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Gene: LHCGR (luteinizing hormone/choriogonadotropin receptor) Homo sapiens
Symbol: LHCGR
Name: luteinizing hormone/choriogonadotropin receptor
Description: Exhibits luteinizing hormone receptor activity. Involved in cellular response to luteinizing hormone stimulus; cognition; and luteinizing hormone signaling pathway. Localizes to plasma membrane. Implicated in Leydig cell tumor; breast cancer; familial male-limited precocious puberty; and gonadal disease. Biomarker of granulosa cell tumor; mucinous cystadenocarcinoma; and serous cystadenocarcinoma.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: FLJ41504; HHG; hypergonadotropic hypogonadism; LCGR; LGR2; LH/CG-R; LH/CGR; LHR; LHRHR; LSH-R; lutropin-choriogonadotropic hormone receptor; lutropin/choriogonadotropin receptor; ULG5
Mus musculus (house mouse) : Lhcgr (luteinizing hormone/choriogonadotropin receptor)  MGI  Alliance
Rattus norvegicus (Norway rat) : Lhcgr (luteinizing hormone/choriogonadotropin receptor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lhcgr (luteinizing hormone/choriogonadotropin receptor)
Pan paniscus (bonobo/pygmy chimpanzee) : LHCGR (luteinizing hormone/choriogonadotropin receptor)
Canis lupus familiaris (dog) : LHCGR (luteinizing hormone/choriogonadotropin receptor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lhcgr (luteinizing hormone/choriogonadotropin receptor)
Sus scrofa (pig) : LHCGR (luteinizing hormone/choriogonadotropin receptor)
Chlorocebus sabaeus (African green monkey) : LHCGR (luteinizing hormone/choriogonadotropin receptor)
Heterocephalus glaber (naked mole-rat) : Lhcgr (luteinizing hormone/choriogonadotropin receptor)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl248,686,774 - 48,755,730 (-)EnsemblGRCh38hg38GRCh38
GRCh38248,686,774 - 48,755,724 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37248,913,913 - 48,982,880 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36248,767,417 - 48,836,367 (-)NCBINCBI36hg18NCBI36
Build 34248,825,619 - 48,894,468NCBI
Celera248,754,221 - 48,823,183 (-)NCBI
Cytogenetic Map2p16.3NCBI
HuRef248,647,284 - 48,716,442 (-)NCBIHuRef
CHM1_1248,844,653 - 48,913,614 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on LHCGR
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 737217
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.