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Gene: JAM2 (junctional adhesion molecule 2) Homo sapiens
Symbol: JAM2
Name: junctional adhesion molecule 2
RGD ID: 1343747
Description: Exhibits integrin binding activity. Involved in several processes, including hematopoietic stem cell migration to bone marrow; leukocyte tethering or rolling; and lymphocyte aggregation. Localizes to several cellular components, including cell surface; cell-cell contact zone; and protein complex involved in cell adhesion. Implicated in basal ganglia calcification.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: C21orf43; CD322; IBGC8; JAM-2; JAM-B; JAM-IT/VE-JAM; JAMB; junctional adhesion molecule B; PRO245; vascular endothelial junction-associated molecule; VE-JAM; VEJAM
Mus musculus (house mouse) : Jam2 (junction adhesion molecule 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Jam2 (junctional adhesion molecule 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Jam2 (junctional adhesion molecule 2)
Pan paniscus (bonobo/pygmy chimpanzee) : JAM2 (junctional adhesion molecule 2)
Canis lupus familiaris (dog) : JAM2 (junctional adhesion molecule 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Jam2 (junctional adhesion molecule 2)
Sus scrofa (pig) : JAM2 (junctional adhesion molecule 2)
Chlorocebus sabaeus (African green monkey) : JAM2 (junctional adhesion molecule 2)
Heterocephalus glaber (naked mole-rat) : Jam2 (junctional adhesion molecule 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl2125,639,258 - 25,717,562 (+)EnsemblGRCh38hg38GRCh38
GRCh382125,607,550 - 25,717,562 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372127,011,594 - 27,089,874 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362125,933,460 - 26,009,106 (+)NCBINCBI36hg18NCBI36
Build 342125,933,459 - 26,009,106NCBI
Celera2112,195,003 - 12,270,650 (+)NCBI
Cytogenetic Map21q21.3NCBI
HuRef2112,414,742 - 12,493,008 (+)NCBIHuRef
CHM1_12126,572,234 - 26,650,529 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on JAM2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1343747
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-09-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.