PIK3CG (phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma) - Rat Genome Database

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Gene: PIK3CG (phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma) Homo sapiens
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Symbol: PIK3CG
Name: phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
RGD ID: 1315103
HGNC Page HGNC
Description: Exhibits ephrin receptor binding activity; identical protein binding activity; and phosphatidylinositol 3-kinase activity. Involved in several processes, including phosphatidylinositol 3-kinase signaling; positive regulation of intracellular signal transduction; and sphingosine-1-phosphate receptor signaling pathway. Localizes to cytosol; phosphatidylinositol 3-kinase complex, class IB; and plasma membrane. Implicated in autistic disorder and swine influenza. Biomarker of pancreatic ductal adenocarcinoma.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 1-phosphatidylinositol 3-kinase; p110-gamma; p110gamma; p120-PI3K; phosphatidylinositol 3 kinase gamma, p110 gamma; phosphatidylinositol 3-kinase catalytic 110-kD gamma; phosphatidylinositol 3-kinase, catalytic, gamma polypeptide; phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit gamma; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform; phosphatidylinositol-4,5-bisphosphate 3-kinase 110 kDa catalytic subunit gamma; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform; phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma; phosphoinositide-3-kinase catalytic gamma polypeptide; phosphoinositide-3-kinase gamma catalytic subunit; phosphoinositide-3-kinase, catalytic, gamma polypeptide; PI3-kinase subunit gamma; PI3CG; PI3K; PI3K-gamma; PI3Kgamma; PIK3; ptdIns-3-kinase subunit gamma; ptdIns-3-kinase subunit p110-gamma; serine/threonine protein kinase PIK3CG
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl7106,865,278 - 106,908,980 (+)EnsemblGRCh38hg38GRCh38
GRCh387106,865,282 - 106,908,980 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh377106,505,727 - 106,549,425 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 367106,293,160 - 106,334,828 (+)NCBINCBI36hg18NCBI36
Build 347106,099,874 - 106,141,543NCBI
Celera7101,311,222 - 101,352,879 (+)NCBI
Cytogenetic Map7q22.3NCBI
HuRef7100,864,687 - 100,906,376 (+)NCBIHuRef
CHM1_17106,439,249 - 106,482,951 (+)NCBICHM1_1
CRA_TCAGchr7v27105,867,019 - 105,908,676 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
adaptive immune response  (TAS)
angiogenesis  (IEA)
cell migration  (IBA)
cellular response to cAMP  (IEA,ISO)
dendritic cell chemotaxis  (TAS)
endocytosis  (IEA)
G protein-coupled receptor signaling pathway  (IDA)
hepatocyte apoptotic process  (IEA,ISO)
inflammatory response  (TAS)
innate immune response  (TAS)
mast cell degranulation  (TAS)
natural killer cell chemotaxis  (TAS)
negative regulation of cardiac muscle contraction  (TAS)
negative regulation of fibroblast apoptotic process  (IEA,ISO)
negative regulation of triglyceride catabolic process  (IEA,ISO)
neutrophil chemotaxis  (TAS)
neutrophil extravasation  (TAS)
phosphatidylinositol 3-kinase signaling  (IBA,IDA,IMP,TAS)
phosphatidylinositol biosynthetic process  (TAS)
phosphatidylinositol phosphate biosynthetic process  (IBA,IEA,ISO)
phosphatidylinositol-3-phosphate biosynthetic process  (IBA)
phosphatidylinositol-mediated signaling  (IBA,IEA)
phosphorylation  (IDA,IEA)
platelet activation  (TAS)
platelet aggregation  (TAS)
positive regulation of acute inflammatory response  (IEA,ISO)
positive regulation of catalytic activity  (ISO)
positive regulation of cytokine production  (TAS)
positive regulation of cytosolic calcium ion concentration  (IEA,ISO)
positive regulation of endothelial cell migration  (IMP)
positive regulation of MAP kinase activity  (IDA)
positive regulation of phosphatidylinositol 3-kinase signaling  (TAS)
positive regulation of protein kinase B signaling  (IDA)
positive regulation of Rac protein signal transduction  (IMP)
protein phosphorylation  (IEA,ISO)
regulation of calcium ion transmembrane transport  (IEA,ISO)
regulation of cell adhesion mediated by integrin  (TAS)
regulation of protein phosphorylation  (ISO)
respiratory burst involved in defense response  (TAS)
secretory granule localization  (IEA,ISO)
sphingosine-1-phosphate receptor signaling pathway  (IMP)
T cell activation  (TAS)
T cell chemotaxis  (TAS)
T cell proliferation  (TAS)

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

References - curated
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2. Becattini B, etal., Proc Natl Acad Sci U S A. 2011 Oct 18;108(42):E854-63. Epub 2011 Sep 26.
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6. Dutra RC, etal., Br J Pharmacol. 2011 May;163(2):358-74. doi: 10.1111/j.1476-5381.2011.01226.x.
7. Edling CE, etal., Clin Cancer Res. 2010 Oct 15;16(20):4928-37. doi: 10.1158/1078-0432.CCR-10-1210. Epub 2010 Sep 28.
8. Ferrandi C, etal., J Pharmacol Exp Ther. 2007 Sep;322(3):923-30. Epub 2007 May 25.
9. Garcia CC, etal., Front Immunol. 2018 May 15;9:975. doi: 10.3389/fimmu.2018.00975. eCollection 2018.
10. GOA_HUMAN data from the GO Consortium
11. Gonzalez-Garcia A, etal., Gastroenterology. 2010 Apr;138(4):1374-83. Epub 2009 Dec 11.
12. Gruen M, etal., BMC Musculoskelet Disord. 2010 Apr 7;11:63.
13. Haubner BJ, etal., PLoS One. 2010 Feb 22;5(2):e9350.
14. Huang Y, etal., J Cell Physiol. 2018 Oct;233(10):6693-6704. doi: 10.1002/jcp.26469. Epub 2018 Apr 25.
15. Jin R, etal., Stroke. 2011 Jul;42(7):2033-44. Epub 2011 May 5.
16. Kim DI, etal., J Clin Immunol. 2012 Apr;32(2):340-51. Epub 2011 Dec 24.
17. Kobayashi T and Puro DG, Invest Ophthalmol Vis Sci. 2007 May;48(5):2350-5.
18. Lacerda-Queiroz N, etal., PLoS One. 2015 Mar 16;10(3):e0119633. doi: 10.1371/journal.pone.0119633. eCollection 2015.
19. Lionetti V, etal., Crit Care Med. 2006 Jan;34(1):134-41.
20. Lu JM, etal., Exp Eye Res. 2020 Jan;190:107886. doi: 10.1016/j.exer.2019.107886. Epub 2019 Nov 21.
21. Martin D, etal., Cancer Cell. 2011 Jun 14;19(6):805-13. doi: 10.1016/j.ccr.2011.05.005.
22. Martin EL, etal., Am J Respir Crit Care Med. 2010 Sep 15;182(6):762-73. Epub 2010 May 27.
23. Maus UA, etal., Am J Respir Crit Care Med. 2007 May 1;175(9):958-66. doi: 10.1164/rccm.200610-1533OC. Epub 2007 Feb 22.
24. Passos GF, etal., Brain Behav Immun. 2010 Mar;24(3):493-501. Epub 2009 Dec 16.
25. Perrino C, etal., J Am Coll Cardiol. 2005 Jun 7;45(11):1862-70.
26. Pipeline to import KEGG annotations from KEGG into RGD
27. Pipeline to import Pathway Interaction Database annotations from NCI into RGD
28. Pipeline to import SMPDB annotations from SMPDB into RGD
29. Randis TM, etal., Eur J Immunol. 2008 May;38(5):1215-24.
30. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
31. RGD automated import pipeline for gene-chemical interactions
32. Rodrigues DH, etal., J Neuroimmunol. 2010 May;222(1-2):90-4. Epub 2010 Mar 19.
33. Schneider C, etal., J Leukoc Biol. 2017 Feb;101(2):367-376. doi: 10.1189/jlb.4HI0316-157R. Epub 2016 Jul 28.
34. Serajee FJ, etal., J Med Genet. 2003 Nov;40(11):e119.
35. Silva MC, etal., Nat Commun. 2018 Apr 17;9(1):1513. doi: 10.1038/s41467-018-03986-3.
36. Siragusa M, etal., Circ Res. 2010 Mar 5;106(4):757-68. Epub 2010 Jan 7.
37. Song LF, etal., Sichuan Da Xue Xue Bao Yi Xue Ban. 2011 Jul;42(4):471-4.
38. Sun X, etal., J Immunol. 2013 Jan 1;190(1):357-65. doi: 10.4049/jimmunol.1201825. Epub 2012 Nov 23.
39. Thomas M, etal., Immunology. 2009 Mar;126(3):413-22. Epub 2008 Aug 27.
40. Tosaka S, etal., J Anesth. 2007;21(2):176-80. Epub 2007 May 30.
41. van Dop WA, etal., Immunol Lett. 2010 Jun 15;131(1):33-9. doi: 10.1016/j.imlet.2010.03.008. Epub 2010 Mar 27.
42. Xu H, etal., J Immunol. 2010 Feb 1;184(3):1492-8. doi: 10.4049/jimmunol.0902660. Epub 2009 Dec 18.
43. Yuan G, etal., Endocrinology. 2007 May;148(5):2016-26. Epub 2007 Feb 1.
44. Yum HK, etal., J Immunol. 2001 Dec 1;167(11):6601-8. doi: 10.4049/jimmunol.167.11.6601.
Additional References at PubMed
PMID:7520444   PMID:7606002   PMID:7624799   PMID:7721825   PMID:8313897   PMID:8636073   PMID:8798481   PMID:9113989   PMID:9247029   PMID:9341793   PMID:9394803   PMID:9446654  
PMID:9446795   PMID:9507010   PMID:9708406   PMID:9808187   PMID:9915850   PMID:10208934   PMID:10318860   PMID:10358071   PMID:10386953   PMID:10488142   PMID:10542052   PMID:10571082  
PMID:10579793   PMID:10580505   PMID:10816567   PMID:10871282   PMID:10972292   PMID:10985305   PMID:11136978   PMID:11154208   PMID:11156964   PMID:11238738   PMID:11259422   PMID:11277933  
PMID:11289809   PMID:11416136   PMID:11453982   PMID:11577104   PMID:11756194   PMID:11756422   PMID:11861293   PMID:11994280   PMID:12077252   PMID:12115604   PMID:12163475   PMID:12242282  
PMID:12435806   PMID:12464013   PMID:12473596   PMID:12477932   PMID:12502714   PMID:12507995   PMID:12526811   PMID:12529294   PMID:12545160   PMID:12551992   PMID:12584329   PMID:12606772  
PMID:12690205   PMID:12757856   PMID:12774123   PMID:12853948   PMID:12960231   PMID:13130092   PMID:14583609   PMID:14602571   PMID:14605879   PMID:14622970   PMID:15001544   PMID:15044087  
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PMID:17302605   PMID:17303701   PMID:17375124   PMID:17410437   PMID:17459875   PMID:17497700   PMID:17515959   PMID:17551921   PMID:17595318   PMID:17632570   PMID:17646933   PMID:17658464  
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PMID:18515365   PMID:18520805   PMID:18535744   PMID:18546844   PMID:18552129   PMID:18558630   PMID:18587247   PMID:18593948   PMID:18603327   PMID:18615538   PMID:18625725   PMID:18632611  
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PMID:19062713   PMID:19075988   PMID:19078992   PMID:19079138   PMID:19086053   PMID:19103290   PMID:19147653   PMID:19152965   PMID:19179443   PMID:19192227   PMID:19211028   PMID:19211763  
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PMID:19492417   PMID:19525225   PMID:19531027   PMID:19533041   PMID:19541408   PMID:19549714   PMID:19553005   PMID:19553815   PMID:19567200   PMID:19567590   PMID:19570915   PMID:19572978  
PMID:19574958   PMID:19588500   PMID:19609946   PMID:19615732   PMID:19615795   PMID:19621391   PMID:19636556   PMID:19660434   PMID:19711039   PMID:19723646   PMID:19726747   PMID:19734303  
PMID:19786618   PMID:19787273   PMID:19801192   PMID:19801633   PMID:19801684   PMID:19815050   PMID:19820697   PMID:19835871   PMID:19855431   PMID:19889638   PMID:19897009   PMID:19903888  
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PMID:20041213   PMID:20056178   PMID:20062086   PMID:20086095   PMID:20088406   PMID:20089415   PMID:20089844   PMID:20107185   PMID:20124452   PMID:20145951   PMID:20150971   PMID:20157617  
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Genomics

Comparative Map Data
PIK3CG
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl7106,865,278 - 106,908,980 (+)EnsemblGRCh38hg38GRCh38
GRCh387106,865,282 - 106,908,980 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh377106,505,727 - 106,549,425 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 367106,293,160 - 106,334,828 (+)NCBINCBI36hg18NCBI36
Build 347106,099,874 - 106,141,543NCBI
Celera7101,311,222 - 101,352,879 (+)NCBI
Cytogenetic Map7q22.3NCBI
HuRef7100,864,687 - 100,906,376 (+)NCBIHuRef
CHM1_17106,439,249 - 106,482,951 (+)NCBICHM1_1
CRA_TCAGchr7v27105,867,019 - 105,908,676 (+)NCBI
Pik3cg
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391232,223,128 - 32,258,675 (-)NCBIGRCm39mm39
GRCm39 Ensembl1232,223,472 - 32,258,658 (-)Ensembl
GRCm381232,173,397 - 32,208,677 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1232,173,473 - 32,208,659 (-)EnsemblGRCm38mm10GRCm38
MGSCv371232,858,262 - 32,893,514 (-)NCBIGRCm37mm9NCBIm37
MGSCv361232,760,883 - 32,793,717 (-)NCBImm8
Celera1233,627,107 - 33,665,676 (-)NCBICelera
Cytogenetic Map12A3NCBI
Pik3cg
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2648,766,778 - 48,802,098 (-)NCBI
Rnor_6.0 Ensembl651,465,908 - 51,498,337 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0651,465,696 - 51,501,234 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0661,106,730 - 61,142,184 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4650,441,892 - 50,476,931 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1650,447,918 - 50,480,237 (-)NCBI
Celera647,971,127 - 48,004,061 (-)NCBICelera
Cytogenetic Map6q16NCBI
Pik3cg
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541011,402,520 - 11,437,422 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541011,402,476 - 11,433,335 (+)NCBIChiLan1.0ChiLan1.0
PIK3CG
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.17111,569,947 - 111,611,614 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7111,570,148 - 111,611,614 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0798,841,974 - 98,885,446 (+)NCBIMhudiblu_PPA_v0panPan3
PIK3CG
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11813,576,966 - 13,611,748 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1813,570,999 - 13,611,141 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1813,224,877 - 13,259,686 (-)NCBI
ROS_Cfam_1.01813,848,210 - 13,882,893 (-)NCBI
UMICH_Zoey_3.11813,664,384 - 13,696,319 (-)NCBI
UNSW_CanFamBas_1.01813,582,574 - 13,617,381 (-)NCBI
UU_Cfam_GSD_1.01813,862,587 - 13,897,681 (-)NCBI
Pik3cg
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511855,959,678 - 55,990,585 (-)NCBI
SpeTri2.0NW_00493647917,084,006 - 17,112,264 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PIK3CG
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9106,698,207 - 106,745,099 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19106,698,200 - 106,748,217 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29117,537,774 - 117,572,944 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PIK3CG
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12175,781,812 - 75,823,404 (+)NCBI
ChlSab1.1 Ensembl2175,784,648 - 75,825,496 (+)Ensembl
Pik3cg
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473922,737,376 - 22,772,696 (-)NCBI

Position Markers
G36360  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh377106,534,067 - 106,534,247UniSTSGRCh37
Build 367106,321,303 - 106,321,483RGDNCBI36
Celera7101,339,358 - 101,339,538RGD
Cytogenetic Map7q22.3UniSTS
HuRef7100,892,854 - 100,893,034UniSTS
CRA_TCAGchr7v27105,895,155 - 105,895,335UniSTS
SHGC-35564  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh377106,545,808 - 106,546,014UniSTSGRCh37
Build 367106,333,044 - 106,333,250RGDNCBI36
Celera7101,351,095 - 101,351,301RGD
Cytogenetic Map7q22.3UniSTS
HuRef7100,904,591 - 100,904,797UniSTS
CRA_TCAGchr7v27105,906,892 - 105,907,098UniSTS
TNG Radiation Hybrid Map746358.0UniSTS
Stanford-G3 RH Map75186.0UniSTS
GeneMap99-GB4 RH Map7528.69UniSTS
Whitehead-RH Map7483.3UniSTS
NCBI RH Map71089.7UniSTS
GeneMap99-G3 RH Map75186.0UniSTS
SHGC-82136  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh377106,519,640 - 106,519,944UniSTSGRCh37
Build 367106,306,876 - 106,307,180RGDNCBI36
Celera7101,324,942 - 101,325,246RGD
Cytogenetic Map7q22.3UniSTS
HuRef7100,878,434 - 100,878,738UniSTS
CRA_TCAGchr7v27105,880,739 - 105,881,043UniSTS
TNG Radiation Hybrid Map746347.0UniSTS
STS-X83368  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh377106,546,137 - 106,546,275UniSTSGRCh37
Build 367106,333,373 - 106,333,511RGDNCBI36
Celera7101,351,424 - 101,351,562RGD
Cytogenetic Map7q22.3UniSTS
HuRef7100,904,920 - 100,905,058UniSTS
CRA_TCAGchr7v27105,907,221 - 105,907,359UniSTS
GeneMap99-GB4 RH Map7529.99UniSTS
PIK3CG_4032  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh377106,546,823 - 106,547,739UniSTSGRCh37
Build 367106,334,059 - 106,334,975RGDNCBI36
Celera7101,352,110 - 101,353,026RGD
HuRef7100,905,606 - 100,906,523UniSTS
CRA_TCAGchr7v27105,907,907 - 105,908,823UniSTS

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2122
Count of miRNA genes:704
Interacting mature miRNAs:794
Transcripts:ENST00000359195, ENST00000440650, ENST00000466738, ENST00000473541, ENST00000496166
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 19 253 5 707 1 5 9 1 8 26 8
Low 1356 1263 916 254 1220 137 1509 403 768 230 931 1289 119 1115 776 2 1
Below cutoff 956 1467 779 349 18 306 2601 1757 2790 144 430 149 48 89 2002 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NG_050579 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001282426 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001282427 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_002649 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005250443 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011516316 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011516317 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017012328 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AA810265 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC005018 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF327656 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK292684 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK313753 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY496423 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC035683 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX648341 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH236947 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471070 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HF548077 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X83368 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000359195   ⟹   ENSP00000352121
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl7106,865,479 - 106,907,145 (+)Ensembl
RefSeq Acc Id: ENST00000440650   ⟹   ENSP00000392258
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl7106,865,278 - 106,905,821 (+)Ensembl
RefSeq Acc Id: ENST00000466738
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl7106,882,164 - 106,882,936 (+)Ensembl
RefSeq Acc Id: ENST00000473541   ⟹   ENSP00000417623
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl7106,865,339 - 106,883,131 (+)Ensembl
RefSeq Acc Id: ENST00000496166   ⟹   ENSP00000419260
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl7106,865,282 - 106,908,980 (+)Ensembl
RefSeq Acc Id: NM_001282426   ⟹   NP_001269355
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh387106,865,282 - 106,908,980 (+)NCBI
HuRef7100,864,486 - 100,908,231 (+)NCBI
CHM1_17106,439,249 - 106,482,951 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001282427   ⟹   NP_001269356
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh387106,865,282 - 106,908,980 (+)NCBI
HuRef7100,864,486 - 100,908,231 (+)NCBI
CHM1_17106,439,249 - 106,482,951 (+)NCBI
Sequence:
RefSeq Acc Id: NM_002649   ⟹   NP_002640
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh387106,865,479 - 106,908,978 (+)NCBI
GRCh377106,505,723 - 106,547,592 (+)NCBI
Build 367106,293,160 - 106,334,828 (+)NCBI Archive
HuRef7100,864,486 - 100,908,231 (+)NCBI
CHM1_17106,439,450 - 106,482,951 (+)NCBI
CRA_TCAGchr7v27105,867,019 - 105,908,676 (+)ENTREZGENE
Sequence:
RefSeq Acc Id: XM_005250443   ⟹   XP_005250500
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh387106,865,448 - 106,908,978 (+)NCBI
GRCh377106,505,723 - 106,547,592 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011516316   ⟹   XP_011514618
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh387106,865,296 - 106,889,573 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011516317   ⟹   XP_011514619
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh387106,865,296 - 106,882,921 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017012328   ⟹   XP_016867817
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh387106,865,296 - 106,889,400 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_002640   ⟸   NM_002649
- UniProtKB: P48736 (UniProtKB/Swiss-Prot),   A0A024R720 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005250500   ⟸   XM_005250443
- Peptide Label: isoform X1
- UniProtKB: P48736 (UniProtKB/Swiss-Prot),   A0A024R720 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001269355   ⟸   NM_001282426
- UniProtKB: P48736 (UniProtKB/Swiss-Prot),   A0A024R720 (UniProtKB/TrEMBL),   A8K9G9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001269356   ⟸   NM_001282427
- UniProtKB: P48736 (UniProtKB/Swiss-Prot),   A0A024R720 (UniProtKB/TrEMBL),   A8K9G9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011514618   ⟸   XM_011516316
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_011514619   ⟸   XM_011516317
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_016867817   ⟸   XM_017012328
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSP00000352121   ⟸   ENST00000359195
RefSeq Acc Id: ENSP00000392258   ⟸   ENST00000440650
RefSeq Acc Id: ENSP00000419260   ⟸   ENST00000496166
RefSeq Acc Id: ENSP00000417623   ⟸   ENST00000473541
Protein Domains
C2 PI3K-type   PI3K-ABD   PI3K-RBD   PI3K/PI4K   PIK helical

Promoters
RGD ID:6806007
Promoter ID:HG_KWN:59204
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:NM_002649,   UC003VDU.1,   UC003VDV.2
Position:
Human AssemblyChrPosition (strand)Source
Build 367106,292,656 - 106,293,157 (+)MPROMDB
RGD ID:7211609
Promoter ID:EPDNEW_H11550
Type:initiation region
Name:PIK3CG_1
Description:phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunitgamma
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H11551  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh387106,865,338 - 106,865,398EPDNEW
RGD ID:7211613
Promoter ID:EPDNEW_H11551
Type:initiation region
Name:PIK3CG_2
Description:phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunitgamma
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H11550  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh387106,865,449 - 106,865,509EPDNEW

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 7q22.1-31.1(chr7:101807149-112414850)x1 copy number loss See cases [RCV000050924] Chr7:101807149..112414850 [GRCh38]
Chr7:101450429..112054905 [GRCh37]
Chr7:101237149..111842141 [NCBI36]
Chr7:7q22.1-31.1
pathogenic
GRCh38/hg38 7p22.3-q36.3(chr7:53985-159282531)x1 copy number loss See cases [RCV000052250] Chr7:53985..159282531 [GRCh38]
Chr7:53985..159075220 [GRCh37]
Chr7:149068..158767981 [NCBI36]
Chr7:7p22.3-q36.3
pathogenic
GRCh38/hg38 7q22.3-31.1(chr7:106261939-111228036)x1 copy number loss See cases [RCV000054158] Chr7:106261939..111228036 [GRCh38]
Chr7:105902385..110868092 [GRCh37]
Chr7:105689621..110655328 [NCBI36]
Chr7:7q22.3-31.1
pathogenic
NM_002649.3(PIK3CG):c.1671G>A (p.Ala557=) single nucleotide variant Malignant melanoma [RCV000067567] Chr7:106869232 [GRCh38]
Chr7:106509677 [GRCh37]
Chr7:106296913 [NCBI36]
Chr7:7q22.3
not provided
NM_002649.3(PIK3CG):c.2062-2A>C single nucleotide variant Malignant melanoma [RCV000067568] Chr7:106872711 [GRCh38]
Chr7:106513156 [GRCh37]
Chr7:106300392 [NCBI36]
Chr7:7q22.3
not provided
NM_002649.3(PIK3CG):c.2356C>T (p.Pro786Ser) single nucleotide variant Malignant melanoma [RCV000067569] Chr7:106874768 [GRCh38]
Chr7:106515213 [GRCh37]
Chr7:106302449 [NCBI36]
Chr7:7q22.3
not provided
NM_001282426.1(PIK3CG):c.3031-4677A>G single nucleotide variant Lung cancer [RCV000097384] Chr7:106900432 [GRCh38]
Chr7:106540877 [GRCh37]
Chr7:7q22.3
uncertain significance
GRCh38/hg38 7p22.3-q36.3(chr7:54185-159282390)x1 copy number loss See cases [RCV000135401] Chr7:54185..159282390 [GRCh38]
Chr7:54185..159075079 [GRCh37]
Chr7:149268..158767840 [NCBI36]
Chr7:7p22.3-q36.3
pathogenic
GRCh38/hg38 7q21.3-36.3(chr7:97419852-158923762)x3 copy number gain See cases [RCV000136717] Chr7:97419852..158923762 [GRCh38]
Chr7:97049164..158716453 [GRCh37]
Chr7:96887100..158409214 [NCBI36]
Chr7:7q21.3-36.3
pathogenic
GRCh38/hg38 7q22.1-31.31(chr7:102196924-121278641)x1 copy number loss See cases [RCV000137522] Chr7:102196924..121278641 [GRCh38]
Chr7:101912320..120918695 [GRCh37]
Chr7:101626924..120705931 [NCBI36]
Chr7:7q22.1-31.31
pathogenic
GRCh38/hg38 7q22.3-31.1(chr7:105575647-107949294)x1 copy number loss See cases [RCV000142628] Chr7:105575647..107949294 [GRCh38]
Chr7:105216094..107589739 [GRCh37]
Chr7:105003330..107376975 [NCBI36]
Chr7:7q22.3-31.1
uncertain significance
NM_001282426.2(PIK3CG):c.574G>A (p.Asp192Asn) single nucleotide variant Long QT syndrome [RCV000190177] Chr7:106868135 [GRCh38]
Chr7:106508580 [GRCh37]
Chr7:7q22.3
uncertain significance
NM_001282426.2(PIK3CG):c.1414C>T (p.Arg472Cys) single nucleotide variant Malignant tumor of prostate [RCV000206396] Chr7:106868975 [GRCh38]
Chr7:106509420 [GRCh37]
Chr7:7q22.3
uncertain significance
TMEM106B-BRAF fusion deletion Pleomorphic xanthoastrocytoma [RCV000454357] Chr7:12258147..140494267 [GRCh37]
Chr7:7p21.3-q34
pathogenic
GRCh37/hg19 7p22.3-q36.3(chr7:43360-159119707)x1 copy number loss See cases [RCV000446044] Chr7:43360..159119707 [GRCh37]
Chr7:7p22.3-q36.3
pathogenic
GRCh37/hg19 7q22.1-36.3(chr7:98969247-159119707)x3 copy number gain See cases [RCV000447709] Chr7:98969247..159119707 [GRCh37]
Chr7:7q22.1-36.3
pathogenic
GRCh37/hg19 7p22.3-q36.3(chr7:43361-159119707) copy number gain See cases [RCV000510686] Chr7:43361..159119707 [GRCh37]
Chr7:7p22.3-q36.3
pathogenic
GRCh37/hg19 7p22.3-q36.3(chr7:43361-159119707)x3 copy number gain See cases [RCV000511549] Chr7:43361..159119707 [GRCh37]
Chr7:7p22.3-q36.3
pathogenic
NM_001282426.2(PIK3CG):c.711del (p.Asp238fs) deletion Keratoconus [RCV000678669] Chr7:106868270 [GRCh38]
Chr7:106508715 [GRCh37]
Chr7:7q22.3
uncertain significance
GRCh37/hg19 7q22.1-36.3(chr7:98693388-159119707)x3 copy number gain not provided [RCV000682911] Chr7:98693388..159119707 [GRCh37]
Chr7:7q22.1-36.3
pathogenic
NC_000007.13:g.(20954043_21001537)_(114528369_114556605)inv inversion Speech-language disorder 1 [RCV000234948] Chr7:21001537..114528369 [GRCh37]
Chr7:7p15.3-q31.1
pathogenic
GRCh37/hg19 7p22.3-q36.3(chr7:44935-159126310)x3 copy number gain not provided [RCV000746280] Chr7:44935..159126310 [GRCh37]
Chr7:7p22.3-q36.3
pathogenic
GRCh37/hg19 7p22.3-q36.3(chr7:10704-159122532)x3 copy number gain not provided [RCV000746278] Chr7:10704..159122532 [GRCh37]
Chr7:7p22.3-q36.3
pathogenic
NM_001282426.2(PIK3CG):c.2455G>A (p.Asp819Asn) single nucleotide variant none provided [RCV001286079] Chr7:106879582 [GRCh38]
Chr7:106520027 [GRCh37]
Chr7:7q22.3
uncertain significance
NM_001282426.2(PIK3CG):c.711C>T (p.Pro237=) single nucleotide variant not provided [RCV000965052] Chr7:106868272 [GRCh38]
Chr7:106508717 [GRCh37]
Chr7:7q22.3
benign
NM_001282426.2(PIK3CG):c.1299C>A (p.Ile433=) single nucleotide variant not provided [RCV000916214] Chr7:106868860 [GRCh38]
Chr7:106509305 [GRCh37]
Chr7:7q22.3
likely benign
GRCh37/hg19 7p22.3-q36.3(chr7:10365-159119707)x3 copy number gain not provided [RCV000848126] Chr7:10365..159119707 [GRCh37]
Chr7:7p22.3-q36.3
pathogenic
NM_001282426.2(PIK3CG):c.18T>C (p.Tyr6=) single nucleotide variant not provided [RCV000914912] Chr7:106867579 [GRCh38]
Chr7:106508024 [GRCh37]
Chr7:7q22.3
likely benign
GRCh37/hg19 7q22.3-31.1(chr7:104506008-107408857) copy number loss See cases [RCV000993745] Chr7:104506008..107408857 [GRCh37]
Chr7:7q22.3-31.1
pathogenic
NM_001282426.2(PIK3CG):c.258C>T (p.Asp86=) single nucleotide variant not provided [RCV000918122] Chr7:106867819 [GRCh38]
Chr7:106508264 [GRCh37]
Chr7:7q22.3
benign
NM_001282426.2(PIK3CG):c.1480C>T (p.Gln494Ter) single nucleotide variant not specified [RCV001002607] Chr7:106869041 [GRCh38]
Chr7:106509486 [GRCh37]
Chr7:7q22.3
uncertain significance
NM_001282426.2(PIK3CG):c.1927A>G (p.Ile643Val) single nucleotide variant not provided [RCV000975162] Chr7:106869488 [GRCh38]
Chr7:106509933 [GRCh37]
Chr7:7q22.3
benign
NM_001282426.2(PIK3CG):c.989C>T (p.Thr330Met) single nucleotide variant not provided [RCV000888109] Chr7:106868550 [GRCh38]
Chr7:106508995 [GRCh37]
Chr7:7q22.3
benign
NM_001282426.2(PIK3CG):c.2369G>T (p.Gly790Val) single nucleotide variant not provided [RCV000886650] Chr7:106874781 [GRCh38]
Chr7:106515226 [GRCh37]
Chr7:7q22.3
likely benign
NM_001282426.2(PIK3CG):c.390G>C (p.Arg130=) single nucleotide variant not provided [RCV000908782] Chr7:106867951 [GRCh38]
Chr7:106508396 [GRCh37]
Chr7:7q22.3
benign
NM_001282426.2(PIK3CG):c.1722G>A (p.Leu574=) single nucleotide variant not provided [RCV000955377]|not specified [RCV001000632] Chr7:106869283 [GRCh38]
Chr7:106509728 [GRCh37]
Chr7:7q22.3
benign|likely benign
NM_001282426.2(PIK3CG):c.1613C>T (p.Pro538Leu) single nucleotide variant not specified [RCV001002094] Chr7:106869174 [GRCh38]
Chr7:106509619 [GRCh37]
Chr7:7q22.3
likely benign
NM_001282426.2(PIK3CG):c.1540A>G (p.Met514Val) single nucleotide variant not provided [RCV001267782] Chr7:106869101 [GRCh38]
Chr7:106509546 [GRCh37]
Chr7:7q22.3
uncertain significance
NM_001282426.2(PIK3CG):c.2760+20C>T single nucleotide variant none provided [RCV001289563] Chr7:106883183 [GRCh38]
Chr7:106523628 [GRCh37]
Chr7:7q22.3
likely benign
NM_001282426.2(PIK3CG):c.1527C>A (p.Asp509Glu) single nucleotide variant none provided [RCV001286793] Chr7:106869088 [GRCh38]
Chr7:106509533 [GRCh37]
Chr7:7q22.3
uncertain significance
NM_001282426.2(PIK3CG):c.1307G>A (p.Gly436Asp) single nucleotide variant none provided [RCV001286794] Chr7:106868868 [GRCh38]
Chr7:106509313 [GRCh37]
Chr7:7q22.3
uncertain significance

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:8978 AgrOrtholog
COSMIC PIK3CG COSMIC
Ensembl Genes ENSG00000105851 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSP00000352121 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000392258 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000417623 UniProtKB/TrEMBL
  ENSP00000419260 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000359195 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000440650 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000473541 UniProtKB/TrEMBL
  ENST00000496166 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.1070.11 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.25.40.70 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.60.40.150 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000105851 GTEx
HGNC ID HGNC:8978 ENTREZGENE
Human Proteome Map PIK3CG Human Proteome Map
InterPro ARM-type_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  C2_domain_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PI3/4_kinase_cat_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PI3/4_kinase_cat_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PI3/4_kinase_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PI3K_accessory_dom UniProtKB/TrEMBL
  PI3K_accessory_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PI3K_adapt-bd_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PI3K_C2_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PI3K_Ras-bd_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PI_Kinase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PInositide-3_kin_accessory_dom UniProtKB/Swiss-Prot
  Ubiquitin-like_domsf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:5294 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 5294 ENTREZGENE
OMIM 601232 OMIM
PANTHER PTHR10048 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam PI3_PI4_kinase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PI3K_C2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PI3K_rbd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PI3Ka UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA33311 PharmGKB
PROSITE PI3_4_KINASE_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PI3_4_KINASE_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PI3_4_KINASE_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PI3K_ABD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PI3K_C2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PI3K_RBD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PIK_HELICAL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART PI3K_C2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PI3K_rbd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PI3Ka UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PI3Kc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48371 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF54236 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF56112 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A024R720 ENTREZGENE, UniProtKB/TrEMBL
  A8K9G9 ENTREZGENE, UniProtKB/TrEMBL
  E9PDN7_HUMAN UniProtKB/TrEMBL
  L0R522_HUMAN UniProtKB/TrEMBL
  P48736 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary A4D0Q6 UniProtKB/Swiss-Prot
  Q8IV23 UniProtKB/Swiss-Prot
  Q9BZC8 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-11-24 PIK3CG  phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma    phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma  Symbol and/or name change 5135510 APPROVED
2012-07-31 PIK3CG  phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma  PIK3CG  phosphoinositide-3-kinase, catalytic, gamma polypeptide  Symbol and/or name change 5135510 APPROVED
2011-08-16 PIK3CG  phosphoinositide-3-kinase, catalytic, gamma polypeptide  PIK3CG  phosphoinositide-3-kinase, catalytic, gamma polypeptide  Symbol and/or name change 5135510 APPROVED