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Gene: PDE4D (phosphodiesterase 4D) Homo sapiens
Symbol: PDE4D
Name: phosphodiesterase 4D
RGD ID: 736102
Description: Exhibits several functions, including 3',5'-cyclic-AMP phosphodiesterase activity; cAMP binding activity; and enzyme binding activity. Involved in several processes, including cAMP catabolic process; cellular response to organonitrogen compound; and positive regulation of cytokine production. Localizes to calcium channel complex; cytosol; and plasma membrane. Implicated in acrodysostosis.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ACRDYS2; cAMP-specific 3',5'-cyclic phosphodiesterase 4D; cAMP-specific phosphodiesterase 4D; cAMP-specific phosphodiesterase PDE4D6; DKFZp686M11213; DPDE3; dunce-like phosphodiesterase E3; FLJ97311; HSPDE4D; PDE43; PDE4DN2; phosphodiesterase 4D, cAMP-specific (dunce; phosphodiesterase 4D, cAMP-specific (phosphodiesterase E3 dunce homolog, Drosophila); phosphodiesterase E3 dunce homolog; STRK1; testicular tissue protein Li 136
Mus musculus (house mouse) : Pde4d (phosphodiesterase 4D, cAMP specific)  MGI  Alliance
Rattus norvegicus (Norway rat) : Pde4d (phosphodiesterase 4D)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pde4d (phosphodiesterase 4D)
Pan paniscus (bonobo/pygmy chimpanzee) : PDE4D (phosphodiesterase 4D)
Canis lupus familiaris (dog) : PDE4D (phosphodiesterase 4D)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pde4d (phosphodiesterase 4D)
Sus scrofa (pig) : PDE4D (phosphodiesterase 4D)
Chlorocebus sabaeus (African green monkey) : PDE4D (phosphodiesterase 4D)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl558,969,038 - 60,522,120 (-)EnsemblGRCh38hg38GRCh38
GRCh38558,969,038 - 60,524,329 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37558,264,865 - 59,783,925 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36558,300,622 - 59,225,378 (-)NCBINCBI36hg18NCBI36
Build 34558,302,467 - 58,918,032NCBI
Celera555,205,298 - 56,725,032 (-)NCBI
Cytogenetic Map5q11.2-q12.1NCBI
HuRef555,222,770 - 56,741,723 (-)ENTREZGENEHuRef
CHM1_1558,265,111 - 59,783,530 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
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References - uncurated


Comparative Map Data
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RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants