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Gene: GFAP (glial fibrillary acidic protein) Homo sapiens
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Symbol: GFAP
Name: glial fibrillary acidic protein
Description: Exhibits identical protein binding activity. Involved in intermediate filament organization. Localizes to the cytoplasm and intermediate filament cytoskeleton. Predicted to colocalize with the lysosome. Implicated in Alexander disease.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ALXDRD; FLJ42474; FLJ45472
Orthologs:
Mus musculus (house mouse) : Gfap (glial fibrillary acidic protein)  MGI  Alliance
Rattus norvegicus (Norway rat) : Gfap (glial fibrillary acidic protein)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gfap (glial fibrillary acidic protein)
Pan paniscus (bonobo/pygmy chimpanzee) : GFAP (glial fibrillary acidic protein)
Canis lupus familiaris (dog) : GFAP (glial fibrillary acidic protein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gfap (glial fibrillary acidic protein)
Sus scrofa (pig) : GFAP (glial fibrillary acidic protein)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381744,903,159 - 44,915,552 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371742,982,994 - 42,992,920 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361740,338,519 - 40,348,394 (-)NCBINCBI36hg18NCBI36
Build 341740,338,518 - 40,348,394NCBI
Celera1739,693,499 - 39,703,421 (-)NCBI
Cytogenetic Map17q21.31NCBI
HuRef1738,748,049 - 38,758,000 (-)NCBIHuRef
CHM1_11743,219,135 - 43,229,061 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on GFAP
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 619574
Created: 2002-07-23
Species: Homo sapiens
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.