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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 17beta-estradiol | multiple interactions | EXP | | 6480464 | [Estradiol co-treated with TGFB1 protein] results in decreased expression of MESP1 mRNA | CTD | PMID:30165855 | 2,2',4,4',5,5'-hexachlorobiphenyl | decreases expression | EXP | | 6480464 | 2 more ... | CTD | PMID:23146750 | 2,2',4,4'-Tetrabromodiphenyl ether | decreases expression | EXP | | 6480464 | 2 more ... | CTD | PMID:23146750 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | RGD:1323369 | 6480464 | Tetrachlorodibenzodioxin affects the expression of MESP1 mRNA | CTD | PMID:24058054, PMID:26377647 | 3-methylcholanthrene | multiple interactions | EXP | | 6480464 | Methylcholanthrene promotes the reaction [AHR protein binds to MESP1 promoter] | CTD | PMID:20348232 | 4,4'-sulfonyldiphenol | increases expression | ISO | RGD:1323369 | 6480464 | bis(4-hydroxyphenyl)sulfone results in increased expression of MESP1 mRNA | CTD | PMID:30951980 | 5-fluorouracil | decreases expression | ISO | RGD:1323369 | 6480464 | Fluorouracil results in decreased expression of MESP1 mRNA | CTD | PMID:26272751 | 6-propyl-2-thiouracil | decreases expression | ISO | RGD:1311751 | 6480464 | Propylthiouracil results in decreased expression of MESP1 mRNA | CTD | PMID:24780913 | all-trans-retinoic acid | decreases expression | EXP | | 6480464 | Tretinoin results in decreased expression of MESP1 mRNA | CTD | PMID:23724009 | all-trans-retinoic acid | decreases expression | ISO | RGD:1323369 | 6480464 | Tretinoin results in decreased expression of MESP1 mRNA | CTD | PMID:26272751 | aristolochic acid | increases expression | EXP | | 6480464 | aristolochic acid I results in increased expression of MESP1 mRNA | CTD | PMID:33212167 | benzo[a]pyrene | decreases expression | EXP | | 6480464 | Benzo(a)pyrene results in decreased expression of MESP1 mRNA | CTD | PMID:22316170 | benzo[a]pyrene | affects methylation | EXP | | 6480464 | Benzo(a)pyrene affects the methylation of MESP1 promoter | CTD | PMID:27901495 | benzo[a]pyrene | decreases methylation | EXP | | 6480464 | Benzo(a)pyrene results in decreased methylation of MESP1 3' UTR | CTD | PMID:27901495 | benzylpenicillin | decreases expression | ISO | RGD:1323369 | 6480464 | Penicillin G results in decreased expression of MESP1 mRNA | CTD | PMID:26272751 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of MESP1 mRNA | CTD | PMID:23146750 | bisphenol A | decreases expression | ISO | RGD:1311751 | 6480464 | bisphenol A results in decreased expression of MESP1 mRNA | CTD | PMID:25181051 | bisphenol F | increases expression | ISO | RGD:1323369 | 6480464 | bisphenol F results in increased expression of MESP1 mRNA | CTD | PMID:30951980 | butanal | increases expression | EXP | | 6480464 | butyraldehyde results in increased expression of MESP1 mRNA | CTD | PMID:26079696 | cadmium atom | increases expression | EXP | | 6480464 | Cadmium results in increased expression of MESP1 mRNA | CTD | PMID:24376830 | carbamazepine | affects expression | EXP | | 6480464 | Carbamazepine affects the expression of MESP1 mRNA | CTD | PMID:25979313 | carbon nanotube | decreases expression | ISO | RGD:1323369 | 6480464 | Nanotubes, Carbon analog results in decreased expression of MESP1 mRNA | CTD | PMID:25554681 | cefaloridine | decreases expression | ISO | RGD:1311751 | 6480464 | Cephaloridine results in decreased expression of MESP1 mRNA | CTD | PMID:18500788 | chlorpyrifos | decreases expression | ISO | RGD:1323369 | 6480464 | Chlorpyrifos results in decreased expression of MESP1 mRNA | CTD | PMID:32715474 | choline | multiple interactions | ISO | RGD:1323369 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of and results in increased expression of MESP1 more ... | CTD | PMID:20938992 | cisplatin | multiple interactions | EXP | | 6480464 | [Cisplatin co-treated with jinfukang] results in increased expression of MESP1 mRNA | CTD | PMID:27392435 | dexamethasone | decreases expression | EXP | | 6480464 | Dexamethasone results in decreased expression of MESP1 mRNA | CTD | PMID:34742744 | dextran sulfate | increases expression | ISO | RGD:1323369 | 6480464 | Dextran Sulfate results in increased expression of MESP1 mRNA | CTD | PMID:35093514 | dorsomorphin | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of MESP1 mRNA | CTD | PMID:27188386 | folic acid | multiple interactions | ISO | RGD:1323369 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of and results in increased expression of MESP1 more ... | CTD | PMID:20938992 | L-methionine | multiple interactions | ISO | RGD:1323369 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of and results in increased expression of MESP1 more ... | CTD | PMID:20938992 | lead(0) | affects expression | EXP | | 6480464 | Lead affects the expression of MESP1 mRNA | CTD | PMID:28903495 | lead(2+) | affects expression | EXP | | 6480464 | Lead affects the expression of MESP1 mRNA | CTD | PMID:28903495 | leflunomide | decreases expression | EXP | | 6480464 | leflunomide results in decreased expression of MESP1 mRNA | CTD | PMID:28988120 | lithium chloride | increases expression | ISO | RGD:1323369 | 6480464 | Lithium Chloride results in increased expression of MESP1 mRNA | CTD | PMID:26272751 | Monobutylphthalate | affects expression | ISO | RGD:1323369 | 6480464 | monobutyl phthalate affects the expression of MESP1 mRNA | CTD | PMID:19162170 | ozone | multiple interactions | ISO | RGD:1323369 | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of MESP1 mRNA, [Air Pollutants results in increased abundance of Ozone] which results in decreased expression of MESP1 mRNA | CTD | PMID:34911549 | perfluorooctanoic acid | decreases expression | EXP | | 6480464 | perfluorooctanoic acid results in decreased expression of MESP1 mRNA | CTD | PMID:23146750 | phenylmercury acetate | decreases expression | EXP | | 6480464 | Phenylmercuric Acetate results in decreased expression of MESP1 mRNA | CTD | PMID:26272509 | phenylmercury acetate | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of MESP1 mRNA | CTD | PMID:27188386 | phenytoin | increases expression | ISO | RGD:1323369 | 6480464 | Phenytoin results in increased expression of MESP1 mRNA | CTD | PMID:26272751 | resveratrol | multiple interactions | EXP | | 6480464 | [Plant Extracts co-treated with Resveratrol] results in decreased expression of MESP1 mRNA | CTD | PMID:23557933 | rotenone | increases expression | EXP | | 6480464 | Rotenone results in increased expression of MESP1 mRNA | CTD | PMID:29955902 | saccharin | decreases expression | ISO | RGD:1323369 | 6480464 | Saccharin results in decreased expression of MESP1 mRNA | CTD | PMID:26272751 | SB 431542 | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of MESP1 mRNA | CTD | PMID:27188386 | sodium arsenite | increases expression | EXP | | 6480464 | sodium arsenite results in increased expression of MESP1 mRNA | CTD | PMID:34032870 | temozolomide | decreases expression | EXP | | 6480464 | Temozolomide results in decreased expression of MESP1 mRNA | CTD | PMID:31758290 | tetrachloroethene | decreases expression | ISO | RGD:1323369 | 6480464 | Tetrachloroethylene results in decreased expression of MESP1 mRNA | CTD | PMID:28973375 | tetraphene | increases expression | ISO | RGD:1323369 | 6480464 | benz(a)anthracene results in increased expression of MESP1 mRNA | CTD | PMID:26377693 | thapsigargin | increases expression | EXP | | 6480464 | Thapsigargin results in increased expression of MESP1 mRNA | CTD | PMID:29453283 | tributylstannane | decreases expression | ISO | RGD:1311751 | 6480464 | tributyltin results in decreased expression of MESP1 mRNA | CTD | PMID:31129395 | trichloroethene | increases expression | ISO | RGD:1311751 | 6480464 | Trichloroethylene results in increased expression of MESP1 mRNA | CTD | PMID:33387578 | valproic acid | increases methylation | EXP | | 6480464 | Valproic Acid results in increased methylation of MESP1 gene | CTD | PMID:29154799 | valproic acid | increases expression | ISO | RGD:1323369 | 6480464 | Valproic Acid results in increased expression of MESP1 mRNA | CTD | PMID:26272751 | vorinostat | decreases expression | EXP | | 6480464 | vorinostat results in decreased expression of MESP1 mRNA | CTD | PMID:27188386 | |