
Chr3:3q13.31-21.2
pathogenic
GRCh38/hg38 3q11.1-24(chr3:93800620-145695381)x3 copy number gain See cases [RCV000142340] Chr3:93800620..145695381 [GRCh38]
Chr3:93519464..145413168 [GRCh37]
Chr3:95002154..146895858 [NCBI36]
Chr3:3q11.1-24
pathogenic
GRCh38/hg38 3q13.32(chr3:119016439-119098881)x3 copy number gain See cases [RCV000142846] Chr3:119016439..119098881 [GRCh38]
Chr3:118735286..118817728 [GRCh37]
Chr3:120217976..120300418 [NCBI36]
Chr3:3q13.32
likely benign
GRCh38/hg38 3q13.32-13.33(chr3:117844958-120826621)x4 copy number gain See cases [RCV000142877] Chr3:117844958..120826621 [GRCh38]
Chr3:117563805..120545468 [GRCh37]
Chr3:119046495..122028158 [NCBI36]
Chr3:3q13.32-13.33
uncertain significance
GRCh38/hg38 3q13.2-13.33(chr3:112520553-120031022)x1 copy number loss See cases [RCV000142725] Chr3:112520553..120031022 [GRCh38]
Chr3:112239400..119749869 [GRCh37]
Chr3:113722090..121232559 [NCBI36]
Chr3:3q13.2-13.33
pathogenic
GRCh38/hg38 3q13.32-21.3(chr3:118673898-126540730)x1 copy number loss See cases [RCV000143695] Chr3:118673898..126540730 [GRCh38]
Chr3:118392745..126259573 [GRCh37]
Chr3:119875435..127742263 [NCBI36]
Chr3:3q13.32-21.3
pathogenic
GRCh37/hg19 3p26.3-q29(chr3:61892-197851986)x3 copy number gain See cases [RCV000511055] Chr3:61892..197851986 [GRCh37]
Chr3:3p26.3-q29
pathogenic
GRCh37/hg19 3p26.3-q29(chr3:61892-197851986) copy number gain See cases [RCV000512358] Chr3:61892..197851986 [GRCh37]
Chr3:3p26.3-q29
pathogenic
GRCh37/hg19 3q13.31-21.1(chr3:115518341-122129283)x1 copy number loss not provided [RCV000682298] Chr3:115518341..122129283 [GRCh37]
Chr3:3q13.31-21.1
pathogenic
GRCh37/hg19 3p26.3-q29(chr3:61495-197838262)x3 copy number gain not provided [RCV000742138] Chr3:61495..197838262 [GRCh37]
Chr3:3p26.3-q29
pathogenic
GRCh37/hg19 3p26.3-q29(chr3:60174-197948027)x3 copy number gain not provided [RCV000742133] Chr3:60174..197948027 [GRCh37]
Chr3:3p26.3-q29
pathogenic
GRCh37/hg19 3q13.32(chr3:118730933-118812889)x3 copy number gain not provided [RCV000742710] Chr3:118730933..118812889 [GRCh37]
Chr3:3q13.32
benign
GRCh37/hg19 3q13.32(chr3:118731305-118824418)x3 copy number gain not provided [RCV000742711] Chr3:118731305..118824418 [GRCh37]
Chr3:3q13.32
benign
GRCh37/hg19 3q13.32(chr3:118733449-118963249)x4 copy number gain not provided [RCV001259227] Chr3:118733449..118963249 [GRCh37]
Chr3:3q13.32
uncertain significance

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:16669 AgrOrtholog
COSMIC IGSF11 COSMIC
Ensembl Genes ENSG00000144847 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSP00000346700 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000377370 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000401240 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000406092 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000417413 ENTREZGENE, UniProtKB/TrEMBL
  ENSP00000418047 UniProtKB/TrEMBL
  ENSP00000418976 UniProtKB/TrEMBL
  ENSP00000420486 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENST00000354673 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000393775 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000425327 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000441144 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000480431 UniProtKB/TrEMBL
  ENST00000483401 UniProtKB/TrEMBL
  ENST00000489689 ENTREZGENE, UniProtKB/TrEMBL
  ENST00000491903 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000144847 GTEx
HGNC ID HGNC:16669 ENTREZGENE
Human Proteome Map IGSF11 Human Proteome Map
InterPro Ig-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_sub UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_sub2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_V-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IGSF11 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:152404 UniProtKB/Swiss-Prot
NCBI Gene 152404 ENTREZGENE
OMIM 608351 OMIM
PANTHER PTHR44699 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam V-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA134939253 PharmGKB
PROSITE IG_LIKE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART IGc2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00409 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniGene Hs.112873 ENTREZGENE
UniProt C9IZX3_HUMAN UniProtKB/TrEMBL
  C9JAD3_HUMAN UniProtKB/TrEMBL
  C9JBA5_HUMAN UniProtKB/TrEMBL
  C9JMW0_HUMAN UniProtKB/TrEMBL
  IGS11_HUMAN UniProtKB/Swiss-Prot
  L8E968_HUMAN UniProtKB/TrEMBL
  Q5DX21 ENTREZGENE
UniProt Secondary C9JZN0 UniProtKB/Swiss-Prot
  Q8N4F1 UniProtKB/Swiss-Prot
  Q8N7T8 UniProtKB/Swiss-Prot
  Q8NDD2 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-11-24 IGSF11  immunoglobulin superfamily member 11  IGSF11  immunoglobulin superfamily, member 11  Symbol and/or name change 5135510 APPROVED
2015-11-24 IGSF11  immunoglobulin superfamily member 11    immunoglobulin superfamily, member 11  Symbol and/or name change 5135510 APPROVED
2011-09-01 IGSF11  immunoglobulin superfamily, member 11  IGSF11  immunoglobulin superfamily, member 11  Symbol and/or name change 5135510 APPROVED