SCN8A (sodium voltage-gated channel alpha subunit 8)

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Gene: SCN8A (sodium voltage-gated channel alpha subunit 8) Homo sapiens

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Symbol:

SCN8A

Name:

sodium voltage-gated channel alpha subunit 8

RGD ID:

1351349

HGNC Page

HGNC

Description:

Enables voltage-gated sodium channel activity. Predicted to be involved in several processes, including nervous system development; neuronal action potential; and sodium ion transmembrane transport. Predicted to act upstream of or within several processes, including adult walking behavior; muscle organ development; and sensory perception of sound. Located in cell junction and plasma membrane. Implicated in benign familial neonatal epilepsy and developmental and epileptic encephalopathy 13.

Type:

protein-coding

RefSeq Status:

REVIEWED

Previously known as:

BFIS5; CerIII; CIAT; DEE13; EIEE13; FLJ33996; hNa6/Scn8a voltage-gated sodium channel; MED; MYOCL2; NaCh6; Nav1.6; PN4; sodium channel protein type 8 subunit alpha; sodium channel protein type VIII subunit alpha; sodium channel, voltage gated, type VIII alpha subunit; sodium channel, voltage gated, type VIII, alpha subunit; voltage-gated sodium channel subunit alpha Nav1.6

RGD Orthologs

Mouse

Rat

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

Allele / Splice:

See ClinVar data

Latest Assembly:

GRCh38 - Human Genome Assembly GRCh38

Position:

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	12	51,591,233 - 51,812,864 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p13 Ensembl	12	51,590,266 - 51,812,864 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	12	51,985,017 - 52,206,648 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	12	50,271,287 - 50,488,574 (+)	NCBI	NCBI36		hg18	NCBI36
Build 34	12	50,271,286 - 50,488,365	NCBI
Celera	12	50,787,152 - 51,004,408 (+)	NCBI
Cytogenetic Map	12	q13.13	NCBI
HuRef	12	49,089,349 - 49,239,456 (+)	NCBI		HuRef
CHM1_1	12	51,951,468 - 52,173,106 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	12	51,554,795 - 51,776,384 (+)	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar