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Gene: PCSK1N (proprotein convertase subtilisin/kexin type 1 inhibitor) Homo sapiens
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Symbol: PCSK1N
Name: proprotein convertase subtilisin/kexin type 1 inhibitor
Description: Predicted to have endopeptidase inhibitor activity. Predicted to be involved in several processes, including negative regulation of endopeptidase activity; peptide hormone processing; and response to dietary excess. Predicted to localize to the extracellular space. Biomarker of Alzheimer's disease and dementia.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: BigLEN; granin-like neuroendocrine peptide; PEN; pro-SAAS; proprotein convertase 1 inhibitor; proSAAS; SAAS; SCG8; SgVIII
Orthologs:
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 EnsemblX48,831,096 - 48,835,610 (-)Ensembl
GRCh38X48,831,096 - 48,835,610 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X48,689,504 - 48,694,036 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X48,574,450 - 48,578,904 (-)NCBINCBI36hg18NCBI36
Build 34X48,445,755 - 48,450,209NCBI
CeleraX52,969,569 - 52,974,023 (+)NCBI
Cytogenetic MapXp11.23NCBI
HuRefX46,349,219 - 46,353,523 (-)NCBIHuRef
CHM1_1X48,720,644 - 48,725,174 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on PCSK1N
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 737617
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.