SHBG (sex hormone binding globulin) - Rat Genome Database

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Gene: SHBG (sex hormone binding globulin) Homo sapiens
Analyze
Symbol: SHBG
Name: sex hormone binding globulin
RGD ID: 736172
HGNC Page HGNC:10839
Description: Predicted to enable steroid binding activity. Located in extracellular exosome. Implicated in endometrial cancer and type 2 diabetes mellitus. Biomarker of diabetes mellitus.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: ABP; androgen binding protein; MGC126834; MGC138391; SBP; sex hormone-binding globulin; sex steroid-binding protein; TEBG; testis-specific androgen-binding protein; testosterone-binding beta-globulin; testosterone-estradiol-binding globulin; testosterone-estrogen-binding globulin
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38177,614,064 - 7,633,372 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl177,613,946 - 7,633,382 (+)EnsemblGRCh38hg38GRCh38
GRCh37177,517,382 - 7,536,690 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36177,474,216 - 7,477,395 (+)NCBINCBI36Build 36hg18NCBI36
Build 34177,474,215 - 7,477,395NCBI
Celera177,543,810 - 7,563,117 (+)NCBICelera
Cytogenetic Map17p13.1NCBI
HuRef177,411,426 - 7,430,707 (+)NCBIHuRef
CHM1_1177,526,291 - 7,545,881 (+)NCBICHM1_1
T2T-CHM13v2.0177,518,285 - 7,537,563 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
SHBGHumandiabetes mellitus  IEP 2313784protein:increased expression:plasmaRGD 
SHBGHumanendometrial cancer  IAGP 1625245DNA:polymorphism:exon:p.D327N (human)RGD 
SHBGHumanMetabolic Syndrome  IEP 2313785protein:decreased expression:serumRGD 
SHBGHumantype 2 diabetes mellitus susceptibilityIAGP 2313782DNA, protein:SNPs, decreased expression:rs6257, rs6259, plasma (human)RGD 
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
SHBGHumancommon variable immunodeficiency  IAGPRGD:156438206|RGD:268906958554872ClinVar Annotator: match by term: Common variable immunodeficiencyClinVarPMID:28492532
SHBGHumancongenital myasthenic syndrome 2A  IAGPRGD:1564392598554872ClinVar Annotator: match by term: Congenital myasthenic syndrome 2AClinVarPMID:28492532
SHBGHumandyskeratosis congenita  IAGPRGD:268906958554872ClinVar Annotator: match by term: Dyskeratosis congenitaClinVarPMID:28492532
SHBGHumanLi-Fraumeni syndrome  IAGPRGD:1564413688554872ClinVar Annotator: match by term: Li-Fraumeni syndromeClinVarPMID:20522432|PMID:21056402|PMID:23172776|PMID:26681312|PMID:28492532
SHBGHumanvery long chain acyl-CoA dehydrogenase deficiency  IAGPRGD:1564392598554872ClinVar Annotator: match by term: Very long chain acyl-CoA dehydrogenase deficiencyClinVarPMID:28492532
SHBGHumanvery long chain acyl-CoA dehydrogenase deficiency  IAGPRGD:1564475498554872ClinVar Annotator: match by term: Very long chain acyl-CoA dehydrogenase deficiencyClinVarPMID:11590124|PMID:28492532|PMID:9973285
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
SHBGHumanalcohol use disorder  EXP 11554173CTD Direct Evidence: marker/mechanismCTDPMID:8590623
SHBGHumandilated cardiomyopathy  EXP 11554173CTD Direct Evidence: marker/mechanismCTDPMID:25996886
SHBGHumanimpotence  EXP 11554173CTD Direct Evidence: marker/mechanismCTDPMID:17961146
SHBGHumanmalignant mesothelioma  EXP 11554173CTD Direct Evidence: marker/mechanismCTDPMID:28377727
SHBGHumanMetabolic Syndrome  EXP 11554173CTD Direct Evidence: marker/mechanismCTDPMID:16968811|PMID:17992261
SHBGHumanProstatic Neoplasms  EXP 11554173CTD Direct Evidence: marker/mechanismCTDPMID:17220347
SHBGHumantype 2 diabetes mellitus  EXP 11554173CTD Direct Evidence: marker/mechanismCTDPMID:21982312

1 to 20 of 211 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
SHBGHuman(S)-naringenin affects bindingEXP 6480464naringenin binds to SHBG proteinCTDPMID:25349334
SHBGHuman1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane multiple interactionsEXP 6480464o,p'-DDT inhibits the reaction [Dihydrotestosterone binds to SHBG protein]CTDPMID:9171990
SHBGHuman1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane affects bindingEXP 6480464o,p'-DDT binds to SHBG proteinCTDPMID:25349334
SHBGHuman1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane multiple interactionsISORGD:36716480464o,p'-DDT inhibits the reaction [Dihydrotestosterone binds to SHBG protein]CTDPMID:9171990
SHBGHuman17alpha-ethynylestradiol multiple interactionsEXP 6480464[Ethinyl Estradiol co-treated with drospirenone] results in increased expression of SHBG protein; [Ethinyl Estradiol co-treated more ...CTDPMID:10899481|PMID:11245553|PMID:12586319|PMID:14981370|PMID:16982228|PMID:17519148
SHBGHuman17alpha-ethynylestradiol affects bindingEXP 6480464Ethinyl Estradiol binds to SHBG proteinCTDPMID:25349334
SHBGHuman17alpha-ethynylestradiol increases expressionEXP 6480464Ethinyl Estradiol results in increased expression of SHBG proteinCTDPMID:11907703|PMID:17374706
SHBGHuman17beta-estradiol multiple interactionsEXP 6480464Copper promotes the reaction [Estradiol results in increased expression of SHBG mRNA]; ESR1 protein promotes more ...CTDPMID:16551731|PMID:19685012
SHBGHuman17beta-estradiol decreases expressionISORGD:112896480464Estradiol results in decreased expression of SHBG mRNACTDPMID:39298647
SHBGHuman17beta-estradiol affects bindingEXP 6480464Estradiol binds to SHBG proteinCTDPMID:25349334
SHBGHuman17beta-estradiol increases expressionEXP 6480464Estradiol results in increased expression of SHBG mRNA; Estradiol results in increased expression of SHBG more ...CTDPMID:16551731|PMID:17484513|PMID:19685012|PMID:21632903
SHBGHuman17beta-hydroxy-5alpha-androstan-3-one multiple interactionsEXP 6480464delta-hexachlorocyclohexane inhibits the reaction [Dihydrotestosterone binds to SHBG protein]; Hexachlorocyclohexane inhibits the reaction [Dihydrotestosterone binds more ...CTDPMID:9171990
SHBGHuman17beta-hydroxy-5alpha-androstan-3-one affects bindingEXP 6480464Dihydrotestosterone binds to SHBG proteinCTDPMID:25349334
SHBGHuman17beta-hydroxy-5alpha-androstan-3-one multiple interactionsISORGD:36716480464Atrazine inhibits the reaction [Dihydrotestosterone binds to SHBG protein]; DDT analog inhibits the reaction [Dihydrotestosterone more ...CTDPMID:9171990
SHBGHuman2,2',4,4'-Tetrabromodiphenyl ether decreases expressionEXP 64804642,2',4,4'-tetrabromodiphenyl ether results in decreased expression of SHBG proteinCTDPMID:31675489
SHBGHuman2,2'-Dihydroxy-4-methoxybenzophenone affects bindingEXP 6480464dioxybenzone binds to SHBG proteinCTDPMID:25349334
SHBGHuman2,3,4,5-Tetrachloro-4'-biphenylol affects bindingEXP 64804644-hydroxy-2',3',4'-5'-tetrachlorobiphenyl binds to SHBG proteinCTDPMID:25349334
SHBGHuman2,3,7,8-tetrachlorodibenzodioxine increases expressionISORGD:36716480464Tetrachlorodibenzodioxin results in increased expression of SHBG mRNACTDPMID:33387578
SHBGHuman2,4,6-tribromophenol increases expressionEXP 64804642,4,6-tribromophenol results in increased expression of SHBG mRNACTDPMID:31675489
SHBGHuman2,4,6-trinitrobenzenesulfonic acid increases expressionISORGD:112896480464Trinitrobenzenesulfonic Acid results in increased expression of SHBG mRNACTDPMID:17982090

1 to 20 of 211 rows

Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
SHBGHumanprimary spermatocyte growth  ISORGD:36719068941 RGDPMID:15215204|REF_RGD_ID:1625248

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
SHBGHumanextracellular exosome located_inHDA 150520179 PMID:23533145UniProtPMID:23533145
SHBGHumanextracellular region located_inIEAUniProtKB-SubCell:SL-0243150520179 UniProtGO_REF:0000044
SHBGHumanextracellular region located_inNAS 150520179 PMID:14718574UniProtPMID:14718574
SHBGHumanextracellular region located_inIEAUniProtKB-KW:KW-0964150520179 UniProtGO_REF:0000043

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
SHBGHumanandrogen binding enablesTAS 150520179 PMID:2587256PINCPMID:2587256
SHBGHumanlipid binding enablesIEAUniProtKB-KW:KW-0446150520179 UniProtGO_REF:0000043
SHBGHumanprotein binding  ISORGD:21849068941 RGDPMID:15927785|REF_RGD_ID:1625246
SHBGHumanprotein binding enablesIPIUniProtKB:P98158150520179 PMID:16143106UniProtPMID:16143106
SHBGHumanprotein binding  ISORGD:32389068941 RGDPMID:15927785|REF_RGD_ID:1625246
SHBGHumansteroid binding enablesIEAUniProtKB-KW:KW-0754150520179 UniProtGO_REF:0000043
SHBGHumansteroid binding enablesIBAPANTHER:PTN002778768|ZFIN:ZDB-GENE-030131-1324150520179 GO_CentralGO_REF:0000033


#
Reference Title
Reference Citation
1. Lower sex hormone-binding globulin is more strongly associated with metabolic syndrome than lower total testosterone in older men: the Health in Men Study. Chubb SA, etal., Eur J Endocrinol. 2008 Jun;158(6):785-92.
2. Sex hormone-binding globulin and testosterone in individuals with childhood diabetes. Danielson KK, etal., Diabetes Care. 2008 Jun;31(6):1207-13. Epub 2008 Mar 17.
3. Sex hormone-binding globulin and risk of type 2 diabetes in women and men. Ding EL, etal., N Engl J Med. 2009 Sep 17;361(12):1152-63. Epub 2009 Aug 5.
4. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
5. Association of endometrial cancer risk with a functional polymorphism (Asp(327)Asn) in the sex hormone-binding globulin gene. Kataoka N, etal., Cancer. 2007 Apr 1;109(7):1296-302.
6. Suppression of SOCS3 expression in the pancreatic beta-cell leads to resistance to type 1 diabetes. Mori H, etal., Biochem Biophys Res Commun. 2007 Aug 10;359(4):952-8. Epub 2007 Jun 4.
7. Serum sex hormone-binding globulin, a determinant of cardiometabolic disorders independent of abdominal obesity and insulin resistance in elderly men and women. Onat A, etal., Metabolism. 2007 Oct;56(10):1356-62.
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
1 to 10 of 30 rows
PMID:1400872   PMID:2249477   PMID:2587256   PMID:2608061   PMID:2956125   PMID:2956126   PMID:3542030   PMID:3569533   PMID:3702459   PMID:7714097   PMID:8964583   PMID:10391209  
PMID:10419028   PMID:10675319   PMID:11140838   PMID:11473114   PMID:12015315   PMID:12039072   PMID:12054810   PMID:12065592   PMID:12081841   PMID:12151349   PMID:12228253   PMID:12235141  
PMID:12477932   PMID:12603009   PMID:12679434   PMID:12753385   PMID:12800098   PMID:12861158   PMID:14568572   PMID:14671199   PMID:14694008   PMID:14718574   PMID:14764814   PMID:15028279  
PMID:15111517   PMID:15146368   PMID:15193539   PMID:15199113   PMID:15292305   PMID:15489334   PMID:15574421   PMID:15634719   PMID:15664449   PMID:15668497   PMID:15755867   PMID:15784702  
PMID:15862967   PMID:15879463   PMID:15894658   PMID:16143106   PMID:16155373   PMID:16251630   PMID:16331562   PMID:16335952   PMID:16394089   PMID:16757555   PMID:16896040   PMID:16926255  
PMID:16949385   PMID:16982738   PMID:17027360   PMID:17027364   PMID:17077994   PMID:17176215   PMID:17189294   PMID:17220347   PMID:17258903   PMID:17411440   PMID:17507624   PMID:17684316  
PMID:17706202   PMID:17890489   PMID:17893265   PMID:17952758   PMID:17992261   PMID:18047273   PMID:18056923   PMID:18188141   PMID:18192296   PMID:18312604   PMID:18318428   PMID:18437557  
PMID:18464913   PMID:18477206   PMID:18505907   PMID:18624398   PMID:18636124   PMID:18676680   PMID:18681858   PMID:18767927   PMID:18937076   PMID:18949680   PMID:18980759   PMID:19005973  
PMID:19015200   PMID:19022535   PMID:19064566   PMID:19064572   PMID:19086053   PMID:19091090   PMID:19124506   PMID:19168589   PMID:19170196   PMID:19179433   PMID:19194113   PMID:19196890  
PMID:19327605   PMID:19336534   PMID:19416531   PMID:19429700   PMID:19453261   PMID:19534810   PMID:19557594   PMID:19574343   PMID:19598235   PMID:19625176   PMID:19649728   PMID:19672706  
1 to 10 of 30 rows



SHBG
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38177,614,064 - 7,633,372 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl177,613,946 - 7,633,382 (+)EnsemblGRCh38hg38GRCh38
GRCh37177,517,382 - 7,536,690 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36177,474,216 - 7,477,395 (+)NCBINCBI36Build 36hg18NCBI36
Build 34177,474,215 - 7,477,395NCBI
Celera177,543,810 - 7,563,117 (+)NCBICelera
Cytogenetic Map17p13.1NCBI
HuRef177,411,426 - 7,430,707 (+)NCBIHuRef
CHM1_1177,526,291 - 7,545,881 (+)NCBICHM1_1
T2T-CHM13v2.0177,518,285 - 7,537,563 (+)NCBIT2T-CHM13v2.0
Shbg
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391169,501,108 - 69,508,852 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1169,505,630 - 69,508,731 (-)EnsemblGRCm39 Ensembl
GRCm381169,610,282 - 69,618,026 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1169,614,804 - 69,617,905 (-)EnsemblGRCm38mm10GRCm38
MGSCv371169,428,318 - 69,431,407 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361170,198,988 - 70,201,975 (-)NCBIMGSCv36mm8
MGSCv361169,431,011 - 69,434,063 (-)NCBIMGSCv36mm8
Cytogenetic Map11B3NCBI
cM Map1142.86NCBI
Shbg
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81054,831,716 - 54,849,162 (-)NCBIGRCr8
mRatBN7.21054,332,939 - 54,350,409 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1054,332,941 - 54,351,057 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1058,995,368 - 58,998,537 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01058,483,914 - 58,487,083 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01053,991,608 - 53,994,780 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01056,219,861 - 56,237,354 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1056,219,858 - 56,223,245 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01055,965,499 - 55,983,036 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41056,432,474 - 56,435,654 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11056,446,096 - 56,449,277 (-)NCBI
Celera1053,487,385 - 53,490,565 (-)NCBICelera
Cytogenetic Map10q24NCBI
Shbg
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554679,301,173 - 9,305,010 (-)NCBIChiLan1.0ChiLan1.0
SHBG
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21915,221,821 - 15,235,544 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11717,187,912 - 17,193,499 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0177,658,831 - 7,664,631 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1177,645,188 - 7,650,552 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl177,645,187 - 7,650,552 (+)Ensemblpanpan1.1panPan2
SHBG
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1532,535,738 - 32,540,627 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl532,537,138 - 32,540,624 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha532,674,555 - 32,679,801 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0532,640,395 - 32,645,639 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl532,642,122 - 32,645,637 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1532,608,086 - 32,613,336 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0532,564,351 - 32,569,590 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0532,743,466 - 32,748,710 (+)NCBIUU_Cfam_GSD_1.0
Shbg
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560247,419,255 - 47,423,061 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936595894,040 - 897,733 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936595894,048 - 897,249 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SHBG
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11252,914,711 - 52,919,092 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21255,255,233 - 55,259,078 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SHBG
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1167,002,380 - 7,012,170 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl167,008,682 - 7,012,764 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605914,395,808 - 14,399,825 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Shbg
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462478610,234,484 - 10,239,034 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in SHBG
72 total Variants

1 to 10 of 93 rows
Name
Type
Condition(s)
Position(s)
Clinical significance
GRCh38/hg38 17p13.2-13.1(chr17:5732977-8038822)x1 copy number loss See cases [RCV000051043] Chr17:5732977..8038822 [GRCh38]
Chr17:5636297..7942140 [GRCh37]
Chr17:5577021..7882865 [NCBI36]
Chr17:17p13.2-13.1
pathogenic
GRCh38/hg38 17p13.1(chr17:6958978-8335684)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052457]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052457]|See cases [RCV000052457] Chr17:6958978..8335684 [GRCh38]
Chr17:6862297..8239002 [GRCh37]
Chr17:6803021..8179727 [NCBI36]
Chr17:17p13.1
pathogenic
GRCh38/hg38 17p13.2-13.1(chr17:6307904-8842949)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053407]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053407]|See cases [RCV000053407] Chr17:6307904..8842949 [GRCh38]
Chr17:6211224..8746266 [GRCh37]
Chr17:6151948..8686991 [NCBI36]
Chr17:17p13.2-13.1
pathogenic
GRCh38/hg38 17p13.1(chr17:7478195-8435524)x1 copy number loss See cases [RCV000053426] Chr17:7478195..8435524 [GRCh38]
Chr17:7381514..8338842 [GRCh37]
Chr17:7322238..8279567 [NCBI36]
Chr17:17p13.1
pathogenic
GRCh38/hg38 17p13.2-12(chr17:5732953-12095349)x3 copy number gain See cases [RCV000134851] Chr17:5732953..12095349 [GRCh38]
Chr17:5636273..11998666 [GRCh37]
Chr17:5576997..11939391 [NCBI36]
Chr17:17p13.2-12
pathogenic
GRCh38/hg38 17p13.3-13.1(chr17:162016-7697012)x1 copy number loss See cases [RCV000138214] Chr17:162016..7697012 [GRCh38]
Chr17:45835..7600330 [GRCh37]
Chr17:11807..7541055 [NCBI36]
Chr17:17p13.3-13.1
pathogenic
GRCh38/hg38 17p13.2-13.1(chr17:6361393-7750863)x3 copy number gain See cases [RCV000138220] Chr17:6361393..7750863 [GRCh38]
Chr17:6264713..7654181 [GRCh37]
Chr17:6205437..7594906 [NCBI36]
Chr17:17p13.2-13.1
likely pathogenic
GRCh38/hg38 17p13.3-12(chr17:162016-12343901)x3 copy number gain See cases [RCV000138531] Chr17:162016..12343901 [GRCh38]
Chr17:45835..12247218 [GRCh37]
Chr17:11807..12187943 [NCBI36]
Chr17:17p13.3-12
pathogenic
GRCh38/hg38 17p13.1(chr17:7544902-7670581)x3 copy number gain See cases [RCV000139519] Chr17:7544902..7670581 [GRCh38]
Chr17:7448219..7573899 [GRCh37]
Chr17:7388943..7514624 [NCBI36]
Chr17:17p13.1
uncertain significance
GRCh38/hg38 17p13.3-12(chr17:150732-14764202)x3 copy number gain See cases [RCV000142236] Chr17:150732..14764202 [GRCh38]
Chr17:525..14667519 [GRCh37]
Chr17:525..14608244 [NCBI36]
Chr17:17p13.3-12
pathogenic
1 to 10 of 93 rows

Predicted Target Of
Summary Value
Count of predictions:4672
Count of miRNA genes:806
Interacting mature miRNAs:960
Transcripts:ENST00000340624, ENST00000380450, ENST00000416273, ENST00000441599, ENST00000570353, ENST00000570527, ENST00000570547, ENST00000571153, ENST00000572182, ENST00000572262, ENST00000574539, ENST00000575314, ENST00000575618, ENST00000575729, ENST00000575903, ENST00000576152, ENST00000576478, ENST00000576728, ENST00000576747, ENST00000576830
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 106 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
597095573GWAS1191647_Hsex hormone-binding globulin measurement QTL GWAS1191647 (human)3e-2579sex hormone-binding globulin measurement1776286477628648Human
407110720GWAS759696_Hwaist-hip ratio QTL GWAS759696 (human)5e-18waist-hip ratiowaist to hip ratio (WHR) (CMO:0000020)1776286477628648Human
597036177GWAS1132251_Hheel bone mineral density QTL GWAS1132251 (human)1e-14heel bone mineral densitybone mineral density (CMO:0001226)1776313607631361Human
406938696GWAS587672_Hblood protein measurement QTL GWAS587672 (human)1e-111blood protein amount (VT:0005416)blood protein measurement (CMO:0000028)1776286477628648Human
597278611GWAS1374685_Hsex hormone-binding globulin measurement QTL GWAS1374685 (human)1e-300sex hormone-binding globulin measurement1776185977618598Human
406959951GWAS608927_Hpulse pressure measurement QTL GWAS608927 (human)0.0000002pulse pressure measurementpulse pressure (CMO:0000292)1776246287624629Human
407389784GWAS1038760_Hobsolete_red blood cell distribution width QTL GWAS1038760 (human)7e-09obsolete_red blood cell distribution width1776297077629708Human
597337994GWAS1434068_Hpositive regulation of ovulation QTL GWAS1434068 (human)0.000009positive regulation of ovulation1776301057630106Human
597106823GWAS1202897_Htestosterone measurement QTL GWAS1202897 (human)7e-286testosterone measurementserum testosterone level (CMO:0000568)1776313607631361Human
597409674GWAS1505748_Hmetabolite measurement QTL GWAS1505748 (human)7e-33metabolite measurement1776265847626585Human

1 to 10 of 106 rows
SHGC-35513  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37177,536,558 - 7,536,684UniSTSGRCh37
Build 36177,477,283 - 7,477,409RGDNCBI36
Celera177,562,975 - 7,563,101RGD
Cytogenetic Map17p13-p12UniSTS
HuRef177,430,564 - 7,430,690UniSTS
Stanford-G3 RH Map17451.0UniSTS
Whitehead-RH Map1764.1UniSTS
NCBI RH Map17205.1UniSTS
GeneMap99-G3 RH Map17451.0UniSTS
RH66154  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37177,529,598 - 7,529,739UniSTSGRCh37
Build 36177,470,323 - 7,470,464RGDNCBI36
Celera177,556,014 - 7,556,155RGD
Cytogenetic Map17p13.1UniSTS
Cytogenetic Map17p13-p12UniSTS
HuRef177,423,628 - 7,423,769UniSTS
PMC150924P1  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37177,534,457 - 7,534,739UniSTSGRCh37
Build 36177,475,182 - 7,475,464RGDNCBI36
Celera177,560,874 - 7,561,156RGD
Cytogenetic Map17p13-p12UniSTS
HuRef177,428,463 - 7,428,745UniSTS
RH18329  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37177,529,621 - 7,529,752UniSTSGRCh37
Build 36177,470,346 - 7,470,477RGDNCBI36
Celera177,556,037 - 7,556,168RGD
Cytogenetic Map17p13.1UniSTS
Cytogenetic Map17p13-p12UniSTS
HuRef177,423,651 - 7,423,782UniSTS
GeneMap99-GB4 RH Map1748.53UniSTS
SHGC-166  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37177,529,595 - 7,529,745UniSTSGRCh37
Build 36177,470,320 - 7,470,470RGDNCBI36
Celera177,556,011 - 7,556,161RGD
Cytogenetic Map17p13.1UniSTS
Cytogenetic Map17p13-p12UniSTS
HuRef177,423,625 - 7,423,775UniSTS
TNG Radiation Hybrid Map173956.0UniSTS
GeneMap99-G3 RH Map17451.0UniSTS




adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
1201 2406 2737 2178 4899 1723 2328 4 621 1458 464 2223 6712 5907 48 3707 841 1726 1595 169


1 to 30 of 47 rows
RefSeq Transcripts NG_011981 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001040 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001146279 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001146280 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001146281 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001289113 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001289114 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001289115 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001289116 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC007421 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK302603 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC069597 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC101785 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC112186 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CD013955 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CD013957 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CD013958 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471108 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068261 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU352656 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU352657 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU352658 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU352659 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU352660 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU352661 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU352662 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU352663 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU352664 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU352665 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU352666 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
1 to 30 of 47 rows

Ensembl Acc Id: ENST00000340624   ⟹   ENSP00000345675
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl177,627,969 - 7,633,382 (+)Ensembl
Ensembl Acc Id: ENST00000380450   ⟹   ENSP00000369816
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl177,630,135 - 7,633,372 (+)Ensembl
Ensembl Acc Id: ENST00000416273   ⟹   ENSP00000388867
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl177,630,152 - 7,633,372 (+)Ensembl
Ensembl Acc Id: ENST00000441599   ⟹   ENSP00000393426
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl177,630,094 - 7,633,382 (+)Ensembl
Ensembl Acc Id: ENST00000570353   ⟹   ENSP00000458199
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl177,630,152 - 7,633,372 (+)Ensembl
Ensembl Acc Id: ENST00000570527   ⟹   ENSP00000461162
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl177,630,152 - 7,633,372 (+)Ensembl
Ensembl Acc Id: ENST00000570547   ⟹   ENSP00000458875
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl177,614,064 - 7,633,354 (+)Ensembl
Ensembl Acc Id: ENST00000571153   ⟹   ENSP00000458858
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl177,630,254 - 7,633,354 (+)Ensembl
Ensembl Acc Id: ENST00000572182   ⟹   ENSP00000458816
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl177,614,064 - 7,633,354 (+)Ensembl
Ensembl Acc Id: ENST00000572262   ⟹   ENSP00000459999
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl177,614,064 - 7,633,354 (+)Ensembl
Ensembl Acc Id: ENST00000574539   ⟹   ENSP00000458181
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl177,614,064 - 7,633,354 (+)Ensembl
Ensembl Acc Id: ENST00000575314   ⟹   ENSP00000458559
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl177,614,064 - 7,633,354 (+)Ensembl
Ensembl Acc Id: ENST00000575618   ⟹   ENSP00000459826
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl177,630,254 - 7,633,354 (+)Ensembl
Ensembl Acc Id: ENST00000575729   ⟹   ENSP00000458719
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl177,627,969 - 7,631,260 (+)Ensembl
Ensembl Acc Id: ENST00000575903   ⟹   ENSP00000458973
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl177,630,152 - 7,633,372 (+)Ensembl
Ensembl Acc Id: ENST00000576152   ⟹   ENSP00000461743
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl177,630,254 - 7,633,354 (+)Ensembl
Ensembl Acc Id: ENST00000576478   ⟹   ENSP00000461133
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl177,614,064 - 7,633,354 (+)Ensembl
Ensembl Acc Id: ENST00000576728   ⟹   ENSP00000459620
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl177,614,064 - 7,633,354 (+)Ensembl
Ensembl Acc Id: ENST00000576747
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl177,631,309 - 7,632,057 (+)Ensembl
Ensembl Acc Id: ENST00000576830   ⟹   ENSP00000460219
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl177,630,254 - 7,633,354 (+)Ensembl
Ensembl Acc Id: ENST00000624152
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl177,613,946 - 7,614,109 (+)Ensembl
RefSeq Acc Id: NM_001040   ⟹   NP_001031
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38177,630,135 - 7,633,372 (+)NCBI
GRCh37177,517,382 - 7,536,700 (+)ENTREZGENE
Build 36177,474,216 - 7,477,395 (+)NCBI Archive
HuRef177,411,426 - 7,430,708 (+)NCBI
CHM1_1177,542,593 - 7,545,882 (+)NCBI
T2T-CHM13v2.0177,534,326 - 7,537,563 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001146279   ⟹   NP_001139751
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38177,630,135 - 7,633,372 (+)NCBI
GRCh37177,517,382 - 7,536,700 (+)ENTREZGENE
HuRef177,411,426 - 7,430,708 (+)NCBI
CHM1_1177,542,593 - 7,545,882 (+)NCBI
T2T-CHM13v2.0177,534,326 - 7,537,563 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001146280   ⟹   NP_001139752
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38177,630,135 - 7,633,372 (+)NCBI
GRCh37177,517,382 - 7,536,700 (+)ENTREZGENE
HuRef177,411,426 - 7,430,708 (+)NCBI
CHM1_1177,542,593 - 7,545,882 (+)NCBI
T2T-CHM13v2.0177,534,326 - 7,537,563 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001146281   ⟹   NP_001139753
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38177,630,135 - 7,633,372 (+)NCBI
GRCh37177,517,382 - 7,536,700 (+)ENTREZGENE
HuRef177,411,426 - 7,430,708 (+)NCBI
CHM1_1177,542,593 - 7,545,882 (+)NCBI
T2T-CHM13v2.0177,534,326 - 7,537,563 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001289113   ⟹   NP_001276042
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38177,627,561 - 7,633,372 (+)NCBI
HuRef177,411,426 - 7,430,708 (+)NCBI
CHM1_1177,540,468 - 7,545,882 (+)NCBI
T2T-CHM13v2.0177,531,762 - 7,537,563 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001289114   ⟹   NP_001276043
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38177,614,064 - 7,633,372 (+)NCBI
HuRef177,411,426 - 7,430,708 (+)NCBI
CHM1_1177,526,291 - 7,545,882 (+)NCBI
T2T-CHM13v2.0177,518,285 - 7,537,563 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001289115   ⟹   NP_001276044
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38177,627,561 - 7,633,372 (+)NCBI
HuRef177,411,426 - 7,430,708 (+)NCBI
CHM1_1177,540,468 - 7,545,882 (+)NCBI
T2T-CHM13v2.0177,531,762 - 7,537,563 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001289116   ⟹   NP_001276045
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38177,630,135 - 7,633,372 (+)NCBI
HuRef177,411,426 - 7,430,708 (+)NCBI
CHM1_1177,542,593 - 7,545,882 (+)NCBI
T2T-CHM13v2.0177,534,326 - 7,537,563 (+)NCBI
Sequence:
1 to 30 of 46 rows
Protein RefSeqs NP_001031 (Get FASTA)   NCBI Sequence Viewer  
  NP_001139751 (Get FASTA)   NCBI Sequence Viewer  
  NP_001139752 (Get FASTA)   NCBI Sequence Viewer  
  NP_001139753 (Get FASTA)   NCBI Sequence Viewer  
  NP_001276042 (Get FASTA)   NCBI Sequence Viewer  
  NP_001276043 (Get FASTA)   NCBI Sequence Viewer  
  NP_001276044 (Get FASTA)   NCBI Sequence Viewer  
  NP_001276045 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAC18778 (Get FASTA)   NCBI Sequence Viewer  
  AAH69597 (Get FASTA)   NCBI Sequence Viewer  
  AAI01786 (Get FASTA)   NCBI Sequence Viewer  
  AAI12187 (Get FASTA)   NCBI Sequence Viewer  
  ABY67997 (Get FASTA)   NCBI Sequence Viewer  
  ABY67998 (Get FASTA)   NCBI Sequence Viewer  
  ABY67999 (Get FASTA)   NCBI Sequence Viewer  
  ABY68000 (Get FASTA)   NCBI Sequence Viewer  
  ABY68001 (Get FASTA)   NCBI Sequence Viewer  
  ABY68002 (Get FASTA)   NCBI Sequence Viewer  
  ABY68003 (Get FASTA)   NCBI Sequence Viewer  
  ABY68004 (Get FASTA)   NCBI Sequence Viewer  
  ABY68005 (Get FASTA)   NCBI Sequence Viewer  
  ABY68006 (Get FASTA)   NCBI Sequence Viewer  
  ABY68007 (Get FASTA)   NCBI Sequence Viewer  
  ABY68008 (Get FASTA)   NCBI Sequence Viewer  
  BAG63852 (Get FASTA)   NCBI Sequence Viewer  
  CAA28987 (Get FASTA)   NCBI Sequence Viewer  
  CAA29234 (Get FASTA)   NCBI Sequence Viewer  
  CAA29309 (Get FASTA)   NCBI Sequence Viewer  
  CAA34398 (Get FASTA)   NCBI Sequence Viewer  
  CAA34399 (Get FASTA)   NCBI Sequence Viewer  
1 to 30 of 46 rows
1 to 5 of 27 rows
1 to 5 of 27 rows
RefSeq Acc Id: NP_001031   ⟸   NM_001040
- Peptide Label: isoform 1 precursor
- UniProtKB: Q3MIL0 (UniProtKB/Swiss-Prot),   Q16616 (UniProtKB/Swiss-Prot),   P14689 (UniProtKB/Swiss-Prot),   I3L1N7 (UniProtKB/Swiss-Prot),   F5H5Z8 (UniProtKB/Swiss-Prot),   E9PGW1 (UniProtKB/Swiss-Prot),   B4DYU0 (UniProtKB/Swiss-Prot),   B0FWH4 (UniProtKB/Swiss-Prot),   Q6ISD2 (UniProtKB/Swiss-Prot),   P04278 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001139752   ⟸   NM_001146280
- Peptide Label: isoform 3 precursor
- UniProtKB: P04278 (UniProtKB/Swiss-Prot),   B0FWH2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001139753   ⟸   NM_001146281
- Peptide Label: isoform 4 precursor
- UniProtKB: A0A0C4DGN2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001139751   ⟸   NM_001146279
- Peptide Label: isoform 2 precursor
- UniProtKB: P04278 (UniProtKB/Swiss-Prot),   B0FWH2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001276043   ⟸   NM_001289114
- Peptide Label: isoform 5
- UniProtKB: I3L145 (UniProtKB/TrEMBL),   I3L2X4 (UniProtKB/TrEMBL)
- Sequence:
Laminin G   Laminin G-like

Name Modeler Protein Id AA Range Protein Structure
AF-P04278-F1-model_v2 AlphaFold P04278 1-402 view protein structure

RGD ID:6794512
Promoter ID:HG_KWN:24902
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   HeLa_S3,   K562,   Lymphoblastoid
Transcripts:ENST00000340624,   ENST00000380466,   NM_133491,   NR_027462,   UC010CMV.1,   UC010CMW.1,   UC010CMX.1,   UC010CMZ.1
Position:
Human AssemblyChrPosition (strand)Source
Build 36177,471,616 - 7,472,116 (-)MPROMDB
RGD ID:7233811
Promoter ID:EPDNEW_H22650
Type:initiation region
Name:SHBG_2
Description:sex hormone binding globulin
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H22653  EPDNEW_H22654  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38177,614,032 - 7,614,092EPDNEW
RGD ID:7233813
Promoter ID:EPDNEW_H22653
Type:initiation region
Name:SHBG_3
Description:sex hormone binding globulin
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H22650  EPDNEW_H22654  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38177,627,994 - 7,628,054EPDNEW
RGD ID:7233817
Promoter ID:EPDNEW_H22654
Type:initiation region
Name:SHBG_1
Description:sex hormone binding globulin
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H22650  EPDNEW_H22653  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38177,630,135 - 7,630,195EPDNEW


1 to 40 of 66 rows
Database
Acc Id
Source(s)
COSMIC SHBG COSMIC
Ensembl Genes ENSG00000129214 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000340624 ENTREZGENE
  ENST00000380450 ENTREZGENE
  ENST00000380450.9 UniProtKB/Swiss-Prot
  ENST00000416273 ENTREZGENE
  ENST00000416273.7 UniProtKB/Swiss-Prot
  ENST00000441599 ENTREZGENE
  ENST00000441599.6 UniProtKB/Swiss-Prot
  ENST00000574539 ENTREZGENE
  ENST00000574539.5 UniProtKB/Swiss-Prot
  ENST00000575314 ENTREZGENE
  ENST00000575903 ENTREZGENE
  ENST00000575903.5 UniProtKB/Swiss-Prot
Gene3D-CATH 2.60.120.200 UniProtKB/Swiss-Prot
GTEx ENSG00000129214 GTEx
HGNC ID HGNC:10839 ENTREZGENE
Human Proteome Map SHBG Human Proteome Map
InterPro ConA-like_dom_sf UniProtKB/Swiss-Prot
  GAS-SHBG-PROS UniProtKB/Swiss-Prot
  Laminin_G UniProtKB/Swiss-Prot
KEGG Report hsa:6462 UniProtKB/Swiss-Prot
NCBI Gene 6462 ENTREZGENE
OMIM 182205 OMIM
PANTHER LAMININ G-LIKE DOMAIN-CONTAINING PROTEIN UniProtKB/Swiss-Prot
  SEX HORMONE-BINDING GLOBULIN UniProtKB/Swiss-Prot
Pfam Laminin_G_1 UniProtKB/Swiss-Prot
PharmGKB PA35745 PharmGKB
PROSITE LAM_G_DOMAIN UniProtKB/Swiss-Prot
SMART LamG UniProtKB/Swiss-Prot
Superfamily-SCOP SSF49899 UniProtKB/Swiss-Prot
UniProt A0A0C4DGN2 ENTREZGENE, UniProtKB/TrEMBL
  B0FWH2 ENTREZGENE, UniProtKB/TrEMBL
  B0FWH4 ENTREZGENE
  B0FWH5_HUMAN UniProtKB/TrEMBL
  B0FWH6_HUMAN UniProtKB/TrEMBL
  B0FWH7_HUMAN UniProtKB/TrEMBL
  B0FWH8_HUMAN UniProtKB/TrEMBL
  B4DYU0 ENTREZGENE
  E9PGW1 ENTREZGENE
1 to 40 of 66 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-04-12 SHBG  sex hormone binding globulin  SHBG  sex hormone-binding globulin  Symbol and/or name change 5135510 APPROVED