Gene: LHCGR (luteinizing hormone/choriogonadotropin receptor) Homo sapiens
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Symbol: LHCGR
Name: luteinizing hormone/choriogonadotropin receptor
Description: This gene encodes the receptor for both luteinizing hormone and choriogonadotropin. This receptor belongs to the G-protein coupled receptor 1 family, and its activity is mediated by G proteins which activate adenylate cyclase. Mutations in this gene result in disorders of male secondary sexual character development, including familial male precocious puberty, also known as testotoxicosis, hypogonadotropic hypogonadism, Leydig cell adenoma with precocious puberty, and male pseudohermaphtoditism with Leydig cell hypoplasia. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: FLJ41504; HHG; hypergonadotropic hypogonadism; LCGR; LGR2; LH/CG-R; LH/CGR; LHR; LHRHR; LSH-R; lutropin-choriogonadotropic hormone receptor; lutropin/choriogonadotropin receptor; ULG5
Orthologs:
Mus musculus (house mouse) : Lhcgr (luteinizing hormone/choriogonadotropin receptor)  MGI  Alliance
Rattus norvegicus (Norway rat) : Lhcgr (luteinizing hormone/choriogonadotropin receptor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lhcgr (luteinizing hormone/choriogonadotropin receptor)
Pan paniscus (bonobo/pygmy chimpanzee) : LHCGR (luteinizing hormone/choriogonadotropin receptor)
Canis lupus familiaris (dog) : LHCGR (luteinizing hormone/choriogonadotropin receptor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lhcgr (luteinizing hormone/choriogonadotropin receptor)
Sus scrofa (pig) : LHCGR (luteinizing hormone/choriogonadotropin receptor)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38248,686,774 - 48,755,741 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37248,913,913 - 48,982,880 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36248,767,417 - 48,836,367 (-)NCBINCBI36hg18NCBI36
Build 34248,825,619 - 48,894,468NCBI
Celera248,754,221 - 48,823,183 (-)NCBI
Cytogenetic Map2p16.3NCBI
HuRef248,647,284 - 48,716,442 (-)NCBIHuRef
CHM1_1248,844,653 - 48,913,614 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on LHCGR
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 737217
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2019-06-11
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.