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Gene: NRDC (nardilysin convertase) Homo sapiens
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Symbol: NRDC
Name: nardilysin convertase
Description: Predicted to have epidermal growth factor binding activity. Involved in positive regulation of membrane protein ectodomain proteolysis and regulation of endopeptidase activity. Localizes to the mitochondrion.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: hNRD1; hNRD2; N-arginine dibasic convertase; nardilysin; nardilysin (N-arginine dibasic convertase); NRD convertase; NRD-C; NRD1
Orthologs:
Mus musculus (house mouse) : Nrd1 (nardilysin, N-arginine dibasic convertase, NRD convertase 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Nrdc (nardilysin convertase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nrdc (nardilysin convertase)
Pan paniscus (bonobo/pygmy chimpanzee) : NRDC (nardilysin convertase)
Canis lupus familiaris (dog) : NRDC (nardilysin convertase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nrdc (nardilysin convertase)
Sus scrofa (pig) : NRDC (nardilysin convertase)
Chlorocebus sabaeus (green monkey) : NRDC (nardilysin convertase)
Heterocephalus glaber (naked mole-rat) : Nrdc (nardilysin convertase)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl151,789,191 - 51,878,937 (-)Ensembl
GRCh38151,789,192 - 51,878,937 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37152,254,864 - 52,344,609 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36152,027,452 - 52,117,197 (-)NCBINCBI36hg18NCBI36
Build 34151,966,904 - 52,056,443NCBI
Celera150,541,402 - 50,631,711 (-)NCBI
Cytogenetic Map1p32.3NCBI
HuRef150,371,501 - 50,461,746 (-)NCBIHuRef
CHM1_1152,372,212 - 52,461,925 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on NRDC
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 731928
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.