Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: GFAP (glial fibrillary acidic protein) Homo sapiens
Analyze
Symbol: GFAP
Name: glial fibrillary acidic protein
RGD ID: 619574
Description: Exhibits identical protein binding activity. Involved in intermediate filament organization. Localizes to cytoplasm and intermediate filament cytoskeleton. Predicted to colocalize with lysosome. Implicated in Alexander disease.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ALXDRD; FLJ42474; FLJ45472
Orthologs:
Mus musculus (house mouse) : Gfap (glial fibrillary acidic protein)  MGI  Alliance
Rattus norvegicus (Norway rat) : Gfap (glial fibrillary acidic protein)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gfap (glial fibrillary acidic protein)
Pan paniscus (bonobo/pygmy chimpanzee) : GFAP (glial fibrillary acidic protein)
Canis lupus familiaris (dog) : GFAP (glial fibrillary acidic protein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gfap (glial fibrillary acidic protein)
Sus scrofa (pig) : GFAP (glial fibrillary acidic protein)
Chlorocebus sabaeus (African green monkey) : GFAP (glial fibrillary acidic protein)
Heterocephalus glaber (naked mole-rat) : Gfap (glial fibrillary acidic protein)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1744,903,159 - 44,916,937 (-)EnsemblGRCh38hg38GRCh38
GRCh381744,903,159 - 44,915,552 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371742,982,994 - 42,992,920 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361740,338,519 - 40,348,394 (-)NCBINCBI36hg18NCBI36
Build 341740,338,518 - 40,348,394NCBI
Celera1739,693,499 - 39,703,421 (-)NCBI
Cytogenetic Map17q21.31NCBI
HuRef1738,748,049 - 38,758,000 (-)NCBIHuRef
CHM1_11743,219,135 - 43,229,061 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on GFAP
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 619574
Created: 2002-07-23
Species: Homo sapiens
Last Modified: 2020-11-10
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.