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Gene: TSPO (translocator protein) Homo sapiens
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Symbol: TSPO
Name: translocator protein
Description: Predicted to have cholesterol binding activity. Predicted to be involved in negative regulation of mitochondrion organization. Localizes to extracellular exosome.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: benzodiazepin receptor; benzodiazepine peripheral binding site; BPBS; BZRP; DBI; IBP; MBR; mDRC; mitochondrial benzodiazepine receptor; PBR; PBS; peripheral benzodiazepine receptor; peripheral-type benzodiazepine receptor; pk18; PKBS; PTBR; translocator protein (18kDa)
Orthologs:
Mus musculus (house mouse) : Tspo (translocator protein)  MGI  Alliance
Rattus norvegicus (Norway rat) : Tspo (translocator protein)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tspo (translocator protein)
Pan paniscus (bonobo/pygmy chimpanzee) : TSPO (translocator protein)
Canis lupus familiaris (dog) : TSPO (translocator protein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tspo (translocator protein)
Sus scrofa (pig) : TSPO (translocator protein)
Chlorocebus sabaeus (African green monkey) : TSPO (translocator protein)
Heterocephalus glaber (naked mole-rat) : Tspo (translocator protein)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2243,151,547 - 43,163,242 (+)EnsemblGRCh38hg38GRCh38
GRCh382243,151,559 - 43,163,242 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372243,547,520 - 43,559,248 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362241,877,479 - 41,889,192 (+)NCBINCBI36hg18NCBI36
Build 342241,872,050 - 41,883,745NCBI
Celera2227,457,910 - 27,469,623 (+)NCBI
Cytogenetic Map22q13.2NCBI
HuRef2226,505,727 - 26,517,455 (+)NCBIHuRef
CHM1_12243,507,104 - 43,518,509 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on TSPO
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 737564
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2020-07-28
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.