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Gene: F13A1 (coagulation factor XIII A chain) Homo sapiens
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Symbol: F13A1
Name: coagulation factor XIII A chain
Description: Exhibits protein-glutamine gamma-glutamyltransferase activity. Involved in blood coagulation, fibrin clot formation and peptide cross-linking. Localizes to the blood microparticle and collagen-containing extracellular matrix. Implicated in artery disease (multiple); factor XIII deficiency; priapism; and thrombophilia (multiple). Biomarker of Crohn's disease; diabetic retinopathy; and precursor B lymphoblastic lymphoma/leukemia.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: bA525O21.1 (coagulation factor XIII, A1 polypeptide); coagulation factor XIII, A polypeptide; coagulation factor XIII, A1 polypeptide; coagulation factor XIIIa; F13A; factor XIIIa; fibrin stabilizing factor, A subunit; fibrinoligase; FSF, A subunit; protein-glutamine gamma-glutamyltransferase A chain; TGase; transglutaminase A chain; transglutaminase. plasma
Orthologs:
Mus musculus (house mouse) : F13a1 (coagulation factor XIII, A1 subunit)  MGI  Alliance
Rattus norvegicus (Norway rat) : F13a1 (coagulation factor XIII A1 chain)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : F13a1 (coagulation factor XIII A chain)
Pan paniscus (bonobo/pygmy chimpanzee) : F13A1 (coagulation factor XIII A chain)
Canis lupus familiaris (dog) : F13A1 (coagulation factor XIII A chain)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : F13a1 (coagulation factor XIII A chain)
Sus scrofa (pig) : F13A1 (coagulation factor XIII A chain)
more info ...
Allele / Splice: See ClinVar data
Is Marker For: QTLs:   PRSTS5_H  
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3866,144,084 - 6,320,662 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3766,144,311 - 6,320,924 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3666,089,310 - 6,265,923 (-)NCBINCBI36hg18NCBI36
Build 3466,089,316 - 6,265,901NCBI
Celera67,372,733 - 7,550,578 (-)NCBI
Cytogenetic Map6p25.1NCBI
HuRef66,020,217 - 6,197,010 (-)NCBIHuRef
CHM1_166,146,854 - 6,323,031 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on F13A1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 732286
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.