Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: F13A1 (coagulation factor XIII A chain) Homo sapiens
Symbol: F13A1
Name: coagulation factor XIII A chain
Description: Exhibits protein-glutamine gamma-glutamyltransferase activity. Involved in blood coagulation, fibrin clot formation and peptide cross-linking. Localizes to the blood microparticle and collagen-containing extracellular matrix. Implicated in artery disease (multiple); factor XIII deficiency; priapism; and thrombophilia (multiple). Biomarker of Crohn's disease; diabetic retinopathy; and precursor B lymphoblastic lymphoma/leukemia.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: bA525O21.1 (coagulation factor XIII, A1 polypeptide); coagulation factor XIII, A polypeptide; coagulation factor XIII, A1 polypeptide; coagulation factor XIIIa; F13A; factor XIIIa; fibrin stabilizing factor, A subunit; fibrinoligase; FSF, A subunit; protein-glutamine gamma-glutamyltransferase A chain; TGase; transglutaminase A chain; transglutaminase. plasma
Mus musculus (house mouse) : F13a1 (coagulation factor XIII, A1 subunit)  MGI  Alliance
Rattus norvegicus (Norway rat) : F13a1 (coagulation factor XIII A1 chain)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : F13a1 (coagulation factor XIII A chain)
Pan paniscus (bonobo/pygmy chimpanzee) : F13A1 (coagulation factor XIII A chain)
Canis lupus familiaris (dog) : F13A1 (coagulation factor XIII A chain)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : F13a1 (coagulation factor XIII A chain)
Sus scrofa (pig) : F13A1 (coagulation factor XIII A chain)
more info ...
Allele / Splice: See ClinVar data
Is Marker For: QTLs:   PRSTS5_H  
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh3866,144,084 - 6,320,662 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3766,144,311 - 6,320,924 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3666,089,310 - 6,265,923 (-)NCBINCBI36hg18NCBI36
Build 3466,089,316 - 6,265,901NCBI
Celera67,372,733 - 7,550,578 (-)NCBI
Cytogenetic Map6p25.1NCBI
HuRef66,020,217 - 6,197,010 (-)NCBIHuRef
CHM1_166,146,854 - 6,323,031 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on F13A1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 732286
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-10-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.