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Gene: SHBG (sex hormone binding globulin) Homo sapiens
Symbol: SHBG
Name: sex hormone binding globulin
Description: Predicted to have steroid binding activity. Localizes to the extracellular exosome. Implicated in endometrial cancer and type 2 diabetes mellitus. Biomarker of diabetes mellitus.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ABP; androgen binding protein; MGC126834; MGC138391; SBP; sex hormone-binding globulin; sex steroid-binding protein; TEBG; testis-specific androgen-binding protein; testosterone-binding beta-globulin; testosterone-estradiol-binding globulin; testosterone-estrogen-binding globulin
Mus musculus (house mouse) : Shbg (sex hormone binding globulin)  MGI  Alliance
Rattus norvegicus (Norway rat) : Shbg (sex hormone binding globulin)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Shbg (sex hormone binding globulin)
Pan paniscus (bonobo/pygmy chimpanzee) : SHBG (sex hormone binding globulin)
Canis lupus familiaris (dog) : SHBG (sex hormone binding globulin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Shbg (sex hormone binding globulin)
Sus scrofa (pig) : SHBG (sex hormone binding globulin)
Chlorocebus sabaeus (African green monkey) : SHBG (sex hormone binding globulin)
Heterocephalus glaber (naked mole-rat) : Shbg (sex hormone binding globulin)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl177,613,946 - 7,633,382 (+)Ensembl
GRCh38177,614,064 - 7,633,383 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37177,517,382 - 7,536,700 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36177,474,216 - 7,477,395 (+)NCBINCBI36hg18NCBI36
Build 34177,474,215 - 7,477,395NCBI
Celera177,543,810 - 7,563,117 (+)NCBI
Cytogenetic Map17p13.1NCBI
HuRef177,411,426 - 7,430,707 (+)NCBIHuRef
CHM1_1177,526,291 - 7,545,882 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on SHBG
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 736172
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2020-02-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.