INSR (insulin receptor) - Rat Genome Database

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Gene: INSR (insulin receptor) Homo sapiens
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Symbol: INSR
Name: insulin receptor
RGD ID: 69029
HGNC Page HGNC
Description: Enables several functions, including insulin-like growth factor binding activity; peptide binding activity; and purine ribonucleoside triphosphate binding activity. Involved in several processes, including positive regulation of intracellular signal transduction; positive regulation of nitrogen compound metabolic process; and protein phosphorylation. Located in caveola. Is integral component of plasma membrane. Part of insulin receptor complex. Colocalizes with nuclear envelope and nuclear lumen. Implicated in Donohue syndrome; diabetes (multiple); familial hyperinsulinemic hypoglycemia 5; and reproductive organ cancer (multiple). Biomarker of Alzheimer's disease; breast cancer; hepatocellular carcinoma; renal cell carcinoma; and seminoma.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: CD220; HHF5; IR
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38197,112,265 - 7,294,414 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl197,112,255 - 7,294,414 (-)EnsemblGRCh38hg38GRCh38
GRCh37197,112,276 - 7,294,425 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36197,063,266 - 7,245,011 (-)NCBINCBI36hg18NCBI36
Build 34197,067,637 - 7,245,011NCBI
Celera197,049,684 - 7,205,258 (-)NCBI
Cytogenetic Map19p13.2NCBI
HuRef196,846,024 - 7,028,322 (-)NCBIHuRef
CHM1_1197,111,894 - 7,294,424 (-)NCBICHM1_1
T2T-CHM13v2.0197,103,362 - 7,286,608 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model