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Gene: SYT4 (synaptotagmin 4) Homo sapiens
Symbol: SYT4
Name: synaptotagmin 4
Description: Predicted to have several functions, including SNARE binding activity; calcium ion binding activity; and phospholipid binding activity. Involved in negative regulation of catecholamine secretion and positive regulation of dendrite extension. Localizes to intracellular membrane-bounded organelle and plasma membrane; INTERACTS WITH 2-methylcholine; aflatoxin B1; arsenous acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: HsT1192; KIAA1342; synaptotagmin IV; synaptotagmin-4; sytIV
Mus musculus (house mouse) : Syt4 (synaptotagmin IV)  MGI  Alliance
Rattus norvegicus (Norway rat) : Syt4 (synaptotagmin 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Syt4 (synaptotagmin 4)
Pan paniscus (bonobo/pygmy chimpanzee) : SYT4 (synaptotagmin 4)
Canis lupus familiaris (dog) : SYT4 (synaptotagmin 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Syt4 (synaptotagmin 4)
Sus scrofa (pig) : SYT4 (synaptotagmin 4)
Chlorocebus sabaeus (African green monkey) : SYT4 (synaptotagmin 4)
Heterocephalus glaber (naked mole-rat) : Syt4 (synaptotagmin 4)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl1843,267,892 - 43,277,535 (-)EnsemblGRCh38hg38GRCh38
GRCh381843,267,892 - 43,277,490 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371840,847,857 - 40,857,615 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361839,101,855 - 39,111,342 (-)NCBINCBI36hg18NCBI36
Build 341839,101,856 - 39,111,342NCBI
Celera1837,656,042 - 37,665,799 (-)NCBI
Cytogenetic Map18q12.3NCBI
HuRef1837,706,367 - 37,716,125 (-)NCBIHuRef
CHM1_11840,774,888 - 40,784,646 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on SYT4
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 68582
Created: 2001-07-11
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.