CCT7 (chaperonin containing TCP1 subunit 7) - Rat Genome Database

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Gene: CCT7 (chaperonin containing TCP1 subunit 7) Homo sapiens
Analyze
Symbol: CCT7
Name: chaperonin containing TCP1 subunit 7
RGD ID: 1315027
HGNC Page HGNC:1622
Description: Enables protein folding chaperone. Involved in chaperone mediated protein folding independent of cofactor and protein stabilization. Located in microtubule. Part of chaperonin-containing T-complex.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: CCT-ETA; CCTETA; Ccth; chaperonin containing T-complex polypeptide 1 subunit 7; chaperonin containing t-complex polypeptide 1, eta subunit; chaperonin containing TCP1, subunit 7 (eta); HIV-1 Nef interacting protein; HIV-1 Nef-interacting protein; MGC110985; Nip7-1; T-complex protein 1 subunit eta; TCP-1-eta; TCP1ETA
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: CCT7P1   CCT7P2  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38273,234,308 - 73,253,005 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl273,233,420 - 73,253,021 (+)EnsemblGRCh38hg38GRCh38
GRCh37273,461,436 - 73,480,133 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36273,314,913 - 73,333,655 (+)NCBINCBI36Build 36hg18NCBI36
Build 34273,373,059 - 73,391,799NCBI
Celera273,312,190 - 73,330,978 (+)NCBICelera
Cytogenetic Map2p13.2NCBI
HuRef273,197,020 - 73,215,809 (+)NCBIHuRef
CHM1_1273,392,171 - 73,410,957 (+)NCBICHM1_1
T2T-CHM13v2.0273,246,421 - 73,265,996 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (ISO)
(1->4)-beta-D-glucan  (ISO)
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
1H-pyrazole  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4-dinitrotoluene  (ISO)
2,6-dinitrotoluene  (ISO)
2-methylcholine  (EXP)
3',5'-cyclic GMP  (EXP)
3H-1,2-dithiole-3-thione  (ISO)
4,4'-sulfonyldiphenol  (EXP)
aflatoxin B1  (EXP)
all-trans-retinoic acid  (EXP)
aminoglutethimide  (EXP)
arsenite(3-)  (EXP)
arsenous acid  (EXP)
benzatropine  (EXP)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (EXP)
bisphenol F  (EXP)
C60 fullerene  (ISO)
cadmium atom  (EXP)
cadmium dichloride  (EXP,ISO)
carbon nanotube  (ISO)
CGP 52608  (EXP)
chlorpyrifos  (ISO)
choline  (ISO)
chromium(6+)  (ISO)
clobetasol  (ISO)
clozapine  (EXP)
coumarin  (EXP)
cyclophosphamide  (ISO)
diarsenic trioxide  (EXP)
Dibutyl phosphate  (EXP)
dibutyl phthalate  (ISO)
diethylstilbestrol  (EXP)
dinophysistoxin 1  (EXP)
doxorubicin  (EXP)
enzyme inhibitor  (EXP)
flutamide  (ISO)
folic acid  (ISO)
gentamycin  (ISO)
hydralazine  (EXP)
ivermectin  (EXP)
L-methionine  (ISO)
L-serine  (EXP)
methidathion  (ISO)
nefazodone  (ISO)
nickel dichloride  (ISO)
nimesulide  (ISO)
okadaic acid  (EXP)
ozone  (ISO)
paracetamol  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (ISO)
PhIP  (ISO)
phlorizin  (ISO)
pirinixic acid  (ISO)
S-nitrosoglutathione  (EXP)
sodium arsenate  (ISO)
sodium arsenite  (EXP)
sodium dichromate  (ISO)
tamoxifen  (ISO)
testosterone  (ISO)
tetrachloromethane  (ISO)
thioacetamide  (ISO)
titanium dioxide  (ISO)
tolcapone  (ISO)
tributylstannane  (ISO)
trimellitic anhydride  (ISO)
triptonide  (ISO)
valdecoxib  (ISO)
valproic acid  (EXP)
vinclozolin  (ISO)
WIN 55212-2  (ISO)
zinc atom  (EXP)
zinc(0)  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cell body  (IEA)
chaperonin-containing T-complex  (IBA,IDA,IEA,IPI,TAS)
cytoplasm  (IEA,TAS)
cytosol  (TAS)
extracellular exosome  (HDA)
microtubule  (IDA,IEA)

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
Dystonia  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8125298   PMID:8982604   PMID:9250675   PMID:9819444   PMID:11532003   PMID:12477932   PMID:14532270   PMID:15347653   PMID:15489334   PMID:15815621   PMID:16055720   PMID:16085932  
PMID:16169070   PMID:16236267   PMID:16497536   PMID:17339318   PMID:17550899   PMID:18029348   PMID:18715871   PMID:18775504   PMID:18782753   PMID:18816836   PMID:19156129   PMID:19193609  
PMID:19380743   PMID:19615732   PMID:19738201   PMID:20193073   PMID:20458337   PMID:20467437   PMID:20473970   PMID:20516061   PMID:20562859   PMID:20877624   PMID:21081503   PMID:21081666  
PMID:21145461   PMID:21319273   PMID:21525035   PMID:21572988   PMID:21654808   PMID:21832049   PMID:21873635   PMID:21900206   PMID:21942715   PMID:21988832   PMID:22133715   PMID:22145905  
PMID:22268729   PMID:22623428   PMID:22658674   PMID:22863883   PMID:22939629   PMID:23011926   PMID:23184937   PMID:23277564   PMID:23292503   PMID:23349634   PMID:23376485   PMID:23383273  
PMID:23398456   PMID:23438482   PMID:23443559   PMID:23455922   PMID:23508102   PMID:23658844   PMID:23703321   PMID:23752268   PMID:23824909   PMID:24104479   PMID:24337577   PMID:24366813  
PMID:24550385   PMID:24711643   PMID:24981860   PMID:25144556   PMID:25147182   PMID:25192599   PMID:25306918   PMID:25324306   PMID:25342745   PMID:25416956   PMID:25437307   PMID:25467444  
PMID:25817432   PMID:25852190   PMID:25900982   PMID:25921289   PMID:25940091   PMID:25959826   PMID:25963833   PMID:26186194   PMID:26217791   PMID:26344197   PMID:26439863   PMID:26460568  
PMID:26472760   PMID:26496610   PMID:26549023   PMID:26638075   PMID:26811472   PMID:26816005   PMID:26831064   PMID:26972000   PMID:27025967   PMID:27114451   PMID:27342126   PMID:27353360  
PMID:27375898   PMID:27591049   PMID:27609421   PMID:27684187   PMID:27705803   PMID:27880917   PMID:28186131   PMID:28302793   PMID:28330616   PMID:28378594   PMID:28443643   PMID:28514442  
PMID:28515276   PMID:28524877   PMID:28561026   PMID:28581483   PMID:28675297   PMID:28685749   PMID:28700943   PMID:28718761   PMID:28977470   PMID:28986522   PMID:29128334   PMID:29229926  
PMID:29298432   PMID:29331416   PMID:29395067   PMID:29467282   PMID:29507755   PMID:29509190   PMID:29531219   PMID:29568061   PMID:29845934   PMID:29991511   PMID:30009671   PMID:30021884  
PMID:30097533   PMID:30154076   PMID:30196744   PMID:30209976   PMID:30442662   PMID:30455355   PMID:30503554   PMID:30559450   PMID:30575818   PMID:30711629   PMID:30745168   PMID:30809309  
PMID:30833792   PMID:30884312   PMID:30890647   PMID:30948266   PMID:30955883   PMID:31091453   PMID:31152661   PMID:31300519   PMID:31353912   PMID:31409639   PMID:31470122   PMID:31515488  
PMID:31527615   PMID:31536960   PMID:31586073   PMID:31617661   PMID:31620119   PMID:31732153   PMID:31751430   PMID:31792442   PMID:31871319   PMID:31980649   PMID:31995728   PMID:32129710  
PMID:32296183   PMID:32347575   PMID:32360748   PMID:32416067   PMID:32529326   PMID:32552912   PMID:32665550   PMID:32683582   PMID:32687490   PMID:32707033   PMID:32807901   PMID:32814053  
PMID:32877691   PMID:32929329   PMID:32994395   PMID:33022573   PMID:33087562   PMID:33137104   PMID:33144677   PMID:33226137   PMID:33239621   PMID:33301849   PMID:33306668   PMID:33545068  
PMID:33567341   PMID:33711283   PMID:33729478   PMID:33731348   PMID:33762435   PMID:33863777   PMID:33916271   PMID:33961781   PMID:34004371   PMID:34079125   PMID:34189442   PMID:34244565  
PMID:34349018   PMID:34373451   PMID:34428256   PMID:34645483   PMID:34687317   PMID:34728620   PMID:34732716   PMID:34901782   PMID:35008187   PMID:35063084   PMID:35073517   PMID:35122331  
PMID:35140242   PMID:35205757   PMID:35235311   PMID:35256949   PMID:35271311   PMID:35338135   PMID:35446349   PMID:35509820   PMID:35530310   PMID:35545034   PMID:35546148   PMID:35563538  
PMID:35776542   PMID:35777956   PMID:35831314   PMID:35844135   PMID:35906200   PMID:35914814   PMID:35944360   PMID:35973989   PMID:36030824   PMID:36055981   PMID:36057605   PMID:36129980  
PMID:36168627   PMID:36180891   PMID:36215168   PMID:36282215   PMID:36376293   PMID:36414381   PMID:36517590   PMID:36526897   PMID:36574265   PMID:36584595   PMID:36652389   PMID:36724073  
PMID:37071682   PMID:37120454   PMID:37223481   PMID:37314216   PMID:37317656   PMID:37506885   PMID:37536630   PMID:37689310   PMID:37827155   PMID:37929963   PMID:38113892   PMID:38172120  
PMID:38334954   PMID:39231216  


Genomics

Comparative Map Data
CCT7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38273,234,308 - 73,253,005 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl273,233,420 - 73,253,021 (+)EnsemblGRCh38hg38GRCh38
GRCh37273,461,436 - 73,480,133 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36273,314,913 - 73,333,655 (+)NCBINCBI36Build 36hg18NCBI36
Build 34273,373,059 - 73,391,799NCBI
Celera273,312,190 - 73,330,978 (+)NCBICelera
Cytogenetic Map2p13.2NCBI
HuRef273,197,020 - 73,215,809 (+)NCBIHuRef
CHM1_1273,392,171 - 73,410,957 (+)NCBICHM1_1
T2T-CHM13v2.0273,246,421 - 73,265,996 (+)NCBIT2T-CHM13v2.0
Cct7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39685,428,487 - 85,445,459 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl685,428,496 - 85,445,457 (+)EnsemblGRCm39 Ensembl
GRCm38685,451,505 - 85,468,477 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl685,451,514 - 85,468,475 (+)EnsemblGRCm38mm10GRCm38
MGSCv37685,401,499 - 85,418,471 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36685,417,731 - 85,434,130 (+)NCBIMGSCv36mm8
Celera687,423,447 - 87,440,419 (+)NCBICelera
Cytogenetic Map6C3NCBI
cM Map637.46NCBI
Cct7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84119,546,730 - 119,563,973 (+)NCBIGRCr8
mRatBN7.24117,989,232 - 118,006,478 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4117,989,232 - 118,006,580 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4123,470,600 - 123,487,845 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04119,245,704 - 119,262,950 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04117,859,060 - 117,876,423 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04117,235,023 - 117,252,265 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4117,235,023 - 117,252,265 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04181,812,638 - 181,829,880 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44119,706,130 - 119,722,975 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14119,950,230 - 119,967,453 (+)NCBI
Celera4106,971,267 - 106,988,502 (+)NCBICelera
Cytogenetic Map4q34NCBI
Cct7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495542412,379,222 - 12,402,161 (-)NCBIChiLan1.0ChiLan1.0
CCT7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21253,127,734 - 53,146,483 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A53,130,467 - 53,149,233 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A73,287,026 - 73,305,792 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A74,775,781 - 74,794,515 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A74,775,781 - 74,794,515 (+)Ensemblpanpan1.1panPan2
LOC100856782
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13437,026,053 - 37,027,839 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3446,037,678 - 46,039,504 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03437,111,520 - 37,113,356 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1750,442,388 - 50,498,676 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13437,048,532 - 37,050,353 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03437,018,069 - 37,019,859 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03437,275,388 - 37,277,179 (-)NCBIUU_Cfam_GSD_1.0
Cct7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629211,537,766 - 11,553,865 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649117,017,687 - 17,033,855 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649117,017,687 - 17,033,526 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CCT7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl369,526,534 - 69,546,548 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1369,527,238 - 69,540,489 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2372,730,662 - 72,743,914 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CCT7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11433,921,100 - 33,940,204 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1433,921,247 - 33,939,404 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604578,143,260 - 78,161,620 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cct7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624762387,712 - 410,196 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in CCT7
27 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
NM_006429.4(CCT7):c.1574C>T (p.Ser525Leu) single nucleotide variant Myocardial infarction, susceptibility to, 1 [RCV000077778] Chr2:73252803 [GRCh38]
Chr2:73479931 [GRCh37]
Chr2:2p13.2		 pathogenic
GRCh38/hg38 2p16.1-11.2(chr2:58279519-83586962)x3 copy number gain See cases [RCV000136053] Chr2:58279519..83586962 [GRCh38]
Chr2:58506654..83814086 [GRCh37]
Chr2:58360158..83667597 [NCBI36]
Chr2:2p16.1-11.2		 pathogenic
GRCh38/hg38 2p16.3-11.2(chr2:47620388-86702722)x3 copy number gain See cases [RCV000137586] Chr2:47620388..86702722 [GRCh38]
Chr2:47847527..86929845 [GRCh37]
Chr2:47701031..86783356 [NCBI36]
Chr2:2p16.3-11.2		 uncertain significance
GRCh38/hg38 2p25.1-11.2(chr2:7495123-87705899)x3 copy number gain See cases [RCV000141494] Chr2:7495123..87705899 [GRCh38]
Chr2:7635254..88005418 [GRCh37]
Chr2:7552705..87786533 [NCBI36]
Chr2:2p25.1-11.2		 benign
GRCh37/hg19 2p25.3-q37.3(chr2:14238-243048760)x3 copy number gain not provided [RCV000752802] Chr2:14238..243048760 [GRCh37]
Chr2:2p25.3-q37.3		 pathogenic
GRCh37/hg19 2p13.2-13.1(chr2:73477212-74065941)x1 copy number loss See cases [RCV000448067] Chr2:73477212..74065941 [GRCh37]
Chr2:2p13.2-13.1		 uncertain significance
GRCh37/hg19 2p15-11.2(chr2:62245236-86978895)x3 copy number gain See cases [RCV000448688] Chr2:62245236..86978895 [GRCh37]
Chr2:2p15-11.2		 pathogenic
GRCh37/hg19 2p25.3-q37.3(chr2:12771-242783384) copy number gain See cases [RCV000512056] Chr2:12771..242783384 [GRCh37]
Chr2:2p25.3-q37.3		 pathogenic
GRCh37/hg19 2p25.3-q37.3(chr2:12771-242783384)x3 copy number gain See cases [RCV000511212] Chr2:12771..242783384 [GRCh37]
Chr2:2p25.3-q37.3		 pathogenic
NM_006429.4(CCT7):c.1588C>T (p.Pro530Ser) single nucleotide variant not specified [RCV004315384] Chr2:73252817 [GRCh38]
Chr2:73479945 [GRCh37]
Chr2:2p13.2		 uncertain significance
NM_006429.4(CCT7):c.1615C>T (p.Arg539Cys) single nucleotide variant not specified [RCV004295956] Chr2:73252844 [GRCh38]
Chr2:73479972 [GRCh37]
Chr2:2p13.2		 uncertain significance
NM_006429.4(CCT7):c.1555A>G (p.Thr519Ala) single nucleotide variant not specified [RCV004326537] Chr2:73252784 [GRCh38]
Chr2:73479912 [GRCh37]
Chr2:2p13.2		 uncertain significance
Single allele duplication not provided [RCV000677942] Chr2:63671346..85698002 [GRCh37]
Chr2:2p15-11.2		 pathogenic
Single allele deletion not provided [RCV000714264] Chr2:40608411..146900718 [GRCh37]
Chr2:2p22.1-q22.3		 likely pathogenic
GRCh37/hg19 2p25.3-q37.3(chr2:15672-243101834)x3 copy number gain not provided [RCV000752804] Chr2:15672..243101834 [GRCh37]
Chr2:2p25.3-q37.3		 pathogenic
GRCh37/hg19 2p25.3-q37.3(chr2:1-243199373) copy number gain Mosaic trisomy 2 [RCV002280628] Chr2:1..243199373 [GRCh37]
Chr2:2p25.3-q37.3		 pathogenic
NC_000002.11:g.(?_71004499)_(74779761_?)del deletion Dystonic disorder [RCV003113211]|Methylmalonic acidemia due to methylmalonyl-CoA epimerase deficiency [RCV003113210]|not provided [RCV003107716] Chr2:71004499..74779761 [GRCh37]
Chr2:2p13.3-13.1		 pathogenic|no classifications from unflagged records
NC_000002.11:g.(?_73114549)_(73836749_?)dup duplication Alstrom syndrome [RCV001365067] Chr2:73114549..73836749 [GRCh37]
Chr2:2p13.2-13.1		 uncertain significance
GRCh37/hg19 2p13.2-13.1(chr2:73477212-74065941) copy number loss not specified [RCV002053150] Chr2:73477212..74065941 [GRCh37]
Chr2:2p13.2-13.1		 uncertain significance
NC_000002.11:g.(?_72359356)_(74779761_?)del deletion MOGS-congenital disorder of glycosylation [RCV003109485]|not provided [RCV003116543] Chr2:72359356..74779761 [GRCh37]
Chr2:2p13.2-13.1		 pathogenic|no classifications from unflagged records
NC_000002.11:g.(?_69240632)_(74779761_?)dup duplication not provided [RCV003122858] Chr2:69240632..74779761 [GRCh37]
Chr2:2p13.3-13.1		 uncertain significance
GRCh37/hg19 2p25.1-q13(chr2:11504318-111365996)x1 copy number loss See cases [RCV002287563] Chr2:11504318..111365996 [GRCh37]
Chr2:2p25.1-q13		 pathogenic
NM_006429.4(CCT7):c.1546G>A (p.Val516Ile) single nucleotide variant not specified [RCV004223662] Chr2:73252775 [GRCh38]
Chr2:73479903 [GRCh37]
Chr2:2p13.2		 uncertain significance
NM_006429.4(CCT7):c.1283C>T (p.Pro428Leu) single nucleotide variant not specified [RCV004157635] Chr2:73251305 [GRCh38]
Chr2:73478433 [GRCh37]
Chr2:2p13.2		 uncertain significance
NM_006429.4(CCT7):c.710T>C (p.Ile237Thr) single nucleotide variant not specified [RCV004087235] Chr2:73247853 [GRCh38]
Chr2:73474981 [GRCh37]
Chr2:2p13.2		 uncertain significance
NM_006429.4(CCT7):c.1540G>A (p.Val514Met) single nucleotide variant not specified [RCV004197745] Chr2:73252769 [GRCh38]
Chr2:73479897 [GRCh37]
Chr2:2p13.2		 uncertain significance
NM_006429.4(CCT7):c.1517C>T (p.Ala506Val) single nucleotide variant not specified [RCV004119002] Chr2:73252746 [GRCh38]
Chr2:73479874 [GRCh37]
Chr2:2p13.2		 uncertain significance
NM_006429.4(CCT7):c.386C>T (p.Thr129Ile) single nucleotide variant not specified [RCV004212532] Chr2:73243122 [GRCh38]
Chr2:73470250 [GRCh37]
Chr2:2p13.2		 uncertain significance
NM_006429.4(CCT7):c.1505C>T (p.Ala502Val) single nucleotide variant not specified [RCV004250125] Chr2:73252734 [GRCh38]
Chr2:73479862 [GRCh37]
Chr2:2p13.2		 uncertain significance
NM_006429.4(CCT7):c.209A>G (p.Asp70Gly) single nucleotide variant not specified [RCV004271015] Chr2:73240485 [GRCh38]
Chr2:73467613 [GRCh37]
Chr2:2p13.2		 uncertain significance
NM_006429.4(CCT7):c.877C>G (p.Leu293Val) single nucleotide variant not specified [RCV004317531] Chr2:73249084 [GRCh38]
Chr2:73476212 [GRCh37]
Chr2:2p13.2		 uncertain significance
NM_006429.4(CCT7):c.1399C>G (p.Arg467Gly) single nucleotide variant not specified [RCV004253358] Chr2:73251421 [GRCh38]
Chr2:73478549 [GRCh37]
Chr2:2p13.2		 uncertain significance
NM_006429.4(CCT7):c.1502A>T (p.Asn501Ile) single nucleotide variant not specified [RCV004346631] Chr2:73252731 [GRCh38]
Chr2:73479859 [GRCh37]
Chr2:2p13.2		 uncertain significance
NM_006429.4(CCT7):c.1185C>G (p.Ile395Met) single nucleotide variant not provided [RCV003457296] Chr2:73250420 [GRCh38]
Chr2:73477548 [GRCh37]
Chr2:2p13.2		 uncertain significance
NM_006429.4(CCT7):c.427G>A (p.Val143Met) single nucleotide variant not specified [RCV004364109] Chr2:73244030 [GRCh38]
Chr2:73471158 [GRCh37]
Chr2:2p13.2		 uncertain significance
NM_006429.4(CCT7):c.544G>A (p.Ala182Thr) single nucleotide variant not specified [RCV004365584] Chr2:73244641 [GRCh38]
Chr2:73471769 [GRCh37]
Chr2:2p13.2		 uncertain significance
GRCh37/hg19 2p13.3-12(chr2:71076472-76368354)x1 copy number loss not specified [RCV003986388] Chr2:71076472..76368354 [GRCh37]
Chr2:2p13.3-12		 likely pathogenic
NM_006429.4(CCT7):c.343G>C (p.Gly115Arg) single nucleotide variant not specified [RCV004433093] Chr2:73243079 [GRCh38]
Chr2:73470207 [GRCh37]
Chr2:2p13.2		 uncertain significance
NM_006429.4(CCT7):c.1529C>T (p.Ala510Val) single nucleotide variant not specified [RCV004433091] Chr2:73252758 [GRCh38]
Chr2:73479886 [GRCh37]
Chr2:2p13.2		 uncertain significance
NM_006429.4(CCT7):c.896C>G (p.Ala299Gly) single nucleotide variant not specified [RCV004433095] Chr2:73249103 [GRCh38]
Chr2:73476231 [GRCh37]
Chr2:2p13.2		 uncertain significance
NM_006429.4(CCT7):c.1412G>C (p.Gly471Ala) single nucleotide variant not specified [RCV004433089] Chr2:73252641 [GRCh38]
Chr2:73479769 [GRCh37]
Chr2:2p13.2		 uncertain significance
NM_006429.4(CCT7):c.1450A>G (p.Ile484Val) single nucleotide variant not specified [RCV004433090] Chr2:73252679 [GRCh38]
Chr2:73479807 [GRCh37]
Chr2:2p13.2		 uncertain significance
NM_006429.4(CCT7):c.1096A>G (p.Lys366Glu) single nucleotide variant not specified [RCV004433088] Chr2:73250331 [GRCh38]
Chr2:73477459 [GRCh37]
Chr2:2p13.2		 uncertain significance
NM_006429.4(CCT7):c.32A>T (p.Glu11Val) single nucleotide variant not specified [RCV004433092] Chr2:73239668 [GRCh38]
Chr2:73466796 [GRCh37]
Chr2:2p13.2		 uncertain significance
NM_006429.4(CCT7):c.344G>T (p.Gly115Val) single nucleotide variant not specified [RCV004433094] Chr2:73243080 [GRCh38]
Chr2:73470208 [GRCh37]
Chr2:2p13.2		 uncertain significance
NM_006429.4(CCT7):c.1613G>A (p.Gly538Asp) single nucleotide variant not specified [RCV004606424] Chr2:73252842 [GRCh38]
Chr2:73479970 [GRCh37]
Chr2:2p13.2		 uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:3469
Count of miRNA genes:885
Interacting mature miRNAs:1053
Transcripts:ENST00000258091, ENST00000398422, ENST00000399032, ENST00000409924, ENST00000461290, ENST00000464397, ENST00000469844, ENST00000471927, ENST00000473197, ENST00000473786, ENST00000480489, ENST00000482064, ENST00000488856, ENST00000492253, ENST00000537131, ENST00000538797, ENST00000539919, ENST00000540468
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407353124GWAS1002100_Heducational attainment QTL GWAS1002100 (human)4e-16educational attainment27324336973243370Human
407353123GWAS1002099_Heducational attainment QTL GWAS1002099 (human)3e-08educational attainment27323629573236296Human
406986421GWAS635397_Hintelligence QTL GWAS635397 (human)2e-09intelligence27324336973243370Human
406920299GWAS569275_HN-acetylleucine measurement QTL GWAS569275 (human)4e-17N-acetylleucine measurement27324529673245297Human
407107501GWAS756477_Hself reported educational attainment QTL GWAS756477 (human)2e-10self reported educational attainment27324336973243370Human

Markers in Region
RH41801  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37273,479,901 - 73,480,113UniSTSGRCh37
Build 36273,333,409 - 73,333,621RGDNCBI36
Celera273,330,729 - 73,330,941RGD
Cytogenetic Map2p13.2UniSTS
HuRef273,215,560 - 73,215,772UniSTS
CCT7  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37273,476,230 - 73,476,974UniSTSGRCh37
GRCh376150,201,975 - 150,202,080UniSTSGRCh37
Celera273,327,056 - 73,327,800UniSTS
Celera6150,936,638 - 150,936,743UniSTS
HuRef6147,767,463 - 147,767,568UniSTS
HuRef273,211,886 - 73,212,630UniSTS


Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
pharyngeal arch
renal system
reproductive system
respiratory system
sensory system
visual system
1204 2439 2788 2253 4974 1726 2351 6 624 1951 465 2270 7306 6472 53 3734 1 852 1744 1617 175 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NG_047121 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001009570 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001166284 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001166285 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_006429 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_029402 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_029403 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011532478 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011532479 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054340196 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC010913 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF026292 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI571508 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK098549 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK098825 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK222478 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK291961 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK293175 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK293597 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK297846 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK298153 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK302078 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC019296 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC088351 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BM558355 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BM918058 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471053 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068276 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR456719 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR536511 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CX781741 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DC362157 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DC395264 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KF456675 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U83843 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENST00000258091   ⟹   ENSP00000258091
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl273,234,308 - 73,253,005 (+)Ensembl
Ensembl Acc Id: ENST00000398422   ⟹   ENSP00000381456
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl273,234,308 - 73,253,004 (+)Ensembl
Ensembl Acc Id: ENST00000399032   ⟹   ENSP00000412996
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl273,234,308 - 73,244,029 (+)Ensembl
Ensembl Acc Id: ENST00000409924   ⟹   ENSP00000386978
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl273,234,309 - 73,247,789 (+)Ensembl
Ensembl Acc Id: ENST00000461290
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl273,234,269 - 73,244,511 (+)Ensembl
Ensembl Acc Id: ENST00000464397
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl273,234,307 - 73,240,147 (+)Ensembl
Ensembl Acc Id: ENST00000469844
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl273,233,429 - 73,244,630 (+)Ensembl
Ensembl Acc Id: ENST00000471927
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl273,233,420 - 73,243,108 (+)Ensembl
Ensembl Acc Id: ENST00000473197
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl273,233,445 - 73,240,548 (+)Ensembl
Ensembl Acc Id: ENST00000473786
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl273,234,336 - 73,249,844 (+)Ensembl
Ensembl Acc Id: ENST00000480489
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl273,234,309 - 73,243,193 (+)Ensembl
Ensembl Acc Id: ENST00000482064
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl273,239,101 - 73,243,130 (+)Ensembl
Ensembl Acc Id: ENST00000488856
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl273,243,846 - 73,249,061 (+)Ensembl
Ensembl Acc Id: ENST00000492253
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl273,233,459 - 73,243,082 (+)Ensembl
Ensembl Acc Id: ENST00000539919   ⟹   ENSP00000437824
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl273,234,236 - 73,253,021 (+)Ensembl
Ensembl Acc Id: ENST00000540468   ⟹   ENSP00000442058
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl273,234,236 - 73,253,021 (+)Ensembl
Ensembl Acc Id: ENST00000626868   ⟹   ENSP00000487267
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl273,239,545 - 73,243,134 (+)Ensembl
RefSeq Acc Id: NM_001009570   ⟹   NP_001009570
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38273,234,308 - 73,253,005 (+)NCBI
GRCh37273,461,364 - 73,480,150 (+)RGD
Build 36273,314,913 - 73,333,655 (+)NCBI Archive
Celera273,312,190 - 73,330,978 (+)RGD
HuRef273,197,020 - 73,215,809 (+)RGD
CHM1_1273,392,171 - 73,410,957 (+)NCBI
T2T-CHM13v2.0273,247,297 - 73,265,996 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001166284   ⟹   NP_001159756
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38273,234,308 - 73,253,005 (+)NCBI
GRCh37273,461,364 - 73,480,150 (+)RGD
Celera273,312,190 - 73,330,978 (+)RGD
HuRef273,197,020 - 73,215,809 (+)RGD
CHM1_1273,392,171 - 73,410,957 (+)NCBI
T2T-CHM13v2.0273,247,297 - 73,265,996 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001166285   ⟹   NP_001159757
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38273,234,308 - 73,253,005 (+)NCBI
GRCh37273,461,364 - 73,480,150 (+)RGD
Celera273,312,190 - 73,330,978 (+)RGD
HuRef273,197,020 - 73,215,809 (+)RGD
CHM1_1273,392,171 - 73,410,957 (+)NCBI
T2T-CHM13v2.0273,247,297 - 73,265,996 (+)NCBI
Sequence:
RefSeq Acc Id: NM_006429   ⟹   NP_006420
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38273,234,308 - 73,253,005 (+)NCBI
GRCh37273,461,364 - 73,480,150 (+)RGD
Build 36273,314,913 - 73,333,655 (+)NCBI Archive
Celera273,312,190 - 73,330,978 (+)RGD
HuRef273,197,020 - 73,215,809 (+)RGD
CHM1_1273,392,171 - 73,410,957 (+)NCBI
T2T-CHM13v2.0273,247,297 - 73,265,996 (+)NCBI
Sequence:
RefSeq Acc Id: NR_029402
RefSeq Status: REVIEWED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38273,234,308 - 73,253,005 (+)NCBI
GRCh37273,461,364 - 73,480,150 (+)RGD
Celera273,312,190 - 73,330,978 (+)RGD
HuRef273,197,020 - 73,215,809 (+)RGD
CHM1_1273,392,171 - 73,410,957 (+)NCBI
T2T-CHM13v2.0273,247,297 - 73,265,996 (+)NCBI
Sequence:
RefSeq Acc Id: NR_029403
RefSeq Status: REVIEWED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38273,234,308 - 73,253,005 (+)NCBI
GRCh37273,461,364 - 73,480,150 (+)RGD
Celera273,312,190 - 73,330,978 (+)RGD
HuRef273,197,020 - 73,215,809 (+)RGD
CHM1_1273,392,171 - 73,410,957 (+)NCBI
T2T-CHM13v2.0273,247,297 - 73,265,996 (+)NCBI
Sequence:
RefSeq Acc Id: XM_054340196   ⟹   XP_054196171
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0273,246,421 - 73,265,996 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001009570 (Get FASTA)   NCBI Sequence Viewer  
  NP_001159756 (Get FASTA)   NCBI Sequence Viewer  
  NP_001159757 (Get FASTA)   NCBI Sequence Viewer  
  NP_006420 (Get FASTA)   NCBI Sequence Viewer  
  XP_054196171 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAB41437 (Get FASTA)   NCBI Sequence Viewer  
  AAC96011 (Get FASTA)   NCBI Sequence Viewer  
  AAH19296 (Get FASTA)   NCBI Sequence Viewer  
  AAH88351 (Get FASTA)   NCBI Sequence Viewer  
  AAX88902 (Get FASTA)   NCBI Sequence Viewer  
  BAD96198 (Get FASTA)   NCBI Sequence Viewer  
  BAF84650 (Get FASTA)   NCBI Sequence Viewer  
  BAH11465 (Get FASTA)   NCBI Sequence Viewer  
  BAH11543 (Get FASTA)   NCBI Sequence Viewer  
  BAH12675 (Get FASTA)   NCBI Sequence Viewer  
  BAH12733 (Get FASTA)   NCBI Sequence Viewer  
  BAH13620 (Get FASTA)   NCBI Sequence Viewer  
  CAG33000 (Get FASTA)   NCBI Sequence Viewer  
  CAG38749 (Get FASTA)   NCBI Sequence Viewer  
  EAW99738 (Get FASTA)   NCBI Sequence Viewer  
  EAW99739 (Get FASTA)   NCBI Sequence Viewer  
  EAW99740 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSP00000258091
  ENSP00000258091.5
  ENSP00000381456
  ENSP00000381456.2
  ENSP00000386978.3
  ENSP00000412996.1
  ENSP00000437824
  ENSP00000437824.1
  ENSP00000442058
  ENSP00000442058.1
GenBank Protein Q99832 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_006420   ⟸   NM_006429
- Peptide Label: isoform a
- UniProtKB: O14871 (UniProtKB/Swiss-Prot),   B7Z4Z7 (UniProtKB/Swiss-Prot),   B7Z4T9 (UniProtKB/Swiss-Prot),   B7WNW9 (UniProtKB/Swiss-Prot),   A8MWI8 (UniProtKB/Swiss-Prot),   A8K7E6 (UniProtKB/Swiss-Prot),   Q6FI26 (UniProtKB/Swiss-Prot),   Q99832 (UniProtKB/Swiss-Prot),   Q53HV2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001009570   ⟸   NM_001009570
- Peptide Label: isoform b
- UniProtKB: Q99832 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001159756   ⟸   NM_001166284
- Peptide Label: isoform c
- UniProtKB: B7Z7I4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001159757   ⟸   NM_001166285
- Peptide Label: isoform d
- UniProtKB: Q53HV2 (UniProtKB/TrEMBL),   Q6IBT3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSP00000381456   ⟸   ENST00000398422
Ensembl Acc Id: ENSP00000412996   ⟸   ENST00000399032
Ensembl Acc Id: ENSP00000258091   ⟸   ENST00000258091
Ensembl Acc Id: ENSP00000487267   ⟸   ENST00000626868
Ensembl Acc Id: ENSP00000437824   ⟸   ENST00000539919
Ensembl Acc Id: ENSP00000386978   ⟸   ENST00000409924
Ensembl Acc Id: ENSP00000442058   ⟸   ENST00000540468
RefSeq Acc Id: XP_054196171   ⟸   XM_054340196
- Peptide Label: isoform X1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q99832-F1-model_v2 AlphaFold Q99832 1-543 view protein structure

Promoters
RGD ID:6860682
Promoter ID:EPDNEW_H3506
Type:initiation region
Name:CCT7_1
Description:chaperonin containing TCP1 subunit 7
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38273,234,318 - 73,234,378EPDNEW
RGD ID:6796912
Promoter ID:HG_KWN:33248
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   K562,   Lymphoblastoid
Transcripts:NM_032319,   OTTHUMT00000327711,   OTTHUMT00000327713,   OTTHUMT00000327745,   OTTHUMT00000327746,   OTTHUMT00000327747,   OTTHUMT00000327748
Position:
Human AssemblyChrPosition (strand)Source
Build 36273,313,341 - 73,314,137 (-)MPROMDB
RGD ID:6796958
Promoter ID:HG_KWN:33249
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:NM_001009570,   NM_001166284,   NM_001166285,   NM_006429,   NR_029402,   NR_029403,   OTTHUMT00000327744,   OTTHUMT00000327750,   OTTHUMT00000327751,   OTTHUMT00000327752,   OTTHUMT00000327753,   OTTHUMT00000327754,   OTTHUMT00000327756,   UC010FEU.1
Position:
Human AssemblyChrPosition (strand)Source
Build 36273,314,161 - 73,315,042 (+)MPROMDB
RGD ID:6851312
Promoter ID:EP73454
Type:initiation region
Name:HS_CCT7
Description:Chaperonin containing TCP1, subunit 7 (eta).
SO ACC ID:SO:0000170
Source:EPD (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:NEDO full length human cDNA sequencing project.; Oligo-capping
Position:
Human AssemblyChrPosition (strand)Source
Build 36273,314,944 - 73,315,004EPD
RGD ID:6796962
Promoter ID:HG_KWN:33250
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Lymphoblastoid
Transcripts:OTTHUMT00000327749
Position:
Human AssemblyChrPosition (strand)Source
Build 36273,319,011 - 73,319,822 (+)MPROMDB
RGD ID:6796961
Promoter ID:HG_KWN:33252
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Lymphoblastoid
Transcripts:OTTHUMT00000327755
Position:
Human AssemblyChrPosition (strand)Source
Build 36273,328,771 - 73,330,162 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:1622 AgrOrtholog
COSMIC CCT7 COSMIC
Ensembl Genes ENSG00000135624 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000258091 ENTREZGENE
  ENST00000258091.10 UniProtKB/Swiss-Prot
  ENST00000398422 ENTREZGENE
  ENST00000398422.2 UniProtKB/Swiss-Prot
  ENST00000399032.2 UniProtKB/TrEMBL
  ENST00000409924.7 UniProtKB/TrEMBL
  ENST00000539919 ENTREZGENE
  ENST00000539919.5 UniProtKB/Swiss-Prot
  ENST00000540468 ENTREZGENE
  ENST00000540468.5 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.560.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.30.260.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.50.7.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000135624 GTEx
HGNC ID HGNC:1622 ENTREZGENE
Human Proteome Map CCT7 Human Proteome Map
InterPro Chap_CCT_eta UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Chaperone_TCP-1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Chaperonin_TCP-1_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cpn60/TCP-1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GroEL-like_apical_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GROEL-like_equatorial_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TCP-1-like_intermed_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TCP-1_chaperonin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:10574 UniProtKB/Swiss-Prot
NCBI Gene 10574 ENTREZGENE
OMIM 605140 OMIM
PANTHER PTHR11353 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11353:SF22 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Cpn60_TCP1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA26185 PharmGKB
PRINTS TCOMPLEXTCP1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE TCP1_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TCP1_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TCP1_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48592 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF52029 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF54849 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A8K7E6 ENTREZGENE
  A8MWI8 ENTREZGENE
  B7WNW9 ENTREZGENE
  B7Z1C9_HUMAN UniProtKB/TrEMBL
  B7Z4T9 ENTREZGENE
  B7Z4Z7 ENTREZGENE
  B7Z7I4 ENTREZGENE, UniProtKB/TrEMBL
  F8WAM2_HUMAN UniProtKB/TrEMBL
  F8WBP8_HUMAN UniProtKB/TrEMBL
  O14871 ENTREZGENE
  Q53HV2 ENTREZGENE, UniProtKB/TrEMBL
  Q6FI26 ENTREZGENE
  Q6IBT3 ENTREZGENE, UniProtKB/TrEMBL
  Q99832 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary A8K7E6 UniProtKB/Swiss-Prot
  A8MWI8 UniProtKB/Swiss-Prot
  B7WNW9 UniProtKB/Swiss-Prot
  B7Z4T9 UniProtKB/Swiss-Prot
  B7Z4Z7 UniProtKB/Swiss-Prot
  O14871 UniProtKB/Swiss-Prot
  Q6FI26 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-01-12 CCT7  chaperonin containing TCP1 subunit 7    chaperonin containing TCP1, subunit 7 (eta)  Symbol and/or name change 5135510 APPROVED