HRH1 (histamine receptor H1) - Rat Genome Database

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Gene: HRH1 (histamine receptor H1) Homo sapiens
Analyze
Symbol: HRH1
Name: histamine receptor H1
RGD ID: 736085
HGNC Page HGNC:5182
Description: Enables histamine receptor activity. Involved in G protein-coupled receptor signaling pathway and cellular response to histamine. Located in cytosol. Is active in plasma membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: H1-R; H1R; HH1R; hisH1; histamine H(1) receptor; histamine H1 receptor; histamine receptor h 1; histamine receptor, subclass H1
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38311,137,238 - 11,263,557 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl311,137,093 - 11,263,557 (+)EnsemblGRCh38hg38GRCh38
GRCh37311,178,924 - 11,305,243 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36311,153,779 - 11,279,939 (+)NCBINCBI36Build 36hg18NCBI36
Build 34311,269,399 - 11,279,415NCBI
Celera311,114,216 - 11,240,363 (+)NCBICelera
Cytogenetic Map3p25.3NCBI
HuRef311,113,586 - 11,239,205 (+)NCBIHuRef
CHM1_1311,128,810 - 11,254,995 (+)NCBICHM1_1
T2T-CHM13v2.0311,131,678 - 11,258,484 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(S)-ropivacaine  (EXP)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2-palmitoylglycerol  (EXP)
2-pyridylethylamine  (ISO)
3',5'-cyclic AMP  (EXP)
3,4-methylenedioxymethamphetamine  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (EXP)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (EXP)
6-propyl-2-thiouracil  (ISO)
aflatoxin B1  (EXP)
Aflatoxin B2 alpha  (EXP)
all-trans-retinoic acid  (ISO)
aminophylline  (ISO)
ammonium chloride  (ISO)
asbestos  (EXP)
astemizole  (EXP,ISO)
atrazine  (ISO)
azatadine  (EXP)
azelastine  (EXP)
Bardoxolone methyl  (EXP)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (EXP)
betahistine  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
bupivacaine  (EXP)
cadmium dichloride  (EXP)
calcium atom  (EXP)
calcium(0)  (EXP)
cannabidiol  (EXP)
cetirizine  (EXP)
chlordecone  (ISO)
chlorphenamine  (EXP,ISO)
cimetidine  (ISO)
cisplatin  (EXP)
clemastine  (EXP)
clobenpropit  (ISO)
clozapine  (EXP)
crocidolite asbestos  (EXP)
CU-O LINKAGE  (EXP)
cyclosporin A  (EXP)
desloratadine  (EXP)
dexamethasone  (ISO)
dimetindene  (EXP)
diphenhydramine  (EXP,ISO)
diphenylpyraline  (EXP)
dopamine  (ISO)
doxorubicin  (EXP)
epinastine  (ISO)
epoxiconazole  (ISO)
erythromycin A  (ISO)
ethanol  (ISO)
Fexofenadine hydrochloride  (EXP,ISO)
fluoxetine  (EXP)
folic acid  (ISO)
fructose  (ISO)
fulvestrant  (EXP)
galangin  (ISO)
gallic acid  (EXP)
GTP  (EXP)
histamine  (EXP,ISO)
hydroxyzine  (EXP)
lamotrigine  (EXP)
lead(0)  (EXP)
lidocaine  (EXP)
lipopolysaccharide  (EXP)
loratadine  (EXP)
manganese(II) chloride  (EXP)
mepyramine  (EXP,ISO)
methotrexate  (EXP)
milnacipran  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
morphine  (ISO)
N-Nitrosopyrrolidine  (EXP)
nickel atom  (EXP,ISO)
niclosamide  (EXP)
olanzapine  (EXP,ISO)
Olopatadine hydrochloride  (EXP,ISO)
paracetamol  (EXP)
paroxetine  (ISO)
phorbol 13-acetate 12-myristate  (EXP)
potassium atom  (ISO)
potassium chromate  (EXP)
procaine  (EXP)
promethazine  (EXP)
quercetin  (EXP,ISO)
resveratrol  (EXP)
rifampicin  (EXP)
Ro 31-8220  (ISO)
rotenone  (ISO)
scopolamine  (ISO)
silicon dioxide  (EXP)
sodium arsenite  (EXP)
tacrine  (ISO)
Terfenadine  (ISO)
tetracaine  (EXP)
tetrachloromethane  (ISO)
toluene 2,4-diisocyanate  (ISO)
tributylstannane  (EXP)
Tripelennamine  (ISO)
triprolidine  (EXP,ISO)
valproic acid  (EXP)
zinc atom  (EXP)
zinc(0)  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytosol  (IDA)
dendrite  (IBA)
membrane  (IEA)
plasma membrane  (IBA,IDA,IEA,ISS,TAS)
synapse  (IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:2670975   PMID:2886904   PMID:2891264   PMID:7925364   PMID:8003029   PMID:8045566   PMID:8280179   PMID:8590995   PMID:8666296   PMID:9311023   PMID:9794809   PMID:10569698  
PMID:10818238   PMID:10973974   PMID:11603849   PMID:11898002   PMID:11994709   PMID:12218662   PMID:12429384   PMID:12477932   PMID:12680587   PMID:12755404   PMID:12757445   PMID:15328002  
PMID:15342556   PMID:15542600   PMID:15820830   PMID:15928828   PMID:15928843   PMID:15953854   PMID:16027157   PMID:16344560   PMID:16408006   PMID:16484687   PMID:16491014   PMID:16547808  
PMID:16705383   PMID:16754659   PMID:16760260   PMID:16888049   PMID:17122961   PMID:17243823   PMID:17517105   PMID:17547532   PMID:17627982   PMID:17637176   PMID:18029348   PMID:18240029  
PMID:18258331   PMID:18345497   PMID:18366640   PMID:18446005   PMID:18498711   PMID:18511496   PMID:18548114   PMID:18577758   PMID:18682391   PMID:18814859   PMID:19156168   PMID:19193342  
PMID:19271144   PMID:19443731   PMID:19913013   PMID:19913121   PMID:20237496   PMID:20602615   PMID:20628086   PMID:20800603   PMID:21255012   PMID:21433074   PMID:21686228   PMID:21697825  
PMID:21730054   PMID:21873635   PMID:21937795   PMID:22169095   PMID:22860191   PMID:23132961   PMID:23225320   PMID:23382691   PMID:23414213   PMID:23609395   PMID:23677734   PMID:23900020  
PMID:23962049   PMID:24236486   PMID:24535227   PMID:25241761   PMID:25293806   PMID:25295384   PMID:25582918   PMID:25664905   PMID:25682263   PMID:25909280   PMID:26635083   PMID:26752109  
PMID:27468652   PMID:27871651   PMID:28298427   PMID:28391980   PMID:28400155   PMID:29063596   PMID:29507755   PMID:29548821   PMID:30168182   PMID:31406237   PMID:31740780   PMID:33080103  
PMID:33828102   PMID:33918180   PMID:34595742   PMID:34638832   PMID:35031480   PMID:35705043   PMID:36732336   PMID:37201878   PMID:37300703   PMID:37977823   PMID:38542369   PMID:38953634  


Genomics

Comparative Map Data
HRH1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38311,137,238 - 11,263,557 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl311,137,093 - 11,263,557 (+)EnsemblGRCh38hg38GRCh38
GRCh37311,178,924 - 11,305,243 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36311,153,779 - 11,279,939 (+)NCBINCBI36Build 36hg18NCBI36
Build 34311,269,399 - 11,279,415NCBI
Celera311,114,216 - 11,240,363 (+)NCBICelera
Cytogenetic Map3p25.3NCBI
HuRef311,113,586 - 11,239,205 (+)NCBIHuRef
CHM1_1311,128,810 - 11,254,995 (+)NCBICHM1_1
T2T-CHM13v2.0311,131,678 - 11,258,484 (+)NCBIT2T-CHM13v2.0
Hrh1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396114,374,897 - 114,459,432 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6114,374,897 - 114,460,257 (+)EnsemblGRCm39 Ensembl
GRCm386114,397,936 - 114,483,298 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6114,397,936 - 114,483,296 (+)EnsemblGRCm38mm10GRCm38
MGSCv376114,347,930 - 114,433,290 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366114,363,531 - 114,448,891 (+)NCBIMGSCv36mm8
Celera6116,219,517 - 116,304,883 (+)NCBICelera
Cytogenetic Map6E3NCBI
cM Map653.05NCBI
Hrh1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84149,120,511 - 149,204,267 (+)NCBIGRCr8
mRatBN7.24147,564,963 - 147,649,353 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4147,645,995 - 147,647,455 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4152,949,786 - 153,033,522 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04148,730,672 - 148,814,402 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04147,360,109 - 147,443,854 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04146,374,596 - 146,458,148 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4146,455,332 - 146,457,074 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04209,668,412 - 209,751,766 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44150,431,239 - 150,432,699 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14150,676,079 - 150,677,540 (+)NCBI
Celera4136,197,254 - 136,198,714 (+)NCBICelera
RH 3.4 Map4950.0RGD
Cytogenetic Map4q42NCBI
Hrh1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542914,067,405 - 14,068,853 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542914,022,332 - 14,069,931 (+)NCBIChiLan1.0ChiLan1.0
HRH1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2211,134,626 - 11,259,909 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1311,139,386 - 11,264,669 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0311,074,451 - 11,199,871 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1311,439,705 - 11,545,509 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl311,541,294 - 11,542,757 (+)Ensemblpanpan1.1panPan2
HRH1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1207,160,903 - 7,236,147 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl207,162,393 - 7,235,869 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha207,195,842 - 7,270,946 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0207,190,337 - 7,265,418 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl207,190,251 - 7,265,315 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1206,906,408 - 6,981,475 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0207,262,781 - 7,337,859 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0207,234,680 - 7,309,540 (-)NCBIUU_Cfam_GSD_1.0
Hrh1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494216,634,611 - 16,727,741 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366022,183,831 - 2,185,297 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366022,182,053 - 2,185,297 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HRH1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1367,209,127 - 67,411,170 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11367,209,261 - 67,411,174 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21374,579,748 - 74,631,302 (+)NCBISscrofa10.2Sscrofa10.2susScr3
HRH1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12247,187,156 - 47,298,761 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2247,295,011 - 47,296,471 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041119,219,292 - 119,336,578 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Hrh1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624943484,942 - 486,390 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624943483,230 - 505,678 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in HRH1
21 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 3p25.3-25.2(chr3:8581778-12015238)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051480]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051480]|See cases [RCV000051480] Chr3:8581778..12015238 [GRCh38]
Chr3:8623464..12056738 [GRCh37]
Chr3:8598464..12031738 [NCBI36]
Chr3:3p25.3-25.2		 pathogenic
GRCh38/hg38 3p25.3-25.2(chr3:10019780-12251358)x1 copy number loss See cases [RCV000051506] Chr3:10019780..12251358 [GRCh38]
Chr3:10061464..12292857 [GRCh37]
Chr3:10036464..12267857 [NCBI36]
Chr3:3p25.3-25.2		 pathogenic
GRCh38/hg38 3p26.3-22.2(chr3:52266-37148076)x3 copy number gain See cases [RCV000051097] Chr3:52266..37148076 [GRCh38]
Chr3:93949..37189567 [GRCh37]
Chr3:68949..37164571 [NCBI36]
Chr3:3p26.3-22.2		 pathogenic
GRCh38/hg38 3p26.3-24.3(chr3:52066-20280127)x3 copy number gain See cases [RCV000051690] Chr3:52066..20280127 [GRCh38]
Chr3:93749..20321619 [GRCh37]
Chr3:68749..20296623 [NCBI36]
Chr3:3p26.3-24.3		 pathogenic
GRCh38/hg38 3p26.3-24.1(chr3:52266-29248782)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051718]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051718]|See cases [RCV000051718] Chr3:52266..29248782 [GRCh38]
Chr3:93949..29290273 [GRCh37]
Chr3:68949..29265277 [NCBI36]
Chr3:3p26.3-24.1		 pathogenic
GRCh38/hg38 3p26.3-24.3(chr3:63843-19510600)x3 copy number gain See cases [RCV000051719] Chr3:63843..19510600 [GRCh38]
Chr3:105526..19552092 [GRCh37]
Chr3:80526..19527096 [NCBI36]
Chr3:3p26.3-24.3		 pathogenic
NM_001098211.1(HRH1):c.-36+9418C>T single nucleotide variant Lung cancer [RCV000092719] Chr3:11235477 [GRCh38]
Chr3:11277163 [GRCh37]
Chr3:3p25.3		 uncertain significance
GRCh38/hg38 3p26.1-25.3(chr3:8038727-11240931)x4 copy number gain See cases [RCV000135641] Chr3:8038727..11240931 [GRCh38]
Chr3:8080414..11282617 [GRCh37]
Chr3:8055414..11257617 [NCBI36]
Chr3:3p26.1-25.3		 likely pathogenic
GRCh38/hg38 3p25.3-25.2(chr3:9394874-11690612)x1 copy number loss See cases [RCV000137433] Chr3:9394874..11690612 [GRCh38]
Chr3:9436558..11732086 [GRCh37]
Chr3:9411558..11707086 [NCBI36]
Chr3:3p25.3-25.2		 pathogenic
GRCh38/hg38 3p26.1-25.2(chr3:7975734-12636917)x3 copy number gain See cases [RCV000137309] Chr3:7975734..12636917 [GRCh38]
Chr3:8017421..12678416 [GRCh37]
Chr3:7992421..12653416 [NCBI36]
Chr3:3p26.1-25.2		 likely pathogenic
GRCh38/hg38 3p26.3-25.2(chr3:32241-12681483)x1 copy number loss See cases [RCV000138143] Chr3:32241..12681483 [GRCh38]
Chr3:73914..12722982 [GRCh37]
Chr3:48914..12697982 [NCBI36]
Chr3:3p26.3-25.2		 pathogenic
GRCh38/hg38 3p26.3-24.1(chr3:32241-30064208)x3 copy number gain See cases [RCV000138004] Chr3:32241..30064208 [GRCh38]
Chr3:73914..30105699 [GRCh37]
Chr3:48914..30080703 [NCBI36]
Chr3:3p26.3-24.1		 pathogenic
GRCh38/hg38 3p26.3-24.3(chr3:32241-20334387)x3 copy number gain See cases [RCV000137941] Chr3:32241..20334387 [GRCh38]
Chr3:73914..20375879 [GRCh37]
Chr3:48914..20350883 [NCBI36]
Chr3:3p26.3-24.3		 pathogenic
GRCh38/hg38 3p26.3-25.3(chr3:32241-11379835)x1 copy number loss See cases [RCV000138376] Chr3:32241..11379835 [GRCh38]
Chr3:73914..11421309 [GRCh37]
Chr3:48914..11396309 [NCBI36]
Chr3:3p26.3-25.3		 pathogenic|likely benign
GRCh38/hg38 3p26.3-25.1(chr3:32241-13613818)x3 copy number gain See cases [RCV000138946] Chr3:32241..13613818 [GRCh38]
Chr3:73914..13655318 [GRCh37]
Chr3:48914..13630319 [NCBI36]
Chr3:3p26.3-25.1		 pathogenic
GRCh38/hg38 3p26.3-22.1(chr3:53308-41381521)x3 copy number gain See cases [RCV000141810] Chr3:53308..41381521 [GRCh38]
Chr3:94991..41423012 [GRCh37]
Chr3:69991..41398016 [NCBI36]
Chr3:3p26.3-22.1		 pathogenic
GRCh38/hg38 3p26.3-25.3(chr3:20213-11221602)x1 copy number loss See cases [RCV000141731] Chr3:20213..11221602 [GRCh38]
Chr3:61891..11263288 [GRCh37]
Chr3:36891..11238288 [NCBI36]
Chr3:3p26.3-25.3		 pathogenic
GRCh38/hg38 3p25.3(chr3:10220962-11165449)x1 copy number loss See cases [RCV000143098] Chr3:10220962..11165449 [GRCh38]
Chr3:10262646..11207135 [GRCh37]
Chr3:10237646..11182135 [NCBI36]
Chr3:3p25.3		 uncertain significance
GRCh38/hg38 3p26.1-25.1(chr3:7356110-14360442)x3 copy number gain See cases [RCV000143766] Chr3:7356110..14360442 [GRCh38]
Chr3:7397797..14401942 [GRCh37]
Chr3:7372797..14376946 [NCBI36]
Chr3:3p26.1-25.1		 pathogenic
GRCh37/hg19 3p25.3-25.2(chr3:8922160-12338637)x1 copy number loss See cases [RCV000240139] Chr3:8922160..12338637 [GRCh37]
Chr3:3p25.3-25.2		 pathogenic
GRCh37/hg19 3p26.3-24.2(chr3:61891-24432821)x3 copy number gain See cases [RCV000447247] Chr3:61891..24432821 [GRCh37]
Chr3:3p26.3-24.2		 pathogenic
GRCh37/hg19 3p26.3-22.2(chr3:61891-36710181)x3 copy number gain See cases [RCV000448528] Chr3:61891..36710181 [GRCh37]
Chr3:3p26.3-22.2		 pathogenic
GRCh37/hg19 3p26.3-22.3(chr3:61891-33958201)x3 copy number gain See cases [RCV000510429] Chr3:61891..33958201 [GRCh37]
Chr3:3p26.3-22.3		 pathogenic
GRCh37/hg19 3p26.3-22.2(chr3:61891-37459464)x3 copy number gain See cases [RCV000511463] Chr3:61891..37459464 [GRCh37]
Chr3:3p26.3-22.2		 pathogenic
GRCh37/hg19 3p26.3-25.2(chr3:61891-12575409)x1 copy number loss See cases [RCV000511155] Chr3:61891..12575409 [GRCh37]
Chr3:3p26.3-25.2		 pathogenic
GRCh37/hg19 3p26.3-q29(chr3:61892-197851986)x3 copy number gain See cases [RCV000511055] Chr3:61892..197851986 [GRCh37]
Chr3:3p26.3-q29		 pathogenic
GRCh37/hg19 3p26.3-q29(chr3:61892-197851986) copy number gain See cases [RCV000512358] Chr3:61892..197851986 [GRCh37]
Chr3:3p26.3-q29		 pathogenic
NM_001098212.2(HRH1):c.214G>A (p.Ala72Thr) single nucleotide variant not specified [RCV004309778] Chr3:11259251 [GRCh38]
Chr3:11300937 [GRCh37]
Chr3:3p25.3		 uncertain significance
GRCh37/hg19 3p26.3-24.3(chr3:1897972-19519085)x3 copy number gain not provided [RCV000682215] Chr3:1897972..19519085 [GRCh37]
Chr3:3p26.3-24.3		 pathogenic
GRCh37/hg19 3p26.1-24.3(chr3:5173870-16760262)x3 copy number gain not provided [RCV000682233] Chr3:5173870..16760262 [GRCh37]
Chr3:3p26.1-24.3		 pathogenic
GRCh37/hg19 3p26.3-q29(chr3:61495-197838262)x3 copy number gain not provided [RCV000742138] Chr3:61495..197838262 [GRCh37]
Chr3:3p26.3-q29		 pathogenic
GRCh37/hg19 3p26.3-q29(chr3:60174-197948027)x3 copy number gain not provided [RCV000742133] Chr3:60174..197948027 [GRCh37]
Chr3:3p26.3-q29		 pathogenic
NM_001098212.2(HRH1):c.57G>C (p.Lys19Asn) single nucleotide variant not provided [RCV000973020] Chr3:11259094 [GRCh38]
Chr3:11300780 [GRCh37]
Chr3:3p25.3		 benign
NM_001098212.2(HRH1):c.977G>A (p.Arg326Gln) single nucleotide variant not provided [RCV000879637] Chr3:11260014 [GRCh38]
Chr3:11301700 [GRCh37]
Chr3:3p25.3		 benign
NM_001098212.2(HRH1):c.42G>A (p.Met14Ile) single nucleotide variant not provided [RCV000908376] Chr3:11259079 [GRCh38]
Chr3:11300765 [GRCh37]
Chr3:3p25.3		 benign
NM_001098212.2(HRH1):c.1045G>C (p.Asp349His) single nucleotide variant not provided [RCV000953472] Chr3:11260082 [GRCh38]
Chr3:11301768 [GRCh37]
Chr3:3p25.3		 benign
Single allele duplication Neurodevelopmental disorder [RCV000787461] Chr3:9453917..12015126 [GRCh37]
Chr3:3p25.3-25.2		 uncertain significance
NM_001098212.2(HRH1):c.163G>A (p.Glu55Lys) single nucleotide variant not specified [RCV004271625] Chr3:11259200 [GRCh38]
Chr3:11300886 [GRCh37]
Chr3:3p25.3		 uncertain significance
GRCh37/hg19 3p26.3-22.2(chr3:61891-36710181) copy number gain not specified [RCV002053300] Chr3:61891..36710181 [GRCh37]
Chr3:3p26.3-22.2		 pathogenic
GRCh37/hg19 3p26.3-24.2(chr3:61891-24432821) copy number gain not specified [RCV002053299] Chr3:61891..24432821 [GRCh37]
Chr3:3p26.3-24.2		 pathogenic
GRCh37/hg19 3p25.3-25.2(chr3:10970972-12295919)x1 copy number loss Schizophrenia [RCV001825255] Chr3:10970972..12295919 [GRCh37]
Chr3:3p25.3-25.2		 not provided
GRCh37/hg19 3p25.3-25.2(chr3:10922740-12456978)x1 copy number loss not provided [RCV001827612] Chr3:10922740..12456978 [GRCh37]
Chr3:3p25.3-25.2		 pathogenic
NM_001098212.2(HRH1):c.1067A>G (p.Gln356Arg) single nucleotide variant not specified [RCV004289831] Chr3:11260104 [GRCh38]
Chr3:11301790 [GRCh37]
Chr3:3p25.3		 uncertain significance
GRCh37/hg19 3p26.3-25.3(chr3:61892-11679509)x1 copy number loss not provided [RCV002473616] Chr3:61892..11679509 [GRCh37]
Chr3:3p26.3-25.3		 pathogenic
GRCh37/hg19 3p25.3-25.2(chr3:10024917-11917048)x1 copy number loss not provided [RCV002472495] Chr3:10024917..11917048 [GRCh37]
Chr3:3p25.3-25.2		 pathogenic
NM_001098212.2(HRH1):c.581C>G (p.Thr194Ser) single nucleotide variant not specified [RCV004130577] Chr3:11259618 [GRCh38]
Chr3:11301304 [GRCh37]
Chr3:3p25.3		 uncertain significance
NM_001098212.2(HRH1):c.1337A>G (p.Asn446Ser) single nucleotide variant not specified [RCV004183446] Chr3:11260374 [GRCh38]
Chr3:11302060 [GRCh37]
Chr3:3p25.3		 uncertain significance
NM_001098212.2(HRH1):c.670C>T (p.Arg224Trp) single nucleotide variant not specified [RCV004254862] Chr3:11259707 [GRCh38]
Chr3:11301393 [GRCh37]
Chr3:3p25.3		 uncertain significance
GRCh37/hg19 3p25.3-25.2(chr3:10167260-12533766)x1 copy number loss See cases [RCV003329496] Chr3:10167260..12533766 [GRCh37]
Chr3:3p25.3-25.2		 pathogenic
GRCh37/hg19 3p26.3-24.1(chr3:310747-28297447)x3 copy number gain not provided [RCV003484107] Chr3:310747..28297447 [GRCh37]
Chr3:3p26.3-24.1		 pathogenic
NC_000003.12:g.11271763G>A single nucleotide variant not provided [RCV003433443] Chr3:11271763 [GRCh38]
Chr3:11313449 [GRCh37]
Chr3:3p25.3		 likely benign
GRCh37/hg19 3p26.1-25.3(chr3:6306331-11468530)x1 copy number loss not specified [RCV003986402] Chr3:6306331..11468530 [GRCh37]
Chr3:3p26.1-25.3		 pathogenic
GRCh37/hg19 3p26.3-22.3(chr3:61891-33946644)x3 copy number gain not specified [RCV003986437] Chr3:61891..33946644 [GRCh37]
Chr3:3p26.3-22.3		 pathogenic
GRCh37/hg19 3p26.3-22.3(chr3:60000-34461438)x3 copy number gain not provided [RCV004577500] Chr3:60000..34461438 [GRCh37]
Chr3:3p26.3-22.3		 pathogenic
NM_001098212.2(HRH1):c.242T>C (p.Met81Thr) single nucleotide variant not specified [RCV004402323] Chr3:11259279 [GRCh38]
Chr3:11300965 [GRCh37]
Chr3:3p25.3		 uncertain significance
NM_001098212.2(HRH1):c.65T>C (p.Met22Thr) single nucleotide variant not specified [RCV004402324] Chr3:11259102 [GRCh38]
Chr3:11300788 [GRCh37]
Chr3:3p25.3		 uncertain significance
NM_001098212.2(HRH1):c.983A>G (p.His328Arg) single nucleotide variant not specified [RCV004633120] Chr3:11260020 [GRCh38]
Chr3:11301706 [GRCh37]
Chr3:3p25.3		 uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2768
Count of miRNA genes:933
Interacting mature miRNAs:1089
Transcripts:ENST00000397056, ENST00000413416, ENST00000431010, ENST00000438284
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407161543GWAS810519_Hbody mass index QTL GWAS810519 (human)3e-08body mass indexbody mass index (BMI) (CMO:0000105)31115483011154831Human
407043396GWAS692372_Hbody mass index QTL GWAS692372 (human)8e-09body mass indexbody mass index (BMI) (CMO:0000105)31114300011143001Human
407002948GWAS651924_Hsystolic blood pressure QTL GWAS651924 (human)0.000002systolic blood pressuresystolic blood pressure (CMO:0000004)31124843611248437Human
407001540GWAS650516_Hpulse pressure measurement QTL GWAS650516 (human)2e-10pulse pressure measurementpulse pressure (CMO:0000292)31124843611248437Human
406927054GWAS576030_Happendicular lean mass QTL GWAS576030 (human)7e-09appendicular lean mass31123031911230320Human
407003921GWAS652897_Hsystolic blood pressure QTL GWAS652897 (human)3e-13systolic blood pressuresystolic blood pressure (CMO:0000004)31124843611248437Human
407332369GWAS981345_Hdiastolic blood pressure QTL GWAS981345 (human)4e-12diastolic blood pressurediastolic blood pressure (CMO:0000005)31124453411244535Human
2316345GLUCO224_HGlucose level QTL 224 (human)1.270.008Glucose level3121543441Human
406982040GWAS631016_Hheel bone mineral density QTL GWAS631016 (human)1e-29heel bone mineral densitybone mineral density (CMO:0001226)31125649511256496Human
407354395GWAS1003371_HBMI-adjusted hip circumference QTL GWAS1003371 (human)4e-10BMI-adjusted hip circumferencehip circumference (CMO:0000014)31123652511236526Human
407327271GWAS976247_Hblood urea nitrogen measurement QTL GWAS976247 (human)2e-11blood urea nitrogen measurementblood urea nitrogen level (CMO:0000049)31120727111207272Human
407358756GWAS1007732_HBMI-adjusted hip circumference QTL GWAS1007732 (human)6e-09BMI-adjusted hip circumferencehip circumference (CMO:0000014)31119303111193032Human
406922658GWAS571634_Hheel bone mineral density QTL GWAS571634 (human)8e-28heel bone mineral densitybone mineral density (CMO:0001226)31125902111259022Human
407000805GWAS649781_Hdiastolic blood pressure QTL GWAS649781 (human)0.000009diastolic blood pressurediastolic blood pressure (CMO:0000005)31124843611248437Human
407065832GWAS714808_Hbody mass index QTL GWAS714808 (human)4e-08body mass indexbody mass index (BMI) (CMO:0000105)31115483011154831Human
407324074GWAS973050_Hsystolic blood pressure QTL GWAS973050 (human)3e-09systolic blood pressuresystolic blood pressure (CMO:0000004)31119806211198063Human
407347433GWAS996409_Hinsomnia QTL GWAS996409 (human)3e-08insomnia31120784211207843Human
407347432GWAS996408_Hinsomnia QTL GWAS996408 (human)7e-09insomnia31119706511197066Human
407356150GWAS1005126_HBMI-adjusted hip circumference QTL GWAS1005126 (human)5e-11BMI-adjusted hip circumferencehip circumference (CMO:0000014)31123652511236526Human
407171120GWAS820096_Hbone measurement, fat body mass, lean body mass QTL GWAS820096 (human)2e-08body lean mass (VT:0010483)total body lean mass (CMO:0003950)31120243411202435Human
407026679GWAS675655_Hserum IgG glycosylation measurement QTL GWAS675655 (human)0.000008serum IgG glycosylation measurement31119109311191094Human
407002804GWAS651780_Hbody mass index QTL GWAS651780 (human)1e-14body mass indexbody mass index (BMI) (CMO:0000105)31123833111238332Human
407248892GWAS897868_HLewy body dementia QTL GWAS897868 (human)0.0000002Lewy body dementia31118523611185237Human
407145466GWAS794442_Hmortality QTL GWAS794442 (human)0.0000007mortalityratio of deaths to total study population during a period of time (CMO:0001023)31117600511176006Human
407065469GWAS714445_Hheel bone mineral density QTL GWAS714445 (human)6e-24heel bone mineral densitybone mineral density (CMO:0001226)31126124711261248Human

Markers in Region
D3S4194  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37311,302,232 - 11,302,393UniSTSGRCh37
Build 36311,277,232 - 11,277,393RGDNCBI36
Celera311,237,656 - 11,237,817RGD
Cytogenetic Map3p25UniSTS
HuRef311,236,498 - 11,236,659UniSTS
Stanford-G3 RH Map3485.0UniSTS
NCBI RH Map3132.9UniSTS
GeneMap99-G3 RH Map3485.0UniSTS
RH36646  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh372113,289,874 - 113,289,930UniSTSGRCh37
GRCh37311,302,007 - 11,302,794UniSTSGRCh37
Build 362113,006,345 - 113,006,401RGDNCBI36
Celera2106,675,415 - 106,675,471RGD
Celera311,237,431 - 11,238,218UniSTS
Cytogenetic Map2q13UniSTS
Cytogenetic Map3p25UniSTS
HuRef2105,744,375 - 105,744,431UniSTS
D3S3461  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37311,267,043 - 11,267,258UniSTSGRCh37
Build 36311,242,043 - 11,242,258RGDNCBI36
Celera311,202,483 - 11,202,698RGD
Cytogenetic Map3p25UniSTS
HuRef311,201,342 - 11,201,557UniSTS
SHGC-148056  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37311,231,649 - 11,231,748UniSTSGRCh37
Build 36311,206,649 - 11,206,748RGDNCBI36
Celera311,167,089 - 11,167,188RGD
Cytogenetic Map3p25UniSTS
HuRef311,165,948 - 11,166,047UniSTS
TNG Radiation Hybrid Map36806.0UniSTS
SHGC-148108  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37311,286,137 - 11,286,417UniSTSGRCh37
Build 36311,261,137 - 11,261,417RGDNCBI36
Celera311,221,562 - 11,221,842RGD
Cytogenetic Map3p25UniSTS
HuRef311,220,414 - 11,220,694UniSTS
TNG Radiation Hybrid Map36831.0UniSTS
SHGC-132075  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37311,302,218 - 11,302,416UniSTSGRCh37
Build 36311,277,218 - 11,277,416RGDNCBI36
Celera311,237,642 - 11,237,840RGD
Cytogenetic Map3p25UniSTS
HuRef311,236,484 - 11,236,682UniSTS
TNG Radiation Hybrid Map36838.0UniSTS
HRH1_1003  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37311,301,672 - 11,302,549UniSTSGRCh37
Build 36311,276,672 - 11,277,549RGDNCBI36
Celera311,237,096 - 11,237,973RGD
HuRef311,235,938 - 11,236,815UniSTS
WI-15608  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37311,304,779 - 11,304,928UniSTSGRCh37
Build 36311,279,779 - 11,279,928RGDNCBI36
Celera311,240,203 - 11,240,352RGD
Cytogenetic Map3p25UniSTS
HuRef311,239,045 - 11,239,194UniSTS
GeneMap99-GB4 RH Map352.69UniSTS
Whitehead-RH Map358.6UniSTS
D3S3145  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37311,279,033 - 11,279,131UniSTSGRCh37
Build 36311,254,033 - 11,254,131RGDNCBI36
Celera311,214,472 - 11,214,570RGD
Cytogenetic Map3p25UniSTS
HuRef311,213,330 - 11,213,428UniSTS
D3S3138  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37311,267,069 - 11,267,234UniSTSGRCh37
Build 36311,242,069 - 11,242,234RGDNCBI36
Celera311,202,509 - 11,202,674RGD
Cytogenetic Map3p25UniSTS
HuRef311,201,368 - 11,201,533UniSTS
SHGC-76733  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37311,301,800 - 11,301,924UniSTSGRCh37
Build 36311,276,800 - 11,276,924RGDNCBI36
Celera311,237,224 - 11,237,348RGD
Cytogenetic Map3p25UniSTS
HuRef311,236,066 - 11,236,190UniSTS
TNG Radiation Hybrid Map36838.0UniSTS
GeneMap99-GB4 RH Map357.42UniSTS
NCBI RH Map3143.8UniSTS
RH79740  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map7q11.23UniSTS
Cytogenetic Map3p25UniSTS
Cytogenetic Map12q13UniSTS
Cytogenetic Map17q21.1-q21.3UniSTS
Cytogenetic Map9q31.3UniSTS
Cytogenetic Map12q24UniSTS
D10S275  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map21q21.3UniSTS
Cytogenetic Map17q24.2UniSTS
Cytogenetic Map1q32.1UniSTS
Cytogenetic Map13q12.13UniSTS
Cytogenetic Map5q31.2UniSTS
Cytogenetic Map10q11.22UniSTS
Cytogenetic Map22q13.33UniSTS
Cytogenetic Map2p25.1UniSTS
Cytogenetic Map4q12UniSTS
Cytogenetic Map19p13.12UniSTS
Cytogenetic Map7p13UniSTS
Cytogenetic Map2q11.2UniSTS
Cytogenetic Map17q25.1UniSTS
Cytogenetic Map8q24.13UniSTS
Cytogenetic Map19q13.12UniSTS
Cytogenetic Map16q22.2UniSTS
Cytogenetic Map16q11.2UniSTS
Cytogenetic Map14q24.3UniSTS
Cytogenetic Map6q22UniSTS
Cytogenetic Map2q33.1UniSTS
Cytogenetic Map20q11UniSTS
Cytogenetic Map5q31.1UniSTS
Cytogenetic Map4q32.3UniSTS
Cytogenetic Map3p22.1UniSTS
Cytogenetic Map1p35.2UniSTS
Cytogenetic Map19q13.3UniSTS
Cytogenetic Map14q24UniSTS
Cytogenetic Map14q22-q24UniSTS
Cytogenetic Map1p21.2UniSTS
Cytogenetic Map12q24.31UniSTS
Cytogenetic Map14q11.2UniSTS
Cytogenetic Map20q13.31UniSTS
Cytogenetic Map19p13.3UniSTS
Cytogenetic Map5q35.3UniSTS
Cytogenetic Map1p36.13UniSTS
Cytogenetic Map4q35.1UniSTS
Cytogenetic MapXp11.3UniSTS
Cytogenetic Map16q24UniSTS
Cytogenetic Map16p13.3UniSTS
Cytogenetic Map16q12.1UniSTS
Cytogenetic Map1p36.1UniSTS
Cytogenetic Map22q12.3UniSTS
Cytogenetic Map6p21.33UniSTS
Cytogenetic Map10p11UniSTS
Cytogenetic Map1p13.1UniSTS
Cytogenetic Map7q22.1UniSTS
Cytogenetic Map19q13.32UniSTS
Cytogenetic Map7p22.2UniSTS
Cytogenetic MapXq22.1UniSTS
Cytogenetic Map16q21UniSTS
Cytogenetic Map1p36.31UniSTS
Cytogenetic Map3q12.3UniSTS
Cytogenetic Map6q24UniSTS
Cytogenetic Map3p21.31UniSTS
Cytogenetic Map9q13-q21UniSTS
Cytogenetic Map3p25UniSTS
Cytogenetic Map6p21.3UniSTS
Cytogenetic Map7q22.3UniSTS
Cytogenetic Map9q22UniSTS
Cytogenetic Map12q13.3UniSTS
Cytogenetic Map1q21-q23UniSTS
Cytogenetic Map5q23.3UniSTS
Cytogenetic Map20q13UniSTS
Cytogenetic Map1p35.1UniSTS
Cytogenetic Map1p32.3UniSTS
Cytogenetic Map21q22.13UniSTS
Cytogenetic Map19q13.2UniSTS
Cytogenetic Map19q13.43UniSTS
Cytogenetic Map22q13.2UniSTS
Cytogenetic MapXp22.2-p22.1UniSTS
Cytogenetic Map7q11.23UniSTS
Cytogenetic Map10q26.13UniSTS
Cytogenetic Map2q33.2UniSTS
Cytogenetic Map8q24.3UniSTS
Cytogenetic Map20pter-q11.23UniSTS
Cytogenetic Map4p16.3UniSTS
Cytogenetic Map10p12.1UniSTS
Cytogenetic Map10p12.3UniSTS
Cytogenetic Map12p13.3UniSTS
Cytogenetic Map3q27UniSTS
Cytogenetic Map17p13.2UniSTS
Cytogenetic Map1p34.2UniSTS
Cytogenetic Map21q22.3UniSTS
Cytogenetic Map2q14.3UniSTS
Cytogenetic Map3p14.1UniSTS
Cytogenetic Map3q26.3UniSTS
Cytogenetic Map1q21.3UniSTS
Cytogenetic Map14q32.31UniSTS
Cytogenetic Map17q22UniSTS
Cytogenetic Map2p16.1UniSTS
Cytogenetic Map3q27.1UniSTS
Cytogenetic Map22q13UniSTS
Cytogenetic Map11q22.3UniSTS
Cytogenetic Map9q21.13UniSTS
Cytogenetic Map16p11.2UniSTS
Cytogenetic Map10q24.31UniSTS
Cytogenetic Map9q22.31UniSTS
Cytogenetic Map15q21UniSTS
Cytogenetic Map17p13.1UniSTS
Cytogenetic Map15q25.2UniSTS
Cytogenetic Map12p12UniSTS
Cytogenetic Map3q13.31UniSTS
Cytogenetic Map5q23.2UniSTS
Cytogenetic Map22q11.2UniSTS
Cytogenetic Map1q24-q25.3UniSTS
Cytogenetic Map7p11UniSTS
Cytogenetic Map2q32.1UniSTS
Cytogenetic Map17q23.3UniSTS
Cytogenetic MapXq13-q21UniSTS
Cytogenetic Map6p24.3UniSTS
Cytogenetic Map11p15.4UniSTS
Cytogenetic Map1q21.2-q21.3UniSTS
Cytogenetic Map6q25.2-q27UniSTS
Cytogenetic Map11q23UniSTS
Cytogenetic Map9q34UniSTS
Cytogenetic Map12q24.32UniSTS
Cytogenetic MapXq13.1UniSTS
Cytogenetic Map10q11.21UniSTS
Cytogenetic Map14q32.3UniSTS
Cytogenetic Map13q12-q14UniSTS
Cytogenetic MapXp11.23UniSTS
Cytogenetic Map22q11.21UniSTS
Cytogenetic Map1p36.11UniSTS
Cytogenetic Map2p11.2UniSTS
Cytogenetic Map1q21.2UniSTS
Cytogenetic Map14q23.1UniSTS
Cytogenetic Map20q13.3UniSTS
Cytogenetic Map2q24.1UniSTS
Cytogenetic Map10q25.3UniSTS
Cytogenetic Map14q31UniSTS
Cytogenetic Map15q25.1UniSTS
Cytogenetic Map15q26.1UniSTS
Cytogenetic Map8p21.1UniSTS
Cytogenetic Map2p15UniSTS
Cytogenetic Map17q23.2UniSTS
Cytogenetic Map11p14.3UniSTS
Cytogenetic Map9q33.3UniSTS
Cytogenetic Map1p13.3UniSTS
Cytogenetic Map4q13UniSTS
Cytogenetic MapXq12UniSTS
Cytogenetic Map3p25.3UniSTS
Cytogenetic Map1p34.3UniSTS
Cytogenetic Map19q13.42UniSTS
Cytogenetic Map16q24.3UniSTS
Cytogenetic MapXp11.4UniSTS
Cytogenetic Map7q34UniSTS
Cytogenetic Map2p25.3UniSTS
Cytogenetic Map1q41UniSTS
Cytogenetic Map5q14.1UniSTS
Cytogenetic Map15q15.2UniSTS
Cytogenetic Map12p11.21UniSTS
Cytogenetic Map5p13.1UniSTS
Cytogenetic Map7q31.3UniSTS
Cytogenetic Map2q35UniSTS
Cytogenetic Map16q23.1UniSTS
Cytogenetic Map12q13.13UniSTS
Cytogenetic Map1p21UniSTS
Cytogenetic MapXq24UniSTS
Cytogenetic Map7p14.2UniSTS
Cytogenetic Map6q24.3UniSTS
Cytogenetic Map22q13.31UniSTS
Cytogenetic Map9p24.3UniSTS
Cytogenetic Map6q12-q13UniSTS
Cytogenetic Map19q13UniSTS
Cytogenetic Map9q31-q33UniSTS
Cytogenetic Map9q34.1UniSTS
Cytogenetic Map17p11.2UniSTS
Cytogenetic Map14q32UniSTS
Cytogenetic Map3p14.3UniSTS
Cytogenetic Map8p11.21UniSTS
Cytogenetic Map16p12.3UniSTS
Cytogenetic Map9q31.3UniSTS
Cytogenetic Map9p13.2UniSTS
Cytogenetic Map5q13.2UniSTS
Cytogenetic Map18q23UniSTS
Cytogenetic Map8p22UniSTS
Cytogenetic Map17p13UniSTS
Cytogenetic Map19p12UniSTS
Cytogenetic Map8p21.2UniSTS
Cytogenetic Map12q13.11UniSTS
Cytogenetic Map1q32.3UniSTS
Cytogenetic Map1p33UniSTS
Cytogenetic Map19q13.31UniSTS
Cytogenetic Map6p21UniSTS
Cytogenetic Map17q21.31UniSTS
Cytogenetic Map3p22.2UniSTS
Cytogenetic Map17q12UniSTS
Cytogenetic MapXp21.1UniSTS
Cytogenetic Map12q13UniSTS
Cytogenetic Map11q13.2UniSTS
Cytogenetic Map11p15.1UniSTS
Cytogenetic Map1q43UniSTS
Cytogenetic Map19p13.2UniSTS
Cytogenetic Map15q21.2UniSTS
Cytogenetic Map9q22.2UniSTS
Cytogenetic MapXp22UniSTS
Cytogenetic Map13q14UniSTS
Cytogenetic Map3p21.3UniSTS
Cytogenetic Map7q22UniSTS
Cytogenetic Map2p22UniSTS
Cytogenetic Map11q13.1UniSTS
Cytogenetic Map3p25.2UniSTS
Cytogenetic Map14q22.3UniSTS
Cytogenetic Map2p14UniSTS


Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
1204 2437 2788 2238 4932 1711 2324 5 610 1404 452 2245 6753 5934 49 3715 852 1739 1602 174 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_000861 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001098211 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001098212 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001098213 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB041380 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC083855 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF026261 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF420434 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ000742 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK289412 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK292157 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK312879 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY136743 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC060802 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BM905371 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BP366267 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471055 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068275 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D14436 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D28481 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DA372691 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DB073635 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DC300229 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U37761 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X76786 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Z34897 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENST00000397056   ⟹   ENSP00000380247
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl311,252,699 - 11,263,557 (+)Ensembl
Ensembl Acc Id: ENST00000413416   ⟹   ENSP00000392383
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl311,226,031 - 11,259,075 (+)Ensembl
Ensembl Acc Id: ENST00000431010   ⟹   ENSP00000397028
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl311,154,493 - 11,263,557 (+)Ensembl
Ensembl Acc Id: ENST00000438284   ⟹   ENSP00000406705
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl311,137,093 - 11,260,775 (+)Ensembl
RefSeq Acc Id: NM_000861   ⟹   NP_000852
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38311,252,699 - 11,263,253 (+)NCBI
GRCh37311,178,779 - 11,304,939 (+)ENTREZGENE
Build 36311,269,385 - 11,279,939 (+)NCBI Archive
HuRef311,113,586 - 11,239,205 (+)ENTREZGENE
CHM1_1311,244,444 - 11,254,995 (+)NCBI
T2T-CHM13v2.0311,247,626 - 11,258,180 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001098211   ⟹   NP_001091681
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38311,225,981 - 11,263,557 (+)NCBI
GRCh37311,178,779 - 11,304,939 (+)ENTREZGENE
Build 36311,242,669 - 11,279,939 (+)NCBI Archive
HuRef311,113,586 - 11,239,205 (+)ENTREZGENE
CHM1_1311,217,724 - 11,254,995 (+)NCBI
T2T-CHM13v2.0311,220,934 - 11,258,484 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001098212   ⟹   NP_001091682
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38311,154,493 - 11,263,557 (+)NCBI
GRCh37311,178,779 - 11,304,939 (+)ENTREZGENE
Build 36311,171,214 - 11,279,939 (+)NCBI Archive
HuRef311,113,586 - 11,239,205 (+)ENTREZGENE
CHM1_1311,146,269 - 11,254,995 (+)NCBI
T2T-CHM13v2.0311,149,432 - 11,258,484 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001098213   ⟹   NP_001091683
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38311,137,238 - 11,263,557 (+)NCBI
GRCh37311,178,779 - 11,304,939 (+)ENTREZGENE
Build 36311,153,779 - 11,279,939 (+)NCBI Archive
HuRef311,113,586 - 11,239,205 (+)ENTREZGENE
CHM1_1311,128,810 - 11,254,995 (+)NCBI
T2T-CHM13v2.0311,131,678 - 11,258,484 (+)NCBI
Sequence:
RefSeq Acc Id: NP_001091683   ⟸   NM_001098213
- UniProtKB: A8K047 (UniProtKB/Swiss-Prot),   Q6P9E5 (UniProtKB/Swiss-Prot),   P35367 (UniProtKB/Swiss-Prot),   A8K7Z2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001091681   ⟸   NM_001098211
- UniProtKB: A8K047 (UniProtKB/Swiss-Prot),   Q6P9E5 (UniProtKB/Swiss-Prot),   P35367 (UniProtKB/Swiss-Prot),   A8K7Z2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_000852   ⟸   NM_000861
- UniProtKB: A8K047 (UniProtKB/Swiss-Prot),   Q6P9E5 (UniProtKB/Swiss-Prot),   P35367 (UniProtKB/Swiss-Prot),   A8K7Z2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001091682   ⟸   NM_001098212
- UniProtKB: A8K047 (UniProtKB/Swiss-Prot),   Q6P9E5 (UniProtKB/Swiss-Prot),   P35367 (UniProtKB/Swiss-Prot),   A8K7Z2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSP00000406705   ⟸   ENST00000438284
Ensembl Acc Id: ENSP00000392383   ⟸   ENST00000413416
Ensembl Acc Id: ENSP00000397028   ⟸   ENST00000431010
Ensembl Acc Id: ENSP00000380247   ⟸   ENST00000397056
Protein Domains
G-protein coupled receptors family 1 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P35367-F1-model_v2 AlphaFold P35367 1-487 view protein structure

Promoters
RGD ID:6801133
Promoter ID:HG_KWN:43731
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:HeLa_S3
Transcripts:NM_001098213
Position:
Human AssemblyChrPosition (strand)Source
Build 36311,153,796 - 11,154,296 (+)MPROMDB
RGD ID:6863584
Promoter ID:EPDNEW_H4957
Type:initiation region
Name:HRH1_1
Description:histamine receptor H1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H4958  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38311,154,588 - 11,154,648EPDNEW
RGD ID:6863586
Promoter ID:EPDNEW_H4958
Type:single initiation site
Name:HRH1_2
Description:histamine receptor H1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H4957  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38311,170,642 - 11,170,702EPDNEW
RGD ID:6801132
Promoter ID:HG_KWN:43732
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:HeLa_S3
Transcripts:NM_001098212
Position:
Human AssemblyChrPosition (strand)Source
Build 36311,171,116 - 11,171,616 (+)MPROMDB
RGD ID:6801130
Promoter ID:HG_KWN:43733
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:HeLa_S3,   NB4
Transcripts:NM_001098211,   OTTHUMT00000339091
Position:
Human AssemblyChrPosition (strand)Source
Build 36311,242,476 - 11,242,976 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:5182 AgrOrtholog
COSMIC HRH1 COSMIC
Ensembl Genes ENSG00000196639 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000397056 ENTREZGENE
  ENST00000397056.1 UniProtKB/Swiss-Prot
  ENST00000413416.1 UniProtKB/TrEMBL
  ENST00000431010 ENTREZGENE
  ENST00000431010.3 UniProtKB/Swiss-Prot
  ENST00000438284 ENTREZGENE
  ENST00000438284.2 UniProtKB/Swiss-Prot
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000196639 GTEx
HGNC ID HGNC:5182 ENTREZGENE
Human Proteome Map HRH1 Human Proteome Map
InterPro GPCR_Rhodpsn UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Histamine_H1_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:3269 UniProtKB/Swiss-Prot
NCBI Gene 3269 ENTREZGENE
OMIM 600167 OMIM
PANTHER 5-HYDROXYTRYPTAMINE RECEPTOR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HISTAMINE H1 RECEPTOR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam 7tm_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB HRH1 RGD, PharmGKB
PRINTS GPCRRHODOPSN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HISTAMINEH1R UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART 7TM_GPCR_Srsx UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A8K047 ENTREZGENE
  A8K7Z2 ENTREZGENE, UniProtKB/TrEMBL
  C9J2E6_HUMAN UniProtKB/TrEMBL
  HRH1_HUMAN UniProtKB/Swiss-Prot, ENTREZGENE
  Q6P9E5 ENTREZGENE
UniProt Secondary A8K047 UniProtKB/Swiss-Prot
  Q6P9E5 UniProtKB/Swiss-Prot