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Gene: MT2A (metallothionein 2A) Homo sapiens
Symbol: MT2A
Name: metallothionein 2A
Description: Exhibits drug binding activity and zinc ion binding activity. Involved in cellular response to cytokine stimulus; cellular response to drug; and cellular response to zinc ion. Predicted to localize to the nucleus and perinuclear region of cytoplasm. Implicated in carotid stenosis and type 2 diabetes mellitus. Biomarker of psychotic disorder and senile cataract.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: metallothionein-2; metallothionein-2A; metallothionein-II; MT-2; MT-II; MT2
Mus musculus (house mouse) : Mt2 (metallothionein 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Mt2A (metallothionein 2A)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : LOC100986475 (metallothionein-2)
Canis lupus familiaris (dog) : MT2A (metallothionein 1H)
Sus scrofa (pig) : MT-2B (metallothionein-2A)
more info ...
Related Pseudogenes: MT2P1   MTL3P  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381656,608,584 - 56,609,497 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371656,642,478 - 56,643,409 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361655,200,012 - 55,200,896 (+)NCBINCBI36hg18NCBI36
Build 341655,200,011 - 55,200,892NCBI
Celera1641,139,964 - 41,140,895 (+)NCBI
Cytogenetic Map16q13NCBI
HuRef1642,512,001 - 42,512,932 (+)NCBIHuRef
CHM1_11658,048,948 - 58,049,879 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on MT2A
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1352146
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-10-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.