(-)-demecolcine decreases expression EXP 6480464 Demecolcine results in decreased expression of PFKFB4 mRNA CTD PMID:23649840 1,1-dichloroethene increases expression ISO Pfkfb4 (Mus musculus) 6480464 vinylidene chloride results in increased expression of PFKFB4 mRNA CTD PMID:26682919 1,2-dichloroethane increases expression ISO Pfkfb4 (Mus musculus) 6480464 ethylene dichloride results in increased expression of PFKFB4 mRNA CTD PMID:28960355 1,2-dimethylhydrazine multiple interactions ISO Pfkfb4 (Mus musculus) 6480464 [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of PFKFB4 mRNA CTD PMID:22206623 1,2-dimethylhydrazine decreases expression ISO Pfkfb4 (Mus musculus) 6480464 1 and 2-Dimethylhydrazine results in decreased expression of PFKFB4 mRNA CTD PMID:22206623 1-naphthyl isothiocyanate increases expression ISO Pfkfb4 (Rattus norvegicus) 6480464 1-Naphthylisothiocyanate results in increased expression of PFKFB4 mRNA CTD PMID:30723492 17beta-estradiol decreases expression EXP 6480464 Estradiol results in decreased expression of PFKFB4 mRNA CTD PMID:20106945 and PMID:21632981 17beta-estradiol multiple interactions EXP 6480464 [Estradiol co-treated with Norethindrone Acetate] results in increased expression of PFKFB4 mRNA and [Estradiol co-treated with TGFB1 protein] results in increased expression of PFKFB4 mRNA CTD PMID:22217510 and PMID:30165855 17beta-estradiol multiple interactions ISO Pfkfb4 (Rattus norvegicus) 6480464 [bisphenol A co-treated with Estradiol] results in decreased expression of PFKFB4 mRNA CTD PMID:26496021 2,3',4,4',5-Pentachlorobiphenyl decreases expression ISO Pfkfb4 (Mus musculus) 6480464 2 more ... CTD PMID:31388691 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO Pfkfb4 (Rattus norvegicus) 6480464 Tetrachlorodibenzodioxin results in decreased expression of PFKFB4 mRNA CTD PMID:21724226 and PMID:32109520 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO Pfkfb4 (Rattus norvegicus) 6480464 Tetrachlorodibenzodioxin results in increased expression of PFKFB4 mRNA CTD PMID:33387578 2,3,7,8-Tetrachlorodibenzofuran decreases expression ISO Pfkfb4 (Rattus norvegicus) 6480464 2 more ... CTD PMID:32109520 2-methylcholine affects expression EXP 6480464 beta-methylcholine affects the expression of PFKFB4 mRNA CTD PMID:21179406 4,4'-sulfonyldiphenol decreases expression EXP 6480464 bisphenol S results in decreased expression of PFKFB4 mRNA CTD PMID:27685785 4,4'-sulfonyldiphenol affects methylation ISO Pfkfb4 (Mus musculus) 6480464 bisphenol S affects the methylation of PFKFB4 gene CTD PMID:31683443 5-aza-2'-deoxycytidine affects expression EXP 6480464 Decitabine affects the expression of PFKFB4 mRNA CTD PMID:23300844 6-propyl-2-thiouracil decreases expression ISO Pfkfb4 (Rattus norvegicus) 6480464 Propylthiouracil results in decreased expression of PFKFB4 mRNA CTD PMID:24780913 ammonium chloride affects expression ISO Pfkfb4 (Rattus norvegicus) 6480464 Ammonium Chloride affects the expression of PFKFB4 mRNA CTD PMID:16483693 aristolochic acid A increases expression EXP 6480464 aristolochic acid I results in increased expression of PFKFB4 mRNA CTD PMID:33212167 arsane multiple interactions EXP 6480464 [sodium arsenate results in increased abundance of Arsenic] which results in increased expression of PFKFB4 mRNA CTD PMID:32525701 arsenic atom multiple interactions EXP 6480464 [sodium arsenate results in increased abundance of Arsenic] which results in increased expression of PFKFB4 mRNA CTD PMID:32525701 arsenous acid decreases expression EXP 6480464 Arsenic Trioxide results in decreased expression of PFKFB4 mRNA CTD PMID:27829220 aspartame multiple interactions ISO Pfkfb4 (Mus musculus) 6480464 [Fats more ... CTD PMID:23783067 benzo[a]pyrene increases expression ISO Pfkfb4 (Mus musculus) 6480464 Benzo(a)pyrene results in increased expression of PFKFB4 mRNA CTD PMID:22228805 benzo[a]pyrene increases methylation EXP 6480464 Benzo(a)pyrene results in increased methylation of PFKFB4 promoter CTD PMID:27901495 benzo[a]pyrene decreases expression EXP 6480464 Benzo(a)pyrene results in decreased expression of PFKFB4 mRNA CTD PMID:21632981 benzo[e]pyrene decreases methylation EXP 6480464 benzo(e)pyrene results in decreased methylation of PFKFB4 polyA tail CTD PMID:30157460 bisphenol A increases expression ISO Pfkfb4 (Rattus norvegicus) 6480464 bisphenol A results in increased expression of PFKFB4 mRNA CTD PMID:17010207 bisphenol A increases expression ISO Pfkfb4 (Mus musculus) 6480464 bisphenol A results in increased expression of PFKFB4 mRNA CTD PMID:34585602 bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of PFKFB4 mRNA CTD PMID:30903817 bisphenol A increases methylation ISO Pfkfb4 (Rattus norvegicus) 6480464 bisphenol A results in increased methylation of PFKFB4 gene CTD PMID:28505145 bisphenol A increases methylation ISO Pfkfb4 (Mus musculus) 6480464 bisphenol A results in increased methylation of PFKFB4 promoter CTD PMID:27312807 bisphenol A decreases expression ISO Pfkfb4 (Rattus norvegicus) 6480464 bisphenol A results in decreased expression of PFKFB4 mRNA CTD PMID:25181051 bisphenol A multiple interactions ISO Pfkfb4 (Rattus norvegicus) 6480464 [bisphenol A co-treated with Estradiol] results in decreased expression of PFKFB4 mRNA CTD PMID:26496021 butan-1-ol multiple interactions EXP 6480464 [[Gasoline co-treated with 1-Butanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in decreased expression of PFKFB4 mRNA CTD PMID:29432896 cadmium dichloride increases expression EXP 6480464 Cadmium Chloride results in increased expression of PFKFB4 mRNA CTD PMID:25596134 carbamazepine affects expression EXP 6480464 Carbamazepine affects the expression of PFKFB4 mRNA CTD PMID:25979313 chloroacetaldehyde increases expression EXP 6480464 chloroacetaldehyde results in increased expression of PFKFB4 mRNA CTD PMID:25596134 chloropicrin increases expression EXP 6480464 chloropicrin results in increased expression of PFKFB4 mRNA CTD PMID:26352163 chlorpyrifos decreases expression ISO Pfkfb4 (Mus musculus) 6480464 Chlorpyrifos results in decreased expression of PFKFB4 mRNA CTD PMID:37019170 choline multiple interactions ISO Pfkfb4 (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of PFKFB4 mRNA CTD PMID:20938992 chromium(6+) affects expression ISO Pfkfb4 (Mus musculus) 6480464 chromium hexavalent ion affects the expression of PFKFB4 mRNA CTD PMID:28472532 cidofovir anhydrous affects expression EXP 6480464 Cidofovir affects the expression of PFKFB4 mRNA CTD PMID:25596134 cisplatin increases expression EXP 6480464 Cisplatin results in increased expression of PFKFB4 mRNA and Cisplatin results in increased expression of PFKFB4 protein CTD PMID:16803524 and PMID:27594783 cisplatin decreases expression EXP 6480464 Cisplatin results in decreased expression of PFKFB4 mRNA CTD PMID:25596134 cisplatin affects expression EXP 6480464 Cisplatin affects the expression of PFKFB4 mRNA CTD PMID:23300844 clodronic acid decreases expression EXP 6480464 Clodronic Acid results in decreased expression of PFKFB4 mRNA CTD PMID:25596134 cobalt atom multiple interactions EXP 6480464 [tungsten carbide binds to Cobalt] which results in increased expression of PFKFB4 mRNA and [tungsten carbide co-treated with Cobalt] results in increased expression of PFKFB4 mRNA CTD PMID:18078969 and PMID:20105288 cobalt dichloride multiple interactions EXP 6480464 [cobaltous chloride results in decreased abundance of Iron] which results in increased expression of PFKFB4 mRNA and zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of PFKFB4 mRNA] CTD PMID:16025159 and PMID:22202117 cobalt dichloride increases expression EXP 6480464 cobaltous chloride results in increased expression of PFKFB4 mRNA CTD PMID:20105288 and PMID:22202117 curcumin decreases expression EXP 6480464 Curcumin results in decreased expression of PFKFB4 mRNA CTD PMID:17198877 cyclosporin A decreases expression EXP 6480464 Cyclosporine results in decreased expression of PFKFB4 mRNA CTD PMID:20106945 more ... cyclosporin A increases expression EXP 6480464 Cyclosporine results in increased expression of PFKFB4 mRNA CTD PMID:25596134 deguelin decreases expression EXP 6480464 deguelin results in decreased expression of PFKFB4 mRNA CTD PMID:33512557 desferrioxamine B multiple interactions EXP 6480464 [Deferoxamine results in decreased abundance of Iron] which results in increased expression of PFKFB4 mRNA CTD PMID:16025159 dexamethasone decreases expression EXP 6480464 Dexamethasone results in decreased expression of PFKFB4 mRNA CTD PMID:25047013 diarsenic trioxide decreases expression EXP 6480464 Arsenic Trioxide results in decreased expression of PFKFB4 mRNA CTD PMID:27829220 dichlorine multiple interactions ISO Pfkfb4 (Rattus norvegicus) 6480464 [Ozone co-treated with Chlorine] results in increased expression of PFKFB4 mRNA CTD PMID:18636392 dioxygen multiple interactions EXP 6480464 1-cyclopropyl-4-(4-((5-methyl-3-(3-(4-(trifluoromethoxy)phenyl)-1 more ... CTD PMID:16025159 and PMID:24403227 dioxygen increases expression EXP 6480464 Oxygen deficiency results in increased expression of PFKFB4 mRNA and Oxygen deficiency results in increased expression of PFKFB4 protein CTD PMID:16025159 more ... doxorubicin decreases expression EXP 6480464 Doxorubicin results in decreased expression of PFKFB4 mRNA CTD PMID:29803840 endosulfan increases expression ISO Pfkfb4 (Rattus norvegicus) 6480464 Endosulfan results in increased expression of PFKFB4 mRNA CTD PMID:29391264 ethanol increases expression EXP 6480464 Ethanol results in increased expression of PFKFB4 mRNA CTD PMID:23378141 ethanol multiple interactions EXP 6480464 [[Gasoline co-treated with Ethanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in decreased expression of PFKFB4 mRNA and [Ethanol co-treated with Folic Acid] results in increased expression of PFKFB4 mRNA CTD PMID:23378141 and PMID:29432896 ethyl methanesulfonate decreases expression EXP 6480464 Ethyl Methanesulfonate results in decreased expression of PFKFB4 mRNA CTD PMID:23649840 folic acid multiple interactions ISO Pfkfb4 (Mus musculus) 6480464 [1 more ... CTD PMID:20938992 and PMID:22206623 folic acid decreases expression ISO Pfkfb4 (Mus musculus) 6480464 Folic Acid results in decreased expression of PFKFB4 mRNA CTD PMID:25629700 folic acid multiple interactions EXP 6480464 [Ethanol co-treated with Folic Acid] results in increased expression of PFKFB4 mRNA CTD PMID:23378141 formaldehyde decreases expression EXP 6480464 Formaldehyde results in decreased expression of PFKFB4 mRNA CTD PMID:23649840 genistein increases expression ISO Pfkfb4 (Rattus norvegicus) 6480464 Genistein results in increased expression of PFKFB4 mRNA CTD PMID:17010207 gentamycin increases expression ISO Pfkfb4 (Rattus norvegicus) 6480464 Gentamicins results in increased expression of PFKFB4 mRNA CTD PMID:33387578 hydralazine multiple interactions EXP 6480464 [Hydralazine co-treated with Valproic Acid] results in increased expression of PFKFB4 mRNA CTD PMID:17183730 iron atom multiple interactions EXP 6480464 [cobaltous chloride results in decreased abundance of Iron] which results in increased expression of PFKFB4 mRNA and [Deferoxamine results in decreased abundance of Iron] which results in increased expression of PFKFB4 mRNA CTD PMID:16025159 iron(0) multiple interactions EXP 6480464 [cobaltous chloride results in decreased abundance of Iron] which results in increased expression of PFKFB4 mRNA and [Deferoxamine results in decreased abundance of Iron] which results in increased expression of PFKFB4 mRNA CTD PMID:16025159 isobutanol multiple interactions EXP 6480464 [[Gasoline co-treated with isobutyl alcohol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in decreased expression of PFKFB4 mRNA CTD PMID:29432896 L-methionine multiple interactions ISO Pfkfb4 (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of PFKFB4 mRNA CTD PMID:20938992 lipopolysaccharide multiple interactions EXP 6480464 [S-(1 and 2-dichlorovinyl)cysteine affects the susceptibility to Lipopolysaccharides] which results in increased expression of PFKFB4 mRNA CTD PMID:35811015 lipopolysaccharide decreases expression EXP 6480464 Lipopolysaccharides results in decreased expression of PFKFB4 mRNA CTD PMID:35811015 maneb multiple interactions ISO Pfkfb4 (Mus musculus) 6480464 [Maneb co-treated with Paraquat] results in decreased expression of PFKFB4 mRNA CTD PMID:36117858 methapyrilene decreases methylation EXP 6480464 Methapyrilene results in decreased methylation of PFKFB4 polyA tail CTD PMID:30157460 methyl methanesulfonate decreases expression EXP 6480464 Methyl Methanesulfonate results in decreased expression of PFKFB4 mRNA CTD PMID:23649840 monosodium L-glutamate multiple interactions ISO Pfkfb4 (Mus musculus) 6480464 [Fats more ... CTD PMID:23783067 motexafin gadolinium increases expression EXP 6480464 motexafin gadolinium results in increased expression of PFKFB4 mRNA CTD PMID:16357179 motexafin gadolinium multiple interactions EXP 6480464 [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of PFKFB4 mRNA CTD PMID:16357179 nickel dichloride increases expression EXP 6480464 nickel chloride results in increased expression of PFKFB4 mRNA CTD PMID:21455298 Nonylphenol increases expression ISO Pfkfb4 (Rattus norvegicus) 6480464 nonylphenol results in increased expression of PFKFB4 mRNA CTD PMID:17010207 oxaliplatin decreases expression EXP 6480464 oxaliplatin results in decreased expression of PFKFB4 mRNA CTD PMID:17762391 ozone multiple interactions ISO Pfkfb4 (Rattus norvegicus) 6480464 [Ozone co-treated with Chlorine] results in increased expression of PFKFB4 mRNA CTD PMID:18636392 ozone multiple interactions EXP 6480464 [Air Pollutants results in increased abundance of Ozone] which affects the expression of PFKFB4 mRNA CTD PMID:35430440 ozone multiple interactions ISO Pfkfb4 (Mus musculus) 6480464 [Air Pollutants results in increased abundance of Ozone] which results in decreased expression of PFKFB4 mRNA CTD PMID:34911549 paracetamol affects expression ISO Pfkfb4 (Mus musculus) 6480464 Acetaminophen affects the expression of PFKFB4 mRNA CTD PMID:17562736 paraquat affects expression ISO Pfkfb4 (Rattus norvegicus) 6480464 Paraquat affects the expression of PFKFB4 mRNA CTD PMID:15206577 paraquat multiple interactions ISO Pfkfb4 (Mus musculus) 6480464 [Maneb co-treated with Paraquat] results in decreased expression of PFKFB4 mRNA CTD PMID:36117858 quercetin decreases expression EXP 6480464 Quercetin results in decreased expression of PFKFB4 mRNA CTD PMID:21632981 rotenone decreases expression EXP 6480464 Rotenone results in decreased expression of PFKFB4 mRNA CTD PMID:33512557 S-(1,2-dichlorovinyl)-L-cysteine multiple interactions EXP 6480464 [S-(1 and 2-dichlorovinyl)cysteine affects the susceptibility to Lipopolysaccharides] which results in increased expression of PFKFB4 mRNA CTD PMID:35811015 sodium arsenate multiple interactions EXP 6480464 [sodium arsenate results in increased abundance of Arsenic] which results in increased expression of PFKFB4 mRNA CTD PMID:32525701 sotorasib multiple interactions EXP 6480464 [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of PFKFB4 mRNA CTD PMID:36139627 sunitinib increases expression EXP 6480464 Sunitinib results in increased expression of PFKFB4 mRNA CTD PMID:31533062 testosterone decreases expression ISO Pfkfb4 (Mus musculus) 6480464 Testosterone deficiency results in decreased expression of PFKFB4 mRNA CTD PMID:33848595 testosterone multiple interactions ISO Pfkfb4 (Mus musculus) 6480464 1 more ... CTD PMID:33848595 thapsigargin decreases expression EXP 6480464 Thapsigargin results in decreased expression of PFKFB4 mRNA CTD PMID:22378314 thimerosal decreases expression EXP 6480464 Thimerosal results in decreased expression of PFKFB4 mRNA CTD PMID:27188386 trametinib multiple interactions EXP 6480464 [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of PFKFB4 mRNA CTD PMID:36139627 tributylstannane increases expression ISO Pfkfb4 (Mus musculus) 6480464 tributyltin results in increased expression of PFKFB4 mRNA CTD PMID:31939706 trichloroethene affects expression ISO Pfkfb4 (Rattus norvegicus) 6480464 Trichloroethylene affects the expression of PFKFB4 mRNA CTD PMID:33387578 trichostatin A affects expression EXP 6480464 trichostatin A affects the expression of PFKFB4 mRNA CTD PMID:28542535 triclosan decreases expression EXP 6480464 Triclosan results in decreased expression of PFKFB4 mRNA CTD PMID:30510588 triptonide decreases expression ISO Pfkfb4 (Mus musculus) 6480464 triptonide results in decreased expression of PFKFB4 mRNA CTD PMID:33045310 Tungsten carbide multiple interactions EXP 6480464 [tungsten carbide binds to Cobalt] which results in increased expression of PFKFB4 mRNA and [tungsten carbide co-treated with Cobalt] results in increased expression of PFKFB4 mRNA CTD PMID:18078969 and PMID:20105288 tunicamycin decreases expression EXP 6480464 Tunicamycin results in decreased expression of PFKFB4 mRNA CTD PMID:22378314 uranium atom affects expression EXP 6480464 Uranium affects the expression of PFKFB4 mRNA CTD PMID:15672453 urethane increases expression EXP 6480464 Urethane results in increased expression of PFKFB4 mRNA CTD PMID:28818685 valproic acid affects expression ISO Pfkfb4 (Mus musculus) 6480464 Valproic Acid affects the expression of PFKFB4 mRNA CTD PMID:17292431 valproic acid multiple interactions EXP 6480464 [Hydralazine co-treated with Valproic Acid] results in increased expression of PFKFB4 mRNA CTD PMID:17183730 vincristine decreases expression EXP 6480464 Vincristine results in decreased expression of PFKFB4 mRNA CTD PMID:23649840 vorinostat decreases expression EXP 6480464 vorinostat results in decreased expression of PFKFB4 mRNA CTD PMID:27188386 zinc acetate multiple interactions EXP 6480464 [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of PFKFB4 mRNA CTD PMID:16357179 zinc acetate increases expression EXP 6480464 Zinc Acetate results in increased expression of PFKFB4 mRNA CTD PMID:16357179 zinc dichloride multiple interactions EXP 6480464 zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of PFKFB4 mRNA] CTD PMID:22202117 zoledronic acid increases expression EXP 6480464 zoledronic acid results in increased expression of PFKFB4 mRNA CTD PMID:24714768 and PMID:25596134