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Gene: CHMP4C (charged multivesicular body protein 4C) Homo sapiens
Symbol: CHMP4C
Name: charged multivesicular body protein 4C
Description: Exhibits protein homodimerization activity. Involved in several processes, including midbody abscission; regulation of cell cycle process; and ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway. Localizes to the Flemming body.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: chromatin modifying protein 4C; chromatin-modifying protein 4c; hSnf7-3; hVps32-3; MGC22825; Shax3; SNF7 homolog associated with Alix 3; Snf7 homologue associated with Alix 3; SNF7-3; vacuolar protein sorting-associated protein 32-3; vps32-3; VPS32C
Mus musculus (house mouse) : Chmp4c (charged multivesicular body protein 4C)  MGI  Alliance
Rattus norvegicus (Norway rat) : Chmp4c (charged multivesicular body protein 4C)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Chmp4c (charged multivesicular body protein 4C)
Pan paniscus (bonobo/pygmy chimpanzee) : CHMP4C (charged multivesicular body protein 4C)
Canis lupus familiaris (dog) : CHMP4C (charged multivesicular body protein 4C)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Chmp4c (charged multivesicular body protein 4C)
Sus scrofa (pig) : CHMP4C (charged multivesicular body protein 4C)
Chlorocebus sabaeus (African green monkey) : CHMP4C (charged multivesicular body protein 4C)
Heterocephalus glaber (naked mole-rat) : Chmp4c (charged multivesicular body protein 4C)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl881,732,448 - 81,759,515 (+)Ensembl
GRCh38881,732,448 - 81,759,515 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37882,644,688 - 82,671,750 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36882,807,243 - 82,834,305 (+)NCBINCBI36hg18NCBI36
Celera878,649,178 - 78,676,231 (+)NCBI
Cytogenetic Map8q21.13NCBI
HuRef878,134,628 - 78,161,684 (+)NCBIHuRef
CHM1_1882,696,279 - 82,723,341 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on CHMP4C
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1606751
Created: 2007-04-29
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.