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Gene: RFX8 (RFX family member 8, lacking RFX DNA binding domain) Homo sapiens
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Symbol: RFX8
Name: RFX family member 8, lacking RFX DNA binding domain
Description: Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning and regulation of transcription by RNA polymerase II. Predicted to localize to nuclear chromatin; INTERACTS WITH aflatoxin B1; aflatoxin B2; benzo[e]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: DNA-binding protein RFX8; FLJ16242; FLJ42986; FLJ42986 protein; FLJ52890; regulatory factor X 8; regulatory factor X, 8; RFX gene family member 8, lacking RFX DNA binding domain
Orthologs:
Mus musculus (house mouse) : Rfx8 (regulatory factor X 8)  MGI  Alliance
Rattus norvegicus (Norway rat) : Rfx8 (RFX family member 8, lacking RFX DNA binding domain)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rfx8 (RFX family member 8, lacking RFX DNA binding domain)
Pan paniscus (bonobo/pygmy chimpanzee) : RFX8 (RFX family member 8, lacking RFX DNA binding domain)
Canis lupus familiaris (dog) : RFX8 (RFX family member 8, lacking RFX DNA binding domain)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rfx8 (RFX family member 8, lacking RFX DNA binding domain)
Sus scrofa (pig) : RFX8 (RFX family member 8, lacking RFX DNA binding domain)
Chlorocebus sabaeus (African green monkey) : RFX8 (RFX family member 8, lacking RFX DNA binding domain)
Heterocephalus glaber (naked mole-rat) : Rfx8 (RFX family member 8, lacking RFX DNA binding domain)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl2101,397,359 - 101,475,112 (-)EnsemblGRCh38hg38GRCh38
GRCh382101,397,344 - 101,475,179 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372102,013,823 - 102,091,165 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362101,392,873 - 101,457,169 (-)NCBINCBI36hg18NCBI36
Celera296,217,462 - 96,291,111 (-)NCBI
Cytogenetic Map2q11.2NCBI
HuRef295,777,628 - 95,854,810 (-)NCBIHuRef
CHM1_12102,017,897 - 102,095,115 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on RFX8
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2793201
Created: 2010-07-04
Species: Homo sapiens
Last Modified: 2020-06-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.