ATF3 (activating transcription factor 3) - Rat Genome Database
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Gene: ATF3 (activating transcription factor 3) Homo sapiens
Analyze
Symbol: ATF3
Name: activating transcription factor 3
RGD ID: 735760
HGNC Page HGNC
Description: Exhibits DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; and protein dimerization activity. Involved in negative regulation of transcription by RNA polymerase II; positive regulation of TRAIL-activated apoptotic signaling pathway; and positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress. Localizes to CHOP-ATF3 complex; nucleolus; and nucleoplasm. Biomarker of prostate cancer and pulmonary tuberculosis.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ATF3deltaZip2; ATF3deltaZip2c; ATF3deltaZip3; cAMP-dependent transcription factor ATF-3; cyclic AMP-dependent transcription factor ATF-3; FLJ41705
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1212,565,334 - 212,620,777 (+)EnsemblGRCh38hg38GRCh38
GRCh381212,565,407 - 212,620,777 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371212,738,676 - 212,794,119 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361210,805,320 - 210,860,740 (+)NCBINCBI36hg18NCBI36
Build 341209,170,507 - 209,182,494NCBI
Celera1185,964,759 - 186,020,178 (+)NCBI
Cytogenetic Map1q32.3NCBI
HuRef1183,415,472 - 183,470,943 (+)NCBIHuRef
CHM1_11214,011,558 - 214,066,986 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-anisomycin  (EXP)
(-)-citrinin  (EXP)
(-)-demecolcine  (EXP)
(-)-epigallocatechin 3-gallate  (EXP)
(E)-cinnamyl alcohol  (EXP)
(S)-amphetamine  (ISO)
(S)-nicotine  (EXP,ISO)
1,1-dichloroethene  (ISO)
1,2,4-trimethylbenzene  (ISO)
1,2-dimethylhydrazine  (ISO)
1,3-benzothiazole-2-thiol  (EXP)
1,4-dithiothreitol  (EXP)
1,4-phenylenediamine  (EXP)
1-(4-methoxybenzyl)-3-(5-nitro-1,3-thiazol-2-yl)urea  (EXP)
1-chloro-2,4-dinitrobenzene  (EXP)
1-fluoro-2,4-dinitrobenzene  (EXP)
1-naphthyl isothiocyanate  (ISO)
15-acetyldeoxynivalenol  (EXP)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
17beta-hydroxy-17-methylestra-4,9,11-trien-3-one  (EXP)
17beta-hydroxy-5alpha-androstan-3-one  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrobenzenesulfonic acid  (ISO)
2,4-dinitrotoluene  (ISO)
2-amino-2-deoxy-D-glucopyranose  (ISO)
2-bromo-2-(bromomethyl)pentanedinitrile  (EXP)
2-butoxyethanol  (ISO)
2-Ethylhexyl acrylate  (EXP)
2-hydroxypropanoic acid  (EXP)
2-nitrofluorene  (ISO)
3,3',4',5-tetrachlorosalicylanilide  (EXP)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,3'-diindolylmethane  (EXP)
3,4-dichloroaniline  (EXP)
3-phenylprop-2-enal  (EXP)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-(ethoxymethylene)-2-phenyloxazol-5-one  (EXP)
4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one  (ISO)
4-hydroxynon-2-enal  (EXP)
4-hydroxyphenyl retinamide  (EXP,ISO)
4-nitrobenzyl bromide  (EXP)
5-aza-2'-deoxycytidine  (EXP)
5-fluorouracil  (EXP)
6-propyl-2-thiouracil  (ISO)
abietic acid  (EXP)
acetamide  (ISO)
acrolein  (EXP,ISO)
acrylamide  (ISO)
adefovir pivoxil  (EXP)
afimoxifene  (EXP)
aflatoxin B1  (EXP,ISO)
aldehydo-D-glucosamine  (ISO)
all-trans-retinoic acid  (EXP,ISO)
Aloe emodin  (EXP)
alpha-hexylcinnamaldehyde  (EXP)
amiodarone  (EXP)
amitriptyline  (ISO)
ammonium chloride  (ISO)
amphetamine  (ISO)
amphibole asbestos  (EXP)
aniline  (EXP)
anthra[1,9-cd]pyrazol-6(2H)-one  (EXP,ISO)
antimycin A  (ISO)
antirheumatic drug  (EXP)
arachidonic acid  (EXP)
Aroclor 1254  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (EXP)
asbestos  (EXP)
benzene  (EXP)
benzene-1,2,4-triol  (EXP)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (EXP)
benzo[b]fluoranthene  (EXP)
benzo[e]pyrene  (EXP)
benzyl benzoate  (EXP)
Benzyl salicylate  (EXP)
benzylpenicillin  (EXP)
beta-D-glucosamine  (ISO)
bicalutamide  (EXP)
bilirubin IXalpha  (EXP)
bis(2-chloroethyl) sulfide  (EXP,ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol A diglycidyl ether  (EXP)
bisphenol F  (ISO)
boron nitride  (EXP)
bortezomib  (EXP,ISO)
bromocriptine  (EXP)
butanal  (EXP)
cadmium atom  (EXP)
cadmium dichloride  (EXP,ISO)
cadmium sulfate  (EXP)
calcitriol  (EXP)
cannabidiol  (ISO)
capsaicin  (EXP)
carbamazepine  (EXP)
carbon nanotube  (EXP,ISO)
cefaloridine  (ISO)
celastrol  (EXP)
chloroacetaldehyde  (EXP)
chloropicrin  (EXP)
chloroprene  (ISO)
choline  (ISO)
chromium(6+)  (EXP)
cidofovir anhydrous  (EXP)
cinnamyl alcohol  (EXP)
cisplatin  (EXP)
clodronic acid  (EXP)
clofibrate  (ISO)
clotrimazole  (EXP)
cobalt dichloride  (EXP,ISO)
cocaine  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
copper(II) sulfate  (EXP)
coumestrol  (EXP)
crocidolite asbestos  (EXP)
crotonaldehyde  (EXP)
CU-O LINKAGE  (EXP)
curcumin  (EXP)
cycloheximide  (ISO)
cyclosporin A  (EXP,ISO)
cylindrospermopsin  (EXP)
cytarabine  (EXP)
DDE  (EXP)
DDT  (ISO)
deoxynivalenol  (EXP,ISO)
dexamethasone  (ISO)
diallyl disulfide  (EXP)
diarsenic trioxide  (EXP)
dibenz[a,h]anthracene  (EXP)
dibenzo[a,l]pyrene  (EXP)
dibutyl phthalate  (ISO)
dichloroacetic acid  (ISO)
dieldrin  (EXP)
diethylenetriamine  (EXP)
diethylstilbestrol  (ISO)
dimethyl sulfoxide  (ISO)
dinophysistoxin 1  (EXP)
dioxygen  (EXP,ISO)
diquat  (EXP)
disulfiram  (EXP)
diuron  (EXP)
dodecan-1-ol  (EXP)
dorsomorphin  (EXP)
doxorubicin  (EXP,ISO)
echinacoside  (EXP)
ellagic acid  (EXP)
endosulfan  (ISO)
Enterolactone  (EXP)
ethanol  (EXP,ISO)
ethyl methanesulfonate  (EXP)
ethylene glycol dimethacrylate  (EXP)
ethylenediamine  (EXP)
eugenol  (EXP)
farnesol  (EXP)
fenamidone  (ISO)
fenofibrate  (EXP,ISO)
fenvalerate  (ISO)
ferric oxide  (ISO)
fluoranthene  (ISO)
flutamide  (ISO)
folic acid  (EXP,ISO)
formaldehyde  (EXP)
furan  (ISO)
gedunin  (EXP)
gemcitabine  (EXP)
genistein  (EXP)
gentamycin  (ISO)
geraniol  (EXP)
glycidol  (ISO)
glyoxal  (EXP)
graphite  (ISO)
hydralazine  (ISO)
hydrogen peroxide  (EXP)
hydroquinone  (EXP)
imidurea  (EXP)
indole-3-methanol  (ISO)
irinotecan  (EXP)
isoeugenol  (EXP)
isoprenaline  (ISO)
L-1,4-dithiothreitol  (EXP)
L-ascorbic acid  (EXP)
L-methionine  (ISO)
lamivudine  (EXP)
leflunomide  (EXP)
limonene  (EXP)
lipopolysaccharide  (EXP,ISO)
menadione  (EXP)
mercury dibromide  (EXP)
mercury dichloride  (ISO)
metacetamol  (ISO)
metformin  (ISO)
methamphetamine  (ISO)
methapyrilene  (EXP,ISO)
methotrexate  (EXP,ISO)
methyl methanesulfonate  (EXP)
methylisothiazolinone  (EXP)
methylmercury chloride  (EXP,ISO)
methylparaben  (EXP)
methylseleninic acid  (EXP)
mifepristone  (EXP)
minocycline  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
motexafin gadolinium  (EXP)
muramyl dipeptide  (EXP)
N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide  (EXP,ISO)
N-acetyl-L-cysteine  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
N-methyl-4-phenylpyridinium  (EXP)
N-nitrosodiethylamine  (ISO)
N-nitrosodimethylamine  (ISO)
N-Nitrosopyrrolidine  (EXP)
N1'-[2-[[5-[(dimethylamino)methyl]-2-furanyl]methylthio]ethyl]-N1-methyl-2-nitroethene-1,1-diamine  (ISO)
naphthalene  (ISO)
naphthalenes  (ISO)
nelfinavir  (EXP)
nickel atom  (EXP)
nickel dichloride  (EXP,ISO)
nickel subsulfide  (ISO)
nickel sulfate  (EXP)
Niclosamide  (EXP)
nicotine  (EXP,ISO)
Nivalenol  (EXP)
nonivamide  (EXP)
ochratoxin A  (EXP)
octanoic acid  (EXP)
orphenadrine  (ISO)
oxaliplatin  (ISO)
ozone  (ISO)
p-chloromercuribenzoic acid  (EXP)
paclitaxel  (ISO)
panobinostat  (EXP)
paracetamol  (EXP,ISO)
paraquat  (ISO)
patulin  (EXP)
pentachlorophenol  (EXP)
pentanal  (EXP)
perfluorodecanoic acid  (EXP)
perfluorododecanoic acid  (EXP,ISO)
perfluorononanoic acid  (EXP)
perfluorooctanoic acid  (EXP,ISO)
perfluoroundecanoic acid  (ISO)
phenformin  (ISO)
phenobarbital  (EXP,ISO)
phenyl benzoate  (EXP)
phenylmercury acetate  (EXP)
phlorizin  (ISO)
phosgene  (ISO)
pioglitazone  (EXP)
piperonyl butoxide  (ISO)
pirinixic acid  (ISO)
piroxicam  (EXP)
poly(I:C)  (EXP)
potassium bromate  (ISO)
potassium chromate  (EXP)
potassium dichromate  (EXP)
pregnenolone 16alpha-carbonitrile  (ISO)
progesterone  (EXP)
propiconazole  (ISO)
prostaglandin E2  (EXP)
pyrazinecarboxamide  (ISO)
quartz  (EXP)
quercetin  (EXP)
rac-lactic acid  (EXP)
raloxifene  (EXP)
ranitidine  (ISO)
reactive oxygen species  (EXP)
resorcinol  (EXP)
resveratrol  (EXP,ISO)
rotenone  (ISO)
S-adenosyl-L-methioninate  (ISO)
S-adenosyl-L-methionine  (ISO)
Salinomycin  (EXP)
salubrinal  (EXP)
SB 203580  (EXP,ISO)
SB 431542  (EXP)
SC-58125  (EXP)
SCH 23390  (ISO)
serpentine asbestos  (EXP)
Shikonin  (ISO)
silicon dioxide  (EXP,ISO)
silver atom  (EXP)
silver(0)  (EXP)
simvastatin  (EXP)
sirolimus  (EXP)
sodium arsenite  (EXP,ISO)
sodium dichromate  (ISO)
sodium dodecyl sulfate  (EXP)
Soman  (ISO)
styrene  (ISO)
sulindac  (EXP)
sulindac sulfide  (EXP)
sunitinib  (EXP)
tacrolimus hydrate  (ISO)
tamoxifen  (EXP)
tert-butyl hydroperoxide  (EXP)
testosterone  (EXP,ISO)
tetrachloromethane  (ISO)
thalidomide  (EXP)
thapsigargin  (EXP,ISO)
thimerosal  (EXP)
thioacetamide  (ISO)
thiram  (EXP)
titanium dioxide  (ISO)
topotecan  (ISO)
torcetrapib  (EXP)
trans-isoeugenol  (EXP)
triacsin C  (EXP)
tributylstannane  (ISO)
Tributyltin oxide  (EXP,ISO)
trichloroethene  (ISO)
trichostatin A  (EXP)
trimethyltin  (ISO)
troglitazone  (EXP,ISO)
tunicamycin  (EXP,ISO)
undecanal  (EXP)
undecane  (ISO)
urethane  (EXP)
valproic acid  (EXP,ISO)
vinclozolin  (ISO)
vincristine  (EXP)
vitamin E  (EXP)
vorinostat  (EXP)
zidovudine  (EXP)
zinc acetate  (EXP)
zinc atom  (EXP)
zinc(0)  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
CHOP-ATF3 complex  (IDA)
chromatin  (ISA)
nucleolus  (IDA)
nucleoplasm  (IDA,TAS)
nucleus  (IBA,IDA,IEA)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:1827203   PMID:2516827   PMID:7515060   PMID:7692236   PMID:8152431   PMID:8576171   PMID:8622660   PMID:8649793   PMID:10327051   PMID:11375399   PMID:11726207   PMID:11792711  
PMID:11810028   PMID:12034827   PMID:12161427   PMID:12372430   PMID:12386811   PMID:12392999   PMID:12477932   PMID:12718878   PMID:12805554   PMID:12833146   PMID:12881527   PMID:14667575  
PMID:14673171   PMID:14685163   PMID:14702039   PMID:14759258   PMID:15280448   PMID:15385533   PMID:15489334   PMID:15670751   PMID:15933712   PMID:16079301   PMID:16109718   PMID:16169070  
PMID:16263788   PMID:16286461   PMID:16291753   PMID:16300731   PMID:16306208   PMID:16344560   PMID:16484797   PMID:16613840   PMID:16912181   PMID:16989641   PMID:17014422   PMID:17042743  
PMID:17102133   PMID:17178897   PMID:17295236   PMID:17437852   PMID:17599613   PMID:17952119   PMID:18001166   PMID:18029348   PMID:18192274   PMID:18235102   PMID:18255255   PMID:18308734  
PMID:18426833   PMID:18644986   PMID:18692824   PMID:18755691   PMID:18802113   PMID:18922905   PMID:19050264   PMID:19060337   PMID:19136462   PMID:19164757   PMID:19219066   PMID:19274049  
PMID:19582787   PMID:19647793   PMID:19913121   PMID:19932681   PMID:20002170   PMID:20102225   PMID:20110283   PMID:20167600   PMID:20180416   PMID:20211142   PMID:20215396   PMID:20304822  
PMID:20351107   PMID:20360311   PMID:20398657   PMID:20413626   PMID:20423458   PMID:20485437   PMID:20581861   PMID:20592017   PMID:20628086   PMID:20696134   PMID:20930144   PMID:21061913  
PMID:21129190   PMID:21191795   PMID:21294679   PMID:21300803   PMID:21315420   PMID:21324310   PMID:21414204   PMID:21421043   PMID:21451046   PMID:21454613   PMID:21467165   PMID:21495874  
PMID:21514952   PMID:21554132   PMID:21593605   PMID:21629765   PMID:21645504   PMID:21668942   PMID:21801305   PMID:21821004   PMID:21844328   PMID:21873635   PMID:21900211   PMID:21927023  
PMID:21986529   PMID:22046379   PMID:22179317   PMID:22347845   PMID:22475484   PMID:22485215   PMID:22665497   PMID:22753726   PMID:22764884   PMID:22768301   PMID:22851689   PMID:22939624  
PMID:22978410   PMID:22989952   PMID:22991139   PMID:23002211   PMID:23088992   PMID:23187734   PMID:23269699   PMID:23455924   PMID:23536558   PMID:23560949   PMID:23591848   PMID:23648135  
PMID:23661758   PMID:23706953   PMID:23733932   PMID:23868936   PMID:23884832   PMID:23921126   PMID:24098051   PMID:24133584   PMID:24420912   PMID:24460316   PMID:24469490   PMID:24509533  
PMID:24554706   PMID:24600036   PMID:24742347   PMID:24859834   PMID:24906227   PMID:24939851   PMID:24952347   PMID:24999758   PMID:25074928   PMID:25096061   PMID:25122760   PMID:25149542  
PMID:25150595   PMID:25180886   PMID:25189785   PMID:25268131   PMID:25380580   PMID:25400120   PMID:25447816   PMID:25521189   PMID:25589515   PMID:25609649   PMID:25814554   PMID:25816118  
PMID:25865756   PMID:25872784   PMID:25931127   PMID:26051724   PMID:26264872   PMID:26305977   PMID:26412238   PMID:26418018   PMID:26496610   PMID:26709509   PMID:26747248   PMID:26850942  
PMID:26851004   PMID:26994140   PMID:27043582   PMID:27050071   PMID:27087439   PMID:27107012   PMID:27196751   PMID:27659012   PMID:27780541   PMID:27883358   PMID:27902686   PMID:27956552  
PMID:28061889   PMID:28185985   PMID:28239957   PMID:28365312   PMID:28402947   PMID:28473536   PMID:28514442   PMID:28577574   PMID:28765281   PMID:28803237   PMID:28947613   PMID:29038896  
PMID:29102675   PMID:29117863   PMID:29225035   PMID:29363258   PMID:29378244   PMID:29413899   PMID:29534690   PMID:29605296   PMID:29656893   PMID:29670287   PMID:29716766   PMID:29886035  
PMID:29966001   PMID:29997244   PMID:30055801   PMID:30076901   PMID:30117642   PMID:30144543   PMID:30302023   PMID:30376856   PMID:30381822   PMID:30415952   PMID:30535500   PMID:30544543  
PMID:30648816   PMID:30804502   PMID:30833792   PMID:31176573   PMID:31220582   PMID:31356870   PMID:31375561   PMID:31389577   PMID:31467278   PMID:31546162   PMID:31642559   PMID:31796886  
PMID:31841185   PMID:31980658   PMID:32093223   PMID:32119176   PMID:32183950   PMID:32184357   PMID:32814053   PMID:32911434  


Genomics

Comparative Map Data
ATF3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1212,565,334 - 212,620,777 (+)EnsemblGRCh38hg38GRCh38
GRCh381212,565,407 - 212,620,777 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371212,738,676 - 212,794,119 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361210,805,320 - 210,860,740 (+)NCBINCBI36hg18NCBI36
Build 341209,170,507 - 209,182,494NCBI
Celera1185,964,759 - 186,020,178 (+)NCBI
Cytogenetic Map1q32.3NCBI
HuRef1183,415,472 - 183,470,943 (+)NCBIHuRef
CHM1_11214,011,558 - 214,066,986 (+)NCBICHM1_1
Atf3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391190,902,493 - 190,915,530 (-)NCBIGRCm39mm39
GRCm381191,170,296 - 191,183,333 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1191,170,296 - 191,218,039 (-)EnsemblGRCm38mm10GRCm38
MGSCv371192,994,175 - 193,007,212 (-)NCBIGRCm37mm9NCBIm37
MGSCv361192,870,911 - 192,883,948 (-)NCBImm8
Celera1198,095,832 - 198,108,890 (-)NCBICelera
Cytogenetic Map1H6NCBI
cM Map196.28NCBI
Atf3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.013109,817,892 - 109,849,632 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl13109,817,728 - 109,849,632 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.013114,411,692 - 114,443,432 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.413107,191,622 - 107,223,850 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.113107,380,725 - 107,412,954 (-)NCBI
Celera13102,216,359 - 102,219,172 (-)NCBICelera
Cytogenetic Map13q27NCBI
RH 3.4 Map13723.4RGD
Atf3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554064,875,613 - 4,889,242 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554064,875,672 - 4,889,173 (-)NCBIChiLan1.0ChiLan1.0
ATF3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11193,036,704 - 193,049,148 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1193,036,793 - 193,049,150 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01188,176,728 - 188,188,842 (+)NCBIMhudiblu_PPA_v0panPan3
ATF3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl710,782,064 - 10,794,163 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1710,784,445 - 10,795,285 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Atf3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_004936557909,302 - 922,619 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ATF3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9130,770,428 - 130,787,462 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19130,772,259 - 130,829,678 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29143,690,544 - 143,703,886 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ATF3
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12516,910,312 - 16,922,598 (-)NCBI
Atf3
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462477118,009,111 - 18,060,796 (+)NCBI

Position Markers
D1S1667  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371212,770,634 - 212,770,832UniSTSGRCh37
Build 361210,837,257 - 210,837,455RGDNCBI36
Celera1185,996,695 - 185,996,893RGD
Cytogenetic Map1q32.3UniSTS
HuRef1183,447,435 - 183,447,629UniSTS
Marshfield Genetic Map1231.5RGD
Marshfield Genetic Map1231.5UniSTS
deCODE Assembly Map1215.87UniSTS
Whitehead-YAC Contig Map1 UniSTS
SHGC-76330  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371212,793,800 - 212,793,973UniSTSGRCh37
Build 361210,860,423 - 210,860,596RGDNCBI36
Celera1186,019,861 - 186,020,034RGD
Cytogenetic Map1q32.3UniSTS
HuRef1183,470,624 - 183,470,797UniSTS
TNG Radiation Hybrid Map1104725.0UniSTS
GeneMap99-GB4 RH Map1696.94UniSTS
NCBI RH Map11879.8UniSTS
RH69028  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375179,041,305 - 179,041,537UniSTSGRCh37
GRCh371212,763,415 - 212,763,645UniSTSGRCh37
Build 361210,830,038 - 210,830,268RGDNCBI36
Celera5174,670,272 - 174,670,505UniSTS
Celera1185,989,478 - 185,989,708RGD
Cytogenetic Map5q35.3UniSTS
Cytogenetic Map1q32.3UniSTS
HuRef5173,768,232 - 173,768,465UniSTS
HuRef1183,440,218 - 183,440,448UniSTS
PMC117192P1  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371212,792,388 - 212,792,593UniSTSGRCh37
Build 361210,859,011 - 210,859,216RGDNCBI36
Celera1186,018,449 - 186,018,654RGD
Cytogenetic Map1q32.3UniSTS
HuRef1183,469,212 - 183,469,417UniSTS
AL009578  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371212,790,499 - 212,790,649UniSTSGRCh37
Build 361210,857,122 - 210,857,272RGDNCBI36
Celera1186,016,562 - 186,016,712RGD
Cytogenetic Map1q32.3UniSTS
HuRef1183,467,325 - 183,467,475UniSTS
D1S3565  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371212,778,997 - 212,779,164UniSTSGRCh37
Build 361210,845,620 - 210,845,787RGDNCBI36
Celera1186,005,060 - 186,005,227RGD
Cytogenetic Map1q32.3UniSTS
HuRef1183,455,800 - 183,455,967UniSTS
TNG Radiation Hybrid Map1104725.0UniSTS
GeneMap99-GB4 RH Map1696.63UniSTS
NCBI RH Map11880.4UniSTS
SHGC-12563  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371212,792,917 - 212,793,258UniSTSGRCh37
Build 361210,859,540 - 210,859,881RGDNCBI36
Celera1186,018,978 - 186,019,319RGD
Cytogenetic Map1q32.3UniSTS
HuRef1183,469,741 - 183,470,082UniSTS
Stanford-G3 RH Map18281.0UniSTS
GeneMap99-G3 RH Map18237.0UniSTS
RH17630  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map1q32.3UniSTS
GeneMap99-GB4 RH Map1696.63UniSTS
NCBI RH Map11880.4UniSTS

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2742
Count of miRNA genes:911
Interacting mature miRNAs:1079
Transcripts:ENST00000336937, ENST00000341491, ENST00000366981, ENST00000366983, ENST00000366985, ENST00000366987, ENST00000464547, ENST00000465155, ENST00000492118
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High 8 8 4 9 2 4 12 2 2
Medium 1658 2146 1338 484 940 358 3668 1090 1573 303 912 1454 139 1 1168 2232 6 2
Low 772 597 383 140 749 107 680 1104 2158 116 542 146 36 34 554
Below cutoff 1 239 1 261 1 3 2 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NG_029871 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001030287 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001040619 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001206484 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001206486 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001206488 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001674 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005273146 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011509579 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001737203 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB066566 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB078026 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB078027 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB078028 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB209032 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB291910 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC092803 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI492228 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI949953 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK123699 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK125255 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK294296 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK312998 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL560585 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL590648 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL606913 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AU135799 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY313926 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY313927 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY426987 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC006322 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BI524020 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BI819383 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BT006996 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CD638624 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CD641946 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CD742713 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471100 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR450334 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DA589280 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DA691940 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DB197400 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KT583928 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L19871 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U37542 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000336937   ⟹   ENSP00000336908
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1212,615,022 - 212,619,266 (+)Ensembl
RefSeq Acc Id: ENST00000341491   ⟹   ENSP00000344352
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1212,608,761 - 212,620,775 (+)Ensembl
RefSeq Acc Id: ENST00000366981   ⟹   ENSP00000355948
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1212,565,334 - 212,619,535 (+)Ensembl
RefSeq Acc Id: ENST00000366983   ⟹   ENSP00000355950
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1212,615,022 - 212,619,555 (+)Ensembl
RefSeq Acc Id: ENST00000366985   ⟹   ENSP00000355952
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1212,608,915 - 212,619,611 (+)Ensembl
RefSeq Acc Id: ENST00000366987   ⟹   ENSP00000355954
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1212,565,334 - 212,620,772 (+)Ensembl
RefSeq Acc Id: ENST00000464547   ⟹   ENSP00000432208
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1212,615,022 - 212,619,555 (+)Ensembl
RefSeq Acc Id: ENST00000465155
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1212,608,670 - 212,619,247 (+)Ensembl
RefSeq Acc Id: ENST00000492118
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1212,613,436 - 212,620,777 (+)Ensembl
RefSeq Acc Id: ENST00000613104   ⟹   ENSP00000480606
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1212,615,178 - 212,619,746 (+)Ensembl
RefSeq Acc Id: ENST00000613954   ⟹   ENSP00000483576
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1212,608,628 - 212,620,772 (+)Ensembl
RefSeq Acc Id: NM_001030287   ⟹   NP_001025458
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381212,565,407 - 212,620,775 (+)NCBI
GRCh371212,738,676 - 212,794,119 (+)NCBI
Build 361210,805,320 - 210,860,740 (+)NCBI Archive
HuRef1183,415,472 - 183,470,943 (+)NCBI
CHM1_11214,011,558 - 214,066,986 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001040619   ⟹   NP_001035709
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381212,608,761 - 212,620,775 (+)NCBI
GRCh371212,738,676 - 212,794,119 (+)NCBI
Build 361210,848,617 - 210,860,740 (+)NCBI Archive
HuRef1183,415,472 - 183,470,943 (+)NCBI
CHM1_11214,054,831 - 214,066,986 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001206484   ⟹   NP_001193413
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381212,608,761 - 212,620,775 (+)NCBI
GRCh371212,738,676 - 212,794,119 (+)NCBI
HuRef1183,415,472 - 183,470,943 (+)NCBI
CHM1_11214,054,831 - 214,066,986 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001206486   ⟹   NP_001193415
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381212,615,018 - 212,620,777 (+)NCBI
HuRef1183,415,472 - 183,470,943 (+)NCBI
CHM1_11214,061,229 - 214,066,986 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001206488   ⟹   NP_001193417
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381212,608,761 - 212,620,775 (+)NCBI
GRCh371212,738,676 - 212,794,119 (+)NCBI
HuRef1183,415,472 - 183,470,943 (+)NCBI
CHM1_11214,054,831 - 214,066,986 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001674   ⟹   NP_001665
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381212,608,761 - 212,620,775 (+)NCBI
GRCh371212,738,676 - 212,794,119 (+)NCBI
Build 361210,848,617 - 210,860,740 (+)NCBI Archive
HuRef1183,415,472 - 183,470,943 (+)NCBI
CHM1_11214,054,831 - 214,066,986 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005273146   ⟹   XP_005273203
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381212,608,760 - 212,620,775 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011509579   ⟹   XP_011507881
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381212,606,948 - 212,620,775 (+)NCBI
Sequence:
RefSeq Acc Id: XR_001737203
RefSeq Status:
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381212,608,761 - 212,620,775 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001025458 (Get FASTA)   NCBI Sequence Viewer  
  NP_001035709 (Get FASTA)   NCBI Sequence Viewer  
  NP_001193413 (Get FASTA)   NCBI Sequence Viewer  
  NP_001193415 (Get FASTA)   NCBI Sequence Viewer  
  NP_001193417 (Get FASTA)   NCBI Sequence Viewer  
  NP_001665 (Get FASTA)   NCBI Sequence Viewer  
  XP_005273203 (Get FASTA)   NCBI Sequence Viewer  
  XP_011507881 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA20506 (Get FASTA)   NCBI Sequence Viewer  
  AAH06322 (Get FASTA)   NCBI Sequence Viewer  
  AAP35642 (Get FASTA)   NCBI Sequence Viewer  
  AAP93895 (Get FASTA)   NCBI Sequence Viewer  
  AAP93896 (Get FASTA)   NCBI Sequence Viewer  
  AAQ93358 (Get FASTA)   NCBI Sequence Viewer  
  BAB84092 (Get FASTA)   NCBI Sequence Viewer  
  BAC00495 (Get FASTA)   NCBI Sequence Viewer  
  BAC00496 (Get FASTA)   NCBI Sequence Viewer  
  BAC05510 (Get FASTA)   NCBI Sequence Viewer  
  BAD92269 (Get FASTA)   NCBI Sequence Viewer  
  BAG35834 (Get FASTA)   NCBI Sequence Viewer  
  BAG57579 (Get FASTA)   NCBI Sequence Viewer  
  CAG29330 (Get FASTA)   NCBI Sequence Viewer  
  EAW93383 (Get FASTA)   NCBI Sequence Viewer  
  EAW93384 (Get FASTA)   NCBI Sequence Viewer  
  EAW93385 (Get FASTA)   NCBI Sequence Viewer  
  EAW93386 (Get FASTA)   NCBI Sequence Viewer  
  EAW93387 (Get FASTA)   NCBI Sequence Viewer  
  EAW93388 (Get FASTA)   NCBI Sequence Viewer  
  P18847 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001025458   ⟸   NM_001030287
- Peptide Label: isoform 1
- UniProtKB: P18847 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001193413   ⟸   NM_001206484
- Peptide Label: isoform 3
- UniProtKB: P18847 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001035709   ⟸   NM_001040619
- Peptide Label: isoform 2
- UniProtKB: P18847 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001665   ⟸   NM_001674
- Peptide Label: isoform 1
- UniProtKB: P18847 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001193417   ⟸   NM_001206488
- Peptide Label: isoform 3
- UniProtKB: P18847 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001193415   ⟸   NM_001206486
- Peptide Label: isoform 5
- UniProtKB: P18847 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_005273203   ⟸   XM_005273146
- Peptide Label: isoform X1
- UniProtKB: P18847 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_011507881   ⟸   XM_011509579
- Peptide Label: isoform X1
- UniProtKB: P18847 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSP00000432208   ⟸   ENST00000464547
RefSeq Acc Id: ENSP00000336908   ⟸   ENST00000336937
RefSeq Acc Id: ENSP00000483576   ⟸   ENST00000613954
RefSeq Acc Id: ENSP00000480606   ⟸   ENST00000613104
RefSeq Acc Id: ENSP00000355948   ⟸   ENST00000366981
RefSeq Acc Id: ENSP00000355950   ⟸   ENST00000366983
RefSeq Acc Id: ENSP00000355952   ⟸   ENST00000366985
RefSeq Acc Id: ENSP00000355954   ⟸   ENST00000366987
RefSeq Acc Id: ENSP00000344352   ⟸   ENST00000341491
Protein Domains
bZIP

Promoters
RGD ID:6809508
Promoter ID:HG_ACW:5771
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Lymphoblastoid
Transcripts:ATF3.DAPR07
Position:
Human AssemblyChrPosition (strand)Source
Build 361210,846,801 - 210,847,301 (+)MPROMDB
RGD ID:6785328
Promoter ID:HG_KWN:7262
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:ENST00000366981,   ENST00000366985,   ENST00000391902,   NM_001040619,   OTTHUMT00000089296,   OTTHUMT00000089312,   UC009XDG.1
Position:
Human AssemblyChrPosition (strand)Source
Build 361210,847,681 - 210,848,797 (+)MPROMDB
RGD ID:6784657
Promoter ID:HG_KWN:7263
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:HeLa_S3,   K562,   Lymphoblastoid
Transcripts:OTTHUMT00000098525
Position:
Human AssemblyChrPosition (strand)Source
Build 361210,852,426 - 210,854,092 (+)MPROMDB
RGD ID:6785325
Promoter ID:HG_KWN:7264
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:HeLa_S3,   K562,   Lymphoblastoid
Transcripts:ENST00000336937,   ENST00000366983,   ENST00000366984,   OTTHUMT00000089298,   UC001HJJ.1
Position:
Human AssemblyChrPosition (strand)Source
Build 361210,854,136 - 210,855,097 (+)MPROMDB
RGD ID:6858932
Promoter ID:EPDNEW_H2631
Type:initiation region
Name:ATF3_2
Description:activating transcription factor 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H2632  EPDNEW_H2633  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381212,590,387 - 212,590,447EPDNEW
RGD ID:6858934
Promoter ID:EPDNEW_H2632
Type:initiation region
Name:ATF3_1
Description:activating transcription factor 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H2631  EPDNEW_H2633  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381212,608,761 - 212,608,821EPDNEW
RGD ID:6858936
Promoter ID:EPDNEW_H2633
Type:initiation region
Name:ATF3_3
Description:activating transcription factor 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H2631  EPDNEW_H2632  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381212,615,263 - 212,615,323EPDNEW

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 1q31.1-42.11(chr1:187143981-224299417)x3 copy number gain See cases [RCV000051857] Chr1:187143981..224299417 [GRCh38]
Chr1:187113113..224487119 [GRCh37]
Chr1:185379736..222553742 [NCBI36]
Chr1:1q31.1-42.11
pathogenic
GRCh38/hg38 1q32.2-44(chr1:209646207-248931113)x3 copy number gain See cases [RCV000051861] Chr1:209646207..248931113 [GRCh38]
Chr1:209819552..249225312 [GRCh37]
Chr1:207886175..247191935 [NCBI36]
Chr1:1q32.2-44
pathogenic
NM_153606.3(FAM71A):c.274G>A (p.Ala92Thr) single nucleotide variant Malignant melanoma [RCV000060078] Chr1:212625151 [GRCh38]
Chr1:212798493 [GRCh37]
Chr1:210865116 [NCBI36]
Chr1:1q32.3
not provided
NM_153606.3(FAM71A):c.273G>A (p.Pro91=) single nucleotide variant Malignant melanoma [RCV000060077] Chr1:212625150 [GRCh38]
Chr1:212798492 [GRCh37]
Chr1:210865115 [NCBI36]
Chr1:1q32.3
not provided
GRCh38/hg38 1q32.2-44(chr1:209963625-248918469)x3 copy number gain See cases [RCV000134979] Chr1:209963625..248918469 [GRCh38]
Chr1:210136970..249212668 [GRCh37]
Chr1:208203593..247179291 [NCBI36]
Chr1:1q32.2-44
pathogenic
GRCh38/hg38 1q32.1-42.12(chr1:204764914-225408698)x3 copy number gain See cases [RCV000142054] Chr1:204764914..225408698 [GRCh38]
Chr1:204734042..225596400 [GRCh37]
Chr1:203000665..223663023 [NCBI36]
Chr1:1q32.1-42.12
pathogenic
GRCh38/hg38 1q32.2-44(chr1:207346642-248930485)x3 copy number gain See cases [RCV000143727] Chr1:207346642..248930485 [GRCh38]
Chr1:207519987..249224684 [GRCh37]
Chr1:205586610..247191307 [NCBI36]
Chr1:1q32.2-44
pathogenic
GRCh37/hg19 1q31.3-42.13(chr1:197811907-228997888)x3 copy number gain See cases [RCV000240137] Chr1:197811907..228997888 [GRCh37]
Chr1:1q31.3-42.13
pathogenic
GRCh37/hg19 1q31.3-44(chr1:195483439-249213000)x3 copy number gain See cases [RCV000449172] Chr1:195483439..249213000 [GRCh37]
Chr1:1q31.3-44
pathogenic
GRCh37/hg19 1p36.33-q44(chr1:849467-249224684)x3 copy number gain See cases [RCV000510383] Chr1:849467..249224684 [GRCh37]
Chr1:1p36.33-q44
pathogenic
GRCh37/hg19 1p36.33-q44(chr1:849467-249224684) copy number gain See cases [RCV000510926] Chr1:849467..249224684 [GRCh37]
Chr1:1p36.33-q44
pathogenic
GRCh37/hg19 1q32.1-32.3(chr1:204682513-212815646) copy number loss Global developmental delay [RCV000626524] Chr1:204682513..212815646 [GRCh37]
Chr1:1q32.1-32.3
pathogenic
GRCh37/hg19 1p36.33-q44(chr1:47851-249228449)x3 copy number gain not provided [RCV000736295] Chr1:47851..249228449 [GRCh37]
Chr1:1p36.33-q44
pathogenic
GRCh37/hg19 1p36.33-q44(chr1:82154-249218992)x3 copy number gain not provided [RCV000736305] Chr1:82154..249218992 [GRCh37]
Chr1:1p36.33-q44
pathogenic
GRCh37/hg19 1q25.3-41(chr1:185644663-221698833)x3 copy number gain not provided [RCV000749265] Chr1:185644663..221698833 [GRCh37]
Chr1:1q25.3-41
pathogenic
NM_001674.4(ATF3):c.375T>C (p.Asn125=) single nucleotide variant not provided [RCV000918098] Chr1:212619384 [GRCh38]
Chr1:212792726 [GRCh37]
Chr1:1q32.3
benign
GRCh37/hg19 1q32.1-32.3(chr1:206329070-213263817)x3 copy number gain not provided [RCV000848713] Chr1:206329070..213263817 [GRCh37]
Chr1:1q32.1-32.3
uncertain significance
GRCh37/hg19 1q25.3-44(chr1:182388773-249111240)x3 copy number gain not provided [RCV000845852] Chr1:182388773..249111240 [GRCh37]
Chr1:1q25.3-44
pathogenic
GRCh37/hg19 1q32.1-44(chr1:204045948-249218992)x3 copy number gain See cases [RCV001007407] Chr1:204045948..249218992 [GRCh37]
Chr1:1q32.1-44
pathogenic
GRCh37/hg19 1q32.2-44(chr1:210152794-249218992)x3 copy number gain See cases [RCV001194578] Chr1:210152794..249218992 [GRCh37]
Chr1:1q32.2-44
pathogenic

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:785 AgrOrtholog
COSMIC ATF3 COSMIC
Ensembl Genes ENSG00000162772 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSP00000336908 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000344352 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000355948 UniProtKB/TrEMBL
  ENSP00000355950 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000355952 UniProtKB/TrEMBL
  ENSP00000355954 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000432208 UniProtKB/Swiss-Prot
  ENSP00000480606 UniProtKB/Swiss-Prot
  ENSP00000483576 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000336937 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000341491 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000366981 UniProtKB/TrEMBL
  ENST00000366983 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000366985 UniProtKB/TrEMBL
  ENST00000366987 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000464547 UniProtKB/Swiss-Prot
  ENST00000613104 UniProtKB/Swiss-Prot
  ENST00000613954 ENTREZGENE, UniProtKB/Swiss-Prot
GTEx ENSG00000162772 GTEx
HGNC ID HGNC:785 ENTREZGENE
Human Proteome Map ATF3 Human Proteome Map
InterPro AP-1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ATF3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  bZIP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:467 UniProtKB/Swiss-Prot
NCBI Gene 467 ENTREZGENE
OMIM 603148 OMIM
PANTHER PTHR23351 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR23351:SF23 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam bZIP_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  bZIP_2 UniProtKB/TrEMBL
PharmGKB PA25085 PharmGKB
PRINTS LEUZIPPRFOS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE BZIP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  BZIP_BASIC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART BRLZ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniGene Hs.460 ENTREZGENE
UniProt A0A0A0MRJ2_HUMAN UniProtKB/TrEMBL
  ATF3_HUMAN UniProtKB/Swiss-Prot, ENTREZGENE
  Q5VTZ4_HUMAN UniProtKB/TrEMBL
  Q7Z567_HUMAN UniProtKB/TrEMBL
UniProt Secondary Q5VTZ2 UniProtKB/Swiss-Prot
  Q6ICQ9 UniProtKB/Swiss-Prot
  Q7Z566 UniProtKB/Swiss-Prot
  Q8WYM6 UniProtKB/Swiss-Prot